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Psychiatry AND pharmacy

Arton Baftiu, Cecilie Johannessen Landmark, Ida Rudberg Rusten, Silje Andrea Feet, Svein I Johannessen, Pål G Larsson
PURPOSE: The purpose of this study was to investigate changes in utilisation of antiepileptic drugs (AEDs) in epilepsy and non-epilepsy disorders in Norway and furthermore to study the retention rates of the most commonly used AEDs in these indications in long-term use. METHODS: The data consisted of all prescriptions of AEDs from Norwegian pharmacies in the Norwegian Prescription Database (NorPD) (2004-2012). Variables included anonymous data regarding age, gender, diagnosis specific reimbursement codes and utilisation of AEDs...
October 2016: European Journal of Clinical Pharmacology
Casey E Gallimore, Dimmy Sokhal, Elizabeth Zeidler Schreiter, Amanda R Margolis
OBJECTIVE: Patients prescribed psychotropic medications within primary care are at risk of suboptimal monitoring. It is unknown whether pharmacists can improve medication safety through targeted monitoring of at risk populations. Access Community Health Centers implemented a quality improvement pilot project that included pharmacists on an integrated care team to provide medication reviews for patients. Aims were to determine whether inclusion of a pharmacist performing medication reviews within a primary care behavioral health (PCBH) practice is feasible and facilitates safe medication use...
June 2016: Families, Systems & Health: the Journal of Collaborative Family Healthcare
Shoshana J Herzig, Michael B Rothberg, Jamey R Guess, Jennifer P Stevens, John Marshall, Jerry H Gurwitz, Edward R Marcantonio
OBJECTIVES: To investigate patterns and predictors of use of antipsychotics in hospitalized adults. DESIGN: Retrospective cohort study. SETTING: Academic medical center. PARTICIPANTS: Individuals aged 18 and older hospitalized from August 2012 to August 2013, excluding those admitted to obstetrics and gynecology or psychiatry or with a psychotic disorder. MEASUREMENTS: Use was ascertained from pharmacy charges...
February 2016: Journal of the American Geriatrics Society
Takuya Shimane
  The non-medical use or abuse of prescription drugs, including benzodiazepines, is a growing health problem in Japan. An association between prescription drug overdose and suicide risk has also been reported. The Japanese Ministry of Health, Labour and Welfare has expected pharmacists to act as "gatekeepers", facilitating early identification of individuals at high risk of prescription drug abuse including overdose, supplying medication counseling to patients, and helping to introduce these patients to appropriate medical care...
2016: Yakugaku Zasshi: Journal of the Pharmaceutical Society of Japan
Alejandro Ferrero
Research in psychopharmacology began around 1950 with the description of antipsychotic effect of chlorpromazine followed shortly later with the mechanism of action of antidepressants. In these initial phases, pharmacy industry was open to knowledge and made efforts tending to the development to new drugs that showed efficacy and good safety profiles. In parallel development of theories attempting to find the etiology of psychiatric disorders acquired impulse. This review summarizes the new drugs for the treatment of psychiatric disorders currently under development and also presents a short list of the main biomarkers proposed for the diagnosis or the comprehension of the etiopathogeny in Psychiatry...
July 2015: Vertex: Revista Argentina de Psiquiatriá
Scott Monteith, Tasha Glenn, John Geddes, Michael Bauer
Big data are coming to the study of bipolar disorder and all of psychiatry. Data are coming from providers and payers (including EMR, imaging, insurance claims and pharmacy data), from omics (genomic, proteomic, and metabolomic data), and from patients and non-providers (data from smart phone and Internet activities, sensors and monitoring tools). Analysis of the big data will provide unprecedented opportunities for exploration, descriptive observation, hypothesis generation, and prediction, and the results of big data studies will be incorporated into clinical practice...
December 2015: International Journal of Bipolar Disorders
Birgit Böhmdorfer, Sonja Rohleder, Martin Wawruch, T J M van der Cammen, Thomas Frühwald, Christian Jagsch, Susanne Melitta Maria Janowitz, Marietta Nagano, Mirko Petrovic, Ulrike Sommeregger, Bernhard Iglseder
This article presents a list of potentially delirogenic properties of drugs that are currently of relevance to drug therapy in Europe, which was created through a Delphi process including experts from professions relevant to diagnosis and treatment of delirium. The Diagnostic and Statistical Manual of Mental Disorders 5 (DSM 5) defines delirium as a disturbance in attention, awareness and cognition that develops over a short period of time and fluctuates. Possible causes of delirium are manifold: usually delirium is considered to develop in a multifactorial way, caused by inalterable parameters, such as advanced age and pre-existing cognitive impairment and precipitated by modifiable parameters, such as the use of certain drugs or substance withdrawal...
July 2016: Zeitschrift Für Gerontologie und Geriatrie
Chadi A Calarge, Trudy L Burns, Janet A Schlechte, Babette S Zemel
OBJECTIVE: In a previous cross-sectional study, we found lower bone mass during treatment with selective serotonin reuptake inhibitors (SSRIs) and risperidone in youths. Here, we evaluate the skeletal effects of these psychotropics at follow-up. METHOD: Between April 2005 and July 2011, medically healthy 7- to 17-year-old males treated with risperidone for 6 months or more were enrolled through child psychiatry outpatient clinics and returned for follow-up 1.5 years later...
May 2015: Journal of Clinical Psychiatry
Gregory S Day, Safiya Ladak, Kevin Curley, Norman A S Farb, Paul Masiowski, Tamara Pringsheim, Michael Ritchie, Alexandra Cheung, Sandy Jansen, Linda Methot, Heather L Neville, Duane Bates, Donna Lowe, Natasha Fernandes, Alexandre Ferland, C Martin del Campo
BACKGROUND: Patients with suspected thiamine deficiency should receive treatment with parenteral thiamine to achieve the high serum thiamine levels necessary to reverse the effects of deficiency and to circumvent problems with absorption common in the medically ill. OBJECTIVE: To quantify rates of parenteral administration of thiamine across university-affiliated hospitals and to identify factors associated with higher rates of parenteral prescribing. DESIGN: Multicenter, retrospective observational study of thiamine prescriptions...
April 2015: Journal of Hospital Medicine: An Official Publication of the Society of Hospital Medicine
Louisa Degenhardt, Bianca Blanch, Natasa Gisev, Briony Larance, Sallie Pearson
INTRODUCTION: Opioid prescribing is increasing in many countries. In Australia, there is limited research on patterns of prescribing and access, or the outcomes associated with this use. The aim of this research programme is to use national dispensing data to estimate opioid use and costs, including problematic or extramedical use in the Australian population. METHODS AND ANALYSIS: In a cohort of persons dispensed at least one opioid in 2013, we will estimate monthly utilisation and costs of prescribed opioids, overall and according to individual opioid formulations and strengths...
2015: BMJ Open
Elle M Sowa, Jonathan C Fellers, Rachna S Raisinghani, Maria R Santa Cruz, Priscilla C Hidalgo, Meredith S Lee, Lady A Martinez, Adrienne E Keller, Anita H Clayton
OBJECTIVE: To investigate the value of a prescription monitoring program in identifying prescription drug misuse among patients presenting to a resident physician outpatient psychiatry clinic at an academic medical center. METHOD: Participants were 314 new patients aged 18 years or older presenting to the clinic from October 2011 to June 2012. Resident physicians completed a data collection form for each participant using information from the patient interview and from the prescription monitoring program report...
2014: Primary Care Companion to CNS Disorders
Robert L Barkin
Robert L Barkin talks to Roshaine Gunawardana, Commissioning Editor: Dr Barkin has authored over 150 publications including journals, book chapters and CD-Roms. He is a reviewer for over 30 journals, on the editorial board of nine journals and is an Associate Editor of the American Journal of Therapeutics. He received his BSc. Pharmacy degree from St Louis College of Pharmacy and Allied Science St Louis, MO, USA in 1963, an MBA in Healthcare Administration at DePaul University Chicago, IL, USA in 1976 and a doctorate in Clinical Pharmacy at Purdue University, IN, USA in 1985...
September 2012: Pain Management
Jennifer Tjia, Terry Field, Celeste Lemay, Kathleen Mazor, Michelle Pandolfi, Ann Spenard, Shih-Yieh Ho, Abir Kanaan, Jennifer Donovan, Jerry H Gurwitz, Becky Briesacher
BACKGROUND: The relationship between psychiatric consultation and antipsychotic prescribing in nursing homes (NH) is unknown. OBJECTIVE: To identify the association between psychiatric consultant groups and NH-level antipsychotic prescribing after adjustment for resident case-mix and facility characteristics. RESEARCH DESIGN AND SUBJECTS: Nested cross-sectional study of 60 NHs in a cluster randomized trial. We linked facility leadership surveys to October 2009-September 2010 Minimum Data Set, Nursing Home Compare, the US Census, and pharmacy dispensing data...
March 2014: Medical Care
Brian D McKee, Margareth Larose-Pierre, Leonard R Rappa
INTRODUCTION: The World Health Organization has estimated that as many as 450 million people worldwide have mental disorders. More than 44 million people in the United States have a mental disorder annually, estimating the annual direct costs of mental illness to exceed US$69 billion. Psychotherapeutic agents are used to treat mental illnesses and improve quality of life. The purpose of the study is to assess the knowledge and knowledge perception of community pharmacists and final-year student pharmacists regarding psychotherapeutic agents dispensed to their community of patients with mental illness...
April 2015: Journal of Pharmacy Practice
Yoko Nakazawa, Yoshiyuki Kizawa, Takahiro Hashizume, Tatsuya Morita, Tomoyo Sasahara, Mitsunori Miyashita
OBJECTIVE: This study explored how an educational intervention affects interdisciplinary palliative care consultation teams. METHODS: A pre-post questionnaire survey conducted before the intervention, as well as immediately, 3, 6 and 12 months later. The outcome measurements were behavior (four domains-17 items) and confidence (one domain-6 items). RESULTS: Of the 252 workshop participants (63 teams), 248 submitted a pre-intervention response, 240 responded immediately after, 198 after 3 months, 197 after 6 months and 184 after 12 months...
February 2014: Japanese Journal of Clinical Oncology
Katherine S McMichael, Katie Adams, Ericka L Breden Crouse
This case describes a 76-year-old African-American female with a history of depression, breast cancer, and hypothyroidism admitted to the inpatient geriatric psychiatry unit for an electroconvulsive therapy (ECT) evaluation. She had one previous episode of depression, which began after a lumpectomy in 2007. Her home medication regimen included tamoxifen 20 mg daily. This case highlights the incidence of depression in persons with breast cancer, examines the controversy of tamoxifen-induced depression, and evaluates antidepressant considerations regarding potentially efficacy-reducing cytochrome P450 2D6 drug interactions with tamoxifen...
September 2013: Consultant Pharmacist: the Journal of the American Society of Consultant Pharmacists
Lisa W Goldstone, Janet Cooley
OBJECTIVE: To create an interprofessional psychiatry advanced pharmacy practice experience (APPE) and assess the initial outcomes. DESIGN: An elective psychiatry APPE was developed in a setting of interdisciplinary practice. Preceptor responsibilities were shared between a psychiatric pharmacist and an attending psychiatrist or psychiatric nurse practitioner. Students were also given the opportunity to shadow and work with other health care professionals such as nurses, social workers, therapists, family nurse practitioners, and utilization review staff members...
August 12, 2013: American Journal of Pharmaceutical Education
Meike C Prins, A Clara Drenth-van Maanen, Rob M Kok, Paul A F Jansen
OBJECTIVE: Medication reconciliation results in fewer adverse drug events. The first step in medication reconciliation is to carry out a structured interview about medication use. It is not known whether such an interview is useful in inpatient old age psychiatry. The object of this study was to determine at admission the number of discrepancies in medication use, comparing the structured history of medication use (SHIM) procedure with the usual procedure for taking the medication history...
November 2013: CNS Drugs
I Besnard, V Auclair, G Callery, C Gabriel-Bordenave, C Roberge
BACKGROUND: Hyperprolactinemia is a frequent but neglected adverse effect observed in patients treated with antipsychotic-drugs. In this review, we summarize its physiopathogenetic mechanism, its clinical manifestations in men and women, and the way to manage it. LITERATURE FINDINGS: Prolactin is a hormone secreted by lactotroph cells in the anterior pituitary. Its synthesis and release are under the control of peptides, steroids and neurotransmitters. The main inhibitory regulation is made by dopamine, which binds dopamine receptors D2 on the membrane of lactotroph cells...
February 2014: L'Encéphale
Licia Maiocchi, Elsa Bernardi
OBJECTIVE: The aim of this clinical review was to investigate the effectiveness and safety of the practice of antipsychotic poly-pharmacy (AP) in the long-term management of hospitalised patients with insufficient response to antipsychotic monotherapy. METHOD: The databases Medline, PsycINFO, Embase and Scopus were searched. Studies were required to include inpatients with long-term, treatment-resistant schizophrenia on maintenance AP. The search was restricted to systematic review studies...
October 2013: Australasian Psychiatry: Bulletin of Royal Australian and New Zealand College of Psychiatrists
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