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Sagittal imbalance

Anna Maria A P Fernandes, Pedro H Vendramini, Renan Galaverna, Nicolas V Schwab, Luciane C Alberici, Rodinei Augusti, Roger F Castilho, Marcos N Eberlin
Mass spectrometry imaging (MSI) of neurotransmitters has so far been mainly performed by matrix-assisted laser desorption/ionization (MALDI) where derivatization reagents, deuterated matrix and/or high resolution, or tandem MS have been applied to circumvent problems with interfering ion peaks from matrix and from isobaric species. We herein describe the application of desorption electrospray ionization mass spectrometry imaging (DESI)-MSI in rat brain coronal and sagittal slices for direct spatial monitoring of neurotransmitters and choline with no need of derivatization reagents and/or deuterated materials...
October 4, 2016: Journal of the American Society for Mass Spectrometry
Junseok Bae, Alexander A Theologis, Jee-Soo Jang, Sang-Ho Lee, Vedat Deviren
STUDY DESIGN: Retrospective analysis of prospectively collected data. OBJECTIVE: To assess global and regional spinal sagittal radiographic parameters in adults with loss of lumbar lordosis ("flatback") before and after walking 10 minutes. SUMMARY OF BACKGROUND DATA: While routine activities of daily living may exacerbate functional disability of spinal sagittal-plane deformity, there is limited understanding of how sagittal parameters and compensatory mechanisms are affected by activity...
September 9, 2016: Spine
H M Yu, K Malhotra, J S Butler, A Patel, M D Sewell, Y Z Li, S Molloy
AIMS: Patients with multiple myeloma (MM) develop deposits in the spine which may lead to vertebral compression fractures (VCFs). Our aim was to establish which spinopelvic parameters are associated with the greatest disability in patients with spinal myeloma and VCFs. PATIENTS AND METHODS: We performed a retrospective cross-sectional review of 148 consecutive patients (87 male, 61 female) with spinal myeloma and analysed correlations between spinopelvic parameters and patient-reported outcome scores...
September 2016: Bone & Joint Journal
Jean Yves Lazennec, Dominique Folinais, Samy Bendaya, Marc Antoine Rousseau, Aidin Eslam Pour
Lumbar stenosis is frequently observed and treated by spine surgeons. The extent of neurological decompression and the potential spinal fixation are the basic concerns when surgery is planned. But this segmented approach to the problem is sometimes insufficient due to the complex functional situations induced by a sagittal imbalance of the patient and the combination of pathologies known as hip-spine or knee-spine syndromes. A total of 373 consecutive patients included from our EOS and clinical data base. Patients were divided in two groups...
October 2016: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
E Kyung Shin, Chi Heon Kim, Chun Kee Chung, Yunhee Choi, Dahae Yim, Whei Jung, Sung Bae Park, Jung Hyeon Moon, Won Heo, Sung-Mi Kim
BACKGROUND CONTEXT: Lumbar spinal stenosis (LSS) is the most common lumbar degenerative disease, and sagittal imbalance is uncommon. Forward-bending posture, which is primarily caused by buckling of the ligamentum flavum, may be improved via simple decompression surgery. PURPOSE: The objectives of this study were to identify the risk factors for sagittal imbalance and to describe the outcomes of simple decompression surgery. STUDY DESIGN: This is a retrospective nested case-control study PATIENT SAMPLE: This was a retrospective study that included 83 consecutive patients (M:F=46:37; mean age, 68...
August 18, 2016: Spine Journal: Official Journal of the North American Spine Society
J C Le Huec, A Cogniet, S Mazas, A Faundez
UNLABELLED: Degenerative de novo scoliosis is commonly present in older adult patients. The degenerative process including disc bulging, facet arthritis, and ligamentum flavum hypertrophy contributes to the appearance of symptoms of spinal stenosis. Idiopathic scoliosis has also degenerative changes that can lead to spinal stenosis. PURPOSE: The aetiology, prevalence, biomechanics, classification, symptomatology, and treatment of idiopathic and degenerative lumbar scoliosis in association with spinal stenosis are reviewed...
October 2016: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
Kenichiro Sakai, Toshitaka Yoshii, Takashi Hirai, Yoshiyasu Arai, Kenichi Shinomiya, Atsushi Okawa
PURPOSE: Cervical sagittal balance has received increased attention as an important determinant of radiological and clinical outcomes. However, no prospective studies have compared the impact of cervical sagittal balance between anterior and posterior surgeries. We previously conducted a prospective study comparing anterior decompression with fusion (ADF) and laminoplasty (LAMP) for degenerative cervical myelopathy (DCM) and reported; however, analysis of cervical alignment within the concept of sagittal balance has yet to be performed, because that concept has recently been proposed...
July 29, 2016: European Spine Journal
Juneyoung Heo, Jae Chil Chang, Hyung-Ki Park
OBJECTIVE: A modified surgical technique of posterior cervical foramintomy called posterior cervical inclinatory foraminotomy (PCIF) was introduced in previous preliminary article. PCIF allows better preservation of facet joint and capsule than conventional techniques. The authors conducted a study to investigate long-term outcomes of PCIF. METHODS: We retrospectively reviewed demographic, radiologic, and clinical data from the patients who underwent PCIFs at our institution...
July 2016: Journal of Korean Neurosurgical Society
Chen Liang, Jianmin Sun, Xingang Cui, Zhensong Jiang, Wen Zhang, Tao Li
BACKGROUND: Spinal sagittal imbalance is a widely acknowledged problem, but there is insufficient knowledge regarding its occurrence. In some patients with lumbar disc herniation (LDH), their symptom is similar to spinal sagittal imbalance. The aim of this study is to illustrate the spinopelvic sagittal characteristics and identity the role of spinal musculature in the mechanism of sagittal imbalance in patients with LDH. METHODS: Twenty-five adults with spinal sagittal imbalance who initially came to our clinic for treatment of LDH, followed by posterior discectomy were reviewed...
2016: BMC Musculoskeletal Disorders
Byung Ho Lee, Jin-Oh Park, Hak-Sun Kim, Kyung-Soo Suk, Sang-Yoon Lee, Hwan-Mo Lee, Jae-Ho Yang, Seong-Hwan Moon
OBJECTIVES: It has been reported that good spinal sagittal alignment reduces the risk of fall and positive sagittal balance is the radiographic parameter that is most highly correlated with adverse health outcomes. However, no reports have demonstrated a change in risk of falling in patients with lumbar spinal stenosis (LSS) according to sagittal balance status. PATIENTS AND METHODS: From September 2013 to October 2014, 141 patients who underwent lumbar spine surgery, including decompression and fusion in-situ for LSS, were enrolled in this study...
September 2016: Clinical Neurology and Neurosurgery
Majid Reza Farrokhi, Fariborz Ghaffarpasand, Mehdi Khani, Mehrnaz Gholami
Cervical spondylotic myelopathy (CSM) is the most common progressive degenerative disease of the spine in geriatric population. Surgery remains the mainstay of the treatment in patients with CSM. The surgical approach should be based on cervical sagittal imbalance. In patients with effective cervical lordosis (fewer than 3 levels of ventral disease), the anterior cervical discectomy and fusion (ACDF) or arthroplasty is preferred. Patients with more than 3 levels of compression are generally treated by laminoplasty, especially with preserved lordotic curvature...
July 4, 2016: World Neurosurgery
Takahito Fujimori, Hai Le, William Schairer, Shinichi Inoue, Motoki Iwasaki, Takenori Oda, Serena S Hu
OBJECTIVES: To examine the relationship between cervical degeneration and spinal alignment by comparing patients with adult spinal deformity versus the control cohort. SUMMARY OF BACKGROUND DATA: The effect of degeneration on cervical alignment has been controversial. METHODS: Cervical and full-length spine radiographs of 57 patients with adult spinal deformity and 78 patients in the control group were reviewed. Adult spinal deformity was classified into 3 types based on the primary characteristics of the deformity: "Degenerative flatback" group, "Positive sagittal imbalance" group, and "Hyperthoracic kyphosis" group...
June 28, 2016: Clinical Spine Surgery
Dong-Gune Chang, Kee-Yong Ha, Young-Hoon Kim, Eun-Whan Lee
STUDY DESIGN: Retrospective comparative study. OBJECTIVE: To compare pedicle subtraction osteotomy (PSO) and iliac fixation (ILF) without osteotomy as methods of correcting lumbar spine deformities due to degenerative sagittal imbalance (DSI) through the evaluation of the changes in spinopelvic alignment. SUMMARY OF BACKGROUND DATA: Many papers have reported the surgical results after PSO and ILF for patients with fixed adult deformities. However, little is known about the difference between PSO and ILF corrections of spinopelvic alignment in adults with DSI...
June 28, 2016: Clinical Spine Surgery
Russell G Strom, Junseok Bae, Jun Mizutani, Frank Valone, Christopher P Ames, Vedat Deviren
OBJECTIVE Lateral interbody fusion (LIF) with percutaneous screw fixation can treat adult spinal deformity (ASD) in the coronal plane, but sagittal correction is limited. The authors combined LIF with open posterior (OP) surgery using facet osteotomies and a rod-cantilever technique to enhance lumbar lordosis (LL). It is unclear how this hybrid strategy compares to OP surgery alone. The goal of this study was to evaluate the combination of LIF and OP surgery (LIF+OP) for ASD. METHODS All thoracolumbar ASD cases from 2009 to 2014 were reviewed...
June 24, 2016: Journal of Neurosurgery. Spine
Sumit Kumar Jain, David Tiernan, Stephen R Kearns
BACKGROUND: The purpose of this retrospective study is to analyze the effect of different variables on union rate and functional outcome in patients who underwent arthroscopic ankle fusion for end-stage arthritis of ankle. METHODS: Clinical records and radiographs were reviewed to evaluate the variables that could predispose patients to non-union and poor functional outcome. Union and functional outcomes were correlated with different variables. RESULTS: Fifty patients had arthroscopic ankle fusion on 52 ankles...
June 2016: Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons
N S Zaborovsky, D A Ptashnikov, D A Mikhailov, O A Smekalenkov, S V Masevnin, O A Lapaeva
AIM: At present, there is no consensus on the approach to treatment of patients older than 60 years of age who have spinal deformity and clinical symptoms. The article describes the effect of two different types of surgery on the quality of life of elderly patients with deformities. MATERIAL AND METHODS: A prospective study included 58 patients operated on at the Verden Russian Research Institute of Traumatology and Orthopedics in the period between 2007 and 2010...
2016: Zhurnal Voprosy Neĭrokhirurgii Imeni N. N. Burdenko
Koji Yamasaki, Masahiro Hoshino, Keita Omori, Hidetoshi Igarashi, Yasuhiro Nemoto, Takashi Tsuruta, Koji Matsumoto, Takanori Iriuchishima, Yasumitsu Ajiro, Hiromi Matsuzaki
STUDY DESIGN: A retrospective study. OBJECTIVE: The purpose of this study was to determine the incidence and risk factors of adjacent segment disease (ASD) after transforaminal inter-body fusion (TLIF) for degenerative lumbar disease. SUMMARY OF BACKGROUND DATA: ASD is a major complication after spinal fusion. Many reports have been published concerning the risk factors for ASD after TLIF. A number of quantitative relationships to spino-pelvic parameters have been established...
June 6, 2016: Spine
P-E Moreau, E Ferrero, G Riouallon, T Lenoir, P Guigui
INTRODUCTION: Lumbar fusion is now a currently accepted treatment for degenerative lumbar spondylolisthesis (DLSP), but may induce adjacent segment degeneration (ASD). The present study hypothesis was that there are radiological parameters associated with ASD. The study objective was to determine predictive factors of ASD. MATERIAL AND METHODS: A single-center retrospective study included patients operated on between 2006 and 2013 for DLSP. Radiological parameters were analyzed on preoperative, immediate postoperative and final follow-up lateral X-ray...
October 2016: Orthopaedics & Traumatology, Surgery & Research: OTSR
Mustafa Erkan Inanmaz, Kamil Cagri Kose, Halil Atmaca, Arif Ozkan, Cengiz Isik, Hakan Basar
STUDY DESIGN: Case series and finite element analysis OBJECTIVE:: To report the clinical results of using intralaminar screw-rod (ILS) constructs as supplements to regular pedicle screw (PS) constructs in "high risk for implant failure" patients and to report the results of a finite element analysis (FEA) of this new instrumentation technique. SUMMARY OF BACKGROUND DATA: Despite advances in surgery and implantation techniques, osteoporosis, obesity, revision surgeries, and neuromuscular conditions (such as parkinson's disease) are challenges against achieving solid arthrodesis and maintaining correction...
June 3, 2016: Clinical Spine Surgery
Steven D Glassman, Mark P Coseo, Leah Y Carreon
BACKGROUND: The durability of adult spinal deformity surgery remains problematic. Revision rates above 20 % have been reported, with a range of causes including wound infection, nonunion and adjacent level pathology. While some of these complications have been amenable to changes in patient selection or surgical technique, Proximal Junctional Kyphosis (PJK) remains an unresolved challenge. This study examines the contributions of non-mechanical factors to the incidence of postoperative sagittal imbalance and PJK after adult deformity surgery...
2016: Scoliosis and Spinal Disorders
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