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Brian R Davis, Irene Sarosiek, Mohammad Bashashati, Ben Alvarado, Richard W McCallum
INTRODUCTION: Gastroparesis is delayed gastric emptying without mechanical obstruction. Symptomatic improvement can be 50-60% with gastric electrical stimulation. To address delayed gastric emptying, pyloroplasty was added. This study examines the long-term efficacy and safety of simultaneous gastric electrical stimulator implantation and pyloroplasty. METHODS: In this prospective single-arm trial conducted from 2012 to 2015, 27 [23 females; mean age 43 (22-63)] gastroparesis patients who underwent simultaneous gastric electrical stimulator implantation with Heineke-Mikulicz pyloroplasty were studied...
November 28, 2016: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
Ashraf F Al-Faouri, Khaled Y Ajarma, Abdulhamid M Al-Abbadi, Abdullah H Al-Omari, Tariq S Almunaizel, Alaa A Alzu'bi, Ra'ed Y Al-Jarrah, Omar Y Abo-Zaiton
BACKGROUND: To assess and compare performance of the Alvarado score and computed tomography scan in the diagnosis of acute appendicitis at King Hussein Medical Center. METHODS: A total of 320 patients with suspected acute appendicitis were included in this study over a period of 2 years. The Alvarado score was calculated for all of these patients and 112 CT scans were requested selectively by surgeons caring for the patients. The histopathology diagnosis was used as the gold standard against which diagnostic performance of Alvarado score and CT scan were compared...
October 2016: Medical Journal, Armed Forces India
Ryo Mizumoto, Adam T Cristaudo, Nai Kid Lai, Gamini Premaratne, Rasika Hendahewa
BACKGROUND: The presence of mucosal inflammation within appendicectomy specimens is poorly described in the literature, and there is debate regarding the clinical significance of this histological finding. The aim of this study is to correlate clinical and radiological data with histologically confirmed acute mucosal appendicitis (MA). METHODS: A retrospective cohort study was performed to identify all patients who underwent appendicectomy over 5 years at Caboolture Hospital...
November 2, 2016: ANZ Journal of Surgery
Meritxell Ventura-Cots, Mar Concepción, José Antonio Arranz, Macarena Simón-Talero, Maria Torrens, Albert Blanco-Grau, Inma Fuentes, Pilar Suñé, Edilmar Alvarado-Tapias, Cristina Gely, Eva Roman, Beatriz Mínguez, German Soriano, Joan Genescà, Juan Córdoba
BACKGROUND: Ornithine phenylacetate (OP) has been proven effective in lowering ammonia plasma levels in animals, and to be well tolerated in cirrhotic patients. A trial to assess OP efficacy in lowering plasma ammonia levels versus placebo in cirrhotic patients after an upper gastrointestinal bleeding was performed. The primary outcome was a decrease in venous plasma ammonia at 24 hours. METHODS: A total of 38 consecutive cirrhotic patients were enrolled within 24 hours of an upper gastrointestinal bleed...
November 2016: Therapeutic Advances in Gastroenterology
Sergio B Chavez, Luis A Alvarado, Robert Gonzalez
INTRODUCTION: Bipolar I disorder is an illness causing mood shifts that can result in personality and character trait alterations. The relationship between mood and personality and character traits in bipolar I disorder is unclear at this time. METHODS: We conducted a study from February 2009 to March 2010 that included 42 subjects with bipolar I disorder, which was confirmed using the Structured Clinical Interview for DSM-IV Axis I Disorders. Mood was assessed via the Young Mania Rating Scale (YMRS) and the 30-item Clinician-rated Inventory of Depressive Symptomatology (IDS-C)...
2016: Primary Care Companion to CNS Disorders
Pablo Achurra, Antonia Lagos, Ruben Avila, Rodrigo Tejos, Erwin Buckel, Juan Alvarado, Camilo Boza, Nicolas Jarufe, Julian Varas
Introduction Simulated laparoscopy training is limited by its low-quality image. A high-definition (HD) laparoscopic training box was developed under the present necessity of simulating advanced surgery. Objective To describe and test a new HD laparoscopic training box for advanced simulation training. Methods We describe the features and image quality of the new training box. The simulator was tested and then evaluated by a group of 76 expert surgeons using a 4-item questionnaire. To assess the effectiveness of training using this simulation box, 15 general surgery residents were trained to perform a laparoscopic jejuno-jejunostomy in a validated simulation program...
October 10, 2016: Surgical Innovation
Shin Ahn, Hyeji Lee, Wookjin Choi, Ryeok Ahn, Jung-Suk Hong, Chang Hwan Sohn, Dong Woo Seo, Yoon-Seon Lee, Kyung Soo Lim, Won Young Kim
OBJECTIVE: We tried to evaluate the accuracy of the heel drop test in patients with suspected appendicitis and tried to develop a new clinical score, which incorporates the heel drop test and other parameters, for the diagnosis of this condition. METHODS: We performed a prospective observational study on adult patients with suspected appendicitis at two academic urban emergency departments between January and August 2015. The predictive characteristics of each parameter, along with heel drop test results were calculated...
2016: PloS One
Nalin H Dayawansa, Julian D S Segan, Henry H I Yao, Hon I Chong, Paul J Sitzler
BACKGROUND: Normal C-reactive protein (CRP) and white cell count (WCC) are often used to exclude a diagnosis of acute appendicitis in the Emergency Department (ED). Retrospective review of 281 adult patients with acute appendicitis was performed to study the incidence of normal CRP and WCC on admission and examine any possible predisposing factors. METHOD: Retrospective analysis of patient clinical records yielded CRP, WCC, operative diagnosis, time of symptom onset, imaging results and history and examination features...
September 14, 2016: ANZ Journal of Surgery
Juan González Del Castillo, Francisco Javier Ayuso, Victoria Trenchs, Mikel Martinez Ortiz de Zarate, Carmen Navarro, Kinda Altali, Cristina Fernandez, David Huckins, Francisco Javier Martín-Sánchez
OBJECTIVE: Evaluate the diagnostic accuracy of the APPY1 Test alone and in combination with the Alvarado score (AS) to rule out acute appendicitis (AA) in patients presenting to EDs with abdominal pain suspicious for AA. METHODOLOGY: Observational study in a prospective consecutive cohort including all patients from 2 to 20 years with abdominal pain suggestive of AA in four EDs. The APPY1 Test was performed and AS was calculated to determine risk stratification for each patient...
September 9, 2016: Emergency Medicine Journal: EMJ
Ijab Khanafer, Dori-Ann Martin, Tatum P Mitra, Robin Eccles, Mary E Brindle, Alberto Nettel-Aguirre, Graham C Thompson
BACKGROUND: Despite the poor independent test characteristics of the white blood cell count (WBC) and neutrophil count (NC) in identifying appendicitis, common clinical decision supports including the Pediatric Appendicitis Score (PAS) and Alvarado Score (AS), require the WBC and NC values. Moreover, blood tests cause discomfort/pain to children and require time for processing results. Scores based on clinical information alone may be of benefit in the pediatric population. The objective of our study was to determine the test characteristics of the PAS and the AS with and without laboratory investigations (mPAS, mAS respectively) as well as the Lintula Score...
August 30, 2016: BMC Pediatrics
Lucinda Pérez Domínguez, Nieves Cáceres Alvarado, Ángeles Toscano Novella, José Enrique Casal Núñez
BACKGROUND: Colon cancer is the second most frequent cause of death in both genders. Survival has increased since 1980, although this increase has been lower in patients ≥75 years old. We analyzed the results of surgical treatment for this pathology in this group of patients. METHODS: This retrospective, observational and descriptive study analyzed data relating to 315 patients undergoing colon cancer surgery between January 2010 and December 2011. Surgical results (surgical procedure, mean postoperative stay, isolated lymph nodes, postoperative morbidity and mortality) were compared between patients who were <75 and ≥75 years old...
August 26, 2016: ANZ Journal of Surgery
Mónica Ambriz-Tututi, Beatriz Alvarado-Reynoso, René Drucker-Colín
The objective of the present study was to assess the benefits of 1-week repetitive transcranial magnetic stimulation (rTMS) in patients with chronic low back pain (LBP). The visual analogue scale (VAS), Short Form McGill pain questionnaire (SF-MPQ), and Short Form 36 Health Survey were used to evaluate the effect of this treatment. Eighty-two patients diagnosed with LBP were divided randomly into three groups: rTMS-treated group, sham group, and physical therapy-treated group. We observed a significant reduction in VAS and SF-MPQ scores in the rTMS-treated group, but not in the sham group...
August 22, 2016: Bioelectromagnetics
Sven Macco, Bart C Vrouenraets, Steve M M de Castro
BACKGROUND: Acute appendicitis can be difficult to diagnose, especially in children. Appendicitis scoring systems have been developed as a diagnostic tool to improve the decision-making process in patients with suspected acute appendicitis. This study evaluates the Appendicitis Inflammatory Response score, Alvarado score, and Pediatric Appendicitis Score in children suspected of acute appendicitis. METHODS: Data were collected retrospectively. All children younger than 18 years suspected of acute appendicitis who presented to the emergency department between January 2006 and June 2014 were included in this study...
December 2016: Surgery
G Martínez-Mier, S Esquivel-Torres, R A Alvarado-Arenas, A B Ortiz-Bayliss, F A Lajud-Barquín, S Zilli-Hernandez
INTRODUCTION: Liver resection has been associated with high morbidity and mortality, and the most serious complication is liver failure. Patient evaluation is limited to risk scales. The 50-50 criteria and bilirubin peak>7mg/dl have been used as mortality predictors. AIM: The aim of this study was to determine the risk factors associated with morbidity and mortality for liver resection in our population. MATERIAL AND METHODS: A retrospective study was carried out on 51 patients that underwent liver resection...
August 12, 2016: Revista de Gastroenterología de México
M Poca, E Alvarado-Tapias, M Concepción, C Pérez-Cameo, N Cañete, I Gich, C Romero, M Casas, E Román, L Castells, V Vargas, J A Carrión, C Guarner, G Soriano
BACKGROUND: Hospital mortality in patients with spontaneous bacterial peritonitis (SBP) is high despite albumin treatment, particularly in those with worse liver and/or renal function. AIM: To determine the independent predictive factors of in-hospital mortality and to create and validate a predictive model of mortality in patients with SBP. METHODS: We analysed all cirrhotic patients with high-risk SBP (serum urea ≥11 mmol/L and/or serum bilirubin ≥68 μmol/L) between 2001 and 2011...
September 2016: Alimentary Pharmacology & Therapeutics
Samantha Mc Kenzie Stancu, Bogdan Aurelian Popescu, Mircea Beuran
Meckel's Diverticulum is the most common congenital malformation of the gastrointestinal tract with a prevalence of 2 % in the general population, being twice as common and symptomatic in males. Not seldom is the diagnosis made incidentally, upon laparotomy for other intra-abdominal conditions, namely acute appendicitis. Simple Diverticulectomy is the surgical treatment of choice. We present the case of S.M., a 38 year-old male who was admitted to the Surgery Department of the Bucharest Clinical Emergency Hospital for sudden onset of initially periumbilical pain, which later migrated and localized in the right iliac fossa (RIF) accompanied by vomiting after the onset of pain, approximately 24 hours prior to admission...
May 2016: Chirurgia
Ceren Şen Tanrıkulu, Mehmet Akif Karamercan, Yusuf Tanrıkulu, Miraç Öztürk, Yücel Yüzbaşıoğlu, Figen Coşkun
OBJECTIVE: Acute appendicitis (AA) is one of the most common surgical emergencies. Despite extraordinary advances in modern investigations, the accurate diagnosis of AA remains an enigmatic challenge. The aim of this study was to compare and evaluate the diagnostic accuracy of inflammatory parameters [C-reactive protein (CRP), procalcitonin (PCT), erythrocyte sedimentation rate (ESR)], ultrasound (US) and Alvarado score (AS) in reducing the rate of negative appendectomies. MATERIAL AND METHODS: Two hundred seventy-eight patients were included in this study...
2016: Ulusal Cerrahi Dergisi
Alaattin Öztürk, Zuhal Yananlı, Talha Atalay, Ömer Faruk Akıncı
OBJECTIVE: The aim of this study is to compare the effectiveness of computed tomography and Alvarado scoring system in the diagnosis of acute appendicitis in patients who underwent appendectomy with the preliminary diagnosis of acute appendicitis. MATERIAL AND METHODS: One hundred and one patients who underwent appendectomy with the diagnosis of acute appendicitis between January and December 2011 were included in the study. Alvarado scores were calculated, and abdominal tomography scans were obtained for each patient before surgery...
2016: Ulusal Cerrahi Dergisi
Cosme Alvarado-Esquivel, Antonio Sifuentes-Alvarez, Carlos Salas-Martinez
We sought to evaluate the capacity of the Edinburgh Postnatal Depression Scale (EPDS) in discriminating mental disorders other than depression in pregnant women in northern Mexico. Three hundred pregnant women attending prenatal consultations in a public hospital in Durango City, Mexico submitted a validated EPDS and were examined for mental disorders other than depression using the Diagnostic and Statistical Manual of Mental Disorders - 4(th) Ed. (DSM-IV) criteria. Sensitivity and specificity of cut-off points of the EPDS, and positive and negative predictive values were calculated...
May 18, 2016: Mental Illness
M J Brito-Luna, D G Villanueva-Quintero, A K Sandoval-Talamantes, M Fafutis-Morris, O Graciano-Machuca, P E Sanchez-Hernandez, A Alvarado-Navarro
BACKGROUND: Psoriasis is an autoimmune skin disease characterised by proliferation of keratinocytes, primarily due to cytokines Th1 and Th17. This profile is involved in pathogenesis of metabolic syndrome, a frequently found comorbidity in patients with psoriasis. OBJECTIVE: In this study we determine the correlation of levels of pro-inflammatory cytokines TNF-α, IL-23, IL-12, and IL-22 in patients with psoriasis with and without metabolic syndrome and clinically healthy controls...
September 2016: Cytokine
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