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https://www.readbyqxmd.com/read/28325024/balance-quality-assessment-as-an-early-indicator-of-physical-frailty-in-older-people
#1
Aly Chkeir, Doha Safieddine, D Bera, M Collart, J L Novella, M Drame, David J Hewson, Jacques Duchene
Frailty is an increasingly common geriatric condition that results in an increased risk of adverse health outcomes such as falls. The most widely-used means of detecting frailty is the Fried phenotype, which includes several objective measures such as grip strength and gait velocity. One method of screening for falls is to measure balance, which can be done by a range of techniques including the assessment of the Centre of Pressure (CoP) during a balance assessment. The Balance Quality Tester (BQT) is a device based on a commercial bathroom scale that can evaluate balance quality...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28324618/thermogelling-chitosan-lactate-hydrogel-improves-functional-recovery-after-a-c2-spinal-cord-hemisection-in-rat
#2
Katarzyna Nawrotek, Tanguy Marqueste, Zofia Modrzejewska, Roman Zarzycki, Agnieszka Rusak, Patrick Decherchi
The present study was designed to provide an appropriate micro-environment for regenerating axotomized neurons and proliferating/migrating cells. Because of its intrinsic permissive properties, biocompatibility and biodegradability, we chose to evaluate the therapeutic effectiveness of a chitosan-based biopolymer. The biomaterial toxicity was measured through in vitro test based on fibroblast cell survival on thermogelling chitosan lactate hydrogel substrate and then polymer was implanted into a C2 hemisection of the rat spinal cord...
March 21, 2017: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/28318630/sarcopenia-and-its-individual-criteria-are-associated-in-part-with-mortality-among-patients%C3%A2-on-hemodialysis
#3
Piyawan Kittiskulnam, Glenn M Chertow, Juan J Carrero, Cynthia Delgado, George A Kaysen, Kirsten L Johansen
The relative importance of sarcopenia and its individual components as independent predictors of mortality in the dialysis population has not been determined. We estimated whole-body muscle mass using pre-dialysis bioimpedance spectroscopy measurements in 645 ACTIVE/ADIPOSE-enrolled prevalent hemodialysis patients from San Francisco and Atlanta. Low muscle mass was defined as two standard deviations below sex-specific means for young adults from NHANES and indexed to height(2), body weight, body surface area, or body mass index...
March 16, 2017: Kidney International
https://www.readbyqxmd.com/read/28318306/physical-education-and-sport
#4
Paul D Loprinzi, Bradley J Cardinal, Marita K Cardinal, Charles B Corbin
PURPOSE: The purpose of this study was to examine the associations between physical education (PE) and sports involvement with physical activity (PA), physical fitness, and beliefs about PA among a national sample of adolescents. SETTING: Data from the National Health and Nutrition Examination Survey National Youth Fitness Survey were used. PARTICIPANTS: A total of 459 adolescents aged 12 to 15 years. MEASURES: Adolescents self-reported engagement in the above parameters; muscular fitness objectively determined...
January 1, 2017: American Journal of Health Promotion: AJHP
https://www.readbyqxmd.com/read/28315777/appetite-disorders-in-cancer-patients-impact-on-nutritional-status-and-quality-of-life
#5
David E Barajas Galindo, Alfonso Vidal-Casariego, Alicia Calleja-Fernández, Ana Hernández-Moreno, Begoña Pintor de la Maza, Manuela Pedraza-Lorenzo, María Asunción Rodríguez-García, Dalia María Ávila-Turcios, Miran Alejo-Ramos, Rocío Villar-Taibo, Ana Urioste-Fondo, Isidoro Cano-Rodríguez, María D Ballesteros-Pomar
Cancer patients are at high risk of malnutrition due to several symptoms such as lack of appetite. The aim of this study was to determine the prevalence of different appetite disorders in cancer patients and their influence on dietary intake, nutritional status, and quality of life. We conducted a cross-sectional study of cancer patients at risk of malnutrition. Nutritional status was studied using Subjective Global Assessment, anthropometry, and grip strength. Dietary intake was evaluated with a 24-hour recall, and patients were questioned about the presence of changes in appetite (none, anorexia, early satiety, or both)...
March 15, 2017: Appetite
https://www.readbyqxmd.com/read/28306145/functional-status-modifies-the-association-of-blood-pressure-with-death-in-elders-health-and-retirement-study
#6
Chenkai Wu, Ellen Smit, Carmen A Peralta, Harini Sarathy, Michelle C Odden
OBJECTIVE: To examine whether grip strength, gait speed, and the combination of the two physical functioning measures modified the association of systolic BP (SBP) and diastolic BP (DBP) with mortality. DESIGN: Nationally representative cohort study. SETTING: Health and Retirement Study. PARTICIPANTS: 7,492 U.S. adults aged ≥65 years. MEASUREMENTS: Grip strength was measured by a hand dynamometer and classified as normal (≥16 kg for female; ≥26 kg for male) and weak...
March 17, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28303562/association-between-actn3-r577x-polymorphism-and-trunk-flexibility-in-2-different-cohorts
#7
Naoki Kikuchi, Hirofumi Zempo, Noriyuki Fuku, Haruka Murakami, Mikako Sakamaki-Sunaga, Takanobu Okamoto, Koichi Nakazato, Motohiko Miyachi
α-Actinin-3 (ACTN3) R577X polymorphism is associated with muscular strength and power. This study was performed to investigate the association between ACTN3 R577X polymorphisms and flexibility as another component of fitness in 2 cohorts. Cohort 1 consisted of 208 men and 568 women (ages 23-88), while Cohort 2 consisted of 529 men and 728 women (ages 23-87). All participants were recruited from the Tokyo metropolitan area and underwent a battery of tests to assess their grip strength and sit-and-reach flexibility...
March 16, 2017: International Journal of Sports Medicine
https://www.readbyqxmd.com/read/28302751/impact-of-the-clinical-frailty-scale-on-outcomes-after-transcatheter-aortic-valve-replacement
#8
Tetsuro Shimura, Masanori Yamamoto, Seiji Kano, Ai Kagase, Atsuko Kodama, Yutaka Koyama, Etsuo Tsuchikane, Takahiko Suzuki, Toshiaki Otsuka, Shun Kohsaka, Norio Tada, Futoshi Yamanaka, Toru Naganuma, Motoharu Araki, Shinichi Shirai, Yusuke Watanabe, Kentaro Hayashida
Background -The semi-quantitative clinical frailty scale (CFS) is a simple tool to assess patient`s frailty and has been shown to correlate with mortality in elderly patients even when evaluated by non-geriatricians. The aim of the current study was to determine the prognostic value of CFS in patients who underwent transcatheter aortic valve replacement (TAVR). Methods -We utilized the Optimized CathEter vAlvular iNtervention (OCEAN) Japanese multicenter registry to review data of 1215 patients who underwent TAVR...
March 16, 2017: Circulation
https://www.readbyqxmd.com/read/28299916/relationship-between-patient-reported-and-objective-measurements-of-hand-function-in-patients-with-rheumatoid-arthritis
#9
S M Günay, Z Tuna, D Oskay
Rheumatoid arthritis (RA) often results in impairments in upper extremities, especially in the small joints of hand. Involvement of hand brings limitations in activities of daily living. However, it is commonly observed that patient-reported functional status of hand does not always corresponds to their actual physical performance in the clinical setting. The aim of this pilot study is to investigate the relationship between patient self-reported and objectively measured hand functions in patients with RA. Twenty-six patients (51±13 years) with RA diagnosis participated in the study...
December 31, 2016: Reumatismo
https://www.readbyqxmd.com/read/28299202/the-role-for-infarct-volume-as-a-surrogate-measure-of-functional-outcome-following-ischemic-stroke
#10
Ryan C Turner, Kenneth DiPasquale, Aric F Logsdon, Zhenjun Tan, Zachary J Naser, Jason D Huber, Charles L Rosen, Brandon P Lucke-Wold
The failed translation of proposed therapeutic agents for ischemic stroke from preclinical to clinical studies has led to increased scrutiny of preclinical studies, namely the model and outcome measures utilized. Preclinical studies routinely use infarct volume as an experimental endpoint or measure in studies employing young-adult, healthy male animals despite the fact that clinically, ischemic stroke is a disease of the elderly and improvements in functional outcome from pre- to post-intervention remains the most widely utilized assessment...
December 2016: Journal of Systems and Integrative Neuroscience
https://www.readbyqxmd.com/read/28295612/relationship-between-pre-transplant-physical-function-and-outcomes-after-kidney-transplant-elizabeth
#11
C Lorenz, Andrea L Cheville, Hatem Amer, Brian R Kotajarvi, Mark D Stegall, Tanya M Petterson, Walter K Kremers, Fernando G Cosio, Nathan K LeBrasseur
BACKGROUND: Performance-based measures of physical function predict morbidity following non-transplant surgery. Study objectives were to determine whether physical function predicts outcomes after kidney transplant and assess how physical function changes post-transplant. METHODS: We conducted a prospective study involving living donor kidney transplants recipients at our center 5/2012 to 2/2014. Physical function was measured using the Short Physical Performance Battery (SPPB) (balance, chair stands, gait speed) and grip strength testing...
March 11, 2017: Clinical Transplantation
https://www.readbyqxmd.com/read/28295144/androgen-receptor-polyglutamine-repeat-length-ar-cagn-modulates-the-effect-of-testosterone-on-androgen-associated-somatic-traits-in-filipino-young-adult-men
#12
Calen P Ryan, Alexander V Georgiev, Thomas W McDade, Lee T Gettler, Dan T A Eisenberg, Margarita Rzhetskaya, Sonny S Agustin, M Geoffrey Hayes, Christopher W Kuzawa
OBJECTIVES: The androgen receptor (AR) mediates expression of androgen-associated somatic traits such as muscle mass and strength. Within the human AR is a highly variable glutamine short-tandem repeat (AR-CAGn), and CAG repeat number has been inversely correlated to AR transcriptional activity in vitro. However, evidence for an attenuating effect of long AR-CAGn on androgen-associated somatic traits has been inconsistent in human populations. One possible explanation for this lack of consistency is that the effect of AR-CAGn on AR bioactivity in target tissues likely varies in relation to circulating androgen levels...
March 14, 2017: American Journal of Physical Anthropology
https://www.readbyqxmd.com/read/28294567/growth-hormone-secretagogues-prevent-dysregulation-of-skeletal-muscle-calcium-homeostasis-in-a-rat-model-of-cisplatin-induced-cachexia
#13
Elena Conte, Giulia Maria Camerino, Antonietta Mele, Michela De Bellis, Sabata Pierno, Francesco Rana, Adriano Fonzino, Roberta Caloiero, Laura Rizzi, Elena Bresciani, Khoubaib Ben Haj Salah, Jean-Alain Fehrentz, Jean Martinez, Arcangela Giustino, Maria Addolorata Mariggiò, Mauro Coluccia, Domenico Tricarico, Marcello Diego Lograno, Annamaria De Luca, Antonio Torsello, Diana Conte, Antonella Liantonio
BACKGROUND: Cachexia is a wasting condition associated with cancer types and, at the same time, is a serious and dose-limiting side effect of cancer chemotherapy. Skeletal muscle loss is one of the main characteristics of cachexia that significantly contributes to the functional muscle impairment. Calcium-dependent signaling pathways are believed to play an important role in skeletal muscle decline observed in cachexia, but whether intracellular calcium homeostasis is affected in this situation remains uncertain...
March 10, 2017: Journal of Cachexia, Sarcopenia and Muscle
https://www.readbyqxmd.com/read/28291438/isokinetic-evaluation-of-wrist-muscle-strength-in-patients-of-carpal-tunnel-syndrome
#14
Mehmet Ağırman, Adnan Kara, Oğuz Durmuş, İlknur Saral, Engin Çakar
OBJECTIVES: This study aims to investigate the isokinetic characteristics of wrist strength in flexion, extension, supination, pronation, radial, and ulnar deviation in patients with moderate or severe carpal tunnel syndrome (CTS). PATIENTS AND METHODS: Thirteen patients (23 hands) (2 males, 11 females; mean age 45 years; range 29 to 60 years) with moderate or severe CTS were compared to six healthy control subjects (12 hands) (2 males, 4 females; mean age 41 years; range 27 to 63 years) in this study, which was conducted between January 2016 and April 2016...
April 2017: Eklem Hastalıkları Ve Cerrahisi, Joint Diseases & related Surgery
https://www.readbyqxmd.com/read/28290940/effects-of-combat-deployment-on-anthropometrics-and-physiological-status-of-u-s-army-special-operations-forces-soldiers
#15
Emily K Farina, Jonathan C Taylor, Gary E Means, Kelly W Williams, Nancy E Murphy, Lee M Margolis, Stefan M Pasiakos, Harris R Lieberman, James P McClung
INTRODUCTION: U.S. Army Special Operations Forces (SOF) soldiers deploy frequently and conduct military operations through special warfare and surgical strike capabilities. Tasks required to execute these capabilities may induce physical and mental stress and have the potential to degrade soldier physiological status. No investigations have longitudinally characterized whether combat deployment alters anthropometrics or biochemical markers of physiological status in a SOF population of frequent deployers...
March 2017: Military Medicine
https://www.readbyqxmd.com/read/28289561/comparison-of-hand-grip-strength-and-upper-limb-pressure-pain-threshold-between-older-adults-with-or-without-non-specific-shoulder-pain
#16
Cesar Calvo Lobo, Carlos Romero Morales, David Rodríguez Sanz, Irene Sanz Corbalán, Eleuterio A Sánchez Romero, Josué Fernández Carnero, Daniel López López
BACKGROUND: There is a high prevalence of non-specific shoulder pain associated with upper limb functional limitations in older adults. The purpose of this study was to determine the minimal clinically important differences (MCID) of grip strength and pressure pain threshold (PPT) in the upper limb between older adults with or without non-specific shoulder pain. METHODS: A case-control study was carried out following the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) criteria...
2017: PeerJ
https://www.readbyqxmd.com/read/28287324/the-effect-of-a-home-delivery-meal-service-of-energy-and-protein-rich-meals-on-quality-of-life-in-malnourished-outpatients-suffering-from-lung-cancer-a-randomized-controlled-trial
#17
Eva Leedo, Josephine Gade, Sabrina Granov, Anders Mellemgaard, Tobias Wirenfeldt Klausen, Katrine Rask, Arne Astrup
Undernutrition is prevalent in cancer patients and associated with increased incidence of complications and mortality. We investigated the effects of a home delivery meal service, providing a selection of energy-dense, protein-rich meals, on quality of life (QoL) in malnourished lung cancer patients. Forty lung cancer patients with nutritional risk score ≥3 (NRS-2002) were randomized to control or intervention. The intervention group was offered energy- and protein-rich main meals and snacks, delivered 3 times per week...
April 2017: Nutrition and Cancer
https://www.readbyqxmd.com/read/28286250/change-in-muscle-strength-and-muscle-mass-in-older-hospitalized-patients-a-systematic-review-and-meta-analysis
#18
Jeanine M Van Ancum, Kira Scheerman, Nini H Jonkman, Hanne E Smeenk, Roeliene C Kruizinga, Carel G M Meskers, Andrea B Maier
Hospitalization may induce a decrease of muscle strength and muscle mass in older patients due to physical inactivity, malnutrition and diseases, negatively affecting health outcome. We aimed to examine the literature on change in muscle strength and muscle mass in older patients during hospitalization. A literature search was performed in major electronic databases from inception to March 2016. Studies including hospitalized patients with a mean age≥65years, describing change of hand grip strength and/or muscle mass were found eligible...
March 10, 2017: Experimental Gerontology
https://www.readbyqxmd.com/read/28285090/assessment-of-the-ipsilesional-hand-function-in-stroke-survivors-the-effect-of-lesion-side
#19
Bianca Pinto Cunha, Sandra Maria Sbeghen Ferreira de Freitas, Paulo Barbosa de Freitas
BACKGROUND: The aim of this study was to examine the effect of the side of brain lesion on the ipsilesional hand function of stroke survivors. METHODS: Twenty-four chronic stroke survivors, equally allocated in 2 groups according to the side of brain lesion (right or left), and 12 sex- and age-matched healthy controls performed the Jebsen-Taylor Hand Function Test (JTHFT), the Nine-Hole Peg Test (9HPT), the maximum power grip strength (PwGSmax) test, and the maximum pinch grip strength (PnGSmax) test...
March 8, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28281192/reliability-of-thermodilution-derived-cardiac-output-with-different-operator-characteristics
#20
Scott C McKenzie, Kimble Dunster, Wandy Chan, Martin R Brown, David G Platts, George Javorsky, Chris Anstey, Shaun D Gregory
Cardiac output (CO) is commonly measured using the thermodilution technique at the time of right heart catheterisation (RHC). However inter-operator variability, and the operator characteristics which may influence that, has not been quantified. Therefore, this study aimed to assess inter-operator variability with the thermodilution technique using a mock circulation loop (MCL) with calibrated flow sensors. Participants were blinded and asked to determine 4 levels of CO using the thermodilution technique, which was compared with the MCL calibrated flow sensors...
March 9, 2017: Journal of Clinical Monitoring and Computing
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