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Exercise echocardiography

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https://www.readbyqxmd.com/read/28542926/effect-of-spironolactone-on-exercise-tolerance-and-arterial-function-in-older-adults-with-heart-failure-with-preserved-ejection-fraction
#1
Bharathi Upadhya, William G Hundley, Peter H Brubaker, Timothy M Morgan, Kathryn P Stewart, Dalane W Kitzman
OBJECTIVES: To evaluate the effects of an aldosterone antagonist on exercise intolerance in older adults with heart failure and preserved ejection fraction (HFpEF). DESIGN: Randomized, placebo-controlled, double-blind trial. SETTING: Academic medical center, Winston-Salem, North Carolina. PARTICIPANTS: Older adults (N = 80, aged 71 ± 1; 80% female) with stable compensated HFpEF and controlled blood pressure (BP)...
May 19, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28536067/relationship-between-quantitative-and-descriptive-methods-of-studying-blood-flow-through-intrapulmonary-arteriovenous-anastomoses-during-exercise
#2
Joseph W Duke, Jonathan E Elliott, Steven S Laurie, Thomas Voelkel, Igor M Gladstone, Mathews B Fish, Andrew T Lovering
Several methods exist to study intrapulmonary arteriovenous anastomoses (IPAVA) in humans. Transthoracic saline contrast echocardiography (TTSCE), i.e., bubble scores, is minimally-invasive, but cannot be used to quantify the magnitude of blood flow through IPAVA (QIPAVA). Radiolabeled macroaggregates of albumin ((99m)Tc-MAA) have been used to quantify QIPAVA in humans, but this requires injection of radioactive particles. Previous work has shown agreement between (99m)Tc-MAA and TTSCE, but this has not been tested simultaneously in the same group of subjects...
May 20, 2017: Respiratory Physiology & Neurobiology
https://www.readbyqxmd.com/read/28516519/exercise-training-in-diastolic-heart-failure-ex-dhf-rationale-and-design-of-a-multicentre-prospective-randomized-controlled-parallel-group-trial
#3
Frank Edelmann, Anna Bobenko, Götz Gelbrich, Gerd Hasenfuss, Christoph Herrmann-Lingen, André Duvinage, Silja Schwarz, Meinhard Mende, Christiane Prettin, Tobias Trippel, Ruhdja Lindhorst, Daniel Morris, Elisabeth Pieske-Kraigher, Kathleen Nolte, Hans-Dirk Düngen, Rolf Wachter, Martin Halle, Burkert Pieske
Heart failure with preserved ejection fraction (HFpEF) is a common disease with high incidence and increasing prevalence. Patients suffer from functional limitation, poor health-related quality of life, and reduced prognosis. A pilot study in a smaller group of HFpEF patients showed that structured, supervised exercise training (ET) improves maximal exercise capacity, diastolic function, and physical quality of life. However, the long-term effects of ET on patient-related outcomes remain unclear in HFpEF. The primary objective of the Exercise training in Diastolic Heart Failure (Ex-DHF) trial is to investigate whether a 12 month supervised ET can improve a clinically meaningful composite outcome score in HFpEF patients...
May 17, 2017: European Journal of Heart Failure
https://www.readbyqxmd.com/read/28515695/chronic-endurance-exercise-impairs-cardiac-structure-and-function-in-middle-aged-mice-with-impaired-nrf2-signaling
#4
Gobinath Shanmugam, Madhusudhanan Narasimhan, Robbie L Conley, Thiagarajan Sairam, Ashutosh Kumar, Ronald P Mason, Ramalingam Sankaran, John R Hoidal, Namakkal S Rajasekaran
Nuclear factor erythroid 2 related factor 2 (Nrf2) signaling maintains the redox homeostasis and its activation is shown to suppress cardiac maladaptation. Earlier we reported that acute endurance exercise (2 days) evoked antioxidant cytoprotection in young WT animals but not in aged WT animals. However, the effect of repeated endurance exercise during biologic aging (WT) characterized by an inherent deterioration in Nrf2 signaling and pathological aging (pronounced oxidative susceptibility-Nrf2 absence) in the myocardium remains elusive...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28514395/-impact-of-shock-wave-therapy-on-the-clinical-and-functional-status-of-patients-with-coronary-heart-disease
#5
S T Matskeplishvili, B M Borbodoeva, E U Asymbekova, A Z Rakhimov, N K Akhmedyarova, K B Kataeva, Yu I Buziashvili
AIM: To study of the impact of shock-wave therapy (SWT) on the functional status of patients with coronary heart disease (CHD). SUBJECTS AND METHODS: Thirty-four CHD patients (including 33 men) with left ventricular (LV) asynergic segments, as evidenced by echocardiography (EchoCG), were examined. Their mean age was 60.1±1.76 years. All the patients received a SWT cycle according to the standard scheme. The patient examination protocol involved EchoCG, dobutamine EchoCG, treadmill exercise EchoCG, and tissue Doppler EchoCG, which were performed at baseline, immediately and one month after the end of a SWT cycle...
2017: Terapevticheskiĭ Arkhiv
https://www.readbyqxmd.com/read/28514266/pulmonary-vascular-function-and-aerobic-exercise-capacityat-moderate-altitude
#6
Vitalie Faoro, Gael Deboeck, Marco Vicenzi, Anne-Fleur Gaston, Bamodi Simaga, Grégory Doucende, Ilona Hapkova, Emma Roca, Enric Subirats, Fabienne Durand, Robert Naeije
PURPOSE: There has been suggestion that a greater "pulmonary vascular reserve" defined by a low pulmonary vascular resistance (PVR) and a high lung diffusing capacity (DL) allows for a superior aerobic exercise capacity. How pulmonary vascular reserve might affect exercise capacity at moderate altitude is not known. METHODS: Thirty-eight healthy subjects underwent an exercise stress echocardiography of the pulmonary circulation, combined with measurements of DL for nitric oxide (NO) and carbon monoxide (CO) and a cardio-pulmonary exercise test at sea level and at the altitude of 2250m...
May 17, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28511954/high-intensity-interval-training-hiit-improves-resting-blood-pressure-metabolic-met-capacity-and-heart-rate-reserve-without-compromising-resting-myocardial-function-in-sedentary-aging-men
#7
Fergal M Grace, Peter Herbert, Adrian D Elliott, Jo Richards, Alexander Beaumont, Nicholas F Sculthorpe
BACKGROUND: This study examined the combination of pre-conditioning exercise with subsequent high intensity interval training (HIIT) on blood pressure, echocardiography, cardiac strain mechanics and maximal metabolic (MET) capacity in sedentary (SED) aging men compared with age matched masters athletes (LEX). METHODS: Using a STROBE compliant observational design, 39 aging male participants (SED; n=22, aged 62.7±5.2yrs) (LEX; n=17, aged=61.1±5.4yrs) were recruited to a study that necessitated three distinct assessment phases; enrolment (Phase A), following pre-conditioning exercise in SED (Phase B), then following 6weeks of HIIT performed once every five days by both groups before reassessment (Phase C)...
May 13, 2017: Experimental Gerontology
https://www.readbyqxmd.com/read/28508510/impaired-atrioventricular-transport-in-patients-with-transposition-of-the-great-arteries-palliated-by-atrial-switch-and-preserved-systolic-right-ventricular-function-a-magnetic-resonance-imaging-study
#8
Magalie Ladouceur, Nadjia Kachenoura, Gilles Soulat, Emilie Bollache, Alban Redheuil, Michel Azizi, Christophe Delclaux, Gilles Chatellier, Pierre Boutouyrie, Laurence Iserin, Damien Bonnet, Elie Mousseaux
OBJECTIVES: We aimed (1) determine if systemic right ventricle filling parameters influence systemic right ventricle stroke volume in adult patients with D-transposition of the great arteries (D-TGA) palliated by atrial switch, using cardiac magnetic resonance imaging and echocardiography, and (2) to study relationship of these diastolic parameters with exercise performance and BNP, in patients with preserved systolic systemic right ventricle function. DESIGN: Single-center, cross-sectional, prospective study...
May 16, 2017: Congenital Heart Disease
https://www.readbyqxmd.com/read/28507438/pulmonary-hypertension-in-nigerian-adults-with-sickle-cell-anemia
#9
Valentine N Amadi, Michael O Balogun, Norah O Akinola, Rasaaq A Adebayo, Anthony O Akintomide
BACKGROUND: Sickle cell anemia (SCA) is the commonest hemoglobinopathy and is associated with high morbidity and mortality. Pulmonary hypertension (PH) is reported to play a significant role in this regard. There is very limited literature on PH in SCA in Nigeria. OBJECTIVES: The objectives of this study were to determine the prevalence of Doppler-derived PH in SCA, assess its influence on exercise capacity, and determine the correlates and predictors of measures of estimated pulmonary pressure...
2017: Vascular Health and Risk Management
https://www.readbyqxmd.com/read/28501918/exercise-stress-echocardiography-in-hypertrophic-cardiomyopathy
#10
Kengo Suzuki, Yoshihiro J Akashi
In this review, we make a comprehensive summary of exercise stress echocardiography in hypertrophic cardiomyopathy (HCM) and practical tips used in our hospital. The main objective of performing exercise stress echocardiography in patients with HCM is to evaluate left ventricular outflow tract obstruction, mitral regurgitation, left ventricular asynergy, and diastolic function during exercise. There are limitations to the explanations that can be provided for exertional symptoms when resting echocardiography is performed in patients with HCM...
May 13, 2017: Journal of Echocardiography
https://www.readbyqxmd.com/read/28499844/inconclusive-exercise-stress-echocardiography-in-patients-with-chest-pain-prevalence-and-clinical-determinants
#11
Pedro J Flores-Blanco, Francisco Cambronero, Miguel García-Navarro, Gonzalo de la Morena, Mariano Valdés, Sergio Manzano-Fernández
No abstract text is available yet for this article.
May 9, 2017: Revista Española de Cardiología
https://www.readbyqxmd.com/read/28496079/-surgical-treatment-for-anomalous-aortic-origin-of-coronary-arteries
#12
Ryo Hirayama, Ryusuke Suzuki, Toshiaki Watanabe, Mai Matsukawa, Takeshi Sakaguchi, Kenta Uekihara, Yuki Yoshioka, Masaharu Mouri, Tomoya Miyamoto, Masamichi Nakajima
Anomalous aortic origin of coronary arteries is rare. We report 3 cases of surgical treatment for anomalous aortic origin of coronary arteries. Case 1 was a 38-year-old man who was saved by the use of an automated external defibrillator from cardiopulmonary arrest while exercising. The coronary angiogram showed the right coronary artery arising from the left coronary sinus of Valsalva and being located between the aorta and the pulmonary trunk. He underwent coronary artery bypass grafting (CABG) using the right internal thoracic artery with ligation of proximal part of right coronary artery to prevent sudden death...
May 2017: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/28493475/change-of-left-ventricular-rigid-body-rotation-during-dipyridamole-induced-vasodilation-a-case-from-the-three-dimensional-speckle-tracking-echocardiographic-magyar-stress-study
#13
Attila Nemes, Gyula Szántó, Péter Domsik, Árpád Kormányos, Anita Kalapos, Nóra Ambrus, Tamás Forster
A patient with previous coronary stenting presented with stable angina and positive exercise treadmill test. Echocardiography with three-dimensional speckle-tracking demonstrated left ventricular rigid body rotation (near absence of left ventricular twist), whose characteristics changed dramatically during dipyridamole-induced vasodilatation. © 2017 Wiley Periodicals, Inc. J Clin Ultrasound, 2017.
May 11, 2017: Journal of Clinical Ultrasound: JCU
https://www.readbyqxmd.com/read/28473401/ranolazine-in-symptomatic-diabetic-patients-without-obstructive-coronary-artery-disease-impact-on-microvascular-and-diastolic-function
#14
Nishant R Shah, Michael K Cheezum, Vikas Veeranna, Stephen J Horgan, Viviany R Taqueti, Venkatesh L Murthy, Courtney Foster, Jon Hainer, Karla M Daniels, Jose Rivero, Amil M Shah, Peter H Stone, David A Morrow, Michael L Steigner, Sharmila Dorbala, Ron Blankstein, Marcelo F Di Carli
BACKGROUND: Treatments for patients with myocardial ischemia in the absence of angiographic obstructive coronary artery disease are limited. In these patients, particularly those with diabetes mellitus, diffuse coronary atherosclerosis and microvascular dysfunction is a common phenotype and may be accompanied by diastolic dysfunction. Our primary aim was to determine whether ranolazine would quantitatively improve exercise-stimulated myocardial blood flow and cardiac function in symptomatic diabetic patients without obstructive coronary artery disease...
May 4, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28471812/comparisons-of-noninvasive-methods-used-to-assess-exercise-stroke-volume-in-hfpef
#15
Erik H Van Iterson, Thomas P Olson, Barry A Borlaug, Bruce D Johnson, Eric M Snyder
INTRODUCTION: Cardiopulmonary exercise testing (CPET) plays an important role in properly phenotyping signs and symptoms of heart failure with preserved ejection fraction (HFpEF). The prognostic value of CPET is strengthened when accompanied by cardiac hemodynamic measurements. Although recognized as the 'Gold' standard, cardiac catheterization is impractical for routine CPET. Thus, advancing the scientific/methodologic understanding of noninvasive techniques for exercise cardiac hemodynamic assessment is clinically impactful in HFpEF...
May 4, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28465992/stress-induced-worsening-of-left-ventricular-diastolic-function-as-a-marker-of-myocardial-ischemia
#16
Mohamad Jihad Mansour, Wael Aljaroudi, Ali Mroueh, Omar Hamoui, Walid Honeine, Nada Khoury, Jinane Abi Nassif, Elie Chammas
BACKGROUND: Echocardiography has been the subject of interest in diagnosing diastolic dysfunction and estimating left ventricular filling pressures (LVFPs). The present study is set to estimate the correlation between the worsening of diastolic parameters and the evidence of inducible ischemia during an exercise stress echocardiography (SE) in comparison with the results of coronary computed tomographic angiogram (CCTA). METHODS: A total of 191 consecutive patients from the executive screening program who underwent exercise SE followed by CCTA were evaluated...
April 2017: Journal of Cardiovascular Echography
https://www.readbyqxmd.com/read/28465976/addition-of-exercise-to-dipyridamole-stress-echocardiography-in-order-to-carry-on-the-ischemic-cascade-role-in-the-diagnosis-of-coronary-artery-disease-and-prognostic-value
#17
Piergiuseppe Piovesana, Pietro Offelli, Francesca D'Ambrosio, Fabio De Conti, Virginia Scarabeo, Marco Panfili, Francesco Antonini-Canterin
BACKGROUND: Sensitivity of dipyridamole stress echocardiography (SE) is often lower than required. The aim of the present work is the evaluation of the association of dipyridamole and exercise echocardiography. METHODS: From June 2007 to January 2011, 259 consecutive patients referred to Camposampiero Echocardiography Laboratory underwent SE. Stress protocol started with dipyridamole infusion of 0.84 mg/kg over 6 min. In patients without a new dyssynergy after dipyridamole, SE was carried on with supine exercise...
October 2016: Journal of Cardiovascular Echography
https://www.readbyqxmd.com/read/28461150/angina-and-ischemia-at-2-years-with-bioresorbable-vascular-scaffolds-and-metallic-drug-eluting-stents-estrofa-ischemia-bvs-mdes-study
#18
José M de la Torre Hernández, José R Rumoroso, Soledad Ojeda, Salvatore Brugaletta, José D Cascón, Cristina Ruisánchez, Joaquín Sánchez Gila, Jessica Roa, Helena Tizón, Hipólito Gutiérrez, Mariano Larman, Tamara García Camarero, Eduardo Pinar, José F Díaz, Manuel Pan, Miren Morillas Bueno, José M Oyonarte, Luis Ruiz Guerrero, Mireia Ble, Ramón Rubio Patón, Román Arnold, Kattalin Echegaray, Gonzalo de la Morena, Manel Sabate
INTRODUCTION AND OBJECTIVES: Bioresorbable vascular scaffolds (BVS) have the potential to restore vasomotion but the clinical implications are unknown. We sought to evaluate angina and ischemia in the long-term in patients treated with BVS and metallic drug-eluting stents (mDES). METHODS: Multicenter study including patients with 24 ± 6 months of uneventful follow-up, in which stress echocardiography was performed and functional status was assessed by the Seattle Angina Questionnaire (SAQ)...
April 28, 2017: Revista Española de Cardiología
https://www.readbyqxmd.com/read/28455405/respiration-driven-excessive-sinus-tachycardia-treated-with-clonidine
#19
Matthew Emile Li Kam Wa, Patricia Taraborrelli, Sajad Hayat, Phang Boon Lim
A 26-year-old man presented to our syncope service with debilitating daily palpitations, shortness of breath, presyncope and syncope following a severe viral respiratory illness 4 years previously. Mobitz type II block had previously been identified, leading to a permanent pacemaker and no further episodes of frank syncope. Transthoracic echocardiography, electophysiological study and repeated urine metanepherines were normal. His palpitations and presyncope were reproducible on deep inspiration, coughing, isometric hand exercise and passive leg raises...
April 28, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28454836/right-ventricular-dysfunction-in-tetralogy-of-fallot-inhibition-of-the-renin-angiotensin-aldosterone-system-redefine-trial-rationale-and-design-of-a-randomized-double-blind-placebo-controlled-clinical-trial
#20
Jouke P Bokma, Michiel M Winter, Esmée M Kornaat, Hubert W Vliegen, Arie P van Dijk, Joost P van Melle, Folkert J Meijboom, Martijn C Post, Jacqueline K Berbee, Aeilko H Zwinderman, Barbara J M Mulder, Berto J Bouma
Renin-angiotensin-aldosterone system (RAAS) inhibition with angiotensin II receptor blockers or angiotensin-converting enzyme inhibitors is beneficial in patients with acquired left ventricular dysfunction. Adult patients with tetralogy of Fallot (TOF) with right ventricular (RV) dysfunction are at high risk for heart failure, arrhythmias, and sudden cardiac death. However, the efficacy of RAAS inhibition has not been established in these patients. METHODS: The REDEFINE is an investigator-initiated, multicenter, prospective, randomized, double-blind, placebo-controlled trial to study the effects of the angiotensin II receptor blocker losartan (target dosage of 150 mg once daily) in adult patients with TOF...
April 2017: American Heart Journal
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