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https://www.readbyqxmd.com/read/29793001/health-literacy-in-chronic-disease-management-a-matter-of-interaction
#1
Iris van der Heide, Iraj Poureslami, Wayne Mitic, Jessica Shum, Irving Rootman, J Mark FitzGerald
Health literacy plays a crucial role in chronic disease management. To comprehensively manage chronic conditions on a daily basis, individuals must be able to assess, understand, evaluate and use health information. Several key publications emphasise that health literacy is not merely a matter of individual skills, but that it is highly dependent on the accessibility of healthcare systems, the communication skills of healthcare professionals, and the level of complexity of health information. However, the literature indicates that health literacy is mainly framed and measured as an individual attribute in research...
May 21, 2018: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/29792462/extreme-teams-toward-a-greater-understanding-of-multiagency-teamwork-during-major-emergencies-and-disasters
#2
Nicola Power
Major emergencies are extreme team decision making environments. They are complex, dynamic, high-stakes and fast paced events, wherein successful resolution is contingent upon effective teamwork. Not only do emergency teams coordinate at the intrateam level (e.g., police team), but they are increasingly required to operate at the interteam level (e.g., police, fire and ambulance teams). This is in response to the desire for networked and cost-effective practice and due to the evolving nature of modern threats, such as extreme weather events and terrorist attacks, which require a multi- rather than single-agency response...
May 2018: American Psychologist
https://www.readbyqxmd.com/read/29792459/teamwork-in-healthcare-key-discoveries-enabling-safer-high-quality-care
#3
Michael A Rosen, Deborah DiazGranados, Aaron S Dietz, Lauren E Benishek, David Thompson, Peter J Pronovost, Sallie J Weaver
Few industries match the scale of health care. In the United States alone, an estimated 85% of the population has at least 1 health care encounter annually and at least one quarter of these people experience 4 to 9 encounters annually. A single visit requires collaboration among a multidisciplinary group of clinicians, administrative staff, patients, and their loved ones. Multiple visits often occur across different clinicians working in different organizations. Ineffective care coordination and the underlying suboptimal teamwork processes are a public health issue...
May 2018: American Psychologist
https://www.readbyqxmd.com/read/29792243/understanding-the-science-of-portion-control-and-the-art-of-downsizing
#4
Marion M Hetherington, Pam Blundell-Birtill, Samantha J Caton, Joanne E Cecil, Charlotte E Evans, Barbara J Rolls, Tang Tang
Offering large portions of high-energy-dense (HED) foods increases overall intake in children and adults. This is known as the portion size effect (PSE). It is robust, reliable and enduring. Over time, the PSE may facilitate overeating and ultimately positive energy balance. Therefore, it is important to understand what drives the PSE and what might be done to counter the effects of an environment promoting large portions, especially in children. Explanations for the PSE are many and diverse, ranging from consumer error in estimating portion size to simple heuristics such as cleaning the plate or eating in accordance with consumption norms...
May 24, 2018: Proceedings of the Nutrition Society
https://www.readbyqxmd.com/read/29792224/health-technology-assessment-of-public-health-interventions-an-analysis-of-characteristics-and-comparison-of-methods-study-protocol
#5
Tim Mathes, Gerald Willms, Stephanie Polus, Constance Stegbauer, Melanie Messer, Corinna Klingler, Heidi Ehrenreich, Dea Niebuhr, Georg Marckmann, Ansgar Gerhardus, Dawid Pieper
BACKGROUND: Conducting a health technology assessment (HTA) of public health interventions (PHIs) poses some challenges. PHIs are often complex interventions, which affect the number and degree of interactions of the aspects to be assessed. Randomized controlled trials on PHIs are rare as they are difficult to conduct because of ethical or feasibility issues. The aim of this study is to provide an overview of the methodological characteristics and to compare the applied assessment methods in HTAs on PHIs...
May 23, 2018: Systematic Reviews
https://www.readbyqxmd.com/read/29791911/improving-translation-from-preclinical-studies-to-clinical-trials-in-acute-kidney-injury
#6
Marco Fiorentino, John A Kellum
BACKGROUND: Several cellular and molecular targets and mechanisms have been investigated in preclinical studies of acute kidney injury (AKI), but translation in successful clinical studies has failed to date. This article reviews many issues that have limited this and the potential future perspectives in AKI prevention and treatment. SUMMARY: Preclinical models of AKI should closely mimic the complexity of human AKI, considering the importance of several comorbidities in determining the clinical course and outcomes in the human disease...
May 23, 2018: Nephron
https://www.readbyqxmd.com/read/29791741/diffusing-and-scaling-evidence-based-interventions-eight-lessons-for-early-child-development-from-the-implementation-of-perinatal-home-visiting-in-south-africa
#7
Mark Tomlinson, Xanthe Hunt, Mary Jane Rotheram-Borus
Most low- and middle-income countries lack resources with which to implement public health programs. As such, there is a necessity to facilitate programing that judiciously makes use of what resources there are. However, despite evidence for the efficacy of many interventions, translating these into real-world effectiveness, and then into scalability, is complex and has often been neglected. We draw on a case study of Philani+ (a maternal and child health intervention implemented in South Africa) to distil eight features of health programing that aid intervention effectiveness...
May 2018: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/29791610/what-do-cochrane-systematic-reviews-say-about-cardiac-arrest-management
#8
Rafael Leite Pacheco, Juliana Trevizo, Caio Augusto de Souza, Gabriel Alves, Bruno Sakaya, Luciana Thiago, Aécio Flávio Teixeira de Góis, Rachel Riera
CONTEXT AND OBJECTIVE: Cardiac arrest is associated with high morbidity and mortality and imposes a significant burden on the healthcare system. Management of cardiac arrest patients is complex and involves approaches with multiple interventions. Here, we aimed to summarize the available evidence regarding the interventions used in cardiac arrest cases. DESIGN AND SETTING: Review of systematic reviews (SRs), conducted in the Discipline of Evidence-Based Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo...
March 2018: São Paulo Medical Journal, Revista Paulista de Medicina
https://www.readbyqxmd.com/read/29791570/osteoradionecrosis-of-the-jaws-case-series-treated-with-adjuvant-low-level-laser-therapy-and-antimicrobial-photodynamic-therapy
#9
Guilherme Henrique Ribeiro, Mariana Comparotto Minamisako, Inês Beatriz da Silva Rath, Aira Maria Bonfim Santos, Alyne Simões, Keila Cristina Rausch Pereira, Liliane Janete Grando
BACKGROUND: Osteoradionecrosis of the jaw (ORNJ) is the most severe and complex sequel of head and neck radiotherapy (RT) because of the bone involved, it may cause pain, paresthesia, foul odor, fistulae with suppuration, need for extra oral communication and pathological fracture. We treated twenty lesions of ORNJ using low-level laser therapy (LLLT) and antimicrobial photodynamic therapy (aPDT). The objective of this study was to stimulate the affected area to homeostasis and to promote the healing of the oral mucosa...
2018: Journal of Applied Oral Science: Revista FOB
https://www.readbyqxmd.com/read/29791025/factors-associated-with-quality-of-life-of-dementia-caregivers-direct-and-indirect-effects
#10
Hikaru Oba, Teruyuki Matsuoka, Yuka Kato, Jin Narumoto
AIMS: To examine the direct and indirect relationships between the characteristics of patients and caregivers associated with caregivers' quality of life. BACKGROUND: Complex relationships exist among the factors associated with caregivers' quality of life. DESIGN: This study was a retrospective cross-sectional design. METHODS: The data were retrospectively extracted from participants who had visited the Center for Diagnosis of Dementia at Kyoto Prefectural University of Medicine from April 2013 - March 2016...
May 23, 2018: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/29790727/pathophysiology-of-severe-traumatic-brain-injury-overview
#11
Ruth A O'leary, Alistair D Nichol
Traumatic brain injury is a leading cause of morbidity and mortality globally, particularly among young people, with significant social and economic effects. The World Health Organization (WHO) estimates that more than five million people die each year from traumatic injuries worldwide. While public health initiative such as seatbelts and airbags have had a major impact, it will be impossible to prevent traumatic brain injury, it is therefore that we understand the pathophysiology of secondary brain injury to be able to effectively treat our patient but aloes to develop novel targets of future interventions...
May 22, 2018: Journal of Neurosurgical Sciences
https://www.readbyqxmd.com/read/29790460/establishment-of-the-european-meningococcal-strain-collection-genome-library-emsc-gl-for-the-2011-to-2012-epidemiological-year
#12
Holly B Bratcher, Carina Brehony, Sigrid Heuberger, Despo Pieridou-Bagatzouni, Pavla Křížová, Steen Hoffmann, Maija Toropainen, Muhamed-Kheir Taha, Heike Claus, Georgina Tzanakaki, Tímea Erdôsi, Jelena Galajeva, Arie van der Ende, Anna Skoczyńska, Marina Pana, Alena Vaculíková, Metka Paragi, Martin Cj Maiden, Dominique A Caugant
Invasive meningococcal disease surveillance in Europe combines isolate characterisation and epidemiological data to support public health intervention. A representative European Meningococcal Strain Collection (EMSC) of IMD isolates was obtained, and whole genome sequenced to characterise 799 EMSC isolates from the epidemiological year July 2011-June 2012. To establish a genome library (GL), the isolate information was deposited in the pubMLST.org/neisseria database. Genomes were curated and annotated at 2,429 meningococcal loci, including those defining clonal complex, capsule, antigens, and antimicrobial resistance...
May 2018: Euro Surveillance: Bulletin Européen sur les Maladies Transmissibles, European Communicable Disease Bulletin
https://www.readbyqxmd.com/read/29790133/-spiritual-care-for-patients-and-their-families-in-the-intensive-care-unit
#13
Hsing-Yu Yang
To date, most of the literature in Taiwan on clinical spiritual care has focused either on improving the spiritual well-being of patients or on developing assessment tools suitable for use with end-stage cancer patients. Few articles have discussed spiritual care in the context of intensive care unit (ICU) patients and their family members. When ICU patients face life-threatening and complex physiological problems, spiritual care plays an important role in disease recovery and adaptation and impacts the satisfaction and medical decision-making of critical patients and their family members...
June 2018: Hu Li za Zhi the Journal of Nursing
https://www.readbyqxmd.com/read/29790125/management-of-major-bleeding-and-outcomes-in-patients-treated-with-direct-oral-anticoagulants-results-from-the-start-event-registry
#14
Sophie Testa, Walter Ageno, Emilia Antonucci, Rossella Morandini, Jan Beyer-Westendorf, Maurizio Paciaroni, Marc Righini, Piera Sivera, Peter Verhamme, Vittorio Pengo, Daniela Poli, Gualtiero Palareti
The management of major bleeding in patients treated with direct oral anticoagulants (DOACs) is still not well established. START-Events, a branch of the START registry (Survey on anTicoagulated pAtients RegisTer) (NCT02219984), aims to describe the actual management of bleeding or recurrent thrombotic events in routine clinical practice. We here present the results of the management of bleeding patients. The START-Event registry is a prospective, observational, multicenter, international study. Baseline characteristics (demographic, clinical, risk factors) of patients, laboratory data at admission and during follow-up, site of bleeding, therapeutic strategies, and outcomes at the time of hospital discharge and after 6 months were recorded on a web-based case report form...
May 22, 2018: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/29789665/existing-and-novel-biomarkers-for-precision-medicine-in-systemic-sclerosis
#15
REVIEW
Peter J Wermuth, Sonsoles Piera-Velazquez, Joel Rosenbloom, Sergio A Jimenez
The discovery and validation of biomarkers resulting from technological advances in the analysis of genomic, transcriptomic, lipidomic and metabolomic pathways involved in the pathogenesis of complex human diseases have led to the development of personalized and rationally designed approaches for the clinical management of such disorders. Although some of these approaches have been applied to systemic sclerosis (SSc), an unmet need remains for validated, non-invasive biomarkers to aid in the diagnosis of SSc, as well as in the assessment of disease progression and response to therapeutic interventions...
May 22, 2018: Nature Reviews. Rheumatology
https://www.readbyqxmd.com/read/29789467/the-present-and-future-of-whole-genome-sequencing-wgs-and-whole-metagenome-sequencing-wms-for-surveillance-of-antimicrobial-resistant-microorganisms-and-antimicrobial-resistance-genes-across-the-food-chain
#16
REVIEW
Elena A Oniciuc, Eleni Likotrafiti, Adrián Alvarez-Molina, Miguel Prieto, Jesús A Santos, Avelino Alvarez-Ordóñez
Antimicrobial resistance (AMR) surveillance is a critical step within risk assessment schemes, as it is the basis for informing global strategies, monitoring the effectiveness of public health interventions, and detecting new trends and emerging threats linked to food. Surveillance of AMR is currently based on the isolation of indicator microorganisms and the phenotypic characterization of clinical, environmental and food strains isolated. However, this approach provides very limited information on the mechanisms driving AMR or on the presence or spread of AMR genes throughout the food chain...
May 22, 2018: Genes
https://www.readbyqxmd.com/read/29789411/heliox-adjunct-therapy-for-neonates-with-congenital-diaphragmatic-hernia
#17
Audra C Wise, Mallory A Boutin, Ellen M Knodel, James A Proudfoot, Brian P Lane, Marva L Evans, Denise M Suttner, Amy L Kimball
BACKGROUND: Congenital diaphragmatic hernia remains a complex disease with significant morbidity and mortality. Hypercarbia is a common derangement in this population, which often requires escalating ventilator support. By decreasing airway turbulence and enhancing CO2 removal, inhaled helium-oxygen mixture (heliox) has the potential to improve ventilation and thereby decrease ventilator support and its associated lung injury. METHODS: Retrospective cohort review of all neonates with congenital diaphragmatic hernia treated at Rady Children's Hospital San Diego during 2011-2015...
May 22, 2018: Respiratory Care
https://www.readbyqxmd.com/read/29789022/healthcare-disparities-amongst-vulnerable-populations-of-arabs-and-jews-in-israel
#18
Efrat Shadmi
The complex nature of studying health and healthcare disparities in general, and in the context of the Israeli healthcare system in particular, is depicted in two recent IJHPR articles. The first examines Emergency Department (ED) waiting times in a tertiary children's hospital and the second examines disparities in the health care for people with schizophrenia of an ethnic-national minority. Contrary to other Israeli studies on wide disparities in health and healthcare, these studies show no disparities -  ED waiting times did not differ among Arab and Jewish children and report no differences in performance of Hemoglobin A1C tests or in surgical interventions in patients with cardiovascular disease between Arabs and Jews with schizophrenia...
May 22, 2018: Israel Journal of Health Policy Research
https://www.readbyqxmd.com/read/29788906/influences-on-the-adoption-of-patient-safety-innovation-in-primary-care-a-qualitative-exploration-of-staff-perspectives
#19
Ian Litchfield, Paramjit Gill, Tony Avery, Stephen Campbell, Katherine Perryman, Kate Marsden, Sheila Greenfield
BACKGROUND: Primary care is changing rapidly to meet the needs of an ageing and chronically ill population. New ways of working are called for yet the introduction of innovative service interventions is complicated by organisational challenges arising from its scale and diversity and the growing complexity of patients and their care. One such intervention is the multi-strand, single platform, Patient Safety Toolkit developed to help practices provide safer care in this dynamic and pressured environment where the likelihood of adverse incidents is increasing...
May 22, 2018: BMC Family Practice
https://www.readbyqxmd.com/read/29788870/small-molecules-as-drugs-to-upregulate-metastasis-suppressors-in-cancer-cells
#20
Ka Ming Wong, Jiaxing Song, Vasu Saini, Yung H Wong
It is well-recognized that the majority of cancer-related deaths are attributed to metastasis, which can arise from virtually any type of tumor. Metastasis is a complex multistep process wherein cancer cells must break away from the primary tumor, intravasate into the circulatory or lymphatic systems, extravasate, proliferate and eventually colonize secondary sites. Since these molecular processes involve the coordinated actions of numerous proteins, targeted disruptions of key players along these pathways represent possible therapeutic interventions to impede metastasis formation and reduce cancer mortality...
May 21, 2018: Current Medicinal Chemistry
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