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https://www.readbyqxmd.com/read/28431025/1h-magnetic-resonance-spectroscopy-of-live-human-sperm
#1
S Reynolds, S J Calvert, M N Paley, A A Pacey
STUDY QUESTION: Can 1H Magnetic Resonance Spectroscopy (MRS) be used to obtain information about the molecules and metabolites in live human spermatozoa? SUMMARY ANSWER: Percoll-based density gradient centrifugation (DGC) followed by a further two washing steps, yielded enough sperm with minimal contamination (<0.01%) from seminal fluid to permit effective MRS which detected significant differences (p < 0.05) in the choline/glycerophosphocholine, lipid and lactate regions of the 1H MRS spectrum between sperm in the pellet and those from the 40/80% interface...
April 18, 2017: Molecular Human Reproduction
https://www.readbyqxmd.com/read/28430964/metalims-a-simple-open-source-laboratory-information-management-system-for-small-metagenomic-labs
#2
Cassie Elizabeth Heinle, Nicolas Paul Eugène Gaultier, Dana Miller, Rikky Wenang Purbojati, Federico M Lauro
BACKGROUND: As the cost of sequencing continues to fall, smaller groups increasingly initiate and manage larger sequencing projects and take on the complexity of data storage for high volumes of samples. This has created a need for low-cost laboratory information management systems (LIMS) that contain flexible fields to accommodate the unique nature of individual labs. Many labs do not have a dedicated IT position, so LIMS must also be easy to setup and maintain with minimal technical proficiency...
April 18, 2017: GigaScience
https://www.readbyqxmd.com/read/28429657/what-happened-first-working-memory-and-negative-emotion-tell-you-better-evidence-from-a-temporal-binding-task
#3
Chiara Mirandola, Enrico Toffalini
Emotionally arousing events may disrupt the ability to bind together different features of items to their context; this holds true both for spatial binding (i.e. remembering the locations of previously presented items) and temporal binding (i.e. remembering the order in which different items were previously presented). Nonetheless, memory for emotional events may be enhanced in certain situations. A key factor that might explain the memory-emotion relation is represented by individual differences in cognition...
April 21, 2017: Cognition & Emotion
https://www.readbyqxmd.com/read/28426986/schr%C3%A3-dinger-s-code-script-not-a-genetic-cipher-but-a-code-of-development
#4
A E Walsby, M J S Hodge
In his book What is Life? Erwin Schrödinger coined the term 'code-script', thought by some to be the first published suggestion of a hereditary code and perhaps a forerunner of the genetic code. The etymology of 'code' suggests three meanings relevant to 'code-script which we distinguish as 'cipher-code', 'word-code' and 'rule-code'. Cipher-codes and word-codes entail translation of one set of characters into another. The genetic code comprises not one but two cipher-codes: the first is the DNA 'base-pairing cipher'; the second is the 'nucleotide-amino-acid cipher', which involves the translation of DNA base sequences into amino-acid sequences...
April 17, 2017: Studies in History and Philosophy of Biological and Biomedical Sciences
https://www.readbyqxmd.com/read/28425311/later-adults-cultural-life-scripts-of-middle-and-later-adulthood
#5
Azriel Grysman, Sarah Dimakis
The cultural life script (CLS) refers to expected prototypical life events, often including life transitions overwhelmingly occurring at ages 11-30. This study outlined CLS events at ages after the majority of these events typically occur. Participants, age 38-76, nominated events they expected a person of their age to experience in the future. Participants rated each event's valence, importance, prevalence, and expected age of occurrence. Events were coded into three categories: the normative CLS for events listed by previous CLS studies, offspring's CLS for experiencing CLS events of offspring, and later adulthood CLS for other events nominated by at least 4% of participants...
April 20, 2017: Neuropsychology, Development, and Cognition. Section B, Aging, Neuropsychology and Cognition
https://www.readbyqxmd.com/read/28422618/school-nurses-on-the-front-lines-of-medicine-connecting-the-dots-scripts-for-success-in-the-evaluation-of-pediatric-rashes
#6
Robert P Olympia
Although skin rashes may not necessarily prompt a visit to the school nurse's office, a rash associated with other systemic symptoms, such as fever, headache, difficulty swallowing or breathing, weakness, or abdominal pain, may cause a child to visit your office. This article describes the initial assessment and management of skin rashes in children and adolescents and delineates reasons that may prompt the school nurse to transfer a student with a rash to a local emergency department.
May 2017: NASN School Nurse
https://www.readbyqxmd.com/read/28421027/universal-visual-features-might-be-necessary-for-fluent-reading-a-longitudinal-study-of-visual-reading-in-braille-and-cyrillic-alphabets
#7
Łukasz Bola, Dominika Radziun, Katarzyna Siuda-Krzywicka, Joanna E Sowa, Małgorzata Paplińska, Ewa Sumera, Marcin Szwed
It has been hypothesized that efficient reading is possible because all reading scripts have been matched, through cultural evolution, to the natural capabilities of the visual cortex. This matching has resulted in all scripts being made of line-junctions, such as T, X, or L. Our aim was to test a critical prediction of this hypothesis: visual reading in an atypical script that is devoid of line-junctions (such as the Braille alphabet read visually) should be much less efficient than reading in a "normal" script (e...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28420547/types-and-characteristics-of-fish-and-seafood-provisioning-scripts-used-by-rural-midlife-adults
#8
Stephanie M Bostic, Jeffery Sobal, Carole A Bisogni, Juliet M Monclova
OBJECTIVE: To examine rural New York State consumers' cognitive scripts for fish and seafood provisioning. DESIGN: A cross-sectional design with in-depth, semistructured interviews. SETTING: Three rural New York State counties. PARTICIPANTS: Adults (n = 31) with diverse fish-related experiences were purposefully recruited. PHENOMENON OF INTEREST: Scripts describing fish and seafood acquisition, preparation, and eating out...
April 15, 2017: Journal of Nutrition Education and Behavior
https://www.readbyqxmd.com/read/28419482/fmea-of-manual-and-automated-methods-for-commissioning-a-radiotherapy-treatment-planning-system
#9
Amy Wexler, Bruce Gu, Sreekrishna Goddu, Maya Mutic, Sridhar Yaddanapudi, Lindsey Olsen, Taylor Harry, Camille Noel, Todd Pawlicki, Sasa Mutic, Bin Cai
PURPOSE: To evaluate the level of risk involved in treatment planning system (TPS) commissioning using a manual test procedure, and to compare the associated process-based risk to that of an automated commissioning process (ACP) by performing an in-depth failure modes and effects analysis (FMEA). METHODS: The authors collaborated to determine the potential failure modes of the TPS commissioning process using 1) approaches involving manual data measurement, modeling, and validation tests HYPERLINK \l "Fra98" 1, HYPERLINK \l "Smi15" 2 and 2) an automated process utilizing application programming interface (API) scripting, pre-loaded and pre-modeled standard radiation beam data, digital heterogeneous phantom, and an automated commissioning test suite (ACTS)...
April 17, 2017: Medical Physics
https://www.readbyqxmd.com/read/28417100/data-for-trots-the-radiotherapy-optimisation-test-set
#10
Sebastiaan Breedveld, Ben Heijmen
The Radiotherapy Optimisation Test Set (TROTS) is an extensive set of problems originating from radiotherapy (radiation therapy) treatment planning. This dataset is created for 2 purposes: (1) to supply a large-scale dense dataset to measure performance and quality of mathematical solvers, and (2) to supply a dataset to investigate the multi-criteria optimisation and decision-making nature of the radiotherapy problem. The dataset contains 120 problems (patients), divided over 6 different treatment protocols/tumour types...
June 2017: Data in Brief
https://www.readbyqxmd.com/read/28416765/lolopicker-detecting-low-allelic-fraction-variants-from-low-quality-cancer-samples
#11
Jian Carrot-Zhang, Jacek Majewski
INTRODUCTION: Although several programs are designed to identify variants with low allelic-fraction, further improvement is needed, especially to push the detection limit of low allelic-faction variants in low-quality, "noisy" tumor samples. RESULTS: We developed LoLoPicker, an efficient tool dedicated to calling somatic variants from next-generation sequencing (NGS) data of tumor sample against the matched normal sample plus a user-defined control panel of additional normal samples...
March 12, 2017: Oncotarget
https://www.readbyqxmd.com/read/28416714/jinglebells-a-repository-of-immune-related-single-cell-rna-sequencing-datasets
#12
Hadas Ner-Gaon, Ariel Melchior, Nili Golan, Yael Ben-Haim, Tal Shay
Recent advances in single-cell RNA-sequencing (scRNA-seq) technology increase the understanding of immune differentiation and activation processes, as well as the heterogeneity of immune cell types. Although the number of available immune-related scRNA-seq datasets increases rapidly, their large size and various formats render them hard for the wider immunology community to use, and read-level data are practically inaccessible to the non-computational immunologist. To facilitate datasets reuse, we created the JingleBells repository for immune-related scRNA-seq datasets ready for analysis and visualization of reads at the single-cell level (http://jinglebells...
May 1, 2017: Journal of Immunology: Official Journal of the American Association of Immunologists
https://www.readbyqxmd.com/read/28415892/intellectual-streaking-the-value-of-teachers-exposing-minds-and-hearts
#13
Margaret Bearman, Elizabeth Molloy
As teachers we often ask learners to be vulnerable and yet present ourselves as high status, knowledgeable experts, often with pre-prepared scripts. This paper investigates the metaphoric notion of "intellectual streaking" - the nimble exposure of a teacher's thought processes, dilemmas, or failures - as a way of modeling both reflection-in-action and resilience. While there is a tension between credibility and vulnerability, both of which are necessary for trust, we argue that taking a few risks and revealing deficits in knowledge or performance can be illuminating and valuable for all parties...
April 18, 2017: Medical Teacher
https://www.readbyqxmd.com/read/28414738/barriers-and-facilitators-for-men-to-attend-prenatal-care-and-obtain-hiv-voluntary-counseling-and-testing-in-brazil
#14
Nava Yeganeh, Mariana Simon, Deborah Mindry, Karin Nielsen-Saines, Maria Cristina Chaves, Breno Santos, Marineide Melo, Brenna Mendoza, Pamina Gorbach
BACKGROUND: Providing HIV voluntary counseling and testing (VCT) to men who attend their partner's prenatal care is an intervention with potential to reduce HIV transmission to women and infants during the vulnerable period of pregnancy. Little is known about the acceptability of this intervention in global settings outside of Africa. METHODS: We conducted in-depth qualitative interviews to evaluate potential barriers and facilitators to prenatal care attendance for HIV VCT with 20 men who did and 15 men who did not attend prenatal care with their partners at Hospital Conceiçao in Porto Alegre, Brazil...
2017: PloS One
https://www.readbyqxmd.com/read/28413909/sticking-to-the-romantic-script-an-examination-of-love-life-scripts-stories-and%C3%A2-self-reports-of-normality
#15
William L Dunlop, Grace E Hanley, Tara P McCoy, Nicole Harake
Life scripts represent cultural expectations regarding the events in the prototypical life whereas life stories represent narrative constructions of the events occurring in individuals' own lives. In Study 1, we generated an outline of the love life script and a list of the self-definitional events individuals tend to associate with their own love lives. Participants were prompted to produce and rate seven important events in the prototypical love life and several significant moments from their own love lives...
April 16, 2017: Memory
https://www.readbyqxmd.com/read/28412533/print-specific-n170-involves-multiple-subcomponents-for-japanese-hiragana
#16
Tomoki Uno, Yasuko Okumura, Tetsuko Kasai
Print-specific N170 in event-related potentials is generally considered to reflect relatively automatic processing for letter strings, which is crucial for fluent reading. However, our previous studies demonstrated that print-specific N170 for transparent Japanese Hiragana script consists of at least two subcomponents under rapid stimulus presentation: an attention-related left-lateralized N170 and a bilateral N170 associated with more automatic orthographic processes (Okumura, Kasai & Murohashi, 2014, 2015)...
April 12, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28409116/prepare_taxa_charts-py-a-python-program-to-automate-generation-of-publication-ready-taxonomic-pie-chart-images-from-qiime
#17
Vijay Lakhujani, Chandan Badapanda
QIIME (Quantitative Insights Into Microbial Ecology) is one of the most popular open-source bioinformatics suite for performing metagenome, 16S rRNA amplicon and Internal Transcribed Spacer (ITS) data analysis. Although, it is very comprehensive and powerful tool, it lacks a method to provide publication ready taxonomic pie charts. The script plot_taxa_summary.py bundled with QIIME generate a html file and a folder containing taxonomic pie chart and legend as separate images. The images have randomly generated alphanumeric names...
June 2017: Genomics Data
https://www.readbyqxmd.com/read/28405988/a-study-of-salt-and-fat-consumption-pattern-in-regional-indian-diet-among-hypertensive-and-dyslipidemic-patients-script-study
#18
Dayanand Kumbla, Mala Dharmalingam, Kalpesh Dalvi, Saumitra Ray, Mahesh K Shah, Sanjay Gupta, S Sadhanandham, A K Ajmani, Sanjay Nag, Srinivas Murthy, Mohana Murugan, Abhijit Trailokya, Tushar Fegade
BACKGROUND: Cardiovascular diseases are leading cause of mortality and morbidity. There is an increasing prevalence of hypertension and dyslipidemia due to globalization and adoption of westernized dietary habits in India. These transitions are manifest in dietary patterns and health outcomes. OBJECTIVE: To study the dietary salt and fat intake among patients diagnosed with hypertension and dyslipidemia in India. METHODS: SCRIPT study was a pilot exploratory, cross-sectional, observational, descriptive, multi-center study...
December 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/28405908/how-orthographic-specific-characteristics-shape-letter-position-coding-the-case-of-thai-script
#19
Manuel Perea, Heather Winskel, Pablo Gomez
A central question for any model of visual word identification is the representation of the position at which letters are encoded (e.g., calm vs. clam). In this article, we examine whether the orthographic-specific characteristics of a writing system-namely, Thai-shape the process of letter position coding. Thai is an alphabetic script that lacks interword spaces and has an orthographic order that does not necessarily correspond to the phonological order for initial vowels. This implies that the initial letter position coding in Thai needs to be flexible enough that readers can successfully encode the letter positions of words...
April 12, 2017: Psychonomic Bulletin & Review
https://www.readbyqxmd.com/read/28403371/development-of-a-theoretical-practical-script-for-clinical-simulation
#20
Renata Paula Fabri, Alessandra Mazzo, José Carlos Amado Martins, Ariadne da Silva Fonseca, César Eduardo Pedersoli, Fernanda Berchelli Girão Miranda, Laís Fumincelli, Rui Carlos Negrão Baptista
OBJECTIVE: To develop a theoretical-practical script based on the opinion of experts to be used in simulated clinical activities. METHOD: Qualitative study through analysis of content of interviews with experts on the theme in order to develop the proposed script. Of the 24 invited experts, 12 specialists from educational institutions in Brazil and abroad participated in the study in compliance with the ethical precepts. The experts responded to questions on the characterization of their study attributes and described the items required for the development of a simulated scenario...
April 10, 2017: Revista da Escola de Enfermagem da U S P
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