keyword
MENU ▼
Read by QxMD icon Read
search

Septic peritonitis

keyword
https://www.readbyqxmd.com/read/29035656/clinical-laboratory-and-hemostatic-findings-in-cats-with-naturally-occurring-sepsis
#1
Sigal Klainbart, Limor Agi, Tali Bdolah-Abram, Efrat Kelmer, Itamar Aroch
OBJECTIVE To characterize clinical and laboratory findings in cats with naturally occurring sepsis, emphasizing hemostasis-related findings, and evaluate these variables for associations with patient outcomes. DESIGN Prospective, observational, clinical study. ANIMALS 31 cats with sepsis and 33 healthy control cats. PROCEDURES Data collected included history; clinical signs; results of hematologic, serum biochemical, and hemostatic tests; diagnosis; and outcome (survival vs death during hospitalization or ≤ 30 days after hospital discharge)...
November 1, 2017: Journal of the American Veterinary Medical Association
https://www.readbyqxmd.com/read/28993690/spred2-deficiecy-protects-mice-from-polymicrobial-septic-peritonitis-by-enhancing-inflammation-and-bacterial-clearance
#2
Junya Itakura, Miwa Sato, Toshihiro Ito, Megumi Mino, Soichiro Fushimi, Sakuma Takahashi, Teizo Yoshimura, Akihiro Matsukawa
Sepsis is an infection-induced systemic inflammatory syndrome and a major cause of death for critically ill patients. Here, we examined whether the absence of Sprouty-related EVH1-domain-containing protein 2 (Spred2), a negative regulator of the Ras/Raf/ERK/MAPK pathway, influences host defense against polymicrobial sepsis (PMS) induced by cecal ligation and puncture (CLP). Compared to wild-type mice, Spred2(-/-) mice exhibited higher survival rates with increased level of leukocyte infiltration and local chemokine production and reduced plasma and peritoneal bacterial loads after CLP...
October 9, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28975983/hiv-patient-with-pseudomyxoma-peritonei-of-extra-appendiceal-origin-is-disease-free-and-alive-9-years-after-complete-cytoreductive-surgery
#3
A Tampakis, E C Tampaki, P Alexandrou, K Kontzoglou, G Kouraklis
OBJECTIVE: Pseudomyxoma peritonei (PMP) is a clinical syndrome that is mainly characterized by the presence of mucinous ascites that results from the rupture of a mucin-producing neoplasm. No reports exist so far regarding the management of this syndrome in HIV patients. CASE REPORT: A 54-year old male patient with a diagnosed atypical colitis developed additionally over time a complicated diverticulitis which was initially treated conservatively with antibiotics...
October 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28953653/risk-analysis-of-dialysis-dependent-patients-who-underwent-coronary-artery-bypass-grafting-effects-of-dialysis-modes-on-outcomes
#4
Han-Yan Li, Chih-Hsiang Chang, Cheng-Chia Lee, Victor Chien-Chia Wu, Dong-Yi Chen, Pao-Hsien Chu, Kuo-Sheng Liu, Feng-Chun Tsai, Pyng-Jing Lin, Shao-Wei Chen
Cardiovascular disease is the major morbidity and leading cause of mortality for dialysis-dependent patients. This study aimed to stratify the risk factors and effects of dialysis modes in relation to coronary artery bypass grafting (CABG) surgery among dialysis-dependent patients.This retrospective study enrolled dialysis-dependent patients who underwent CABG from October 2005 to January 2015. All data of demographics, medical history, surgical details, postoperative complications, and in-hospital mortality were analyzed, and patients were categorized as those with or without in-hospital mortality and those with preoperative hemodialysis (HD) or peritoneal dialysis (PD)...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28930916/peripheral-muscle-near-infrared-spectroscopy-nirs-variables-are-altered-early-in-septic-shock
#5
Diego Orbegozo, Fuhong Su, Keliang Xie, Lokmane Rahmania, Fabio Silvio Taccone, Daniel De Backer, Jean-Louis Vincent, Jacques Creteur
BACKGROUND: Non-invasive evaluation of muscle perfusion using near infrared spectroscopy (NIRS) coupled with a vascular occlusion test (VOT) may provide an early and simple marker of altered perfusion and microcirculatory function in sepsis. OBJECTIVE: To compare the time-course of NIRS-derived variables with systemic measures of perfusion in an experimental model of peritonitis. METHODS: Peritonitis was induced in eight anesthetized, mechanically ventilated, adult sheep (24-34 Kg), by injecting autologous feces into the peritoneal cavity...
September 19, 2017: Shock
https://www.readbyqxmd.com/read/28900902/derivation-and-validation-of-a-prognostic-model-for-postoperative-risk-stratification-of-critically-ill-patients-with-faecal-peritonitis
#6
Ascanio Tridente, Julian Bion, Gary H Mills, Anthony C Gordon, Geraldine M Clarke, Andrew Walden, Paula Hutton, Paul A H Holloway, Jean-Daniel Chiche, Frank Stuber, Christopher Garrard, Charles Hinds
BACKGROUND: Prognostic scores and models of illness severity are useful both clinically and for research. The aim of this study was to develop two prognostic models for the prediction of long-term (6 months) and 28-day mortality of postoperative critically ill patients with faecal peritonitis (FP). METHODS: Patients admitted to intensive care units with faecal peritonitis and recruited to the European GenOSept study were divided into a derivation and a geographical validation subset; patients subsequently recruited to the UK GAinS study were used for temporal validation...
September 12, 2017: Annals of Intensive Care
https://www.readbyqxmd.com/read/28892312/-case-report-emphysematous-cystitis
#7
M Piraprez, M Ben Chehida, M Fillet
The emphysematous cystitis is a rare condition characterized by the presence of air in the wall and/or the bladder lumen. The clinical expression of this cystitis is variable. Some patients complain of abdominal pain or urinary symptoms. Other may present only pneumaturia or be totally asymptomatic. This condition is considered as potentially severe since it can lead to an emphysematous pyelonephritis with septicemia and septic shock. Peritonitis may also occur in case of necrosis and perforation of the bladder wall...
September 2017: Revue Médicale de Liège
https://www.readbyqxmd.com/read/28885694/influence-of-preoperative-septic-peritonitis-and-anastomotic-technique-on-the-dehiscence-of-enterectomy-sites-in-dogs-a-retrospective-review-of-210-anastomoses
#8
Daniel J Davis, Ryan M Demianiuk, Jon Musser, Maria Podsiedlik, Joe Hauptman
OBJECTIVE: To determine the influence of preoperative septic peritonitis (PSP) and stapled versus hand-sewn anastomoses on the dehiscence of intestinal resection and anastomosis (IRA). We hypothesized that the incidence of IRA dehiscence would be greater (1) when performed with PSP and (2) for hand-sewn anastomoses. STUDY DESIGN: Retrospective. ANIMAL POPULATIONS: Client-owned dogs at Michigan State University Veterinary Teaching Hospital...
September 8, 2017: Veterinary Surgery: VS
https://www.readbyqxmd.com/read/28877991/activated-protein-c-attenuates-severe-inflammation-by-targeting-vla-3-high-neutrophil-subpopulation-in-mice
#9
Pranita P Sarangi, Hyun-Wook Lee, Yelena V Lerman, Alissa Trzeciak, Eric J Harrower, Alireza R Rezaie, Minsoo Kim
The host injury involved in multiorgan system failure during severe inflammation is mediated, in part, by massive infiltration and sequestration of hyperactive neutrophils in the visceral organ. A recombinant form of human activated protein C (rhAPC) has shown cytoprotective and anti-inflammatory functions in some clinical and animal studies, but the direct mechanism is not fully understood. Recently, we reported that, during endotoxemia and severe polymicrobial peritonitis, integrin VLA-3 (CD49c/CD29) is specifically upregulated on hyperinflammatory neutrophils and that targeting the VLA-3(high) neutrophil subpopulation improved survival in mice...
October 15, 2017: Journal of Immunology: Official Journal of the American Association of Immunologists
https://www.readbyqxmd.com/read/28872080/-role-of-autophagy-in-ameliorating-sepsis-induced-acute-lung-injury-by-allicinin-in-mice
#10
Yue Peng, Yu Jiang, Hao Ou, Wei Xing, Mingshi Yang, Min Gao
To investigate roles of autophagy in ameliorating sepsis-induced acute lung injury by allicinin in mice.
 Methods: A total of 152 male Balb/c mice (8-week old) were randomly divided into a sham group, a septic model group, an allicin treatment group, and an autophagy inhibition group. Septic mouse model was established by cecal ligation and puncture (CLP). Mice in the allicin treatment group were given allicin (30 mg/kg, intra-peritoneal injection) at 6 and 12 h, while those in the autophagy inhibition group were given autophagy inhibitor 3-MA (15 mg/kg, intra-peritoneal injection) at half an hour after allicin administration...
August 28, 2017: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://www.readbyqxmd.com/read/28872079/-mechanisms-for-the-regulatory-effect-of-prostaglandin-e2-prostaglandin-e-receptor-4-on-high-mobility-group-box-1-protein-in-lipopolysaccharide-induced-sepsis-in-mouse-peritoneal-macrophage
#11
Xiaoliang Wang, Yong Zhang, Yanna Si, Yajie Xu, Hongguang Bao, Xiaoming Bai, Jing Leng
To explore the effect of prostaglandin E2 (PGE2) on the expression of high mobility group box-1 protein (HMGB1) in peritoneal macrophages of septic mice and its possible mechanisms.
 Methods: The mouse peritoneal macrophages were isolated and cultured by conventional methods.The model of inflammation was established by using lipopolysaccharide (LPS) to incubate with mouse peritoneal macrophages. The PGE2, prostaglandin E receptor (EP) 4 agonist, EP4 RNAi, and DN.CREB inhibitory plasmid were used to interfere with the LPS-treated mouse peritoneal macrophage...
August 28, 2017: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://www.readbyqxmd.com/read/28862743/negative-pressure-therapy-versus-passive-open-abdominal-drainage-for-the-treatment-of-septic-peritonitis-in-dogs-a-randomized-prospective-study
#12
Anneleen L Spillebeen, Joris H Robben, Rachel Thomas, Jolle Kirpensteijn, Sebastiaan A van Nimwegen
OBJECTIVE: To compare passive open abdominal drainage (POAD) and negative-pressure abdominal drainage (NPAD) using the ABThera™ system in the treatment of septic peritonitis. STUDY DESIGN: Randomized prospective clinical trial. ANIMALS: Dogs (n = 16) with septic peritonitis. METHODS: Dogs with septic peritonitis were randomly assigned to one of two treatment protocols: NPAD versus POAD. Anesthesia time, operating time, duration of drainage, costs, survival, and complications were compared between techniques...
September 1, 2017: Veterinary Surgery: VS
https://www.readbyqxmd.com/read/28846501/rapid-source-control-laparotomy-is-there-a-mortality-benefit
#13
James Vogler, Laura Bagwell, Leslie Hart, Sharon Holmes, Jason Sciaretta, John Mihran Davis
BACKGROUND: The purpose of this study was to determine the influence rapid source-control laparotomy (RSCL) has on the mortality rate in non-trauma patients with intra-abdominal infection. The hypothesis was that RSCL reduces deaths and hospital lengths of stay (LOS) in patients compared with definitive repair and primary fascial closure (PFC). METHODS: The International Classification of Diseases-10 codes for sepsis, gastric and duodenal ulcer perforation or hemorrhage, incisional or ventral hernia with obstruction, intestinal volvulus, ileus with obstruction, diverticulitis with perforation or abscess, vascular disorder of intestine, non-traumatic intestinal perforation, peritoneal abscess, and unspecified peritonitis were used to query the 2015 National Surgical Quality Improvement Project (NSQIP) database for all patients treated with either RSCL or PFC...
October 2017: Surgical Infections
https://www.readbyqxmd.com/read/28818514/effects-of-low-dose-irradiation-on-mice-with-escherichia-coli-induced-sepsis
#14
Kyung-Hee Song, Seung-Youn Jung, Seong-Ho Kho, Sang-Gu Hwang, Hunjoo Ha, Seon Young Nam, Jie-Young Song
Although favorable immune responses to low-dose irradiation (LDI) have been observed in normal mice, i.e., a hormesis effect, little is known about the effects of LDI in infectious diseases. In this study, we examined the effects of LDI on mice with sepsis, a severe and often lethal hyperinflammatory response to bacteria. Female C57BL/6 mice were whole-body irradiated with 10cGy 48h before Escherichia coli infection, and survival, bacterial clearance, cytokines, and antioxidants were quantified. LDI pretreatment significantly increased survival from 46...
October 15, 2017: Toxicology and Applied Pharmacology
https://www.readbyqxmd.com/read/28794357/a-rare-case-of-gastric-ulcer-penetrating-the-pancreas-that-was-successfully-managed-by-conservative-therapy
#15
Narihiro Shibukawa, Shohei Ouchi, Shuji Wakamatsu, Yuhei Wakahara, Nobuyuki Tatsumi, Akira Kaneko
A 62-year-old woman was admitted to our hospital with septic shock due to left submandibular osteomyelitis and cellulitis. Her condition improved following tooth extraction, drainage, and the administration of antibiotics. However, on the 4th day of hospitalization, she went into hemorrhagic shock after defecating a massive tarry stool. Emergency esophagogastroduodenoscopy (EGD) was performed. We found a giant ulcer at the antral greater curvature of the stomach. Computed tomography (CT) revealed that the gastric ulcer had penetrated the pancreas...
September 1, 2017: Internal Medicine
https://www.readbyqxmd.com/read/28792474/the-effects-of-selective-hematopoietic-expression-of-human-il-37-on-systemic-inflammation-and-atherosclerosis-in-ldlr-deficient-mice
#16
Geerte Hoeke, P Padmini S J Khedoe, Janna A van Diepen, Karin Pike-Overzet, Britt van de Ven, Nadia Vazirpanah, Isabel Mol, Pieter S Hiemstra, Frank J T Staal, Rinke Stienstra, Mihai G Netea, Charles A Dinarello, Patrick C N Rensen, Jimmy F P Berbée
The human cytokine interleukin (IL)-37 has potent anti-inflammatory capacities, and hematopoietic cell-specific transgenic overexpression of IL-37 in mice protects against septic shock and colitis. In the present study we investigated the effect of hematopoietic expression of IL-37 on atherosclerosis development under low-grade inflammatory conditions. Low-density lipoprotein receptor (LDLr)-deficient mice were lethally irradiated and transplanted with bone marrow from IL-37-transgenic or control wild-type mice and fed a Western-type diet (WTD; 1% cholesterol) for eight weeks...
August 9, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28763506/the-delta-neutrophil-index-is-a-prognostic-factor-for-postoperative-mortality-in-patients-with-sepsis-caused-by-peritonitis
#17
Jong Wan Kim, Jun Ho Park, Doo Jin Kim, Won Hyuk Choi, Jin Cheol Cheong, Jeong Yeon Kim
INTRODUCTION: The delta neutrophil index (DNI) represents the fraction of circulating immature granulocytes and is a marker of infection and sepsis. Our objective was to evaluate the usefulness of DNI for predicting in-hospital mortality within 30 days after surgery in patients with sepsis caused by peritonitis by means of comparing DNI, white blood cell (WBC) count, neutrophil percentage, and C-reactive protein (CRP) before and after surgery. MATERIALS AND METHODS: We performed a retrospective analysis of demographic, clinical, and laboratory data...
2017: PloS One
https://www.readbyqxmd.com/read/28749085/a-pilot-study-evaluating-the-prognostic-utility-of-platelet-indices-in-dogs-with-septic-peritonitis
#18
Efa A Llewellyn, Jeffrey M Todd, Leslie C Sharkey, Aaron Rendahl
OBJECTIVE: To characterize platelet indices at time of diagnosis of septic peritonitis in dogs and to assess the relationship between platelet parameter data and survival to discharge in dogs treated surgically. DESIGN: Retrospective, observational, descriptive pilot study from 2009 to 2014. SETTING: University teaching hospital. ANIMALS: Forty-eight dogs diagnosed with septic peritonitis were included in this study...
September 2017: Journal of Veterinary Emergency and Critical Care
https://www.readbyqxmd.com/read/28732549/intraperitoneal-lactate-pyruvate-ratio-and-the-level-of-glucose-and-glycerol-concentration-differ-between-patients-surgically-treated-for-upper-and-lower-perforations-of-the-gastrointestinal-tract-a-pilot-study
#19
Jonas E Sabroe, Anne R Axelsen, Mark B Ellebæk, Bjarne Dahler-Eriksen, Niels Qvist
BACKGROUND: Secondary peritonitis is a condition associated with high morbidity and mortality. Continuous postoperative monitoring of patients to ensure timely intervention to treat complications without delay is important for survival and outcome. We aimed to (1) investigate potential differences in postoperative intraperitoneal biomarker levels between patients with upper and lower gastrointestinal tract lesion, and (2) compare postoperative biomarker levels between complicated and uncomplicated patients...
July 21, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28731900/micro-and-macro-circulatory-changes-during-sepsis-and-septic-shock-in-a-rat-model
#20
Tianfeng Hua, Xiaobo Wu, Wei Wang, Hao Li, Jennifer Bradley, Mary Ann Peberdy, Joseph P Ornato, Wanchun Tang
Microcirculation is the motor of sepsis. In the present study, we investigated whether microcirculatory alterations occur prior to changes of systemic hemodynamics in a rat model of cecum ligation and puncture (CLP)-induced sepsis. We further investigated renal microcirculatory changes during sepsis and compared those with buccal microcirculation. Twelve male Sprague-Dawley rats were randomized into a sham control group (n = 6) and a CLP group (n = 6). Perfused microvessel density (PVD) and microvascular flow index (MFI) were evaluated using sidestream dark field (SDF) video microscopy at baseline, 60, 120, 180, 240, 300, and 360 minutes following CLP...
July 20, 2017: Shock
keyword
keyword
58251
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"