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Exercise echocardiography

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https://www.readbyqxmd.com/read/28206674/effects-of-spinal-cord-stimulation-on-cardiac-sympathetic-nerve-activity-in-patients-with-heart-failure
#1
Jan Naar, Deborah Jaye, Cecilia Linde, Petr Neužil, Petr Doškář, Filip Málek, Frieder Braunschweig, Lars H Lund, Lars Mortensen, Bengt Linderoth, Göran Lind, Dianna Bone, Arthur J Scholte, Fred Kueffer, Jodi Koehler, Kambiz Shahgaldi, Otto Lang, Marcus Ståhlberg
BACKGROUND: Spinal cord stimulation (SCS) reduces sympathetic activity in animal models of heart failure with reduced ejection fraction (HF) but limited data exist of SCS in patients with HF. The aim of the present study was to test the primary hypothesis that SCS reduces cardiac sympathetic nerve activity in HF patients. Secondary hypotheses were that SCS improves left ventricular function and dimension, exercise capacity and clinical variables relevant to HF. METHODS: HF patients with a SCS device previously participating in the DEFEAT-HF trial were included in this crossover study with 6-week intervention periods (SCS-ON and SCS-OFF)...
February 16, 2017: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/28198075/exercise-induced-b-lines-identify-worse-functional-and-prognostic-stage-in-heart-failure-patients-with-depressed-left-ventricular-ejection-fraction
#2
Maria Chiara Scali, Lauro Cortigiani, Anca Simionuc, Dario Gregori, Mario Marzilli, Eugenio Picano
AIMS: Exercise stress echocardiography (ESE) is recommended by the European Society of Cardiology guidelines for the evaluation of heart failure (HF) patients. Recently, lung ultrasound (LUS) has been proposed for the assessment of extravascular lung water through B-lines. The aim of this study was to assess B-lines during ESE in HF. METHODS AND RESULTS: Standard transthoracic and LUS evaluation was performed during semi-supine ESE in 103 NYHA class I-III HF patients (76 male; mean age 64 ± 12 years) with depressed LVEF (35 ± 8%)...
February 15, 2017: European Journal of Heart Failure
https://www.readbyqxmd.com/read/28196853/impaired-cardiac-and-skeletal-muscle-bioenergetics-in-children-adolescents-and-young-adults-with-barth-syndrome
#3
Adil Bashir, Kathryn L Bohnert, Dominic N Reeds, Linda R Peterson, Adam J Bittel, Lisa de Las Fuentes, Christina A Pacak, Barry J Byrne, W Todd Cade
: Barth syndrome (BTHS) is an X-linked condition characterized by altered cardiolipin metabolism and cardioskeletal myopathy. We sought to compare cardiac and skeletal muscle bioenergetics in children, adolescents, and young adults with BTHS and unaffected controls and examine their relationships with cardiac function and exercise capacity. Children/adolescents and young adults with BTHS (n = 20) and children/adolescent and young adult control participants (n = 23, total n = 43) underwent (31)P magnetic resonance spectroscopy ((31)P-MRS) of the lower extremity (calf) and heart for estimation of skeletal muscle and cardiac bioenergetics...
February 2017: Physiological Reports
https://www.readbyqxmd.com/read/28188951/the-influence-of-adrenergic-stimulation-on-sex-differences-in-left-ventricular-twist-mechanics
#4
Alexandra M Williams, Rob E Shave, William S Cheyne, Neil D Eves
BACKGROUND: Sex differences in LV mechanics exist at rest and during acute physiological stress. Differences in cardiac autonomic and adrenergic control may contribute to sex differences in LV mechanics and LV hemodynamics. Accordingly, this study aimed to investigate sex differences in LV mechanics with altered adrenergic stimulation achieved through post handgrip exercise ischemia (PEI) and β1 -adrenergic receptor (AR) blockade. METHODS AND RESULTS: 20 males (23 ± 5 yr) and 20 females (22 ± 3 yr) were specifically matched for LV length (males: 8...
February 11, 2017: Journal of Physiology
https://www.readbyqxmd.com/read/28187374/the-strengths-and-weaknesses-of-non-invasive-parameters-obtained-by-echocardiography-and-cardiopulmonary-exercise-testing-in-comparison-with-the-hemodynamic-assessment-by-the-right-heart-catheterization-in-patients-with-pulmonary-hypertension
#5
Katarzyna Ptaszyńska-Kopczyńska, Anna Krentowska, Emilia Sawicka, Anna Skoneczny, Małgorzata Jasiewicz, Małgorzata Knapp, Włodzimierz J Musiał, Bożena Sobkowicz, Karol A Kamiński
PURPOSE: Pulmonary hypertension (PH) diagnosis requires invasive assessment by right heart catheterization (RHC), but screening and monitoring are performed using non-invasive methods: echocardiography and cardiopulmonary exercise testing (CPET). The aim of the study was to assess correlations between the parameters obtained in non-invasive testing and RHC in patients with PH of different etiologies. MATERIAL/METHODS: The study included 53 medical records of PH patients (32 women) aged 29-81 years...
June 14, 2016: Advances in Medical Sciences
https://www.readbyqxmd.com/read/28184260/perioperative-management-of-left-ventricular-diastolic-dysfunction-and-heart-failure-an-anesthesiologist-s-perspective
#6
REVIEW
Taeha Ryu, Seok-Young Song
Anesthesiologists frequently see asymptomatic patients with diastolic dysfunction or heart failure for various surgeries. These patients typically show normal systolic function but abnormal diastolic parameters in their preoperative echocardiographic evaluations. The symptoms that are sometimes seen are similar to those of chronic obstructive pulmonary disease. Patients with diastolic dysfunction, and even with diastolic heart failure, have the potential to develop a hypertensive crisis or pulmonary congestion...
February 2017: Korean Journal of Anesthesiology
https://www.readbyqxmd.com/read/28183533/chronic-embolic-pulmonary-hypertension-caused-by-pulmonary-embolism-and-vascular-endothelial-growth-factor-inhibition
#7
Evandro M Neto-Neves, Mary Beth Brown, Maria V Zaretskaia, Samin Rezania, Adam G Goodwill, Brian P McCarthy, Scott A Persohn, Paul R Territo, Jeffrey A Kline
Our understanding of the pathophysiological basis of chronic thromboembolic pulmonary hypertension (CTEPH) will be accelerated by an animal model that replicates the phenotype of human CTEPH. Sprague-Dawley rats were administered a combination of a single dose each of plastic microspheres and vascular endothelial growth factor receptor antagonist in polystyrene microspheres (PE) + tyrosine kinase inhibitor SU5416 (SU) group. Shams received volume-matched saline; PE and SU groups received only microspheres or SU5416, respectively...
February 6, 2017: American Journal of Pathology
https://www.readbyqxmd.com/read/28181133/effects-of-aerobic-exercise-training-on-metabolism-of-nitric-oxide-and-endothelin-1-in-lung-parenchyma-of-rats-with-pulmonary-arterial-hypertension
#8
A Zimmer, R B Teixeira, J H P Bonetto, R Siqueira, C C Carraro, L M Donatti, A Hickmann, I E Litvin, A E G Godoy, A S Araujo, R Colombo, Adriane Belló-Klein
Pulmonary arterial hypertension (PAH) is characterized by vasoconstriction and proliferative obstruction of pulmonary vessels, which promotes a progressive increase in pulmonary vascular resistance (PVR). The effect of exercise training on oxidative stress, metabolism, and markers of nitric oxide (NO) and endothelin-1 (ET-1) was analyzed in the lung tissue of rats with PAH induced by monocrotaline (MCT).Twenty-four Wistar rats were divided into four groups (5-7 animals): sedentary control (SC), sedentary MCT (SM), trained control (TC), and trained MCT (TM)...
February 8, 2017: Molecular and Cellular Biochemistry
https://www.readbyqxmd.com/read/28176968/decreased-left-ventricular-stroke-volume-is-associated-with-low-grade-exercise-tolerance-in-patients-with-chronic-obstructive-pulmonary-disease
#9
Sumito Inoue, Yoko Shibata, Hiroyuki Kishi, Joji Nitobe, Tadateru Iwayama, Yoshinori Yashiro, Takako Nemoto, Kento Sato, Masamichi Sato, Tomomi Kimura, Akira Igarashi, Yoshikane Tokairin, Isao Kubota
BACKGROUND: Low-grade exercise tolerance is associated with a poor prognosis in patients with chronic obstructive pulmonary disease (COPD). The 6 min walk test (6MWT) is commonly used to evaluate exercise tolerance in patients with COPD. However, little is known regarding the relationship between cardiac function and exercise tolerance in patients with COPD. The aim of this study was to identify predictive factors in cardiac function for low-grade exercise tolerance in patients with stable COPD...
2017: BMJ Open Respiratory Research
https://www.readbyqxmd.com/read/28155245/scriptaid-enhances-skeletal-muscle-insulin-action-and-cardiac-function-in-obese-mice
#10
Vidhi Gaur, Timothy Connor, Kylie Venardos, Darren C Henstridge, Sheree D Martin, Courtney Swinton, Shona Morrison, Kathryn Aston-Mourney, Stefan M Gehrig, Roelof van Ewijk, Gordon S Lynch, Mark A Febbraio, Gregory R Steinberg, Mark Hargreaves, Ken R Walder, Sean L McGee
AIMS/HYPOTHESIS: Current drugs used to treat metabolic diseases such as obesity and type 2 diabetes have limited efficacy in directly normalising muscle insulin action, while exercise is effective in enhancing this aspect of metabolic disease. We recently identified Scriptaid as a compound that can replicate aspects of the exercise adaptive response, through disruption of the class IIa HDAC corepressor complex. The Aim of this study was to determine the effect of Scriptaid on muscle insulin action in obesity...
February 2, 2017: Diabetes, Obesity & Metabolism
https://www.readbyqxmd.com/read/28150069/influence-of-gender-on-right-ventricle-adaptation-to-endurance-exercise-an-ultrasound-two-dimensional-speckle-tracking-stress-study
#11
Maria Sanz-de la Garza, Geneviève Giraldeau, Josefa Marin, Gonzalo Grazioli, Montserrat Esteve, Luigi Gabrielli, Carlos Brambila, Laura Sanchis, Bart Bijnens, Marta Sitges
BACKGROUND: Characteristic right ventricle (RV) remodelling is related to endurance exercise in male athletes (MAs), but data in female athletes (FAs) are scarce. Our aim was to evaluate sex-related influence on exercise-induced RV remodelling and on RV performance during exercise. METHODS: Forty endurance athletes (>10 training hours/week, 50% female) and 40 age-matched controls (<3 h moderate exercise/week, 50% female) were included. Echocardiography was performed at rest and at maximum cycle-ergometer effort...
February 1, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28149413/left-atrial-enlargement-in-young-high-level-endurance-athletes-another-sign-of-athlete-s-heart
#12
Wojciech Król, Ilona Jędrzejewska, Marcin Konopka, Krystyna Burkhard-Jagodzińska, Andrzej Klusiewicz, Andrzej Pokrywka, Jolanta Chwalbińska, Dariusz Sitkowski, Mirosław Dłużniewski, Artur Mamcarz, Wojciech Braksator
Enlargement of the left atrium is perceived as a part of athlete's heart syndrome, despite the lack of evidence. So far, left atrial size has not been assessed in the context of exercise capacity. The hypothesis of the present study was that LA enlargement in athletes was physiological and fitness-related condition. In addition, we tried to assess the feasibility and normal values of left atrial strain parameters and their relationship with other signs of athlete's heart. The study group consisted of 114 international-level rowers (17...
December 1, 2016: Journal of Human Kinetics
https://www.readbyqxmd.com/read/28148335/a-pediatric-cardiology-fellowship-boot-camp-improves-trainee-confidence
#13
Catherine K Allan, Paul Tannous, Elizabeth DeWitt, Michael Farias, Laura Mansfield, Christina Ronai, David Schidlow, Stephen P Sanders, James E Lock, Jane W Newburger, David W Brown
: Introduction New paediatric cardiology trainees are required to rapidly assimilate knowledge and gain clinical skills to which they have limited or no exposure during residency. The Pediatric Cardiology Fellowship Boot Camp (PCBC) at Boston Children's Hospital was designed to provide incoming fellows with an intensive exposure to congenital cardiac pathology and a broad overview of major areas of paediatric cardiology practice. METHODS: The PCBC curriculum was designed by core faculty in cardiac pathology, echocardiography, electrophysiology, interventional cardiology, exercise physiology, and cardiac intensive care...
December 2016: Cardiology in the Young
https://www.readbyqxmd.com/read/28145667/acute-coronary-syndrome-diagnostic-evaluation
#14
Craig Barstow, Matthew Rice, Jonathan D McDivitt
Myocardial infarction (MI), a subset of acute coronary syndrome, is damage to the cardiac muscle as evidenced by elevated cardiac troponin levels in the setting of acute ischemia. Coronary artery disease is the leading cause of mortality in the United States. Chest pain is a common presentation in patients with MI; however, there are multiple noncardiac causes of chest pain, and the diagnosis cannot always be made based on initial presentation. The assessment of a possible MI includes evaluation of risk factors and presenting signs and symptoms, rapid electrocardiography, and serum cardiac troponin measurements...
February 1, 2017: American Family Physician
https://www.readbyqxmd.com/read/28132404/right-ventricular-function-during-acute-exacerbation-of-severe-equine-asthma
#15
A Decloedt, H Borowicz, M Slowikowska, K Chiers, G van Loon, A Niedzwiedz
BACKGROUND: Pulmonary hypertension has been described in horses with severe equine asthma but its effect on the right ventricle has not been fully elucidated. OBJECTIVES: To evaluate right ventricular structure and function after a one-week period of pulmonary hypertension secondary to acute exacerbation of severe equine asthma. STUDY DESIGN: Prospective study. METHODS: A clinical episode of severe equine asthma was induced experimentally in six susceptible horses...
January 28, 2017: Equine Veterinary Journal
https://www.readbyqxmd.com/read/28131566/functional-outcome-in-chronic-heart-failure-after-exercise-training-possible-predictive-value-of-heart-rate-variability
#16
Roberto Ricca-Mallada, Edurado R Migliaro, Gabriela Silvera, Lilian Chiappella, Rossana Frattini, Federico Ferrando-Castagnetto
BACKGROUND: Controlled exercise training (ET) is a valuable therapeutic addition to pharmacological treatment in most patients with chronic heart failure (CHF), reducing long-term mortality, preventing cardiac remodelling and improving functional capacity. Despite the fact that the mechanism underlying its benefits might be multifactorial, a sustained improvement in autonomic balance is usually attributed as a major effect. Nevertheless, not all eligible subjects show the same response to ET, probably due to several differences in the subpopulations enrolled...
January 25, 2017: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/28117249/downhill-exercise-training-in-monocrotaline-injected-rats-effects-on-echocardiographic-and-haemodynamic-variables-and-survival
#17
Irina Enache, Fabrice Favret, Stéphane Doutreleau, Paola Goette Di Marco, Anne-Laure Charles, Bernard Geny, Anne Charloux
BACKGROUND: Eccentric exercise training has been shown to improve muscle force strength without excessive cardiovascular stress. Such an exercise modality deserves to be tested in pulmonary arterial hypertension. AIM: We aimed to assess the effects of an eccentric training modality on cardiac function and survival in an experimental monocrotaline-induced model of pulmonary arterial hypertension with right ventricular dysfunction. METHODS: Forty rats were randomly assigned to one of four groups: 40mg/kg monocrotaline-injected sedentary rats; 40mg/kg monocrotaline-injected eccentric-trained rats; sedentary control rats; or eccentric-trained control rats...
January 20, 2017: Archives of Cardiovascular Diseases
https://www.readbyqxmd.com/read/28110909/relationship-between-carotid-intima-media-thickness-and-the-results-of-exercise-echocardiography-in-patients-with-suspected-coronary-disease
#18
Ramón Rubio Patón, María Isabel Pacheco Tenza, Enrique Bernal Morell, Juan Carlos Bonaque González, Rosa María Soto Ruiz, Juan Antonio Castillo Moreno
No abstract text is available yet for this article.
January 16, 2017: Revista Española de Cardiología
https://www.readbyqxmd.com/read/28107887/associations-between-positive-emotional-well-being-and-stress-induced-myocardial-ischemia-well-being-scores-predict-exercise-induced-ischemia
#19
Jacob P Feigal, Stephen H Boyle, Zainab Samad, Eric J Velazquez, Jennifer L Wilson, Richard C Becker, Redford B Williams, Cynthia M Kuhn, Thomas L Ortel, Joseph G Rogers, Christopher M O'Connor, Wei Jiang
OBJECTIVE: Depressive symptoms have been associated with myocardial ischemia induced by mental (MSIMI) and exercise (ESIMI) stress in clinically stable ischemic heart disease (IHD) patients, but the association between positive emotions and inducible ischemia is less well characterized. The objective of this study was to examine the associations between ratings of well-being and stress-induced ischemia. METHODS: Subjects were adult patients with documented IHD underwent mental and exercise stress testing for the Responses of Myocardial Ischemia to Escitalopram Treatment (REMIT) trial...
February 2017: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/28100544/oscillatory-whole-body-vibration-improves-exercise-capacity-and-physical-performance-in-pulmonary-arterial-hypertension-a-randomised-clinical-study
#20
Felix Gerhardt, Daniel Dumitrescu, Carina Gärtner, Ralf Beccard, Thomas Viethen, Tilmann Kramer, Stephan Baldus, Martin Hellmich, Eckhard Schönau, Stephan Rosenkranz
OBJECTIVE: In patients with pulmonary arterial hypertension (PAH), supportive therapies may be beneficial in addition to targeted medical treatment. Here, we evaluated the effectiveness and safety of oscillatory whole-body vibration (WBV) in patients on stable PAH therapy. METHODS: Twenty-two patients with PAH (mean PAP≥25 mm Hg and pulmonary arterial wedge pressure (PAWP)≤15 mm Hg) who were in world health organization (WHO)-Functional Class II or III and on stable PAH therapy for≥3 months, were randomised to receive WBV (16 sessions of 1-hour duration within 4 weeks) or to a control group, that subsequently received WBV...
January 18, 2017: Heart: Official Journal of the British Cardiac Society
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