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https://www.readbyqxmd.com/read/28812058/environmental-pollutants-and-neurodevelopment-review-of-benefits-from-closure-of-a-coal-burning-power-plant-in-tongliang-china
#1
Vrinda Kalia, Frederica Perera, Deliang Tang
Background. Understanding preventable causes of neurodevelopmental disorders is a public health priority. Polycyclic aromatic hydrocarbons (PAH) from combustion of fossil fuel, lead, and mercury are among known neurodevelopmental toxicants. Method. For the first time, we comprehensively review the findings from a study by the Columbia Center for Children's Environmental Health and Chinese partners that followed 2 groups of mother-child pairs, one from 2002 and another from 2005, in Tongliang County, China. Pregnant mothers in the 2 cohorts experienced different exposure to PAH because a local coal-burning power plant was shut down in 2004...
2017: Global Pediatric Health
https://www.readbyqxmd.com/read/28807206/graft-loss-review-of-a-single-burn-center-s-experience-and-proposal-of-a-graft-loss-grading-scale
#2
Lauren B Nosanov, Melissa M McLawhorn, Lamisa Hassan, Taryn E Travis, Shawn Tejiram, Laura S Johnson, Lauren T Moffatt, Jeffrey W Shupp
BACKGROUND: There exists neither a consensus definition of burn "graft loss" nor a scale with which to grade severity. We introduced an institutional scale in 2014 for quality improvement. MATERIALS AND METHODS: We reviewed all burned patients with graft loss on departmental Morbidity and Mortality reports between July 2014 and July 2016. Graft loss grades were assigned during the course of clinical care per institutional scale. Chronic nonhealing wounds and nonburn wounds were excluded...
August 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28803724/implementation-and-outcomes-of-an-evidence-based-precepting-program-for-burn-nurses
#3
Johnnie R Robbins, Krystal K Valdez-Delgado, Nicole W Caldwell, Linda H Yoder, Elizabeth J Hayes, Michaèl G Barba, Hope L Greeley, Colleen Mitchell, Elizabeth A Mann-Salinas
INTRODUCTION: There is significant nationwide interest in transitioning new and new-to-specialty nurses into practice, especially in burn care. Lack of a structured transition program in our Burn Center was recognized as a contributing factor for nursing dissatisfaction and increased turnover compared to other hospital units. Employee evaluations exposed a need for more didactic instruction, hands-on learning, and preceptor support. The goal of this project was to implement an evidence-based transition to practice program specific to the burn specialty...
August 10, 2017: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/28803363/evaluation-of-nonablative-fractional-laser-treatment-in-scar-reduction
#4
Hilal Gokalp
Fractional lasers have been used for the improvement of scar tissue in the recent years but there has not been extensive research on their impact. The purpose of this study was to evaluate the efficacy of nonablative fractional laser (NAFL) on acne, burn, and surgery/traumatic scar. The scars were also categorized as atrophic, hypertrophic, and keloid, and treatment efficacy was investigated accordingly. This is a retrospective, single-center study. Scar tissues were treated using a nonablative fractional 1550-nm Erbium glass laser in high-energy parameters at 4-week interval for 4-8 sessions...
August 12, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28801338/rituximab-as-treatment-for-anti-musk-myasthenia-gravis-multicenter-blinded-prospective-review
#5
Michael K Hehir, Lisa D Hobson-Webb, Michael Benatar, Carolina Barnett, Nicholas J Silvestri, James F Howard, Diantha Howard, Amy Visser, Brian A Crum, Richard Nowak, Rachel Beekman, Aditya Kumar, Katherine Ruzhansky, I-Hweii Amy Chen, Michael T Pulley, Shannon M LaBoy, Melissa A Fellman, Shane M Greene, Mamatha Pasnoor, Ted M Burns
OBJECTIVE: To evaluate the efficacy of rituximab in treatment of anti-muscle-specific kinase (MuSK) myasthenia gravis (MG). METHODS: This was a multicenter, blinded, prospective review, comparing anti-MuSK-positive patients with MG treated with rituximab to those not treated with rituximab. The primary clinical endpoint was the Myasthenia Gravis Status and Treatment Intensity (MGSTI), a novel outcome that combines the Myasthenia Gravis Foundation of America (MGFA) postintervention status (PIS) and the number and dosages of other immunosuppressant therapies used...
August 11, 2017: Neurology
https://www.readbyqxmd.com/read/28797868/neuropathic-pain-and-nerve-growth-factor-in-chemotherapy-induced-peripheral-neuropathy-prospective-clinical-pathological-study
#6
R Velasco, X Navarro, M Gil-Gil, M Herrando-Grabulosa, A Calls, J Bruna
CONTEXT: Neuropathic pain can be present in patients developing chemotherapy-induced peripheral neuropathy (CIPN). Nerve growth factor (NGF) is trophic to small sensory fibers and regulates nociception. OBJECTIVES: We investigated the changes in serum NGF and intraepidermal nerve fiber density (IENFD) in skin biopsies of cancer patients receiving neurotoxic chemotherapy in a single-center prospective observational study. METHODS: Patients were evaluated before and after chemotherapy administration...
August 7, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/28797577/comparison-of-two-dimensional-methods-versus-three-dimensional-scanning-systems-in-the-assessment-of-total-body-surface-area-estimation-in-burn-patients
#7
Helene Retrouvey, Justin Chan, Shahriar Shahrokhi
BACKGROUND: Accurate measurement of percent total body surface area (%TBSA) burn is crucial in the management of burn patients for calculating the estimated fluid resuscitation, determining the need to transfer to a specialized burn unit and probability of mortality. %TBSA can be estimated using many methods, all of which are relatively inaccurate. Three-dimensional (3D) systems have been developed to improve %TBSA calculation and consequently optimize clinical decision-making. The objective of this study was to compare the accuracy of percent total burn surface area calculation by conventional methods against novel 3D methods...
August 7, 2017: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/28797571/epidemiology-of-burn-patients-presenting-to-a-tertiary-hospital-emergency-department-in-lebanon
#8
Abou Dagher Gilbert, Eva Rajha, Christopher El Khuri, Ralph Bou Chebl, Aurelie Mailhac, Maha Makki, Mazen El Sayed
BACKGROUND: The epidemiology of burns is well described in the United States, Europe and Asia. However, few studies address this topic in the Levant region. This study aims to describe characteristics of burn victims treated at the emergency department of a tertiary care center in Beirut, Lebanon and to report on factors that affect ED disposition. METHODS: A retrospective cohort study was conducted in the ED of a tertiary care hospital, in Beirut, Lebanon, between 2009 and 2013...
August 7, 2017: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/28795063/determinants-of-mortality-and-the-lethal-area-50-index-la50-in-burn-patients-admitted-to-a-large-burn-center-a-single-center-experience
#9
Shahab Shahabi Shahmiri, Mohsen Kolahdouzan, Ara Omrani, Mehdi Khazaei, Hamid Salehi, Abbas Motavalian, Rastin Mohammadi Mofrad, Mohammad Taghi Rezaei, Helia Hemasian
OBJECTIVES: To investigate the determinants of mortality and the lethal area 50 (LA50) in large series of Iranian burn patients admitted to a single burn center. METHODS: This cross-sectional study was conducted in Shahid Motahari burn center of Tehran, Iran during a 1-year period from 2011 to 2012. We included all the burn patients who were admitted to our center during the study period. Those with incomplete medical records and those referred to other centers were excluded from the study...
July 2017: Bulletin of Emergency and Trauma
https://www.readbyqxmd.com/read/28795062/comparison-of-the-results-of-early-excision-and-grafting-between-children-and-adults-a-prospective-comparative-study
#10
Mehdi Ayaz, Abdolkhalegh Keshavarzi, Hamid Bahadoran, Peyman Arasteh, Sam Moslemi
OBJECTIVES: To compare the outcomes of early excision and grafting between pediatric and adult patients with deep burns of less than 40% total body surface area burns (TBSA). METHODS: This is a prospective comparative study. Overall, 106 patients admitted to Ghotbodin Burn Center in Shiraz, Iran from September 2012 to September 2013, were included in the study. All patients had less than 40% TBSA burn and had excision and grafting under 14 days from their injury...
July 2017: Bulletin of Emergency and Trauma
https://www.readbyqxmd.com/read/28789802/fatalities-from-a-greek-burn-unit-a-clinicopathological-correlation-of-129-cases
#11
Myron Tsagkarakis, Georgia-Alexandra Spyropoulou, Leonidas Pavlidis, Othon Kritikos, Nikolaos Karakoukis, Evgenia Kyriopoulos, Dimosthenis Tsoutsos
INTRODUCTION: This is a retrospective study of the hospital data and autopsy reports of burn patients who died in the Burn Unit of the Department of Plastic and Reconstructive Surgery, Microsurgery and Burn Center of "G. Gennimatas" Hospital of Athens, Greece during the period 1999-2005. MATERIALS AND METHODS: The records of the burn victims deceased during the period 1999-2005 were reviewed and the cause of injury, percentage of body surface area (BSA) burned, age, gender, and co-morbidities were documented...
August 5, 2017: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/28783329/the-propensity-of-uranium-peroxide-systems-to-preserve-nanosized-assemblies
#12
Mateusz Dembowski, Christopher A Colla, Ping Yu, Jie Qiu, Jennifer E S Szymanowski, William H Casey, Peter C Burns
Understanding the stability fields and decomposition products of various metal- and actinide-oxide nanoclusters is essential for their development into useful materials for industrial processes. Herein, we explore the spontaneous transformation of the sulfate-centered, phosphate functionalized uranyl peroxide nanocluster {U20P6} to {U24} under aqueous ambient conditions using time-resolved small-angle X-ray scattering, Raman, and (31)P NMR spectroscopy. We show that the unusual μ-η(1):η(2) bridging mode of peroxide between uranyl ions observed in {U20P6} may lead to its rapid breakdown in solution as evidenced by liberation of phosphate groups that were originally present as an integral part of its cage structure...
August 7, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28781135/five-year-epidemiology-of-liquefied-petroleum-gas-related-burns
#13
Ronghua Jin, Pan Wu, Jon Kee Ho, Xingang Wang, Chunmao Han
BACKGROUND: The incidence of liquefied petroleum gas (LPG)-related burns has increased over recent years, and it has become a serious public health issue in developing countries such as India and Turkey. This paper aims to investigate the epidemiological characteristics of LPG-related burns to provide assistance and suggestions for planning prevention strategies. METHODS: A 5-year retrospective study was conducted in patients with LPG-related burns admitted to the Department of Burns & Wound Care Center, Second Affiliated Hospital of Zhejiang University, College of Medicine, between 1st January 2011 and 31st December 2015...
August 3, 2017: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/28776776/ten-treatment-without-immunosuppressive-therapy-in-a-burn-centre-a-series-of-10-cases
#14
P Gacto, J J Pereyra, J Carbajal, T Gomez-Cía, J Conejo-Mir
Toxic epidermal necrolysis (TEN) is a serious and infrequent skin disease, usually secondary to drugs. Since the disease includes severe exfoliative disease it has been treated in Burn Centers due to large skin losses. The mechanism leading to the development of lesions is not fully known; the main role is attributed to dysfunction of T lymphocytes (1). The mortality, ranging from 10% to 70% (2), predominantly results from severe complications of multiple organ failure and infections affecting extensive areas of inflamed skin...
August 4, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28769977/predisposing-factors-of-ischemic-colitis-data-from-14-years-of-experience-in-a-single-center
#15
Hyun Il Seo, Kyoo-Ho Choi, Koon Hee Han, Sang Jin Lee, Jong Kyu Park, Young Don Kim, Gab Jin Cheon
BACKGROUND AND AIMS: While several case reports on ischemic colitis (IC) suggest the presence of predisposing causative factors, a few studies have investigated the predisposing factors in IC. This study aimed to identify the characteristics of patients with IC, particularly focusing on the predisposing factors. METHODS: We conducted a single-center, retrospective analysis of 159 patients with IC. Clinical characteristics, laboratory data, endoscopic findings, and medical records were reviewed...
2017: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/28768847/cross-sectional-analysis-of-a-large-cohort-with-x-linked-charcot-marie-tooth-disease-cmtx1
#16
Francis B Panosyan, Matilde Laura, Alexander M Rossor, Chiara Pisciotta, Giuseppe Piscosquito, Joshua Burns, Jun Li, Sabrina W Yum, Richard A Lewis, John Day, Rita Horvath, David N Herrmann, Michael E Shy, Davide Pareyson, Mary M Reilly, Steven S Scherer
OBJECTIVE: To extend the phenotypic description of Charcot-Marie-Tooth disease (CMTX1) and to draw new genotype-phenotype relationships. METHODS: Mutations in GJB1 cause the main X-linked form of CMTX (CMTX1). We report cross-sectional data from 160 patients (from 120 different families, with 89 different mutations) seen at the Inherited Neuropathies Consortium centers. RESULTS: We evaluated 87 males who had a mean age of 41 years (range 10-78 years) and 73 females who had a mean age of 46 years (range 15-84 years)...
August 2, 2017: Neurology
https://www.readbyqxmd.com/read/28761956/should-this-patient-receive-an-antidepressant-grand-rounds-discussion-from-beth-israel-deaconess-medical-center
#17
Risa B Burns, Gerald W Smetana, Roscoe Brady
Depression is a major public health problem and a common cause of disability. To help physicians choose among available treatment options, the American College of Physicians recently issued a guideline titled "Nonpharmacologic Versus Pharmacologic Treatment of Adult Patients with Major Depressive Disorder." The evidence review done for the guideline found no statistically significant difference in the efficacy of second-generation antidepressants (SGAs) versus most other treatments for this disorder. However, rates of adverse events and discontinuation were generally higher in patients treated with SGAs...
August 1, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/28757086/multidrug-resistant-acinetobacter-risk-factors-and-outcomes-in-veterans-with-spinal-cord-injuries-and-disorders
#18
Swetha Ramanathan, Katie J Suda, Margaret A Fitzpatrick, Linda Poggensee, Sherri L LaVela, Stephen P Burns, Charlesnika T Evans
BACKGROUND: Multidrug-resistant (MDR) Acinetobacter is a growing concern and has been identified as a serious threat by the Centers for Disease Control and Prevention. However, there is little information on MDR Acinetobacter in individuals with spinal cord injuries and disorders (SCI/Ds). Therefore, the objective of this study was to identify risk factors for, and assess outcomes of, MDR Acinetobacter in veterans with SCI/Ds. METHODS: This was a retrospective cohort study from January 1, 2012-December 31, 2013, using national Veterans Affairs medical encounter and microbiology data...
July 27, 2017: American Journal of Infection Control
https://www.readbyqxmd.com/read/28754650/modeling-patient-treatment-with-medical-records-an-abstraction-hierarchy-to-understand-user-competencies-and-needs
#19
Justin D St-Maurice, Catherine M Burns
BACKGROUND: Health care is a complex sociotechnical system. Patient treatment is evolving and needs to incorporate the use of technology and new patient-centered treatment paradigms. Cognitive work analysis (CWA) is an effective framework for understanding complex systems, and work domain analysis (WDA) is useful for understanding complex ecologies. Although previous applications of CWA have described patient treatment, due to their scope of work patients were previously characterized as biomedical machines, rather than patient actors involved in their own care...
July 28, 2017: JMIR Human Factors
https://www.readbyqxmd.com/read/28753002/efficient-formation-of-light-absorbing-polymeric-nanoparticles-from-the-reaction-of-soluble-fe-iii-with-c4-and-c6-dicarboxylic-acids
#20
Ashley Tran, Geoffrey Williams, Shagufta Younus, Nujhat Ali, Sandra Blair, Sergey A Nizkorodov, Hind A Al-Abadleh
The role of transition metals in the formation and aging of secondary organic aerosol (SOA) from aliphatic and aromatic precursors in heterogeneous/multiphase reactions is not well understood. The reactivity of soluble Fe(III) towards known benzene photooxidation products that include fumaric (trans-butenedioic) and muconic (trans, trans-2,4-hexadienedioic) acids was investigated. Efficient formation of brightly-colored nanoparticles was observed that are mostly rod- or irregularly-shaped depending on the structure of the organic precursor...
July 28, 2017: Environmental Science & Technology
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