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https://www.readbyqxmd.com/read/28720885/two-photon-interference-of-polarization-entangled-photons-in-a-franson-interferometer
#1
Heonoh Kim, Sang Min Lee, Osung Kwon, Han Seb Moon
We present two-photon interference experiments with polarization-entangled photon pairs in a polarization-based Franson-type interferometer. Although the two photons do not meet at a common beamsplitter, a phase-insensitive Hong-Ou-Mandel type two-photon interference peak and dip fringes are observed, resulting from the two-photon interference effect between two indistinguishable two-photon probability amplitudes leading to a coincidence detection. A spatial quantum beating fringe is also measured for nondegenerate photon pairs in the same interferometer, although the two-photon states have no frequency entanglement...
July 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28719018/ante-mortem-csf-tau-levels-correlate-with-post-mortem-tau-pathology-in-ftld
#2
D J Irwin, A Lleó, S X Xie, C T McMillan, D Wolk, E B Lee, V M Van Deerlin, L M Shaw, J Q Trojanowski, M Grossman
OBJECTIVE: To test the hypotheses that 1) antemortem cerebrospinal fluid tau levels correlate with postmortem tau pathology in frontotemporal lobar degeneration and 2) tauopathy patients have higher phosphorylated-tau levels compared to TDP-43 proteinopathy patients while accounting for Alzheimer's disease co-pathology. METHODS: Patients had autopsy-confirmed frontotemporal lobar degeneration with tauopathy (n=31), TDP-43 proteinopathy (n=49), or Alzheimer's disease (n=26) with antemortem cerebrospinal fluid...
July 18, 2017: Annals of Neurology
https://www.readbyqxmd.com/read/28716263/exogenous-acrolein-intensifies-sensory-hypersensitivity-after-spinal-cord-injury-in-rat
#3
Breanne Butler, Glen Acosta, Riyi Shi
Acrolein, an α,β-unsaturated aldehyde associated with oxidative stress, is also a major toxic component of tobacco cigarette smoke, which has been reported in the clinic to coincide with the exacerbation of neuropathic pain after SCI. Previous reports have shown that acrolein involvement in spinal cord injury (SCI) is crucial to the development and persistence of neuropathic pain. Through the activation and upregulation of the transient receptor protein ankyrin-1 (TRPA1) cation channel, acrolein is capable of sensitizing the central nervous system in the acute and chronic stages of SCI...
August 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28715405/identification-and-pathological-characterization-of-persistent-asymptomatic-ebola-virus-infection-in-rhesus-monkeys
#4
Xiankun Zeng, Candace D Blancett, Keith A Koistinen, Christopher W Schellhase, Jeremy J Bearss, Sheli R Radoshitzky, Shelley P Honnold, Taylor B Chance, Travis K Warren, Jeffrey W Froude, Kathleen A Cashman, John M Dye, Sina Bavari, Gustavo Palacios, Jens H Kuhn, Mei G Sun
Ebola virus (EBOV) persistence in asymptomatic humans and Ebola virus disease (EVD) sequelae have emerged as significant public health concerns since the 2013-2016 EVD outbreak in Western Africa. Until now, studying how EBOV disseminates into and persists in immune-privileged sites was impossible due to the absence of a suitable animal model. Here, we detect persistent EBOV replication coinciding with systematic inflammatory responses in otherwise asymptomatic rhesus monkeys that had survived infection in the absence of or after treatment with candidate medical countermeasures...
July 17, 2017: Nature Microbiology
https://www.readbyqxmd.com/read/28709081/experiences-with-scramx-alcohol-monitoring-technology-in-100-alcohol-treatment-outpatients
#5
Sheila M Alessi, Nancy P Barnett, Nancy M Petry
BACKGROUND: Transdermal alcohol monitoring technology allows for new research on alcohol use disorders. This study assessed feasibility, acceptability, and adherence with this technology in the context of two clinical research trials. METHODS: Participants were the first 100 community-based alcohol treatment outpatients enrolled in randomized studies that monitored drinking with the secure continuous remote alcohol monitor (SCRAMx(®)) for 12 weeks. Study 1 participants were randomized to usual care (n=36) or usual care with contingency management incentives for treatment attendance (CM-Att; n=30)...
June 28, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28702013/nitrogen-fixation-aligns-with-nifh-abundance-and-expression-in-two-coral-trophic-functional-groups
#6
Claudia Pogoreutz, Nils Rädecker, Anny Cárdenas, Astrid Gärdes, Christian Wild, Christian R Voolstra
Microbial nitrogen fixation (diazotrophy) is a functional trait widely associated with tropical reef-building (scleractinian) corals. While the integral role of nitrogen fixation in coral nutrient dynamics is recognized, its ecological significance across different coral functional groups remains yet to be evaluated. Here we set out to compare molecular and physiological patterns of diazotrophy (i.e., nifH gene abundance and expression as well as nitrogen fixation rates) in two coral families with contrasting trophic strategies: highly heterotrophic, free-living members of the family Fungiidae (Pleuractis granulosa, Ctenactis echinata), and mostly autotrophic coral holobionts with low heterotrophic capacity (Pocilloporidae: Pocillopora verrucosa, Stylophora pistillata)...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28697558/comparative-analysis-of-cortical-microinfarcts-and-microbleeds-using-3-0-tesla-postmortem-magnetic-resonance-images-and-histopathology
#7
Atsushi Niwa, Yuichiro Ii, Akihiro Shindo, Ko Matsuo, Hidehiro Ishikawa, Akira Taniguchi, Shinichi Takase, Masayuki Maeda, Hajime Sakuma, Hiroyasu Akatsu, Yoshio Hashizume, Hidekazu Tomimoto
Microvascular lesions including cortical microinfarctions (CMIs) and cerebral lobar microbleeds (CMBs) are usually caused by cerebral amyloid angiopathy (CAA) in the elderly and are correlated with cognitive decline. However, their radiological-histopathological coincidence has not been revealed systematically with widely used 3-Tesla (3T) magnetic resonance imaging (MRI). The purpose of the present study is to delineate the histopathological background corresponding to MR images of these lesions. We examined formalin-fixed 10-mm thick coronal brain blocks from 10 CAA patients (five were also diagnosed with Alzheimer's disease, three with dementia with Lewy bodies, and two with CAA only) with dementia and six non CAA patients with neurodegenerative disease...
July 5, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28696722/sensitivity-of-electron-transfer-mediated-decay-to-ion-pairing
#8
Marvin Nicolas Pohl, Clemens Richter, Evgeny Lugovoy, Robert Seidel, Petr Slavicek, Emad Flear Aziz, Bernd Abel, Bernd Winter, Uwe Hergenhahn
Ion pairing in electrolyte solutions remains a topic of discussion despite a long history of research. Very recently, nearest-neighbor mediated electronic deexcitation processes of core hole vacancies (Electron Transfer Mediated Decay, ETMD) were proposed to carry a spectral fingerprint of local solvation structure and in particular of contact ion pairs. Here, for the first time, we apply electron-electron coincidence detection to a liquid microjet, and record ETMD spectra of Li 1s vacancies in aqueous solutions of lithium chloride (LiCl) in direct comparison to lithium acetate (LiOAc)...
July 11, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28692943/progressive-increase-in-point-mutations-associates-chloroquine-resistance-even-after-withdrawal-of-chloroquine-use-in-india
#9
Sabyasachi Das, Satyajit Tripathy, Sourav Chattopadhayay, Balaram Das, Santanu Kar Mahapatra, Amiya Kumar Hati, Somenath Roy
Chloroquine (CQ) is highly effective against P. vivax, due to the rapid spread of CQ resistance in P. falciparum parasites; it is no longer the drug of choice against P. falciparum. This study elucidates the scenario of chloroquine efficacy at times that coincided with a new drug policy and especially assessed the chloroquine resistant molecular markers after withdrawal of chloroquine in Kolkata and Purulia, two malaria endemic zones of West Bengal, India. In vitro CQ susceptibility was tested in 781 patients with P...
June 29, 2017: International Journal for Parasitology, Drugs and Drug Resistance
https://www.readbyqxmd.com/read/28692391/harnessing-syndromic-surveillance-emergency-department-data-to-monitor-health-impacts-during-the-2015-special-olympics-world-games
#10
Emily Kajita, Monica Z Luarca, Han Wu, Bessie Hwang, Laurene Mascola
INTRODUCTION: Mass gatherings that attract a large international presence may cause or amplify point-source outbreaks of emerging infectious disease. The Los Angeles County Department of Public Health customized its syndromic surveillance system to detect increased syndrome-specific utilization of emergency departments (EDs) and other medical encounters coincident to the 2015 Special Olympics World Games. MATERIALS AND METHODS: We queried live databases containing data on ED visits, California Poison Control System calls, and Los Angeles County coroner-investigated deaths for increases in daily counts from July 19 to August 6, 2015...
July 2017: Public Health Reports
https://www.readbyqxmd.com/read/28690680/from-grass-to-gas-microbiome-dynamics-of-grass-biomass-acidification-under-mesophilic-and-thermophilic-temperatures
#11
Christian Abendroth, Claudia Simeonov, Juli Peretó, Oreto Antúnez, Raquel Gavidia, Olaf Luschnig, Manuel Porcar
BACKGROUND: Separating acidification and methanogenic steps in anaerobic digestion processes can help to optimize the process and contribute to producing valuable sub-products such as methane, hydrogen and organic acids. However, the full potential of this technology has not been fully explored yet. To assess the underlying fermentation process in more detail, a combination of high-throughput sequencing and proteomics on the acidification step of plant material (grass) at both mesophilic and thermophilic temperatures (37 and 55 °C, respectively) was applied for the first time...
2017: Biotechnology for Biofuels
https://www.readbyqxmd.com/read/28689296/development-of-auditory-sensitivity-in-the-barn-owl
#12
Anna Kraemer, Caitlin Baxter, Alayna Hendrix, Catherine E Carr
Adult barn owl hearing is acute, but development of this sense is not well understood. We, therefore, measured auditory brainstem responses in barn owls from before the onset of hearing (posthatch day 2, or P2) to adulthood (P69). The first consistent responses were detected at P4 for 1 and 2 kHz, followed by responses to 0.5 and 4 kHz at P9, and 5 kHz at P13. Sensitivity to higher frequencies increased with age, with responses to 12 kHz appearing about 2 months after hatching, once the facial ruff was mature...
July 8, 2017: Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology
https://www.readbyqxmd.com/read/28689149/the-response-of-soil-and-stream-chemistry-to-decreases-in-acid-deposition-in-the-catskill-mountains-new-york-usa
#13
Michael R McHale, Douglas A Burns, Jason Siemion, Michael R Antidormi
The Catskill Mountains have been adversely impacted by decades of acid deposition, however, since the early 1990s, levels have decreased sharply as a result of decreases in emissions of sulfur dioxide and nitrogen oxides. This study examines trends in acid deposition, stream-water chemistry, and soil chemistry in the southeastern Catskill Mountains. We measured significant reductions in acid deposition and improvement in stream-water quality in 5 streams included in this study from 1992 to 2014. The largest, most significant trends were for sulfate (SO4(2-)) concentrations (mean trend of -2...
July 6, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28688480/an-intelligent-support-system-for-automatic-detection-of-cerebral-vascular-accidents-from-brain-ct-images
#14
Elmira Hajimani, M G Ruano, A E Ruano
OBJECTIVE: This paper presents a Radial Basis Functions Neural Network (RBFNN) based detection system, for automatic identification of Cerebral Vascular Accidents (CVA) through analysis of Computed Tomographic (CT) images. METHODS: For the design of a neural network classifier, a Multi Objective Genetic Algorithm (MOGA) framework is used to determine the architecture of the classifier, its corresponding parameters and input features by maximizing the classification precision, while ensuring generalization...
July 2017: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/28688405/ion-ion-coincidence-imaging-at-high-event-rate-using-an-in-vacuum-pixel-detector
#15
Jingming Long, Federico J Furch, Judith Durá, Anton S Tremsin, John Vallerga, Claus Peter Schulz, Arnaud Rouzée, Marc J J Vrakking
A new ion-ion coincidence imaging spectrometer based on a pixelated complementary metal-oxide-semiconductor detector has been developed for the investigation of molecular ionization and fragmentation processes in strong laser fields. Used as a part of a velocity map imaging spectrometer, the detection system is comprised of a set of microchannel plates and a Timepix detector. A fast time-to-digital converter (TDC) is used to enhance the ion time-of-flight resolution by correlating timestamps registered separately by the Timepix detector and the TDC...
July 7, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28688391/crf-pepico-double-velocity-map-imaging-photoelectron-photoion-coincidence-spectroscopy-for-reaction-kinetics-studies
#16
Bálint Sztáray, Krisztina Voronova, Krisztián G Torma, Kyle J Covert, Andras Bodi, Patrick Hemberger, Thomas Gerber, David L Osborn
Photoelectron photoion coincidence (PEPICO) spectroscopy could become a powerful tool for the time-resolved study of multi-channel gas phase chemical reactions. Toward this goal, we have designed and tested electron and ion optics that form the core of a new PEPICO spectrometer, utilizing simultaneous velocity map imaging for both cations and electrons, while also achieving good cation mass resolution through space focusing. These optics are combined with a side-sampled, slow-flow chemical reactor for photolytic initiation of gas-phase chemical reactions...
July 7, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28683141/isolation-of-serotype-specific-antibodies-against-dengue-virus-non-structural-protein-1-using-phage-display-and-application-in-a-multiplexed-serotyping-assay
#17
Kebaneilwe Lebani, Martina L Jones, Daniel Watterson, Andrea Ranzoni, Renee J Traves, Paul R Young, Stephen M Mahler
The multidimensional nature of dengue virus (DENV) infections, which can be caused by four distinct serotypes of the virus, complicates the sensitivity of assays designed for the diagnosis of infection. Different viral markers can be optimally detected at different stages of infection. Of particular clinical importance is the early identification of infection, which is pivotal for disease management and the development of blood screening assays. Non-structural protein 1 (NS1) is an early surrogate marker of infection and its detection in serum coincides with detectable viraemia...
2017: PloS One
https://www.readbyqxmd.com/read/28681554/black-scorpionfish-scorpaena-porcus-hemopoiesis-analysis-by-flow-cytometry-and-light-microscopy
#18
Aleksandra Y Andreyeva, Aleksander A Soldatov, Tatiana A Kukhareva
Cell suspensions of head kidney and spleen of black scorpionfish (Scorpaena porcus L.) have been studied using flow cytometry and light microscopy. On the basis of forward scatter (FS) and side scatter (SS) distribution and light microscopy two main types of cells in the hemopoietic organs were identified: "small cells" (5,1-8,9 µm) and "large cells" (10,8-15,3 µm). Subpopulation of small cells was formed by thrombocytes, lymphocytes and elements with functionally inactive nuclei. Euchromatin level in their nuclei was low and acidophilic cytoplasm corresponded to negligible nucleic acids content...
July 6, 2017: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
https://www.readbyqxmd.com/read/28680218/extra-striatal-uptake-of-99m-tc-trodat-1-in-meningioma-detected-on-spect-ct-diagnostic-clue-or-mere-coincidence
#19
Piyush Chandra, Satish Nath
Incidental observation of extra-striatal uptake of (99m)Tc-TRODAT-1 has been reported previously in multiple space-occupying lesions of the brain. We present here a SPECT/CT scan of a 60-year old female with parkinsonism, with normal presynaptic dopaminergic transporters expression and with an intense tracer uptake in a large right-sided frontoparietal meningioma.
July 2017: Indian Journal of Nuclear Medicine: IJNM: the Official Journal of the Society of Nuclear Medicine, India
https://www.readbyqxmd.com/read/28676845/th2-1-hybrid-cells-occurring-in-murine-and-human-strongyloidiasis-share-effector-functions-of-th1-cells
#20
Cristin N Bock, Subash Babu, Minka Breloer, Anuradha Rajamanickam, Yukhti Boothra, Marie-Luise Brunn, Anja A Kühl, Roswitha Merle, Max Löhning, Susanne Hartmann, Sebastian Rausch
Infections by the soil-transmitted threadworm Strongyloides stercoralis affect 30-100 million people worldwide, predominantly in tropic and sub-tropic regions. Here we assessed the T helper cell phenotypes in threadworm-infected patients and experimental murine infections with focus on CD4(+) T cells co-expressing markers of Th2 and Th1 differentiation. We show that mice infected with the close relative S. ratti generate strong Th2 responses characterized by the expansion of CD4(+) GATA-3(+) cells expressing IL-4/-5/-13 in blood, spleen, gut-draining lymph nodes, lung and gut tissue...
2017: Frontiers in Cellular and Infection Microbiology
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