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https://www.readbyqxmd.com/read/28923072/a-childhood-onset-intestinal-toxemia-botulism-during-chemotherapy-for-relapsed-acute-leukemia
#1
Noriko Ohyama, Michiko Torio, Kentaro Nakashima, Yuuki Koga, Shunsuke Kanno, Hisanori Nishio, Kei Nishiyama, Momoko Sasazuki, Haru Kato, Hiroshi Asakura, Satoshi Akamine, Masafumi Sanefuji, Yoshito Ishizaki, Yasunari Sakai, Shouichi Ohga
BACKGROUND: Botulism is a potentially fatal infection characterized by progressive muscle weakness, bulbar paralysis, constipation and other autonomic dysfunctions. A recent report suggested that cancer chemotherapy might increase the risk for the intestinal toxemia botulism in both adults and children. CASE PRESENTATION: We report a 5-year-old boy, who developed general muscle weakness, constipation, ptosis and mydriasis during the third induction therapy for relapsed acute myeloid leukemia...
September 18, 2017: Annals of Clinical Microbiology and Antimicrobials
https://www.readbyqxmd.com/read/28918613/predicting-time-to-reflux-of-children-with-antenatal-hydronephrosis-a-competing-risks-approach
#2
Maryam Nazemipour, Abdol-Mohammad Kajbafzadeh, Kazem Mohammad, Abbas Rahimi Foroushani, Mahmood Mahmoudi
The aim of this study was describing methodological aspects and applying a trivariate Weibull survival model using the competing risks concept to predict time to occurrence different types of reflux (unilateral (left, right) or bilateral) in children with antenatal hydronephrosis. Data from 333 children in Pediatric Urology Research Center of Children's Hospital Medical Center, affiliated with Tehran University of Medical Sciences was used. The effect of some demographic and clinical factors on child's reflux was studied...
July 2017: Acta Medica Iranica
https://www.readbyqxmd.com/read/28915908/advances-in-paediatrics-in-2016-current-practices-and-challenges-in-allergy-autoimmune-diseases-cardiology-endocrinology-gastroenterology-infectious-diseases-neonatology-nephrology-neurology-nutrition-pulmonology
#3
REVIEW
Carlo Caffarelli, Francesca Santamaria, Dora Di Mauro, Carla Mastrorilli, Silvia Montella, Sergio Bernasconi
This review reports main progresses in various pediatric issues published in Italian Journal of Pediatrics and in international journals in 2016. New insights in clinical features or complications of several disorders may be useful for our better understanding. They comprise severe asthma, changing features of lupus erythematosus from birth to adolescence, celiac disease, functional gastrointestinal disorders, Moebius syndrome, recurrent pneumonia. Risk factors for congenital heart defects, Kawasaki disease have been widely investigated...
September 16, 2017: Italian Journal of Pediatrics
https://www.readbyqxmd.com/read/28915401/the-modified-ketogenic-diet-for-adults-with-refractory-epilepsy-an-evaluation-of-a-set-up-service
#4
Kirsty J Martin-McGill, Michael D Jenkinson, Catrin Tudur Smith, Anthony G Marson
PURPOSE: The ketogenic diet (KD) has been proven to be effective in children with refractory epilepsy and is recommended by the National Institute of Health and Care Excellence (NICE). There is no randomised control trial (RCT) evidence for the clinical or cost effectiveness of KD in adults, for whom the KD is not currently recommended. We assessed the feasibility of the modified ketogenic diet (MKD) in adults with refractory epilepsy along with the willingness of patients to participate in a future RCT...
September 1, 2017: Seizure: the Journal of the British Epilepsy Association
https://www.readbyqxmd.com/read/28914984/hypercalcemic-disorders-in-children
#5
REVIEW
Victoria J Stokes, Morten F Nielsen, Fadil M Hannan, Rajesh V Thakker
Hypercalcemia is defined as a serum calcium concentration that is greater than 2 standard deviations above the normal mean, which in children may vary with age and sex, reflecting changes in the normal physiology at each developmental stage. Hypercalcemic disorders in children may present with hypotonia, poor feeding, vomiting, constipation, abdominal pain, lethargy, polyuria, dehydration, failure to thrive and seizures. In severe cases renal failure, pancreatitis and reduced consciousness may also occur and older children and adolescents may present with psychiatric symptoms...
September 15, 2017: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/28914696/the-overlap-of-gastroesophageal-reflux-disease-and-functional-constipation-in-children-the-efficacy-of-constipation-treatment
#6
Masallah Baran, Yeliz Cagan Appak, Miray Karakoyun, Sevda Yalcinkaya, Kayi Eliacik, Bumin N Dundar
OBJECTIVES: This study was designed to investigate the frequency of gastroesophageal reflux disease (GERD) in children with functional constipation (FC). It was structured to assess the improvement level in reflux symptoms by measuring the acid reflux in these patients after they had received FC treatment. METHODS: Ninety-four children who suffered from constipation were evaluated prospectively. Data forms were completed to assess the GERD symptoms in all the cases...
September 13, 2017: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28913814/child-with-abdominal-pain
#7
Rajalakshmi Iyer, Karthi Nallasamy
Abdominal pain is one of the common symptoms reported by children in urgent care clinics. While most children tend to have self-limiting conditions, the treating pediatrician should watch out for underlying serious causes like intestinal obstruction and perforation peritonitis, which require immediate referral to an emergency department (ED). Abdominal pain may be secondary to surgical or non-surgical causes, and will differ as per the age of the child. The common etiologies for abdominal pain presenting to an urgent care clinic are acute gastro-enteritis, constipation and functional abdominal pain; however, a variety of extra-abdominal conditions may also present as abdominal pain...
September 15, 2017: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/28912052/assessing-children-s-report-of-stool-consistency-agreement-between-the-pediatric-rome-iii-questionnaire-and-the-bristol-stool-scale
#8
Mana H Vriesman, Carlos A Velasco-Benitez, Carmen R Ramirez, Marc A Benninga, Carlo Di Lorenzo, Miguel Saps
OBJECTIVES: To assess the agreement between the Questionnaire on Pediatric Gastrointestinal Symptoms-Rome III (QPGS-RIII) and the Bristol Stool Scale (BSS) in evaluating stool consistency and the diagnosis of functional constipation in children. STUDY DESIGN: Children aged 8-18 years were asked to describe their stool consistency in the previous month according to the QPGS-RIII and the BSS. Stool consistency according to both instruments was categorized into 3 categories: "hard," "normal," and "liquid...
September 11, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28906317/polyethylene-glycol-3350-with-electrolytes-vs-polyethylene-glycol-4000-for-constipation-a-randomized-controlled-trial
#9
Noor L H Bekkali, Daniël R Hoekman, Olivia Liem, Marloes E J Bongers, Michiel P van Wijk, Bas Zegers, Rolf A Pelleboer, Wim Verwijs, Bart G P Koot, Maksym Voropaiev, Marc A Benninga
OBJECTIVES: The long-term efficacy and safety of polyethylene glycol (PEG) in constipated children are unknown, and a head-to-head comparison of the different PEG formulations is lacking. We aimed to investigate non-inferiority of PEG3350 with electrolytes (PEG3350+E) compared to PEG4000 without electrolytes (PEG4000). METHODS: In this double-blind trial, children aged 0.5 - 16 years with constipation, defined as a defecation frequency of < 3 times per week, were randomized to receive either PEG3350 + E or PEG4000...
September 12, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28898506/physical-activity-may-decrease-the-likelihood-of-children-developing-constipation
#10
Sandra Seidenfaden, Orri Thor Ormarsson, Sigrun H Lund, Einar S Bjornsson
AIM: Childhood constipation is common. We evaluated children diagnosed with constipation, who were referred to an Icelandic paediatric emergency department, and determined the effect of lifestyle factors on its aetiology. METHODS: The parents of children who were diagnosed with constipation and participated in a phase IIB clinical trial on laxative suppositories answered an online questionnaire about their children's lifestyle and constipation in March-April 2013...
September 12, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/28888814/primary-and-secondary-enuresis-pathophysiology-diagnosis-and-treatment
#11
REVIEW
Bernhard Haid, Serdar Tekgül
CONTEXT: Enuresis is a common and possibly underestimated condition. While 5-10% of school-aged children suffer from the condition, a lack of background knowledge may impede timely child-adapted and successful therapy. OBJECTIVE: To provide a comprehensive overview of the pathophysiology, diagnosis, and treatment of enuresis. EVIDENCE ACQUISITION: Guideline and position papers from the European Society of Pediatric Urology, the European Association of Urology, and the International Children's Continence Society were acquired...
September 6, 2017: European Urology Focus
https://www.readbyqxmd.com/read/28888690/pelvic-physiotherapy-in-addition-to-standard-care-is-more-effective-than-standard-medical-care-alone-for-children-with-functional-constipation-synopsis
#12
Nora Shields
No abstract text is available yet for this article.
September 6, 2017: Journal of Physiotherapy
https://www.readbyqxmd.com/read/28887752/comparison-of-antipyretic-efficacy-of-intravenous-iv-acetaminophen-versus-oral-po-acetaminophen-in-the-management-of-fever-in-children
#13
Shuvendu Roy, A K Simalti
OBJECTIVE: To assess the dynamics of the onset of antipyretic efficacy of intravenous (IV) acetaminophen vs. oral (PO) acetaminophen in the management of fever in children. METHODS: This observational single-dose study was conducted at Department of Pedriatrics, Army Hospital (Research and Referral), a multispecialty tertiary care center in New Delhi in fever patients to assess the antipyretic efficacy of IV acetaminophen 15 mg/kg/dose vs. PO acetaminophen 15 mg/kg/dose over 6 h...
September 9, 2017: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/28875974/-functional-gastrointestinal-disorders-in-children-and-adolescents-the-rome-iv-criteria
#14
REVIEW
Barbara Iwańczak, Franciszek Iwańczak
In the work diagnostic criteria of functional disorders of the gastrointestinal tract in children and adolescents aged 4 to 18 years are presented. The criteria were elaborated by experienced experts in pediatrics and gastroenterology and were presented on Digestive Disease Week in San Diego in 2016 as modified IV Rome Criteria. In the work the following functional disorders are discussed: cyclic vomiting syndrome, functional nausea and vomiting, rumination syndrome, aerophagia, functional dyspepsia, irritable bowel syndrome, abdominal migraine, functional abdominal pain - not otherwise specified, functional constipation, nonretentive fecal incontinence...
August 21, 2017: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/28869807/prolonged-toilet-training-in-children-with-down-syndrome-a-case-control-study
#15
Flávia Cristina de Carvalho Mrad, André Avarese de Figueiredo, José de Bessa, José Murillo Bastos Netto
OBJECTIVES: Children with Down syndrome have delayed psychomotor development, which is a factor that influences the level of difficulty in toilet training. The current study aims to estimate the age toilet training starts and completes in children with DS compared to children with normal psychomotor development and to evaluate the method and type of toilet training most frequently used, as well as its association with lower urinary tract symptoms and functional constipation. METHODS: A case-control study was carried out from 2010 to 2015...
September 1, 2017: Jornal de Pediatria
https://www.readbyqxmd.com/read/28867160/children-with-nocturnal-enuresis-and-attention-deficit-hyperactivity-disorder-a-separate-entity
#16
Larisa Kovacevic, Cortney Wolfe-Christensen, Aliza Rizwan, Hong Lu, Yegappan Lakshmanan
INTRODUCTION: There is ongoing debate about whether nocturnal enuresis (NE) is affected by the presence of attention deficit hyperactivity disorder (ADHD) in children. Clarifying this relationship could categorize them as a separate entity, potentially requiring a different management from enuretic children without ADHD. AIMS: To study whether (1) children with ADHD exhibited greater severity of enuresis and associated voiding symptoms compared with children without ADHD, (2) whether there was a difference in enuretic response to treatment between children with/without ADHD, (3) whether previously prescribed medication for ADHD affected severity of enuresis or voiding symptoms, and response to treatment...
August 3, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28865084/eosinophilic-esophagitis-in-children-under-the-age-of-5-years-clinical-characteristics
#17
Ravi W Sun, Juliana Bonilla-Velez, Robert D Pesek, Adam B Johnson, Mario A Cleves, Gresham T Richter
OBJECTIVES/HYPOTHESIS: To delineate clinical characteristics and treatment outcomes of eosinophilic esophagitis (EoE) in the youngest of children. STUDY DESIGN: Retrospective chart review. METHODS: A 7-year retrospective chart review of children with clinicopathologic diagnosis of EoE was performed with specific analysis of patients under 5 years old. EoE was defined as the presence of symptoms of esophageal dysfunction with pathologically proven eosinophilic inflammation (≥15 eosinophils per high-power field [EOS/HPF]) unresponsive to reflux therapy...
September 2, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28837513/prospective-study-of-gastrointestinal-symptoms-in-school-children-of-south-america
#18
Miguel Saps, Carlo A Velasco-Benitez, Puck J J Bloom, Marc A Benninga, Diana X Nichols-Vinueza
OBJECTIVES: To establish the prevalence of abdominal pain (AP) in school-children in Pasto (Colombia) and determine the impact of AP on their daily activities; and compare the prevalence of AP and other gastrointestinal symptoms between school-children from Pasto and Chicago. METHODS: Fourth and fifth-grade students from a public school and a private school in Colombia were invited to participate in a prospective study using the same methods and questionnaires (Spanish version) as a previous study conducted in Chicago schools...
August 23, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28835820/the-coexistence-of-psychiatric-and-gastrointestinal-problems-in-children-with-restrictive-eating-in-a-nationwide-swedish-twin-study
#19
Jakob Täljemark, Maria Råstam, Paul Lichtenstein, Henrik Anckarsäter, Nóra Kerekes
BACKGROUND: Restrictive eating problems are rare in children but overrepresented in those with neurodevelopmental problems. Comorbidities decrease wellbeing in affected individuals but research in the area is relatively scarce. This study describes phenotypes, regarding psychiatric and gastrointestinal comorbidities, in children with restrictive eating problems. METHODS: A parental telephone interview was conducted in 9- or 12-year old twins (n = 19,130) in the Child and Adolescent Twin Study in Sweden...
2017: Journal of Eating Disorders
https://www.readbyqxmd.com/read/28834055/cost-effectiveness-of-sacral-neuromodulation-for-chronic-refractory-constipation-in-children-and-adolescents-a-markov-model-analysis
#20
A A van der Wilt, H H M Groenewoud, M A Benninga, C D Dirksen, C G M I Baeten, N D Bouvy, J Melenhorst, S O Breukink
AIM: The study aimed to assess the cost-effectiveness of sacral neuromodulation (SNM) compared with conservative treatment in children and adolescents with constipation refractory to conservative treatment. METHOD: A Markov probabilistic model was used, comparing costs and effectiveness of SNM and conservative treatment in children and adolescents aged 10 to 18 years with constipation refractory to conservative treatment. Input for the model regarding transition probabilities, utilities and healthcare costs was based on data from a cohort of patients treated in our centre...
August 22, 2017: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
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