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https://www.readbyqxmd.com/read/28438237/are-unwanted-mental-intrusions-a-transdiagnostic-variable
#1
Belén Pascual-Vera, María Roncero-Sanchís, Amparo Belloch Fuster
INTRODUCTION: Unwanted mental intrusions (UMI) constitute the normal variants of obsessions in Obsessive-Compulsive Disorder (OCD), preoccupations about defects in Body Dysmorphic Disorder (BDD), images about illness in Hypochondriasis (HYP), and thoughts about eating in Eating Disorders (EDs). We sought to investigate the relationships between frequency and discomfort associated with the experience of the four UMI contents, adopting a within-subject perspective. METHOD: A group of 438 university students and community participants (Mage= 29...
May 2017: Psicothema
https://www.readbyqxmd.com/read/28411528/anodic-oxidation-of-surfactants-and-organic-compounds-entrapped-in-micelles-selective-degradation-mechanisms-and-soil-washing-solution-reuse
#2
Clément Trellu, Nihal Oturan, Yoan Pechaud, Eric D van Hullebusch, Giovanni Esposito, Mehmet A Oturan
Formation of micelles at high surfactant concentration strongly modifies organic pollutant oxidation mechanisms and kinetics during anodic oxidation (AO) using boron doped diamond (BDD) anode. Results presented and discussed in this study emphasized the following mechanisms: (i) micelles act as a protective environment and reduce the availability of target molecules towards BDD((•)OH); (ii) the use of low current density strongly reduces micelle degradation kinetics due to both steric hindrance phenomenon for oxidation of micelles at the BDD surface and decrease of mediated oxidation in the bulk; (iii) compounds solubilized in surfactant-containing solutions can be either oxidized after degradation of the protective environment formed by micelles or if they are present as free extra-micellar compounds...
April 6, 2017: Water Research
https://www.readbyqxmd.com/read/28397397/the-structural-basis-for-the-functional-comparability-of-factor-viii-and-the-long-acting-variant-recombinant-factor-viii-fc-fusion-protein
#3
N C Leksa, P-L Chiu, G M Bou-Assaf, C Quan, Z Liu, A B Goodman, M G Chambers, S E Tsutakawa, M Hammel, R T Peters, T Walz, J D Kulman
BACKGROUND: Fusion of the human IgG1 Fc domain to the C-terminal C2 domain of B domain-deleted (BDD) factor VIII (FVIII) results in the rFVIIIFc fusion protein that has a 1.5-fold longer half-life in humans. OBJECTIVE: To assess the structural properties of rFVIIIFc by comparing its constituent FVIII and Fc elements with their respective isolated components and evaluating their structural independence within rFVIIIFc. METHODS: rFVIIIFc and its isolated FVIII and Fc components were compared by hydrogen-deuterium exchange mass spectrometry (HDX-MS)...
April 11, 2017: Journal of Thrombosis and Haemostasis: JTH
https://www.readbyqxmd.com/read/28367586/neurocognitive-functioning-in-young-adults-with-subclinical-body-dysmorphic-disorder
#4
Austin W Blum, Sarah A Redden, Jon E Grant
Despite reasonable knowledge of body dysmorphic disorder (BDD), little is known of its cognitive antecedents. In this study, we evaluated executive functioning and decision-making in people at risk of developing BDD using neuropsychological tests. Participants were non-treatment seeking volunteers (18-29 years) recruited from the general community, and split into two groups: those "at risk" of developing BDD (N = 5) and controls (N = 82). Participants undertook the One-Touch Stockings of Cambridge, Cambridge Gamble and Spatial Working Memory tasks and were assessed with the Body Dysmorphic Disorder Questionnaire...
April 3, 2017: Psychiatric Quarterly
https://www.readbyqxmd.com/read/28363145/removal-of-sulfamethoxazole-by-electrochemically-activated-sulfate-implications-of-chloride-addition
#5
Jelena Radjenovic, Mira Petrovic
Electrochemical oxidation is considered to be an attractive alternative to chemical oxidation for the treatment of polluted water. Given the of ability of boron-doped diamond (BDD) electrodes to generate hydroxyl radicals (OH), they are often selected for the degradation of persistent organic contaminants. Recently, BDD anodes have been demonstrated to form strong oxidants, sulfate radicals (SO4(-)), directly from sulfate ions. In this study, electrochemical activation of sulfate to SO4(-) at BDD anodes enhanced the removal of an antibiotic sulfamethoxazole (SMX)...
March 21, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/28340620/stable-high-level-expression-of-factor-viii-in-chinese-hamster-ovary-cells-in-improved-elongation-factor-1-alpha-based-system
#6
Nadezhda A Orlova, Sergey V Kovnir, Alexandre G Gabibov, Ivan I Vorobiev
BACKGROUND: Recombinant factor VIII (FVIII), used for haemophilia A therapy, is one of the most challenging among the therapeutic proteins produced in heterologous expression systems. Deletion variant of FVIII, in which the entire domain B is replaced by a short linker peptide, was approved for medical use. Efficacy and safety of this FVIII deletion variant are similar to full-length FVIII preparations while the level of production in CHO cells is substantially higher. Typical levels of productivity for CHO cell lines producing deletion variant FVIII-BDD SQ, described elsewhere, are 0...
March 24, 2017: BMC Biotechnology
https://www.readbyqxmd.com/read/28322616/how-individuals-with-body-dysmorphic-disorder-bdd-process-their-own-face-a-quantitative-and-qualitative-investigation-based-on-an-eye-tracking-paradigm
#7
Wei Lin Toh, David J Castle, Susan L Rossell
INTRODUCTION: Body dysmorphic disorder (BDD) is characterised by repetitive behaviours and/or mental acts occurring in response to preoccupations with perceived flaws in physical appearance. Based on an eye-tracking paradigm, this study aimed to examine how individuals with BDD processed their own face. METHODS: Participants were 21 BDD patients, 19 obsessive-compulsive disorder patients and 21 healthy controls (HC), who were age-, sex-, and IQ-matched. Stimuli were photographs of participants' own faces as well as those from the Pictures of Facial Affect battery...
March 21, 2017: Cognitive Neuropsychiatry
https://www.readbyqxmd.com/read/28314147/boron-doped-diamond-electrode-preparation-characterization-and-application-for-electrocatalytic-degradation-of-m-dinitrobenzene
#8
Hongmei Bai, Ping He, Jing Pan, Jingchao Chen, Yang Chen, Faqing Dong, Hong Li
Boron-doped diamond (BDD) electrode was successfully prepared via microwave plasma chemical vapor deposition method and it was used in electrocatalytic degradation of m-dinitrobenzene (m-DNB). The electrocatalytic degradation efficiency of m-DNB was evaluated under different experimental parameters including current density, temperature, pH, Na2SO4 concentration and initial m-DNB concentration. Under optimal parameters, degradation efficiency of m-DNB reached up to 82.7% after 150min. The degradation process of m-DNB was fitted well with pseudo first-order kinetics...
July 1, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28285175/patient-identified-events-implicated-in-the-development-of-body-dysmorphic-disorder
#9
Hilary Weingarden, Erin E Curley, Keith D Renshaw, Sabine Wilhelm
Little is known about the causes of body dysmorphic disorder (BDD), but researchers have proposed a diathesis-stress model. This study uses a patient-centered approach to identify stressful events to which patients attribute the development of their BDD symptoms. An Internet-recruited sample of 165 adults with BDD participated. A large minority of participants attributed the development of their BDD to a triggering event. Bullying experiences were the most commonly described type of event. Additionally, most events were interpersonal and occurred during grade school or middle school...
March 8, 2017: Body Image
https://www.readbyqxmd.com/read/28283716/electrochemistry-coupled-online-to-liquid-chromatography-mass-spectrometry-for-fast-simulation-of-biotransformation-reactions-of-the-insecticide-chlorpyrifos
#10
Tessema F Mekonnen, Ulrich Panne, Matthias Koch
An automated method is presented for fast simulation of (bio)transformation products (TPs) of the organophosphate insecticide chlorpyrifos (CPF) based on electrochemistry coupled online to liquid chromatography-mass spectrometry (EC-LC-MS). Oxidative TPs were produced by a boron doped diamond (BDD) electrode, separated by reversed phase HPLC and online detected by electrospray ionization-mass spectrometry (ESI-MS). Furthermore, EC oxidative TPs were investigated by HPLC-tandem mass spectrometry (LC-MS/MS) and FT-ICR high resolution mass spectrometry (HRMS) and compared to in vitro assay metabolites (rat and human liver microsomes)...
March 10, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28263062/boron-doped-diamond-paste-electrodes-for-microfluidic-paper-based-analytical-devices
#11
Siriwan Nantaphol, Robert B Channon, Takeshi Kondo, Weena Siangproh, Orawon Chailapakul, Charles S Henry
Boron doped diamond (BDD) electrodes have exemplary electrochemical properties; however, widespread use of high-quality BDD has previously been limited by material cost and availability. In the present article, we report the use of a BDD paste electrode (BDDPE) coupled with microfluidic paper-based analytical devices (μPADs) to create a low-cost, high-performance electrochemical sensor. The BDDPEs are easy to prepare from a mixture of BDD powder and mineral oil and can be easily stencil-printed into a variety of electrode geometries...
March 20, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28229615/bacteremia-with-raoultella-planticola-in-the-setting-of-acute-pancreatitis-complicated-with-acute-cholangitis
#12
Esther Merino Rodríguez, Susana Rebolledo Olmedo, Joaquín Miquel Plaza
The bacterium Raoultella planticola (R planticola) is a rare pathogen in humans. We report a case of mild acute pancreatitis (MAP) of biliary origin with cholangitis and bacteremia with R planticola in association with pancreatic panniculitis (PP). A 55-year-old woman with rheumatic multiple valvulopathy presented with epigastric pain radiating to the back in a belt-like fashion for 48 hours, jaundice, choluria, acholia, and fever (38.2oC). Lab tests showed: amylase 2126 U/L, ALT 124 U/L, AST 169 U/L, GGT 3548 U/L, AP 1516 U/L, TBil 12...
February 23, 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28204935/a-review-of-body-dysmorphic-disorder-in-aesthetic-surgery-patients-and-the-legal-implications
#13
Iliana E Sweis, Jamie Spitz, David R Barry, Mimis Cohen
BACKGROUND: Body dysmorphic disorder (BDD) is an often under-recognized yet severe psychiatric illness. There is limited guidance for plastic surgeons in the USA in how to recognize and manage patients with BDD and protect themselves from potential litigation and harm. Therefore, in collaboration with legal counsel, we remind our profession of the serious nature of patients with BDD, provide warning signs for recognizing BDD, and critically evaluate the validity of informed consent and the legal ramifications of operating on such patients in the USA...
February 15, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28199910/subthreshold-body-dysmorphic-disorder-in-adolescents-prevalence-and-impact
#14
Sophie C Schneider, Jonathan Mond, Cynthia M Turner, Jennifer L Hudson
The aim of the current study was to establish the prevalence of subthreshold body dysmorphic disorder (subthreshold-BDD) in a community sample of adolescents, and to compare disorder correlates in individuals with subthreshold-BDD to those with probable full-syndrome BDD (probable-BDD) and those without BDD (non-BDD). Self-report questionnaires assessing DSM-IV BDD criteria, past mental health service use, and symptoms of body dysmorphic disorder, anxiety, depression, obsessive-compulsive disorder and eating disorders, were completed by 3149 Australian high school students (mean age =14...
May 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28192945/probing-electrode-heterogeneity-using-fourier-transformed-alternating-current-voltammetry-application-to-a-dual-electrode-configuration
#15
Sze-Yin Tan, Patrick R Unwin, Julie V Macpherson, Jie Zhang, Alan M Bond
Quantitative studies of electron transfer processes at electrode/electrolyte interfaces, originally developed for homogeneous liquid mercury or metallic electrodes, are difficult to adapt to the spatially heterogeneous nanostructured electrode materials that are now commonly used in modern electrochemistry. In this study, the impact of surface heterogeneity on Fourier-transformed alternating current voltammetry (FTACV) has been investigated theoretically under the simplest possible conditions where no overlap of diffusion layers occurs and where numerical simulations based on a 1D diffusion model are sufficient to describe the mass transport problem...
February 13, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28182974/diamond-based-electrochemical-aptasensor-realizing-a-femtomolar-detection-limit-of-bisphenol-a
#16
Yibo Ma, Junsong Liu, Hongdong Li
In this study, we designed and fabricated an electrochemical impedance aptasensor based on Au nanoparticles (Au-NPs) coated boron-doped diamond (BDD) modified with aptamers, and 6-mercapto-1-hexanol (MCH) for the detection of bisphenol A (BPA). The constructed BPA aptasensor exhibits good linearity from 1.0×10(-14) to 1.0×10(-9)molL(-1). The detection limitation of 7.2×10(-15)molL(-1) was achieved, which can be attributed to the synergistic effect of combining BDD with Au-NPs, aptamers, and MCH. The examine results of BPA traces in Tris-HCl buffer and in milk, UV spectra of aptamer/BPA and interference test revealed that the novel aptasensors are of high sensitivity, specificity, stability and repeatability, which could be promising in practical applications...
June 15, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28179046/medium-and-long-term-prognostic-validity-of-competing-classification-proposals-for-the-former-somatoform-disorders
#17
S Schumacher, W Rief, K Klaus, E Brähler, R Mewes
BACKGROUND: DSM-5 introduced a fundamental revision of the category of somatoform disorders, which resulted in the new somatic symptom disorder (SSD) and related disorders. However, prognostic validity of SSD remains unclear, while other classification proposals, such as bodily distress disorder (BDD) or polysymptomatic distress disorder (PSDD), might be promising alternatives for the new ICD-11. Therefore, the comparison of the different approaches concerning long-term prognosis of disorder-relevant factors is of special interest...
February 9, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28167328/attentional-biases-in-body-dysmorphic-disorder-bdd-eye-tracking-using-the-emotional-stroop-task
#18
Wei Lin Toh, David J Castle, Susan L Rossell
OBJECTIVE: Body dysmorphic disorder (BDD) is characterised by repetitive behaviours and/or mental acts occurring in response to preoccupations with perceived defects or flaws in physical appearance. This study aimed to examine attentional biases in BDD via the emotional Stroop task with two modifications: i) incorporating an eye-tracking paradigm, and ii) employing an obsessive-compulsive disorder (OCD) control group. METHOD: Twenty-one BDD, 19 OCD and 21 HC participants, who were age-, sex-, and IQ-matched, were included...
January 23, 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/28157603/efficient-treatment-of-perfluorohexanoic-acid-by-nanofiltration-followed-by-electrochemical-degradation-of-the-nf-concentrate
#19
Álvaro Soriano, Daniel Gorri, Ane Urtiaga
The present study was aimed at the development of a strategy for removing and degrading perfluorohexanoic acid (PFHxA) from industrial process waters at concentrations in the range 60-200 mg L(-1). The treatment train consisted of nanofiltration (NF) separation followed by electrochemical degradation of the NF concentrate. Using a laboratory-scale system and working in the total recirculation mode, the DowFilm NF270 membrane provided PFHxA rejections that varied in the range 96.6-99.4% as the operating pressure was increased from 2...
January 25, 2017: Water Research
https://www.readbyqxmd.com/read/28141632/body-dysmorphic-obsessive-compulsive-and-social-anxiety-disorder-beliefs-as-predictors-of-in-vivo-stressor-responding
#20
E Marie Parsons, Kelsey T Straub, April R Smith, Elise M Clerkin
This study tested the potential transdiagnostic nature of body dysmorphic disorder (BDD), obsessive-compulsive disorder (OCD), and social anxiety disorder (SAD) beliefs, in addition to testing the specificity of those beliefs, in predicting how individuals responded to symptom-specific stressors. Participants included 127 adults (75% women) with a broad range of symptom severity. Path analysis was used to evaluate whether specific maladaptive beliefs predicted distress in response to symptom-relevant stressors over and above other beliefs and baseline distress...
January 30, 2017: Journal of Nervous and Mental Disease
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