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Eosinophilic fasciitis

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https://www.readbyqxmd.com/read/28440714/hypereosinophilic-syndrome-endomyocardial-biopsy-versus-echocardiography-to-diagnose-cardiac-involvement
#1
Joseph H Butterfield, Garvan C Kane, Catherine R Weiler
OBJECTIVE: To compare echocardiograms and endomyocardial biopsies to diagnose cardiac involvement in hypereosinophilic syndrome. METHODS: We examined the agreement between echocardiography and endomyocardial biopsies to detect cardiac involvement in hypereosinophilic syndrome by reviewing cases identified as hypereosinophilia or hypereosinophilic syndrome in Mayo Clinic databases from January 1978 through June 2009. Single-organ cases of eosinophilia such as eosinophilic fasciitis and eosinophilic gastroenteritis were excluded...
April 25, 2017: Postgraduate Medicine
https://www.readbyqxmd.com/read/28393380/th1-and-th17-polarized-immune-infiltrates-in-eosinophilic-fasciitis-a-potential-marker-for-histopathologic-distinction-from-morphea
#2
Andrea Primiani Moy, Elena Maryamchik, Olga V Nikolskaia, Rosalynn M Nazarian
Morphea (localized scleroderma) and eosinophilic fasciitis (EF) are rare fibrosing disorders which may present a diagnostic challenge. While histopathologic features are often distinct, in some cases there may be overlap. T-cells contribute to etiopathogenesis of both autoimmune conditions. We sought to determine whether T-cell immune polarization enables histopathologic distinction. We retrospectively examined clinicopathologically confirmed cases of morphea (n = 12) and EF (n = 8) using immunohistochemistry for CD3, CD8, and dual staining for CD4 with T-bet, GATA-3, STAT-3, or BNC-2 (transcription factors reported to be specific and mutually exclusive for Th1, Th2, Th17 and Th22 cells, respectively) to characterize the T-cell infiltrate...
April 10, 2017: Journal of Cutaneous Pathology
https://www.readbyqxmd.com/read/28379209/diagnostic-utility-of-magnetic-ressonance-imaging-in-eosinophilic-fasciitis
#3
Alexandra Daniel, Gisela Eugénio, Sara Serra, Armando Malcata, Maria João Salvador
No abstract text is available yet for this article.
April 5, 2017: Acta Reumatológica Portuguesa
https://www.readbyqxmd.com/read/28303481/morphea-and-eosinophilic-fasciitis-an-update
#4
REVIEW
Jorre S Mertens, Marieke M B Seyger, Rogier M Thurlings, Timothy R D J Radstake, Elke M G J de Jong
Morphea, also known as localized scleroderma, encompasses a group of idiopathic sclerotic skin diseases. The spectrum ranges from relatively mild phenotypes, which generally cause few problems besides local discomfort and visible disfigurement, to subtypes with severe complications such as joint contractures and limb length discrepancies. Eosinophilic fasciitis (EF, Shulman syndrome) is often regarded as belonging to the severe end of the morphea spectrum. The exact driving mechanisms behind morphea and EF pathogenesis remain to be elucidated...
March 16, 2017: American Journal of Clinical Dermatology
https://www.readbyqxmd.com/read/28300895/eosinophilic-fasciitis
#5
Elisa Baranski Lamback, Fernanda Simões Seabra Resende, Thiara Cristina Rocha Lenzi
Eosinophilic fasciitis is a rare sclerodermiform syndrome of unknown etiology. It is characterized by the thickening of the muscular fascia and subcutaneous tissue, with a variable infiltration of eosinophils. Peripheral eosinophilia, poly or monoclonal hypergammaglobulinemia and increased erythrocyte sedimentation rate can be seen. Clinical features begin acutely, with local edema and a painful and symmetrical stiffening of the limbs, progressing rapidly to fibrosis, which can limit joint movements. Some cases have a history of strenuous physical exercise or trauma...
September 2016: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/28277348/groove-sign-of-eosinophilic-fasciitis
#6
Renee Fruchter, Daniel R Mazori, Alisa N Femia
No abstract text is available yet for this article.
April 2017: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
https://www.readbyqxmd.com/read/28150344/a-case-of-eosinophilic-fasciitis-associated-with-pyoderma-gangrenosum
#7
LETTER
E L Maranda, R Sheinin, A Brys, B Rubin, H W Lim
No abstract text is available yet for this article.
February 1, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28112037/basidiobolomycosis-complicated-by-hydronephrosis-and-a-perinephric-abscess-presenting-as-a-hypertensive-emergency-in-a-7-year-old-boy
#8
Sriram Krishnamurthy, Rakesh Singh, Venkatesh Chandrasekaran, Gopinathan Mathiyazhagan, Meenachi Chidambaram, S Deepak Barathi, Subramanian Mahadevan
A 7-year-old boy presented with a chronic, indurated, tender left thigh swelling in association with a hypertensive emergency. He had a bilateral moderate degree of hydronephrosis and a left perinephric abscess, and MRI features of posterior reversible encephalopathy syndrome. Histopathological examination of the biopsy specimen demonstrated eosinophilic fasciitis with filamentous fungi. Basidiobolus ranarum was isolated from the culture. The fungus was also isolated from a perinephric fluid aspirate. Computerised tomography of the abdomen demonstrated features consistent with fungal invasion of the pelvic floor muscles and urinary bladder, leading to bilateral hydronephrosis...
January 23, 2017: Paediatrics and International Child Health
https://www.readbyqxmd.com/read/28009608/fosb-is-a-useful-diagnostic-marker-for-pseudomyogenic-hemangioendothelioma
#9
Yin P Hung, Christopher D M Fletcher, Jason L Hornick
Pseudomyogenic (epithelioid sarcoma-like) hemangioendothelioma is a distinctive vascular neoplasm of intermediate biological potential with a predilection for young adults and frequent multifocal presentation. Pseudomyogenic hemangioendothelioma is characterized by loose fascicles of plump spindled and epithelioid cells with abundant eosinophilic cytoplasm and coexpression of keratins and endothelial markers. Recently, a SERPINE1-FOSB fusion has been identified as a consistent genetic alteration in pseudomyogenic hemangioendothelioma...
May 2017: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/27875630/eosinophilic-fasciitis-with-subjacent-myositis
#10
Julia B Whitlock, Elliot L Dimberg, Duygu Selcen, Devon I Rubin
INTRODUCTION: Eosinophilic fasciitis (EF) is a rare disorder that can present with muscle symptoms that mimic other neuromuscular diseases. METHODS: We report the case of a 43-year-old woman with chronic muscle aches, tightness, and stiffness with hypertrophied, well-defined muscles despite physical inactivity, and thickened skin with reduced elasticity and discoloration. RESULTS: Except for mild peripheral eosinophilia, laboratory studies, including blood count, electrolytes, paraneoplastic panel, muscle enzymes, thyroid function, and serum protein electrophoresis, were normal...
November 22, 2016: Muscle & Nerve
https://www.readbyqxmd.com/read/27730034/a-rare-case-of-unilateral-eosinophilic-fasciitis-associated-with-ipsilateral-extragenital-lichen-sclerosus
#11
Aseem Sharma, Rahul Ray, Jandhyala Sridhar, Arti Trehan, Manish Khandare
Eosinophilic fasciitis, also known as Shulman's syndrome, is a fibrosing scleroderma-like syndrome, which is a distinct entity. A 55-year-old man, presented with progressive skin darkening, thickening, and tightening over the left lower limb since 6 months. Dermatological examination revealed a hyperpigmented indurated area on the left thigh, extending to the anterior aspect of the left leg. A well-defined hypopigmented indurated plaque was present over the left iliac region. Histopathology and imaging studies confirmed the diagnosis of eosinophilic fasciitis and lichen sclerosus...
September 2016: Indian Dermatology Online Journal
https://www.readbyqxmd.com/read/27543875/shulman-disease-eosinophilic-fasciitis-in-x-linked-agammaglobulinemia
#12
A Pituch-Noworolska, H Mach-Tomalska, A Szaflarska, D Adamek
X-linked agammaglobulinemia (XLA) diagnosed in the first year of life is an immunodeficiency with a life-long indication for substitution of immunoglobulins, due to lack of B lymphocytes in the periphery. The decrease of bacterial infection frequency and severity is an effect of immunoglobulin replacement. However, in the majority of patients bronchiectasis and chronic sinusitis with an overgrown mucous membrane develop despite regular substitution. Autoimmune diseases as co-existing diseases in XLA are noted in a few patients presenting symptoms associated with arthritis, scleroderma and myositis...
June 2016: Polish Journal of Pathology: Official Journal of the Polish Society of Pathologists
https://www.readbyqxmd.com/read/27541801/high-dose-intravenous-pulse-methotrexate-in-patients-with-eosinophilic-fasciitis
#13
Jorre S Mertens, Manon C Zweers, Wietske Kievit, Hanneke K A Knaapen, Martijn Gerritsen, Timothy R D J Radstake, Frank H J van den Hoogen, Marjonne C W Creemers, Elke M G J de Jong
Importance: Eosinophilic fasciitis (EF) is a connective tissue disorder in which conventional treatment leads to disappointing results in a proportion of patients. Therefore, we investigated high-dose intravenous (IV) pulse methotrexate (MTX) as a treatment for EF. Objective: To examine safety and effects of monthly high-dose IV pulse MTX in EF. Design, Setting, and Participants: For this prospective single-arm study, we recruited 12 patients diagnosed with biopsy specimen-proven EF between 2006 and 2009 from the Department of Dermatology and Rheumatology at the Radboud University Medical Centre...
November 1, 2016: JAMA Dermatology
https://www.readbyqxmd.com/read/27525080/successful-treatment-of-aplastic-anemia-paroxysmal-nocturnal-hemoglobinuria-associated-with-eosinophilic-fasciitis-with-matched-unrelated-donor-allogeneic-peripheral-blood-stem-cell-transplantation
#14
Koji Sasaki, Uday Popat, Preetesh Jain, Tapan Kadia, Krina Patel, Keyur Patel, Nitin Jain, Koichi Takahashi, Ken Young, Roberto N Miranda, Thein H Oo, Huifang Lu, Naveen Pemmaraju
We report the first patient case of successful treatment intervention for both eosinophilic fasciitis and aplastic anemia with allogeneic peripheral blood stem cell transplantation from a matched unrelated donor after multiple immunosuppressant failure.
August 2016: Clinical Case Reports
https://www.readbyqxmd.com/read/27523020/eosinophilic-fasciitis-illustrated-by-18-f-fdg-pet-ct
#15
Ryota Kurimoto, Kei Ikeda, Daiki Nakagomi, Hiroshi Nakajima
No abstract text is available yet for this article.
2016: Internal Medicine
https://www.readbyqxmd.com/read/27407276/eosinophilic-fasciitis-after-parasite-infection
#16
Marta Oliveira, Fabia Patinha, Antonio Marinho
Eosinophilic fasciitis is a systemic inflammatory disease characterized by symmetrical swelling and skin induration of the distal portions of the arms and/or legs, evolving into a scleroderma-like appearance, accompanied by peripheral blood eosinophilia. It is a rare disease with a poorly understood etiology. Corticosteroid treatment remains the standard therapy, either taken alone or in association with an immunosuppressive drug. This paper presents a case of a male patient with palpebral edema and marked eosinophilia, diagnosed with intestinal parasitic infection in October 2006...
2016: Reumatologia
https://www.readbyqxmd.com/read/27293946/development-of-eosinophilic-fasciitis-during-infliximab-therapy-for-psoriatic-arthritis
#17
Richard Hariman, Payal Patel, Jennifer Strouse, Michael P Collins, Ann Rosenthal
Eosinophilic fasciitis (EF) is a rare disorder involving chronic inflammation of the fascia and connective tissue surrounding muscles, nerves, and blood vessels. While its pathogenesis is not entirely understood, this disorder is thought to be autoimmune or allergic in nature. We present here a case of a 59-year-old male who developed peripheral eosinophilia and subsequent eosinophilic fasciitis during treatment with infliximab. To our knowledge, eosinophilic fasciitis has not been previously described in patients during treatment with an inhibitor of tumor necrosis factor α...
2016: Case Reports in Rheumatology
https://www.readbyqxmd.com/read/27268780/juvenile-eosinophilic-fasciitis-three-case-reports-with-review-of-the-literature
#18
Riccardo Papa, Paolo Nozza, Claudio Granata, Roberta Caorsi, Marco Gattorno, Alberto Martini, Paolo Picco
OBJECTIVES: Eosinophilic fasciitis is an uncommon scleroderma-like disorder characterised by induration and thickening of skin and soft tissue, usually associated with peripheral eosinophilia, poorly characterised in childhood. METHODS: We report 3 paediatric cases of eosinophilic fasciitis showing unusual clinical and histopathological features with a review of the literature. RESULTS: All cases presented progressive motility impairment started from upper limbs with no skin abnormalities...
May 2016: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/27136633/correspondence-the-association-between-morphea-profunda-and-monoclonal-gammopathy-a-case-series
#19
LETTER
Justin Endo, Nicole Strickland, Simer Grewal, Travis Vandergriff, Thomas Keenan, B Jack Longley, Heidi Jacobe
It is known that eosinophilic fasciitis can be associated with monoclonal gammopathy. There is clinical similarity between eosinophilic fasciitis and morphea profunda, but it is unclear whether morphea profunda might be associated with monoclonal gammopathy. The temporal quantification of gammopathy in morphea profunda has not been well characterized. We describe four patients with morphea profunda that were associated with monoclonal gammopathy. Three were associated with monoclonal IgG protein and one with IgM...
March 16, 2016: Dermatology Online Journal
https://www.readbyqxmd.com/read/27033137/a-case-of-refractory-eosinophilic-fasciitis-with-eosinophilic-vasculitis
#20
Shino Minami, Noriki Fujimoto, Toshifumi Takahashi, Takeshi Nakanishi, Toshihiro Tanaka
No abstract text is available yet for this article.
June 1, 2016: European Journal of Dermatology: EJD
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