Francisco Alvarez, Pedro Olaechea, Santiago Grau, Mónica Marín, Alfonso Domínguez, José Martínez-Lanao, Dolors Soy, Manuel Alos, María Victoria, Belén Sádaba, Africa Mediavilla, Daniel Fatela
Monitoring plasma concentrations of antimicrobial agents used to treat infection in critically ill patients is one of the recommended strategies for improving clinical outcome. Drug monitoring has a double aim: to limit adverse events and to increase the effectiveness of the drugs. In clinical practice, however, this approach is mainly limited to monitoring plasma concentrations of vancomycin and aminoglycosides, although future extension to other antimicrobial agents would be desirable. Application of this technique varies considerably between hospitals, and this makes interpretation and comparison of the results obtained difficult...
March 2008: Farmacia Hospitalaria