Daniel Petroni, Philippe Bégin, J Andrew Bird, Terri Brown-Whitehorn, Hey J Chong, David M Fleischer, Rémi Gagnon, Stacie M Jones, Stephanie Leonard, Melanie M Makhija, Roxanne C Oriel, Wayne G Shreffler, Sayantani B Sindher, Gordon L Sussman, William H Yang, Katharine J Bee, Timothée Bois, Dianne E Campbell, Todd D Green, Karine Rutault, Hugh A Sampson, Robert A Wood
IMPORTANCE: No approved treatment exists for allergen-specific immunoglobulin E (IgE)-mediated cow's milk allergy (CMA), a common childhood food allergy. OBJECTIVE: To assess dose, efficacy, and safety of epicutaneous immunotherapy with Viaskin milk in children with IgE-mediated CMA. DESIGN, SETTING, AND PARTICIPANTS: A phase 1/2, 2-part, randomized, double-blind, placebo-controlled dose-ranging clinical trial in children aged 2 to 17 years with IgE-mediated CMA was conducted between November 2014 through December 2017...
February 26, 2024: JAMA Pediatrics