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https://www.readbyqxmd.com/read/29471601/-bladder-rupture-during-intravesical-bcg-therapy-a-case-report
#1
Yusuke Iemura, Shinji Fukui, Yoshiaki Matsumura, Yoriaki Kagebayashi, Yuta Toyoshima, Takeshi Inoue, Shoji Samma
A 69-year-old man received transurethral resection (TUR) ofbladder tumor. The histopathological diagnosis was urothelial carcinoma, high grade, pT1+pTis. The surgical specimens obtained by second TUR showed no residual malignancy histopathologically. Intravesical Bacillus Calmette-Guerin (BCG) instillation therapy was initiated 2 months after the second TUR. He complained of lower abdominal pain and painful urination on the day following the second instillation of BCG. Computed tomography and cystography demonstrated rupture ofthe urinary bladder...
January 2018: Hinyokika Kiyo. Acta Urologica Japonica
https://www.readbyqxmd.com/read/29471598/-ureteral-cancer-developing-in-retrocaval-ureter-a-case-report
#2
Yoshiaki Matsumura, Yusuke Iemura, Shinji Fukui, Yoriaki Kagebayashi, Shoji Samma, Shigehiro Tsujimoto, Takashi Okada, Toru Kanno
Ureteral cancer in the retrocaval ureter is rare. We herein report a patient with this condition laparoscopically treated. A 69-year-old man was referred to us because of right ureteral cancer diagnosed during ureteroscopic surgery for a ureteral calculus. Histological diagnosis of the ureteroscopically biopsied material was non-invasive papillary urothelial carcinoma, low grade (G2). Computed tomography (CT) demonstrated a retrocaval ureter : a double J stent placed during ureteroscopy assisted the diagnosis...
January 2018: Hinyokika Kiyo. Acta Urologica Japonica
https://www.readbyqxmd.com/read/29471575/-breast-cancer-diagnostics-and-therapy-the-most-important-facts-for-internists
#3
Ulrich Hamann, Christine Ankel
LEARNING OBJECTIVES:  After reviewing this article, the participant should be able to: 1. Understand the epidemiology of breast cancer, its incidence and impact. 2. Appreciate the importance of early diagnosis and treatment. 3. Understand the concept of comprehensive breast cancer management and its multidisciplinarity. 4. Be knowledgeable about the entire process required to manage breast cancer, since the early diagnosis until the management of non breast related conditions derived from the treatment...
February 2018: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/29471560/knochensarkome
#4
Jendrik Hardes, Georg Gosheger, Timo Budny
Bone sarcomas are extremely rare representing approximately 0.2% among all cancer types. Due to the rarity of these tumors both the patients and the physicians can overlook or misinterpret the first often unspecific symptoms of these tumors (pain, limping and swelling). Therefore, radiographic examination (X-ray and/or MRI) of the involved region in case of inexplicable symptoms is strongly recommended. The most common primary malignant bone tumor entity is osteosarcoma, followed by chondrosarcoma and Ewing sarcoma...
February 2018: Zeitschrift Für Orthopädie und Unfallchirurgie
https://www.readbyqxmd.com/read/29471457/improving-anatomic-pathology-in-sub-saharan-africa-to-support-cancer-care
#5
Michael L Wilson, Stephanie Ayers, Daniel Berney, Alexia Eslan, Jeannette Guarner, Susan Lester, Ricard Masia, Zahir Moloo, Angela Mutuku, Drucilla Roberts, Jennifer Stall, Shahin Sayed
Objectives: Cancer care requires both accurate pathologic diagnosis as well as pathologic cancer staging. We evaluated three approaches to training pathologists in sub-Saharan Africa to perform pathologic cancer staging of breast, cervix, prostate, and colorectal cancers. Methods: One of three training methods was used at each workshop: didactic, case-based testing (CBT), or a blended approach. The project involved 52 participants from 16 pathology departments in 11 countries in East, Central, and Southern Africa...
February 19, 2018: American Journal of Clinical Pathology
https://www.readbyqxmd.com/read/29471407/plasma-copeptin-as-a-predictor-of-kidney-disease
#6
Sofia Enhörning, Anders Christensson, Olle Melander
Background: Plasma copeptin, a marker of vasopressin, is associated with renal function decline in the general population. Our aim was to study the links between elevated copeptin and future risk of kidney disease. Methods: Copeptin was measured in a sample of the Malmö Preventive Project (MPP) Reinvestigation (n = 5158) and in the Malmö Diet and Cancer Cardiovascular Cohort (MDC-CC) (n = 5162). According to national registers, 89 subjects in MPP and 180 in MDC-CC developed chronic kidney disease (CKD) during follow-up (8...
February 16, 2018: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/29470951/serum-level-of-long-noncoding-rna-h19-as-a-diagnostic-biomarker-of-multiple-myeloma
#7
Yafang Pan, Hongmei Chen, Xianjuan Shen, Xudong Wang, Shaoqing Ju, Meihong Lu, Hui Cong
Circulating long noncoding RNA (lncRNA) H19 has been reported to be a biomarker for cancer monitoring. The purpose of this study was to determine whether serum lncRNA could serve as a novel biomarker for the diagnosis of multiple myeloma (MM) and evaluate its value of clinical application. In our study, the expression of lncRNA H19 was up-regulated in 80 patients with MM and MM cell lines by RT-PCR analysis. Clinicopathological analysis showed the expression level of H19 could assist clinical staging, and the severity of the disease could be roughly determined according to the amount of H19 expressed in the patient serum...
February 19, 2018: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/29470859/added-value-of-second-biopsy-target-in-screen-detected-widespread-suspicious-breast-calcifications
#8
Nathalie M Falkner, Dana Hince, Gareth Porter, Ben Dessauvagie, Sanjay Jeganathan, Max Bulsara, Glen Lo
INTRODUCTION: There is controversy on the optimal work-up of screen-detected widespread breast calcifications: whether to biopsy a single target or multiple targets. This study evaluates agreement between multiple biopsy targets within the same screen-detected widespread (≥25 mm) breast calcification to determine if the second biopsy adds value. METHODS: Retrospective observational study of women screened in a statewide general population risk breast cancer mammographic screening program from 2009 to 2016...
February 22, 2018: Journal of Medical Imaging and Radiation Oncology
https://www.readbyqxmd.com/read/29470806/screening-of-over-1000-indian-patients-with-breast-and-or-ovarian-cancer-with-a-multi-gene-panel-prevalence-of-brca1-2-and-non-brca-mutations
#9
Jaya Singh, Nishita Thota, Suhasini Singh, Shila Padhi, Puja Mohan, Shivani Deshwal, Soumit Sur, Mithua Ghosh, Amit Agarwal, Ramesh Sarin, Rosina Ahmed, Sachin Almel, Basumita Chakraborti, Vinod Raina, Praveen K DadiReddy, B K Smruti, Senthil Rajappa, Chandragouda Dodagoudar, Shyam Aggarwal, Manish Singhal, Ashish Joshi, Rajeev Kumar, Ajai Kumar, Deepak K Mishra, Neeraj Arora, Aarati Karaba, Satish Sankaran, Shanmukh Katragadda, Arunabha Ghosh, Vamsi Veeramachaneni, Ramesh Hariharan, Ashraf U Mannan
PURPOSE: Breast and/or ovarian cancers are among the most common cancers in women across the world. In the Indian population, the healthcare burden of breast and/or ovarian cancers has been steadily rising, thus stressing the need for early detection, surveillance, and disease management measures. However, the burden attributable to inherited mutations is not well characterized. METHODS: We sequenced 1010 unrelated patients and families from across India with an indication of breast and/or ovarian cancers, using the TruSight Cancer panel which includes 14 genes, strongly associated with risk of hereditary breast and/or ovarian cancers...
February 22, 2018: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/29470704/relationship-between-sleep-and-exercise-as-colorectal-cancer-survivors-transition-off-treatment
#10
Theresa Coles, Antonia V Bennett, Xianming Tan, Claudio L Battaglini, Hanna K Sanoff, Ethan Basch, Roxanne E Jensen, Bryce B Reeve
PURPOSE: The primary objective of this study was to evaluate the relationship between exercise and sleep disturbance in a sample of individuals diagnosed with stage I, II, and III colorectal cancer (CRC) as patients transitioned off first-line treatment. We also sought to identify heterogeneity in the relationship between sleep disturbance and exercise. METHODS: Data were obtained from the MY-Health study, a community-based observational study of adults diagnosed with cancer...
February 22, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29470699/a-nested-case-control-study-on-the-risk-of-surgical-site-infection-after-thyroid-surgery
#11
F A Salem, M Almquist, E Nordenström, J Dahlberg, O Hessman, C I Lundgren, A Bergenfelz
INTRODUCTION: It is unclear if antibiotic prophylaxis reduces the risk of surgical site infection (SSI) in thyroid surgery. This study assessed risk factors for SSI and antibiotic prophylaxis in subgroups of patients. METHOD AND DESIGN: A nested case-control study on patients registered in the Swedish National Register for Endocrine Surgery was performed. Patients with SSI were matched 1:1 by age and gender to controls. Additional information on patients with SSI and controls was queried from attending surgeons using a questionnaire...
February 22, 2018: World Journal of Surgery
https://www.readbyqxmd.com/read/29470686/a-case-of-stage-ia-pancreatic-ductal-adenocarcinoma-accompanied-with-focal-pancreatitis-demonstrated-by-contrast-enhanced-ultrasonography
#12
Junko Fukuda, Sachiko Tanaka, Nobuko Ishida, Tatsuya Ioka, Kenji Ikezawa, Rena Takakura, Miho Nakao, Kazuyoshi Ohkawa, Kazuhiro Katayama, Shigenori Nagata
A patient with slight dilatation of the main pancreatic duct was followed-up with ultrasonography every 6 months as a high-risk case of pancreatic cancer. Twelve years later, a faint hypoechoic area 13 mm in diameter was first detected on the body of the pancreas. Contrast-enhanced ultrasonography revealed a well-demarcated hypoenhanced area 8 mm in diameter and a hyperenhanced area with an unclear margin. The former was suspected to be a small pancreatic cancer lesion, and the latter to be focal pancreatitis accompanying cancer...
February 22, 2018: Journal of Medical Ultrasonics
https://www.readbyqxmd.com/read/29470570/a-magnetic-resonance-imaging-based-prediction-model-for-prostate-biopsy-risk-stratification
#13
Sherif Mehralivand, Joanna H Shih, Soroush Rais-Bahrami, Aytekin Oto, Sandra Bednarova, Jeffrey W Nix, John V Thomas, Jennifer B Gordetsky, Sonia Gaur, Stephanie A Harmon, Mohummad Minhaj Siddiqui, Maria J Merino, Howard L Parnes, Bradford J Wood, Peter A Pinto, Peter L Choyke, Baris Turkbey
Importance: Multiparametric magnetic resonance imaging (MRI) in conjunction with MRI-transrectal ultrasound (TRUS) fusion-guided biopsies have improved the detection of prostate cancer. It is unclear whether MRI itself adds additional value to multivariable prediction models based on clinical parameters. Objective: To determine whether an MRI-based prediction model can reduce unnecessary biopsies in patients with suspected prostate cancer. Design, Setting, and Participants: Patients underwent MRI, MRI-TRUS fusion-guided biopsy, and 12-core systematic biopsy in 1 session...
February 22, 2018: JAMA Oncology
https://www.readbyqxmd.com/read/29470565/sociodemographic-medical-and-psychosocial-factors-associated-with-supportive-care-needs-in-adults-diagnosed-with-uveal-melanoma
#14
Timothy J Williamson, Alexandra Jorge-Miller, Tara A McCannel, Tammy M Beran, Annette L Stanton
Importance: Understanding supportive care needs in patients with cancer is important for developing approaches that enhance quality of life and promote satisfaction with care. Objective: To characterize the nature and frequency of sociodemographic, medical, and psychosocial factors associated with unmet needs in patients with uveal melanoma 1 week and 3 months after diagnosis. Design, Setting, and Participants: This 3-month, prospective, longitudinal survey study was conducted at a university-based ophthalmology practice from June 1, 2007, to July 1, 2011...
February 22, 2018: JAMA Ophthalmology
https://www.readbyqxmd.com/read/29470358/is-vulvovaginal-lichen-planus-associated-with-squamous-cell-carcinoma
#15
Tania Day, Geoff Otton, Ken Jaaback, Julie Weigner, James Scurry
OBJECTIVE: The aim of the study was to assess for the presence of vulvar lichen planus (LP) in association with human papillomavirus (HPV)-independent squamous cell carcinoma (SCC). MATERIALS AND METHODS: We performed a clinicohistopathologic review of consecutive vulvectomies and wide local excisions for HPV-independent vulvar or vaginal SCC from 2007 to 2017. Data collected included site of SCC, adjacent precursor lesions and dermatoses, dermatologic treatment, and outcome...
February 22, 2018: Journal of Lower Genital Tract Disease
https://www.readbyqxmd.com/read/29470104/association-between-utilization-of-chiropractic-services-for-treatment-of-low-back-pain-and-use-of-prescription-opioids
#16
James M Whedon, Andrew W J Toler, Justin M Goehl, Louis A Kazal
OBJECTIVE: Pain relief resulting from services delivered by doctors of chiropractic may allow patients to use lower or less frequent doses of opioids, leading to reduced risk of adverse effects. The objective of this investigation was to evaluate the association between utilization of chiropractic services and the use of prescription opioid medications. DESIGN: The authors used a retrospective cohort design to analyze health insurance claims data. SETTING: The data source was the all payer claims database administered by the State of New Hampshire...
February 22, 2018: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/29469780/non-dermatomal-varicella-zoster-skin-infection-disseminated-cutaneous-herpes-zoster-without-dermatome-in-an-immunosuppressed-woman
#17
Lindsay P Osborn, Philip R Cohen
Disseminated herpes zoster is defined as the presence of more than 20 lesions outside the dermatome. This unusual presentation is more common in immunosuppressed patients. Complications such as hepatitis, encephalitis, and pneumonitis are more likely in individuals with disseminated varicella zoster virus infection.A 63-year-old woman being treated for breast cancer developed multiple pustules and vesicles days after starting doxorubicin and cyclophosphamide chemotherapy. Ten individual lesions appeared on her chest, abdomen, back, and leg...
October 15, 2017: Dermatology Online Journal
https://www.readbyqxmd.com/read/29469762/anaplastic-large-cell-lymphoma-localized-to-the-left-breast-years-after-radiotherapy-for-breast-cancer
#18
Michelle S Min, Ali Al-Haseni, Farah Succaria, Lynne Goldberg, Adam Lerner, Debjani Sahni
Anaplastic large cell lymphoma (ALCL) is a rare type of non-Hodgkin lymphoma that can involve the skin primarily or secondarily. Our case describes an unusual presentation of eruptive tumors localized to the leftbreast region several years following breast cancer surgery and radiation for carcinoma of the breast. This report highlights the challenges in reachingthe diagnosis of an aggressive systemic lymphoma presenting on the skin.
January 15, 2018: Dermatology Online Journal
https://www.readbyqxmd.com/read/29469760/the-use-of-cyclosporine-for-stevens-johnson-syndrome-toxic-epidermal-necrolysis-spectrum-at-the-university-of-louisville-a-case-series-and-literature-review
#19
Clayton D Conner, Emily McKenzie, Cindy E Owen
INTRODUCTION: Cyclosporine therapy for Stevens-Johnson syndrome-toxic epidermal necrolysis (SJSTEN) was first reported in the literature by Renfro et al. in 1989. Herein we report an additional 4 cases of SJS-TEN treated with cyclosporine. METHODS: Case information was collected retroactively at the University of Louisville Hospital in Louisville, KY. All cases had a diagnosis of SJS or TEN by a dermatologist. All patients were ≥18 years of age and treated with cyclosporine during their admission...
January 1, 2018: Dermatology Online Journal
https://www.readbyqxmd.com/read/29469641/castrate-resistant-prostate-cancer-lessons-learnt-from-a-pilot-study-in-the-palliative-care-research-population
#20
Karyn A Sullivan, Ngaire Kingi, Phillip Good, Petra Vayne-Bossert, Janet R Hardy
BACKGROUND: Palliative care patients are inherently difficult to recruit to and retain on studies. Even when patients are recruited, it is hard to complete studies with sufficient data. There is a dearth of literature specific to men with castrate resistant prostate cancer (CRPC) and the clinical trials coordinator/research nurse's perspective in improving trial outcomes in palliative care. Objectives To describe the lessons learnt (by the nursing research team) from a prospective cohort study of men with CRPC and the practical implications for future research in this area...
February 2, 2018: International Journal of Palliative Nursing
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