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https://www.readbyqxmd.com/read/28231615/what-do-older-people-experiencing-loneliness-think-about-primary-care-or-community-based-interventions-to-reduce-loneliness-a-qualitative-study-in-england
#1
Kalpa Kharicha, Steve Iliffe, Jill Manthorpe, Carolyn A Chew-Graham, Mima Cattan, Claire Goodman, Maggie Kirby-Barr, Janet H Whitehouse, Kate Walters
Loneliness in later life is a common problem with poor health outcomes. However, interventions to prevent or ameliorate loneliness have a weak evidence base. The views of older people experiencing or at risk of loneliness in the community are important in identifying features of potential support, but have been little studied. Twenty-eight community dwelling people, aged 65 and over who reported being 'lonely much of the time' or identified as lonely from the de Jong Gierveld six-item loneliness scale in a larger study, participated in in-depth interviews, between June 2013 and May 2014...
February 23, 2017: Health & Social Care in the Community
https://www.readbyqxmd.com/read/28231514/the-social-and-economic-impact-of-biofortification-through-genetic-modification
#2
REVIEW
Hans De Steur, Matty Demont, Xavier Gellynck, Alexander J Stein
Genetic modification (GM) has been advocated as an alternative or complement to micronutrient interventions such as supplementation, fortification or dietary diversification. While proof-of-concept of various GM biofortified crops looks promising, the decision tree of policy makers is much more complex, and requires insight on their socio-economic impacts: Will it actually work? Is it financially sound? Will people accept it? Can it be implemented in a globalized world? This review shows that GM biofortification could effectively reduce the burden of micronutrient deficiencies, in an economically viable way, and is generally well received by target beneficiaries, despite some resistance and uncertainty...
February 20, 2017: Current Opinion in Biotechnology
https://www.readbyqxmd.com/read/28231496/attrition-in-trials-evaluating-complex-interventions-for-schizophrenia-systematic-review-and-meta-analysis
#3
REVIEW
P Szymczynska, S Walsh, L Greenberg, S Priebe
Essential criteria for the methodological quality and validity of randomized controlled trials are the drop-out rates from both the experimental intervention and the study as a whole. This systematic review and meta-analysis assessed these drop-out rates in non-pharmacological schizophrenia trials. A systematic literature search was used to identify relevant trials with ≥100 sample size and to extract the drop-out data. The rates of drop-out from the experimental intervention and study were calculated with meta-analysis of proportions...
February 11, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/28231044/original-research-paper-switching-antipsychotics-results-of-16-month-non-interventional-prospective-observational-clinical-research-of-inpatients-with-schizophrenia-spectrum-disorders
#4
Cvetka Bačar Bole, Mitja Pišlar, Metka Šen, Rok Tavčar, Aleš Mrhar
The study aims to identify prescribing and switching patterns of antipsychotics in clinical practice. A 16-month, prospective study was conducted at the Psychiatric Hospital Idrija, Slovenia. Inpatients (N = 311) with schizophrenia spectrum disorders were observed. The causes for switching antipsychotics and switching strategies were analyzed. Analyzing a total of 3954 prescriptions, the collected data confirmed that treatment strategies in this psychiatric hospital are very complex. It was found that 37 percent of inpatients had at least one switch...
March 1, 2017: Acta Pharmaceutica
https://www.readbyqxmd.com/read/28230899/shared-care-across-the-interface-between-primary-and-specialty-care-in-management-of-long-term-conditions
#5
REVIEW
Susan M Smith, Gráinne Cousins, Barbara Clyne, Shane Allwright, Tom O'Dowd
BACKGROUND: Shared care has been used in the management of many chronic conditions with the assumption that it delivers better care than primary or specialty care alone; however, little is known about the effectiveness of shared care. OBJECTIVES: To determine the effectiveness of shared care health service interventions designed to improve the management of chronic disease across the primary/specialty care interface. This is an update of a previously published review...
February 23, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28230061/neurofibromatosis-type-1
#6
REVIEW
David H Gutmann, Rosalie E Ferner, Robert H Listernick, Bruce R Korf, Pamela L Wolters, Kimberly J Johnson
Neurofibromatosis type 1 is a complex autosomal dominant disorder caused by germline mutations in the NF1 tumour suppressor gene. Nearly all individuals with neurofibromatosis type 1 develop pigmentary lesions (café-au-lait macules, skinfold freckling and Lisch nodules) and dermal neurofibromas. Some individuals develop skeletal abnormalities (scoliosis, tibial pseudarthrosis and orbital dysplasia), brain tumours (optic pathway gliomas and glioblastoma), peripheral nerve tumours (spinal neurofibromas, plexiform neurofibromas and malignant peripheral nerve sheath tumours), learning disabilities, attention deficits, and social and behavioural problems, which can negatively affect quality of life...
February 23, 2017: Nature Reviews. Disease Primers
https://www.readbyqxmd.com/read/28229986/executive-function-training-for-children-with-attention-deficit-hyperactivity-disorder
#7
Lan Shuai, David Daley, Yu-Feng Wang, Jin-Song Zhang, Yan-Ting Kong, Xin Tan, Ning Ji
BACKGROUND: Accumulating evidence indicates that attention deficit hyperactivity disorder (ADHD) is associated with core deficits in executive function (EF) which predicts poorer academic and occupational functioning. This makes early intervention targeting EF impairments important to prevent long-term negative outcomes. Cognitive training is a potential ADHD treatment target. The present study aimed to explore the efficacy, feasibility, and acceptability of a cognitive training program (targeting child's multiple EF components and involving parent support in daily life), as a nonpharmacological intervention for children with ADHD...
2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28229541/psychological-and-neural-contributions-to-appetite-self-regulation
#8
Luke E Stoeckel, Leann L Birch, Todd Heatherton, Traci Mann, Christine Hunter, Susan Czajkowski, Lisa Onken, Paige K Berger, Cary R Savage
OBJECTIVE: This paper reviews the state of the science on psychological and neural contributions to appetite self-regulation in the context of obesity. METHODS: Three content areas (neural systems and cognitive functions; parenting and early childhood development; and goal setting and goal striving) served to illustrate different perspectives on the psychological and neural factors that contribute to appetite dysregulation in the context of obesity. Talks were initially delivered at an NIH workshop consisting of experts in these three content areas, and then content areas were further developed through a review of the literature...
March 2017: Obesity
https://www.readbyqxmd.com/read/28229396/statistical-approaches-to-longitudinal-data-analysis-in-neurodegenerative-diseases-huntington-s-disease-as-a-model
#9
REVIEW
Tanya P Garcia, Karen Marder
Understanding the overall progression of neurodegenerative diseases is critical to the timing of therapeutic interventions and design of effective clinical trials. Disease progression can be assessed with longitudinal study designs in which outcomes are measured repeatedly over time and are assessed with respect to risk factors, either measured repeatedly or at baseline. Longitudinal data allows researchers to assess temporal disease aspects, but the analysis is complicated by complex correlation structures, irregularly spaced visits, missing data, and mixtures of time-varying and static covariate effects...
February 2017: Current Neurology and Neuroscience Reports
https://www.readbyqxmd.com/read/28229314/understanding-etiology-of-hearing-loss-as-a-contributor-to-language-dysfluency-and-its-impact-on-assessment-and-treatment-of-people-who-are-deaf-in-mental-health-settings
#10
Charlene J Crump, Stephen H Hamerdinger
Working with individuals who are deaf in mental health settings can be complex work, necessitating consideration for the difference in language abilities. These differences include not only the language differences of American Sign Language (ASL) and English, but also the range of heterogeneity within the Deaf Community. Multiple influences such as mental illness, medical conditions, language deprivation and the etiology of deafness can impact how a person acquires and uses language. This article will discuss how various causes of deafness create the potential for specific language dysfluencies with individuals who are deaf in mental health settings...
February 22, 2017: Community Mental Health Journal
https://www.readbyqxmd.com/read/28228292/a-fresh-look-at-bioresorbable-scaffold-technology-intuition-pumps
#11
EDITORIAL
Sundeep Mishra
Bioresorbable scaffolds (BRS) are a new enticing treatment option in coronary interventions. Absorb BVS™ Is the most widely used and researched polymer based BRS, eluting everolimus. However currently it has several technical limitations; low radial support, larger strut size, poor visualization, poor deliverability and complex implantation technique. Magnesium based BRS are an alternate but they are also limited not only by lower radial support and poor visualization but also earlier bio-absorption. Material processing: blow-molding, annealing, polymer orientation, change in composition and use of higher molecular weight polymer, as well new polymers like tyrosine or salicyclate analogs and even hybrid (polymer and metallic) combined with intelligent cell design has led to evolution of BRS technology...
January 2017: Indian Heart Journal
https://www.readbyqxmd.com/read/28228081/the-neurobiology-and-psychiatric-perspective-of-vaginismus-linking-the-pharmacological-and-psycho-social-interventions
#12
Zuri Shahidii Kadir, Hatta Sidi, Jaya Kumar, Srijit Das, Marhani Midin, Najwa Baharuddin
Vaginismus is an involuntary muscle contraction of the outer third of vaginal barrel causing sexual penetration almost impossible. It is generally classified under sexual pain disorder (SPD). In Diagnostic and Statistical Manual, 5th edition, it is classified under the new rubric of Genito-Pelvic Pain/Sexual Penetration Disorder. This fear-avoidance condition poses an ongoing significant challenge to the medical and health professionals due to the very demanding needs in health care despite its unpredictable prognosis...
February 22, 2017: Current Drug Targets
https://www.readbyqxmd.com/read/28228074/lenticulostriate-artery-and-lenticulostriate-artery-neural-complex-new-concept-for-intracerebral-hemorrhage
#13
Rong Hu, Hua Feng
BACKGROUND: Spontaneous intracerebral hemorrhage (ICH) is the poorest prognosis of all stroke subtypes with a high mortality and morbidity. Although considerable progress has been made, no intervention is currently available to alter the outcome of patients with ICH, suggesting a new concept directing ICH study is urgently needed. METHODS: Most ICH occurs in the deep area of the brain, the basal ganglion, whose blood supply is mainly from lenticulostriate arteries (LSAs)...
February 20, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/28227836/exerciser-for-rehabilitation-of-the-arm-era-development-and-unique-features-of-a-3d-end-effector-robot
#14
Marie-Helene Milot, Mathieu Hamel, Philippe-Olivier Provost, Julien Bernier-Ouellet, Maxime Dupuis, Dominic Letourneau, Simon Briere, Francois Michaud, Marie-Helene Milot, Mathieu Hamel, Philippe-Olivier Provost, Julien Bernier-Ouellet, Maxime Dupuis, Dominic Letourneau, Simon Briere, Francois Michaud, Philippe-Olivier Provost, Dominic Letourneau, Maxime Dupuis, Marie-Helene Milot, Francois Michaud, Mathieu Hamel, Julien Bernier-Ouellet, Simon Briere
Stroke is one of the leading causes of disability worldwide. Consequently, many stroke survivors exhibit difficulties undergoing voluntary movement in their affected upper limb, compromising their functional performance and level of independence. To minimize the negative impact of stroke disabilities, exercises are recognized as a key element in post-stroke rehabilitation. In order to provide the practice of exercises in a uniform and controlled manner as well as increasing the efficiency of therapists' interventions, robotic training has been found, and continues to prove itself, as an innovative intervention for post-stroke rehabilitation...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227689/robotic-system-with-multiplex-power-transmission-for-mri-guided-percutaneous-interventions
#15
Yang Wang, Sungmin Kim, Everette C Burdette, Peter Kazanzides, Iulian Iordachita, Yang Wang, Sungmin Kim, Everette C Burdette, Peter Kazanzides, Iulian Iordachita, Sungmin Kim, Peter Kazanzides, Everette C Burdette, Iulian Iordachita, Yang Wang
In minimally invasive prostate percutaneous interventions, Magnetic Resonance Imaging (MRI) compatible robotic assistive systems developed over the years tend to have multiple degrees of freedom (DOF) to accomplish complex surgical tasks. This paper presents a novel design of an MRI-compatible transmission that allows one driving motor to control a multiplexed DOF robot system. The transmission could reduce the number of motors in the system, while maintaining the functionality of the system, by controlling each motion sequentially rather than simultaneously...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227260/automated-detection-of-atrial-fibrillation-episode-using-novel-heart-rate-variability-features
#16
Mehrin Gilani, J Mikael Eklund, Masoud Makrehchi, Mehrin Gilani, J Mikael Eklund, Masoud Makrehchi, J Mikael Eklund, Masoud Makrehchi, Mehrin Gilani
Atrial fibrillation (AF) is one of the most common life-threatening arrhythmia affecting around six million adults in the US. Typical detection of AF requires tedious and manual analysis of ECG which can often delay medical intervention. With the advent of wearable devices that can accurately record the time interval between two heartbeats (RR interval), automated and timely detection of AF is now possible. In this paper, we engineer novel heart rate variability features based on linear and non-linear dynamics of RR intervals...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227046/design-and-development-of-an-aac-app-based-on-a-speech-to-symbol-technology
#17
Elena Radici, Stefano Bonacina, Gianluca De Leo, Elena Radici, Stefano Bonacina, Gianluca De Leo, Gianluca De Leo, Stefano Bonacina, Elena Radici
The purpose of this paper is to present the design and the development of an Augmentative and Alternative Communication app that uses a speech to symbol technology to model language, i.e. to recognize the speech and display the text or the graphic content related to it. Our app is intended to be adopted by communication partners who want to engage in interventions focused on improving communication skills. Our app has the goal of translating simple speech sentences in a set of symbols that are understandable by children with complex communication needs...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226726/guide-wire-detecting-using-a-modified-cascade-classifier-in-interventional-radiology
#18
Li Wang, Xiao-Liang Xie, Zhan-Jie Gao, Gui-Bin Bian, Zeng-Guang Hou, Li Wang, Xiao-Liang Xie, Zhan-Jie Gao, Gui-Bin Bian, Zeng-Guang Hou
Endovascular surgery is becoming a widespread procedure to treat cardiovascular diseases (CVDs) such as abdominal aortic aneurysm and peripheral artery disease. The guide-wire is a crucial surgical instrument inserted into vessels to offer guidance to physicians during the surgery. There are some approaches for tracking the guide-wire, most algorithms consist of two phases, namely, the initialization phase and the tracking phase. In the initialization phase, most algorithms use B-splines for modeling the guide-wire which requires manually annotated data...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226723/improving-assessment-of-congenital-heart-disease-through-rapid-patient-specific-modeling
#19
Kathleen Gilbert, Genevieve Farrar, Brett Cowan, Avan Suinesiaputra, Christopher Occleshaw, Beau Pontre, James Perry, Sanjeet Hegde, Jeffrey Omens, Andrew McCulloch, Alistair Young, Kathleen Gilbert, Genevieve Farrar, Brett Cowan, Avan Suinesiaputra, Christopher Occleshaw, Beau Pontre, James Perry, Sanjeet Hegde, Jeffrey Omens, Andrew McCulloch, Alistair Young, James Perry, Genevieve Farrar, Avan Suinesiaputra, Brett Cowan, Kathleen Gilbert, Jeffrey Omens, Christopher Occleshaw, Sanjeet Hegde, Beau Pontre, Andrew McCulloch, Alistair Young
Congenital heart disease is the most common birth defect, with an incidence of 75 in every 1000 births. As a result of improved interventions, 90% of people with congenital heart disease now survive to adulthood. They must undergo regular imaging to assess their biventricular (left and right ventricular) function. Analysis of the images is problematic due to the large variety of shapes and complex geometry. In this paper we extend a biventricular modeling method to improve the analysis of MR images from congenital heart disease patients...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226711/computer-aided-planning-and-reconstruction-of-cranial-3d-implants
#20
Markus Gall, Xing Li, Xiaojun Chen, Dieter Schmalstieg, Jan Egger, Markus Gall, Xing Li, Xiaojun Chen, Dieter Schmalstieg, Jan Egger, Jan Egger, Markus Gall, Xing Li, Dieter Schmalstieg, Xiaojun Chen
In this contribution, a prototype for semiautomatic computer-aided planning and reconstruction of cranial 3D Implants is presented. The software prototype guides the user through the workflow, beginning with loading and mirroring the patient's head to obtain an initial curvature of the cranial implant. However, naïve mirroring is not sufficient for an implant, because human heads are in general too asymmetric. Thus, the user can perform Laplacian smoothing, followed by Delaunay triangulation, for generating an aesthetic looking and well-fitting implant...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
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