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https://www.readbyqxmd.com/read/29139105/preoperative-medical-therapy-before-surgery-for-uterine-fibroids
#1
REVIEW
Anne Lethaby, Lucian Puscasiu, Beverley Vollenhoven
BACKGROUND: Uterine fibroids occur in up to 40% of women aged over 35 years. Some are asymptomatic, but up to 50% cause symptoms that warrant therapy. Symptoms include anaemia caused by heavy menstrual bleeding, pelvic pain, dysmenorrhoea, infertility and low quality of life. Surgery is the first choice of treatment. In recent years, medical therapies have been used before surgery to improve intraoperative and postoperative outcomes. However, such therapies tend to be expensive.Fibroid growth is stimulated by oestrogen...
November 15, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29138912/long-term-follow-up-after-non-operative-management-of-blunt-splenic-and-liver-injuries-a-questionnaire-based-survey
#2
Peter Moreno, Matthias Von Allmen, Tobias Haltmeier, Daniel Candinas, Beat Schnüriger
BACKGROUND: Non-operative management (NOM) of blunt splenic or liver injuries (solid organ injury, SOI) has become the standard of care in hemodynamically stable patients. However, the incidence of long-term symptoms in these patients is currently not known. The aim of this study was to assess long-term symptoms in patients undergoing successful NOM (sNOM) for SOI. METHODS: Long-term posttraumatic outcomes including chronic abdominal pain, irregular bowel movements, and recurrent infections were assessed using a specifically designed questionnaire and analyzed by univariable analysis...
November 14, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/29136127/risk-of-pelvic-inflammatory-disease-in-relation-to-chlamydia-and-gonorrhea-testing-repeat-testing-and-positivity-a-population-based-cohort-study
#3
Joanne Reekie, Basil Donovan, Rebecca Guy, Jane S Hocking, John M Kaldor, Donna B Mak, Sallie Pearson, David Preen, Louise Stewart, James Ward, Bette Liu
Background: There is uncertainty around whether the risks of pelvic inflammatory disease (PID) differ following Chlamydia trachomatis (chlamydia) and Neisseria gonorrhoeae (gonorrhea) infection. We quantified the risk of PID associated with chlamydia and gonorrhea infection and subsequent repeat infections in a whole-population cohort. Methods: A cohort of 315123 Western Australian women, born during 1974-1995, was probabilistically linked to chlamydia and gonorrhea testing records and to hospitalizations and emergency department presentations for PID from 2002 to 2013...
November 9, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29132441/early-screening-for-chlamydia-trachomatis-in-young-women-for-primary-prevention-of-pelvic-inflammatory-disease-i-predict-study-protocol-for-a-randomised-controlled-trial
#4
Jeanne Tamarelle, Anne C M Thiébaut, Bénédicte Sabin, Cécile Bébéar, Philippe Judlin, Arnaud Fauconnier, Delphine Rahib, Layidé Méaude-Roufai, Jacques Ravel, Servaas A Morré, Bertille de Barbeyrac, Elisabeth Delarocque-Astagneau
BACKGROUND: Genital infection with Chlamydia trachomatis (Ct) is the most common bacterial sexually transmitted infection, especially among young women. Mostly asymptomatic, it can lead, if untreated, to pelvic inflammatory disease (PID), tubal factor infertility and ectopic pregnancy. Recent data suggest that Ct infections are not controlled in France and in Europe. The effectiveness of a systematic strategy for Ct screening in under-25 women remains controversial. The main objective of the i-Predict trial (Prevention of Diseases Induced by Chlamydia trachomatis) is to determine whether early screening and treatment of 18- to-24-year-old women for genital Ct infection reduces the incidence of PID over 24 months...
November 13, 2017: Trials
https://www.readbyqxmd.com/read/29130653/-advances-in-diagnosis-and-treatment-of-posterior-distal-injury-of-pelvic-fracture
#5
REVIEW
Zhen Tan, Guang-Lin Wang
Pelvic fracture is one of the common diseases of traumatic orthopedics. With the increase of accidents such as traffic accidents,high craters and crush injuries in China,the incidence of pelvic fractures is also increasing year by year. Since pelvic bones and the ligament structure are close to neurovascular,cavity organs and the urogenital structure,early diagnosis and treatment of pelvic fractures is essential for preventing early complications and late sequelae. The treatment of pelvic ring injury has been the focus of pelvic fracture treatment,which determines the outcome of treatment...
September 2017: Sichuan da Xue Xue Bao. Yi Xue Ban, Journal of Sichuan University. Medical Science Edition
https://www.readbyqxmd.com/read/29128208/multi-institutional-evaluation-of-elective-nodal-irradiation-and-or-androgen-deprivation-therapy-with-postprostatectomy-salvage-radiotherapy-for-prostate-cancer
#6
Stephen J Ramey, Shree Agrawal, Matthew C Abramowitz, Drew Moghanaki, Thomas M Pisansky, Jason A Efstathiou, Jeff M Michalski, Daniel E Spratt, Jason W D Hearn, Bridget F Koontz, Stanley L Liauw, Alan Pollack, Mitchell S Anscher, Robert B Den, Kevin L Stephans, Anthony L Zietman, W Robert Lee, Andrew J Stephenson, Rahul D Tendulkar
BACKGROUND: Outcomes with postprostatectomy salvage radiation therapy (SRT) are not ideal. Little evidence exists regarding potential benefits of adding whole pelvic radiation therapy (WPRT) alone or in combination with androgen deprivation therapy (ADT). OBJECTIVE: To explore whether WPRT and/or ADT added to prostate bed radiation therapy (PBRT) improves freedom from biochemical failure (FFBF) or distant metastases (DM). DESIGN, SETTING, AND PARTICIPANTS: A database was compiled from 10 academic institutions of patients with postprostatectomy prostate-specific antigen (PSA) >0...
November 8, 2017: European Urology
https://www.readbyqxmd.com/read/29127513/pentosidine-concentration-is-associated-with-degenerative-lumbar-scoliosis-in-older-women-preliminary-results
#7
Yawara Eguchi, Toru Toyoguchi, Kazuhide Inage, Kazuki Fujimoto, Sumihisa Orita, Kazuyo Yamauchi, Miyako Suzuki, Hirohito Kanamoto, Koki Abe, Masaki Norimoto, Tomotaka Umimura, Masao Koda, Takeo Furuya, Yasuchika Aoki, Kazuhisa Takahashi, Seiji Ohtori
PURPOSE: Advanced glycation end products (AGEs) have been implicated in the pathogenesis of sarcopenia. The objective of the study was to investigate the prevalence of sarcopenia in degenerative lumbar scoliosis (DLS), and the relationship between biochemical markers including major AGEs, pentosidine, and DLS in older women. METHODS: Our study participants were 20 elderly women with idiopathic DLS (mean age 76.4 years, range 56-88). Nineteen age- and sex-matched volunteers (mean age 74...
November 10, 2017: European Spine Journal
https://www.readbyqxmd.com/read/29124406/selective-lateral-pelvic-lymph-node-dissection-a-comparative-study-of-the-robotic-versus-laparoscopic-approach
#8
Hye Jin Kim, Gyu-Seog Choi, Jun Seok Park, Soo Yeun Park, Hee Jae Lee, In Taek Woo, In Kyu Park
BACKGROUND: Lateral pelvic lymph node dissection (LPND) is a challenging procedure due to its technical difficulty and higher incidence of surgical morbidity. We compared short-term outcomes between laparoscopic and robotic LPND in patients with rectal cancer. METHODS: Between May 2006 and December 2014, prospectively collected data from consecutive patients undergoing robotic or laparoscopic total mesorectal excision (TME) with LPND were retrospectively compared...
November 9, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/29122687/is-anatomic-acetabular-orientation-related-to-pelvic-morphology-ct-analysis-of-150-healthy-pelvises
#9
P Sautet, H Giorgi, P Chabrand, P Tropiano, J-N Argenson, S Parratte, B Blondel
BACKGROUND: Links between sagittal spinal alignment and acetabular orientation attract considerable research attention with the goal of optimising prosthetic cup position. However, whether pelvic incidence (PI) is related to anatomic acetabular orientation remains unknown. We therefore conducted a radiological study with the following objectives: to look for correlations between PI and anatomic acetabular parameters; to describe the sacro-pubic angle (SPA), defined by fixed bony pelvic landmarks, and its relations with acetabular inclination; and to determine whether anatomical parameters (PI and SPA) correlate with demographic characteristics...
November 6, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/29112006/modified-lumbosacral-angle-and-modified-pelvic-incidence-as-new-parameters-for-management-of-pediatric-high-grade-spondylolisthesis
#10
Zhenjiang Ma, Changqing Zhao, Kai Zhang, Lin Du, Jianping Tian, Xiaojiang Sun, Jie Zhao
STUDY DESIGN: Retrospective clinical study. OBJECTIVE: We aimed to introduce new parameters that can better describe the pelvic morphology and lumbosacral segmental deformity in children with high-grade spondylolisthesis of the L5 vertebra: modified pelvic incidence (mPI) and modified lumbosacral angle (mLSA). Also, we aimed to establish the mLSA as a convenient, reliable measurement method and criteria to evaluate the reduction of L5 vertebral slippage. SUMMARY OF BACKGROUND DATA: Numerous parameters and methods exist to evaluate segmental deformity and reduction of L5 vertebral slippage, but no definitive standard for accurately and conveniently describing lumbosacral kyphosis and degree of reduction exists...
November 3, 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/29103241/unexpected-significant-uterine-pathological-findings-at-vaginal-hysterectomy-despite-unremarkable-preoperative-workup
#11
Yossi Mizrachi, Samer Tannus, Jacob Bar, Ron Sagiv, Tally Levy, Alexander Condrea, Shimon Ginath
BACKGROUND: Several studies have addressed the issue of undetected uterine pathology in women undergoing hysterectomy for pelvic organ prolapse (POP). However, these studies differ largely with respect to the incidence of malignancy found, study population, and preoperative evaluation. OBJECTIVES: To assess the risk of unexpected pre-malignant and malignant uterine pathological findings after vaginal hysterectomy for POP repair, in a single medical center in Israel...
October 2017: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/29100742/outcome-of-neoadjuvant-chemoradiation-in-mri-staged-locally-advanced-rectal-cancer-retrospective-analysis-of-123-chinese-patients
#12
Shing Fung Lee, Chi Leung Chiang, Francis Ann Shing Lee, Yiu Wah Wong, Chi Ming Poon, Frank Chi Sing Wong, Stewart Yuk Tung
BACKGROUND: For advanced rectal cancer with involved or threatened mesorectal fascia (MRF), current standard is pre-operative long course chemoradiotherapy (PLCRT) with either capecitabine or 5-fluorouracil (5-FU). However, few Chinese data on its clinical outcome are available, especially for those with pelvic MRI staging. METHODS: Between Jan-2009 and Oct-2014, 123 consecutive patients with biopsy proven adenocarcinoma of rectum, all with pelvic MRI staging, selected for PLCRT after multi-disciplinary team discussion were recruited...
November 1, 2017: Journal of the Formosan Medical Association, Taiwan Yi Zhi
https://www.readbyqxmd.com/read/29097007/national-institute-of-allergy-and-infectious-diseases-workshop-report-chlamydia-vaccines-the-way-forward
#13
Guangming Zhong, Robert C Brunham, Luis M de la Maza, Toni Darville, Carolyn Deal
Chlamydia trachomatis (Ct), an intracellular pathogen, is the most common bacterial sexually transmitted infection. In addition to acute cervicitis and urethritis, Ct can lead to serious sequelae of significant public health burden including pelvic inflammatory disease (PID) and infertility. Ct control efforts have not resulted in desired outcomes such as reduced incidence and reinfection, and this highlights the need for the development of an effective Ct vaccine. To this end, NIAID organized a workshop to consider the current status of Ct vaccine research and address critical questions in Ct vaccine design and clinical testing...
October 30, 2017: Vaccine
https://www.readbyqxmd.com/read/29093788/normal-age-adjusted-sagittal-spinal-alignment-is-achieved-with-surgical-correction-in-adolescent-idiopathic-scoliosis
#14
Subaraman Ramchandran, Norah Foster, Akhila Sure, Thomas J Errico, Aaron J Buckland
Study Design: Retrospective analysis. Purpose: Our hypothesis is that the surgical correction of adolescent idiopathic scoliosis (AIS) maintains normal sagittal alignment as compared to age-matched normative adolescent population. Overview of Literature: Sagittal spino-pelvic alignment in AIS has been reported, however, whether corrective spinal fusion surgery re-establishes normal alignment remains unverified. Methods: Sagittal profiles and spino-pelvic parameters of thirty-eight postsurgical correction AIS patients ≤21 years old without prior fusion from a single institution database were compared to previously published normative age-matched data...
October 2017: Asian Spine Journal
https://www.readbyqxmd.com/read/29092805/spontaneous-otorrhagia-after-laparoscopic-pelvic-surgery-a-report-of-two-cases
#15
Keith Basler, Alexander Malone, Matt Carmichael, Osama Hafez, Tapan Padhya, K Paul Boyev
Spontaneous otorrhagia following laparoscopic pelvic surgery is a complication that is rarely reported and incompletely understood. Few case reports have described this phenomenon, though its true incidence is unknown. It has been hypothesized that a combination of extreme patient positioning and abdominal insufflation is the contributing factor. There does not appear to be any untoward consequences and patients can be managed conservatively. We present two cases of spontaneous otorrhagia associated with laparoscopic pelvic surgery, which occurred over a 1-week period at our institution...
November 2, 2017: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/29090359/oblique-retroperitoneal-approach-for-lumbar-interbody-fusion-from-l1-to-s1-in-adult-spinal-deformity
#16
Ki-Tack Kim, Dae-Jean Jo, Sang-Hyun Lee, Eun-Min Seo
In recent years, with advancements in surgical techniques and instrumentation, the lateral lumbar interbody fusion is being used increasingly as an alternative procedure to anterior approach. In this study, we illustrated a oblique retroperitoneal approach for lumbar interbody fusion with one incision site and tilting of the operation table in adult spinal deformity and evaluate the radiographical findings and clinical outcomes of patients treated using this technique. This study included 32 patients scheduled to undergo anterior and posterior long-level fusions for lumbar degenerative kyphosis or degenerative lumbar scoliosis...
October 31, 2017: Neurosurgical Review
https://www.readbyqxmd.com/read/29089122/outcomes-and-patterns-of-relapse-after-definitive-radiation-therapy-for-oligometastatic-cervical-cancer
#17
Matthew S Ning, Vamsi Ahobila, Anuja Jhingran, Shane R Stecklein, Michael Frumovitz, Kathleen M Schmeler, Patricia J Eifel, Ann H Klopp
PURPOSE: Survival rates for women with metastatic cervical cancer are low, with limited management options. Definitive radiation therapy (RT) for oligometastatic disease has led to prolonged survival in other malignancies, but this approach has yet to be systematically studied for cervical cancer. METHODS AND MATERIALS: We evaluated 38 patients who received definitive RT to oligometastatic sites of cervical cancer at a single institution from 2002 to 2015. Patients presented with synchronous (n=9) or metachronous (n=15) oligometastatic disease to supraclavicular (SCV) nodes, or with recurrent disease in mediastinum (n=10) or lung (n=7)...
October 28, 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/29078906/early-thromboprophylaxis-with-low-molecular-weight-heparin-is-safe-in-patients-with-pelvic-fracture-managed-nonoperatively
#18
Faisal Jehan, Terence O'Keeffe, Muhammad Khan, Albert Chi, Andrew Tang, Narong Kulvatunyou, Lynn Gries, Bellal Joseph
INTRODUCTION: Early initiation of thromboprophylaxis is highly desired in pelvic fracture patients, but it is often delayed due to the fear of hemorrhage. Aim of our study was to assess the safety of early initiation of venous thromboprophylaxis in patients with pelvic trauma managed nonoperatively. METHODS: Three-year (2010-2012) retrospective study of trauma patients with pelvic fractures who were managed nonoperatively and received thromboprophylaxis with low-molecular-weight heparin (LMWH)...
November 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/29077603/correlation-of-functional-outcomes-and-sagittal-alignment-after-long-instrumented-fusion-for-degenerative-thoracolumbar-spinal-disease
#19
Kuang-Ting Yeh, Ru-Ping Lee, Ing-Ho Chen, Tzai-Chiu Yu, Kuan-Lin Liu, Cheng-Huan Peng, Jen-Hung Wang, Wen-Tien Wu
STUDY DESIGN: A retrospective function and radiography study of the patients who have received long instrumented thoracolumbar fusion. OBJECTIVE: To investigate the correlation between the sagittal spinopelvic alignment and the functional outcomes after long instrumented fusion for degenerative thoracolumbar spinal disease. SUMMARY OF BACKGROUND DATA: Restoring better sagittal alignment is known as a key factor to spine fusion surgeries. The relationship between function and radiographic results in the elderly group is barely known...
October 26, 2017: Spine
https://www.readbyqxmd.com/read/29072851/cervical-cancer-treated-with-reduced-volume-intensity-modulated-radiation-therapy-base-on-sedlis-criteria-nccn-vs-rtog
#20
Hua-Chun Luo, Gui-Shan Lin, Shao-Guang Liao, Feng-Mei Wang, Hui-Hua Cheng, Jing Feng, Qin Yin, Qun-Hua Chen, Jin-Feng Zhu, Jian-Feng Xu, Dian Wang, Zhi-Chao Fu
OBJECTIVE: This study aimed to evaluate the clinical efficacy of different target volumes in pelvic radiotherapy in postoperative treatment of cervical cancer based on the Sedlis criteria. METHODS: Patients who admitted to our department for postoperative radiotherapy of cervical cancer from December 2001 to December 2011 and met the Sedlis criteria were retrospectively analyzed. The incidences of acute and late radiation injuries, and overall, disease-free, and tumor-specific survival with reduced-volume pelvic and whole-pelvis radiotherapy were evaluated and compared...
October 26, 2017: British Journal of Radiology
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