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https://www.readbyqxmd.com/read/28087323/severe-hemorrhagic-syndrome-after-lonomia-caterpillar-envenomation-in-the-western-brazilian-amazon-how-many-more-cases-are-there
#1
João Hugo A Santos, Sâmella S Oliveira, Eliane C Alves, Iran Mendonça-da-Silva, Jacqueline A G Sachett, Antonio Tavares, Luiz Carlos Ferreira, Hui Wen Fan, Marcus V G Lacerda, Wuelton M Monteiro
Contact with Lonomia caterpillars can cause a hemorrhagic syndrome. In Brazil, Lonomia obliqua and Lonomia achelous are known to cause this venom-induced disease. In the Brazilian Amazon, descriptions of this kind of envenomation are scarce. Herein, we report a severe hemorrhagic syndrome caused by Lonomia envenomation in the Amazonas state, Western Brazilian Amazon. The patient showed signs of hemorrhage lasting 8 days and required Lonomia antivenom administration, which resulted in resolution of hemorrhagic syndrome...
January 10, 2017: Wilderness & Environmental Medicine
https://www.readbyqxmd.com/read/28087113/video-assisted-thoracoscopic-diaphragm-plication-using-a-running-suture-technique-is-durable-and-effective
#2
David S Demos, Mark F Berry, Leah M Backhus, Joseph B Shrager
OBJECTIVE: Surgeons have hesitated to adopt minimally invasive diaphragm plication techniques because of technical limitations rendering the procedure cumbersome or leading to early failure or reduced efficacy. We sought to demonstrate efficacy and durability of our thoracoscopic plication technique using a single running suture. METHODS: We retrospectively reviewed patients who underwent our technique for diaphragm plication since 2008. We used a single, buttressed, double-layered, to-and-fro running suture with additional plicating horizontal mattress sutures as needed...
December 21, 2016: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28081584/-mini-open-approach-shows-good-results-in-treatment-of-femoroacetabular-impingement
#3
Stephanie Maria Kirschbaum, Frank Sitterlee, Carsten Perka, Michael Müller
Background Femoroacetabular impingement (FAI) describes a painful, abnormal (bony) contact between the femoral neck and acetabulum, which, if left untreated, contributes to early osteoarthritis (OA) of the hip. Despite its flat learning curve and long operation times, hip arthroscopy has been used increasingly often in recent years in the surgery of femoroacetabular impingement. The mini-open technique (MOT) offers a possible alternative that addresses the abnormal morphological prominence and allows minimally invasive clearance of hip motion...
January 12, 2017: Zeitschrift Für Orthopädie und Unfallchirurgie
https://www.readbyqxmd.com/read/28076634/immediate-versus-delayed-treatment-for-recently-symptomatic-carotid-artery-stenosis
#4
Vladimir Vasconcelos, Nicolle Cassola, Edina Mariko Koga da Silva, José Carlos Costa Baptista-Silva
BACKGROUND: The timing of surgery for recently symptomatic carotid artery stenosis remains controversial. Early cerebral revascularization may prevent a disabling or fatal ischemic recurrence, but it may also increase the risk of hemorrhagic transformation, or of dislodging a thrombus. This review examined the randomized controlled evidence that addressed whether the increased risk of recurrent events outweighed the increased benefit of an earlier intervention. OBJECTIVES: To assess the risks and benefits of performing very early cerebral revascularization (within two days) compared with delayed treatment (after two days) for people with recently symptomatic carotid artery stenosis...
November 2016: São Paulo Medical Journal, Revista Paulista de Medicina
https://www.readbyqxmd.com/read/28074719/-ten-tips-for-initial-assessment-and-treatment-of-minor-burns
#5
G L Vlaspolder, A F P M Vloemans, R S Breederveld
The initial care of a patient with burns is a challenge for every doctor. After cooling the burn appropriately, a careful history and a good initial assessment are of essential importance for treatment. The burn should be inspected regularly for early detection of any infection and to evaluate wound healing. If healing has not occurred in two weeks, hypertrophic scarring may develop and surgical treatment should be considered. It is always possible to contact the burns centres in Beverwijk, Rotterdam and Groningen to discuss treatment of the burn, any infection of a wound, consideration of surgical treatment, or transfer of a patient to a burn centre...
2017: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/28074322/decreased-survival-in-glioblastomas-is-specific-to-contact-with-the-ventricular-subventricular-zone-not-subgranular-zone-or-corpus-callosum
#6
Akshitkumar M Mistry, Michael C Dewan, Gabrielle A White-Dzuro, Philip R Brinson, Kyle D Weaver, Reid C Thompson, Rebecca A Ihrie, Lola B Chambless
The clinical effect of radiographic contact of glioblastoma (GBM) with neurogenic zones (NZ)-the ventricular-subventricular (VSVZ) and subgranular (SGZ) zones-and the corpus callosum (CC) remains unclear and, in the case of the SGZ, unexplored. We investigated (1) if GBM contact with a NZ correlates with decreased survival; (2) if so, whether this effect is associated with a specific NZ; and (3) if radiographic contact with or invasion of the CC by GBM is associated with decreased survival. We retrospectively identified 207 adult patients who underwent cytoreductive surgery for GBM followed by chemotherapy and/or radiation...
January 10, 2017: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/28073796/comparative-efficacy-and-tolerability-of-pharmacological-interventions-for-attention-deficit-hyperactivity-disorder-in-children-adolescents-and-adults-protocol-for-a-systematic-review-and-network-meta-analysis
#7
Samuele Cortese, Nicoletta Adamo, Christina Mohr-Jensen, Adrian J Hayes, Sahar Bhatti, Sara Carucci, Cinzia Del Giovane, Lauren Z Atkinson, Tobias Banaschewski, Emily Simonoff, Alessandro Zuddas, Corrado Barbui, Marianna Purgato, Hans-Christoph Steinhausen, Farhad Shokraneh, Jun Xia, Andrea Cipriani, David Coghill
INTRODUCTION: Attention-deficit/hyperactivity disorder (ADHD) is a major public health issue. Pharmacological treatments play an important role in the multimodal treatment of ADHD. Currently, there is a lack of up-to-date and comprehensive evidence on how available ADHD drugs compare and rank in terms of efficacy and tolerability, in children or adolescents as well as in adults. We will conduct a network meta-analysis (NMA), integrating direct and indirect comparisons from randomised controlled trials (RCTs), to rank pharmacological treatments for ADHD according to their efficacy and tolerability profiles...
January 10, 2017: BMJ Open
https://www.readbyqxmd.com/read/28073178/polyclonal-and-monoclonal-antibodies-for-induction-therapy-in-kidney-transplant-recipients
#8
REVIEW
Penny Hill, Nicholas B Cross, A Nicholas R Barnett, Suetonia C Palmer, Angela C Webster
BACKGROUND: Prolonging kidney transplant survival is an important clinical priority. Induction immunosuppression with antibody therapy is recommended at transplantation and non-depleting interleukin-2 receptor monoclonal antibodies (IL2Ra) are considered first line. It is suggested that recipients at high risk of rejection should receive lymphocyte-depleting antibodies but the relative benefits and harms of the available agents are uncertain. OBJECTIVES: We aimed to: evaluate the relative and absolute effects of different antibody preparations (except IL2Ra) when used as induction therapy in kidney transplant recipients; determine how the benefits and adverse events vary for each antibody preparation; determine how the benefits and harms vary for different formulations of antibody preparation; and determine whether the benefits and harms vary in specific subgroups of recipients (e...
January 11, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28071193/screening-of-esbl-producing-enterobacteriacae-concomitant-with-low-degree-of-transmission-in-intensive-care-and-bone-marrow-transplant-units
#9
Giuseppe Valenza, Monika Schulze, Petra Friedrich, Wulf Schneider-Brachert, Thomas Holzmann, Silke Nickel, Verena Lehner-Reindl, Christiane Höller
BACKGROUND: Extended-spectrum β-lactamase-producing Enterobacteriaceae (ESBL-E) are spreading worldwide in both hospital and community settings. In this study, the molecular epidemiology and the transmission modalities of ESBL-E in intensive care- and bone marrow transplant were investigated. METHODS: All patients included in this study were screened for presence of ESBL-E on admission and weekly. Relevant β-lactamase genes were identified by PCR and sequencing...
January 10, 2017: Infectious Diseases
https://www.readbyqxmd.com/read/28065990/delayed-diagnosis-of-an-isolated-posterolateral-corner-injury-a-case-report
#10
Patrick Welsh, Christopher DeGraauw, David Whitty
INTRODUCTION: Isolated injuries to the posterolateral corner of the knee are a rare and commonly missed injury associated with athletic trauma, motor vehicle accidents, and falls. Delayed or missed diagnoses can negatively impact patient prognosis, contributing to residual instability, chronic pain, and failure of surgical repair to other ligaments. CASE PRESENTATION: A 44-year-old male CrossFit athlete presented with a history of two non-contact hyperextension injuries to his left knee while walking on ice...
December 2016: Journal of the Canadian Chiropractic Association
https://www.readbyqxmd.com/read/28056014/prevalence-of-chagas-disease-in-a-u-s-population-of-latin-american-immigrants-with-conduction-abnormalities-on-electrocardiogram
#11
Mahmoud I Traina, Salvador Hernandez, Daniel R Sanchez, Jalal Dufani, Mohsin Salih, Adieb M Abuhamidah, Wilman Olmedo, Jason S Bradfield, Colin J Forsyth, Sheba K Meymandi
Chagas disease (CD) affects over six million people and is a leading cause of cardiomyopathy in Latin America. Given recent migration trends, there is a large population at risk in the United States (US). Early stage cardiac involvement from CD usually presents with conduction abnormalities on electrocardiogram (ECG) including right bundle branch block (RBBB), left anterior or posterior fascicular block (LAFB or LPFB, respectively), and rarely, left bundle branch block (LBBB). Identification of disease at this stage may lead to early treatment and potentially delay the progression to impaired systolic function...
January 5, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28047975/su-f-t-223-radiotherapy-incident-reporting-and-analysis-system-riras-early-experience
#12
R Kapoor, D Burkett, E Leidholdt, J Palta, M Hagan
BACKGROUND & PURPOSE: RIRAS is a web-based information system deployed on the Veterans Health Administration intranet in early 2014 to collect adverse events and good catch data; analyze the causes and contributing factors; and find ways to prevent future occurrences. MATERIAL AND METHODS: Incident learning consists of a feedback loop which starts with reporting an event, followed by analysis of contributing factors, and culminates in the development of a patient safety work product (PSWP) to prevent recurrence...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28045940/applying-the-integrated-practice-unit-concept-to-a-modified-virtual-ward-model-of-care-for-patients-at-highest-risk-of-readmission-a-randomized-controlled-trial
#13
Lian Leng Low, Shu Yun Tan, Matthew Joo Ming Ng, Wei Yi Tay, Lee Beng Ng, Kanchana Balasubramaniam, Rachel Marie Towle, Kheng Hock Lee
BACKGROUND: Emerging evidence from the virtual ward care model showed that multidisciplinary case management are inadequate to reduce readmissions or death for high risk patients. There is consensus that interventions should encompass both pre-hospital discharge and post-discharge transitional care to be effective. Integrated practice units (IPU) had been proposed as an approach of restructuring the organization and work processes of multidisciplinary teams to achieve value in healthcare...
2017: PloS One
https://www.readbyqxmd.com/read/28044348/early-recognition-and-detection-of-juvenile-psoriatic-arthritis-a-call-for-a-standardized-approach-to-screening
#14
E Burden-Teh, K S Thomas, S Rangaraj, J Cranwell, R Murphy
BACKGROUND: National Institute for Health and Care Excellence (NICE) guidelines recommend annual screening for psoriatic arthritis (PsA) in all patients with psoriasis. Currently, no validated assessment tools have been recommended for screening for juvenile PsA (JPsA). AIM: To determine dermatologists' practice when assessing children's joints and explore the challenges dermatologists experience when looking for joint disease, in order to inform future strategies to improve early detection of arthritis...
January 2, 2017: Clinical and Experimental Dermatology
https://www.readbyqxmd.com/read/28043601/best-approaches-to-drug-resistance-surveillance-at-the-country-level
#15
A M Cabibbe, D M Cirillo
In 2014, the World Health Organization (WHO) recommendation to include the endorsed rapid molecular technologies (Xpert MTB/RIF, line probe assays) into surveillance systems and surveys allowed the testing of more tuberculosis (TB) patients for drug resistance at country level than ever before. The whole genome sequencing (WGS) approach is emerging as a more powerful tool for epidemiological and drug-resistant routine surveillances, promising a rapid and simultaneous screening of all the clinically-relevant mutations for the determination of resistance to the first-, second-line, and new anti-TB drugs...
December 2016: International Journal of Mycobacteriology
https://www.readbyqxmd.com/read/28043486/tuberculosis-in-children
#16
Ali Akbar Velayati
Tuberculosis (TB) is the main cause of infection-related death in the world. Children make up ∼5-15% of all TB cases. Severe forms of disease such as meningitis and disseminated form are more common in children. Due to current estimates of World Health Organization (WHO) in 2015, one million children suffer from TB around the world; of these, it is estimated that more than 136,000 die a year. One study estimated 67million children with latent TB which develops to active form with the rate of ∼850,000 each year...
December 2016: International Journal of Mycobacteriology
https://www.readbyqxmd.com/read/28032558/early-learners-as-health-coaches-for-older-adults-preparing-for-surgery
#17
Jennifer A Kaplan, Zabecca Brinson, Rebecca Hofer, Patricia O'Sullivan, Anna Chang, Helen Horvath, George J Chang, Emily Finlayson
BACKGROUND: Few opportunities exist for early learners to engage in authentic roles on health care teams. In a geriatric optimization clinic for frail high-risk surgical patients, first-year medical and nurse practitioner students were integrated into an interprofessional team as health coaches. MATERIALS AND METHODS: Frail surgical patients with planned operations were referred to a new preoperative optimization clinic to see a geriatrician, occupational, and physical therapists and a nutritionist...
October 20, 2016: Journal of Surgical Research
https://www.readbyqxmd.com/read/28031499/mid-term-outcome-of-total-hip-arthroplasty-using-a-short-stem
#18
Rajesh Malhotra, Vijay Kumar
PURPOSE: To review the outcome of total hip arthroplasty (THA) using a short femoral stem in 33 hips. METHODS: Records of 33 hips in 20 men and 10 women aged 25 to 40 (mean, 30) years who underwent cementless THA using a short femoral stem by a single senior surgeon were reviewed. The diagnosis included avascular necrosis (n=9), ankylosing spondylitis (n=12), rheumatoid arthritis (n=7), posttraumatic arthritis (n=4), and Hurler syndrome (n=1). Clinical outcome was assessed using the Harris Hip Score...
December 2016: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/28030595/prognosis-for-hospitalized-patients-with-systemic-lupus-erythematosus-in-china-5-year-update-of-the-jiangsu-cohort
#19
Xuebing Feng, Wenyou Pan, Lin Liu, Min Wu, Fuwan Ding, Huaixia Hu, Xiang Ding, Hua Wei, Yaohong Zou, Xian Qian, Meimei Wang, Jian Wu, Juan Tao, Jun Tan, Zhanyun Da, Miaojia Zhang, Jing Li, Lingyun Sun
OBJECTIVE: To identify early signs associated with poor prognosis in Chinese patients with systemic lupus erythematosus (SLE) through a large population-based follow-up study. METHODS: Medical records of > 2,500 SLE patients that first hospitalized between 1999-2009 were collected from 26 centers across Jiangsu province, China, and entered into a database. These patients were followed-up for 5 to 15 years, and those remained contact and had known survival status in 2015 were assessed for the association of factors presented at the initial hospitalization with mortality at two time points (≤1year and > 1year)...
2016: PloS One
https://www.readbyqxmd.com/read/28003132/frequency-and-morbidity-of-temporomandibular-joint-involvement-in-adult-patients-with-a-history-of-juvenile-idiopathic-arthritis
#20
Cory M Resnick, Rushil Dang, Lauren A Henderson, David A Zander, Kimberly M Daniels, Peter A Nigrovic, Leonard B Kaban
PURPOSE: Most patients with juvenile idiopathic arthritis (JIA) have temporomandibular joint (TMJ) involvement, but little is known about the natural history of TMJ disease as these children enter adulthood. The purpose of this study was to evaluate adults with a history of JIA to document the frequency and severity of TMJ abnormalities and morbidity. The authors hypothesized that most would have persistent TMJ disease as adults. MATERIALS AND METHODS: This cross-sectional study included adults (>19 years of age) with JIA who were managed at Boston Children's Hospital (BCH) as children and at Brigham and Women's Hospital (BWH) as adults...
December 2, 2016: Journal of Oral and Maxillofacial Surgery
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