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https://www.readbyqxmd.com/read/28515383/a-new-agonist-for-peroxisome-proliferationactivated-receptor-%C3%AE-ppar%C3%AE-fraglide-1-from-zhenjiang-fragrant-vinegar-screening-and-characterization-based-on-cell-culture-experiments
#1
Yoshio Tsujino
Zhenjiang fragrant vinegar (Kozu) is a black rice vinegar that has been used as a traditional Chinese medicine and has various health benefits, including anti-obesity effects. In the present study, using luciferase reporter assays of PPARγ promoter activity, a novel ingredient from 8-year-old Kozu, 5-hydroxy-4-phenyl-butenolide, was isolated. The newly found agonist was named as "Fraglide-1". Moreover, in subsequent experiments, it was confirmed that fraglide-1 was an PPARγ agonist and it could increase expression level of the uncoupling protein (UCP)-1...
May 17, 2017: Journal of Oleo Science
https://www.readbyqxmd.com/read/28484998/enhanced-methane-production-of-vinegar-residue-by-response-surface-methodology-rsm
#2
Jiayu Feng, Jiyu Zhang, Jiafu Zhang, Yanfeng He, Ruihong Zhang, Chang Chen, Guangqing Liu
As the by-product of the vinegar production process, a large number of vinegar residue has been abandoned and caused a serious environmental pollution. Anaerobic digestion has been proved to be able to dispose and convert vinegar residue into bioenergy but still need to improve the efficiency. This study applied central composite design of response surface methodology to investigate the influences of feed to inoculum ratio, organic loading, and initial pH on methane production and optimize anaerobic digestion condition...
December 2017: AMB Express
https://www.readbyqxmd.com/read/28449995/melatonin-in-grapes-and-grape-related-foodstuffs-a-review
#3
REVIEW
Jiang-Fei Meng, Tian-Ci Shi, Shuo Song, Zhen-Wen Zhang, Yu-Lin Fang
A decade has passed since melatonin was first reported in grapes in 2006. During this time, melatonin has not only been found in the berries of most wine grape (Vitis vinifera L.) cultivars, but also in most grape-related foodstuffs, e.g. wine, grape juice and grape vinegar. In this review, we discuss the melatonin content in grapes and grape-related foodstuffs (especially wine) from previous studies, the physiological function of melatonin in grapes, and the factors contributing to the production of melatonin in grapes and wines...
September 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28445412/assessing-the-efficacy-of-first-aid-measures-in-physalia-sp-envenomation-using-solution-and-blood-agarose-based-models
#4
Christie L Wilcox, Jasmine L Headlam, Thomas K Doyle, Angel A Yanagihara
Stings from the hydrozoan species in the genus Physalia cause intense, immediate skin pain and elicit serious systemic effects. There has been much scientific debate about the most appropriate first aid for these stings, particularly with regard to whether vinegar use is appropriate (most current recommendations recommend against vinegar). We found that only a small percentage (≤1.0%) of tentacle cnidae discharge during a sting event using an ex vivo tissue model which elicits spontaneous stinging from live cnidarian tentacles...
April 26, 2017: Toxins
https://www.readbyqxmd.com/read/28444830/gene-expression-reveals-evidence-for-egfr-dependent-proximal-distal-limb-patterning-in-a-myriapod
#5
Ralf Janssen
Evolution of segmented limbs is one of the key innovations of Arthropoda, allowing development of functionally specific specialized head and trunk appendages, a major factor behind their unmatched evolutionary success. Proximodistal limb patterning is controlled by two regulatory networks in the vinegar fly Drosophila melanogaster, and other insects. The first is represented by the function of the morphogens Wingless (Wg) and Decapentaplegic (Dpp); the second by the EGFR-signaling cascade. While the role of Wg and Dpp has been studied in a wide range of arthropods representing all main branches, that is, Pancrustacea (= Hexapoda + Crustacea), Myriapoda and Chelicerata, investigation of the potential role of EGFR-signaling is restricted to insects (Hexapoda)...
April 26, 2017: Evolution & Development
https://www.readbyqxmd.com/read/28444365/evaluation-of-attractants-for-monitoring-drosophila-suzukii-diptera-drosophilidae
#6
Andrew J Frewin, Justin Renkema, Hannah Fraser, Rebecca H Hallett
Drosophila suzukii Matsumura is an economically important pest of soft and small fruit crops. Unlike other drosophilid flies, D. suzukii is capable of infesting ripe and partially ripe fruit, which poses a significant pest management challenge, as there is no tolerance for infested or damaged fruit in the marketplace. As a result, producers in many regions rely on calendar-scheduled insecticide applications for D. suzukii management. In order to develop an integrated pest management approach, better tools for monitoring adult fly populations are needed...
April 21, 2017: Journal of Economic Entomology
https://www.readbyqxmd.com/read/28425938/the-sodium-content-of-processed-foods-in-south-africa-during-the-introduction-of-mandatory-sodium-limits
#7
Sanne A E Peters, Elizabeth Dunford, Lisa J Ware, Teresa Harris, Adele Walker, Mariaan Wicks, Tertia van Zyl, Bianca Swanepoel, Karen E Charlton, Mark Woodward, Jacqui Webster, Bruce Neal
BACKGROUND: In June 2016, the Republic of South Africa introduced legislation for mandatory limits for the upper sodium content permitted in a wide range of processed foods. We assessed the sodium levels of packaged foods in South Africa during the one-year period leading up to the mandatory implementation date of the legislation. METHODS: Data on the nutritional composition of packaged foods was obtained from nutrition information panels on food labels through both in-store surveys and crowdsourcing by users of the HealthyFood Switch mobile phone app between June 2015 and August 2016...
April 20, 2017: Nutrients
https://www.readbyqxmd.com/read/28424779/the-effectiveness-of-various-salacca-vinegars-as-therapeutic-agent-for-management-of-hyperglycemia-and-dyslipidemia-on-diabetic-rats
#8
Elok Zubaidah, Widya Dwi Rukmi Putri, Tiara Puspitasari, Umi Kalsum, Dianawati Dianawati
The aim of this study was to explore the potency of salacca vinegar made from various Indonesian salacca fruit extracts as therapeutic agent for hyperglycemia and dyslipidemia for STZ-induced diabetic rats. The rats were grouped into untreated rats, STZ-induced diabetic rats without treatment, and STZ-induced diabetic rats treated with Pondoh salacca vinegar, Swaru salacca vinegar, Gula Pasir salacca vinegar, Madu salacca vinegar, or Madura salacca vinegar. Parameter observed included blood glucose, total cholesterol (TC), high density lipoprotein (HDL), low density lipoprotein (LDL), triglyceride (TG), malondialdehyde (MDA), superoxide dismutase (SOD), and pancreas histopathology of the samples...
2017: International journal of food science
https://www.readbyqxmd.com/read/28423482/clerosterol-from-vinegar-baked-radix-bupleuri-modifies-drug-transport
#9
Ya Zhao, Li-Min Feng, Li-Juan Liu, Xian Zhang, Rui-Zhi Zhao
Vinegar-baked Radix Bupleuri (VBRB) is reportedly used to treat liver cancer when combined with traditional chemotherapy and data show that this combination may modify drug transport. We isolated clerosterol from VBRB and studied its effect on drug transporters in normal or transporter-overexpressing cells. Transporter activity was assayed using cellular substrate concentration and transporter expression with Western blot and RT-qPCR. Clerosterol decreased cisplatin uptake in BRL cells mainly through increasing Mrp2 gene expression...
March 28, 2017: Oncotarget
https://www.readbyqxmd.com/read/28417109/intractable-methicillin-resistant-staphylococcus-aureus-otorrhea-with-silicone-impression-in-the-middle-ear
#10
Eun Kyung Jung, Chul Ho Jang, Jong Yuap Seong, Yong Beom Cho
We report a case of methicillin-resistant Staphylococcus aureus (MRSA) otorrhea with impression material of hearing aid in the middle ear. The patient had chronic otitis media in the right ear with sensorineural hearing loss in both ears. The silicone flowed into the middle ear through a tympanic membrane perforation during the process of making an ear mold. Several days after hearing aid fitting, the patient had severe otalgia, intractable otorrhea, aggravated hearing loss, and dizziness. The pus culture and sensitivity test revealed MRSA...
April 2017: Journal of Audiology & Otology
https://www.readbyqxmd.com/read/28412648/content-decline-of-serca-inhibitors-saikosaponin-a-and-d-attenuates-cardiotoxicity-and-hepatotoxicity-of-vinegar-baked-radix-bupleuri
#11
Shifeng Wang, Yuxin Zhang, Qiao Zhang, Sha Peng, Chen Shen, Yangyang Yu, Minyu Zhang, Wei Yang, Qinghua Wu, Yanling Zhang, Shiyou Li, Yanjiang Qiao
Improper usage of unprocessed Radix bupleuri root (chaihu) may cause cardiotoxicity and liver injury. Baking herb with vinegar is believed to attenuate the adverse responses. However, the chemical and molecular basis involved remained unclear. To this end, we investigated the in vitro toxicity of saikosaponin a, c, d, and their hydrolysates saikosaponin b1 and b2. Results showed that SSa and SSd possessed higher affinity with sarcoplasmic/endoplasmic reticulum calcium ATPase (SERCA) by molecular docking, and exhibited stronger toxic responses on cardiomyocytes and hepatocytes than the other three saikosaponins in equivalent concentrations...
April 4, 2017: Environmental Toxicology and Pharmacology
https://www.readbyqxmd.com/read/28407890/characterization-and-authentication-of-spanish-pdo-wine-vinegars-using-multidimensional-fluorescence-and-chemometrics
#12
Rocío Ríos-Reina, Saioa Elcoroaristizabal, Juan A Ocaña-González, Diego L García-González, José M Amigo, Raquel M Callejón
This work assesses the potential of multidimensional fluorescence spectroscopy combined with chemometrics for characterization and authentication of Spanish Protected Designation of Origin (PDO) wine vinegars. Seventy-nine vinegars of different categories (aged and sweet) belonging to the Spanish PDOs "Vinagre de Jerez", "Vinagre de Montilla-Moriles" and "Vinagre de Condado de Huelva", were analyzed by excitation-emission fluorescence spectroscopy. A visual assessment of fluorescence landscapes pointed out different trends with vinegar categories...
September 1, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28405368/concurrence-in-the-ability-for-lipid-synthesis-between-life-stages-in-insects
#13
Bertanne Visser, Denis S Willett, Jeffrey A Harvey, Hans T Alborn
The ability to synthesize lipids is critical for an organism's fitness; hence, metabolic pathways, underlying lipid synthesis, tend to be highly conserved. Surprisingly, the majority of parasitoids deviate from this general metabolic model by lacking the ability to convert sugars and other carbohydrates into lipids. These insects spend the first part of their life feeding and developing in or on an arthropod host, during which they can carry over a substantial amount of lipid reserves. While many parasitoid species have been tested for lipogenic ability at the adult life stage, it has remained unclear whether parasitoid larvae can synthesize lipids...
March 2017: Royal Society Open Science
https://www.readbyqxmd.com/read/28401085/physicochemical-qualities-and-flavor-patterns-of-traditional-chinese-vinegars-manufactured-by-different-fermentation-methods-and-aging-periods
#14
Yaping Gao, Yunhee Jo, Namhyeok Chung, Song-Yi Gu, Yong-Jin Jeong, Joong-Ho Kwon
Physicochemical properties of Fujian Yongchun aged vinegar (FYAV) and Shanxi mature vinegar (SMV) were compared in terms of the fermentation methods applied and aging periods (3, 5, 8, and 10 years), and combined E-nose/E-tongue analyses were performed to assess their flavors. Compared with submerged fermentation-derived FYAV, solid-state fermentation-derived SMV showed higher values of pH, brix, soluble solids, total phenolic content, and antioxidant activity, but not total acidity or total organic acids. Aging period resulted in an increase in pH, total phenolic content, and antioxidant activity...
March 2017: Preventive Nutrition and Food Science
https://www.readbyqxmd.com/read/28396985/do-dietary-habits-influence-trace-elements-release-from-fixed-orthodontic-appliances
#15
Paulina Wołowiec, Katarzyna Chojnacka, Bartłomiej W Loster, Marcin Mikulewicz
The objective was to investigate the effect of dietary habits on the release of Cr and Ni ions from orthodontic appliances by hair mineral analysis. Patients (N = 47) underwent electronic questionnaire survey to investigate the effect of dietary habits on Cr and Ni levels in hair. The research was carried out on hair sampled at the beginning and in the 4th, 8th, and 12th months of the treatment. The content of Cr and Ni in the collected samples was determined by ICP-OES. The study showed that consumption of acidic dietary products may have the effect on increasing the release of Cr and Ni ions from orthodontic appliances...
April 11, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/28386890/cooking-can-decrease-mercury-contamination-of-a-mushroom-meal-cantharellus-cibarius-and-amanita-fulva
#16
Jerzy Falandysz, Małgorzata Drewnowska
Mushrooms (Cantharellus cibarius and Amanita fulva) were blanched (parboiled) and pickled using different treatment conditions with the aim of carrying out the study into effect on removal of toxic mercury (Hg) accumulated in flesh. Blanching of fresh sliced C. cibarius caused leaching of Hg by approximately 15%, while loss of up to 35% was observed for sliced, deep-frozen fruit bodies. The rate of Hg leaching from the C. cibarius in practice was the same when blanched for 5 or 15 min irrespective of potable or deionized water used...
April 6, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28378570/evaluation-of-the-antioxidant-property-and-effects-in-caenorhabditis-elegans-of-xiangxi-flavor-vinegar-a-hunan-local-traditional-vinegar
#17
Run-Ting Huang, Qing Huang, Gen-Liang Wu, Chun-Guang Chen, Zong-Jun Li
Xiangxi flavor vinegar (XV) is one of Hunan Province's traditional fermented vinegars. It is produced from herb, rice, and spring water with spontaneous liquid-state fermentation techniques. In this study, we investigated the antioxidant property of XV by analyzing its antioxidant compounds, its free radical scavenging property in vitro and in vivo, and its effects on antioxidant enzyme activity and apoptosis in Caenorhabditis elegans. The results showed that XV is rich in antioxidants. In particular, ligustrazine reached 6...
2017: Journal of Zhejiang University. Science. B
https://www.readbyqxmd.com/read/28372238/metabolite-profiling-and-volatiles-of-pineapple-wine-and-vinegar-obtained-from-pineapple-waste
#18
Arianna Roda, Luigi Lucini, Fabrizio Torchio, Roberta Dordoni, Dante Marco De Faveri, Milena Lambri
Vinegar is an inexpensive commodity, and economic considerations require that a relatively low-cost raw material be used for its production. An investigation into the use of a new, alternative substrate - pineapple waste - is described. This approach enables the utilization of the pineapple's (Ananas comosus) peels and core, which are usually discarded during the processing or consumption of the fruit. Using physical and enzymatic treatments, the waste was saccharified, and the resulting substrate was fermented with Saccharomyces cerevisiae for 7-10days under aerobic conditions at 25°C...
August 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/28369909/determination-of-the-free-amino-acid-organic-acid-and-nucleotide-in-commercial-vinegars
#19
Yan Kong, Li-Li Zhang, Ying Sun, Yu-Yu Zhang, Bao-Guo Sun, Hai-Tao Chen
The selected taste-active compounds in several kinds of commercial vinegar including amino acids, organic acids, and nucleotides were determined by High Performance Liquid Chromatography (HPLC). The results showed that glutamine and alanine, which contribute the umami and sweet taste to the flavor of vinegar, are high in Taste Activity Value (TAV). Acetic acid is the major organic acid in vinegar, making up as much as 91.4% of the total organic acid composition. Nucleotides, which were only detected in 5 brands of commercial vinegar and are both low in TAV, contribute less taste in vinegar...
May 2017: Journal of Food Science
https://www.readbyqxmd.com/read/28364663/tissue-growth-and-tumorigenesis-in-drosophila-cell-polarity-and-the-hippo-pathway
#20
REVIEW
Helena E Richardson, Marta Portela
Cell polarity regulation is critical for defining membrane domains required for the establishment and maintenance of the apical-basal axis in epithelial cells (apico-basal polarity), asymmetric cell divisions, planar organization of tissues (planar cell polarity), and the formation of the front-rear axis in cell migration (front-rear polarity). In the vinegar fly, Drosophila melanogaster, cell polarity regulators also interact with the Hippo tissue growth control signaling pathway. In this review we survey the recent Drosophila literature linking cell polarity regulators with the Hippo pathway in epithelial tissue growth, neural stem cell asymmetric divisions and in cell migration in physiological and tumorigenic settings...
March 28, 2017: Current Opinion in Cell Biology
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