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https://www.readbyqxmd.com/read/28776029/genome-wide-signatures-of-complex-introgression-and-adaptive-evolution-in-the-big-cats
#1
Henrique V Figueiró, Gang Li, Fernanda J Trindade, Juliana Assis, Fabiano Pais, Gabriel Fernandes, Sarah H D Santos, Graham M Hughes, Aleksey Komissarov, Agostinho Antunes, Cristine S Trinca, Maíra R Rodrigues, Tyler Linderoth, Ke Bi, Leandro Silveira, Fernando C C Azevedo, Daniel Kantek, Emiliano Ramalho, Ricardo A Brassaloti, Priscilla M S Villela, Adauto L V Nunes, Rodrigo H F Teixeira, Ronaldo G Morato, Damian Loska, Patricia Saragüeta, Toni Gabaldón, Emma C Teeling, Stephen J O'Brien, Rasmus Nielsen, Luiz L Coutinho, Guilherme Oliveira, William J Murphy, Eduardo Eizirik
The great cats of the genus Panthera comprise a recent radiation whose evolutionary history is poorly understood. Their rapid diversification poses challenges to resolving their phylogeny while offering opportunities to investigate the historical dynamics of adaptive divergence. We report the sequence, de novo assembly, and annotation of the jaguar (Panthera onca) genome, a novel genome sequence for the leopard (Panthera pardus), and comparative analyses encompassing all living Panthera species. Demographic reconstructions indicated that all of these species have experienced variable episodes of population decline during the Pleistocene, ultimately leading to small effective sizes in present-day genomes...
July 2017: Science Advances
https://www.readbyqxmd.com/read/28690147/novel-anaplasma-and-ehrlichia-organisms-infecting-the-wildlife-of-two-regions-of-the-brazilian-amazon
#2
Herbert S Soares, Arlei Marcili, Amália R M Barbieri, Antonio H H Minervino, Antonio F Malheiros, Solange M Gennari, Marcelo B Labruna
During 2009-2012, wild animals were sampled in the Amazon biome of Brazil. Animal tissues and blood were tested by polymerase chain reaction (PCR) assays targeting DNA of the bacterial family Anaplasmataceae (genera Anaplasma, Ehrlichia, Wolbachia) and the genus Borrelia. Overall, 181 wild animals comprising 36 different species (2 reptiles, 5 birds, and 29 mammals) were sampled. All birds and reptiles were negative by all PCR assays, as well as all mammals for the Borrelia PCR assay. Anaplasmataceae agents were searched by PCR assays targeting two different genes, the ribosomal 16S rRNA gene and the protein-coding dsb gene...
July 6, 2017: Acta Tropica
https://www.readbyqxmd.com/read/28677421/molecular-detection-of-viral-agents-in-free-ranging-and-captive-neotropical-felids-in-brazil
#3
Mariana Malzoni Furtado, Sueli Akemi Taniwaki, Iracema Nunes de Barros, Paulo Eduardo Brandão, José Luiz Catão-Dias, Sandra Cavalcanti, Laury Cullen, Claudia Filoni, Anah Tereza de Almeida Jácomo, Rodrigo Silva Pinto Jorge, Nairléia Dos Santos Silva, Leandro Silveira, José Soares Ferreira Neto
We describe molecular testing for felid alphaherpesvirus 1 (FHV-1), carnivore protoparvovirus 1 (CPPV-1), feline calicivirus (FCV), alphacoronavirus 1 (feline coronavirus [FCoV]), feline leukemia virus (FeLV), feline immunodeficiency virus (FIV), and canine distemper virus (CDV) in whole blood samples of 109 free-ranging and 68 captive neotropical felids from Brazil. Samples from 2 jaguars ( Panthera onca) and 1 oncilla ( Leopardus tigrinus) were positive for FHV-1; 2 jaguars, 1 puma ( Puma concolor), and 1 jaguarundi ( Herpairulus yagouaroundi) tested positive for CPPV-1; and 1 puma was positive for FIV...
July 1, 2017: Journal of Veterinary Diagnostic Investigation
https://www.readbyqxmd.com/read/28658274/long-term-monitoring-of-jaguars-in-the-cockscomb-basin-wildlife-sanctuary-belize-implications-for-camera-trap-studies-of-carnivores
#4
Bart J Harmsen, Rebecca J Foster, Emma Sanchez, Carmina E Gutierrez-González, Scott C Silver, Linde E T Ostro, Marcella J Kelly, Elma Kay, Howard Quigley
In this study, we estimate life history parameters and abundance for a protected jaguar population using camera-trap data from a 14-year monitoring program (2002-2015) in Belize, Central America. We investigated the dynamics of this jaguar population using 3,075 detection events of 105 individual adult jaguars. Using robust design open population models, we estimated apparent survival and temporary emigration and investigated individual heterogeneity in detection rates across years. Survival probability was high and constant among the years for both sexes (φ = 0...
2017: PloS One
https://www.readbyqxmd.com/read/28536686/mandible-metastasis-of-small-cell-lung-cancer-mimicking-a-residual-cyst
#5
Renata Mendonça Moraes, Fabio Abreu Alves, Bruna Fernandes do Carmo Carvalho, Felipe D'Almeida Costa, Rodrigo Nascimento Lopes, Graziella Chagas Jaguar
Small cell lung carcinoma (SCLC) is an uncommon tumor characterized by an aggressive behavior with early metastasis, usually to the contralateral lung, liver, brain, and bones. There are only five cases of this particular tumor metastasizing to the oral cavity described in the English literature. We present the case of metastatic SCLC in the mandible with radiographic findings resembling a residual cyst. A 66-year-old man with previous diagnosis and treatment for a SCLC was referred to the Stomatology Department with a history of persistent pain in the mandible 1 year after the inferior right pre-molar tooth extraction...
January 2017: Autopsy & case reports
https://www.readbyqxmd.com/read/28512727/variability-of-high-dose-melphalan-exposure-on-oral-mucositis-in-patients-undergoing-prophylactic-low-level-laser-therapy
#6
Gustavo Henrique Rodrigues, Graziella Chagas Jaguar, Fabio Abreu Alves, Andre Guollo, Vanessa Oliveira Camandoni, Aline Santos Damascena, Vladmir Claudio Cordeiro Lima
The present study outlines the clinical impact and risk factors of oral mucositis in 79 patients with multiple myeloma following high-dose melphalan for autologous transplant. All patients underwent daily prophylactic low-level indium gallium aluminum phosphate diode laser therapy (660 nm, 15 mW, 3.75 J/cm(2), 10 s per point) from the beginning of the conditioning regimen up to day +2. Oral mucositis assessments were made daily until hospital discharge. For analysis, oral mucositis was divided into two groups according to severity: group 1, patients with oral mucositis grade <III (n = 71) and group 2, patients with oral mucositis grade ≥III (n = 8)...
May 16, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28435029/activity-of-carboxylesterases-glutathione-s-transferase-and-monooxygenase-on-rhipicephalus-microplus-exposed-to-fluazuron
#7
Fabrício Nascimento Gaudêncio, Guilherme Marcondes Klafke, Vinícius Menezes Tunholi-Alves, Thaís Paes Ferreira, Cristiane Nunes Coelho, Adivaldo Henrique da Fonseca, Isabele da Costa Angelo, Jairo Pinheiro
The objective of this study was to assess the effect of the exposure to fluazuron on the activity of common pesticide detoxification enzyme groups in the cattle tick (Rhipicephalus microplus). Engorged females of a susceptible strain (POA) and a resistant strain (Jaguar) were exposed in vitro to fluazuron and their eggs and larvae were used to compare the activities of the general esterases, mixed-function oxidases (MFO) and glutathione-S-transferase (GST). The results showed significant elevation in MFO contents and esterases activity in the resistant strain when compared with the susceptible strain, in eggs and larvae respectively...
April 20, 2017: Parasitology International
https://www.readbyqxmd.com/read/28207298/hepatozoon-spp-infect-free-ranging-jaguars-panthera-onca-in-brazil
#8
Mariana Malzoni Furtado, Betina Metzger, Anah Tereza de Almeida Jácomo, Marcelo Bahia Labruna, Thiago Fernandes Martins, Lucia Helena O'Dwyer, Karina Dos Santos Paduan, Grasiela E O Porfírio, Leandro Silveira, Rahel Sollmann, Sueli Akemi Taniwaki, Natália Mundim Tôrres, José Soares Ferreira Neto
This study investigated the presence of Hepatozoon spp. in jaguars ( Panthera onca ) and domestic animals in the Cerrado, Amazon, and Pantanal biomes of Brazil. Between February 2000 and January 2010, blood samples were collected from 30 jaguars, 129 domestic dogs ( Canis lupus familiaris), and 22 domestic cats ( Felis catus ) for molecular tests. All of the jaguars from the Pantanal (n = 22) and Cerrado (n = 4) and 3 of 4 jaguars from the Amazon were positive for Hepatozoon spp. Domestic dogs (62.8%) and cats (31...
June 2017: Journal of Parasitology
https://www.readbyqxmd.com/read/28196774/is-the-free-ranging-jaguar-panthera-onca-a-reservoir-for-cytauxzoon-felis-in-brazil
#9
Mariana Malzoni Furtado, Sueli Akemi Taniwaki, Betina Metzger, Karina Dos Santos Paduan, Helena Lucia O'Dwyer, Anah Tereza de Almeida Jácomo, Grasiela E O Porfírio, Leandro Silveira, Rahel Sollmann, Natália Mundim Tôrres, José Soares Ferreira Neto
This study investigated the occurrence of Cytauxzoon felis and Babesia spp. in free-ranging jaguars (Panthera onca), domestic dogs (Canis lupus familiaris) and domestic cats (Felis catus) from the Cerrado, Amazon and Pantanal biomes of Brazil. Blood samples were collected from 30 jaguars, 129 dogs and 22 cats for detection of the 18S rRNA genes of piroplasmids. All of the jaguars from the Pantanal (n=22) and Cerrado (n=4) and three of four jaguars from the Amazon were positive for C. felis, but no dogs or cats were positive for the agent...
February 6, 2017: Ticks and Tick-borne Diseases
https://www.readbyqxmd.com/read/28188582/attitudes-toward-jaguars-and-pumas-and-the-acceptability-of-killing-big-cats-in-the-brazilian-atlantic-forest-an-application-of-the-potential-for-conflict-index2
#10
Monica T Engel, Jerry J Vaske, Alistair J Bath, Silvio Marchini
We explored the overall acceptability of killing jaguars and pumas in different scenarios of people-big cat interactions, the influence of attitudes toward big cats on acceptability, and the level of consensus on the responses. Data were obtained from 326 self-administered questionnaires in areas adjacent to Intervales State Park and Alto Ribeira State Park. Overall, people held slightly positive attitudes toward jaguars and pumas and viewed the killing of big cats as unacceptable. However, individuals that held negative attitudes were more accepting of killing...
February 10, 2017: Ambio
https://www.readbyqxmd.com/read/28133569/jaguar-interactions-with-pumas-and-prey-at-the-northern-edge-of-jaguars-range
#11
Carmina E Gutiérrez-González, Carlos A López-González
We present the first study that evaluates jaguar-puma interactions in the arid lands of northern Mexico, where jaguars have their northernmost breeding population and both predators are persecuted for livestock depredation. We tested whether jaguars are the dominant species in this unique ecosystem, where: (1) pumas outnumber jaguars, (2) pumas are better adapted to arid environments, and (3) jaguars and pumas are of similar size. We analyzed four years of data with two approaches; a two species conditional occupancy model and an activity patterns analysis...
2017: PeerJ
https://www.readbyqxmd.com/read/28043351/reproductive-analysis-of-male-and-female-captive-jaguars-panthera-onca-in-a-colombian-zoological-park
#12
Santiago Jimenez Gonzalez, Jo Gayle Howard, Janine Brown, Henry Grajales, Jorge Pinzón, Haydy Monsalve, María Angélica Moreno, Claudia Jimenez Escobar
A reproductive analysis of a captive group of jaguars (Panthera onca; n = 6) at the Santacruz Zoological Foundation in Cundinamarca, Colombia, was conducted by performing a longitudinal, noninvasive, hormonal analysis of estradiol and progestogens in females and of androgens in males. During four seasons, female jaguars confined in solitary were evaluated for ovarian activity and spontaneous ovulation, male jaguars for testicular activity. A second hormonal follow-up was conducted in the females after administration of gonadotropins...
February 2017: Theriogenology
https://www.readbyqxmd.com/read/28030568/space-use-and-movement-of-a-neotropical-top-predator-the-endangered-jaguar
#13
Ronaldo G Morato, Jared A Stabach, Chris H Fleming, Justin M Calabrese, Rogério C De Paula, Kátia M P M Ferraz, Daniel L Z Kantek, Selma S Miyazaki, Thadeu D C Pereira, Gediendson R Araujo, Agustin Paviolo, Carlos De Angelo, Mario S Di Bitetti, Paula Cruz, Fernando Lima, Laury Cullen, Denis A Sana, Emiliano E Ramalho, Marina M Carvalho, Fábio H S Soares, Barbara Zimbres, Marina X Silva, Marcela D F Moraes, Alexandre Vogliotti, Joares A May, Mario Haberfeld, Lilian Rampim, Leonardo Sartorello, Milton C Ribeiro, Peter Leimgruber
Accurately estimating home range and understanding movement behavior can provide important information on ecological processes. Advances in data collection and analysis have improved our ability to estimate home range and movement parameters, both of which have the potential to impact species conservation. Fitting continuous-time movement model to data and incorporating the autocorrelated kernel density estimator (AKDE), we investigated range residency of forty-four jaguars fit with GPS collars across five biomes in Brazil and Argentina...
2016: PloS One
https://www.readbyqxmd.com/read/28012903/multiple-host-pathogens-in-domestic-hunting-dogs-in-nicaragua-s-bosaw%C3%A3-s-biosphere-reserve
#14
Christine V Fiorello, Mary H Straub, Laura M Schwartz, James Liu, Amanda Campbell, Alexa K Kownacki, Janet E Foley
Nicaragua's Bosawás Biosphere Reserve is a vast forested area inhabited largely by indigenous Mayangna and Miskitu people. Most Bosawás residents rely on subsistence hunting and swidden agriculture, and hunting dogs are important for finding and securing wild game. We investigated the health of hunting dogs in three communities differing in location, size, and economy. Dogs in all communities were nutritionally compromised and experienced a heavy burden of disease. Seroprevalence of canine distemper, canine parvovirus, Rickettsia rickettsii, and Leptospira spp...
March 2017: Acta Tropica
https://www.readbyqxmd.com/read/27973584/implications-of-fine-grained-habitat-fragmentation-and-road-mortality-for-jaguar-conservation-in-the-atlantic-forest-brazil
#15
Laury Cullen, Jessica C Stanton, Fernando Lima, Alexandre Uezu, Miriam L L Perilli, H Reşit Akçakaya
Jaguar (Panthera onca) populations in the Upper Paraná River, in the Brazilian Atlantic Forest region, live in a landscape that includes highly fragmented areas as well as relatively intact ones. We developed a model of jaguar habitat suitability in this region, and based on this habitat model, we developed a spatially structured metapopulation model of the jaguar populations in this area to analyze their viability, the potential impact of road mortality on the populations' persistence, and the interaction between road mortality and habitat fragmentation...
2016: PloS One
https://www.readbyqxmd.com/read/27951674/multiconformation-density-functional-theory-based-pka-prediction-in-application-to-large-flexible-organic-molecules-with-diverse-functional-groups
#16
Art D Bochevarov, Mark A Watson, Jeremy R Greenwood, Dean M Philipp
We consider the conformational flexibility of molecules and its implications for micro- and macro-pKa. The corresponding formulas are derived and discussed against the background of a comprehensive scientific and algorithmic description of the latest version of our computer program Jaguar pKa, a density functional theory-based pKa predictor, which is now capable of acting on multiple conformations explicitly. Jaguar pKa is essentially a complex computational workflow incorporating research and technologies from the fields of cheminformatics, molecular mechanics, quantum mechanics, and implicit solvation models...
December 13, 2016: Journal of Chemical Theory and Computation
https://www.readbyqxmd.com/read/27928654/using-certified-timber-extraction-to-benefit-jaguar-and-ecosystem-conservation
#17
REVIEW
John Polisar, Benoit de Thoisy, Damián I Rumiz, Fabricio Díaz Santos, Roan Balas McNab, Rony Garcia-Anleu, Gabriela Ponce-Santizo, Rosario Arispe, Claudia Venegas
The jaguar Panthera onca requires large areas of relatively intact habitats containing adequate amounts of prey to survive. Since a substantial portion of jaguar range occurs outside of strict protected areas, there is a need for economic incentives for habitat conservation, which carefully managed selective logging can provide. Forest Stewardship Council and Pan European Forest Council certifications intended to regulate wood extraction to maintain the ecological functions of forests require evidence of biodiversity and ecosystem conservation...
December 7, 2016: Ambio
https://www.readbyqxmd.com/read/27918737/influence-of-bethanechol-on-salivary-parameters-in-irradiated-patients
#18
C Cotomacio, L Campos, A Simões, G Jaguar, E-M Crosato, F Abreu-Alves
BACKGROUND: Some studies have shown evidence that the prophylactic use of bethanechol chloride (BC) may be useful in preventing the incidence and/or severity of xerostomia (XT). However, the indication of BC in irradiated patients with XT needs to be better characterized. The study aimed to evaluate the influence of BC on XT, salivary flow rate, and salivary composition in patients previously submitted to head and neck radiotherapy. MATERIAL AND METHODS: Forty five irradiated patients complaining of XT used 50 mg/day of BC for 3 months, and the salivary parameters were evaluated in 4 Phases (Before BC therapy, after one month of BC, 2 months of BC, and 3 months of BC)...
January 1, 2017: Medicina Oral, Patología Oral y Cirugía Bucal
https://www.readbyqxmd.com/read/27898922/influence-of-pork-and-pork-by-products-on-macronutrient-and-energy-digestibility-and-palatability-in-large-exotic-felids
#19
C J Iske, C L Morris, K L Kappen
Two experiments were conducted to evaluate digestibility and palatability of a new commercial pork-based raw diet for zoo-managed felids. Currently 2 protein sources (beef or horse) comprise the majority of commercial raw meat diet formulations for exotic carnivores in zoological institutions. Pork-based diets have traditionally not been widely utilized and thus nutrient digestibility of pork has not been adequately evaluated in exotic carnivores. The objectives of this study were 1) to determine if a pork-based diet had similar apparent total tract macronutrient digestibility and fecal scores as standard zoo carnivore diets formulated with either horse or beef, in large exotic felids and 2) evaluate palatability of pork for use in zoos...
September 2016: Journal of Animal Science
https://www.readbyqxmd.com/read/27869944/evaluation-of-drug-prescription-quality-indicators-in-a-primary-health-care-facility-with-different-models-of-health-care
#20
Daniela Oliveira de Melo, Sílvia Regina Ansaldi da Silva, Lia Lusitana Cardozo de Castro
OBJECTIVE: to describe drug prescription indicators in a primary health care facility with different models of health care. METHODS: this was a descriptive study using secondary data of prescriptions with regard to quality indicators in a health facility that has three health care models: Outpatient Medical Care (OMC), Primary Health Care Unit (PHU) and Family Health Strategy (FHS) in Vila Nova Jaguaré OMC/PHU in São Paulo-SP, Brazil, from July to October 2011...
April 2016: Epidemiologia e Servicos de Saude: Revista do Sistema Unico de Saude do Brasil
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