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https://www.readbyqxmd.com/read/27891706/rectal-intussusception-can-high-resolution-three-dimensional-ano-rectal-manometry-compete-with-conventional-defecography
#1
A Benezech, M Cappiello, K Baumstarck, J-C Grimaud, M Bouvier, V Vitton
BACKGROUND: Three-dimensional high-resolution anorectal manometry (3DHRAM), used for exploring anorectal disorders, was recently developed, providing interesting topographic data for the diagnosis of pelvic floor disorders such as excessive perineal descent. The aim of our study was to define a diagnostic strategy based on selected 3DHRAM parameters to identify rectal intussusceptions (RI), considering conventional defecography (CD) as the gold standard. METHODS: All patients referred to our center in the previous 6 months for 3DHRAM to explore fecal incontinence or constipation, and who previously achieved CD, were eligible...
November 27, 2016: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/27857005/polypoid-anal-melanoma-a-case-report-and-review-of-the-literature
#2
Roberta Tutino, Giuseppe Clerico, Alberto Realis Luc, Gaetano Gallo, Mario Trompetto
INTRODUCTION: Ano-rectal melanoma is an uncommon finding in patients complaining of rectal bleeding and/or anal mass often misinterpreted as a haemorroidal pile. CASE REPORT: A 55-years-old woman, complaining of rectal bleeding, frequent anal pain and anal mass suspected for haemorroidal thrombosis was referred for evaluation and possible treatment. A brown polypoid mass arising from the anal canal/lower rectum with a maximum diameter of 6 cm was diagnosed. The hystological examination of the neoplasm, transanally removed, revealed the presence of a polypoid melanoma partially involving the resection margin...
November 12, 2016: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/27527239/outcomes-after-acute-traumatic-spinal-cord-injury-in-botswana-from-admission-to-discharge
#3
I Löfvenmark, M Hasselberg, L Nilsson Wikmar, C Hultling, C Norrbrink
STUDY DESIGN: Prospective follow-up study. OBJECTIVES: To increase the knowledge regarding clinical and functional outcomes after traumatic spinal cord injuries (TSCI) in a resource-constrained setting. A special focus was placed on secondary complications such as pressure ulcers. SETTING: The national referral hospital in Gaborone, Botswana. METHODS: The study included all patients admitted with an acute TSCI during a 2-year period (n=39)...
August 16, 2016: Spinal Cord
https://www.readbyqxmd.com/read/27502879/clinical-spectrum-of-neonates-presenting-with-pneumoperitoneum-a-retrospective-study
#4
Ahmed Hosni Morsi, Hossam Rashad Omar, Ahmed Osama, Ahmed Refaat Khodary
BACKGROUND: Neonatal pneumoperitoneum is attributed, in most of the reported cases, to necrotising enterocolitis (NEC). There are also other causes leading to free intraperitoneal air. The aim of this study is to describe the clinical spectrum, causes, management and outcome of neonates admitted with pneumoperitoneum in the paediatric surgery unit of a university hospital. SUBJECTS AND METHODS: This retrospective study included neonates having radiographic evidences of pneumoperitoneum from 2012 to the end of 2014...
July 2016: African Journal of Paediatric Surgery: AJPS
https://www.readbyqxmd.com/read/27426509/curative-effect-of-amorphophallus-paeoniifolius-tuber-on-experimental-hemorrhoids-in-rats
#5
Yadu Nandan Dey, Manish M Wanjari, Dharmendra Kumar, Vinay Lomash, Ankush D Jadhav
ETHNOPHARMACOLOGICAL RELEVANCE: Amorphophallus paeoniifolius (Dennst.) Nicolson (Family- Araceae) is a crop of south East Asian origin. In India, its tuber is widely used in ethnomedicinal practices by different tribes for the treatment of piles (hemorrhoid). AIM: The present study evaluated the effect of methanolic and aqueous extract of Amorphophallus paeoniifolius tuber on croton oil induced hemorrhoids in rats. MATERIALS AND METHODS: The methanolic extract was standardized with the major phenolic compound, betulinic acid, by HPLC...
July 14, 2016: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27363649/low-vertebral-ano-rectal-cardiac-tracheo-esophageal-renal-limb-screening-rates-in-children-with-anorectal-malformations
#6
Victoria A Lane, Erica Ambeba, Deena J Chisolm, Daniel Lodwick, Marc A Levitt, Richard J Wood, Katherine J Deans, Peter C Minneci
BACKGROUND: The aim of this study was to establish the rate of screening for associated cardiac, vertebral, spinal cord, urologic, and limb anomalies vertebral ano-rectal cardiac tracheo-esophageal renal limb (VACTERL) in children with anorectal malformation (ARM). METHODS: We performed a retrospective cohort study using the Medicaid Analytic eXtract database which contains enrollment and utilization claims and demographic information from all Medicaid enrollees...
June 15, 2016: Journal of Surgical Research
https://www.readbyqxmd.com/read/27272772/imaging-of-gastrointestinal-stromal-tumors-from-diagnosis-to-evaluation-of-therapeutic-response
#7
REVIEW
Federica Vernuccio, Adele Taibbi, Dario Picone, Ludovico LA Grutta, Massimo Midiri, Roberto Lagalla, Giuseppe Lo Re, Tommaso Vincenzo Bartolotta
Once considered an obscure tumor entity with poor prognosis, gastrointestinal stromal tumors (GISTs) are nowadays recognized as the most common mesenchymal tumors of the alimentary tract. GISTs differ from other mesenchymal neoplasms at pathology since 90% of them exhibit strong immunohistochemical staining for KIT, a tyrosinase kinase growth factor receptor. In the early 2000s, the ability of imatinib mesylate, a tyrosine kinase inhibitor, to inhibit KIT established a new paradigm for cancer treatment. A reduction in lesion size may not be observed or may appear many months after therapy; thus, tumor response criteria alternative to the Response Evaluation Criteria in Solid Tumors were developed...
June 2016: Anticancer Research
https://www.readbyqxmd.com/read/27272501/do-pelvic-floor-muscle-exercises-reduce-postpartum-anal-incontinence-a-randomised-controlled-trial
#8
H H Johannessen, A Wibe, A Stordahl, L Sandvik, S Mørkved
OBJECTIVE: To evaluate the effect of pelvic floor muscle exercises (PFME) for postpartum anal incontinence (AI). DESIGN: A parallel two-armed randomised controlled trial stratified on obstetrical anal sphincter injury with primary sphincter repair and hospital affinity. SETTING: Ano-rectal specialist out-patient clinics at two hospitals in Norway. POPULATION: One hundred and nine postpartum women with AI at baseline...
June 7, 2016: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/27178068/anorectal-pathology-amongst-hiv-infected-patients-attending-the-douala-general-hospital-a-cross-sectional-study
#9
Henry Namme Luma, Servais Albert Fiacre Bagnaka Eloumou, Ellis Atemlefeh Fualefeh-Morfaw, Agnes Malongue, Elvis Temfack, Fernando Kemta Lekpa, Olivier Donfack-Sontsa, Lucy Ndip, Ivo Che Ditah
While gastrointestinal disease is common among HIV infected individuals, the prevalence and distribution of ano-rectal pathology has not been well studied in our setting. The objective of this study therefore was to determine the prevalence and determinants of ano-rectal pathology in HIV infected patients attending the Douala General Hospital HIV treatment centre. A hospital-based cross-sectional study was undertaken. We collected socio-demographic, clinical and laboratory data using a structured questionnaire and patients' files...
May 12, 2016: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/27142439/single-port-endoscopic-mesocolic-and-mesorectal-excision-using-an-extraperitoneal-approach
#10
F Dumont, E Thibaudeau, L Benhaïm, S Gouy, D Labbe, C Honoré, D Goéré
BACKGROUND: The extraperitoneal rectal dissection via a transanal approach facilitates the mesorectal dissection. The retroperitoneal approach for mesocolic excision may also offer some similar advantages. To complete the lymphadenectomy of extraperitoneal mesorectal resection, we developed an innovative approach for upper rectal and mesocolic excision via an exclusive retroperitoneal dissection using a single-port access at the site of the future stomy. METHODS: This study was a prospective pilot study and was conducted between 2013 and 2015 at two oncologic centers...
May 3, 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/27055486/adaptive-radiotherapy-strategies-for-pelvic-tumors-a-systematic-review-of-clinical-implementations
#11
Sara Thörnqvist, Liv B Hysing, Laura Tuomikoski, Anne Vestergaard, Kari Tanderup, Ludvig P Muren, Ben J M Heijmen
UNLABELLED: Introdution: Variation in shape, position and treatment response of both tumor and organs at risk are major challenges for accurate dose delivery in radiotherapy. Adaptive radiotherapy (ART) has been proposed to customize the treatment to these motion/response patterns of the individual patients, but increases workload and thereby challenges clinical implementation. This paper reviews strategies and workflows for clinical and in silico implemented ART for prostate, bladder, gynecological (gyne) and ano-rectal cancers...
August 2016: Acta Oncologica
https://www.readbyqxmd.com/read/26942721/cost-effectiveness-of-screening-for-anal-cancer-using-regular-digital-ano-rectal-examinations-in-men-who-have-sex-with-men-living-with-hiv
#12
Jason J Ong, Christopher K Fairley, Susan Carroll, Sandra Walker, Marcus Chen, Tim Read, Andrew Grulich, Catriona Bradshaw, John Kaldor, Philip Clarke
INTRODUCTION: Anal cancer in men who have sex with men (MSM) living with HIV is an important issue but there are no consistent guidelines for how to screen for this cancer. In settings where screening with anal cytology is unavailable, regular anal examinations have been proposed in some guidelines but their cost-effectiveness is unknown. METHODS: Our objective was to estimate the cost-effectiveness of regular anal examinations to screen for anal cancer in HIV-positive MSM living in Australia using a probabilistic Markov model...
2016: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/26898491/rectal-manometric-findings-and-associated-clinical-changes-in-myelopathy-from-extradural-spine-pathology
#13
Anant Mehrotra, Janmejay Jamdar, Abhai Verma, Kuntal Kanti Das, Kamlesh Singh Bhaisora, Jayesh Chunnilal Sardhara, Jaskaran Singh Gosal, Awadhesh Kumar Jaiswal, Rabi Narayan Sahu, Arun Kumar Srivastava, Sanjay Behari
OBJECTIVE: Studies of rectal manometric findings in patients with extradural spine diseases are lacking. The objective of this study was to determine the changes in anorectal physiology caused by myelopathy from extradural spine diseases and to correlate these with other clinical features of myelopathy and improvement after surgery. METHODS: Twenty-eight patients with myelopathy caused by extradural spine diseases were prospectively enrolled and underwent clinical evaluation...
June 2016: World Neurosurgery
https://www.readbyqxmd.com/read/26642347/validity-of-estimation-of-pelvic-floor-muscle-activity-from-transperineal-ultrasound-imaging-in-men
#14
Ryan E Stafford, Geoff Coughlin, Nicholas J Lutton, Paul W Hodges
PURPOSE: To investigate the relationship between displacement of pelvic floor landmarks observed with transperineal ultrasound imaging and electromyography of the muscles hypothesised to cause the displacements. MATERIALS AND METHODS: Three healthy men participated in this study, which included ultrasound imaging of the mid-urethra, urethra-vesical junction, ano-rectal junction and bulb of the penis. Fine-wire electromyography electrodes were inserted into the puborectalis and bulbocavernosus muscles and a transurethral catheter electrode recorded striated urethral sphincter electromyography...
2015: PloS One
https://www.readbyqxmd.com/read/26612122/laparoscopic-assisted-vaginal-pull-through-a-new-approach-for-congenital-adrenal-hyperplasia-patients-with-high-urogenital-sinus
#15
Jacques Birraux, Faustin Tambo Mouafo, Sophie Dahoun, Veronique Tardy, Yves Morel, Pierre Mouriquand, Claude Le Coultre, Pierre-Yves Mure
BACKGROUND: To open vaginal cavity to the pelvic floor is part of surgical treatment for urogenital sinus (UGS) in girls with congenital adrenal hyperplasia (CAH). For high UGS, this operative procedure can be challenging and may jeopardise urinary continence. Combined perineal and laparoscopic approaches could be useful to minimise perineal dissection and to facilitate the vaginal lowering. PATIENTS AND METHODS: We report the procedure of a laparoscopic-assisted vaginal pull-through for supra-sphincteric UGS in a 5-year-old girl with CAH...
July 2015: African Journal of Paediatric Surgery: AJPS
https://www.readbyqxmd.com/read/26603727/pelvic-floor-dysfunction-in-inflammatory-bowel-disease
#16
A Bondurri, A Maffioli, P Danelli
Advances in tailored medical therapy and introduction of biologic agents for inflammatory bowel disease (IBD) treatment have ensured long-term disease remission. Some patients, however, still report defecatory symptoms. Patients present with a wide spectrum of conditions - anal incontinence, obstructed defecation and pelvic pain among the most frequent - that have a great impact on their quality of life. Due to IBD diagnosis, little relevance is attributed to this type of symptoms and their epidemiologic distribution is unknown...
December 2015: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/26550808/-local-and-late-complications-in-anorectal-surgery
#17
F Gaj, L Candeloro, I Biviano
BACKGROUND AND AIMS: Our experience in colon-proctology showed the need to update the post-surgical complications score we published (1), adding others that may have an impact on outcome of treatment. The aim of this study was to assess the efficacy of a score obtained from the analysis of the quality of life and severity of complications after proctologic surgery. MATERIALS AND METHODS: Between January and December 2013, we studied 150 patients undergoing several ano-rectal surgeries for the presence of hemorrhoids of grade III and IV (63 patients), anal fissures (42 patients), anal fistulas (19 patients), rectocele (15 patients) and mucosal prolapse of the rectum (11 patients)...
2015: La Clinica Terapeutica
https://www.readbyqxmd.com/read/26545803/gastrointestinal-features-of-chronic-granulomatous-disease-found-during-endoscopy
#18
Sajneet K Khangura, Natasha Kamal, Nancy Ho, Martha Quezado, Xiongce Zhao, Beatriz Marciano, Jennifer Simpson, Christa Zerbe, Gulbu Uzel, Michael D Yao, Suk See DeRavin, Colleen Hadigan, Douglas B Kuhns, John I Gallin, Harry L Malech, Steven M Holland, Theo Heller
BACKGROUND & AIMS: Chronic granulomatous disease (CGD) is an inherited disorder of the reduced nicotinamide adenine dinucleotide phosphate oxidase complex within phagocytic cells that predisposes people to bacterial and fungal infections. Approximately 40% of patients with CGD have gastrointestinal involvement. We aimed to characterize the endoscopic features of gastrointestinal CGD and define the role of endoscopy in patients. METHODS: We created a database of all patients with CGD seen at the National Institutes of Health from 1990 through 2010...
March 2016: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/26462726/baseline-findings-from-the-anal-cancer-examination-ace-study-screening-using-digital-ano-rectal-examination-in-hiv-positive-men-who-have-sex-with-men
#19
Jason J Ong, Andrew Grulich, Sandra Walker, Jennifer Hoy, Tim Read, Catriona Bradshaw, Suzanne M Garland, Richard Hillman, David Templeton, Jane Hocking, Beng Eu, B K Tee, Christopher K Fairley
OBJECTIVE: Cytological screening for anal cancer precursors is not always possible. We investigated digital ano-rectal examination (DARE) as a means of early anal cancer detection in HIV-positive men who have sex with men (MSM). METHODS: We recruited 327 HIV-positive MSM aged 35 and over from clinics with HIV physicians in Melbourne, Australia, to receive an annual DARE. We analyzed baseline data from patient questionnaires regarding general, anal and sexual health, adverse effects from the anal examination, cancer worry, and quality of life...
June 2016: Journal of Medical Screening
https://www.readbyqxmd.com/read/26418472/straddle-injury-with-anal-sphincter-and-rectal-rupture-in-a-young-girl-case-report
#20
Renato Pietroletti, Federica Delreno, Amalia D'Orsi, Stefano Caoci, Francesco Carlei
UNLABELLED: As a result of increasing sport or car accident, straddle injuries in pediatric age are becoming increasingly frequent. Mild lesions of the external genitalia and urinary apparatus, are mainly observed in blunt trauma, whereas more severe lesions are reported in penetrating injuries; however, ano-rectal involvement alone, has been reported very rarely and especially in penetrating trauma. We describe herein a case of straddle trauma occurring in a 14yr old girl involved in a car accident...
2015: Annali Italiani di Chirurgia
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