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https://www.readbyqxmd.com/read/27914167/statistical-considerations-for-reporting-and-planning-heart-rate-variability-case-control-studies
#1
Daniel S Quintana
The calculation of heart rate variability (HRV) is a popular tool used to investigate differences in cardiac autonomic control between population samples. When interpreting effect sizes to quantify the magnitude of group differences, researchers typically use Cohen's guidelines of small (0.2), medium (0.5), and large (0.8) effects. However, these guidelines were originally proposed as a fallback for when the effect size distribution (ESD) was unknown. Despite the availability of effect sizes from hundreds of HRV studies, researchers still largely rely on Cohen's guidelines to interpret effect sizes and to perform power analyses to calculate required sample sizes for future research...
December 3, 2016: Psychophysiology
https://www.readbyqxmd.com/read/27914166/trauma-related-dissociation-psychological-features-and-psychophysiological-responses-to-script-driven-imagery-in-borderline-personality-disorder
#2
Dana Bichescu-Burian, Jürgen Steyer, Tilman Steinert, Benjamin Grieb, Stefan Tschöke
Defense reactions to threatening situations are vital adaptations to stress that protect organisms from injury and ensure survival. We retrospectively investigated the role of peritraumatic dissociation (PD) in the occurrence of severe psychopathology and dissociative patterns of reactions in borderline personality disorder (BPD). We recruited 28 patients with a clinical diagnosis of BPD and 15 healthy controls. The BPD group was divided according to the level of PD (low vs. high): BPD and PD (n = 15) and BPD only (n = 13)...
December 3, 2016: Psychophysiology
https://www.readbyqxmd.com/read/27907818/reactive-dissociative-experiences-in-response-to-acute-increases-in-shame-feelings
#3
Martin J Dorahy, Hadyn McKendry, Amber Scott, Kumar Yogeeswaran, Andy Martens, Donncha Hanna
Studies have not examined if a direct causal relationship exists between shame and dissociation. The current research examined whether increases in dissociation were evident following exposure to acute shame feelings induced via narrative scripts of shame-evoking situations. Following Gilbert's (1998) differentiation between external and internal shame, participants heard shame-inducing or emotionally neutral stories in conditions designed to heighten (1) external shame, (2) internal shame or (3) general shame...
November 15, 2016: Behaviour Research and Therapy
https://www.readbyqxmd.com/read/27907142/ibisa_tools-a-computational-toolkit-for-ion-binding-state-analysis-in-molecular-dynamics-trajectories-of-ion-channels
#4
Kota Kasahara, Kengo Kinoshita
Ion conduction mechanisms of ion channels are a long-standing conundrum. Although the molecular dynamics (MD) method has been extensively used to simulate ion conduction dynamics at the atomic level, analysis and interpretation of MD results are not straightforward due to complexity of the dynamics. In our previous reports, we proposed an analytical method called ion-binding state analysis to scrutinize and summarize ion conduction mechanisms by taking advantage of a variety of analytical protocols, e.g., the complex network analysis, sequence alignment, and hierarchical clustering...
2016: PloS One
https://www.readbyqxmd.com/read/27906119/degrading-traumatic-memories-with-eye-movements-a-pilot-functional-mri-study-in-ptsd
#5
Kathleen Thomaes, Iris M Engelhard, Marit Sijbrandij, Danielle C Cath, Odile A Van den Heuvel
BACKGROUND: Eye movement desensitization and reprocessing (EMDR) is an effective treatment for posttraumatic stress disorder (PTSD). During EMDR, the patient recalls traumatic memories while making eye movements (EMs). Making EMs during recall is associated with decreased vividness and emotionality of traumatic memories, but the underlying mechanism has been unclear. Recent studies support a "working-memory" (WM) theory, which states that the two tasks (recall and EMs) compete for limited capacity of WM resources...
2016: European Journal of Psychotraumatology
https://www.readbyqxmd.com/read/27900688/degradation-network-reconstruction-guided-by-metagenomic-data
#6
Rafael Bargiela, Manuel Ferrer
Network reconstruction procedures based on meta-"omics" data are an invaluable tool for inferring total and active set of reactions mediated by different members in a microbial community. Within them, network-based methods for automatic analysis of catabolic capacities in metagenomes are currently limited. Here, we describe the complete workflow, scripts, and commands allowing the automatic reconstruction of biodegradation networks using as an input meta-sequences generated by direct DNA sequencing.
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/27900355/data-taken-from-the-review-article-radiation-and-circulatory-disease-and-used-in-the-associated-meta-analysis
#7
Mark P Little
This WinZip archive 'Combined R, EpiWin & datafiles (rev 2016-9-29).zip' contains the basic data used in the meta-analysis of doi 10.1016/j.mrrev.2016.07.008 (M.P. Little, 2016) [1], complete with R (R Project version 3.2.2, 2015) [2] code used for meta-regression etc. The basic data is derived from the papers of Mulrooney et al. (D.A. Mulrooney, M.W. Yeazel, T. Kawashima, A.C. Mertens, P. Mitby, M. Stovall, S.S. Donaldson, D.M. Green, C.A. Sklar, L.L. Robison, W.M. Leisenring, 2009) [3], Cutter et al. (D.J...
December 2016: Data in Brief
https://www.readbyqxmd.com/read/27896680/what-does-a-shoulder-mri-cost-the-consumer
#8
Robert W Westermann, Cameron Schick, Christopher M Graves, Kyle R Duchman, Stuart L Weinstein
BACKGROUND: More than 100 MRIs per 1000 inhabitants are performed in the United States annually, more than almost every other country. Little is known regarding the cost of obtaining an MRI and factors associated with differences in cost. QUESTIONS/PURPOSES: By surveying all hospital-owned and independent imaging centers in Iowa, we wished to determine (1) the cost to the consumer of obtaining a noncontrast shoulder MRI, (2) the frequency and magnitude of discounts provided, and (3) factors associated with differences in cost including location (hospital-owned or independent) and Centers for Medicare & Medicaid Services designation (rural, urban, and critical access)...
November 28, 2016: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/27895005/qualitative-analysis-of-cognitive-interviews-with-school-children-a-web-based-food-intake-questionnaire
#9
Vanessa Fernandes Davies, Emil Kupek, Patricia Faria Di Pietro, Maria Alice Altenburg de Assis, Francilene Gk Vieira, Clarice Perucchi, Rafaella Mafra, Debbe Thompson, Thomas Baranowski
BACKGROUND: The use of computers to administer dietary assessment questionnaires has shown potential, particularly due to the variety of interactive features that can attract and sustain children's attention. Cognitive interviews can help researchers to gain insights into how children understand and elaborate their response processes in this type of questionnaire. OBJECTIVE: To present the cognitive interview results of children who answered the WebCAAFE, a Web-based questionnaire, to obtain an in-depth understanding of children's response processes...
November 28, 2016: JMIR Public Health and Surveillance
https://www.readbyqxmd.com/read/27894706/improved-radiologists-efficiency-and-accuracy-with-the-application-of-scripting-software-for-the-automated-reporting-of-comparison-studies
#10
Russell O Kosik, Kevin K Lee, Young S Kang, Mahesh R Patel
RATIONALE AND OBJECTIVES: The American College of Radiology reporting guidelines state that "comparison with relevant examinations and reports should be part of the radiologic consultation and report when appropriate and available." MATERIALS AND METHODS: We evaluated the use of open-source Windows scripting software for the automated retrieval of the date and time of prior studies. RESULTS AND CONCLUSION: The date and time of the comparative study are transferred automatically to the present report in a structured voice recognition dictation system with a "regular expression substitution pattern" construct...
November 25, 2016: Academic Radiology
https://www.readbyqxmd.com/read/27893904/clinical-judgment-scripts-as-a-strategy-to-foster-clinical-judgments
#11
Cheryl B Hines, Felecia G Wood
BACKGROUND: Clinical judgment encompasses how nurses use their knowledge of the patient to generate, assess, and prioritize patient care alternatives. Previous research has identified debriefing as critical to developing clinical judgment. Best practice for debriefing has yet to be identified. The purpose of this research was to investigate whether a standard debriefing script, based on Tanner's clinical judgment model, could foster clinical judgment. METHOD: Participants were senior nursing students in their final semester of study...
December 1, 2016: Journal of Nursing Education
https://www.readbyqxmd.com/read/27893777/simulating-next-generation-sequencing-datasets-from-empirical-mutation-and-sequencing-models
#12
Zachary D Stephens, Matthew E Hudson, Liudmila S Mainzer, Morgan Taschuk, Matthew R Weber, Ravishankar K Iyer
An obstacle to validating and benchmarking methods for genome analysis is that there are few reference datasets available for which the "ground truth" about the mutational landscape of the sample genome is known and fully validated. Additionally, the free and public availability of real human genome datasets is incompatible with the preservation of donor privacy. In order to better analyze and understand genomic data, we need test datasets that model all variants, reflecting known biology as well as sequencing artifacts...
2016: PloS One
https://www.readbyqxmd.com/read/27889532/characterisation-of-zbtb46-and-dc-script-znf366-in-rainbow-trout-transcription-factors-potentially-involved-in-dendritic-cell-maturation-and-activation-in-fish
#13
Jun Wang, Tiehui Wang, Ottavia Benedicenti, Catherine Collins, Kaiyu Wang, Christopher J Secombes, Jun Zou
ZBTB46 and DC-SCRIPT/ZNF366 are two zinc finger transcription factors that play important roles in regulating differentiation of dendritic cells in mammals. In this study, the ZBTB46 and DC-SCRIPT/ZNF366 homologues were identified in rainbow trout Oncorhynchus mykiss and their expression analysed in vivo and in vitro. As transcription factors, they are well conserved in sequence, genomic organisation and gene synteny. Their expression was differentially modulated by bacterial and viral PAMPs in the monocyte/macrophage like cell line RTS-11, in primary head kidney (HK) macrophages, and in HK macrophages cultured with IL-4/13A...
November 23, 2016: Developmental and Comparative Immunology
https://www.readbyqxmd.com/read/27882838/a-pragmatic-randomized-trial-comparing-telephone-based-enhanced-pharmacy-care-and-usual-care-to-support-smoking-cessation
#14
Jason Gong, Christine L Baker, Kelly H Zou, Marianna Bruno, Zhanna Jumadilova, David Lawrence, Beth Wilson, Cynthia Ewel
BACKGROUND: Smoking is the leading preventable cause of death, and tobacco control professionals continue to make progress in cessation efforts. Pharmacists can assist smokers seeking to quit by offering counseling on smoking cessation pharmacotherapies. Pragmatic randomized trials are useful for investigating practical questions about an intervention's risks, benefits, and costs in routine clinical practice. OBJECTIVE: To evaluate an enhanced pharmacy care (EPC) program involving personalized pharmacist-provided telephone counseling for supporting prescription smoking cessation medications compared with usual care (UC)...
December 2016: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/27877900/plastic-deformation-of-directionally-solidified-ingots-of-binary-and-some-ternary-mosi2-mo5si3-eutectic-composites
#15
Hirotaka Matsunoshita, Yuta Sasai, Kosuke Fujiwara, Kyosuke Kishida, Haruyuki Inui
The high-temperature mechanical properties of directionally solidified (DS) ingots of binary and some ternary MoSi2/Mo5Si3 eutectic composites with a script lamellar structure have been investigated as a function of loading axis orientation and growth rate in a temperature range from 900 to 1500°C. These DS ingots are plastically deformed above 1000 and 1100 °C when the compression axis orientations are parallel to [1[Formula: see text]0]MoSi2 (nearly parallel to the growth direction) and [001]MoSi2, respectively...
2016: Science and Technology of Advanced Materials
https://www.readbyqxmd.com/read/27875164/iterating-between-tools-to-create-and-edit-visualizations
#16
Alex Bigelow, Steven Drucker, Danyel Fisher, Miriah Meyer
A common workflow for visualization designers begins with a generative tool, like D3 or Processing, to create the initial visualization; and proceeds to a drawing tool, like Adobe Illustrator or Inkscape, for editing and cleaning. Unfortunately, this is typically a one-way process: once a visualization is exported from the generative tool into a drawing tool, it is difficult to make further, data-driven changes. In this paper, we propose a bridge model to allow designers to bring their work back from the drawing tool to re-edit in the generative tool...
January 2017: IEEE Transactions on Visualization and Computer Graphics
https://www.readbyqxmd.com/read/27874917/traitement-analg%C3%A3-sique-apr%C3%A3-s-des-interventions-en-m%C3%A3-decine-dentaire
#17
Claudio Rostetter, Heinz-Theo Lübbers, Philipp Metzler
This script gives a pragmatic advice for dentists on pain control and anti-inflammation treatment considering current literature and state of the art of analgesic treatment. Naproxen seems to be the feasible anti-inflammatory painkiller as it has a lower cardio-vascular risk profile compared to other NSAID. The higher gastrointestinal bleeding risk can be mitigated using proton-pump inhibitors. Additionally, the duration of the drug effect of about 12–15 hours allows excellent patient compliance and comfort in comparison to other NSAID...
2016: Swiss Dental Journal
https://www.readbyqxmd.com/read/27873188/imagining-the-personal-past-episodic-counterfactuals-compared-to-episodic-memories-and-episodic-future-projections
#18
Müge Özbek, Annette Bohn, Dorthe Berntsen
Episodic counterfactuals are imagined events that could have happened, but did not happen, in a person's past. Such imagined past events are important aspects of mental life, affecting emotions, decisions, and behaviors. However, studies examining their phenomenological characteristics and content have been few. Here we introduced a new method to systematically compare self-generated episodic counterfactuals to self-generated episodic memories and future projections with regard to their phenomenological characteristics (e...
November 21, 2016: Memory & Cognition
https://www.readbyqxmd.com/read/27869047/children-s-exposure-to-violent-political-conflict-stimulates-aggression-at-peers-by-increasing-emotional-distress-aggressive-script-rehearsal-and-normative-beliefs-favoring-aggression
#19
L Rowell Huesmann, Eric F Dubow, Paul Boxer, Simha F Landau, Shira Dvir Gvirsman, Khalil Shikaki
We examine the hypothesis that children's exposure to ethnic-political conflict and violence over the course of a year stimulates their increased aggression toward their own in-group peers in subsequent years. In addition, we examine what social cognitive and emotional processes mediate these effects and how these effects are moderated by gender, age, and ethnic group. To accomplish these aims, we collected three waves of data from 901 Israeli and 600 Palestinian youths (three age cohorts: 8, 11, and 14 years old) and their parents at 1-year intervals...
November 21, 2016: Development and Psychopathology
https://www.readbyqxmd.com/read/27863245/epigenetic-memory-underlies-cell-autonomous-heterogeneous-behavior-of-hematopoietic-stem-cells
#20
Vionnie W C Yu, Rushdia Z Yusuf, Toshihiko Oki, Juwell Wu, Borja Saez, Xin Wang, Colleen Cook, Ninib Baryawno, Michael J Ziller, Eunjung Lee, Hongcang Gu, Alexander Meissner, Charles P Lin, Peter V Kharchenko, David T Scadden
Stem cells determine homeostasis and repair of many tissues and are increasingly recognized as functionally heterogeneous. To define the extent of-and molecular basis for-heterogeneity, we overlaid functional, transcriptional, and epigenetic attributes of hematopoietic stem cells (HSCs) at a clonal level using endogenous fluorescent tagging. Endogenous HSC had clone-specific functional attributes over time in vivo. The intra-clonal behaviors were highly stereotypic, conserved under the stress of transplantation, inflammation, and genotoxic injury, and associated with distinctive transcriptional, DNA methylation, and chromatin accessibility patterns...
November 17, 2016: Cell
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