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Attention deficit disorder pregnancy

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https://www.readbyqxmd.com/read/29782211/attention-deficit-hyperactivity-disorder-symptoms-depression-risk-and-quality-of-life-in-black-pregnant-women
#1
Heather A Jones, Laura D Eddy, Elizaveta Bourchtein, Amanda M Parks, Tiffany L Green, Nicole W Karjane, Dace S Svikis
BACKGROUND: Experiencing mental health difficulties during pregnancy predicts a variety of quality-of-life (QoL) outcomes for Black women. However, one area of prenatal mental health remains underresearched: attention-deficit/hyperactivity disorder (ADHD). Given the impairments reported by adults with significant symptoms of ADHD and the linkages between depression and ADHD in nonpregnant samples, the current study aimed to examine the relationships among ADHD symptoms, depression, and QoL in Black pregnant women...
May 21, 2018: Journal of Women's Health
https://www.readbyqxmd.com/read/29752174/a-prospective-birth-cohort-study-on-early-childhood-lead-levels-and-attention-deficit-hyperactivity-disorder-new-insight-on-sex-differences
#2
Yuelong Ji, Xiumei Hong, Guoying Wang, Nilanjan Chatterjee, Anne W Riley, Li-Ching Lee, Pamela J Surkan, Tami R Bartell, Barry Zuckerman, Xiaobin Wang
OBJECTIVE: To investigate the prospective associations between early childhood lead exposure and subsequent risk of attention deficit hyperactivity disorder (ADHD) in childhood and its potential effect modifiers. STUDY DESIGN: We analyzed data from 1479 mother-infant pairs (299 ADHD, 1180 neurotypical) in the Boston Birth Cohort. The child's first blood lead measurement and physician-diagnosed ADHD was obtained from electronic medical records. Graphic plots and multiple logistic regression were used to examine dose-response associations between lead exposure and ADHD and potential effect modifiers, adjusting for pertinent covariables...
May 8, 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29722084/the-effects-of-maternal-risk-factors-during-pregnancy-on-the-onset-of-sleep-difficulties-in-infants-at-3-months-old
#3
Isabel Morales-Muñoz, Outi Saarenpää-Heikkilä, Anneli Kylliäinen, Pirjo Pölkki, Tarja Porkka-Heiskanen, Tiina Paunio, E Juulia Paavonen
Sleep problems in young children are among the most common concerns reported to paediatricians. Sleep is thought to have important regulatory functions, and sleep difficulties in early childhood are linked to several psychosocial and physiological problems. Moreover, several prenatal factors have been found to influence infants' sleep. Among them, most of the studies have been focused on maternal prenatal depression and/or anxiety as potential risk factors for sleep problems in childhood, whereas other relevant psychological factors during pregnancy have not received as much attention...
May 2, 2018: Journal of Sleep Research
https://www.readbyqxmd.com/read/29688261/prenatal-exposure-to-acetaminophen-and-risk-for-attention-deficit-hyperactivity-disorder-and-autistic-spectrum-disorder-a-systematic-review-meta-analysis-and-meta-regression-analysis-of-cohort-studies
#4
Reem Masarwa, Hagai Levine, Einat Gorelik, Shimon Reif, Amichai Perlman, Ilan Matok
Acetaminophen is the most commonly used analgesic and antipyretic during pregnancy. Evidence of neuro-disruptive properties is accumulating. Therefore, we sought to evaluate the risk for attention deficit hyperactivity disorder (ADHD) and autistic spectrum disorder (ASD) in the offspring of women exposed to acetaminophen during pregnancy. We searched MEDLINE, EMBASE, and Cochrane up to January 2017. Data were independently extracted and assessed by two researchers. Seven eligible retrospective cohorts included 132,738 mother and child pairs and with a follow-up period of 3-11 years...
April 24, 2018: American Journal of Epidemiology
https://www.readbyqxmd.com/read/29665879/maternal-anxiety-depression-and-sleep-disorders-before-and-during-pregnancy-and-preschool-adhd-symptoms-in-the-ninfea-birth-cohort-study
#5
L Vizzini, M Popovic, D Zugna, B Vitiello, M Trevisan, C Pizzi, F Rusconi, L Gagliardi, F Merletti, L Richiardi
AIMS: Maternal mental disorders have been associated with the risk of attention-deficit/hyperactivity disorder (ADHD) in children. Within the context of a mother-child cohort, we examined whether maternal anxiety, depression and sleep disorders are associated with pre-school ADHD symptoms. METHODS: The study included 3634 singletons from the Italian NINFEA (Nascita e INFanzia: gli Effetti dell'Ambiente') cohort. Maternal doctor-diagnosed anxiety, depression and sleep disorders before and during pregnancy were assessed from the questionnaires completed during pregnancy and 6 months after delivery...
April 18, 2018: Epidemiology and Psychiatric Sciences
https://www.readbyqxmd.com/read/29596147/maternal-antidepressant-use-during-pregnancy-and-the-risk-of-attention-deficit-hyperactivity-disorder-in-children-a-systematic-review-of-the-current-literature
#6
Faruk Uguz
PURPOSE: This study reviewed the current literature examining the potential relationship between use of antidepressants during pregnancy and attention-deficit/hyperactivity disorder (ADHD) in children. METHODS: PubMed was searched for English language reports between January 1, 1995, and July 31, 2017, by using combinations of the key words pregnancy, antidepressants, selective serotonin reuptake inhibitors (SSRIs), selective serotonin-norepinephrine reuptake inhibitors (SNRIs), tricyclic antidepressants (TCAs), children, offspring, and ADHD...
March 28, 2018: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/29588970/prevalence-risk-factors-and-neurobehavioral-comorbidities-of-epilepsy-in-kenyan-children
#7
Charles J Kind, Charles R J C Newton, Symon M Kariuki
Objective: To investigate the prevalence, risk factors, clinical features, and neurobehavioral comorbidities of epilepsy and acute symptomatic seizures in school-aged children in Kilifi, Kenya. Methods: Randomly selected children (N = 11,223) were screened for epilepsy and other neurodevelopmental disorders. Those who screened positive were invited for further clinical, electroencephalographic (EEG), and neuropsychological evaluations. Prevalence was measured by dividing cases by screened population, providing Agresti-Coull confidence intervals (CIs)...
December 2017: Epilepsia Open
https://www.readbyqxmd.com/read/29584590/maternal-thyroid-function-in-early-pregnancy-and-child-neurodevelopmental-disorders-a-danish-nationwide-case-cohort-study
#8
Stine Linding Andersen, Stig Andersen, Peter Vestergaard, Jørn Olsen
BACKGROUND: Maternal thyroid dysfunction may adversely affect fetal brain development, but more evidence is needed to refine this hypothesis. The aim of this study was to evaluate potential fetal programming by abnormal maternal thyroid function on child neurodevelopmental disorders. METHODS: The design was a case-cohort study within the Danish National Birth Cohort (1997-2003). From the eligible cohort of 71,706 women, a random 12% sub-cohort (n = 7624) was selected, and all women (n = 2276) whose child was diagnosed with seizures, specific developmental disorder (SDD), autism spectrum disorder (ASD), and/or attention-deficit/hyperactivity disorder (ADHD) up to December 31, 2010, were identified...
April 2018: Thyroid: Official Journal of the American Thyroid Association
https://www.readbyqxmd.com/read/29558816/prenatal-primary-prevention-of-mental-illness-by-micronutrient-supplements-in-pregnancy
#9
Robert Freedman, Sharon K Hunter, M Camille Hoffman
Genes, infection, malnutrition, and other factors affecting fetal brain development are a major component of risk for a child's emotional development and later mental illnesses, including schizophrenia, bipolar disorder, and autism. Prenatal interventions to ameliorate that risk have yet to be established for clinical use. A systematic review of prenatal nutrients and childhood emotional development and later mental illness was performed. Randomized trials of folic acid, phosphatidylcholine, and omega-3 fatty acid supplements assess effects of doses beyond those adequate to remedy deficiencies to promote normal fetal development despite genetic and environmental risks...
March 21, 2018: American Journal of Psychiatry
https://www.readbyqxmd.com/read/29557079/perinatal-outcomes-of-women-diagnosed-with-attention-deficit-hyperactivity-disorder-an-australian-population-based-cohort-study
#10
Alison S Poulton, Bruce Armstrong, Ralph K Nanan
BACKGROUND: Attention-deficit/hyperactivity disorder (ADHD) is common and may require treatment in adulthood. We aimed to investigate the treatment patterns and perinatal outcomes of women with any history of stimulant treatment for ADHD. METHODS: We used health records of the New South Wales (NSW, Australia) population to compare perinatal outcomes of women treated with stimulants (dexamphetamine or methylphenidate) for ADHD from 1982 to 2012 who gave birth between 1994 and 2012, with perinatal outcomes of women with no known ADHD or stimulant treatment (comparison cohort)...
March 19, 2018: CNS Drugs
https://www.readbyqxmd.com/read/29550610/pregnancy-risk-factors-in-relation-to-oppositional-defiant-and-conduct-disorder-symptoms-in-the-avon-longitudinal-study-of-parents-and-children
#11
I Hyun Ruisch, Jan K Buitelaar, Jeffrey C Glennon, Pieter J Hoekstra, Andrea Dietrich
BACKGROUND: Pregnancy factors have been implicated in offspring oppositional-defiant disorder (ODD) and conduct disorder (CD) symptoms. Literature still holds notable limitations, such as studying only a restricted set of pregnancy factors, use of screening questionnaires which assess broadly defined outcome measures, and lack of control for disruptive behavior comorbidity and genetic confounds. We aimed to address these gaps by prospectively studying a broad range of pregnancy factors in relation to both offspring ODD and CD symptomatology in the Avon Longitudinal Study of Parent and Children...
February 23, 2018: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/29505179/adverse-gestational-outcomes-associated-with-attention-deficit-hyperactivity-disorder-medication-exposure-during-pregnancy
#12
Chittaranjan Andrade
The use of attention-deficit/hyperactivity disorder (ADHD) medications during pregnancy has increased in recent years. An earlier article in this column examined whether psychostimulant medications, used to treated ADHD and related disorders, increase the risk of major congenital malformations in pregnancies with first trimester exposure to these drugs. This article examines whether amphetamines, methylphenidate, and atomoxetine exposure during early and late pregnancy are associated with other adverse gestational outcomes...
January 2018: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/29485905/infant-exposure-to-methylphenidate-and-duloxetine-during-lactation
#13
Laurence Collin-Lévesque, Yosra El-Ghaddaf, Madeleine Genest, Martin Jutras, Grégoire Leclair, Etienne Weisskopf, Alice Panchaud, Ema Ferreira
BACKGROUND: Duloxetine and methylphenidate are commonly prescribed for the management of depression and attention-deficit/hyperactivity disorder (ADHD), respectively. However, little information is available concerning their safety during lactation. The purpose of this case series was to provide additional information to the medical literature concerning infant exposure to methylphenidate and duloxetine through breast milk. METHOD: Bioanalytical method (liquid chromatography coupled to mass spectrometry) was developed and validated before its use to determine the concentrations of both medications in breast milk samples...
April 2018: Breastfeeding Medicine: the Official Journal of the Academy of Breastfeeding Medicine
https://www.readbyqxmd.com/read/29411149/pharmacological-treatment-of-attention-deficit-hyperactivity-disorder-during-pregnancy-and-lactation
#14
REVIEW
Asher Ornoy
INTRODUCTION: Attention deficit/hyperactivity disorder (ADHD) is a neurobehavioral problem found in 2-5% of adults. Stimulants and drugs that affect the dopaminergic, noradrenergic and/or serotonergic systems are effective treatment and are increasingly prescribed to women at child bearing age. It is consequently important that reliable information on the safety of these drugs in pregnancy is available so that appropriate therapeutic choices can be made. RESULTS: The data on stimulants (methylphenidate and amphetamines) are generally showing that there is no increase in the rate of major congenital anomalies...
February 6, 2018: Pharmaceutical Research
https://www.readbyqxmd.com/read/29364128/investigating-the-effect-of-perinatal-nicotine-exposure-on-dopaminergic-neurons-in-the-vta-using-mirna-expression-profiles
#15
Renee F Keller, Pinar Kanlikilicer, Andrei Dragomir, Yantao Fan, Yasemin M Akay, Metin Akay
Maternal smoking during pregnancy is associated with developmental, cognitive, and behavioral disorders, including low birth weight, attention deficit hyperactivity disorder, learning disabilities, and drug abuse later in life. Nicotine activates the reward-driven behavior characteristic of drug abuse. Dopaminergic (DA) neurons originating from the ventral tegmental area (VTA) of the brain, which are stimulated by nicotine and other stimuli, are widely implicated in the natural reward pathway that is known to contribute to addiction...
December 2017: IEEE Transactions on Nanobioscience
https://www.readbyqxmd.com/read/29346342/attention-deficit-hyperactivity-disorder-medication-prescription-claims-among-privately-insured-women-aged-15-44-years-united-states-2003-2015
#16
Kayla N Anderson, Elizabeth C Ailes, Melissa Danielson, Jennifer N Lind, Sherry L Farr, Cheryl S Broussard, Sarah C Tinker
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder that affects individuals across the lifespan. ADHD medication use among pregnant women is increasing (1), but consensus about the safety of ADHD medication use during pregnancy is lacking. Given that nearly half of U.S. pregnancies are unintended (2), and early pregnancy is a critical period for fetal development, examining trends in ADHD medication prescriptions among reproductive-aged women is important to quantify the population at risk for potential exposure...
January 19, 2018: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/29341895/prenatal-paracetamol-exposure-and-child-neurodevelopment-a-review
#17
REVIEW
Ann Z Bauer, David Kriebel, Martha R Herbert, Carl-Gustaf Bornehag, Shanna H Swan
BACKGROUND: The non-prescription medication paracetamol (acetaminophen, APAP) is currently recommended as a safe pain and fever treatment during pregnancy. However, recent studies suggest a possible association between APAP use in pregnancy and offspring neurodevelopment. OBJECTIVES: To conduct a review of publications reporting associations between prenatal APAP use and offspring neurodevelopmental outcomes. METHODS: Relevant sources were identified through a key word search of multiple databases (Medline, CINAHL, OVID and TOXNET) in September 2016...
February 2, 2018: Hormones and Behavior
https://www.readbyqxmd.com/read/29340801/maternal-depression-trajectories-from-pregnancy-to-3-years-postpartum-are-associated-with-children-s-behavior-and-executive-functions-at-3-and-6-years
#18
Mina Park, Ursula Brain, Ruth E Grunau, Adele Diamond, Tim F Oberlander
The objective of this study was to investigate how patterns of maternal depressive symptoms from mid-pregnancy to 3 years postpartum are associated with children's behavior at age 3 years and executive functions. Maternal depressive symptoms were measured from mid-pregnancy to 3 years postpartum. Growth mixture modeling was used on standardized maternal depression scores (n = 147) to identify trajectories. Children's behavioral problems and mental health symptomatology (internalizing, externalizing, and attention deficit hyperactivity disorder) were obtained at 3 and 6 years...
January 16, 2018: Archives of Women's Mental Health
https://www.readbyqxmd.com/read/29332605/antidepressant-use-during-pregnancy-and-risk-of-autism-spectrum-disorder-and-attention-deficit-hyperactivity-disorder-systematic-review-of-observational-studies-and-methodological-considerations
#19
Daniel R Morales, Jim Slattery, Stephen Evans, Xavier Kurz
BACKGROUND: Antidepressant exposure during pregnancy has been associated with an increased risk of autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD) in several observational studies. We performed a systematic review of these studies to highlight the effect that important methodological limitations have on such analyses and to consider approaches to the conduct, reporting and interpretation of future studies. METHODS: A review of MEDLINE and EMBASE identified case-control, cohort and sibling studies assessing the risk of ASD and ADHD with antidepressant use during pregnancy...
January 15, 2018: BMC Medicine
https://www.readbyqxmd.com/read/29325223/maternal-thyroid-hormone-insufficiency-during-pregnancy-and-risk-of-neurodevelopmental-disorders-in-offspring-a-systematic-review-and-meta-analysis
#20
William Thompson, Ginny Russell, Genevieve Baragwanath, Justin Matthews, Bijay Vaidya, Jo Thompson-Coon
BACKGROUND: In the last 2 decades, several studies have examined the association between maternal thyroid hormone insufficiency during pregnancy and neurodevelopmental disorders in children and shown conflicting results. AIM: This systematic review aimed to assess the evidence for an association between maternal thyroid hormone insufficiency during pregnancy and neurodevelopmental disorders in children. We also sought to assess whether levothyroxine treatment for maternal thyroid hormone insufficiency improves child neurodevelopment outcomes...
April 2018: Clinical Endocrinology
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