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https://www.readbyqxmd.com/read/28528596/face-and-object-perception-in-body-dysmorphic-disorder-versus-obsessive-compulsive-disorder-the-mooney-faces-task
#1
Wei Lin Toh, David J Castle, Susan L Rossell
OBJECTIVES: Body dysmorphic disorder (BDD) is characterized by repetitive behaviors and/or mental acts occurring in response to preoccupations with perceived defects or flaws in physical appearance. There are some similarities, but also important differences, between BDD and obsessive-compulsive disorder (OCD), not just in terms of core clinical symptoms, but possibly in the domain of perception. This study compared the nature and extent of perceptual anomalies in BDD versus OCD and health controls (HC), using a modified Mooney task...
May 22, 2017: Journal of the International Neuropsychological Society: JINS
https://www.readbyqxmd.com/read/28521158/degradation-of-creatinine-using-boron-doped-diamond-electrode-statistical-modeling-and-degradation-mechanism
#2
Zhefeng Zhang, Jiahui Xian, Chunyong Zhang, Degang Fu
This study investigated the degradation performance and mechanism of creatinine (a urine metabolite) with boron-doped diamond (BDD) anodes. Experiments were performed using a synthetic creatinine solution containing two supporting electrolytes (NaCl and Na2SO4). A three-level central composite design was adopted to optimize the degradation process, a mathematical model was thus constructed and used to explore the optimum operating conditions. A maximum mineralization percentage of 80% following with full creatinine removal had been achieved within 120 min of electrolysis, confirming the strong oxidation capability of BDD anodes...
May 13, 2017: Chemosphere
https://www.readbyqxmd.com/read/28504607/innate-inflammatory-gene-expression-profiling-in-potential-brain-dead-donors-detailed-investigation-of-the-effect-of-common-corticosteroid-therapy
#3
Reza Gholamnezhadjafari, Nader Tajik, Reza Falak, Reza Aflatoonian, Sanaz Dehghan, Abbas Rezaei
Our study aimed to assess the influence of common methylprednisolone therapy on innate inflammatory factors in potential brain-dead organ donors (BDDs). The study groups consisted of 50 potential BDDs who received 15 mg/kg/d methylprednisolone and 25 live organ donors (LDs) as control group. Innate immunity gene expression profiling was performed by RT-PCR array. Soluble serum cytokines and chemokines, complement components, heat shock protein 70 (HSP70) and high mobility group box-1 (HMGB1) were measured by ELISA...
January 1, 2017: Innate Immunity
https://www.readbyqxmd.com/read/28493699/electrochemical-oxidation-of-phenolic-compounds-at-boron-doped-diamond-anodes-structure-reactivity-relationships
#4
Yi Jiang, Xiuping Zhu, Xuan Xing
Electrochemical oxidation of phenolic compounds using boron-doped diamond (BDD) anodes has been shown as an effective approach to remove these contaminants from water. However, the understanding of the reaction mechanisms of substituted phenolic compounds at the BDD anode remains incomplete. In the present work, we investigated the electrochemical oxidation of 12 representative phenolic compounds (with varied substitution groups (e.g., -CH3, -OCH3, -NH2, -Cl, -OH, -COOH, -NO2, -CHO) and positions (-ortho, -meta, and -para)) at the BDD anode...
May 11, 2017: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/28482195/prevalence-of-body-dysmorphic-disorder-and-associated-features-in-german-adolescents-a-self-report-survey
#5
Anne Möllmann, Fanny A Dietel, Antje Hunger, Ulrike Buhlmann
Prior research has not yet investigated the prevalence of body dysmorphic disorder (BDD) in adolescents and young adults based on criteria from the Diagnostic and Statistical Manual of Mental Disorders, fifth edition (DSM-5). In the current study, the point prevalence of BDD, comorbid symptoms, and associated features, such as appearance-related suicidality, level of insight or history of plastic surgeries, were examined in a non-clinical sample of German adolescents and young adults (n=308), between 15 and 21 years old, using self-report measures...
April 27, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28475166/an-all-solid-state-ph-sensor-employing-fluorine-terminated-polycrystalline-boron-doped-diamond-as-a-ph-insensitive-solution-gate-field-effect-transistor
#6
Yukihiro Shintani, Mikinori Kobayashi, Hiroshi Kawarada
A fluorine-terminated polycrystalline boron-doped diamond surface is successfully employed as a pH-insensitive SGFET (solution-gate field-effect transistor) for an all-solid-state pH sensor. The fluorinated polycrystalline boron-doped diamond (BDD) channel possesses a pH-insensitivity of less than 3mV/pH compared with a pH-sensitive oxygenated channel. With differential FET (field-effect transistor) sensing, a sensitivity of 27 mv/pH was obtained in the pH range of 2-10; therefore, it demonstrated excellent performance for an all-solid-state pH sensor with a pH-sensitive oxygen-terminated polycrystalline BDD SGFET and a platinum quasi-reference electrode, respectively...
May 5, 2017: Sensors
https://www.readbyqxmd.com/read/28465327/comparing-the-curative-efficacy-of-topical-treatment-with-thiamphenicol-and-oxytetracycline-on-digital-dermatitis-lesions-in-dairy-cattle
#7
M Holzhauer, R Ploegmakers-van Deventer, D Smits, W Swart
The efficacy of two topically applied antibiotics for the treatment of painful ulcerative stage of bovine digital dermatitis (BDD) lesions was compared in a clinical trial conducted on five dairy farms in the Netherlands during the autumn of 2015. A total of 109 cows with an ulcerative (M2) stage of BDD were randomly appointed a treatment with an antibiotic-based spray. One treatment contained thiamphenicol as active ingredient (TAF). The other treatment had oxytetracycline as active ingredient (ENG). The experimental unit for this study was the hind claw with the presence of an ulcerative BDD lesion...
May 2, 2017: Veterinary Record
https://www.readbyqxmd.com/read/28438237/are-unwanted-mental-intrusions-a-transdiagnostic-variable
#8
Belén Pascual-Vera, María Roncero-Sanchís, Amparo Belloch Fuster
INTRODUCTION: Unwanted mental intrusions (UMI) constitute the normal variants of obsessions in Obsessive-Compulsive Disorder (OCD), preoccupations about defects in Body Dysmorphic Disorder (BDD), images about illness in Hypochondriasis (HYP), and thoughts about eating in Eating Disorders (EDs). We sought to investigate the relationships between frequency and discomfort associated with the experience of the four UMI contents, adopting a within-subject perspective. METHOD: A group of 438 university students and community participants (Mage= 29...
May 2017: Psicothema
https://www.readbyqxmd.com/read/28411528/anodic-oxidation-of-surfactants-and-organic-compounds-entrapped-in-micelles-selective-degradation-mechanisms-and-soil-washing-solution-reuse
#9
Clément Trellu, Nihal Oturan, Yoan Pechaud, Eric D van Hullebusch, Giovanni Esposito, Mehmet A Oturan
Formation of micelles at high surfactant concentration strongly modifies organic pollutant oxidation mechanisms and kinetics during anodic oxidation (AO) using boron doped diamond (BDD) anode. Results presented and discussed in this study emphasized the following mechanisms: (i) micelles act as a protective environment and reduce the availability of target molecules towards BDD((•)OH); (ii) the use of low current density strongly reduces micelle degradation kinetics due to both steric hindrance phenomenon for oxidation of micelles at the BDD surface and decrease of mediated oxidation in the bulk; (iii) compounds solubilized in surfactant-containing solutions can be either oxidized after degradation of the protective environment formed by micelles or if they are present as free extra-micellar compounds...
July 1, 2017: Water Research
https://www.readbyqxmd.com/read/28397397/the-structural-basis-for-the-functional-comparability-of-factor-viii-and-the-long-acting-variant-recombinant-factor-viii-fc-fusion-protein
#10
N C Leksa, P-L Chiu, G M Bou-Assaf, C Quan, Z Liu, A B Goodman, M G Chambers, S E Tsutakawa, M Hammel, R T Peters, T Walz, J D Kulman
Essentials Recombinant factor VIII (rFVIII) Fc fusion protein has a 1.5-fold longer half-life than rFVIII. Five orthogonal methods were used to characterize the structure of rFVIIIFc compared to rFVIII. The C-terminal Fc fusion does not perturb the structure of FVIII in rFVIIIFc. The FVIII and Fc components of rFVIIIFc are flexibly tethered and functionally independent. SUMMARY: Background Fusion of the human IgG1 Fc domain to the C-terminal C2 domain of B-domain-deleted (BDD) factor VIII (FVIII) results in the recombinant FVIII Fc (rFVIIIFc) fusion protein, which has a 1...
April 11, 2017: Journal of Thrombosis and Haemostasis: JTH
https://www.readbyqxmd.com/read/28367586/neurocognitive-functioning-in-young-adults-with-subclinical-body-dysmorphic-disorder
#11
Austin W Blum, Sarah A Redden, Jon E Grant
Despite reasonable knowledge of body dysmorphic disorder (BDD), little is known of its cognitive antecedents. In this study, we evaluated executive functioning and decision-making in people at risk of developing BDD using neuropsychological tests. Participants were non-treatment seeking volunteers (18-29 years) recruited from the general community, and split into two groups: those "at risk" of developing BDD (N = 5) and controls (N = 82). Participants undertook the One-Touch Stockings of Cambridge, Cambridge Gamble and Spatial Working Memory tasks and were assessed with the Body Dysmorphic Disorder Questionnaire...
April 3, 2017: Psychiatric Quarterly
https://www.readbyqxmd.com/read/28363145/removal-of-sulfamethoxazole-by-electrochemically-activated-sulfate-implications-of-chloride-addition
#12
Jelena Radjenovic, Mira Petrovic
Electrochemical oxidation is considered to be an attractive alternative to chemical oxidation for the treatment of polluted water. Given the of ability of boron-doped diamond (BDD) electrodes to generate hydroxyl radicals (OH), they are often selected for the degradation of persistent organic contaminants. Recently, BDD anodes have been demonstrated to form strong oxidants, sulfate radicals (SO4(-)), directly from sulfate ions. In this study, electrochemical activation of sulfate to SO4(-) at BDD anodes enhanced the removal of an antibiotic sulfamethoxazole (SMX)...
March 21, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/28340620/stable-high-level-expression-of-factor-viii-in-chinese-hamster-ovary-cells-in-improved-elongation-factor-1-alpha-based-system
#13
Nadezhda A Orlova, Sergey V Kovnir, Alexandre G Gabibov, Ivan I Vorobiev
BACKGROUND: Recombinant factor VIII (FVIII), used for haemophilia A therapy, is one of the most challenging among the therapeutic proteins produced in heterologous expression systems. Deletion variant of FVIII, in which the entire domain B is replaced by a short linker peptide, was approved for medical use. Efficacy and safety of this FVIII deletion variant are similar to full-length FVIII preparations while the level of production in CHO cells is substantially higher. Typical levels of productivity for CHO cell lines producing deletion variant FVIII-BDD SQ, described elsewhere, are 0...
March 24, 2017: BMC Biotechnology
https://www.readbyqxmd.com/read/28322616/how-individuals-with-body-dysmorphic-disorder-bdd-process-their-own-face-a-quantitative-and-qualitative-investigation-based-on-an-eye-tracking-paradigm
#14
Wei Lin Toh, David J Castle, Susan L Rossell
INTRODUCTION: Body dysmorphic disorder (BDD) is characterised by repetitive behaviours and/or mental acts occurring in response to preoccupations with perceived flaws in physical appearance. Based on an eye-tracking paradigm, this study aimed to examine how individuals with BDD processed their own face. METHODS: Participants were 21 BDD patients, 19 obsessive-compulsive disorder patients and 21 healthy controls (HC), who were age-, sex-, and IQ-matched. Stimuli were photographs of participants' own faces as well as those from the Pictures of Facial Affect battery...
March 21, 2017: Cognitive Neuropsychiatry
https://www.readbyqxmd.com/read/28314147/boron-doped-diamond-electrode-preparation-characterization-and-application-for-electrocatalytic-degradation-of-m-dinitrobenzene
#15
Hongmei Bai, Ping He, Jing Pan, Jingchao Chen, Yang Chen, Faqing Dong, Hong Li
Boron-doped diamond (BDD) electrode was successfully prepared via microwave plasma chemical vapor deposition method and it was used in electrocatalytic degradation of m-dinitrobenzene (m-DNB). The electrocatalytic degradation efficiency of m-DNB was evaluated under different experimental parameters including current density, temperature, pH, Na2SO4 concentration and initial m-DNB concentration. Under optimal parameters, degradation efficiency of m-DNB reached up to 82.7% after 150min. The degradation process of m-DNB was fitted well with pseudo first-order kinetics...
July 1, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28285175/patient-identified-events-implicated-in-the-development-of-body-dysmorphic-disorder
#16
Hilary Weingarden, Erin E Curley, Keith D Renshaw, Sabine Wilhelm
Little is known about the causes of body dysmorphic disorder (BDD), but researchers have proposed a diathesis-stress model. This study uses a patient-centered approach to identify stressful events to which patients attribute the development of their BDD symptoms. An Internet-recruited sample of 165 adults with BDD participated. A large minority of participants attributed the development of their BDD to a triggering event. Bullying experiences were the most commonly described type of event. Additionally, most events were interpersonal and occurred during grade school or middle school...
June 2017: Body Image
https://www.readbyqxmd.com/read/28283716/electrochemistry-coupled-online-to-liquid-chromatography-mass-spectrometry-for-fast-simulation-of-biotransformation-reactions-of-the-insecticide-chlorpyrifos
#17
Tessema F Mekonnen, Ulrich Panne, Matthias Koch
An automated method is presented for fast simulation of (bio)transformation products (TPs) of the organophosphate insecticide chlorpyrifos (CPF) based on electrochemistry coupled online to liquid chromatography-mass spectrometry (EC-LC-MS). Oxidative TPs were produced by a boron doped diamond (BDD) electrode, separated by reversed phase HPLC and online detected by electrospray ionization-mass spectrometry (ESI-MS). Furthermore, EC oxidative TPs were investigated by HPLC-tandem mass spectrometry (LC-MS/MS) and FT-ICR high resolution mass spectrometry (HRMS) and compared to in vitro assay metabolites (rat and human liver microsomes)...
March 10, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28263062/boron-doped-diamond-paste-electrodes-for-microfluidic-paper-based-analytical-devices
#18
Siriwan Nantaphol, Robert B Channon, Takeshi Kondo, Weena Siangproh, Orawon Chailapakul, Charles S Henry
Boron doped diamond (BDD) electrodes have exemplary electrochemical properties; however, widespread use of high-quality BDD has previously been limited by material cost and availability. In the present article, we report the use of a BDD paste electrode (BDDPE) coupled with microfluidic paper-based analytical devices (μPADs) to create a low-cost, high-performance electrochemical sensor. The BDDPEs are easy to prepare from a mixture of BDD powder and mineral oil and can be easily stencil-printed into a variety of electrode geometries...
March 20, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28229615/bacteremia-with-raoultella-planticola-in-the-setting-of-acute-pancreatitis-complicated-with-acute-cholangitis
#19
Esther Merino Rodríguez, Susana Rebolledo Olmedo, Joaquín Miquel Plaza
The bacterium Raoultella planticola (R planticola) is a rare pathogen in humans. We report a case of mild acute pancreatitis (MAP) of biliary origin with cholangitis and bacteremia with R planticola in association with pancreatic panniculitis (PP). A 55-year-old woman with rheumatic multiple valvulopathy presented with epigastric pain radiating to the back in a belt-like fashion for 48 hours, jaundice, choluria, acholia, and fever (38.2oC). Lab tests showed: amylase 2126 U/L, ALT 124 U/L, AST 169 U/L, GGT 3548 U/L, AP 1516 U/L, TBil 12...
February 23, 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28204935/a-review-of-body-dysmorphic-disorder-in-aesthetic-surgery-patients-and-the-legal-implications
#20
Iliana E Sweis, Jamie Spitz, David R Barry, Mimis Cohen
BACKGROUND: Body dysmorphic disorder (BDD) is an often under-recognized yet severe psychiatric illness. There is limited guidance for plastic surgeons in the USA in how to recognize and manage patients with BDD and protect themselves from potential litigation and harm. Therefore, in collaboration with legal counsel, we remind our profession of the serious nature of patients with BDD, provide warning signs for recognizing BDD, and critically evaluate the validity of informed consent and the legal ramifications of operating on such patients in the USA...
February 15, 2017: Aesthetic Plastic Surgery
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