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https://www.readbyqxmd.com/read/28810893/subcutaneous-emphysema-of-the-leg-after-hardware-removal-and-bone-allografting-for-infected-non-union-of-the-distal-femur
#1
Vincenzo Denaro, Umile Giuseppe Longo, Giuseppe Salvatore, Vincenzo Candela, Nicola Maffulli
BACKGROUND: Infected non-unions of the supracondylar region of the femur are uncommon. Even though hardware removal is a common procedure, it may lead to complications, including neurovascular injury, refracture, worsening pain or recurrence of deformity. CASE PRESENTATION: We report on a male who developed subcutaneous emphysema of the leg after hardware removal and bone allografting for an infected non-union of the distal femur. He was managed by debridement of the surgical wound, antibiotic therapy, multiple fasciotomies, and application of a VAC (vacuum-assisted closure) system...
August 15, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28808753/segmental-torsion-assessment-is-a-reliable-method-for-in-depth-analysis-of-femoral-alignment-in-computer-tomography
#2
Peter Wilhelm Ferlic, Armin Runer, Christopher Seeber, Maria Thöni, Gerd Seitlinger, Michael Christian Liebensteiner
PURPOSE: De-rotational osteotomies are indicated in patients with pathologic femoral torsion. However, there is disagreement whether an osteotomy should be performed proximally or distally. Conventionally only the total torsion is measured, which does not allow differentiation between a torsional deformity located in the proximal or distal metaphysis or the diaphysis. The aim of this study is to validate a new multi-level measurement protocol for evaluation of the magnitude of torsion of the respective femoral segments in CT...
August 14, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/28808627/non-ossifying-fibromas-case-series-including-in-uncommon-upper-extremity-sites
#3
Akio Sakamoto, Ryuzo Arai, Takeshi Okamoto, Shuichi Matsuda
AIM: To investigate non-ossifying fibromas (NOFs) common fibrous bone lesions in children that occur in bones of the lower extremities. METHODS: We analyzed 44 cases of NOF including 47 lesions, which were referred with a working diagnosis of neoplastic lesions. Lesions were located in the upper extremities (1 proximal humerus, 1 distal radius) and the lower extremities (25 distal femurs, 12 proximal and 4 distal tibias, and 4 proximal fibulas). RESULTS: Three cases had NOFs in multiple anatomical locations (femur and fibula in 1 case, femur and tibia in 2 cases)...
July 18, 2017: World Journal of Orthopedics
https://www.readbyqxmd.com/read/28806709/in-vivo-kinematics-of-early-stage-osteoarthritic-knees-during-pivot-and-squat-activities
#4
Keisuke Matsuki, Kei O Matsuki, Tomonori Kenmoku, Satoshi Yamaguchi, Takahisa Sasho, Scott A Banks
Kinematic changes have been shown to accompany severe knee osteoarthritis, but no studies have analyzed early-stage osteoarthritic knee kinematics in the transverse plane during functional activities. The purpose of this study was to analyze kinematics of early-stage osteoarthritic knees using model registration techniques. Fifteen early-stage osteoarthritic knees from eight females with a mean age of 52 years old (range, 43-57years old) were involved in this study. A radiologist confirmed with plain radiographs that knees had Kellgren-Lawrence grade-1 or -2 arthritic changes...
August 4, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28806499/hibernating-little-pocket-mice-show-few-seasonal-changes-in-bone-properties
#5
Noellyn Pineda, Marjorie Owen, Claire Tucker, Sam Wojda, Stanley Kitchen, Hal Black, Seth Donahue
Periods of disuse or physical inactivity increase bone porosity and decrease bone mineral density, resulting in a loss of bone mechanical competence in many animals. Although large hibernators like bears and marmots prevent bone loss during hibernation, despite long periods of physical inactivity, some small hibernators do lose bone during hibernation. Little pocket mice (Perognathus longimembris) remain underground during winter hibernation and undergo bouts of torpor and interbout arousals, but the torpor bout duration is shorter than other rodent hibernators...
August 14, 2017: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
https://www.readbyqxmd.com/read/28802725/body-mass-estimation-in-hominoids-age-and-locomotor-effects
#6
M Loring Burgess, Shannon C McFarlin, Antoine Mudakikwa, Michael R Cranfield, Christopher B Ruff
While there are a number of methods available for estimation of body mass in adult nonhuman primates, very few are available for juveniles, despite the potential utility of such estimations in both analyses of fossils and in museum collection based research. Furthermore, because of possible scaling differences, adult based body mass estimation equations may not be appropriate for non-adults. In this study, we present new body mass estimation equations for both adult and immature nonhuman hominoids based on joint and metaphyseal dimensions...
August 9, 2017: Journal of Human Evolution
https://www.readbyqxmd.com/read/28802416/accuracy-of-valgus-osteotomy-using-dynamic-hip-screw
#7
Sunil G Kulkarni, G S Kulkarni, Sushrut Babhulkar, Milind G Kulkarni, Ruta M Kulkarni
BACKGROUND: Non-union of neck femur is a common but difficult situation to manage especially in young adults. There are two main options of arthroplasty or osteotomy. The aim of this study was to assess the results of intertrochanteric valgus osteotomy in non-union femoral neck fractures. PATIENTS AND METHODS: We present a study of 44 cases of neck femur non-union including untreated fractures, late presentations (more than 3 weeks), treated with compression screw, DHS...
August 2017: Injury
https://www.readbyqxmd.com/read/28802414/management-of-resistant-distal-femur-non-unions-with-allograft-strut-and-autografts-combined-with-osteosynthesis-in-a-series-of-22-patients
#8
Raja Bhaskara Kanakeshwar, Dheenadhayalan Jayaramaraju, Devendra Agraharam, Shanmuganathan Rajasekaran
INTRODUCTION AND PURPOSE: Challenges to the surgeon in managing cases of resistant non-union of the distal femur include poor bone stock, disuse osteopenia and joint contractures. Procedures varying from simple bone grafting to megaprosthesis revision have been described. We successfully managed such cases using our technique of combining cortical allograft struts to augment the defect in the femoral condyle coupled with autogenous iliac crest bone grafting and locking plate osteosynthesis...
August 2017: Injury
https://www.readbyqxmd.com/read/28791834/the-effect-of-platelet-rich-plasma-in-bone-tendon-integration
#9
İsmail Ağır, Mahmut Nedim Aytekin, Fatih Küçükdurmaz, Barış Kocaoğlu, Sule Çetinel, Mustafa Karahan
BACKGROUND: The operative reconstruction of a torn or insufficient anterior cruciate ligament has become a routine surgical procedure in orthopedics. The long-term success of an anterior cruciate ligament reconstruction depends on the ability of the graft to heal adequately in a bone tunnel. Investigators studying reconstructions described healing within a tunnel as osseous ingrowth and incorporation. In particular, helping the healing using autologous material for the best integration process was a new idea that helped us to set up this study...
March 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/28782619/differential-responses-of-mechanosensitive-osteocyte-proteins-in-forelimbs-and-hindlimbs-in-hindlimb-unloaded-rats
#10
Corinne E Metzger, Jessica E Brezicha, Jon P Elizondo, S Anand Narayanan, Harry A Hogan, Susan A Bloomfield
Osteocytes are believed to be the primary mechanosensors of bone tissue, signaling to osteoblasts and osteoclasts by releasing specific proteins. Sclerostin, interleukin-6 (IL-6), and insulin-like growth factor-I (IGF-I) are osteocyte proteins that signal to osteoblasts. This study's goals are to determine if osteocyte protein response to mechanical unloading is restricted to the unloaded bone using the hindlimb unloading (HU) rodent model. We also examined tumor necrosis factor-α (TNF-α) due to its interactions with all three osteocyte proteins...
August 3, 2017: Bone
https://www.readbyqxmd.com/read/28782280/orthopaedic-wear-particle-induced-bone-loss-and-exogenous-macrophage-infiltration-is-mitigated-by-local-infusion-of-nf-%C3%AE%C2%BAb-decoy-oligodeoxynucleotide
#11
Tzuhua Lin, Jukka Pajarinen, Akira Nabeshima, Luis A Córdova, Florence Loi, Emmanuel Gibon, Laura Lu, Karthik Nathan, Eemeli Jämsen, Zhenyu Yao, Stuart B Goodman
Excessive production of wear particles from total joint replacements (TJRs) induces chronic inflammation, macrophage infiltration, and consequent bone loss (periprosthetic osteolysis). This inflammation and bone remodeling are critically regulated by the transcription factor NF-κB. We previously demonstrated that inhibition of NF-κB signaling by using the decoy oligodeoxynucleotide (ODN) mitigates polyethylene wear particle-induced bone loss using in vitro and in vivo models. However, the mechanisms of NF-κB decoy ODN action, and in particular its impact on systemic macrophage recruitment, remain unknown...
August 7, 2017: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/28774346/tall-stature-a-difficult-diagnosis
#12
REVIEW
Cristina Meazza, Chiara Gertosio, Roberta Giacchero, Sara Pagani, Mauro Bozzola
Referral for an assessment of tall stature is less common than for short stature. Tall stature is defined as a height more than two standard deviations above the mean for age. The majority of subjects with tall stature show a familial tall stature or a constitutional advance of growth (CAG), which is a diagnosis of exclusion. After a careful physical evaluation, tall subjects may be divided into two groups: tall subjects with normal appearance and tall subjects with abnormal appearance. In the case of normal appearance, the paediatric endocrinologist will have to evaluate the growth rate...
August 3, 2017: Italian Journal of Pediatrics
https://www.readbyqxmd.com/read/28771086/exposure-to-low-dose-x-ray-radiation-alters-bone-progenitor-cells-and-bone-microarchitecture
#13
Florence Lima, Joshua M Swift, Elisabeth S Greene, Matthew R Allen, David A Cunningham, Leslie A Braby, Susan A Bloomfield
Exposure to high-dose ionizing radiation during medical treatment exerts well-documented deleterious effects on bone health, reducing bone density and contributing to bone growth retardation in young patients and spontaneous fracture in postmenopausal women. However, the majority of human radiation exposures occur in a much lower dose range than that used in the radiation oncology clinic. Furthermore, very few studies have examined the effects of low-dose ionizing radiation on bone integrity and results have been inconsistent...
August 3, 2017: Radiation Research
https://www.readbyqxmd.com/read/28768571/a-double-plating-approach-to-distal-femur-fracture-a-clinical-study
#14
Ely L Steinberg, Jacov Elis, Yohai Steinberg, Moshe Salai, Tomer Ben-Tov
BACKGROUND: Locked plating is one of the latest innovative options for treating supracondylar femur fractures with relatively low failure rates. Single lateral plating was often found to have a relative higher failure rate. No clinical studies of double-plating distal femur fixation have thus far been reported. The aim of this study is to present our clinical experience with this surgical approach. PATIENTS AND METHODS: Thirty-two patients (26 females and 6 males, mean age 76 years, range 44-101) were included in the study...
July 25, 2017: Injury
https://www.readbyqxmd.com/read/28768432/effects-of-surgical-factors-on-cartilage-can-be-detected-using-quantitative-magnetic-resonance-imaging-after-anterior-cruciate-ligament-reconstruction
#15
Keiko Amano, Alan K Li, Valentina Pedoia, Matthew F Koff, Aaron J Krych, Thomas M Link, Hollis Potter, Scott Rodeo, Xiaojuan Li, C Benjamin Ma, Sharmila Majumdar
BACKGROUND: Quantitative magnetic resonance (qMR) can be used to measure macromolecules in tissues and is a potential method of observing early cartilage changes in the development of posttraumatic osteoarthritis. Hypothesis/Purpose: We hypothesized that specific patient and surgical factors affecting cartilage matrix composition after anterior cruciate ligament (ACL) reconstruction (ACLR) can be detected using T1ρ and T2 relaxation times. Our purpose was to demonstrate this ability in a multicenter feasibility study...
April 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28757775/an-anatomical-study-of-the-proximal-aspect-of-the-medial-femoral-condyle-to-define-the-proximal-distal-condylar-length
#16
Chia-Ming Chang, Wen-Tien Wu, Kuan-Lin Liu, Kuang-Ting Yeh, Cheng-Huan Peng, Ing-Ho Chen
OBJECTIVE: Despite its possible role in knee arthroplasty, the proximal-distal condylar length (PDCL) of the femur has never been reported in the literature. We conducted an anatomic study of the proximal aspect of the medial femoral condyle to propose a method for measuring the PDCL. MATERIALS AND METHODS: Inspection of dried bone specimens was carried out to assure the most proximal condylar margin (MPCM) as the eligible starting point to measure the PDCL. Simulation surgery was performed on seven pairs of cadaveric knees to verify the clinical application of measuring the PDCL after locating the MPCM...
April 2017: Ci Ji Yi Xue za Zhi, Tzu-chi Medical Journal
https://www.readbyqxmd.com/read/28754245/iatrogenic-trochlear-chondral-defects-after-anterolateral-placement-of-retrograde-femoral-nails
#17
Nicholas N DePhillipo, George F Lebus, Mark E Cinque, Nicholas I Kennedy, Jorge Chahla, Robert F LaPrade
Femoral shaft fractures are common injuries with an incidence of 37.1 per 100,000 person-years in the United States. Retrograde femoral nailing is an increasingly used treatment strategy to manage these injuries, particularly in fractures below stemmed hip prostheses, in supracondylar or distal femur fractures, in fractures in pregnant or obese patients, and when concomitant ipsilateral acetabular/pelvic ring fractures are present. Retrograde fixation has been shown to be a viable option with union rates comparable to antegrade intramedullary nailing...
July 25, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/28748492/calcium-phosphate-hybridized-tendon-grafts-reduce-femoral-bone-tunnel-enlargement-in-anatomic-single-bundle-acl-reconstruction
#18
Hirotaka Mutsuzaki, Tomonori Kinugasa, Kotaro Ikeda, Masataka Sakane
PURPOSE: This study aimed to clarify the effect of calcium phosphate (CaP)-hybridized tendon grafting versus unhybridized tendon grafting on the morphological changes to the bone tunnels at the aperture 1 year after anatomic single-bundle anterior cruciate ligament (ACL) reconstruction. METHODS: Seventy-three patients were randomized to undergo the CaP (n = 37) or the conventional method (n = 36). All patients underwent computed tomography (CT) evaluation 1 week and 1 year post-operatively...
July 26, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28744791/automatic-allograft-bone-selection-through-band-registration-and-its-application-to-distal-femur
#19
Yu Zhang, Lei Qiu, Fengzan Li, Qing Zhang, Li Zhang, Xiaohui Niu
Clinical reports suggest that large bone defects could be effectively restored by allograft bone transplantation, where allograft bone selection acts an important role. Besides, there is a huge demand for developing the automatic allograft bone selection methods, as the automatic methods could greatly improve the management efficiency of the large bone banks. Although several automatic methods have been presented to select the most suitable allograft bone from the massive allograft bone bank, these methods still suffer from inaccuracy...
July 25, 2017: Cell and Tissue Banking
https://www.readbyqxmd.com/read/28743235/magnetic-hyperthermia-enhance-the-treatment-efficacy-of-peri-implant-osteomyelitis
#20
Chih-Hsiang Fang, Pei-I Tsai, Shu-Wei Huang, Jui-Sheng Sun, Jenny Zwei-Chieng Chang, Hsin-Hsin Shen, San-Yuan Chen, Feng Huei Lin, Lih-Tao Hsu, Yen-Chun Chen
BACKGROUND: When bacteria colony persist within a biofilm, suitable drugs are not yet available for the eradication of biofilm-producing bacteria. The aim of this study is to study the effect of magnetic nano-particles-induced hyperthermia on destroying biofilm and promoting bactericidal effects of antibiotics in the treatment of osteomyelitis. METHODS: Sixty 12-weeks-old male Wistar rats were used. A metallic 18G needle was implanted into the bone marrow cavity of distal femur after the injection of Methicillin-sensitive Staphylococcus aureus (MSSA)...
July 25, 2017: BMC Infectious Diseases
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