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Cardiac mri lge

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https://www.readbyqxmd.com/read/29158437/cardiac-magnetic-resonance-imaging-in-myocarditis-reveals-persistent-disease-activity-despite-normalization-of-cardiac-enzymes-and-inflammatory-parameters-at-3-month-follow-up
#1
Jan Berg, Jan Kottwitz, Nora Baltensperger, Christine K Kissel, Marina Lovrinovic, Tarun Mehra, Frank Scherff, Christian Schmied, Christian Templin, Thomas F Lüscher, Bettina Heidecker, Robert Manka
BACKGROUND: There is a major unmet need to identify high-risk patients in myocarditis. Although decreasing cardiac and inflammatory markers are commonly interpreted as resolving myocarditis, this assumption has not been confirmed as of today. We sought to evaluate whether routine laboratory parameters at diagnosis predict dynamic of late gadolinium enhancement (LGE) as persistent LGE has been shown to be a risk marker in myocarditis. METHODS AND RESULTS: Myocarditis was diagnosed based on clinical presentation, high-sensitivity troponin T, and cardiac magnetic resonance imaging, after exclusion of obstructive coronary artery disease by angiography...
November 2017: Circulation. Heart Failure
https://www.readbyqxmd.com/read/29153657/cardiac-magnetic-resonance-imaging-in-myocardial-inflammation-in-autoimmune-rheumatic-diseases-an-appraisal-of-the-diagnostic-strengths-and-limitations-of-the-lake-louise-criteria
#2
Sophie Mavrogeni, Juerg Schwitter, Albert van Rossum, Robin Nijveldt, Antony Aletras, Genovefa Kolovou, Gerald Pohost, Joao Lima
Myocardial inflammation in autoimmune rheumatic diseases (ARDs) is the endpoint of various pathophysiologic processes. The Lake Louise-criteria is the most popular approach for the diagnosis of myocarditis. However, due to the diversity of myocardial inflammation in ARDs, some issues should be acknowledged. Of the three Lake Louise indices, early and late gadolinium enhancement (EGE and LGE respectively) measurements may be affected by co-existing disease processes or be present due to a fibrotic ARD like systemic sclerosis, leaving T2-ratio as the only uniformly robust measurement across ARDs...
November 14, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/29121086/improved-segmented-modified-look-locker-inversion-recovery-t1-mapping-sequence-in-mice
#3
Maryam Nezafat, Isabel T Ramos, Markus Henningsson, Andrea Protti, Tamer Basha, René M Botnar
OBJECT: To develop and evaluate a 2D modified Look-Locker (MOLLI) for high-resolution T1 mapping in mice using a 3T MRI scanner. MATERIALS AND METHODS: To allow high-resolution T1 mapping in mice at high heart rates a multi-shot ECG-triggered 2D MOLLI sequence was developed. In the proposed T1 mapping sequence the optimal number of sampling points and pause cardiac cycles following an initial adiabatic inversion pulse was investigated in a phantom. Seven native control and eight mice, 3 days post myocardial infarction (MI) after administration of gadolinium were scanned...
2017: PloS One
https://www.readbyqxmd.com/read/29114174/mr-assessment-of-acute-pathologic-process-after-myocardial-infarction-in-a-permanent-ligation-mouse-model-role-of-magnetic-nanoparticle-contrasted-mri
#4
Cheongsoo Park, Eun-Hye Park, Jongeun Kang, Javeria Zaheer, Hee Gu Lee, Chul-Ho Lee, Kiyuk Chang, Kwan Soo Hong
We evaluated the relationship between myocardial infarct size and inflammatory response using cardiac magnetic resonance imaging (CMR) in an acute myocardial infarction (AMI) mouse model. Myocardial infarction (MI) was induced in 14 mice by permanent ligation of the left anterior descending artery. Late gadolinium enhancement (LGE), manganese-enhanced MRI (MEMRI), and magnetofluorescent nanoparticle MRI (MNP-MRI) were performed 1, 2, and 3 days after MI, respectively. The size of the enhanced lesion was quantitatively determined using Otsu's thresholding method in area-based and sector-based approaches and was compared statistically...
2017: Contrast Media & Molecular Imaging
https://www.readbyqxmd.com/read/29104737/cardiac-magnetic-resonance-imaging-which-information-is-useful-for-the-arrhythmologist
#5
REVIEW
Elia De Maria, Annachiara Aldrovandi, Ambra Borghi, Letizia Modonesi, Stefano Cappelli
Cardiac magnetic resonance (CMR) is a non-invasive, non-ionizing, diagnostic technique that uses magnetic fields, radio waves and field gradients to generate images with high spatial and temporal resolution. After administration of contrast media (e.g., gadolinium chelate), it is also possible to acquire late images, which make possible the identification and quantification of myocardial areas with scar/fibrosis (late gadolinium enhancement, LGE). CMR is currently a useful instrument in clinical cardiovascular practice for the assessment of several pathological conditions, including ischemic and non-ischemic cardiomyopathies and congenital heart disease...
October 26, 2017: World Journal of Cardiology
https://www.readbyqxmd.com/read/29103621/appropriateness-of-anteroseptal-myocardial-infarction-nomenclature-evaluated-by-late-gadolinium-enhancement-cardiovascular-magnetic-resonance-imaging
#6
Joseph Allencherril, Yama Fakhri, Henrik Engblom, Einar Heiberg, Marcus Carlsson, Jean-Luc Dubois-Rande, Sigrun Halvorsen, Trygve S Hall, Alf-Inge Larsen, Svend Eggert Jensen, Hakan Arheden, Dan Atar, Peter Clemmensen, Dipan J Shah, Benjamin Cheong, Maria Sejersten, Yochai Birnbaum
BACKGROUND: In traditional literature, it appears that "anteroseptal" MIs with Q waves in V1-V3 involve basal anteroseptal segments although studies have questioned this belief. METHODS: We studied patients with first acute anterior Q-wave (>30ms) MI. All underwent late gadolinium enhancement (LGE) cardiac magnetic resonance imaging (MRI). RESULTS: Those with Q waves in V1-V2 (n=7) evidenced LGE >50% in 0%, 43%, 43%, 57%, and 29% of the basal anteroseptal, mid anteroseptal, apical anterior, apical septal segments, and apex, respectively...
October 6, 2017: Journal of Electrocardiology
https://www.readbyqxmd.com/read/29093431/increased-prognostic-value-of-query-amyloid-late-enhancement-score-in-light-chain-cardiac-amyloidosis
#7
Ke Wan, Jiayu Sun, Yuchi Han, Hong Liu, Dan Yang, Weihao Li, Jie Wang, Wei Cheng, Qing Zhang, Zhi Zeng, Yucheng Chen
BACKGROUND: Late gadolinium enhancement (LGE) pattern is a powerful imaging biomarker for prognosis of cardiac amyloidosis. It is unknown if the query amyloid late enhancement (QALE) score in light-chain (AL) amyloidosis could provide increased prognostic value compared with LGE pattern.Methods and Results:Seventy-eight consecutive patients with AL amyloidosis underwent contrast-enhanced cardiovascular magnetic resonance imaging. Patients with cardiac involvement were grouped by LGE pattern and analyzed using QALE score...
November 2, 2017: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/29076052/assessment-of-acute-myocarditis-by-cardiac-magnetic-resonance-imaging-comparison-of-qualitative-and-quantitative-analysis-methods
#8
Massimo Imbriaco, Carmela Nappi, Marta Puglia, Marco De Giorgi, Serena Dell'Aversana, Renato Cuocolo, Andrea Ponsiglione, Igino De Giorgi, Maria Vincenza Polito, Michele Klain, Federico Piscione, Leonardo Pace, Alberto Cuocolo
BACKGROUND: To compare cardiac magnetic resonance (CMR) qualitative and quantitative analysis methods for the noninvasive assessment of myocardial inflammation in patients with suspected acute myocarditis (AM). METHODS: A total of 61 patients with suspected AM underwent coronary angiography and CMR. Qualitative analysis was performed applying Lake-Louise Criteria (LLC), followed by quantitative analysis based on the evaluation of edema ratio (ER) and global relative enhancement (RE)...
October 26, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/29069369/high-resolution-three-dimensional-late-gadolinium-enhanced-cardiac-magnetic-resonance-imaging-to-identify-the-underlying-substrate-of-ventricular-arrhythmia
#9
Alexia Hennig, Marjorie Salel, Frederic Sacher, Claudia Camaioni, Soumaya Sridi, Arnaud Denis, Michel Montaudon, François Laurent, Pierre Jais, Hubert Cochet
Aims: Cardiac magnetic resonance (CMR) is recommended as a second-line method to diagnose ventricular arrhythmia (VA) substrate. We assessed the diagnostic yield of CMR including high-resolution late gadolinium-enhanced (LGE) imaging. Methods and results: Consecutive patients with sustained ventricular tachycardia (VT), non-sustained VT (NSVT), or ventricular fibrillation/aborted sudden death (VF/SCD) underwent a non-CMR diagnostic workup according to current guidelines, and CMR including LGE imaging with both a conventional breath-held and a free-breathing method enabling higher spatial resolution (HR-LGE)...
October 23, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29059484/imaging-characteristics-of-papillary-muscle-site-of-origin-of-ventricular-arrhythmias-in-patients-with-mitral-valve-prolapse
#10
Brian L Fulton, Jackson J Liang, Andres Enriquez, Fermin C Garcia, Gregory E Supple, Michael P Riley, Robert D Schaller, Sanjay Dixit, David J Callans, Francis E Marchlinski, Yuchi Han
BACKGROUND: Mitral valve prolapse has been associated with increased risk of ventricular arrhythmias. We aimed to examine whether certain cardiac imaging characteristics are associated with papillary muscle origin of ventricular arrhythmias in these patients. METHODS AND RESULTS: We screened electronic medical records of all patients documented to have mitral valve prolapse on either transthoracic echocardiogram (TTE) or cardiac magnetic resonance imaging (CMR) in our center, who also underwent an electrophysiologic study (EPS) between 2007 and 2016...
October 23, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/29051976/late-gadolinium-enhancement-on-cardiac-magnetic-resonance-imaging-is-associated-with-coronary-endothelial-dysfunction-in-patients-with-dilated-cardiomyopathy
#11
Mina Nakayama, Megumi Yamamuro, Seiji Takashio, Tomoaki Uemura, Naoki Nakayama, Kyoko Hirakawa, Seitaro Oda, Daisuke Utsunomiya, Koichi Kaikita, Seiji Hokimoto, Yasuyuki Yamashita, Yukiko Morita, Kazuo Kimura, Kouichi Tamura, Kenichi Tsujita
Myocardial fibrosis and coronary endothelial dysfunction are important determinants of outcome in patients with heart failure. However, the relationship of these factors in patients with dilated cardiomyopathy (DCM) is not fully understood. This study aimed to investigate the relationship between endothelium-dependent coronary vasomotor abnormality and late gadolinium enhancement (LGE) on cardiac magnetic resonance imaging (CMR) in patients with DCM. We examined 38 consecutive patients with DCM. All patients underwent CMR and the acetylcholine (ACh) provocation test using cardiac catheterization...
October 19, 2017: Heart and Vessels
https://www.readbyqxmd.com/read/29050981/evolutional-change-in-epicardial-fat-and-its-correlation-with-myocardial-diffuse-fibrosis-in-heart-failure-patients
#12
Cho-Kai Wu, Hao-Yuan Tsai, Mao-Yuan M Su, Yi-Fan Wu, Juey-Jen Hwang, Jiunn-Lee Lin, Lian-Yu Lin, Jien-Jiun Chen
OBJECTIVES: The aim of this study was to characterize the characteristics of epicardial fat (EAT) in different stage heart failure (HF) patients and its relationship between cardiac fibrosis. BACKGROUND: EAT is visceral adipose tissue that possesses inflammatory properties. Inflammation and obesity are associated with cardiac fibrosis, but the relationship between cardiac fibrosis and EAT is unknown. METHODS: EAT volume was measured using cardiac magnetic resonance imaging (CMR) in 180 subjects: 58 patients with systolic HF, 63 patients with HF and preserved ejection fraction, and 59 patients without HF...
September 4, 2017: Journal of Clinical Lipidology
https://www.readbyqxmd.com/read/29048460/cardiovascular-magnetic-resonance-imaging-in-patients-with-cardiac-implantable-electronic-devices-a-device-dependent-imaging-strategy-for-improved-image-quality
#13
Sebastian Hilbert, Cosima Jahnke, Susanne Loebe, Sabrina Oebel, Alexander Weber, Ricardo Spampinato, Sergio Richter, Michael Doering, Andreas Bollmann, Philipp Sommer, Gerhard Hindricks, Ingo Paetsch
Aims: To prospectively determine evaluability of routine cardiovascular magnetic resonance (CMR) diagnostic modules in a referral population of implanted rhythm device all-comers, and to establish a device-dependent CMR imaging strategy to achieve optimal image quality. Methods and results: One hundred and twenty-eight patients with cardiac implantable electronic devices [insertable cardiac monitoring system, n = 14; implantable loop-recorder, n = 21; pacemaker, n = 31; implantable cardioverter-defibrillator (ICD), n = 50; and cardiac resynchronization therapy defibrillator (CRT-D), n = 12] underwent clinically indicated CMR at 1...
October 18, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/29036973/-predictive-value-of-cardiac-magnetic-resonance-derived-parameters-on-the-improvement-of-left-ventricular-function-in-patients-with-acute-viral-myocarditis
#14
H C Ouyang, F C Ouyang, L L Mai, Y Y Chen, Y Z Hu, H X Chen, W S Li
Objective: To evaluate the predictive value of cardiac magnetic resonance (CMR)-derived parameters on the improvement of left ventricular function in patients with acute viral myocarditis. Methods: Forty patients, who referred for acute viral myocarditis in our hospital from September 2011 to September 2015, were prospectively enrolled in this study.All patients were examined by CMR during hospitalization for acute viral myocarditis (baseline) and after 12 months.The CMR sequences include: two dimension steady state free precession, 2D SSFP; triple inversion recovery, triple IR; early gadolinium enhancement; phase sensitive inversion recovery turbo field echo, PSIR TFE...
September 24, 2017: Zhonghua Xin Xue Guan Bing za Zhi
https://www.readbyqxmd.com/read/29027095/multimodality-imaging-of-pericardial-diseases
#15
REVIEW
Mouaz H Al-Mallah, Fatimah Almasoudi, Mohamed Ebid, Amjad M Ahmed, Abdelrahman Jamiel
Pericardial diseases have changed their epidemiology in the past few years. With the aging population and decreasing incidence of communicable diseases, the causes of pericardial diseases have significantly changed from infectious and malignant to postradiation and cardiac surgery causes. Despite that, pericardial diseases remain difficult to diagnose. The accurate and timely diagnosis of these diseases is essential to avoid the late sequela of pericardial constriction and pericardial cirrhosis. Echocardiography remains the first test of choice for the assessment of patients with suspected pericardial diseases...
October 12, 2017: Current Treatment Options in Cardiovascular Medicine
https://www.readbyqxmd.com/read/29025553/prognostic-value-of-cardiac-magnetic-resonance-tissue-characterization-in-risk%C3%A2-stratifying-patients-with-suspected%C3%A2-myocarditis
#16
Christoph Gräni, Christian Eichhorn, Loïc Bière, Venkatesh L Murthy, Vikram Agarwal, Kyoichi Kaneko, Sarah Cuddy, Ayaz Aghayev, Michael Steigner, Ron Blankstein, Michael Jerosch-Herold, Raymond Y Kwong
BACKGROUND: Diagnosing myocarditis is challenged by nonspecific clinical signs and symptoms and low accuracy of endomyocardial biopsy. Cardiac magnetic resonance imaging (CMR) provides both cardiac anatomy and tissue characterization in this setting, but the prognostic value of this method as a primary assessment tool in patients with suspected myocarditis remains limited. OBJECTIVES: This study sought to determine cardiac event-free survival of a consecutive cohort with suspected myocarditis with regard to CMR findings...
October 17, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/29021848/scar-characteristics-derived-from-two-and-three-dimensional-reconstructions-of-cardiac-contrast-enhanced-magnetic-resonance-images-relationship-to-ventricular-tachycardia-inducibility-and-ablation-success
#17
Kazumasa Sonoda, Yasuo Okumura, Ichiro Watanabe, Koichi Nagashima, Hiroaki Mano, Rikitake Kogawa, Naoko Yamaguchi, Keiko Takahashi, Kazuki Iso, Kimie Ohkubo, Toshiko Nakai, Satoshi Kunimoto, Atsushi Hirayama
BACKGROUND: The relationship between cardiac contrast-enhanced magnetic resonance imaging (CE-MRI)-derived scar characteristics and substrate for ventricular tachycardia (VT) in patients with structural heart disease (SHD) has not been fully investigated. METHODS: This study included 51 patients (mean age, 63.3±15.1 years) who underwent CE-MRI with SHD and VT induction testing before ablation. Late gadolinium-enhanced (LGE) regions on MRI slices were quantified by thresholding techniques...
October 2017: Journal of Arrhythmia
https://www.readbyqxmd.com/read/29017930/cardiac-magnetic-resonance-imaging-using-wideband-sequences-in-patients-with-nonconditional-cardiac-implanted-electronic-devices
#18
Duc H Do, Vaughn Eyvazian, Aileen J Bayoneta, Peng Hu, J Paul Finn, Jason S Bradfield, Kalyanam Shivkumar, Noel G Boyle
BACKGROUND: Magnetic resonance imaging (MRI) has been performed safely in patients without MRI-conditional cardiac implantable electronic devices (CIEDs), but experience specifically with cardiac magnetic resonance imaging (CMR) is limited in this patient population. OBJECTIVE: Evaluate the safety of CMR in non-MRI-conditional CIEDs and the interpretability of images using wideband sequences. METHODS: We performed 114 consecutive CMR studies in 111 patients (mean age 59 ± 14 years, with 12 pacemakers, 73 implantable cardioverter defibrillators, 29 biventricular defibrillators) using a wideband pulse sequence for late gadolinium enhancement (LGE) imaging...
October 7, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/28984614/progression-of-duchenne-cardiomyopathy-presenting-with-chest-pain-and-troponin-elevation
#19
Kan N Hor, Pace Johnston, Kathi Kinnett, May Ling Mah, Corey Stiver, Larry Markham, Linda Cripe
BACKGROUND: Improved neuromuscular and respiratory therapies have altered the natural history of Duchenne muscular dystrophy (DMD) such that the most common cause of mortality is progressive cardiomyopathy. Despite imaging evidence of progressive cardiomyopathy, troponin I (cTn) is not significantly elevated in asymptomatic DMD patients. RESULTS: We describe eight boys with DMD evaluated for acute chest pain (ACP) and found to have acute cTn elevation with depressed left ventricular ejection fraction (LVEF)...
October 5, 2017: Journal of Neuromuscular Diseases
https://www.readbyqxmd.com/read/28950314/prognostic-impact-of-unrecognized-myocardial-scar-in-the-non-culprit-territories-by-cardiac-magnetic-resonance-imaging-in-patients-with-acute-myocardial-infarction
#20
Taku Omori, Tairo Kurita, Kaoru Dohi, Akihiro Takasaki, Tomoyuki Nakata, Shiro Nakamori, Naoki Fujimoto, Kakuya Kitagawa, Kozo Hoshino, Takashi Tanigawa, Hajime Sakuma, Masaaki Ito
Aims: Unrecognized myocardial scar by late gadolinium enhancement (LGE) magnetic resonance imaging (MRI) is strongly associated with cardiac event in patients with stable coronary artery disease. The purpose of this study was to evaluate the prognostic impact of unrecognized non-infarct-related LGE (non-IR-LGE) in patients with acute myocardial infarction (AMI). Methods and results: We studied 269 patients with a first clinical episode of AMI underwent cardiac MRI within 6 weeks after onset (209 men; age, 66 ± 12 years)...
July 27, 2017: European Heart Journal Cardiovascular Imaging
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