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https://www.readbyqxmd.com/read/28239249/attachment-to-mother-and-father-at-transition-to-middle-childhood
#1
Simona Di Folco, Serena Messina, Giulio Cesare Zavattini, Elia Psouni
The present study investigated concordance between representations of attachment to mother and attachment to father, and convergence between two narrative-based methods addressing these representations in middle childhood: the Manchester Child Attachment Story Task (MCAST) and the Secure Base Script Test (SBST). One hundred and twenty 6-year-old children were assessed by separate administrations of the MCAST for mother and father, respectively, and results showed concordance of representations of attachment to mother and attachment to father at age 6...
2017: Journal of Child and Family Studies
https://www.readbyqxmd.com/read/28238971/writing-signed-languages-what-for-what-form
#2
Donald A Grushkin
Signed languages around the world have tended to maintain an "oral," unwritten status. Despite the advantages of possessing a written form of their language, signed language communities typically resist and reject attempts to create such written forms. The present article addresses many of the arguments against written forms of signed languages, and presents the potential advantages of writing signed languages. Following a history of the development of writing in spoken as well as signed language populations, the effects of orthographic types upon literacy and biliteracy are explored...
2017: American Annals of the Deaf
https://www.readbyqxmd.com/read/28237977/accuracy-of-script-concordance-tests-in-fourth-year-medical-students
#3
Saad Nseir, Ahmed Elkalioubie, Philippe Deruelle, Dominique Lacroix, Didier Gosset
Objectives: This investigation aimed to determine the validity of script concordance test (SCT), compared with clinical-case-related short-answer management problems (SAMP), in fourth-year medical students. Methods: This retrospective study was conducted at the Medical School of Lille University. Cardiology and gynecology examinations both included 3 SCT and 2 clinical-case-related SAMP.  Final score did not include SCT results, and was out of 20 points. The passing score was ≥10/20...
February 25, 2017: International Journal of Medical Education
https://www.readbyqxmd.com/read/28236234/highly-flexible-protein-peptide-docking-using-cabs-dock
#4
Maciej Paweł Ciemny, Mateusz Kurcinski, Konrad Jakub Kozak, Andrzej Kolinski, Sebastian Kmiecik
Protein-peptide molecular docking is a difficult modeling problem. It is even more challenging when significant conformational changes that may occur during the binding process need to be predicted. In this chapter, we demonstrate the capabilities and features of the CABS-dock server for flexible protein-peptide docking. CABS-dock allows highly efficient modeling of full peptide flexibility and significant flexibility of a protein receptor. During CABS-dock docking, the peptide folding and binding process is explicitly simulated and no information about the peptide binding site or its structure is used...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28236233/application-of-the-attract-coarse-grained-docking-and-atomistic-refinement-for-predicting-peptide-protein-interactions
#5
Christina Schindler, Martin Zacharias
Peptide-protein interactions are abundant in the cell and form an important part of the interactome. Large-scale modeling of peptide-protein complexes requires a fully blind approach; i.e., simultaneously predicting the peptide-binding site and the peptide conformation to high accuracy. Here, we present one of the first fully blind peptide-protein docking protocols, pepATTRACT. It combines a coarse-grained ensemble docking search of the entire protein surface with two stages of atomistic flexible refinement...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28235396/are-psychophysiological-arousal-and-self-reported-emotional-stress-during-an-oncological-consultation-related-to-memory-of-medical-information-an-experimental-study
#6
Leonie N C Visser, Marieke S Tollenaar, Jos A Bosch, Lorenz J P van Doornen, Hanneke C J M de Haes, Ellen M A Smets
Patients forget 20-80% of information provided during medical consultations. The emotional stress often experienced by patients during consultations could be one of the mechanisms that lead to limited recall. The current experimental study therefore investigated the associations between (analog) patients' psychophysiological arousal, self-reported emotional stress and their (long term) memory of information provided by the physician. One hundred and eighty one cancer-naïve individuals acted as so-called analog patients (APs), i...
January 2017: Stress: the International Journal on the Biology of Stress
https://www.readbyqxmd.com/read/28231303/greeklex-2-a-comprehensive-lexical-database-with-part-of-speech-syllabic-phonological-and-stress-information
#7
Antonios Kyparissiadis, Walter J B van Heuven, Nicola J Pitchford, Timothy Ledgeway
Databases containing lexical properties on any given orthography are crucial for psycholinguistic research. In the last ten years, a number of lexical databases have been developed for Greek. However, these lack important part-of-speech information. Furthermore, the need for alternative procedures for calculating syllabic measurements and stress information, as well as combination of several metrics to investigate linguistic properties of the Greek language are highlighted. To address these issues, we present a new extensive lexical database of Modern Greek (GreekLex 2) with part-of-speech information for each word and accurate syllabification and orthographic information predictive of stress, as well as several measurements of word similarity and phonetic information...
2017: PloS One
https://www.readbyqxmd.com/read/28231302/bioinformatic-prediction-of-g-protein-coupled-receptor-encoding-sequences-from-the-transcriptome-of-the-foreleg-including-the-haller-s-organ-of-the-cattle-tick-rhipicephalus-australis
#8
Sergio Munoz, Felix D Guerrero, Anastasia Kellogg, Andrew M Heekin, Ming-Ying Leung
The cattle tick of Australia, Rhipicephalus australis, is a vector for microbial parasites that cause serious bovine diseases. The Haller's organ, located in the tick's forelegs, is crucial for host detection and mating. To facilitate the development of new technologies for better control of this agricultural pest, we aimed to sequence and annotate the transcriptome of the R. australis forelegs and associated tissues, including the Haller's organ. As G protein-coupled receptors (GPCRs) are an important family of eukaryotic proteins studied as pharmaceutical targets in humans, we prioritized the identification and classification of the GPCRs expressed in the foreleg tissues...
2017: PloS One
https://www.readbyqxmd.com/read/28231289/rehr-an-r-package-for-manipulating-and-analysing-electronic-health-record-data
#9
David A Springate, Rosa Parisi, Ivan Olier, David Reeves, Evangelos Kontopantelis
Research with structured Electronic Health Records (EHRs) is expanding as data becomes more accessible; analytic methods advance; and the scientific validity of such studies is increasingly accepted. However, data science methodology to enable the rapid searching/extraction, cleaning and analysis of these large, often complex, datasets is less well developed. In addition, commonly used software is inadequate, resulting in bottlenecks in research workflows and in obstacles to increased transparency and reproducibility of the research...
2017: PloS One
https://www.readbyqxmd.com/read/28230393/going-off-script-effects-of-awe-on-memory-for-script-typical-and-irrelevant-narrative-detail
#10
Alexander F Danvers, Michelle N Shiota
People often filter their experience of new events through knowledge they already have; for example, encoding new events by relying on prototypical event "scripts" at the expense of actual details. Previous research suggests that positive affect often increases this tendency. Three studies assessed whether awe-an emotion elicited by perceived vastness, and thought to promote cognitive accommodation-has the opposite effect, reducing rather than increasing reliance on event scripts. True/false questions on details of a short story about a romantic dinner were used to determine whether awe (a) reduces the tendency to impute script-consistent but false details into memory, and/or (b) promotes memory of unexpected details...
February 23, 2017: Emotion
https://www.readbyqxmd.com/read/28227960/automated-volumetry-for-unilateral-hippocampal-sclerosis-detection-in-patients-with-temporal-lobe-epilepsy
#11
Cristina Martins, Nadia Moreira da Silva, Guilherme Silva, Verena E Rozanski, Joao Paulo Silva Cunha, Cristina Martins, Nadia Moreira da Silva, Guilherme Silva, Verena E Rozanski, Joao Paulo Silva Cunha, Joao Paulo Silva Cunha, Guilherme Silva, Verena E Rozanski, Nadia Moreira da Silva, Cristina Martins
Hippocampal sclerosis (HS) is the most common cause of temporal lobe epilepsy (TLE) and can be identified in magnetic resonance imaging as hippocampal atrophy and subsequent volume loss. Detecting this kind of abnormalities through simple radiological assessment could be difficult, even for experienced radiologists. For that reason, hippocampal volumetry is generally used to support this kind of diagnosis. Manual volumetry is the traditional approach but it is time consuming and requires the physician to be familiar with neuroimaging software tools...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226051/discourses-on-short-coursetherapy-for-tuberculosis-control
#12
Fernando Mitano, Amélia Nunes Sicsú, Mônica Cristina Ribeiro Alexandre D Auria de Lima, Rarianne Carvalho Peruhype, Simone Terezinha Protti, Pedro Fredemir Palha
Objective: to analyze the meanings produced through the experiences and perceptions of healthcare professionals on the implementation of the strategy of directly observed treatment short course for tuberculosis control. Method: qualitative study carried out in Mozambique with 15 healthcare professionals. Inclusion criteriawerehaving acted in the Tuberculosis Control Program for more than one year, and exercising professional activity at the time of interview. A semi-structured script was used for data collection, and individual interviews were recorded...
January 2017: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/28224131/tashkeela-novel-corpus-of-arabic-vocalized-texts-data-for-auto-diacritization-systems
#13
Taha Zerrouki, Amar Balla
Arabic diacritics are often missed in Arabic scripts. This feature is a handicap for new learner to read َArabic, text to speech conversion systems, reading and semantic analysis of Arabic texts. The automatic diacritization systems are the best solution to handle this issue. But such automation needs resources as diactritized texts to train and evaluate such systems. In this paper, we describe our corpus of Arabic diacritized texts. This corpus is called Tashkeela. It can be used as a linguistic resource tool for natural language processing such as automatic diacritics systems, dis-ambiguity mechanism, features and data extraction...
April 2017: Data in Brief
https://www.readbyqxmd.com/read/28221710/mobile-assessment-of-heightened-skin-conductance-in-posttraumatic-stress-disorder
#14
Rebecca Hinrichs, Vasiliki Michopoulos, Sterling Winters, Alex O Rothbaum, Barbara O Rothbaum, Kerry J Ressler, Tanja Jovanovic
BACKGROUND: Increased psychophysiological reactivity is a hallmark intermediate phenotype of posttraumatic stress disorder (PTSD). Individuals with PTSD exhibit greater skin conductance (SC) responses to trauma scripts than trauma survivors without PTSD. However, trauma scripts require time for development and cannot be easily used in a single visit. Thus, there is a need for a low-cost, easy-to-use, SC recording protocol for PTSD assessment. METHODS: Using a mobile device (eSense) connected to a portable tablet computer, we assessed SC reactivity to a standard trauma interview (STI) in 63 participants recruited from Grady Memorial Hospital in Atlanta, GA, approximately 1 year after trauma exposure...
February 21, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28220731/exporting-dna-striking-a-balance-between-preventing-exploitation-and-promoting-innovation
#15
M S Pepper
DNA contains the blueprint of life. Variations in the script determine the great diversity that characterises our planet. As the analysis of large datasets derived from DNA reveals the hidden secrets of normal and abnormal structure and function as well as our ancestry, the movement of DNA between research laboratories is becoming commonplace. DNA is a resource that can be used for the benefit or to the detriment of the individuals and communities from which it is derived. But can DNA be treated as a simple commodity? How do we deal with questions such as sovereignty, discrimination and commercialisation? What underlies the current trends in attempting to regulate the movement of DNA? And how can we achieve a balance between preventing exploitation and promoting innovation? This brief overview attempts to contextualise the current landscape in South Africa with regard to the DNA that is destined to leave our shores...
January 30, 2017: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/28220428/network-reconstitution-for-quantitative-subnetwork-interaction-analysis
#16
Fumiaki Katagiri
A fundamental task in systems biology is to quantify the contributions of the systems' parts and their interactions. Here I describe a powerful concept and tool for this purpose: network reconstitution. Genotypes of an organism that represent all possible combinations of the subnetworks in question will be quantitatively phenotyped. The quantitative phenotype data is analyzed using an R script to obtain estimates for single subnetwork contributions and their interactions.
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28217873/radiosurgery-for-arteriovenous-malformations-and-the-impact-on-headaches
#17
Greg Bowden, Jonathon Cavaleri, Hideyuki Kano, Edward Monaco, Ajay Niranjan, John Flickinger, L Dade Lunsford
BACKGROUND: Arteriovenous malformations (AVMs) can underlie many diverse neurological signs and symptoms. Headaches are a common presentation that can have a significant impact on quality of life. OBJECTIVE: The authors investigated Gamma Knife(®) stereotactic radiosurgery (SRS) outcomes in patients with AVMs and associated headaches. METHODS: This retrospective study analyzed 102 patients with AVMs who underwent SRS between 1995 and 2013...
February 20, 2017: Headache
https://www.readbyqxmd.com/read/28217081/blinker-automated-extraction-of-ocular-indices-from-eeg-enabling-large-scale-analysis
#18
Kelly Kleifges, Nima Bigdely-Shamlo, Scott E Kerick, Kay A Robbins
Electroencephalography (EEG) offers a platform for studying the relationships between behavioral measures, such as blink rate and duration, with neural correlates of fatigue and attention, such as theta and alpha band power. Further, the existence of EEG studies covering a variety of subjects and tasks provides opportunities for the community to better characterize variability of these measures across tasks and subjects. We have implemented an automated pipeline (BLINKER) for extracting ocular indices such as blink rate, blink duration, and blink velocity-amplitude ratios from EEG channels, EOG channels, and/or independent components (ICs)...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28215172/the-phosphodiesterase-5-inhibitors-pde-5i-for-erectile-dysfunction-ed-a-therapeutic-challenge-for-psychiatrists
#19
Chong Siew Koon, Hatta Sidi, Jaya Kumar, Srijit Das, Ong Wan Xi, Muhammad Hizri Hatta, Cesar Alfonso
Erectile function (EF) is a prerequisite for satisfactory sexual intercourse (SI) and central to male sexual functioning. Satisfactory SI eventually leads to orgasm - a biopsychophysiological state of euphoria - leading to a sense of bliss, enjoyment and positive mental well being. For a psychiatrist, treating ED is self-propelled to harmonize these pleasurable experiences alongside with encouragement of physical wellness and sensuality. Hence, the role of PDE-5i is pivotal in the context of treating ED constitutes a therapeutic challenge...
February 15, 2017: Current Drug Targets
https://www.readbyqxmd.com/read/28210531/the-daniel-k-inouye-college-of-pharmacy-scripts-updates-on-clostridium-difficile-infection-advances-in-laboratory-testing-to-aid-diagnosis-and-treatment
#20
Louis Lteif
Clostridium difficile remains a major source of nosocomial infections and associated diarrhea. More recently, community-acquired cases are on the rise creating a concern for a serious public health threat. Appropriate infection control precautions as well as prevention and optimal management may help to avoid detrimental outbreaks. A key step is utilizing laboratory testing for quick and accurate diagnosis of potential cases. This overview article describes Clostridium difficile infection control and prevention methods and updates the most recent management strategies including a focus on the utilization and interpretation of laboratory diagnostic testing and appropriate treatment...
February 2017: Hawai'i Journal of Medicine & Public Health: a Journal of Asia Pacific Medicine & Public Health
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