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Moral reasoning

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https://www.readbyqxmd.com/read/28343626/the-rat-a-gorical-imperative-moral-intuition-and-the-limits-of-affective-learning
#1
Joshua D Greene
Decades of psychological research have demonstrated that intuitive judgments are often unreliable, thanks to their inflexible reliance on limited information (Kahneman, 2003, 2011). Research on the computational underpinnings of learning, however, indicates that intuitions may be acquired by sophisticated learning mechanisms that are highly sensitive and integrative. With this in mind, Railton (2014) urges a more optimistic view of moral intuition. Is such optimism warranted? Elsewhere (Greene, 2013) I've argued that moral intuitions offer reasonably good advice concerning the give-and-take of everyday social life, addressing the basic problem of cooperation within a "tribe" ("Me vs...
March 23, 2017: Cognition
https://www.readbyqxmd.com/read/28339660/eculizumab-in-secondary-atypical-haemolytic-uraemic-syndrome
#2
Teresa Cavero, Cristina Rabasco, Antía López, Elena Román, Ana Ávila, Ángel Sevillano, Ana Huerta, Jorge Rojas-Rivera, Carolina Fuentes, Miquel Blasco, Ana Jarque, Alba García, Santiago Mendizabal, Eva Gavela, Manuel Macía, Luis F Quintana, Ana María Romera, Josefa Borrego, Emi Arjona, Mario Espinosa, José Portolés, Carolina Gracia-Iguacel, Emilio González-Parra, Pedro Aljama, Enrique Morales, Mercedes Cao, Santiago Rodríguez de Córdoba, Manuel Praga
Background.: Complement dysregulation occurs in thrombotic microangiopathies (TMAs) other than primary atypical haemolytic uraemic syndrome (aHUS). A few of these patients have been reported previously to be successfully treated with eculizumab. Methods.: We identified 29 patients with so-called secondary aHUS who had received eculizumab at 11 Spanish nephrology centres. Primary outcome was TMA resolution, defined by a normalization of platelet count (>150 × 10 9 /L) and haemoglobin, disappearance of all the markers of microangiopathic haemolytic anaemia (MAHA), and improvement of renal function, with a ≥25% reduction of serum creatinine from the onset of eculizumab administration...
February 20, 2017: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/28338944/salience-network-engagement-with-the-detection-of-morally-laden-information
#3
Gunes Sevinc, I Hakan Gurvit, R Nathan Spreng
Moral cognition is associated with activation of the default network, regions implicated in mentalizing about one's own actions or the intentions of others. Yet little is known about the initial detection of moral information. We examined the neural correlates of moral processing during a narrative completion task, which included an implicit moral salience manipulation. During fMRI scanning, participants read a brief vignette and selected the most semantically congruent sentence from two options to complete the narrative...
March 9, 2017: Social Cognitive and Affective Neuroscience
https://www.readbyqxmd.com/read/28325162/-active-anti-smoking-policy-is-a-moral-duty-of-government-responsibility-for-reducing-smoking-lies-with-both-the-individual-and-society
#4
M Verweij
Tobacco discouragement, smoking cessation and tobacco endgame policies are sometimes criticised for being unduly paternalistic: governments should respect citizens' freedom and not take over their individual responsibility for healthy behaviour. In this commentary, I argue that very strict tobacco policies can be justified on multiple grounds, including the harm principle, the public good of maintaining a healthy society, and the reduction of health inequities. The moral reasons governments have to protect people against the harms of smoking do not limit or infringe upon the responsibility of each individual to take care of her own health: responsibility for healthy behaviour is not a zero-sum game...
2017: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/28322171/dopaminergic-modulation-of-sleep-wake-states
#5
Andrea Herrera-Solís, Wendy Herrera-Morales, Luis Núñez-Jaramillo, Oscar Arias-Carrión
The role of dopamine in sleep-wake regulation is associated as a wakefulness-promoting agent. For the clinical treatment of excessive daytime sleepiness, drugs have been commonly used to increase dopamine release. However, sleep disorders or lack of sleep is related to several dopamine-related disorders. The effects of dopaminergic agents, nevertheless, are mediated by two families of dopamine receptors, D1 and D2-like receptors; the first family increases adenylyl cyclase activity and the second inhibits adenylyl cyclase...
March 20, 2017: CNS & Neurological Disorders Drug Targets
https://www.readbyqxmd.com/read/28321688/an-ethical-descriptive-framework-for-judgment-of-actions-and-decisions-in-the-construction-industry-and-engineering-part-i
#6
Omar J Alkhatib, Alaa Abdou
The construction industry is usually characterized as a fragmented system of multiple-organizational entities in which members from different technical backgrounds and moral values join together to develop a particular business or project. The greatest challenge in the construction process for the achievement of a successful practice is the development of an outstanding reputation, which is built on identifying and applying an ethical framework. This framework should reflect a common ethical ground for myriad people involved in this process to survive and compete ethically in today's turbulent construction market...
March 20, 2017: Science and Engineering Ethics
https://www.readbyqxmd.com/read/28299591/dealing-with-the-other-between-the-ethical-and-the-moral-albinism-on-the-african-continent
#7
Elvis Imafidon
Albinism is a global public health issue but it assumes a peculiar nature in the African continent due, in part, to the social stigma faced by persons with albinism (PWAs) in Africa. I argue that there are two essential reasons for this precarious situation. First, in the African consciousness, albinism is an alterity or otherness. The PWA in Africa is not merely a physical other but also an ontological other in the African community of beings, which provides a hermeneutic for the stigmatising separateness or difference of the PWA...
March 15, 2017: Theoretical Medicine and Bioethics
https://www.readbyqxmd.com/read/28292289/at-first-glance-informal-payments-experience-on-track-why-accept-or-refuse-patients-perceive-in-cardiac-surgery-department-of-public-hospitals-northeast-of-iran-2013
#8
Ali Vafaei Najar, Hossein Ebrahimipour, Arefeh Pourtaleb, Habibollah Esmaily, Mehdi Jafari, Zohre Nejatzadegan, Yasamin Molavi Taleghani
BACKGROUND: Patient's Informal payments is among the main source of health care financing in some countries. This paper aimed at determining the patient informal payments and relative factors in Cardiac Surgery Departments (CSD) in hospitals affiliated to Mashhad University of Medical Sciences (MUMS) in 2013. METHODS: In this cross-sectional study, 316 discharged patients were selected using multi-stage sampling. Data gathering tool was a questionnaire which was filled by structured telephone interviews...
March 14, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28288649/medical-termination-of-pregnancy-in-general-practice-in-australia-a-descriptive-interpretive-qualitative-study
#9
Angela J Dawson, Rachel Nicolls, Deborah Bateson, Anna Doab, Jane Estoesta, Ann Brassil, Elizabeth A Sullivan
BACKGROUND: Australian Government approval in 2012 for the use of mifepristone and misoprostol for medical termination of pregnancy (MTOP) allows general practitioners (GPs) to provide early gestation abortion in primary care settings. However, uptake of the MTOP provision by GPs appears to be low and the reasons for this have been unclear. This study investigated the provision of and referral for MTOP by GPs. METHODS: We undertook descriptive-interpretive qualitative research and selected participants for diversity using a matrix...
March 14, 2017: Reproductive Health
https://www.readbyqxmd.com/read/28281090/against-cursory-treatments-in-ethics-of-medical-migration-from-underserved-countries
#10
Yusuf Yuksekdag
In a recent paper, Mpofu, Sen Gupta, and Hays (2016) attempt to outline the obligations of recruiting high-income countries (HICs) and would-be emigrant health workers (HWs) to tackle the effects of mass exodus of health workers from underserved regions. They reconstruct (i) Rawlsian and Kantian global justice approaches to argue for moral obligations of HICs and (ii) an individual justice approach to point to non-enforceable social responsibilities of HWs to assist their compatriots. This critical commentary demonstrates that the argumentation within their individual justice approach is problematic on the basis of three reasons: (1) their discussion under-theorizes and undervalues individual rights and more specifically the right to exit, (2) their argumentation in the latter part, even if problematically, does rather point to moral obligations in lieu of social responsibilities of HWs, and (3) they overlook many other important freedoms, interests, and values pertinent to the issue of retention...
March 9, 2017: Journal of Bioethical Inquiry
https://www.readbyqxmd.com/read/28278744/from-women-s-irresponsibility-to-foetal-patienthood-obstetricians-gynaecologists-perspectives-on-abortion-and-its-stigmatisation-in-italy-and-catalu%C3%A3-a
#11
Silvia De Zordo
This article explores obstetricians-gynaecologists' experiences and attitudes towards abortion, based on two mixed-methods studies respectively undertaken in Italy in 2011-2012, and in Spain (Cataluña) in 2013-2015. Short questionnaires and in-depth interviews were conducted with 54 obstetricians-gynaecologists at 4 hospitals providing abortion care in Rome and Milan, and with 23 obstetricians-gynaecologists at 2 hospitals and one clinic providing abortion care in Barcelona. A medical/moral classification of abortions, from those considered 'more acceptable', both medically and morally - for severe foetal malformations - to the 'least acceptable' ones - repeated 'voluntary abortions', emerged in the discourse of most obstetricians-gynaecologists working in public hospitals, regardless of their religiosity...
March 5, 2017: Global Public Health
https://www.readbyqxmd.com/read/28262929/children-s-sympathy-guilt-and-moral-reasoning-in-helping-cooperation-and-sharing-a-6-year-longitudinal-study
#12
Tina Malti, Sophia F Ongley, Joanna Peplak, Maria P Chaparro, Marlis Buchmann, Antonio Zuffianò, Lixian Cui
This study examined the role of sympathy, guilt, and moral reasoning in helping, cooperation, and sharing in a 6-year, three-wave longitudinal study involving 175 children (Mage 6.10, 9.18, and 12.18 years). Primary caregivers reported on children's helping and cooperation; sharing was assessed behaviorally. Child sympathy was assessed by self- and teacher reports, and self-attributed feelings of guilt-sadness and moral reasoning were assessed by children's responses to transgression vignettes. Sympathy predicted helping, cooperation, and sharing...
November 2016: Child Development
https://www.readbyqxmd.com/read/28258399/beyond-qalys-multi-criteria-based-estimation-of-maximum-willingness-to-pay-for-health-technologies
#13
Erik Nord
The QALY is a useful outcome measure in cost-effectiveness analysis. But in determining the overall value of and societal willingness to pay for health technologies, gains in quality of life and length of life are prima facie separate criteria that need not be put together in a single concept. A focus on costs per QALY can also be counterproductive. One reason is that the QALY does not capture well the value of interventions in patients with reduced potentials for health and thus different reference points...
March 3, 2017: European Journal of Health Economics: HEPAC: Health Economics in Prevention and Care
https://www.readbyqxmd.com/read/28258190/sirt3-deficiency-promotes-lung-fibrosis-by-augmenting-alveolar-epithelial-cell-mitochondrial-dna-damage-and-apoptosis
#14
Renea P Jablonski, Seok-Jo Kim, Paul Cheresh, David B Williams, Luisa Morales-Nebreda, Yuan Cheng, Anjana Yeldandi, Sangeeta Bhorade, Annie Pardo, Moises Selman, Karen Ridge, David Gius, G R Scott Budinger, David W Kamp
Alveolar epithelial cell (AEC) mitochondrial dysfunction and apoptosis are important in idiopathic pulmonary fibrosis and asbestosis. Sirtuin 3 (SIRT3) detoxifies mitochondrial reactive oxygen species, in part, by deacetylating manganese superoxide dismutase (MnSOD) and mitochondrial 8-oxoguanine DNA glycosylase. We reasoned that SIRT3 deficiency occurs in fibrotic lungs and thereby augments AEC mtDNA damage and apoptosis. Human lungs were assessed by using immunohistochemistry for SIRT3 activity via acetylated MnSOD(K68) Murine AEC SIRT3 and cleaved caspase-9 (CC-9) expression were assayed by immunoblotting with or without SIRT3 enforced expression or silencing...
March 3, 2017: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
https://www.readbyqxmd.com/read/28255279/diagnosing-dementia-ethnography-interactional-ethics-and-everyday-moral-reasoning
#15
Alexandra Hillman
This article highlights the contribution of ethnography and qualitative sociology to the ethical challenges that frame the diagnosis of dementia. To illustrate this contribution, the paper draws on an ethnographic study of UK memory clinics carried out between 2012 and 2014. The ethnographic data, set alongside other studies and sociological theory, contest the promotion of a traditional view of autonomy; the limiting of the point of ethical interest to a distinct moment of diagnosis disclosure; and the failure to recognise risk and uncertainty in the building of clinical 'facts' and their communication...
February 2017: Social Theory & Health: STH
https://www.readbyqxmd.com/read/28247200/compulsory-administration-of-oxytocin-does-not-result-in-genuine-moral-enhancement
#16
Vojin Rakić
The question will be raised whether oxytocin can serve as an effective moral enhancer. Different types of moral enhancement will be addressed, one of them being compulsory moral enhancement. It will be argued that oxytocin cannot serve as an effective moral enhancer if its use is being made compulsory. Hence, compulsory administration of oxytocin does not result in genuine moral enhancement. In order to demonstrate this, a stipulation of the main potentially beneficial outcomes of using oxytocin as a moral enhancer will be offered, as well as a discussion of objections to the notion that oxytocin can be an effective moral enhancer...
February 28, 2017: Medicine, Health Care, and Philosophy
https://www.readbyqxmd.com/read/28231439/the-rights-of-drug-treatment-patients-experience-of-addiction-treatment-in-poland-from-a-human-rights-perspective
#17
Justyna Klingemann
BACKGROUND: Drug dependence is a recognized medical condition and therefore, right to health applies in the same way to drug dependence as it does to any other health condition. The human rights in patient care framework - which refers to the application of basic human rights principles in the delivery of health care services - was used to explore the experiences of equality in the dignity and rights protected by Polish law within four different specialist drug treatment settings in Poland...
February 20, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/28220355/dutch-protocols-for-deliberately-ending-the-life-of-newborns-a-defence
#18
Matthew Tedesco
The Groningen Protocol, introduced in the Netherlands in 2005 and accompanied by revised guidelines published in a report commissioned by the Royal Dutch Medical Association in 2014, specifies conditions under which the lives of severely ill newborns may be deliberately ended. Its publication came four years after the Netherlands became the first nation to legalize the voluntary active euthanasia of adults, and the Netherlands remains the only country to offer a pathway to protecting physicians who might engage in deliberately ending the life of a newborn (DELN)...
February 20, 2017: Journal of Bioethical Inquiry
https://www.readbyqxmd.com/read/28219264/we-are-not-gametes-distinguishing-between-abortion-and-contraception
#19
Toni Saad
It is sometimes argued that interruptions of the life's continuum which have the same end result are morally equivalent. In other words, abortion and contraception are ethically identical because both prevent birth and the development of persons. We will examine two major arguments in favour of this thesis: (1) all things that are potential persons have equal moral status. Hence preventing fertilisation of gametes is morally identical to destroying an embryo; (2) all interruptions of the continuous process which leads to the creation of a person are morally equivalent; abortion and contraception are morally indistinguishable...
November 2016: New Bioethics: a Multidisciplinary Journal of Biotechnology and the Body
https://www.readbyqxmd.com/read/28210230/acute-mental-discomfort-associated-with-suicide-behavior-in-a-clinical-sample-of-patients-with-affective-disorders-ascertaining-critical-variables-using-artificial-intelligence-tools
#20
Susana Morales, Jorge Barros, Orietta Echávarri, Fabián García, Alex Osses, Claudia Moya, María Paz Maino, Ronit Fischman, Catalina Núñez, Tita Szmulewicz, Alemka Tomicic
AIM: In efforts to develop reliable methods to detect the likelihood of impending suicidal behaviors, we have proposed the following. OBJECTIVE: To gain a deeper understanding of the state of suicide risk by determining the combination of variables that distinguishes between groups with and without suicide risk. METHOD: A study involving 707 patients consulting for mental health issues in three health centers in Greater Santiago, Chile. Using 345 variables, an analysis was carried out with artificial intelligence tools, Cross Industry Standard Process for Data Mining processes, and decision tree techniques...
2017: Frontiers in Psychiatry
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