keyword
https://read.qxmd.com/read/38461568/survival-associated-with-the-use-of-one-step-nucleic-acid-amplification-osna-to-detect-sentinel-lymph-node-metastasis-in-cervical-cancer
#21
JOURNAL ARTICLE
Nicolò Bizzarri, Camilla Fedele, Elena Teodorico, Camilla Certelli, Luigi Pedone Anchora, Vittoria Carbone, Diana Giannarelli, Anna Fagotti, Gian Franco Zannoni, Michele Valente, Denis Querleu, Gabriella Ferrandina, Giovanni Scambia, Francesco Fanfani
INTRODUCTION: Sentinel lymph node (SLN) biopsy is part of surgical treatment of apparent early-stage cervical cancer. SLN is routinely analyzed by ultrastaging and immunohistochemistry. The aim of this study was to assess the survival of patients undergoing SLN analyzed by one-step nucleic acid amplification (OSNA) compared with ultrastaging. METHODS: Single-center, retrospective, cohort study. Patients undergoing primary surgery and SLN mapping ( ±pelvic lymphadenectomy) for apparent early-stage cervical cancer between May 2017 and January 2021 were included...
March 5, 2024: European Journal of Surgical Oncology
https://read.qxmd.com/read/38460739/how-do-spino-pelvic-characteristics-change-post-total-hip-arthroplasty-a-longitudinal-assessment-raising-awareness-of-the-postoperative-period
#22
JOURNAL ARTICLE
Aidin Eslam Pour, Moritz Innmann, Franz Reichel, Bibiane Schaper, Tobias Renkawitz, Christian Merle, George Grammatopoulos
INTRODUCTION: Spino-pelvic characteristics, including sacral slope (SS), are commonly evaluated in different positions pre-THA (total hip arthroplasty). This study aimed to: 1) investigate the change in spino-pelvic parameters at 7 days (early) and 1 year post-THA; and 2) identify patient characteristics associated with a change in SS of more than 7° post-THA. METHODS: We prospectively studied 250 patients who underwent unilateral THA [132 women, age 66 years (range, 32 to 88)] and underwent biplanar images preoperatively and at 7 days and 1 year post-THA...
March 7, 2024: Journal of Arthroplasty
https://read.qxmd.com/read/38459580/protocol-of-a-phase-ii-study-to-evaluate-the-efficacy-and-safety-of-deep-inspiration-breath-hold-daily-online-adaptive-radiotherapy-for-centrally-located-lung-tumours-pudding-study
#23
JOURNAL ARTICLE
Noriko Kishi, Masahiro Yoneyama, Hiroyuki Inoo, Minoru Inoue, Hiraku Iramina, Akiyoshi Nakakura, Tomohiro Ono, Hideaki Hirashima, Takanori Adachi, Norimasa Matsushita, Makoto Sasaki, Takahiro Fujimoto, Mitsuhiro Nakamura, Yukinori Matsuo, Takashi Mizowaki
BACKGROUND: Centrally located lung tumours present a challenge because of their tendency to exhibit symptoms such as airway obstruction, atelectasis, and bleeding. Surgical resection of these tumours often requires sacrificing the lungs, making definitive radiotherapy the preferred alternative to avoid pneumonectomy. However, the proximity of these tumours to mediastinal organs at risk increases the potential for severe adverse events. To mitigate this risk, we propose a dual-method approach: deep inspiration breath-hold (DIBH) radiotherapy combined with adaptive radiotherapy...
March 8, 2024: Radiation Oncology
https://read.qxmd.com/read/38457811/stronger-association-of-objective-physical-metrics-with-baseline-patient-reported-outcome-measures-than-preoperative-standing-sagittal-parameters-for-adult-spinal-deformity-patients
#24
JOURNAL ARTICLE
Tej D Azad, Frank J Schwab, Virginie Lafage, Alex Soroceanu, Robert K Eastlack, Renaud Lafage, Khaled M Kebaish, Robert A Hart, Bassel Diebo, Michael P Kelly, Justin S Smith, Alan H Daniels, D Kojo Hamilton, Munish Gupta, Eric O Klineberg, Themistocles S Protopsaltis, Peter G Passias, Shay Bess, Jeffrey L Gum, Richard Hostin, Stephen J Lewis, Christopher I Shaffrey, Douglas Burton, Lawrence G Lenke, Christopher P Ames, Justin K Scheer
OBJECTIVE: Sagittal alignment measured on standing radiography remains a fundamental component of surgical planning for adult spinal deformity (ASD). However, the relationship between classic sagittal alignment parameters and objective metrics, such as walking time (WT) and grip strength (GS), remains unknown. The objective of this work was to determine if ASD patients with worse baseline sagittal malalignment have worse objective physical metrics and if those metrics have a stronger relationship to patient-reported outcome metrics (PROMs) than standing alignment...
March 8, 2024: Journal of Neurosurgery. Spine
https://read.qxmd.com/read/38454820/2023-korean-sexually-transmitted-infections-guidelines-for-non-gonococcal-bacterial-infection-chlamydia-syphilis-etc-by-the-korean-association-of-urogenital-tract-infection-and-inflammation
#25
REVIEW
Joongwon Choi, Jin Bong Choi, Sangrak Bae, Chan Ho Lee, Yu Seob Shin, Dalsan You, Joo Yong Lee, Seung-Ju Lee, Kyu Won Lee
Non-gonococcal sexually transmitted infections (STIs) include chlamydia, syphilis, and chancroids. Chlamydia is the most common STI caused by Chlamydia trachomatis and is mainly transmitted through sexual intercourse or vertical transmission at birth. Although symptoms are mostly absent or mild, untreated chlamydial infections in females can lead to pelvic inflammatory disease, chronic pelvic pain, and infertility due to the narrowing of fallopian tubes. Syphilis is caused by Treponema pallidum and is divided into phase I, phase II, latent syphilis, and phase III...
March 2024: Investigative and Clinical Urology
https://read.qxmd.com/read/38454629/acetabular-fleck-sign-outcomes-of-surgical-repair
#26
JOURNAL ARTICLE
Stephanie Chen, Kirsten Tulchin-Francis, Dan Gaines, Allen Kadado, Craig Smith, Kevin Klingele
BACKGROUND: Traumatic, posterior hip dislocations in the pediatric population are typically managed by closed reduction to achieve a concentric hip joint. The presence of an acetabular "fleck" sign, despite concentric reduction, has been shown to signify significant hip pathology. The purpose of this study was to evaluate the outcomes of open labral repair through a surgical hip dislocation (SHD) in a consecutive series of patients with an acetabular "fleck" sign associated with a traumatic hip dislocation/subluxation...
March 8, 2024: Journal of Pediatric Orthopedics
https://read.qxmd.com/read/38449997/short-term-outcomes-of-first-100-laparoscopic-colorectal-surgeries-at-a-newly-developed-surgical-setup-at-peshawar
#27
JOURNAL ARTICLE
Muhammad F Shah, Irfan Ul Islam Nasir, Riaz Ahmad, Sajjad Ahmad, Aalia Amjad, Khush Bakht Zaineb, Romana Rehman
BACKGROUND: The incidence of colorectal cancer (CRC) has risen steadily, necessitating innovative strategies for diagnosis and treatment. Minimally invasive surgery, exemplified by laparoscopic techniques, has emerged as a transformative approach in colorectal surgical practices. Laparoscopy offers advantages such as improved aesthetic outcomes, reduced post-operative pain, early patient mobilization, and shorter hospital stays. OBJECTIVE: This study aims to present the short-term surgical outcomes of the first 100 elective laparoscopic CRC resections performed at a newly established tertiary care cancer center in Peshawar, Pakistan...
February 2024: Curēus
https://read.qxmd.com/read/38447561/-sagittal-profi-le-of-the-spine-in-patients-after-lumbar-stabilisation-surgeries
#28
JOURNAL ARTICLE
J Pešek, M Repko, L Ryba, D Matejička
PURPOSE OF THE STUDY: Spine stabilization surgery is nowadays one of the most common spinal surgical procedures. Spinopelvic alignment is considered to be an important factor impacting the patients' preoperative diffi culties as well as the outcome of surgery. In our study, the outcomes of stabilization surgeries in patients with lumbar spine disorders were evaluated - especially in those with stenosis and spondylolisthesis, in whom the importance of sagittal parameters were assessed with respect to the patients' clinical outcomes and diffi culties...
2024: Acta Chirurgiae Orthopaedicae et Traumatologiae Cechoslovaca
https://read.qxmd.com/read/38438176/gynecological-sarcomas-surgical-management-primary-metastatic-and-recurrent-disease
#29
REVIEW
Gwenael Ferron, Guillaume Bataillon, Alejandra Martinez, Frederic Chibon, Thibaud Valentin
Adult-type gynecological soft tissue and visceral sarcomas are rare tumors, with an estimated incidence of 13% of all sarcomas and 4% of all gynecological malignancies. They most often develop in the uterus (83%), followed by the ovaries (8%), vulva and vagina (5%), and other gynecological organs (2%). The objective of this review is to provide an overview of the current management of gynecological sarcomas, according to international guidelines. The management of gynecological sarcomas should follow the recommendations for the management of soft tissue and visceral sarcomas...
March 4, 2024: International Journal of Gynecological Cancer
https://read.qxmd.com/read/38438109/fragility-fractures-of-the-pelvis-first-48-cases-of-surgical-treatment-at-a-level-1-trauma-center-in-france
#30
JOURNAL ARTICLE
Luca Tolosano, Clementine Rieussec, Bérengère Sauzeat, Gauthier Caillard, Sabine Drevet, Gael Kerschbaumer, Geoffrey Porcheron, Daniel Wagner, Pol Maria Rommens, Jérôme Tonetti, Mehdi Boudissa
INTRODUCTION: Longer life expectancy is accompanied by a higher incidence of fragility fractures of the pelvis (FFP), which has repercussions on mortality and nursing home admissions. Given the paucity of data at French healthcare facilities, we carried out a retrospective study to 1) evaluate how surgical treatment of FFP with posterior displacement (type III and IV according to Rommens and Hofmann) affects a patient's pain, functional status and ability to stay at home and 2) evaluate the postoperative complications and mortality rate...
March 2, 2024: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://read.qxmd.com/read/38436874/a-case-of-seronegative-microscopic-polyangiitis-following-the-diagnosis-of-renal-pelvic-carcinoma
#31
JOURNAL ARTICLE
Narumichi Iwamura, Kanako Tsutsumi, Yuki Ueno, Yasuhisa Tamura, Toshiaki Nakano
The incidence rate of malignancy in patients with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is higher than that in the general population. Malignancy has been indicated to be a risk factor or inducer of AAV. Herein, we report the case of a healthy 84-year-old man with seronegative microscopic polyangiitis (MPA) after the diagnosis of renal pelvic carcinoma. Four weeks before admission, his estimated glomerular filtration rate (eGFR) was 85 ml/min/1.73 m2 , and no hematuria or proteinuria was detected...
March 4, 2024: CEN Case Reports
https://read.qxmd.com/read/38427287/secondary-analysis-of-late-major-gastrointestinal-and-genitourinary-toxicities-in-unfavorable-risk-prostate-cancer-patients-receiving-docetaxel-insights-from-a-randomized-trial
#32
JOURNAL ARTICLE
Tyler Walburn, Ming-Hui Chen, Marian Loffredo, Elizabeth McMahon, Peter F Orio, Paul L Nguyen, Anthony V D'Amico, Mutlay Sayan
BACKGROUND: This study sought to evaluate the late toxicity associated with neoadjuvant and concurrent docetaxel and radiation therapy in patients with prostate cancer. METHODS: A secondary analysis was performed of the phase 3 multicenter randomized trial (Dana-Farber Cancer Institute 05-043) including 350 patients with nonmetastatic unfavorable-risk prostate cancer. Patients were randomized 1:1 to receive androgen deprivation therapy, radiation therapy, and docetaxel versus androgen deprivation therapy and radiation therapy...
March 1, 2024: Cancer
https://read.qxmd.com/read/38427055/history-of-pain-around-the-lumbopelvic-region-during-perinatal-period-a-prospective-cohort-study
#33
JOURNAL ARTICLE
Saori Morino, Mika Ishihara, Fumiko Umezaki, Hiroko Hatanaka, Mamoru Yamashita, Tomoki Aoyama
PURPOSE: Many women experience pain around the low back and pelvic girdle during/after pregnancy. These pains have different risk factors and require independent management strategies. Therefore, an epidemiological database is required to understand when each type of pain occurs, and how serious it could be. Thus, the history of pain in the lumbopelvic region throughout the perinatal period was investigated. METHODS: The information of 170 women recruited at the obstetrics and gynecology clinics in Japan was collected at 12, 24, 30, and 36 weeks of pregnancy, in the early days after childbirth, and one month after childbirth...
March 1, 2024: European Spine Journal
https://read.qxmd.com/read/38425064/-effect-of-k%C3%A3-mmell-s-disease-with-kyphosis-on-spinal-pelvic-sagittal-parameters
#34
JOURNAL ARTICLE
Shou-Yu He, Ji-Kang Min, Hai-Dong Li, Qiang-Hua Zhang, Ji-Lin Dai
OBJECTIVE: To explore the effect of Kümmell's disease with kyphosis on the sagittal morphology of the spine-pelvis. METHODS: A retrospective analysis of 34 patients of Kümmell's disease with kyphosis (Kümmell group) admitted from August 2015 to September 2022, including 10 males and 24 females with an average age of (71.1±8.5) years old. A control group of 37 asymptomatic population aged (69.3±6.7) years old was matched...
February 25, 2024: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://read.qxmd.com/read/38423758/sacroiliac-radiographic-progression-over-10-years-in-axspa-data-from-the-desir-inception-cohort
#35
JOURNAL ARTICLE
Anna Molto, Clementina López-Medina, Alexandre Sepriano, Sofia Ramiro, Manouk de Hooge, Miranda van Lunteren, Victoria Navarro-Compán, Daniel Wendling, Maxime Dougados
OBJECTIVES: To evaluate sacroiliac radiographic progression over a 10-year follow-up and determine the baseline factors associated with such progression in patients with recent-onset axial spondyloarthritis (axSpA, <3 years). METHODS: This analysis was performed in the DESIR cohort (NCT01648907). The radiographic status of the patients (radiographic axSpA (r-axSpA) vs non-radiographic axSpA (nr-axSpA)) was based on the modified New York (mNY) criteria...
February 29, 2024: Annals of the Rheumatic Diseases
https://read.qxmd.com/read/38420224/triangular-osteosynthesis-as-a-surgical-treatment-option-for-unstable-sacral-fracture-fixation-with-sacroiliac-dislocation-a-case-report
#36
Anurag Baghel, Mohit Kumar Verma, Sanjay Sharma
INTRODUCTION: Sacral fractures, which can occur in young individuals following road traffic accidents or falls from a height, as well as in elderly individuals with osteoporosis after minor trauma, are considered a diverse type of fracture. The incidence of non-osteoporotic sacral fractures is estimated to be 2.1/100,000 people, whereas osteoporotic fractures are estimated to affect 1-5% of elderly individuals at risk. Triangular osteosynthesis is a relatively new fixation technique used as a surgical treatment for unstable sacral fractures...
February 2024: Journal of Orthopaedic Case Reports
https://read.qxmd.com/read/38420051/computed-tomography-findings-in-a-case-of-uterine-rupture-as-a-complication-of-pyometra
#37
Fadhila Mohd Hanapiah, Zul Khairul Azwadi Ismail, Othman Puteh, Mohd Ezane Aziz
Uterine rupture in the setting of pyometra is a rare occasion, with an incidence of less than 0.5%. The clinical manifestation of a perforated pyometra is non-specific; therefore, it can mimic many other causes of acute abdomen, such as perforated viscus, acute appendicitis, or diverticulitis, which poses unique challenges to diagnosis solely based on clinical information. We reviewed a case of an elderly postmenopausal lady who presented with a sudden onset of generalized abdominal pain, preceded by fever and vomiting...
January 2024: Curēus
https://read.qxmd.com/read/38418867/hard-flaccid-syndrome-symptoms-comorbidities-and-self-reported-efficacy-and-satisfaction-of-treatments-a-cross-sectional-survey
#38
JOURNAL ARTICLE
Jenny Niedenfuehr, David M Stevens
Hard flaccid syndrome (HFS) is a poorly understood condition with no formal consensus on its definition. We aimed to advance the understanding of HFS by evaluating symptom prevalence, cause of symptom onset, comorbidities, and self-reported efficacy and satisfaction with current treatments. An online, open, 42-question survey on Qualtrics with purposive and convenience sampling methods was conducted between May 9 and June 9, 2023 on participants self-identifying as having HFS. Participants were recruited through social media platforms...
February 28, 2024: International Journal of Impotence Research
https://read.qxmd.com/read/38418758/efficacy-and-safety-of-transvaginal-mesh-repair-in-a-cohort-with-a-minimum-of-10-year-follow-up
#39
JOURNAL ARTICLE
Zhibo Zhang, Jianbin Guo, Weijie Tian, Ye Zhang, Yuelun Zhang, Tianshu Sun, Jiali Duan, Xinmiao Bao, Yuan Wang, Yang Ye, Qianqian Gao, Honghui Shi, Abraham Nick Morse, Juan Chen, Lan Zhu
Although transvaginal mesh (TVM) repair is no longer used in some countries, long-term outcomes after TVM surgery are of great importance globally. However, reports with follow-up >10 years are limited. Thus, this study aimed to report outcomes in a prospective cohort with at least 10 years of follow-up. Women with stage III-IV symptomatic prolapse were approached consecutively from 2008 to 2013 at one tertiary hospital. The main outcome measure was symptomatic failure. Secondary outcomes included anatomic failure, recurrence, patient satisfaction, complications, and reoperation...
February 26, 2024: Science China. Life Sciences
https://read.qxmd.com/read/38417069/characteristics-of-spinal-morphology-according-to-the-current-and-theoretical-roussouly-classification-systems-in-a-diverse-asymptomatic-cohort-multi-ethnic-alignment-normative-study-means
#40
JOURNAL ARTICLE
Yong Shen, Zeeshan M Sardar, Matan Malka, Prerana Katiyar, Gabriella Greisberg, Fthimnir Hassan, Justin L Reyes, Jean-Charles Le Huec, Stephane Bourret, Kazuhiro Hasegawa, Hee Kit Wong, Gabriel Liu, Hwee Weng Dennis Hey, Hend Riahi, Michael Kelly, Joseph M Lombardi, Lawrence G Lenke
STUDY DESIGN: Cross-sectional cohort study. OBJECTIVE: To classify spinal morphology using the "current" and "theoretical" Roussouly systems and assess sagittal alignment in an asymptomatic cohort. METHODS: 467 asymptomatic volunteers were recruited from 5 countries. Radiographic parameters were measured via the EOS imaging system. "Current" and "theoretical" Roussouly classification was assigned with sagittal whole spine imaging using sacral slope (SS), pelvic incidence (PI), and the lumbar apex...
February 28, 2024: Global Spine Journal
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