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https://www.readbyqxmd.com/read/29223713/diagnostic-values-of-dce-mri-and-dsc-mri-for-differentiation-between-high-grade-and-low-grade-gliomas-a-comprehensive-meta-analysis
#1
Jianye Liang, Dexiang Liu, Peng Gao, Dong Zhang, Hanwei Chen, Changzheng Shi, Liangping Luo
RATIONALE AND OBJECTIVES: This study aimed to collect the studies on the role of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and dynamic susceptibility contrast MRI (DSC-MRI) in differentiating the grades of gliomas, and evaluate the diagnostic performances of relevant quantitative parameters in glioma grading. MATERIALS AND METHODS: We systematically searched studies on the diagnosis of gliomas with DCE-MRI or DSC-MRI in Medline, PubMed, China National Knowledge Infrastructure database, Cochrane Library, and Embase published between January 2005 and December 2016...
December 6, 2017: Academic Radiology
https://www.readbyqxmd.com/read/29223694/atraumatic-versus-conventional-lumbar-puncture-needles-a-systematic-review-and-meta-analysis
#2
Siddharth Nath, Alex Koziarz, Jetan H Badhiwala, Waleed Alhazzani, Roman Jaeschke, Sunjay Sharma, Laura Banfield, Ashkan Shoamanesh, Sheila Singh, Farshad Nassiri, Wieslaw Oczkowski, Emilie Belley-Côté, Ray Truant, Kesava Reddy, Maureen O Meade, Forough Farrokhyar, Malgorzata M Bala, Fayez Alshamsi, Mette Krag, Itziar Etxeandia-Ikobaltzeta, Regina Kunz, Osamu Nishida, Charles Matouk, Magdy Selim, Andrew Rhodes, Gregory Hawryluk, Saleh A Almenawer
BACKGROUND: Atraumatic needles have been proposed to lower complication rates after lumbar puncture. However, several surveys indicate that clinical adoption of these needles remains poor. We did a systematic review and meta-analysis to compare patient outcomes after lumbar puncture with atraumatic needles and conventional needles. METHODS: In this systematic review and meta-analysis, we independently searched 13 databases with no language restrictions from inception to Aug 15, 2017, for randomised controlled trials comparing the use of atraumatic needles and conventional needles for any lumbar puncture indication...
December 6, 2017: Lancet
https://www.readbyqxmd.com/read/29223499/a-comparison-of-standard-versus-low-dose-heparin-on-access-related-complications-after-coronary-angiography-through-radial-access-a-meta-analysis-of-randomized-controlled-trials
#3
Khagendra Dahal, Sharan Sharma, Adil Yousuf, Juyong Lee, Michael Azrin, Enrique Jimenez, Kalgi Modi, Neeraj Tandon
BACKGROUND: Transradial access (TRA) is preferred for coronary angiography (CA) or percutaneous coronary intervention due to reduced access-related complications, and mortality especially for patients with ST elevation myocardial infarction. Radial artery occlusion (RAO) is a known complication of TRA, and precludes its use as a future access site, conduit for coronary artery bypass grafting or for hemodialysis fistula placement. Although a standard dose (SD) heparin of 5000 Units is used during TRA, the risks of RAO and hematoma compared to lower dose (LD) remain unclear...
November 5, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/29223445/brucella-infection-following-total-joint-arthroplasty-a-systematic-review-of-the-literature
#4
Seung-Ju Kim, Hyun-Soo Park, Dong-Woo Lee, Jong Hun Kim
INTRODUCTION: The aim of this systematic review was to analyze the results of published treatment options in Brucella infection following total joint arthroplasty (TJA). METHODS: We performed a systematic review of the literature regarding outcomes of Brucella infection after TJA (hip and knee). We searched multiple databases for articles in the area published from 1950 to 2016. RESULTS: A total of 18 patients (12 male and 6 female; mean age 59 years) from 14 published studies were identified...
December 6, 2017: Acta Orthopaedica et Traumatologica Turcica
https://www.readbyqxmd.com/read/29223408/clinical-outcomes-to-exercise-training-in-type-1-diabetes-a-systematic-review-and-meta-analysis
#5
D Jewiss, C Ostman, N King, N A Smart
AIMS: To establish the relationship between exercise training and clinical outcomes in people with type I diabetes. METHODS: Studies were identified through a MEDLINE search strategy, Cochrane Controlled Trials Registry, CINAHL, SPORTDiscus and Science Citation Index. The search strategy included a mix of key concepts related to exercise training; type 1 diabetes; glycaemic control for trials of exercise training in people with type 1 diabetes. Searches were limited to prospective randomized or controlled trials of exercise training in humans with type 1 diabetes lasting 12 weeks or more...
December 6, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/29223013/effectiveness-of-flipped-classrooms-in-chinese-baccalaureate-nursing-education-a-meta-analysis-of-randomized-controlled-trials
#6
REVIEW
Rujun Hu, Huiming Gao, Yansheng Ye, Zhihong Ni, Ning Jiang, Xiaolian Jiang
BACKGROUND: In recent years, the flipped classroom approach has been broadly applied to nursing courses in China. However, a systematic and quantitative assessment of the outcomes of this approach has not been conducted. OBJECTIVE: The purpose of the meta-analysis is to evaluate the effectiveness of the flipped classroom pedagogy in Chinese baccalaureate nursing education. DESIGN: Meta-analysis of randomized controlled studies. DATA SOURCE: All randomized controlled trials relevant to the use of flipped classrooms in Chinese nursing education were retrieved from the following databases from their date of inception through September 23, 2017: PubMed, EMBASE, the Cochrane Central Register of Controlled Trials, CINAHL, the China National Knowledge Infrastructure, the Wanfang Database, and the Chinese Scientific Journals Database...
November 29, 2017: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/29222958/the-prevalence-and-odds-of-depression-in-patients-with-vitiligo-a-meta-analysis
#7
Guaijuan Wang, Daoqing Qiu, Hua Yang, Weibing Liu
OBJECTIVE: The objective of this study is to provide a pooled estimate of the prevalence and odds of depression in Vitiligo patients. METHODS: A systematic literature search of Medline, Embase, and Cochrane library databases was conducted. The proportions and mean questionnaire values for depression were pooled according to different evaluation methods. In controlled studies, odds ratio (OR) and standardized mean differences (SMDs) compared depression in vitiligo patients with healthy controls...
December 9, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29222914/fibrolamellar-carcinoma-in-the-carney-complex-prkar1a-loss-instead-of-the-classic-dnajb1-prkaca-fusion
#8
P Graham Rondell, Karoline Lackner, Luigi Terracciano, Yessica González-Cantú, Joseph J Maleszewski, Patricia T Greipp, Sanford M Simon, Michael S Torbenson
Fibrolamellar carcinomas are characterized by activation of protein kinase A, a kinase composed of catalytic and regulatory subunits. PRKACA encodes a catalytic subunit of protein kinase A and almost all fibrolamellar carcinomas have a heterozygous 400kb deletion that leads to the fusion of DNAJB1 and PRKACA. The resulting DNAJB1-PRKACA fusion transcript is believed to activate protein kinase A by dysregulation of the catalytic portion of the protein. In contrast, PRKAR1A encodes one of the regulatory subunits of protein kinase A...
December 9, 2017: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://www.readbyqxmd.com/read/29222889/effects-of-parenteral-%C3%AF-3-fatty-acid-supplementation-in-postoperative-gastrointestinal-cancer-on-immune-function-and-length-of-hospital-stay-a-systematic-review-and-meta-analysis
#9
Hao Bai, Zhaoping Li, Yan Meng, Yue Yu, Huanhuan Zhang, Deqiang Shen, Liyong Chen
BACKGROUND AND OBJECTIVES: Omega-3 fatty acids are widely used in nutritional support. However, whether parenteral supplementation with ω-3 fatty acids is effective for gastrointestinal cancer patients remains uncertain. This study assessed the effects of this form of parenteral nutrition on immune function and clinical outcomes in postoperative gastrointestinal cancer patients. METHODS AND STUDY DESIGN: We searched Medline, Embase, Scopus, and the reference lists of selected studies to identify randomized controlled trials that compared ω-3 fatty acids with a control, and that included immune indices, infectious complications, or length of hospital stay in the final outcomes...
2018: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29222879/prevalence-cause-and-diagnosis-of-lactose-intolerance-in-children-aged-1-5-years-a-systematic-review-of-1995-2015-literature
#10
Louise Harvey, Thomas Ludwig, Alice Qian Hou, Quak Seng Hock, Michelle Ln Tan, Seksit Osatakul, Jacques Bindels, Leilani Muhardi
BACKGROUND AND OBJECTIVES: To assess the prevalence, etiology, diagnosis of primary and secondary lactose intolerance (LI), including age of onset, among children 1-5 years of age. Suspected/perceived lactose intolerance can lead to dietary restrictions which may increase risk of future health issues. METHODS AND STUDY DESIGN: MEDLINE, CAB Abstract, and Embase were searched for articles published from January 1995-June 2015 related to lactose intolerance in young children...
2018: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29222595/-prostate-cancer-risk-calculator-mobile-applications-apps-a-systematic-review-and-scoring-using-the-validated-user-version-of-the-mobile-application-rating-scale-umars
#11
Ahmed Adam, Julian C Hellig, Marlon Perera, Damien Bolton, Nathan Lawrentschuk
PURPOSE: The use of mobile phone applications (Apps) has modernised the conventional practice of medicine. The diagnostic ability of the current Apps in prostate specific antigen monitoring, and its diagnostic ability within prostate cancer (PCa) risk calculators have not yet been appraised. We aimed to review, rate and assess the everyday functionality, and utility of all the currently available PCa risk calculator Apps. METHODS: A systematic search on iTunes, Google Play Store, Blackberry World and Windows Apps Store, was performed on 23/11/2017, using the search term 'prostate cancer risk calculator'...
December 8, 2017: World Journal of Urology
https://www.readbyqxmd.com/read/29222581/fractures-in-children-with-newly-diagnosed-hepatoblastoma
#12
Alexander J Towbin, Fernanda D C Braojos Braga, Bin Zhang, James I Geller, Greg M Tiao, Daniel J Podberesky
BACKGROUND: Hepatoblastoma is the most common primary hepatic malignancy in children. We have recently noticed an increased incidence of unsuspected fractures in children with newly diagnosed hepatoblastoma. This association has been suggested in the past, but the incidence and pathophysiology remain uncertain. OBJECTIVE: To define the incidence and imaging features of fractures in children with newly diagnosed hepatoblastoma. MATERIALS AND METHODS: We searched the oncology database and the radiology picture archiving and communication system of our large tertiary care children's hospital between January 2000 and August 2013 for all patients who presented to our institution with newly diagnosed hepatoblastoma...
December 8, 2017: Pediatric Radiology
https://www.readbyqxmd.com/read/29222056/are-bisphosphonates-efficacious-in-knee-osteoarthritis-a-meta-analysis-of-randomized-controlled-trials
#13
Elizaveta E Vaysbrot, Mikala C Osani, Mia-Cara Musetti, Timothy E McAlindon, Raveendhara R Bannuru
OBJECTIVE: To clarify the effects of bisphosphonates in knee osteoarthritis (OA) using an up-to-date meta-analysis of randomized controlled trials (RCTs). DESIGN: The protocol is registered in PROSPERO (CRD42017073449). We searched MEDLINE, EMBASE, Google Scholar, Web of Science, and Cochrane Database from inception until August 2017. We included only RCTs comparing any bisphosphonates vs. placebo in knee OA patients and reporting validated pain and function scales, radiographic progression, and adverse events outcomes...
December 5, 2017: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/29221958/a-comparison-of-the-ultrathin-orsiro-hybrid-sirolimus-eluting-stent-with-contemporary-drug-eluting-stents-a-meta-analysis-of-randomized-controlled-trials
#14
Michael J Lipinski, Brian J Forrestal, Micaela Iantorno, Rebecca Torguson, Ron Waksman
BACKGROUND: Recent studies suggest the Orsiro sirolimus-eluting stent (O-SES), which has ultrathin struts with a biodegradable sirolimus-eluting polymer coating, performed better than contemporary drug-eluting stents (DES). We performed a meta-analysis to compare clinical outcomes for all randomized controlled trials (RCTs) of O-SES vs contemporary DES. METHODS/MATERIALS: PubMed, Cochrane CENTRAL, and meeting abstracts were searched for all RCTs comparing O-SES with contemporary DES...
November 21, 2017: Cardiovascular Revascularization Medicine: Including Molecular Interventions
https://www.readbyqxmd.com/read/29221956/global-burden-of-molar-incisor-hypomineralization
#15
REVIEW
Falk Schwendicke, Karim Elhennawy, Seif Reda, Katrin Bekes, David J Manton, Joachim Krois
OBJECTIVES: We aimed to systematically review and meta-analyze the global, super-regional, regional and national prevalence of molar-incisor-hypomineralization (MIH) and to determine the numbers of prevalent and incident cases on different spatial scales. The review was registered (PROSPERO CRD42017063842). SOURCES: Five electronic databases (Medline, EMBASE, LILACS, Web of Science, Google Scholar) were searched systematically. STUDY SELECTION: Observational studies on the prevalence of MIH were included and the prevalence on different spatial scales (global, super-regional, regional, national) synthesized using random-effects meta-analyses...
December 5, 2017: Journal of Dentistry
https://www.readbyqxmd.com/read/29221955/comparison-of-external-and-internal-implant-abutment-connections-for-implant-supported-prostheses-a-systematic-review-and-meta-analysis
#16
REVIEW
Cleidiel Aparecido Araujo Lemos, Fellippo Ramos Verri, Estevam Augusto Bonfante, Joel Ferreira Santiago, Eduardo Piza Pellizzer
OBJECTIVE: The systematic review and meta-analysis aimed to answer the PICO question: "Do patients that received external connection implants show similar marginal bone loss, implant survival and complication rates as internal connection implants?". DATA: Meta-analyses of marginal bone loss, survival rates of implants and complications rates were performed for the included studies. Study eligibility criteria included (1) randomized controlled trials (RCTs) and/or prospective, (2) studies with at least 10 patients, (3) direct comparison between connection types and (4) publications in English language...
December 5, 2017: Journal of Dentistry
https://www.readbyqxmd.com/read/29221636/urothelial-neoplasms-in-pediatric-and-young-adult-patients-a-large-single-center-series
#17
James A Saltsman, Marcus M Malek, Victor E Reuter, William J Hammond, Enrico Danzer, Harry W Herr, Michael P LaQuaglia
PURPOSE: Bladder cancer is the sixth most common cancer in the United States, but is exceedingly rare in young patients, leading to a lack of accepted standards for diagnosis, treatment, and surveillance. We review our institutional experience with bladder urothelial neoplasms in pediatric and young adult patients summarizing presentation, treatment, and outcomes. METHODS: Surgical pathology records at our institution were searched for cases of urothelial neoplasms among patients ≤25 years of age treated between January 1997 and September 2016...
November 14, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29221575/clinical-outcomes-of-suprascapular-nerve-decompression-a-systematic-review
#18
REVIEW
Amit M Momaya, Adam Kwapisz, W Stephen Choate, Michael J Kissenberth, Stefan J Tolan, Keith T Lonergan, Richard J Hawkins, John M Tokish
BACKGROUND: Suprascapular neuropathy is an uncommon clinical diagnosis. Although there have been a number of case series reporting on this pathologic process, to date there has been no systematic review of these studies. This study aimed to synthesize the literature on suprascapular neuropathy with regard to clinical outcomes. The secondary objective was to detail the diagnosis and treatment of suprascapular neuropathy and any associated complications. METHODS: A systematic review was performed to identify studies that reported the results or clinical outcomes of suprascapular nerve decompression...
January 2018: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/29221278/mitral-valve-repair-versus-replacement-in-elderly-patients-a-systematic-review-and-meta-analysis
#19
Xiaoke Shang, Rong Lu, Mei Liu, Shuna Xiao, Nianguo Dong
Background: Although mitral valve repair (MVP) is generally accepted as the standard treatment for mitral valve disease, in older patients, there is increasing debate about whether MVP is superior to mitral valve replacement (MVR). We, therefore, performed a meta-analysis to compare MVP vs. MVR in the elderly population. Methods: We systematically searched PubMed, the Cochrane Library, and Scopus up to February 2017 and scrutinized the references of relevant literatures...
September 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29221149/prediction-on-the-risk-population-of-idiosyncratic-adverse-reactions-based-on-molecular-docking-with-mutant-proteins
#20
Hongbo Xie, Diheng Zeng, Xiujie Chen, Diwei Huo, Lei Liu, Denan Zhang, Qing Jin, Kehui Ke, Ming Hu
Idiosyncratic adverse drug reactions are drug reactions that occur rarely and unpredictably among the population. These reactions often occur after a drug is marketed, which means that they are strongly related to the genotype of the population. The prediction of such adverse reactions is a major challenge because of the lack of appropriate test models during the drug development process. In this study, we chose withdrawn drugs because the reasons why they were withdrawn and from which countries or regions is easily obtained...
November 10, 2017: Oncotarget
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