keyword
MENU ▼
Read by QxMD icon Read
search

Focal dystonia

keyword
https://www.readbyqxmd.com/read/29460980/quantitative-clinically-relevant-acoustic-measurements-of-focal-embouchure-dystonia
#1
Aimee E Morris, Scott A Norris, Joel S Perlmutter, Jonathan W Mink
BACKGROUND: Focal embouchure dystonia impairs orofacial motor control in wind musicians and causes professional disability. A paucity of quantitative measures or rating scales impedes the objective assessment of treatment efficacy. OBJECTIVES: We quantified specific features of focal embouchure dystonia using acoustic measures and developed a metric to assess severity across multiple domains of symptomatic impairment. METHODS: We recruited 9 brass musicians with and 6 without embouchure dystonia...
February 20, 2018: Movement Disorders: Official Journal of the Movement Disorder Society
https://www.readbyqxmd.com/read/29453996/systematic-review-of-botulinum-toxin-treatment-for-oromandibular-dystonia
#2
Cynthia L Comella
Oromandibular dystonia (OMD) is an isolated focal dystonia that affects the muscles of the jaw, lower face and tongue. It is a rare disorder but is associated with significant impairment in quality of life. Treatment with oral medications has not been successful. Surgical interventions, such as deep brain stimulation, may be of benefit but have not been adequately evaluated. Currently, botulinum toxin (BoNT) injections are regarded as the treatment of choice for OMD. However, the evidence supporting this is not available...
February 14, 2018: Toxicon: Official Journal of the International Society on Toxinology
https://www.readbyqxmd.com/read/29443021/measurement-analysis-of-the-temporal-discrimination-threshold-applied-to-cervical-dystonia
#3
Rebecca B Beck, Eavan M McGovern, John S Butler, Dorina Birsanu, Brendan Quinlivan, Ines Beiser, Shruti Narasimham, Sean O'Riordan, Michael Hutchinson, Richard B Reilly
The temporal discrimination threshold (TDT) is the shortest time interval at which an observer can discriminate two sequential stimuli as being asynchronous (typically 30-50 ms). It has been shown to be abnormal (prolonged) in neurological disorders, including cervical dystonia, a phenotype of adult onset idiopathic isolated focal dystonia. The TDT is a quantitative measure of the ability to perceive rapid changes in the environment and is considered indicative of the behavior of the visual neurons in the superior colliculus, a key node in covert attentional orienting...
January 27, 2018: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29423776/full-recovery-from-drummer-s-dystonia-with-foot-and-arm-symptoms-after-stereotactic-ventro-oral-thalamotomy-a-case-report
#4
Takashi Asahi, Takaomi Taira, Kiyonobu Ikeda, Jiro Yamamoto, Shuji Sato
Ventro-oral (Vo) thalamotomy is effective in patients with focal task-specific dystonias (FTSDs), but only in those with upper-limb symptoms. We describe a patient with drummer's dystonia who completely recovered after Vo thalamotomy. A 37-year-old man who started playing drums at 14 began having difficulty performing fine movements with his right foot when drumming at 22. He experienced right hand cramps while drumming 3 months before visiting our hospital. He was diagnosed with FTSD. Left Vo thalamotomy was performed, which led to complete improvement of symptoms...
February 8, 2018: Acta Neurochirurgica
https://www.readbyqxmd.com/read/29414563/genital-automatisms-reappraisal-of-a-remarkable-but-ignored-symptom-of-focal-seizures
#5
Hava Özlem Dede, Nerses Bebek, Candan Gürses, Leyla Baysal-Kıraç, Betül Baykan, Ayşen Gökyiğit
OBJECTIVES: Genital automatisms (GAs) are uncommon clinical phenomena of focal seizures. They are defined as repeated fondling, grabbing, or scratching of the genitals. The aim of this study was to determine the lateralizing and localizing value and associated clinical characteristics of GAs. METHODS: Three hundred thirteen consecutive patients with drug-resistant seizures who were referred to our tertiary center for presurgical evaluation between 2009 and 2016 were investigated...
February 1, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29408773/dopaminergic-involvement-in-a-drummer-with-focal-dystonia-a-case-study
#6
Tommaso Schirinzi, Simona Scalise, Giulia Di Lazzaro, Rocco Cerroni, Agostino Chiaravalloti, Pamela Lavorenti Figueras, Mariangela Pierantozzi, Antonio Pisani, Alessandro Stefani
Musician's Dystonia (MD) represents an intriguing disorder with rich phenomenology and unclear pathophysiology. We observed a MD affecting left upper limb in a professional drummer. DaT-Scan revealed slight reduced uptake in the right putamen; no extrapyramidal or other neurological signs emerged in 2.5 years of follow up. The case offers insight on dopaminergic involvement in MD.
January 29, 2018: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/29407165/towards-flexible-and-tailored-botulinum-neurotoxin-dosing-regimens-for-focal-dystonia-and-spasticity-insights-from-recent-studies
#7
Jörg Wissel
Botulinum neurotoxin (BoNT) is an effective, well-tolerated, and well-established option for the treatment of dystonic and spastic movement disorders. However, a single approach does not suit all patients, even within one disease indication. The degree of flexibility in treatment protocols is determined by individual product licenses, which often lag behind real-world clinical experience. A number of patient/practitioner surveys conducted recently have highlighted a desire for greater flexibility than that currently approved, both in BoNT doses and in the intervals between consecutive doses...
January 30, 2018: Toxicon: Official Journal of the International Society on Toxinology
https://www.readbyqxmd.com/read/29397587/-occupational-diseases-of-musicians-the-price-of-perfection
#8
Montserrat García Gómez
BACKGROUND: Musicians suffer from a wide range of health problems related to their profession. The aim of this paper was to assess whether work-related musician diseases are included into the Official Spanish List of Occupational Diseases and, if so, to describe and quantify those recognized in recent years. METHODS: The Official Spanish List of Occupational Diseases was searched to identify occupational diseases affecting musicians. We then conducted an incidence study of those occupational diseases recognized under code 29...
January 2018: Archivos de Prevención de Riesgos Laborales
https://www.readbyqxmd.com/read/29348536/surround-inhibition-can-instantly-be-modulated-by-changing-the-attentional-focus
#9
Yves-Alain Kuhn, Martin Keller, Benedikt Lauber, Wolfgang Taube
To further investigate the mechanism of surround inhibition (SI) and to determine whether adopting different attentional strategies might have an impact on the modulation of SI, the effects of adopting an external (EF) or internal focus of attention (IF) on SI and motor performance were investigated. While performing an index flexion with either an EF or IF, transcranial magnetic stimulation was applied at various time points in 14 healthy subjects. When adopting an EF compared to an IF, the results show an improved motor performance (+14...
January 18, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29332077/stereotactic-radiofrequency-lesioning-for-movement-disorders
#10
Takaomi Taira, Shiro Horisawa, Nobuhiko Takeda, Prajakta Ghate
During the past 2 decades, deep brain stimulation (DBS) took over the position of radiofrequency (RF) lesioning of thalamic or pallidal targets for control of movement disorders. Superiority of DBS over RF lesioning is widely accepted, and most neurosurgeons even regard RF lesioning to be old-fashioned and dangerous. Such concepts emerged from the data of old stereotactic operations with ventriculography and without computerized planning. Hardware-related complications are not negligible in long-term DBS therapy, and DBS only controls the symptoms...
2018: Progress in Neurological Surgery
https://www.readbyqxmd.com/read/29332075/patient-evaluation-and-selection-for-movement-disorders-surgery-the-changing-spectrum-of-indications
#11
Steffen Paschen, Günther Deuschl
This report summarizes the state-of-the-art and controversies around patient selection for deep brain stimulation (DBS) for various conditions. Parkinson's disease (PD): several class I studies have shown superiority of DBS over best medical treatment for advanced PD with fluctuations and further inclusion criteria. One class I study suggests that PD patients with early motor complications might gain more quality of life if operated within 3 years after the onset of fluctuations. The subthalamic nucleus (STN) is still the standard target...
2018: Progress in Neurological Surgery
https://www.readbyqxmd.com/read/29316781/quantitative-assessment-of-hand-dysfunction-in-patients-with-early-parkinson-s-disease-and-focal-hand-dystonia
#12
Deepa Kandaswamy, MuthuKumar M, Mathew Alexander, Krishna Prabhu, Mahasampath Gowri S, Srinivasa Babu Krothapalli
OBJECTIVE: Motor impairments related to hand function are common symptoms in patients with movement disorders, such as Parkinson's disease (PD) and focal hand dystonia (FHD). However, hand dysfunction has not been quantitatively assessed as a clinical tool for screening patient groups from healthy controls (HCs). The aim of our study was 1) to quantitatively assess hand dysfunction in patients with PD and FHD and its usefulness as a screening tool 2) to grade disease severity in PD and FHD based on hand dysfunction...
January 2018: Journal of Movement Disorders
https://www.readbyqxmd.com/read/29288226/progressive-delayed-hemidystonia-following-clinically-mild-traumatic-brain-injury
#13
Swaleha N Nadaf, Rahul T Chakor, Kaumil Vipul Kothari, Haresh Bharote
A 16-year-old boy presented with progressive left hemidystonia over 3 years. The possibilities of symptomatic hemidystonia due to focal lesions such as infarct (vasculitis), tumours, tuberculoma, arteriovenous malformations or heredodegenerative disorders such as Wilson disease were considered. Imaging showed a peculiar scar involving right basifrontal region extending upto anterior, centromedian and dorsomedial nuclei of thalamus due to blowout fracture of roof of orbit. This scar was responsible for progressive left hemidystonia...
December 28, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/29286305/muscle-selection-for-focal-limb-dystonia
#14
REVIEW
Barbara Illowsky Karp, Katharine Alter
Selection of muscles for botulinum toxin injection for limb dystonia is particularly challenging. Limb dystonias vary more widely in the pattern of dystonic movement and involved muscles than cervical dystonia or blepharospasm. The large variation in how healthy individuals perform skilled hand movements, the large number of muscles in the hand and forearm, and the presence of compensatory actions in patients with dystonia add to the complexity of choosing muscles for injection. In this article, we discuss approaches to selecting upper and lower extremity muscles for chemodenervation treatment of limb dystonia...
December 29, 2017: Toxins
https://www.readbyqxmd.com/read/29279192/the-prevalence-of-prkra-mutations-in-idiopathic-dystonia
#15
Camila Oliveira Dos Santos, Francisco Pereira da Silva-Júnior, Renato David Puga, Egberto Reis Barbosa, Sonia Maria Cesar Azevedo Silva, Vanderci Borges, João Carlos Papaterra Limongi, Maria Sheila Guimarães Rocha, Henrique Ballalai Ferraz, Patricia de Carvalho Aguiar
INTRODUCTION: DYT-PRKRA (DYT16) is considered a rare cause of dystonia-parkinsonism. The significance of this gene as a cause of dystonia and its phenotypical characterization must be determined in larger cohorts. We aimed to investigate the role of PRKRA in patients with dystonia. METHODS: We sequenced PRKRA in 153 unrelated Brazilian patients with idiopathic dystonia. The frequency of novel missense variants was investigated in healthy Brazilian controls and in public databases...
December 13, 2017: Parkinsonism & related Disorders
https://www.readbyqxmd.com/read/29238711/long-term-dose-stability-of-onabotulinumtoxina-injection-for-adductor-spasmodic-dysphonia-a-19-year-single-institution-experience
#16
Paul Paddle, Inna Husain, Christine Moniz, Scott Turner, Ramon Arturo Franco
Objectives: Adductor spasmodic dysphonia (AdSD) is a focal dystonia predominantly involving the laryngeal adductor muscles. AdSD is reported to be a largely non-progressive neurological disorder, though fluctuations in symptom severity do occur. Repeated laryngeal onabotulinumtoxinA (BTX-A) injections are the primary management for AdSD. A number of studies have demonstrated long-term dose stability as evidence of this long-term disease stability. Methods: A retrospective review was performed on all patients undergoing BTX-A injections for AdSD from April 1994 to September 2013 by a single laryngologist at a tertiary referral laryngology center...
2017: Frontiers in Surgery
https://www.readbyqxmd.com/read/29234300/temporal-discrimination-mechanisms-and-relevance-to-adult-onset-dystonia
#17
REVIEW
Antonella Conte, Eavan M McGovern, Shruti Narasimham, Rebecca Beck, Owen Killian, Sean O'Riordan, Richard B Reilly, Michael Hutchinson
Temporal discrimination is the ability to determine that two sequential sensory stimuli are separated in time. For any individual, the temporal discrimination threshold (TDT) is the minimum interval at which paired sequential stimuli are perceived as being asynchronous; this can be assessed, with high test-retest and inter-rater reliability, using a simple psychophysical test. Temporal discrimination is disordered in a number of basal ganglia diseases including adult-onset dystonia, of which the two most common phenotypes are cervical dystonia and blepharospasm...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/29231958/medical-issues-in-playing-the-oboe-a-literature-review
#18
REVIEW
Sofia Banzhoff, Maria Del Mar Ropero, Gabriele Menzel, Tatjana Salmen, Manfred Gross, Philipp P Caffier
Playing a musical instrument can affect physical and mental health. A literature review was conducted to determine the prevalence of health problems among oboists, which medical conditions can be caused or exacerbated by playing, whether oboe playing can be a protective factor, and whether recommendations are possible as to who should or should not play the oboe. Searches in 7 databases (Medline, Embase, Cochrane Library, Web of Science, SocIndex, PsyIndex, Psychinfo) yielded a total of 950 studies; after exclusion of duplicates and those not meeting eligibility criteria, 37 articles were selected for final analysis...
December 2017: Medical Problems of Performing Artists
https://www.readbyqxmd.com/read/29230798/botulinum-toxin-type-a-therapy-for-cervical-dystonia
#19
REVIEW
Mafalda Castelão, Raquel E Marques, Gonçalo S Duarte, Filipe B Rodrigues, Joaquim Ferreira, Cristina Sampaio, Austen P Moore, João Costa
BACKGROUND: This is an update of a Cochrane Review first published in 2005. Cervical dystonia is the most common form of focal dystonia and is a highly disabling movement disorder characterised by involuntary, usually painful, head posturing. Currently, botulinum toxin type A (BtA) is considered the first line therapy for this condition. OBJECTIVES: To compare the efficacy, safety, and tolerability of botulinum toxin type A (BtA) versus placebo in people with cervical dystonia...
December 12, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29208327/botulinum-toxin-a-for-patients-with-orofacial-dystonia-prospective-observational-single-centre-study
#20
G Ruiz-de-León-Hernández, R-M Díaz-Sánchez, D Torres-Lagares, E Hernández-Pacheco, M González-Martín, M-A Serrera-Figallo
The objective of this study was to demonstrate the efficacy of intramuscular botulinum toxin type A (BTX-A) as a method of controlling the symptoms of focal facial dystonia. A prospective, longitudinal, observational, pre-post (case-series) single-centre study was conducted over a period of 3 months, involving 30 patients with focal dystonia. The patients were enrolled on a first-come, first-served basis. For all patients, the abnormal movements were evaluated using the Abnormal Involuntary Movement Scale (AIMS)...
March 2018: International Journal of Oral and Maxillofacial Surgery
keyword
keyword
58211
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"