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Attention deficit disorder pregnancy

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https://www.readbyqxmd.com/read/28428763/adhd-lifestyles-and-comorbidities-a-call-for-an-holistic-perspective-from-medical-to-societal-intervening-factors
#1
REVIEW
Simon Weissenberger, Radek Ptacek, Martina Klicperova-Baker, Andreja Erman, Katerina Schonova, Jiri Raboch, Michal Goetz
The review examines Attention Deficit Hyperactivity Disorder (ADHD in its Child and Adult form) and its various presentations (Hyperactive Impulsive, Inattentive, and Combined) with a particular focus on environmental (incl. social factors), lifestyles and comorbidities. It is argued that ADHD is best understood in a holistic and interactive context and a vast empirical literature is presented to illustrate the point: Environmental factors include stress in general as well as exposure to toxins (phthalates, bisphenol A)...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28418479/associations-of-maternal-antidepressant-use-during-the-first-trimester-of-pregnancy-with-preterm-birth-small-for-gestational-age-autism-spectrum-disorder-and-attention-deficit-hyperactivity-disorder-in-offspring
#2
Ayesha C Sujan, Martin E Rickert, A Sara Öberg, Patrick D Quinn, Sonia Hernández-Díaz, Catarina Almqvist, Paul Lichtenstein, Henrik Larsson, Brian M D'Onofrio
Importance: Prenatal antidepressant exposure has been associated with adverse outcomes. Previous studies, however, may not have adequately accounted for confounding. Objective: To evaluate alternative hypotheses for associations between first-trimester antidepressant exposure and birth and neurodevelopmental problems. Design, Setting, and Participants: This retrospective cohort study included Swedish offspring born between 1996 and 2012 and followed up through 2013 or censored by death or emigration...
April 18, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28414486/girls-with-childhood-adhd-as-adults-cross-domain-outcomes-by-diagnostic-persistence
#3
Elizabeth B Owens, Christine Zalecki, Peter Gillette, Stephen P Hinshaw
OBJECTIVE: To ascertain adult outcomes in 10 domains reflecting symptomatology (internalizing, externalizing, self-injury, substance use), attainment (education, employment), and impairment (health, social, driving, overall) as a function of both childhood diagnosis of attention-deficit/hyperactivity disorder (ADHD) and persistence of ADHD symptoms across time. METHOD: We prospectively followed 140 grade-school-aged girls with rigorously diagnosed childhood ADHD and 88 age- and ethnicity-matched comparison girls for 16 years...
April 17, 2017: Journal of Consulting and Clinical Psychology
https://www.readbyqxmd.com/read/28413441/prevalence-and-associated-factors-of-attention-deficit-hyperactivity-disorder-adhd-among-ugandan-children-a-cross-sectional-study
#4
Joan Wamulugwa, Angelina Kakooza, Sabrina Bakeera Kitaka, Joyce Nalugya, Mark Kaddumukasa, Shirley Moore, Martha Sajatovic, Elly Katabira
BACKGROUND: Attention deficit hyperactivity disorder (ADHD) is a common neuropsychiatric disorder among the children. The burden of ADHD or its associated factors in Uganda are not known. The objective of this study was to determine the prevalence and the associated factors of ADHD among children attending the neurology and psychiatry clinics at Mulago National Referral Hospital. METHODS: Using the disruptive behavior scale (45 items), we investigated the presence of ADHD symptoms among children attending Mulago Hospital...
2017: Child and Adolescent Psychiatry and Mental Health
https://www.readbyqxmd.com/read/28348386/perinatal-risk-factors-in-tourette-s-and-chronic-tic-disorders-a-total-population-sibling-comparison-study
#5
G Brander, M Rydell, R Kuja-Halkola, L Fernández de la Cruz, P Lichtenstein, E Serlachius, C Rück, C Almqvist, B M D'Onofrio, H Larsson, D Mataix-Cols
Adverse perinatal events may increase the risk of Tourette's and chronic tic disorders (TD/CTD), but previous studies have been unable to control for unmeasured environmental and genetic confounding. We aimed to prospectively investigate potential perinatal risk factors for TD/CTD, taking unmeasured factors shared between full siblings into account. A population-based birth cohort, consisting of all singletons born in Sweden in 1973-2003, was followed until December 2013. A total of 3 026 861 individuals were identified, 5597 of which had a registered TD/CTD diagnosis...
March 28, 2017: Molecular Psychiatry
https://www.readbyqxmd.com/read/28332006/prenatal-nicotine-exposure-decreases-the-release-of-dopamine-in-the-medial-frontal-cortex-and-induces-atomoxetine-responsive-neurobehavioral-deficits-in-mice
#6
Tursun Alkam, Takayoshi Mamiya, Nami Kimura, Aya Yoshida, Daisuke Kihara, Yuki Tsunoda, Yuki Aoyama, Masayuki Hiramatsu, Hyoung-Chun Kim, Toshitaka Nabeshima
Increased risk of attention-deficit/hyperactivity disorder (AD/HD) is partly associated with the early developmental exposure to nicotine in tobacco smoke. Emerging reports link tobacco smoke exposure or prenatal nicotine exposure (PNE) with AD/HD-like behaviors in rodent models. We have previously reported that PNE induces cognitive behavioral deficits in offspring and decreases the contents of dopamine (DA) and its turnover in the prefrontal cortex (PFC) of offspring It is well known that the dysfunction of DAergic system in the brain is one of the core factors in the pathophysiology of AD/HD...
March 23, 2017: Psychopharmacology
https://www.readbyqxmd.com/read/28283834/risk-factors-for-comorbid-oppositional-defiant-disorder-in-attention-deficit-hyperactivity-disorder
#7
Siri D S Noordermeer, Marjolein Luman, Wouter D Weeda, Jan K Buitelaar, Jennifer S Richards, Catharina A Hartman, Pieter J Hoekstra, Barbara Franke, Dirk J Heslenfeld, Jaap Oosterlaan
Oppositional defiant disorder (ODD) is highly prevalent in attention-deficit/hyperactivity disorder (ADHD). Individuals with both ADHD and ODD (ADHD + ODD) show a considerably worse prognosis compared with individuals with either ADHD or ODD. Therefore, identification of risk factors for ADHD + ODD is essential and may contribute to the development of (early) preventive interventions. Participants were matched for age, gender, and ADHD-subtype (diagnostic groups), and did not differ in IQ. Predictors included pre- and perinatal risk factors (pregnancy duration, birth weight, maternal smoking during pregnancy), transgenerational factors (parental ADHD; parental warmth and criticism in diagnostic groups), and postnatal risk factors (parental socioeconomic status [SES], adverse life events, deviant peer affiliation)...
March 10, 2017: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/28276257/pre-conceptual-and-prenatal-supplementary-folic-acid-and-multivitamin-intake-behavioral-problems-and-hyperkinetic-disorders-a-study-based-on-the-danish-national-birth-cohort-dnbc
#8
Jasveer Virk, Zeyan Liew, Jørn Olsen, Ellen A Nohr, Janet M Catov, Beate Ritz
OBJECTIVE: To evaluate whether early folic acid or multivitamin supplementation during pregnancy prevents diagnosis of hyperkinetic disorders (HKD), treatment for attention deficit hyperactivity disorder (ADHD), and ADHD-like behaviors reported by parents participating in the DNBC for children at age 7. METHODS: HKD diagnosis and ADHD medication use data were obtained from the Danish National Hospital, Central Psychiatric and Pharmaceutical registers. We estimated hazard ratios (HRs) for HKD diagnosis and ADHD medication use and risk ratios (RRs) for parent-reported ADHD behavior collected with the Strength and Difficulties Questionnaire (SDQ), comparing children whose mothers took folic acid or multivitamin supplements early in pregnancy defined as starting periconceptionally (4 weeks prior to their last menstrual period (LMP)) through 8 weeks after their LMP (4-8 weeks), to children whose mothers indicated no supplement use for the same entire period...
March 9, 2017: Nutritional Neuroscience
https://www.readbyqxmd.com/read/28269805/experiences-of-employed-women-with-attention-deficit-hyperactive-disorder-a-phenomenological-study
#9
N Schreuer, R Dorot
BACKGROUND: Employees with attention-deficit/hyperactivity disorder (ADHD) face various risks in the workplace. Little is known of the specific challenges women with ADHD experience. OBJECTIVE: To explore the experiences of working women with ADHD and learn the strategies and accommodations that facilitate their maintaining employment. METHOD: Qualitative phenomenological approach was used to echo women's subjective perceptions and experiences representing their daily interactions in their workplace...
February 27, 2017: Work: a Journal of Prevention, Assessment, and Rehabilitation
https://www.readbyqxmd.com/read/28259004/age-dependent-role-of-pre-and-perinatal-factors-in-interaction-with-genes-on-adhd-symptoms-across-adolescence
#10
Djûke M Brinksma, Pieter J Hoekstra, Barbara van den Hoofdakker, Annelies de Bildt, Jan K Buitelaar, Catharina A Hartman, Andrea Dietrich
Little is known about the effects of risk factors on attention-deficit/hyperactivity disorder (ADHD) symptom over time. Here, we longitudinally studied the role of candidate genes, pre- and perinatal factors, and their interactions on ADHD symptoms between ages 10 and 18 years. Subjects were part of the general population or clinic-referred cohort of the TRacking Adolescents' Individual Lives Survey (n = 1667). At mean ages of 11.1 (T1), 13.4 (T2), and 16.2 years (T3), ADHD symptoms were assessed with the Child Behavior Checklist...
February 21, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/28258320/further-evidence-for-the-role-of-pregnancy-induced-hypertension-and-other-early-life-influences-in-the-development-of-adhd-results-from-the-idefics-study
#11
Hermann Pohlabeln, Stefan Rach, Stefaan De Henauw, Gabriele Eiben, Wencke Gwozdz, Charalampos Hadjigeorgiou, Dénes Molnár, Luis A Moreno, Paola Russo, Toomas Veidebaum, Iris Pigeot
The aim of this study is to investigate whether in addition to established early risk factors other, less studied pre-, peri-, and postnatal influences, like gestational hypertension or neonatal respiratory disorders and infections, may increase a child's risk of developing attention-deficit/hyperactivity disorders (ADHD). In the IDEFICS study more than 18,000 children, aged 2-11.9 years, underwent extensive medical examinations supplemented by parental questionnaires on pregnancy and early childhood. The present analyses are restricted to children whose parents also completed a supplementary medical questionnaire (n = 15,577), including the question whether or not the child was ever diagnosed with ADHD...
March 3, 2017: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/28209774/methyl-donor-supplementation-alters-cognitive-performance-and-motivation-in-female-offspring-from-high-fat-diet-fed-dams
#12
Sarah E McKee, Nicola M Grissom, Christopher T Herdt, Teresa M Reyes
During gestation, fetal nutrition is entirely dependent on maternal diet. Maternal consumption of excess fat during pregnancy has been linked to an increased risk of neurologic disorders in offspring, including attention deficit/hyperactivity disorder, autism, and schizophrenia. In a mouse model, high-fat diet (HFD)-fed offspring have cognitive and executive function deficits as well as whole-genome DNA and promoter-specific hypomethylation in multiple brain regions. Dietary methyl donor supplementation during pregnancy or adulthood has been used to alter DNA methylation and behavior...
February 16, 2017: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
https://www.readbyqxmd.com/read/28185095/in-utero-exposure-to-%C3%AE-2-adrenergic-receptor-agonist-and-attention-deficit-hyperactivity-disorder-in-children
#13
Hong Liang, Jianping Chen, Maohua Miao, Jakob Christensen, Søren Dalsgaard, Wei Yuan, Jiong Li
We aimed to examine the association between in utero exposure to β2AA and risk of attention-deficit/hyperactivity disorder (ADHD). We established a cohort of 672,265 children born from 1998 to 2008 in Denmark. Children were categorized as exposed if their mothers had redeemed a prescription of β2AA in pregnancy (from 30 days prior to conception until delivery). We identified children diagnosed with ADHD in the Danish National Hospital Register for the first time after his/her third birthday. Log-linear Poisson regression was used to estimate adjusted incidence rate ratio (aIRR) of ADHD...
February 9, 2017: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/28168960/sex-specific-neurodevelopmental-programming-by-placental-insulin-receptors-on-stress-reactivity-and-sensorimotor-gating
#14
Stefanie L Bronson, Jennifer C Chan, Tracy L Bale
BACKGROUND: Diabetes, obesity, and overweight are prevalent pregnancy complications that predispose offspring to neurodevelopmental disorders, including autism, attention-deficit/hyperactivity disorder, and schizophrenia. Although male individuals are three to four times more likely than female individuals to develop these disorders, the mechanisms driving the sex specificity of disease vulnerability remain unclear. Because defective placental insulin receptor (InsR) signaling is a hallmark of pregnancy metabolic dysfunction, we hypothesized that it may be an important contributor and novel mechanistic link to sex-specific neurodevelopmental changes underlying disease risk...
December 30, 2016: Biological Psychiatry
https://www.readbyqxmd.com/read/28138005/smoking-in-pregnancy-and-child-adhd
#15
Kristin Gustavson, Eivind Ystrom, Camilla Stoltenberg, Ezra Susser, Pål Surén, Per Magnus, Gun Peggy Knudsen, George Davey Smith, Kate Langley, Michael Rutter, Heidi Aase, Ted Reichborn-Kjennerud
BACKGROUND AND OBJECTIVE: There is a well-documented association between maternal smoking during pregnancy and offspring attention-deficit/hyperactivity disorder (ADHD). The degree to which this reflects causal intrauterine effects or is due to unmeasured confounding is not clear. We sought to compare the association between maternal smoking during pregnancy and offspring ADHD with the associations with paternal smoking, grandmother's smoking when pregnant with mother, and maternal smoking in previous pregnancies...
February 2017: Pediatrics
https://www.readbyqxmd.com/read/28127411/protein-restricted-diet-during-pregnancy-after-insemination-alters-behavioral-phenotypes-of-the-progeny
#16
Tamio Furuse, Kunio Miyake, Takashi Kohda, Hideki Kaneda, Takae Hirasawa, Ikuko Yamada, Tomoko Kushida, Misho Kashimura, Kimio Kobayashi, Fumitoshi Ishino, Takeo Kubota, Shigeharu Wakana
BACKGROUND: Epidemiological studies suggest that hyponutrition during the fetal period increases the risk of mental disorders such as attention deficit hyperactivity disorder and autism-spectrum disorder, which has been experimentally supported using animal models. However, previous experimental hyponutrition or protein-restricted (PR) diets affected stages other than the fetal stage, such as formation of the egg before insemination, milk composition during lactation, and maternal nursing behavior...
2017: Genes & Nutrition
https://www.readbyqxmd.com/read/28091799/prenatal-risk-factors-and-the-etiology-of-adhd-review-of-existing-evidence
#17
REVIEW
Emma Sciberras, Melissa Mulraney, Desiree Silva, David Coghill
While it is well accepted that attention-deficit/hyperactivity disorder (ADHD) is a highly heritable disorder, not all of the risk is genetic. It is estimated that between 10 and 40% of the variance associated with ADHD is likely to be accounted for by environmental factors. There is considerable interest in the role that the prenatal environment might play in the development of ADHD with previous reviews concluding that despite demonstration of associations between prenatal risk factors (e.g. prematurity, maternal smoking during pregnancy) and ADHD, there remains insufficient evidence to support a definite causal relationship...
January 2017: Current Psychiatry Reports
https://www.readbyqxmd.com/read/28050707/effect-of-parental-obesity-and-gestational-diabetes-on-child-neuropsychological-and-behavioral-development-at-4%C3%A2-years-of-age-the-rhea-mother-child-cohort-crete-greece
#18
Vasiliki Daraki, Theano Roumeliotaki, Katerina Koutra, Vaggelis Georgiou, Mariza Kampouri, Andriani Kyriklaki, Marina Vafeiadi, Stathis Papavasiliou, Manolis Kogevinas, Leda Chatzi
Studies have suggested an association between maternal obesity pre-pregnancy and gestational diabetes (GDM) with impaired offspring neurodevelopment, but it is not clear if these associations are explained by shared familiar characteristics. We aimed to assess the associations of maternal and paternal obesity, maternal glucose intolerance in early pregnancy and GDM, with offspring neurodevelopment at 4 years of age. We included 772 mother-child pairs from the "Rhea" Mother-Child cohort in Crete, Greece. Data on maternal/paternal body mass index (BMI) and maternal fasting serum samples for glucose and insulin measurements were collected at 12 weeks of gestation...
January 3, 2017: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/27920084/caffeine-consumption-during-pregnancy-and-adhd-at-the-age-of-11%C3%A2-years-a-birth-cohort-study
#19
Bianca Del-Ponte, Iná S Santos, Luciana Tovo-Rodrigues, Luciana Anselmi, Tiago N Munhoz, Alicia Matijasevich
OBJECTIVE: Studies evaluating caffeine intake during pregnancy and long-term outcomes, such as the child's neurobehaviour, are still scarce and their results are inconsistent. The objective of the present study was to evaluate the association between maternal consumption of caffeine during pregnancy and attention deficit hyperactivity disorder (ADHD) at the age of 11 years. METHODOLOGY: All children born in the city of Pelotas, Brazil, during the year 2004, were selected for a cohort study...
December 5, 2016: BMJ Open
https://www.readbyqxmd.com/read/27907271/adult-attention-deficit-hyperactivity-disorder-diagnosis-management-and-treatment-in-the-dsm-5-era
#20
REVIEW
Joel L Young, David W Goodman
Objective: To increase awareness of adult attention-deficit/hyperactivity disorder (ADHD) in the primary care community and to provide guidance for the management of this condition. Despite its increasing prevalence, adult ADHD largely remains underdiagnosed and inappropriately treated in the United States. The publication of the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5), has provided more clear diagnostic criteria for adult ADHD, but a solid framework supporting the transition of ADHD management from pediatric to adult primary care is lacking...
November 17, 2016: Primary Care Companion to CNS Disorders
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