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https://www.readbyqxmd.com/read/28099705/prevalence-of-induced-abortions-and-contraceptive-use-among-married-women-in-an-urban-slum-of-delhi-india
#1
Meenakshi Bhilwar, Panna Lal, Nandini Sharma, Preena Bhalla, Ashok Kumar
OBJECTIVE: To document abortion practices and contraceptive use among women of reproductive age in an urban slum of Delhi. METHODS: Data were collected as part of a cross-sectional study conducted in an urban resettlement colony in the North East District of Delhi between November 2010 and December 2011. Systematic random sampling was used to enroll 200 married women aged 15-49 years from each of the four blocks of the colony. Participants were interviewed and data were entered into a pretested semi-structured questionnaire...
January 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/28094895/a-simple-2d-composite-image-analysis-technique-for-the-crystal-growth-study-of-l-ascorbic-acid
#2
Krishan Kumar, Virender Kumar, Jatin Lal, Harmeet Kaur, Jasbir Singh
This work was destined for 2D crystal growth studies of l-ascorbic acid using the composite image analysis technique. Growth experiments on the l-ascorbic acid crystals were carried out by standard (optical) microscopy, laser diffraction analysis, and composite image analysis. For image analysis, the growth of l-ascorbic acid crystals was captured as digital 2D RGB images, which were then processed to composite images. After processing, the crystal boundaries emerged as white lines against the black (cancelled) background...
January 17, 2017: Microscopy Research and Technique
https://www.readbyqxmd.com/read/28088941/fracture-union-in-percutaneous-kirschner-wire-fixation-in-paediatric-tibial-shaft-fractures
#3
Ramji Lal Sahu, Rajni Ranjan
PURPOSE: To evaluate the efficacy of intramedullary Kirschner wires for the treatment of unstable tibial shaft fractures in children. METHODS: This prospective study was conducted at the Department of Orthopaedic Surgery in Maharishi Markandeshwar Medical College from June 2005 to June 2010. Sixty-six children having closed fracture of the tibial shaft with a mean age of 7.7 years (range, 2-14 years) were recruited from emergency and outpatient department. They were treated with percutaneous intramedullary Kirschner wires...
December 1, 2016: Chinese Journal of Traumatology, Zhonghua Chuang Shang za Zhi
https://www.readbyqxmd.com/read/28087977/fibroblast-growth-factor-23-fgf23-in-untreated-nephrotic-syndrome
#4
Ashok Kumar Yadav, Raja Ramachandran, Abhinav Aggarwal, Vinod Kumar, Krishan Lal Gupta, Vivekanand Jha
AIM: Despite its importance in bone and cardiovascular disease in subjects with kidney disease, there is no data on fibroblast growth factor 23 (FGF23) perturbations in nephrotic syndrome. We evaluated FGF23 and markers of mineral bone metabolism in subjects with untreated NS. METHODS: In this cross-sectional study, we measured circulating levels of FGF23, 25-hydroxy vitamin D [25(OH)D], 1,25 di-hydroxy vitamin D [1,25(OH)2 D], serum albumin, serum calcium, phosphorus, creatinine and intact parathyroid hormone (iPTH) in 101 patients with adults onset NS and 40 healthy controls...
January 14, 2017: Nephrology
https://www.readbyqxmd.com/read/28078732/a-fleshy-growth-below-the-nail-plate-in-an-elderly-man
#5
Neetu Bhari, Vinod K Sharma, B Lal Jangid, Sudheer Arava, Anurag Srivastava
No abstract text is available yet for this article.
January 11, 2017: International Journal of Dermatology
https://www.readbyqxmd.com/read/28076357/soil-leaf-and-root-ecological-stoichiometry-of-caragana-korshinskii-on-the-loess-plateau-of-china-in-relation-to-plantation-age
#6
Quanchao Zeng, Rattan Lal, Yanan Chen, Shaoshan An
Caragana korshinskii, a leguminous shrub, a common specie, is widely planted to prevent soil erosion on the Loess Plateau. The objective of this study was to determine how the plantation ages affected soil, leaf and root nutrients and ecological stoichiometry. The chronosequence ages of C. korshinskii plantations selected for this study were 10, 20 and 30 years. Soil organic carbon (SOC) and soil total nitrogen (STN) of C. korshinskii plantations significantly increased with increase in the chronosequence age...
2017: PloS One
https://www.readbyqxmd.com/read/28075376/the-new-high-resolution-crystal-structure-of-ns2b-ns3-protease-of-zika-virus
#7
Syed Lal Badshah, Abdul Naeem, Yahia Mabkhot
Zika virus (ZIKV) is the cause of a significant viral disease affecting humans, which has spread throughout many South American countries and has also become a threat to Southeastern Asia. This commentary discusses the article "Crystal structure of unlinked NS2B-NS3 protease from Zika virus" published recently in the journal Science by Zhang et al. of Nanyang Technological University, Singapore. They resolved a 1.58 Å resolution structure of the NS2B-NS3 protease of ZIKV and demonstrated how peptide and non-peptide inhibitors interact with this structure, along with the different conformational states that were observed...
January 10, 2017: Viruses
https://www.readbyqxmd.com/read/28074809/holt-oram-syndrome-anesthetic-challenges-and-safe-outcome
#8
Meenal Rana, Sohan Lal Solanki, Vandana Agarwal, Jigeeshu V Divatia
Holt-Oram syndrome (HOS) is an autosomal dominant disease with skeletal and cardiac manifestations. We here are presenting a 31-year-old man and a diagnosed case of HOS, with an ulceroproliferative lesion on lateral border of the tongue, was posted for wide excision of lesion with primary closure and left side radical neck dissection.
January 2017: Annals of Cardiac Anaesthesia
https://www.readbyqxmd.com/read/28074664/recent-advances-in-molecular-biomarkers-for-diabetes-mellitus-a-systematic-review
#9
Ty Lees, Najah Nassif, Ann Simpson, Fatima Shad-Kaneez, Rose Martiniello-Wilks, Yiguang Lin, Allan Jones, Xianqin Qu, Sara Lal
CONTEXT: Diabetes is a growing global metabolic epidemic. Current research is focusing on exploring how the biological processes and clinical outcomes of diabetes are related and developing novel biomarkers to measure these relationships, as this can subsequently improve diagnostic, therapeutic and management capacity. OBJECTIVE: To identify the most recent advances in molecular biomarkers of diabetes and directions that warrant further research. METHODS: Using a systematic search strategy, the MEDLINE, CINAHL and OVID MEDLINE databases were canvassed for articles that investigated molecular biomarkers for diabetes...
January 11, 2017: Biomarkers: Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals
https://www.readbyqxmd.com/read/28073363/swept-away-ocean-currents-and-seascape-features-influence-genetic-structure-across-the-18-000-km-indo-pacific-distribution-of-a-marine-invertebrate-the-black-lip-pearl-oyster-pinctada-margaritifera
#10
Monal M Lal, Paul C Southgate, Dean R Jerry, Cyprien Bosserelle, Kyall R Zenger
BACKGROUND: Genetic structure in many widely-distributed broadcast spawning marine invertebrates remains poorly understood, posing substantial challenges for their fishery management, conservation and aquaculture. Under the Core-Periphery Hypothesis (CPH), genetic diversity is expected to be highest at the centre of a species' distribution, progressively decreasing with increased differentiation towards outer range limits, as populations become increasingly isolated, fragmented and locally adapted...
January 10, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28069069/arresting-kinase-suppressor-of-ras-in-an-inactive-state
#11
EDITORIAL
Syed Lal Badshah, Yahia Mabkhot
Ras protein signaling pathways are important in controlling the plight of different types of cancer. Here we discussed the paper entitled "Small molecule stabilization of the KSR inactive state antagonizes oncogenic Ras signalling" published in Nature journal on inactivating the kinase suppressor of Ras (KSR) protein using a small molecule as an inhibitor by Dhawan et al. A biphenyl ether analogue of a quinazoline binds in one of the binding pockets of KSR and results in stabilization of its inactive state...
January 9, 2017: Chinese Journal of Cancer
https://www.readbyqxmd.com/read/28068212/immunogenicity-and-safety-of-an-adjuvanted-herpes-zoster-subunit-candidate-vaccine-in-adults-%C3%A2-50%C3%A2-years-of-age-with-a-prior-history-of-herpes-zoster-a-phase-iii-non-randomized-open-label-clinical-trial
#12
Olivier Godeaux, Martina Kovac, Daniel Shu, Katrijn Grupping, Laura Campora, Martine Douha, Thomas C Heineman, Himal Lal
This phase III, non-randomized, open-label, multi-center study (NCT01827839) evaluated the immunogenicity and safety of an adjuvanted recombinant subunit herpes zoster (HZ) vaccine (HZ/su) in adults aged ≥50 years with prior physician-documented history of HZ. Participants (stratified by age: 50-59, 60-69 and ≥70 years) received 2 doses of HZ/su 2 months apart and were followed-up for another 12 months. Anti-glycoprotein E (gE) antibodies were measured by enzyme-linked immunosorbent assay before vaccination and 1 month after the second dose (Month 3)...
January 9, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/28056073/statistical-approaches-for-gene-selection-hub-gene-identification-and-module-interaction-in-gene-co-expression-network-analysis-an-application-to-aluminum-stress-in-soybean-glycine-max-l
#13
Samarendra Das, Prabina Kumar Meher, Anil Rai, Lal Mohan Bhar, Baidya Nath Mandal
Selection of informative genes is an important problem in gene expression studies. The small sample size and the large number of genes in gene expression data make the selection process complex. Further, the selected informative genes may act as a vital input for gene co-expression network analysis. Moreover, the identification of hub genes and module interactions in gene co-expression networks is yet to be fully explored. This paper presents a statistically sound gene selection technique based on support vector machine algorithm for selecting informative genes from high dimensional gene expression data...
2017: PloS One
https://www.readbyqxmd.com/read/28052576/pre-operative-oral-nutritional-supplementation-with-dietary-advice-versus-dietary-advice-alone-in-weight-losing-patients-with-colorectal-cancer-single-blind-randomized-controlled-trial
#14
Sorrel T Burden, Debra J Gibson, Simon Lal, James Hill, Mark Pilling, Mattias Soop, Aswatha Ramesh, Chris Todd
BACKGROUND: Pre-operative weight loss has been consistently associated with increased post-operative morbidity. The study aims to determine if pre-operative oral nutritional supplements (ONSs) with dietary advice reduce post-operative complications. METHODS: Single-blinded randomized controlled trial. People with colorectal cancer scheduled for surgery with pre-operative weight loss >1 kg/3-6 months were randomized by using stratified blocks (1:1 ratio) in six hospitals (1 November 2013-28 February 2015)...
January 3, 2017: Journal of Cachexia, Sarcopenia and Muscle
https://www.readbyqxmd.com/read/28042687/unsupervised-network-mapping-of-commercially-available-immunoassay-yields-three-distinct-chronic-rhinosinusitis-endotypes
#15
Rohit Divekar, Matthew Rank, Diane Squillace, Hirohito Kita, Devyani Lal
BACKGROUND: Endotyping chronic rhinosinusitis (CRS) through simplified cytokine assays may help direct individualized therapy such as corticosteroids, antibiotics, or biologics. We performed an unsupervised network analysis to endotype CRS and control subjects using a commercially available cytokine-chemokine immunoassay. METHODS: A 41-plex cytokine-chemokine array along with major basic protein (MBP) assay was performed on sinonasal surgical tissue of 32 adults...
January 2, 2017: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/28041793/motile-cilia-mediated-flow-improves-sensitivity-and-temporal-resolution-of-olfactory-computations
#16
Ingrid Reiten, Fazil Emre Uslu, Stephanie Fore, Robbrecht Pelgrims, Christa Ringers, Carmen Diaz Verdugo, Maximillian Hoffman, Pradeep Lal, Koichi Kawakami, Kerem Pekkan, Emre Yaksi, Nathalie Jurisch-Yaksi
Motile cilia are actively beating hair-like structures that cover the surface of multiple epithelia. The flow that ciliary beating generates is utilized for diverse functions and depends on the spatial location and biophysical properties of cilia. Here we show that the motile cilia in the nose of aquatic vertebrates are spatially organized and stably beat with an asymmetric pattern, resulting in a robust and stereotypical flow around the nose. Our results demonstrate that these flow fields attract odors to the nose pit and facilitate detection of odors by the olfactory system in stagnant environments...
December 21, 2016: Current Biology: CB
https://www.readbyqxmd.com/read/28039281/association-of-rate-dependent-conduction-block-between-eccentric-coronary-sinus-to-left-atrial-connections-with-inducible-atrial-fibrillation-and-flutter
#17
Dong Huang, Joseph E Marine, Jing-Bo Li, Tarek Zghaib, Esra Gucuk Ipek, Sunil Sinha, David D Spragg, Hiroshi Ashikaga, Ronald D Berger, Hugh Calkins, Saman Nazarian
BACKGROUND: We sought to describe the prevalence and variability of coronary sinus (CS) and left atrial (LA) myocardium connections, their susceptibility to rate-dependent conduction block, and association with atrial fibrillation (AF) and flutter induction. METHODS AND RESULTS: The study cohort included 30 consecutive AF patients (age 63.3±10.5 years, 63% male). Multipolar catheters were positioned in the CS, high right atrium (HRA), and LA parallel to and near the CS...
January 2017: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/28028331/correlation-between-cytological-and-histological-grading-of-breast-cancer-and-its-role-in-prognosis
#18
Shweta Pal, Mohan Lal Gupta
CONTEXT: Assigning grade to breast cancer on FNAC provides prognostic information and guides optimal therapy. AIMS: The present study was undertaken to grade breast carcinoma on cytology by Robinson's grading system and correlate it with Elstons modified Bloom Richardson histological grading system. SETTINGS AND DESIGN: It is a prospective study done on fifty cases of breast cancer reported on cytology. MATERIALS AND METHODS: Fifty patients who underwent FNAC and mastectomy for breast carcinoma were cytologically and histologically graded...
October 2016: Journal of Cytology
https://www.readbyqxmd.com/read/28027797/corrigendum-to-espen-guidelines-on-chronic-intestinal-failure-in-adults-clin-nutr-35-2-2016-247-307
#19
Loris Pironi, Jann Arends, Federico Bozzetti, Cristina Cuerda, Lyn Gillanders, Palle Bekker Jeppesen, Francisca Joly, Darlene Kelly, Simon Lal, Michael Staun, Kinga Szczepanek, André Van Gossum, Geert Wanten, Stéphane Michel Schneider
No abstract text is available yet for this article.
December 23, 2016: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28018613/synthesis-and-characterization-of-azo-guanidine-based-alcoholic-media-naked-eye-dna-sensor
#20
Ataf Ali Altaf, Uzma Hashmat, Muhammad Yousaf, Bhajan Lal, Shafiq Ullah, Alvin A Holder, Amin Badshah
DNA sensing always has an open meadow of curiosity for biotechnologists and other researchers. Recently, in this field, we have introduced an emerging class of molecules containing azo and guanidine functionalities. In this study, we have synthesized three new compounds (UA1, UA6 and UA7) for potential application in DNA sensing in alcoholic medium. The synthesized materials were characterized by elemental analysis, FTIR, UV-visible, (1)H NMR and (13)C NMR spectroscopies. Their DNA sensing potential were investigated by UV-visible spectroscopy...
November 2016: Royal Society Open Science
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