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https://www.readbyqxmd.com/read/29431098/multiloculated-mesothelial-cyst-presenting-as-a-malignant-mimic
#1
June S Peng, Lisa Park, Sricharan Chalikonda, Scott E Kilpatrick
A 46-year-old woman was referred for a second opinion regarding an intra-abdominal mass discovered on imaging performed for abdominal pain and distension. The tumour appeared to involve the small bowel, left colon and mesentery and was initially thought to be consistent with an infiltrative tumour or loculated mucinous ascites. Due to the unusual appearance of the tumour and suspicion for an omental-based mass, a laparoscopic resection was recommended to the patient. Intraoperatively, the tumour was found to be a multiloculated, benign appearing, omental cyst without involvement of the bowel and was completely resected laparoscopically...
February 3, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29411667/prognosis-of-patients-with-ascites-after-pleurx-insertion-an-observational-study
#2
Agnete Nordheim Riedel, Nina Kimer, Lise Hobolth, Lise Lotte Gluud
OBJECTIVE: To evaluate the safety of PleurX in cirrhotic patients with refractory ascites. METHODS: We prospectively registered patients who received a PleurX catheter cirrhosis-associated refractory ascites at our department from July 2015 to November 2016. Our control group consisted of matched cirrhotic patients with refractory ascites treated with large volume paracentesis (LVP) and patients with malignant ascites treated with PleurX during the same period. RESULTS: We included 25 patients with cirrhosis-related ascites (7 in PleurX group) and 17 with malignant ascites (14 in PleurX group)...
February 7, 2018: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/29406040/community-or-healthcare-associated-bacterial-infections-increase-long-term-mortality-in-patients-with-acute-decompensation-of-cirrhosis
#3
Hong Zhao, Yu Shi, Huihui Dong, Jianhua Hu, Xuan Zhang, Meifang Yang, Jun Fan, Weihang Ma, Jifang Sheng, Lanjuan Li
BACKGROUND: The aim of the present study was to determine the specific role of different types of bacterial infections (BIs) on the prognosis of cirrhotic patients with acute decompensation (AD). METHODS: We performed a prospective, observational cohort study consisting of 492 cirrhotic patients with AD at our center from February 2014 to March 2015. Clinical, laboratory and survival data were collected. The relationship between BIs and mortality was analyzed. RESULTS: BIs were identified in 157 of 492 patients at the time of admission or during the hospital stay...
February 2018: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/29394565/-mixed-type-liposarcoma-with-intra-abdominal-bleeding-report-of-a-case
#4
Yohei Miura, Jun Sakata, Takuya Ando, Daiki Soma, Kizuki Yuza, Yuki Hirose, Hirosuke Ishikawa, Kohei Miura, Kazuyasu Takizawa, Takashi Kobayashi, Hiroshi Ichikawa, Masayuki Nagahashi, Yoshifumi Shimada, Hitoshi Kameyama, Toshifumi Wakai
A 71-year-old man presented with sudden abdominal pain. He had past history of atrial fibrillation, cerebral infarction and heart-valve replacement and received anticoagulant therapy with warfarin. Computed tomography of the abdomen revealed bloody ascites and a huge mass in contact with the third portion of the duodenum. The mass was encapsulated and consisted of a solid component with calcification and hematoma. Under the preoperative diagnosis of gastrointestinal stromal tumor with intra-abdominal bleeding, laparotomy was performed...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29379166/aggressive-serous-epithelial-ovarian-cancer-is-potentially-propagated-by-epcam-cd45-phenotype
#5
Md Zahid Akhter, Surender K Sharawat, Vikash Kumar, Veena Kochat, Zaffar Equbal, Mallika Ramakrishnan, Umesh Kumar, Sandeep Mathur, Lalit Kumar, Asok Mukhopadhyay
Epithelial ovarian carcinoma (EOC) patients often acquire resistance against common chemotherapeutic drugs like paclitaxel and cisplatin. The mechanism responsible for the same is ambiguous. We have identified a putative drug-resistant tumour cell phenotype (EpCAM+CD45+) in the ascitic fluid of EOC patients, which appears to originate from the primary tumour. These cells represent the major tumour burden and are more drug resistant compared to EpCAM+tumour cells due to the over-expression of SIRT1, ABCA1 and BCL2 genes...
January 30, 2018: Oncogene
https://www.readbyqxmd.com/read/29377355/gallbladder-agenesis-in-17-dogs-2006-2016
#6
K Sato, M Sakai, S Hayakawa, Y Sakamoto, Y Kagawa, K Kutara, K Teshima, K Asano, T Watari
BACKGROUND: Gallbladder agenesis (GBA) is extremely rare in dogs. HYPOTHESIS/OBJECTIVES: To describe the history, clinical signs, diagnosis, treatment, and outcomes of dogs with GBA. ANIMALS: Seventeen client-owned dogs with GBA. METHODS: Medical records from 2006 through 2016 were retrospectively reviewed. Dogs were included when GBA was suspected on abdominal ultrasonography and confirmed by gross evaluation. Signalment, clinical signs, clinicopathological data, diagnostic imaging, histopathology, treatment, and outcome were recorded...
January 2018: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/29374723/low-dose-pressurized-intrathoracic-aerosol-chemotherapy-pitac-as-an-alternative-therapy-for-pleuropulmonary-involvement-in-pseudomyxoma-peritonei
#7
Manuela Robella, Marco Vaira, Alice Borsano, Claudio Mossetti, Michele DE Simone
BACKGROUND/AIM: Pseudomyxoma peritonei (PMP) is a rare disease characterized by mucinous ascites and widespread peritoneal implants. It usually originates from the rupture of an adenoma/adenocarcinoma of the appendix. Although this tumor is only superficially invasive and does not metastasize, it could be a fatal disease. Extra-abdominal spread of PMP is an unusual occurrence with few reports in medical literature. CASE REPORT: A 50-year-old man was diagnosed with PMP according to the findings of thorax and abdomen CT scan and cytologic and histological examinations...
February 2018: Anticancer Research
https://www.readbyqxmd.com/read/29333010/sinusoidal-obstruction-syndrome-during-treatment-for-wilms-tumor-a-life-threatening-complication
#8
Sidharth Totadri, Amita Trehan, Deepak Bansal, Richa Jain
Context: Survival rates exceed 90% in Wilms' tumor (WT). Actinomycin-D (ACT-D) which is indispensable in the management of WT is associated with the development of sinusoidal obstruction syndrome (SOS), a potentially fatal complication. Aims: The aim is to study the presentation, management, and outcome of SOS complicating ACT-D administration in WT. Settings and Design: Retrospective file review conducted in a Pediatric Hematology-Oncology unit...
October 2017: Indian Journal of Medical and Paediatric Oncology
https://www.readbyqxmd.com/read/29227858/bilateral-ovarian-angiosarcoma-arising-from-the-mature-cystic-teratomas-a-case-report-and-review-of-the-literature
#9
Erik Kudela, Marcela Nachajova, Kamil Biringer, Pavol Slavik, Lukas Plank, Jan Danko
INTRODUCTION: Ovarian teratomas undergo the malignant transformation in 0.2-2% of cases. The behavior of malignancies in mature cystic teratomas (MCT) is determined by their phenotype and not their derivation from germ cells. We can recognize pure angiosarcomas or as a part of other tumors like malignant mixed Mullerian tumors and adenosarcomas. PRESENTATION OF CASE: We present the first case of bilateral ovarian angiosarcoma arising from the mature teratomas. Due to widespread disease, we performed limited surgical procedure consisting of bilateral adnexectomy and omentectomy...
December 7, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29224115/ct-features-for-diagnosing-acute-torsion-of-uterine-subserosal-leiomyoma
#10
Yoshimitsu Ohgiya, Noritaka Seino, Shingo Miyamoto, Nobuyuki Takeyama, Kumi Hatano, Jiro Munechika, Kumiko Ishizuka, Masanori Hirose, Nobuyuki Ohike, Toshi Hashimoto, Akihiko Sekizawa, Takehiko Gokan
PURPOSE: To evaluate the usefulness of computed tomographic (CT) features for identifying acute torsion of uterine subserosal leiomyoma (USL). SUBJECTS AND METHODS: We analyzed contrast-enhanced CT examinations of 7 USLs with torsion and 44 USLs without torsion. Two radiologists evaluated the CT features, which consisted of poor contrast enhancement inside the USL, thin rim enhancement around the USL, calcification within the USL, a beak sign between the uterus and USL, fan-shaped poor contrast enhancement in the uterus area adjacent to the USL (dark fan sign), and ascites...
December 9, 2017: Japanese Journal of Radiology
https://www.readbyqxmd.com/read/29215949/laparoscopic-retroperitoneal-lymph-node-dissection-as-a-safe-procedure-for-postchemotherapy-residual-mass-in-testicular-cancer
#11
Eliney Ferreira Faria, Hugo Silva Neves, Breno Dauster, Roberto Dias Machado, Wesley Justino Magnabosco, Roberto Lodeiro Muller, Alexandre César Santos, Marcos Tobias-Machado
BACKGROUND: To evaluate the feasibility, clinical and perioperative outcomes of laparoscopic retroperitoneal lymph node dissection (L-RPLND) in the management of patients with germ cell tumors (GCT) and residual post-chemotherapy mass. METHODS: We report our experience of 25 patients treated with L-RPLND between 2008 and 2015. All 25 patients were diagnosed with GCT by primary pathological evaluation of the specimens after orchiectomy. All patients received cisplatin-based chemotherapy...
December 7, 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/29205553/vitronectin-vn-glycosylation-patterned-by-lectin-affinity-assays-a-potent-glycoproteomic-tool-to-discriminate-plasma-vn-from-cancer-ascites-vn
#12
H Benachour, J Leroy-Dudal, R Agniel, J Wilson, M Briand, F Carreiras, O Gallet
Changes in glycosylation have been associated with human cancer, but their complexity poses an analytical challenge. Ovarian cancer is a major cause of death in women because of an often late diagnosis. At least one-third of patients presents ascites fluid at diagnosis, and almost all have ascites at recurrence. Vitronectin (Vn) is a multifunctional glycoprotein that is suggested to be implicated in ovarian cancer metastasis and is found within ascites. The present study evaluated the potential of using lectin affinity for characterizing the glycosylation pattern of Vn...
December 4, 2017: Journal of Molecular Recognition: JMR
https://www.readbyqxmd.com/read/29201764/predictive-value-of-mean-platelet-volume-in-variceal-bleeding-due-to-cirrhotic-portal-hypertension
#13
Mehmet A Erdogan, Ali R Benli, Serap B Acmali, Mustafa Koroglu, Yahya Atayan, Ahmet Danalioglu, Burcak Kayhan
Aim: To investigate whether mean platelet volume (MPV) is a predictor of variceal bleeding in patients with cirrhotic portal hypertension. Materials and methods: This prospective cohort was performed in the internal medicine department of our tertiary care center. Cirrhotic patients were allocated into two groups: Group I consisted of 31 cases without a history of variceal bleeding, whereas group II was made up of 31 patients with a history of variceal bleeding...
January 2017: Euroasian Journal of Hepato-Gastroenterology
https://www.readbyqxmd.com/read/29188552/intrahepatic-subcapsular-biloma-after-endoscopic-retrograde-cholangiopancreatography-treated-by-endoscopic-biliary-drainage
#14
Hiroaki Igarashi, Hiroko Yamashita, Kiyoshi Tsuchiya, Dai Sugimoto, Itsuro Ogata
Several major complications from endoscopic retrograde cholangiopancreatography (ERCP), including pancreatitis, cholangitis, and hemorrhage have been discussed in detail; however, a few uncommon but severe complications have been reported. We encountered an unusual case of post-ERCP intrahepatic subcapsular biloma. An 89-year-old woman with a 25-mm mass located at the hepatic hilum, suggestive of cholangiocarcinoma, underwent ERCP which demonstrated complete stricture of the common hepatic duct. Subsequently, two plastic stents were placed from the common bile duct to the right and left intrahepatic branches...
November 29, 2017: Clinical Journal of Gastroenterology
https://www.readbyqxmd.com/read/29174555/predictive-modeling-for-determination-of-microscopic-residual-disease-at-primary-cytoreduction-an-nrg-oncology-gynecologic-oncology-group-182-study
#15
Neil S Horowitz, G Larry Maxwell, Austin Miller, Chad A Hamilton, Bunja Rungruang, Noah Rodriguez, Scott D Richard, Thomas C Krivak, Jeffrey M Fowler, David G Mutch, Linda Van Le, Roger B Lee, Peter Argenta, David Bender, Krishnansu S Tewari, David Gershenson, James J Java, Michael A Bookman
OBJECTIVE: Microscopic residual disease following complete cytoreduction (R0) is associated with a significant survival benefit for patients with advanced epithelial ovarian cancer (EOC). Our objective was to develop a prediction model for R0 to support surgeons in their clinical care decisions. METHODS: Demographic, pathologic, surgical, and CA125 data were collected from GOG 182 records. Patients enrolled prior to September 1, 2003 were used for the training model while those enrolled after constituted the validation data set...
January 2018: Gynecologic Oncology
https://www.readbyqxmd.com/read/29149171/risk-factors-for-hospitalizations-among-patients-with-cirrhosis-a-prospective-cohort-study
#16
Shari S Rogal, Viyan Udawatta, Imo Akpan, Akshata Moghe, Alexis Chidi, Amit Shetty, Eva Szigethy, Klaus Bielefeldt, Andrea DiMartini
This study was designed to assess unique baseline factors associated with subsequent hospitalizations in a cohort of outpatients with cirrhosis. A cohort of 193 patients with cirrhosis was recruited from an outpatient liver disease clinic at a single, tertiary medical center. Comorbidities, prescription medications, liver disease symptoms and severity, and psychiatric and pain symptoms were assessed at baseline using validated instruments. Inflammatory markers were measured using standardized Luminex assays...
2017: PloS One
https://www.readbyqxmd.com/read/29145776/role-of-computed-tomography-of-abdomen-in-difficult-to-diagnose-typhoid-fever-a-case-series
#17
Wajid Hafeez, S Rajalakshmi, S Sripriya, M Madhu Bashini
Background and Aim Diagnosis of typhoid is challenging when blood cultures fail to isolate Salmonella species. We report our experience with interpreting computed tomography (CT) abdomen findings in a case series of typhoid fever. Methods The case series consisted of patients who had a CT abdomen done as part of their investigations and a final diagnosis of typhoid fever. The CT films were reviewed and findings evaluated for distinctive features. Results During 2011-2017, 11 patients met the inclusion criteria...
January 1, 2017: Tropical Doctor
https://www.readbyqxmd.com/read/29128544/experimental-poisoning-by-vernonia-rubricaulis-in-sheep
#18
Kelly C S Godoy, Paula V Leal, Marcelo A Araújo, Alda I Souza, Arnildo Pott, Stephen T Lee, Claudio S L Barros, Ricardo A A de Lemos
In order to evaluate the susceptibility of sheep to V. rubricaulis and to establish the clinical signs, serum biochemistry, and pathological findings, eight sheep were fed varying doses of V. rubricaulis. The onset of clinical signs occurred 6-48 h after the ingestion of V. rubricaulis. Clinical courses lasted 6-56 h after the ingestion of the plant. Serum activities of aspartate aminotransferase, gamma-glutamyl transferase, and alkaline phosphatase were highly elevated and glucose blood levels were low in affected sheep...
November 8, 2017: Toxicon: Official Journal of the International Society on Toxinology
https://www.readbyqxmd.com/read/29128106/who-are-the-long-term-survivors-of-high-grade-serous-ovarian-cancer
#19
REVIEW
Claire Hoppenot, Mark A Eckert, Samantha M Tienda, Ernst Lengyel
Although the median survival for epithelial ovarian cancer (EOC) is <5years, approximately 15% of patients will survive for >10years. A better understanding of these exceptional responders could reveal opportunities to improve the dismal prognosis of most EOC patients. In this review, we examine the clinical and genomic features that have been associated with long-term survival, which is generally defined as survival of >7-10years after initial diagnosis. Clinical features influencing long-term survival have been best reported in large retrospective population-based studies...
November 8, 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/29113006/transjugular-portal-vein-recanalization-with-creation-of-intrahepatic-portosystemic-shunt-pvr-tips-in-patients-with-chronic-non-cirrhotic-non-malignant-portal-vein-thrombosis
#20
Christoph Klinger, Bettina Riecken, Arthur Schmidt, Andrea De Gottardi, Benjamin Meier, Jaime Bosch, Karel Caca
Purpose To determine safety and efficacy of transjugular portal vein recanalization with creation of intrahepatic portosystemic shunt (PVR-TIPS) in patients with chronic non-cirrhotic, non-malignant portal vein thrombosis (PVT). Methods This retrospective study includes 17 consecutive patients with chronic non-cirrhotic PVT (cavernous transformation n = 15). PVR-TIPS was indicated because of variceal bleeding (n = 13), refractory ascites (n = 2), portal biliopathy with recurrent cholangitis (n = 1), or abdominal pain (n = 1)...
November 7, 2017: Zeitschrift Für Gastroenterologie
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