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https://www.readbyqxmd.com/read/28326954/in-memoriam
#1
Gordan M Vujanic, Rita Alaggio
No abstract text is available yet for this article.
March 2017: Pediatric and Developmental Pathology
https://www.readbyqxmd.com/read/28325380/-aetiology-symptoms-and-complications-of-a-paediatric-stroke
#2
Frédérique Audic
In children, as in adults, a stroke corresponds to an acute neurological deficit, secondary to an injury to the cerebral parenchyma which may be of haemorrhagic or ischemic origin, or both. The term 'stroke' comprises a number of pathologies which are extremely heterogenous in terms of physiopathology, risk factors, clinical presentation, evolution and treatment.
March 2017: Soins. Pédiatrie, Puériculture
https://www.readbyqxmd.com/read/28302681/ultrasound-biomicroscopic-imaging-in-paediatric-ocular-toxocariasis
#3
Jinghua Liu, Songfeng Li, Guangda Deng, Wenli Yang, Wei Chen, Hai Lu
PURPOSE: To determine the potential and usefulness of ultrasound biomicroscopy (UBM) as a diagnostic procedure on a larger cohort of paediatric patients with ocular toxocariasis. METHODS: UBM was performed on 41 eyes of 41 patients with ocular toxocariasis in order to determine configuration of peripheral retina, pars plana and vitreous. Location and range of peripheral pathology using ophthalmoscopy with scleral indentation, UBM and intraoperative confirmation were recorded and compared...
March 16, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28299660/etv6-runx1-acute-lymphoblastic-leukaemia-in-identical-twins
#4
Anthony M Ford, Mel Greaves
Acute leukaemia is the major subtype of paediatric cancer with a cumulative risk of 1 in 2000 for children up to the age of 15 years. Childhood acute lymphoblastic leukaemia (ALL) is a biologically and clinically diverse disease with distinctive subtypes; multiple chromosomal translocations exist within the subtypes and each carries its own prognostic relevance. The most common chromosome translocation observed is the t(12;21) that results in an in-frame fusion between the first five exons of ETV6 (TEL) and almost the entire coding region of RUNX1 (AML1)...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28297089/cone-beam-computed-tomographic-imaging-in-orthodontics
#5
W C Scarfe, B Azevedo, S Toghyani, A G Farman
Over the last 15 years, cone beam computed tomographic (CBCT) imaging has emerged as an important supplemental radiographic technique for orthodontic diagnosis and treatment planning, especially in situations which require an understanding of the complex anatomic relationships and surrounding structures of the maxillofacial skeleton. CBCT imaging provides unique features and advantages to enhance orthodontic practice over conventional extraoral radiographic imaging. While it is the responsibility of each practitioner to make a decision, in tandem with the patient/family, consensus-derived, evidence-based clinical guidelines are available to assist the clinician in the decision-making process...
March 2017: Australian Dental Journal
https://www.readbyqxmd.com/read/28291024/pavlik-harness-treatment-for-pathological-developmental-dysplasia-of-the-hip-meeting-the-standard
#6
Qaisar Choudry, Robin W Paton
In the UK, the Pavlik harness is generally the accepted treatment technique for the treatment of neonatal and infant pathological developmental dysplasia of the hip. In 2013, the success rate of the Pavlik harness became an outcome measure from the British Society of Children's Orthopaedic Surgery for appraisal and revalidation with the GMC for paediatric orthopaedic surgery. The standard set requires an 80% success rate, with less than 20% requiring surgery. This study evaluated the outcomes of Pavlik harness treatment in neonates/infants with 'pathological hips' diagnosed by ultrasound imaging in a district general hospital setting...
March 13, 2017: Journal of Pediatric Orthopedics. Part B
https://www.readbyqxmd.com/read/28264584/clinicians-perspectives-of-therapeutic-alliance-in-face-to-face-and-telepractice-speech-language-pathology-sessions
#7
Anneka Freckmann, Monique Hines, Michelle Lincoln
PURPOSE: To investigate the face validity of a measure of therapeutic alliance for paediatric speech-language pathology and to determine whether a difference exists in therapeutic alliance reported by speech-language pathologists (SLPs) conducting face-to-face sessions, compared with telepractice SLPs or in their ratings of confidence with technology. METHOD: SLPs conducting telepractice (n = 14) or face-to-face therapy (n = 18) completed an online survey which included the Therapeutic Alliance Scales for Children - Revised (TASC-r) (Therapist Form) to rate clinicians' perceptions of rapport with up to three clients...
March 7, 2017: International Journal of Speech-language Pathology
https://www.readbyqxmd.com/read/28239996/re-presentations-and-recurrent-events-following-initial-management-of-the-acute-paediatric-scrotum-a-5-year-review
#8
Shareena Lala, Neil Price, Vipul Upadhyay
BACKGROUND: Previous reviews report relatively low rates of post-operative complications for acute scrotal exploration. The aim of this study was to evaluate the re-presentation to hospital in boys with previous acute scrotal pathology, reviewing contralateral symptoms, post-operative complications, testicular torsion following fixation and failure of conservative management of testicular appendage (TA) torsion. METHODS: All boys under 16 years presenting to our unit with an acute scrotum from January 2008 to December 2012 (5-year period) were identified...
February 27, 2017: ANZ Journal of Surgery
https://www.readbyqxmd.com/read/28236029/how-is-post-mortem-microbiology-appraised-by-pathologists-results-from-a-practice-survey-conducted-by-esgfor
#9
V Saegeman, M C Cohen, J Alberola, N Ziyade, C Farina, G Cornaglia, A Fernández-Rodríguez
Post-mortem microbiology (PMM) is an important tool in forensic pathology, assisting to determine the cause and manner of death. However, there is a lack of standardisation of PMM sampling. In order to get a better insight into the methods used, the available technical options and developmental needs, ESCMID Study Group for Forensic and Postmortem Microbiology (ESGFOR) members designed a survey aimed at pathologists regarding common practices of PMM in clinical and forensic autopsies. Multiple choice questions were developed based on Cumulative Techniques and Procedures in Clinical Microbiology (Cumitech)...
February 24, 2017: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/28218961/the-hemocue-wbc-diff-system-could-be-used-for-leucocyte-and-neutrophil-counts-but-not-for-full-differential-counts
#10
Malgorzata Karawajczyk, Saba Haile, Magnus Grabski, Anders Larsson
AIM: The aim of this study was to evaluate the HemoCue WBC DIFF system for point of care testing of fingerstick samples from paediatric patients. METHODS: We analysed 158 white blood cell counts on both the point of care HemoCue WBC DIFF instrument and the Cell Dyn Sapphire cell counter used by our central laboratory and compared the results. The measurements were performed using fingerstick samples drawn by nurses working in paediatric emergency and paediatric oncology units...
February 20, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28197949/the-impact-of-next-generation-sequencing-on-the-diagnosis-and-treatment-of-epilepsy-in-paediatric-patients
#11
REVIEW
Davide Mei, Elena Parrini, Carla Marini, Renzo Guerrini
Next-generation sequencing (NGS) has contributed to the identification of many monogenic epilepsy syndromes and is favouring earlier and more accurate diagnosis in a subset of paediatric patients with epilepsy. The cumulative information emerging from NGS studies is rapidly changing our comprehension of the relations between early-onset severe epilepsy and the associated neurological impairment, progressively delineating specific entities previously gathered under the umbrella definition of epileptic encephalopathies, thereby influencing treatment choices and limiting the most aggressive drug regimens only to those conditions that are likely to actually benefit from them...
February 14, 2017: Molecular Diagnosis & Therapy
https://www.readbyqxmd.com/read/28160937/a-review-of-our-experience-in-phonosurgery-in-children
#12
Mikel Landa, Idoia Palicio, Leire Álvarez, Zuriñe Martínez
INTRODUCTION AND OBJECTIVES: Dysphonia is a common problem in children, especially those of school age. Exploration of vocal folds is often difficult and less accurate in children. The most frequent lesions found in children with chronic dysphonia are vocal nodules, followed by epidermoid cysts and other congenital lesions, such as sulci and mucosal bridges. The treatment is multidisciplinary and it is fundamentally based on vocal rehabilitation. We indicate surgical treatment in children older than 9 years of age for whom the problem persists after rehabilitation, especially if we suspect a congenital lesion of the vocal fold...
February 1, 2017: Acta Otorrinolaringológica Española
https://www.readbyqxmd.com/read/28148335/a-pediatric-cardiology-fellowship-boot-camp-improves-trainee-confidence
#13
Catherine K Allan, Paul Tannous, Elizabeth DeWitt, Michael Farias, Laura Mansfield, Christina Ronai, David Schidlow, Stephen P Sanders, James E Lock, Jane W Newburger, David W Brown
Introduction New paediatric cardiology trainees are required to rapidly assimilate knowledge and gain clinical skills to which they have limited or no exposure during residency. The Pediatric Cardiology Fellowship Boot Camp (PCBC) at Boston Children's Hospital was designed to provide incoming fellows with an intensive exposure to congenital cardiac pathology and a broad overview of major areas of paediatric cardiology practice. METHODS: The PCBC curriculum was designed by core faculty in cardiac pathology, echocardiography, electrophysiology, interventional cardiology, exercise physiology, and cardiac intensive care...
December 2016: Cardiology in the Young
https://www.readbyqxmd.com/read/28135773/epidemiological-study-of-paediatric-germ-cell-tumours-revealed-the-incidence-and-distribution-that-was-expected-but-a-low-mortality-rate
#14
Madeline Evers, Catherine Rechnitzer, Niels Graem, Peder Skov Wehner, Henrik Schroeder, Steen Rosthoej, Christiane Hammershaimb Mosbech, Christina Engel Hoei-Hansen, Astrid Sehested, Taryn D Treger, Jesper Brok
AIM: Germ cell tumours (GCTs) are a rare heterogeneous tumour group derived from primordial germ cells, which can be benign or malignant and occur in the gonads or extragonadally. This study mapped the paediatric GCTs in Denmark from 1984-2013 to study the incidence and outcome. METHODS: We identified paediatric GCTs from the Danish Childhood Cancer and National Pathology Registries and reviewed the case records for patient characteristics, tumour characteristics and clinical outcome...
January 30, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28127386/the-surgical-pathology-laboratory-in-mwanza-tanzania-a-survey-on-the-reproducibility-of-diagnoses-after-the-first-years-of-autonomous-activity
#15
R Tumino, P F Rambau, F Callea, L Leoncini, R Monaco, J Kahima, V Stracca Pansa, L Viberti, D Amadori, P Giovenali, K A Mteta
BACKGROUND: In 2000, an Italian non-governmental organisation (NGO) began a 9-year project to establish a surgical pathology laboratory at the Bugando Medical Centre (BMC) in Mwanza, Tanzania, a country with a low Human Development Index (HDI), and as of 2009, the laboratory was operating autonomously. The present survey aims to evaluate the reproducibility of histological and cytological diagnoses assigned in the laboratory's early years of autonomous activity. We selected a random sample of 196 histological and cytological diagnoses issued in 2010-2011 at the BMC surgical pathology laboratory...
2017: Infectious Agents and Cancer
https://www.readbyqxmd.com/read/28107788/the-indications-and-role-of-paediatric-bronchoscopy-in-a-developing-country-with-high-prevalence-of-pulmonary-tuberculosis-and-hiv
#16
Irwin Webster, Pierre Goussard, Robert Gie, Jacques Janson, Gawie Rossouw
BACKGROUND: Bronchoscopy, an important investigation for the diagnosis and management of respiratory diseases, is widely used in high income countries. There is limited information on value of paediatric bronchoscopy in low and middle income countries (LMIC). AIMS AND OBJECTIVES: Aim was to describe the indications, findings and complications of bronchoscopy in a middle income country with a high prevalence of tuberculosis and HIV. METHODOLOGY: A retrospective analysis of a database over a 3...
January 20, 2017: Expert Review of Respiratory Medicine
https://www.readbyqxmd.com/read/28091357/assessment-of-the-need-for-a-cardiac-morphology-curriculum-for-paediatric-cardiology-fellows
#17
Lindsay S Rogers, Melissa Klein, Jeanne James, Michael FitzGerald
BACKGROUND: Expert knowledge of cardiac malformations is essential for paediatric cardiologists. Current cardiac morphology fellowship teaching format, content, and nomenclature are left up to the discretion of the individual fellowship programmes. We aimed to assess practices and barriers in morphology education, perceived effectiveness of current curricula, and preferences for a standardised fellow morphology curriculum. METHODS: A web-based survey was developed de novo and administered anonymously via e-mail to all paediatric cardiology fellowship programme directors and associate directors in the United States of America; leaders were asked to forward the survey to fellows...
January 16, 2017: Cardiology in the Young
https://www.readbyqxmd.com/read/28045322/orofacial-granulomatosis-as-early-manifestation-of-crohn-s-disease-report-of-a-case-in-a-paediatric-patient
#18
A Sarra, N G Nikitakis, A Daskalopoulos, G Chouliaras, A Sklavounou-Andrikopoulou, K Athanasaki
BACKGROUND: Orofacial granulomatosis (OFG) is a controversial entity mainly characterised by recurrent or permanent soft tissue swelling of sudden onset in the orofacial area with a histologic appearance of granulomatous inflammation. Differential diagnosis includes local diseases and systemic conditions, such as Crohn's disease (CD). A case of OFG in a paediatric patient is reported here, focusing on the clinical features, diagnostic procedures, treatment and long-term outcome. CASE REPORT: A 7 year-old boy presented with persistent and prominent lip swelling and painful oral mucosa lesions of six months duration...
December 2016: European Journal of Paediatric Dentistry: Official Journal of European Academy of Paediatric Dentistry
https://www.readbyqxmd.com/read/28034440/-urothelial-tumors-in-children
#19
REVIEW
Christine Grapin-Dagorno, Matthieu Peycelon, Pascale Philippe-Chomette, Dominique Berrebi, Alaa El Ghoneimi, Daniel Orbach
Urothelial tumors are very rare in children (to date, only about 150 cases have been reported worlwide). Only 20% occur before the age of ten. The aim of this study is to specify the clinicopathologic features of urothelial tumor in young patients, which require a slightly different approach to treatment. On the basis of the WHO/ISUP (World Health Organisation/International Society of Urological Pathology) consensus classification report, these lesions are usually low-grade lesions, non invasive, and rarely recurrent...
February 2017: Bulletin du Cancer
https://www.readbyqxmd.com/read/28028858/mid-face-toddler-excoriation-syndrome-mites-a-new-paediatric-diagnosis
#20
S M Srinivas, V K Gowda, C M Owen, C Moss, R Hiremagalore
Chronic ulcerating lesions on the face are rarely seen in toddlers. Blistering disease, vasculitis, infections and self-mutilation due to neurometabolic disease can usually be excluded on clinical and histological grounds. In the absence of identifiable disease, such lesions are sometimes attributed to child abuse or fabricated illness. We describe three toddlers with chronic mid-face erosions, two from India and one from the UK. One had moderate developmental delay and one had had seizures. The lesions appeared to be self-inflicted, no underlying disease was identified and there was no suspicion of child abuse...
January 2017: Clinical and Experimental Dermatology
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