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https://www.readbyqxmd.com/read/27914138/therapeutic-response-for-functional-abdominal-pain-in-children-with-occult-constipation-laxatives-versus-prokinetic-drugs
#1
Eun Kyo Ha, Homin Jang, Su Jin Jeong
The relationship between functional abdominal pain (FAP) and occult constipation (OC) in children who did not meet the Rome III criteria for constipation has rarely been reported. This study aimed to estimate the prevalence of OC in patients with FAP and to compare the effectiveness of prokinetic drugs and laxatives for FAP and OC. Pediatric outpatients (n = 212; aged 4-15 years) who satisfied the Rome III criteria for childhood FAP were divided into 2 groups based on Leech scores: group 1 < 8; group 2 ≥ 8...
January 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/27905265/learning-together-part-2-training-costs-and-health-gain-a-cost-analysis
#2
Katherine Cullen, Wendy Riches, Chloe Macaulay, John Spicer
: Learning Together is a complex educational intervention aimed at improving health outcomes for children and young people. There is an additional cost as two doctors are seeing patients together for a longer appointment than a standard general practice (GP) appointment. Our approach combines the impact of the training clinics on activity in South London in 2014-15 with health gain, using NICE guidance and standards to allow comparison of training options. METHODS: Activity data was collected from Training Practices hosting Learning Together...
December 1, 2016: Education for Primary Care
https://www.readbyqxmd.com/read/27899001/drug-interventions-for-the-treatment-of-obesity-in-children-and-adolescents
#3
REVIEW
Emma Mead, Greg Atkinson, Bernd Richter, Maria-Inti Metzendorf, Louise Baur, Nicholas Finer, Eva Corpeleijn, Claire O'Malley, Louisa J Ells
BACKGROUND: Child and adolescent obesity has increased globally, and can be associated with significant short- and long-term health consequences. OBJECTIVES: To assess the efficacy of drug interventions for the treatment of obesity in children and adolescents. SEARCH METHODS: We searched CENTRAL, MEDLINE, Embase, PubMed (subsets not available on Ovid), LILACS as well as the trial registers ICTRP (WHO) and ClinicalTrials.gov. Searches were undertaken from inception to March 2016...
November 29, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27896373/assessing-colonic-anatomy-normal-values-based-on-air-contrast-enemas-in-children-younger-than-6%C3%A2-years
#4
Ilan J N Koppen, Desale Yacob, Carlo Di Lorenzo, Miguel Saps, Marc A Benninga, Jennifer N Cooper, Peter C Minneci, Katherine J Deans, D Gregory Bates, Benjamin P Thompson
BACKGROUND: Contrast enemas with barium or water-soluble contrast agents are sometimes performed in children with severe intractable constipation to identify anatomical abnormalities. However there are no clear definitions for normal colonic size or abnormalities such as colonic dilation or sigmoid redundancy in children. OBJECTIVE: To describe characteristics of colonic anatomy on air contrast enemas in children without constipation to provide normal values for colonic size ratios in children...
November 29, 2016: Pediatric Radiology
https://www.readbyqxmd.com/read/27892845/learning-together-1-an-educational-model-for-training-gps-paediatricians-initial-findings
#5
Chloe Macaulay, John Spicer, Wendy Riches, Monica Lakhanpaul
Learning Together is primarily an educational intervention, where paediatric registrars [SpRs] and General Practice (GP) registrars [GPSTs] see children together in a primary care setting. Over a six month period in 2013/2014, 44 learning pairs were set up mainly in North East and Central London. Proof of concept for the model at scale was achieved. Reported learning demonstrated: clinical learning themes of new knowledge, skill and communication skills; and collaborative themes of ongoing collaboration, satisfaction with team working and change in attitudes...
November 28, 2016: Education for Primary Care
https://www.readbyqxmd.com/read/27891287/sapovirus-gastroenteritis-in-young-children-presenting-as-distal-small-bowel-obstruction-a-report-of-2-cases-and-literature-review
#6
Lynn Model, Cathy Anne Burnweit
Abdominal pain and distention in children are commonly encountered problems in the pediatric emergency room. The majority of complaints are found to be due to benign entities such as gastroenteritis and constipation. What confounds these diagnoses is that young children often deliver a challenging and unreliable exam. Thus, it often becomes exceedingly problematic to differentiate these benign conditions from surgical conditions requiring prompt attention including small or large bowel obstruction, volvulus, and appendicitis...
2016: Case Reports in Surgery
https://www.readbyqxmd.com/read/27891230/development-of-a-population-pharmacokinetic-model-of-prucalopride-in-children-with-functional-constipation
#7
Erno van Schaick, Marc A Benninga, Amy Levine, Mats Magnusson, Steven Troy
A recent phase 3 trial of prucalopride in children with functional constipation (SPD555-303 ClinicalTrials.gov Identifier: NCT01330381) reported negative efficacy results. Here, we developed a population pharmacokinetic (PK) model of prucalopride in children to assess prucalopride exposure in SPD555-303. An initial population PK model in children was developed based on sampled single-dose data from a phase 1 study (PRU-USA-12). This model was subsequently updated with sampled data from SPD555-303 and used to simulate plasma concentration-time profiles for children aged 6 months to 18 years who were treated once daily with prucalopride 0...
August 2016: Pharmacology Research & Perspectives
https://www.readbyqxmd.com/read/27890312/variables-associated-with-loss-of-ileoanal-pouches-constructed-in-childhood
#8
Khaled Abdelaal, Bruce Jaffray
AIMS: To quantify the incidence of loss of an ileoanal pouch in children and to identify variables associated this event. METHODS: Logistic regression of possible explanatory variables: age, sex, indication for procto-colectomy, pre-operative continence status, use of immunosuppressive drugs, open or laparoscopic surgery, number of stages, anastomotic leak, operative complication excluding anastomotic leak, performance of revisional surgery, albumin concentration and platelet count at time of surgery, rank order in series...
November 13, 2016: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/27887934/currarino-syndrome-in-a-fetus-infant-child-and-adolescent-spectrum%C3%A2-of-clinical-presentations-and-imaging-findings
#9
REVIEW
Pablo Caro-Domínguez, Juan Bass, Julie Hurteau-Miller
In 1981, Currarino et al described a triad of findings that consist of partial sacral dysgenesis, presacral mass (anterior meningocele, enteric cyst, or presacral teratoma) and anorectal malformation. Currarino syndrome exhibits variable expressivity and the clinical presentation tends to vary with the age of the subject such as spinal anomaly detected in the fetus, imperforate anus in the newborn, and intractable constipation or neurologic symptoms in the infant and older child. At any age, meningitis can be the presenting symptom and imaging is required for proper investigation...
November 22, 2016: Canadian Association of Radiologists Journal, Journal L'Association Canadienne des Radiologistes
https://www.readbyqxmd.com/read/27887683/sacral-nerve-stimulation-allows-for-decreased-antegrade-continence-enema-use-in-children-with-severe-constipation
#10
Peter L Lu, Lindsey Asti, Daniel L Lodwick, Kristine M Nacion, Katherine J Deans, Peter C Minneci, Steven Teich, Seth A Alpert, Desale Yacob, Carlo Di Lorenzo, Hayat M Mousa
BACKGROUND: Sacral nerve stimulation (SNS) can be beneficial for children with constipation, but no studies have focused on children with constipation severe enough to require antegrade continence enemas (ACEs). Our objective was to evaluate the efficacy of SNS in children with constipation treated with ACE. METHODS: Using a prospective patient registry, we identified patients <21years old who were receiving ACE prior to SNS placement. We compared ACE/laxative usage, PedsQL Gastrointestinal Symptom Scale (GSS), Fecal Incontinence Quality of Life Scale (FIQL), Fecal Incontinence Severity Index (FISI), and Vancouver Dysfunctional Elimination Syndrome Score (DES) at baseline and progressive follow-up time intervals...
November 10, 2016: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/27878110/discontinuation-of-antimicrobial-prophylaxis-ap-in-children-with-spina-bifida-a-case-series-analysis
#11
Kevin G Couloures, Michael Anderson, Michael Machiorlatti, Olivera Marsenic, Lawrence Opas
BACKGROUND: Spina bifida increases the risk for urinary tract infections (UTI). Antimicrobial prophylaxis (AP) reduces symptomatic UTI's but selects resistant organisms. Measures to ensure regular and complete emptying of the bladder combined with treatment of constipation reduce the risk for UTI. OBJECTIVES: Demonstrate that close adherence to a catheterization regimen in children with spina bifida (Selective Treatment - ST) reduces the need for antimicrobial prophylaxis...
September 2016: Nephro-urology Monthly
https://www.readbyqxmd.com/read/27875021/lifestyle-and-bowel-movements-in-school-children-results-from-the-toyama-birth-cohort-study
#12
Masaaki Yamada, Michikazu Sekine, Takashi Tatsuse
BACKGROUND: Constipation is prevalent health disorder and it has been bothering many pediatricians as well as people suffering from constipation. There have been few epidemiological surveys about constipation in Japanese children. This study aims to evaluate the prevalence of non-daily bowel movements (BM) and irregular BM among children and to identify modifiable lifestyle factors relevant to their bowel habits. METHODS: Subjects were from the Toyama Birth Cohort Study in Japan...
November 22, 2016: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/27870784/intussusception-with-cecal-cyst-as-lead-point-in-a-child
#13
Michelle Lai, Brian A Coakley, Eric M Webber, Ran D Goldman
Intussusception is a pediatric abdominal emergency in early childhood involving telescoping of 1 part of the bowel into another part. In most children, the condition is idiopathic with no identifiable lead point. Meckel diverticulum is the most common lead point, followed by polyps and duplication cysts. We describe a case of a boy with intussusception caused by a duplication cyst that was drawn retrograde through the ileocecal valve. The patient presented after a 3-month period of symptomatology and had been considered to have constipation before signs of intestinal obstruction developed...
November 19, 2016: Pediatric Emergency Care
https://www.readbyqxmd.com/read/27862592/retrograde-continence-enema-in-children-with-spina-bifida-not-as-effective-as-first-thought
#14
Sebastian K King, Lefteris Stathopoulos, Loreto Pinnuck, Judy Wells, John Hutson, Yves Heloury
AIM: The aim of the study is to investigate the effectiveness of Peristeen retrograde continence enema (RCE) in the management of faecal incontinence in children with spina bifida. METHODS: We identified a homogenous group of spina bifida patients in whom RCE was initiated (Jan 2006-July 2013). Confidential assessments included (i) Fecal Incontinence Quality Of Life (FIQOL), (ii) St Marks Faecal Incontinence score, (iii) Cleveland Clinic Constipation score and (iv) Neurogenic Bowel Dysfunction score...
November 10, 2016: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/27858582/long-term-outcome-of-laparoscopic-duhamel-procedure-for-extended-hirschsprung-s-disease
#15
Cécile O Muller, Guillaume Rossignol, Louise Montalva, Jerome Viala, Christine Martinez-Vinson, Alexis Mosca, Dominique Berrebi, Arnaud Bonnard
BACKGROUND: The aim of our study was to report our experience in extended Hirschsprung's disease (HD) in children operated on by laparoscopy. PATIENTS AND METHODS: Retrospective data collection from a single center from 1991 to 2013 concerned extended forms of HD operated on by laparoscopic Duhamel procedure and included extension of aganglionosis, comorbidities, short and late postoperative outcome, and results of endoscopy when performed. RESULTS: Thirty patients presented an extended form of aganglionosis: 5 involving the transverse colon, 10 the right colon, and 15 the ileum (median length = 15 cm, range 1-60)...
November 18, 2016: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/27857647/nutrition-chez-le-br%C3%A3-l%C3%A3
#16
G Perro
Nutrition is a challenge for burn patients. Emphasized points are early enteral amounts by means of a naso-gastric tube, semi-recumbent position > 30°, gastro-intestinal survey improved by kinetics, weight evolution, nutritional amounts assessment to prevent proteino-energetic deficiency. Feeding is difficult with children, as with seniors often associating a preexisting starvation. Nutritional supplements are useful in medium severity patients. For overweight patients, hypo caloric and hyperprotidic diet is the better choice...
March 31, 2016: Annals of Burns and Fire Disasters
https://www.readbyqxmd.com/read/27854194/prevention-and-treatment-of-constipation-in-children-from-the-perspective-of-iranian-traditional-medicine
#17
REVIEW
Monireh Sadat Motaharifard, Zahra Jafari, Maryam Sadat Paknejad, Laleh Oveidzadeh, Mehrdad Karimi
Constipation is one of the most common complaints of children and a common cause of referrals to pediatricians. Numerous reasons for this disease have been mentioned in the Iranian traditional medicine (ITM). It is believed that this disorder is mostly due to the lack of consideration of the six essential principles (Setteh-ye-Zarurieah), which are necessary to maintain health and prevent disease. In this descriptive study we collected and classified the concepts related to the topic by reviewing reliable ITM text books...
November 2016: Journal of Integrative Medicine
https://www.readbyqxmd.com/read/27849232/long-term-evaluation-of-fecal-continence-and-quality-of-life-in-patients-operated-for-anorectal-malformations
#18
Ana Cristina Aoun Tannuri, Mariana Aparecida Elisei Ferreira, Arthur Loguetti Mathias, Uenis Tannuri
Introduction: Patients operated for correction of anorectal malformations (ARM) can develop fecal incontinence, constipation, and soiling, with loss in quality of life. Objective: To evaluate, through the use of questionnaires, fecal continence, and quality of life of children in the late postoperative follow-up of ARM correction, both high and low. In addition, the levels of fecal continence and quality of life were compared with those of a control group. Method: A Fecal Continence Index Questionnaire (ICF) and a Questionnaire for Assessment of Quality of Life Related to Fecal Continence in Children and Adolescents (QQVCFCA) were administered to 63 patients with ARM, aged from 7 to 19 years, whose surgical treatment had been completed for at least 6 months...
September 2016: Revista da Associação Médica Brasileira
https://www.readbyqxmd.com/read/27836356/effectiveness-of-senna-vs-polyethylene-glycol-as-laxative-therapy-in-children-with-constipation-related-to-anorectal-malformation
#19
Karla Alejandra Santos-Jasso, José Luis Arredondo-García, Jorge Maza-Vallejos, Pablo Lezama-Del Valle
PURPOSE: Constipation is present in 80% of children with corrected anorectal malformations, usually associated to rectal dilation and hypomotility. Osmotic laxatives are routinely used for idiopathic constipation. Senna is a stimulant laxative that produces contractions improving colonic motility without affecting the stool consistency. We designed this trial to study the effectiveness of Senna versus polyethylene glycol for the treatment of constipation in children with anorectal malformation...
October 27, 2016: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/27831909/blended-foods-for-tube-fed-children-a-safe-and-realistic-option-a-rapid-review-of-the-evidence
#20
REVIEW
Jane Coad, Alex Toft, Susie Lapwood, Joseph Manning, Mark Hunter, Huw Jenkins, Clare Sadlier, Julie Hammonds, Ailsa Kennedy, Simon Murch, David Widdas
With the growing number of children and young people with complex care needs or life-limiting conditions, alternative routes for nutrition have been established (such as gastrostomy feeding). The conditions of children and young people who require such feeding are diverse but could relate to problems with swallowing (dysphagia), digestive disorders or neurological/muscular disorders. However, the use of a blended diet as an alternative to prescribed formula feeds for children fed via a gastrostomy is a contentious issue for clinicians and researchers...
October 18, 2016: Archives of Disease in Childhood
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