keyword
https://read.qxmd.com/read/38111778/gastric-inflammatory-myofibroblastic-tumor-a-rare-mesenchymal-neoplasm-a-case-report
#1
Manuel Fernandez Rodriguez, Pedro Joaquin Artuñedo Pe, Alejandro Callejas Diaz, Gala Silvestre Egea, Cristián Grillo Marín, Eva Iglesias Garcia, Jose Luis Lucena de La Poza
BACKGROUND: The inflammatory myofibroblastic tumor (IMT) is a rare mesenquimal tumor of doubtful biological behaviour. It's characterised for affecting mainly children and young adults, although it can appear at any age, being the lungs the primary affected organ (in children it represents 20% of all primary pulmonary tumors). CASE SUMMARY: We present the case of a 45 year old woman, with a computed tomography (CT) finding of injury on the anterior surface of the fundus/gastric body and a solid perigastric injury of 12 mm in the ecoendoscopy...
November 27, 2023: World Journal of Gastrointestinal Surgery
https://read.qxmd.com/read/37692736/jejunal-gastrointestinal-stromal-tumor-a-strange-cause-of-massive-gastrointestinal-bleeding
#2
Daniela Martins, Pedro Costa, Gonçalo Guidi, Pedro Pinheiro, João A Pinto-de-Sousa
Jejunal gastrointestinal stromal tumors (GIST) are rare mesenchymal tumors of the gastrointestinal (GI) tract and a rare cause of massive GI bleeding. Due to this rarity and non-specific presentation, diagnosis and treatment may be difficult and often delayed. Urgent surgical intervention is crucial for controlling the source of bleeding and total tumor excision. Herein, we present the case of a 40-year-old male who presented to the emergency room (ER) with features of upper GI bleeding. He referred astheny and black stools, and was pale, sweaty, and tachycardic despite normal blood pressure...
August 2023: Curēus
https://read.qxmd.com/read/37364850/oxidative-stress-induced-by-pollonein-laao-a-new-l-amino-acid-oxidase-from-bothrops-moojeni-venom-prompts-prostate-tumor-spheroid-cell-death-and-impairs-the-cellular-invasion-process-in-vitro
#3
JOURNAL ARTICLE
Lorena Polloni, Tássia Rafaella Costa, Lorena Pinheiro Morais, Bruna Cristina Borges, Samuel Cota Teixeira, Thales Alves de Melo Fernandes, Lucas Ian Veloso Correia, Luciana Machado Bastos, Fernanda Gobbi Amorim, Loïc Quinton, Andreimar Martins Soares, Marcelo José Barbosa Silva, Eloisa Amália Vieira Ferro, Daiana Silva Lopes, Veridiana de Melo Rodrigues Ávila
Cancer cells produce abnormal levels of reactive oxygen species (ROS) that contribute to promote their malignant phenotype. In this framework, we hypothesized that the change in ROS concentration above threshold could impair key events of prostate cancer cells (PC-3) progression. Our results demonstrated that Pollonein-LAAO, a new L-amino acid oxidase obtained from Bothrops moojeni venom, was cytotoxic to PC-3 cells in two-dimensional and in tumor spheroid assays. Pollonein-LAAO was able to increase the intracellular ROS generation that culminates in cell death from apoptosis by both intrinsic and extrinsic pathways due to the up-regulation of TP53, BAX, BAD, TNFRSF10B and CASP8...
June 24, 2023: Cellular Signalling
https://read.qxmd.com/read/36542594/-ceccum-leiomyoma-an-unusual-cause-of-intestinal-occlusion-in-adults
#4
JOURNAL ARTICLE
Lucas Muratore, Luis Gramática, Gastón Benjamín Moretti
INTRODUCTION: Cecal leiomyoma is a very rare benign tumor of the colon, constituted by a proliferative process of smooth muscle that originates from the muscularis propria or the muscularis of the cecum mucosa. These are often asymptomatic tumors that are found incidentally during screening studies or in the context of some other pathology. In cases with clinical expression, it commonly presents as chronic abdominal pain or a palpable abdominal mass. Infrequently it manifests as complications such as intestinal perforation, intestinal bleeding, or intestinal obstruction that require surgical treatment...
December 21, 2022: Revista de la Facultad de Ciencias Médicas
https://read.qxmd.com/read/36333095/recurrent-meningeal-malignant-tumor-assessment-of-differences-in-the-solitary-fibrous-tumor-hemangiopericytoma-spectrum-through-a-case-report
#5
Carlos Sánchez Fernández, Elena García Lagarto, Carlos Alberto Rodríguez-Arias
Solitary fibrous tumors (SFTs) are neoplasms that grow from mesenchymal fusiform cells. In the central nervous system, meninges are the common origin of these neoplasms. Although literature reports mostly SFT as benign neoplasm, malignancy data have been described in recurrences or metastatic lesions. Definitive diagnosis includes immunohistochemical profiles assessing cellular positivity for CD34, vimentin, CD99 and Bcl-2. Recent studies have demonstrated NAB2-STAT6 gene fusion as a distinct molecular feature of SFT with overexpression of the fusion protein NAB2-STAT6 in nuclei of these cells...
November 2022: Neurocirugía (English Edition)
https://read.qxmd.com/read/35483770/-lipoblastoma-like-tumor-of-the-vulva-a-case-report-and-review-of-the-literature
#6
REVIEW
Carmen Vásquez-Dongo, Antoni Rivas, Berta Ferrer, Domingo Bodet, Claudia Valverde, Clara Delbene, Santiago Ramón Y Cajal, Cleofé Romagosa
Lipoblastoma-like tumor of the vulva (LBLTV) was first described as a benign mesenchymal neoplasia; it was not recognized as a separate diagnosis in the 2013 WHO classification of soft-tissue tumors. To date, only 19 cases have been reported. LBLTV differential diagnosis includes other tumors of the vulvoperineal region and tumors with adipocytic differentiation, most of which are benign and thus a misdiagnosis has few clinical consequences. However, LBLTV may also mimic some aggressive lipomatous neoplasms...
April 2022: Revista Española de Patología
https://read.qxmd.com/read/34801049/inflammatory-myofibroblastic-tumour-of-an-unusual-presentation-in-the-uterine-cervix-a-case-report
#7
JOURNAL ARTICLE
Alfonso López de Sa, Alejandro Pascual, Javier Garcia Santos, Ramiro Mendez, Monica Bellon, Mar Ramirez, Fatima Matute, Cristina Del Arco, Aránzazu Manzano, Pluvio Coronado, Antonio Casado, Gloria Marquina
BACKGROUND: Inflammatory myofibroblastic tumour is an infrequent mesenchymal neoplasia of unknown aetiology and variable behaviour, ranging from rather benign lesions to locally aggressive and even metastatic disease. Its presence has been described in almost all organs; however, its location in the female genital tract has rarely been reported. CASE PRESENTATION: We present the case of a 47-year-old female, who was studied in our institution for a recent medical history of several weeks of dyspareunia and abdominal pain...
November 20, 2021: World Journal of Surgical Oncology
https://read.qxmd.com/read/33903024/the-phosphaturic-mesenchymal-tumor-as-a-cause-of-oncogenic-osteomalacia-three-cases-and-review-of-the-literature
#8
JOURNAL ARTICLE
M Moreno Romero, I Pérez Muñoz, F González Lizán, J I Gallego Rivera, L Valdivielso Cañas
INTRODUCTION: The phosphaturic mesenchymal tumour (PMT) is a very uncommon cause of oncogenic osteomalacia (OO), which is a paraneoplastic syndrome with severe clinical osteomalacia. The PMT is a neoplasia that produces the fibroblast growth factor FGF23, resulting in reduced proximal tubular phosphate reabsorption leading to hyperphosphaturia and hypophosphatemia. Our aim is to present our experience and complications in diagnosis and treatment of PMT in three patients. MATERIAL AND METHODS: We propose an observational, descriptive and retrospective study of three cases of OO secondary to PMT found in our database of bone and soft tissue tumours...
April 23, 2021: Revista española de cirugía ortopédica y traumatología
https://read.qxmd.com/read/33455696/ileal-intussusception-in-an-adult-caused-by-a-locally-invasive-inflammatory-fibroid-polyp-a-case-report
#9
Luiz M Nova, Paul Lopez, Clara Cerezo, Concepción Llanos, Irene Amat
Inflammatory fibroid polyps (IFPs) are rare mesenchymal neoplasms affecting the gastrointestinal tract which are considered benign and noninvasive. We present a case of an invasive IFP in a 46-year-old woman who presented with signs of intestinal obstruction due to ileal intussusception. A segment of the small intestine was resected and subsequently intestinal continuity was restored. A polypoid lesion was found obstructing the lumen. Histopathology revealed a mesenchymal proliferation of spindle and stellate cells, without cytological atypia, arranged in a fibromyxoid stroma...
January 2021: Revista Española de Patología
https://read.qxmd.com/read/32963385/gastric-leiomyoma-casusing-gastrointestinal-bleeding
#10
JOURNAL ARTICLE
Enrique Cervantes-Pérez, Gabino Cervantes-Guevara, Lorena A Cervantes-Pérez, Guillermo A Cervantes-Cardona, Alejandro González-Ojeda, Clotilde Fuentes-Orozco
Los leiomiomas gástricos son tumoraciones submucosas benignas, poco comunes, que se originan del músculo liso. Clínicamente son asintomáticos, con buen pronóstico y con pocas complicaciones a largo plazo. Reportamos el caso de un joven de 16 años que se presenta a la clínica con melena y dolor abdominal. En la endoscopia se reporta una tumoración prepilórica, ulcerada y cubierta de fibrina. El estudio histopatológico mostró una neoplasia mesenquimal con positividad inmunohistoquimica para desmina y actina, así como negatividad para C-kit, DOG-1 y S-100, compatible con leiomioma gástrico...
2020: Cirugia y Cirujanos
https://read.qxmd.com/read/32473814/osteogenic-in-vitro-training-of-bone-marrow-mesenquimal-cells-for-application-in-segmentary-bone-resections
#11
JOURNAL ARTICLE
M Godino Izquierdo
OBJECTIVE: To achieve bone continuity in an experimental model of segmental resection of femur bone by applying a treatment with committed to osteogenic bone linage mesenchymal stem cells. MATERIAL AND METHOD: Bone marrow mesenchymal stem cells, obtained from syngeneic Wistar murine, were committed into osteogenic lineage and embedded within a hydroxipatite block. They were implanted in an experimentally created diaphyseal femur resection model. The diaphysis was synthetized with a 1...
July 2020: Revista española de cirugía ortopédica y traumatología
https://read.qxmd.com/read/26509654/ror1-contributes-to-melanoma-cell-growth-and-migration-by-regulating-n-cadherin-expression-via-the-pi3k-akt-pathway
#12
JOURNAL ARTICLE
Natalia Brenda Fernández, Daniela Lorenzo, María Elisa Picco, Gastón Barbero, Leonardo Sebastián Dergan-Dylon, María Paula Marks, Hernán García-Rivello, Liliana Gimenez, Vivian Labovsky, Luca Grumolato, Pablo Lopez-Bergami
The Receptor tyrosine kinase-like Orphan Receptor 1 (ROR1) is primarily expressed by neural crest cells during embryogenesis. Following a complete downregulation after birth, ROR1 was shown to re-express in various types of cancers. Little is known about ROR1 expression and function in melanoma. Here we show that ROR1 is aberrantly expressed in both melanoma cell lines and tumors and that its expression associates with poor Post-Recurrence Survival of melanoma. Using gain- and loss-of-function approaches we found that ROR1 enhances both anchorage-dependent and -independent growth of melanoma cells...
November 2016: Molecular Carcinogenesis
https://read.qxmd.com/read/25102674/-primary-ovarian-carcinosarcoma-report-of-eight-cases
#13
JOURNAL ARTICLE
Gonzalo Montalvo-Esquivel, José Gregorio Chanona-Vilchis, Angel Herrera-Gómez, Antelmo Abelardo Meneses-García, David Isla-Ortiz
BACKGROUND: The carcinosarcoma, or Mixed Mullerian Malign Tumors, represent 1% of malignant ovarian neoplasm, they are formed by a component epithelium and another mesenquimal malignant both. OBJECTIVE: Report the experience of the Ginecological Department of the Instituto Nacional de Cancerología (Mexico) in the treatment of patients with ovarian carcinosarcoma or primary malignant of the ovary. METHODS: A retrospective of 8 cases of carcinosarcoma primary of ovary at National Institute of Cancerology, from January, 2005 to December, 2008...
July 2014: Ginecología y Obstetricia de México
https://read.qxmd.com/read/24438756/emergency-right-hemicolectomy-for-inflammatory-cecal-masses-mimicking-acute-appendicitis
#14
JOURNAL ARTICLE
Hakan Guven, Bora Koc, Fazil Saglam, Irem Akin Bayram, Gokhan Adas
BACKGROUND: Unexpected inflammatory cecal masses of uncertain etiology, encountered in the emergency surgical departments can be indistinguishable, and appropriate operative management of these cases is a dilemma for the surgeons. METHODS: Over a 30-months period between January 2009 and June 2011, a series of 3032 patients who live in sub-urban underwent emergency surgery for clinical diagnosis of acute appendicitis and ileocecal resection or right hemicolectomy for inflammatory cecal mass were performed in 48 patients...
January 20, 2014: World Journal of Emergency Surgery: WJES
https://read.qxmd.com/read/22089677/-intrapancreatic-lipoma-a-rare-mesenquimatous-tumor-with-an-uncertain-physiopathogenesis
#15
JOURNAL ARTICLE
Alexander Lozano Samaniego, Yukiyosi Kimura Fujikami, Sergio Criales Vera, Miguel Stoopen Rometti
Intrapancreatic lipoma is a mesenquimal tumor that currently is still considered a strange entity. There are numerous hypotheses about its pathophysiology; however, none has been clarified. Diagnosis is usually incidental, and computed tomography has been performed for other indications, with high sensibility and specificity, making histopathology confirmation unnecessary, hence suggesting image-follow up solely.
September 2011: Gaceta Médica de México
https://read.qxmd.com/read/19946100/can-mdm2-and-cdk4-make-the-diagnosis-of-well-differentiated-dedifferentiated-liposarcoma-an-immunohistochemical-study-on-129-soft-tissue-tumours
#16
JOURNAL ARTICLE
P B Aleixo, A A Hartmann, I C Menezes, R T Meurer, A M Oliveira
BACKGROUND: Well differentiated liposarcomas (WDLPS) and dedifferentiated liposarcomas (DDLPS) have been shown to have supernumerary chromosomes with amplified sequences of the MDM2 and CDK4 genes. MDM2 and CDK4 protein overexpression have also been identified in these tumours. AIM: To investigate whether immunohistochemistry (IHC) for MDM2 and CDK4 can be used to diagnose WDLPS and DDLPS. METHODS: IHC for MDM2/CDK4 was carried out on a series of 129 paraffin-embedded lipomatous and non-lipomatous soft tissue tumours...
December 2009: Journal of Clinical Pathology
https://read.qxmd.com/read/18314657/-vesical-hemangioma
#17
REVIEW
S Martín Martín, C Muller Arteaga, V Gonzalo Rodríguez, E García Lagarto, J Egea Camacho, E Fernández del Busto
Bladder hemangiomas are mesenquimal tumors, generally benign and of difficult diagnosis, representing only 0.6% primary bladder tumors. Fundamental diagnosis is histological, since imaging test can't differenciate this from other bladder tumors. We present a case of a 60-year-old male who came to our service with macroscopic hematuria. RTU of one blue mass in the bladder was performed and the histological examination showed to be cavernous hemangioma. A review of literature was realized, commenting on the most typical clinical aspects, the diagnostic methods and the last therapeutic techniques in this type of lesions...
November 2007: Actas Urologicas Españolas
https://read.qxmd.com/read/14735869/-solitary-fibrous-tumor-two-additional-cases-with-urologic-implications
#18
REVIEW
L Xambre, R Lages, M Cerqueira, V Silva, R Prisco, R Santos, F Carreira, M Honavar
Solitary fibrous tumour is a well defined pathological entity originally described as a tumour of the pleura, but the occurrence of this neoplasm has increasingly been described at other sites. At present the development of these tumours is recognized as possible in virtually all anatomical sites. The rarity of this type of pathology has not allowed up to the present time clarification of the histogenesis, clinical behaviour, treatment and prognosis of these tumours. Differential diagnosis becomes important, especially in extra-thoracic sites so as not to mistake them for much more aggressive mesenquimal tumours...
November 2003: Actas Urologicas Españolas
https://read.qxmd.com/read/12068367/-solitary-fibrous-tumor-of-the-meninges-case-report
#19
REVIEW
Ricardo Silva Centeno, Alessandra Augusta Gorgulho Pedroso, Emilio Marcelo Pereira, Aziz Rassi Neto
The solitary fibrous tumor (SFT) is a rare mesenquimal neoplasm, found originally in association with the pleura. Recently, SFT was reported in others sites. The extension into adjacent structures is not uncommon. The meningeal involvement by SFT is rare and there has only twenty-six cases been reported previously in the literature. We report a case of a 25 years-old female patient with generalized tonic clonic seizures in the last six years. During the neurologic investigation, a tumor in the left occipital region of the brain was found...
June 2002: Arquivos de Neuro-psiquiatria
1
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.