Xiaobei Zhang, Soumya Ravichandran, Gilbert C Gee, Tien S Dong, Hiram Beltrán-Sánchez, May C Wang, Lisa A Kilpatrick, Jennifer S Labus, Allison Vaughan, Arpana Gupta
IMPORTANCE: Perceived social isolation is associated with negative health outcomes, including increased risk for altered eating behaviors, obesity, and psychological symptoms. However, the underlying neural mechanisms of these pathways are unknown. OBJECTIVE: To investigate the association of perceived social isolation with brain reactivity to food cues, altered eating behaviors, obesity, and mental health symptoms. DESIGN, SETTING, AND PARTICIPANTS: This cross-sectional, single-center study recruited healthy, premenopausal female participants from the Los Angeles, California, community from September 7, 2021, through February 27, 2023...
April 1, 2024: JAMA Network Open