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https://www.readbyqxmd.com/read/29452443/gender-comparison-of-medical-student-microsurgical-skills-in-a-laboratory-model
#1
Rowena Sudario-Lumague, Yuan-Cheng Chiang, Tsan-Shiun Lin
BACKGROUND: Perceived gender-related differences in surgical skills could limit opportunities available for any aspiring surgeon. There should be more available literature and logical analysis of these observations. The objective of this study is to evaluate the microsurgical skills of male and female medical students using a standard scale in the laboratory. METHODS: This study included medical students enrolled in the Kaohsiung Chang Gung Memorial Hospital from 2002 to 2015 who were evaluated by a senior consultant for their microsurgical skills...
February 16, 2018: Journal of Reconstructive Microsurgery
https://www.readbyqxmd.com/read/29452441/assessing-the-safety-and-efficacy-of-regional-anesthesia-for-lower-extremity-microvascular-reconstruction-enhancing-recovery
#2
Qing Zhao Ruan, Shawn Diamond, Scott Zimmer, Matthew L Iorio
BACKGROUND: Perioperative pain, increased sympathetic tone, and peripheral vasospasm may be safely managed with regional nerve blockade during microvascular reconstruction in the lower extremity. Limited reports exist in this setting; therefore, we evaluated our use of peripheral nerve catheters (PNCs) during microvascular limb salvage to determine safety and efficacy for both patient and flap. METHODS: A single-institution, retrospective review of a prospectively maintained database on all patients with lower extremity free tissue transfers between 2012 and 2017 was completed...
February 16, 2018: Journal of Reconstructive Microsurgery
https://www.readbyqxmd.com/read/29452439/assessment-of-function-after-free-tissue-transfer-to-the-lower-extremity-for-chronic-wounds-using-the-lower-extremity-functional-scale
#3
Reuben A Falola, Chrisovalantis Lakhiani, Jocelyn Green, Siya Patil, Brandon Jackson, Rachel Bratescu, Ersilia Anghel, John S Steinberg, Paul J Kim, Christopher E Attinger, Karen K Evans
BACKGROUND: Free tissue transfer is one option for preservation of form and function in the native limb, in the setting of soft tissue paucity. However, the data on patient functionality after microvascular intervention is inconsistently reported. The Lower Extremity Function Scale (LEFS) measures patient-reported difficulty in carrying out 20 physical activities, on a Likert scale, the sum of which correlates with descriptive functional stages of 1-5. We assess limb functionality in this cohort of microvascular patients using the LEFS survey...
February 16, 2018: Journal of Reconstructive Microsurgery
https://www.readbyqxmd.com/read/29452438/algorithmic-approach-for-intraoperative-salvage-of-venous-congestion-in-diep-flaps
#4
Erica L Bartlett, Dmitry Zavlin, Zachery K Menn, Aldona J Spiegel
BACKGROUND: Flap congestion is a frequently described intraoperative complication during autologous breast reconstruction with abdominal perforator flaps, which, if not addressed, can lead to detrimental results such as flap failure. Here, we describe our institution's algorithm of intraoperative salvage of congested flaps and present their outcomes. METHODS: All patient charts from 2002 to 2016 of a single plastic surgeon were reviewed for patients who underwent deep inferior epigastric perforator flap breast reconstruction resulting in 602 patients and 831 flaps...
February 16, 2018: Journal of Reconstructive Microsurgery
https://www.readbyqxmd.com/read/29452425/clinical-evidence-on-dietary-supplementation-with-chia-seed-salvia-hispanica-l-a-systematic-review-and-meta-analysis
#5
Siew Li Teoh, Nai Ming Lai, Possatorn Vanichkulpitak, Vladimir Vuksan, Hoang Ho, Nathorn Chaiyakunapruk
Context: Chia seed is a popular dietary supplement, taken mainly for its high content of alpha-linolenic acid, vegetable protein, and dietary fiber, yet information about its clinical effects is lacking. Objective: This review aims to summarize the clinical evidence regarding the use of chia seed for a wide variety of health conditions. Data Sources: A number of databases, including PubMed and Embase, were searched systematically. Study Selection: Randomized controlled trials that assessed the clinical effects of chia seed consumption in human participants were included...
February 14, 2018: Nutrition Reviews
https://www.readbyqxmd.com/read/29452395/mini-extracorporeal-circulation-technology-conventional-bypass-and-prime-displacement-in-isolated-coronary-and-aortic-valve-surgery-a-propensity-matched-in-hospital-and-survival-analysis
#6
Priyadharshanan Ariyaratnam, Lindsay A Mclean, Alexander Cale, Mubarak A Chaudhry, Ajith Vijayan, Neil Richards, Martin A Jarvis, Yama Haqzad, Dumbor Ngaage, Michael E Cowen, Mahmoud Loubani
OBJECTIVES: Conventional cardiopulmonary bypass is the most commonly used means of artificial circulation in cardiac surgery. However, it suffers from the effects of haemodilution and activation of inflammatory/coagulation cascades. Prime displacement (PD) can offset haemodilution and Mini-Extracorporeal Technology (MIECT) can offset both. So far, no study has compared all of these modalities together; hence, we compared the outcomes of these 3 modalities at our institution. METHODS: This was a retrospective analysis of our cardiac surgical database...
February 14, 2018: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29452389/parity-associated-with-telomere-length-among-us-reproductive-age-women
#7
A Z Pollack, K Rivers, K A Ahrens
STUDY QUESTION: Is telomere length related to parity among a nationally representative sample of US reproductive age women? SUMMARY ANSWER: History of live birth was associated with shorter telomere length. WHAT IS KNOWN ALREADY: Shorter telomeres have been linked with a range of chronic health conditions and mortality and parity has been associated with health indicators. However, there is a lack of research on how parity relates to telomere length...
February 14, 2018: Human Reproduction
https://www.readbyqxmd.com/read/29452356/baseline-anticholinergic-burden-from-medications-predicts-incident-fatal-and-non-fatal-stroke-in-the-epic-norfolk-general-population
#8
David T Gamble, Allan B Clark, Robert N Luben, Nicholas J Wareham, Kay-Tee Khaw, Phyo K Myint
Background: Stroke is primarily a disease of older age, with a substantial impact on global mortality and morbidity. Medications with anticholinergic effects are widely used, but no studies have been conducted to examine the relationship between anticholinergic burden (ACB) and stroke in a general population. Method: The sample was drawn from the EPIC-Norfolk cohort. Baseline assessments were carried out during 1993-97 and participants were followed up until March 2016...
February 14, 2018: International Journal of Epidemiology
https://www.readbyqxmd.com/read/29452353/a-diagnostic-germ-cell-score-for-immature-testicular-tissue-at-risk-of-germ-cell-loss
#9
L Heckmann, D Langenstroth-Röwer, T Pock, J Wistuba, J-B Stukenborg, M Zitzmann, S Kliesch, S Schlatt, N Neuhaus
STUDY QUESTION: Can a systematic scoring procedure provide crucial information on the status of highly heterogeneous immature human testicular tissues in the context of cryopreservation for fertility preservation? SUMMARY ANSWER: We developed a systematic histological score as a novel diagnostic tool which differentiates the patient cohort according to the status of germ cell differentiation and number of spermatogonia (normal, diminished and absent), and which could be relevant in the fertility clinic...
February 14, 2018: Human Reproduction
https://www.readbyqxmd.com/read/29452348/non-invasive-screening-for-coronary-artery-disease-in-asymptomatic-diabetic-patients-a-systematic-review-and-meta-analysis-of-randomised-controlled-trials
#10
Olivier F Clerc, Tobias A Fuchs, Julia Stehli, Dominik C Benz, Christoph Gräni, Michael Messerli, Andreas A Giannopoulos, Ronny R Buechel, Thomas F Lüscher, Aju P Pazhenkottil, Philipp A Kaufmann, Oliver Gaemperli
It is unclear whether non-invasive screening of asymptomatic diabetic patients for coronary artery disease (CAD) may improve cardiac outcomes. Thus, we performed a systematic literature review and meta-analysis of randomised controlled trials (RCT's) on this topic. We searched appropriate RCT's in five online databases (PubMed/MEDLINE, Cochrane Library, Embase, Scopus, and Web of Science) from January 2000 to November 2017 and in 41 recent reviews. Two investigators independently extracted and assessed study data using standardised forms...
February 14, 2018: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/29452335/change-in-cardiometabolic-risk-among-blacks-whites-and-hispanics-findings-from-the-health-and-retirement-study
#11
Uchechi A Mitchell, Jennifer A Ailshire, Eileen M Crimmins
Background: Blacks experience greater multi-system physiological dysregulation, or cumulative biological risk, which is associated with poor cardiometabolic health and mortality. In this study, we assess race differences in change in risk over four years among older whites, blacks and Hispanics. Method: We examined race differences in 4-year change in individual biomarkers and a cumulative measure of risk-cardiometabolic risk (CMR)-using data for each respondent from two waves of the Health and Retirement Study's biomarker assessment (n=5,512)...
February 14, 2018: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/29452331/reproducibility-of-sub-acromial-impingement-tests-including-a-new-clinical-manoeuver
#12
Antoine Ferenczi, Agnès Ostertag, Sandra Lasbleiz, David Petrover, Alain Yelnik, Pascal Richette, Thomas Bardin, Philippe Orcel, Johann Beaudreuil
BACKGROUND: The Neer, Hawkins, and Yocum clinical tests detect sub-acromial impingement as a pathogenic process of degenerative rotator cuff disease. Their reproducibility has been little investigated. OBJECTIVES: We tested the reproducibility of the Neer, Hawkins, and Yocum clinical tests for detecting this sub-acromial impingement and also an original clinical manoeuver, the countertest with elevation with lateral rotation (CELR), which is a test of sub-acromial impingement...
February 13, 2018: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/29452307/impact-of-metabolic-syndrome-on-clinical-severity-and-long-term-prognosis-in-patients-with-myocardial-infarction-with-st-segment-elevation
#13
Lovic, Dragan B Djordjevic, Ivan S Tasic, Ivana P Nedeljkovic
AIMS: The aim of this study is to evaluate the impact of metabolic syndrome (MetS) on clinical severity and long term prognosis in patients with myocardial infarction with ST segment elevation (STEMI). METHODS: We examined 507 patients with STEMI who were admitted for primary percutaneous coronary intervention classified according to the presence of MetS using American Heart Association and the National Heart, Lung and Blood Institute definition. After applying these criteria, the patients were categorized in patients with MetS and without MetS...
February 13, 2018: Hellenic Journal of Cardiology: HJC, Hellēnikē Kardiologikē Epitheōrēsē
https://www.readbyqxmd.com/read/29452303/effect-of-biologics-on-fatigue-in-psoriatic-arthritis-a-systematic-literature-review-with-meta-analysis
#14
Thomas Reygaerts, Stéphane Mitrovic, Bruno Fautrel, Laure Gossec
OBJECTIVES: Fatigue is a significant issue in psoriatic arthritis. The objective was to assess the effect of biological disease modifying antirheumatic drugs and apremilast on fatigue in psoriatic arthritis randomised controlled trials and to compare this effect with the effect in the same trials, on pain, through a systematic literature review and meta-analysis. METHODS: A systematic literature review was performed up to January 2017 in PubMed, Embase and Cochrane databases...
February 13, 2018: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/29452298/treatment-and-outcomes-in-patients-with-igg4-related-disease-using-the-igg4-responder-index
#15
Andreu Fernández-Codina, Blanca Pinilla, Iago Pinal-Fernández, Cristina López, Guadalupe Fraile-Rodríguez, Eva Fonseca-Aizpuru, Iago Carballo, Pilar Brito-Zerón, Carlos Feijóo-Massó, Miguel López-Dupla, Maria Cinta Cid, Fernando Martínez-Valle
BACKGROUND: IgG4-related disease (IgG4-RD) is an autoimmune disease triggering an inflammatory cascade that leads to fibrosis. Outcome measures are limited and treatment options remain underexplored. OBJECTIVES: To assess the variation of the IgG4 responder index (IgG4-RI) in a cohort of IgG4-RD patients and to explore their treatments and outcomes. METHODS: We studied the clinical phenotype, severity of the disease and response to treatment in an ambispective multicenter cohort study including 14 different hospitals in Spain...
February 13, 2018: Joint, Bone, Spine: Revue du Rhumatisme
https://www.readbyqxmd.com/read/29452286/risk-factor-analysis-of-adjacent-segment-disease-requiring-surgery-after-short-lumbar-fusion-the-influence-of-rheumatoid-arthritis
#16
Jin-Sung Park, Kyu-Dong Shim, Young-Sik Song, Ye-Soo Park
BACKGROUND CONTEXT: The influence of rheumatoid arthritis (RA) on the lumbar spine has received relatively little attention compared with cervical spine, and few studies have been conducted for adjacent segment disease (ASD) after lumbar fusion in the patients with RA. PURPOSE: To determine the incidence of ASD requiring surgery (ASDrS) after short lumbar fusion and to evaluate risk factors of ASDrS, including RA. STUDY DESIGN: Retrospective cohort study PATIENT SAMPLE: This study included 479 patients who underwent lumbar spinal fusion of 3 or fewer levels, with the mean follow-up period of 51...
February 13, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29452283/posterolateral-fusion-plf-vs-transforaminal-lumbar-interbody-fusion-tlif-for-spondylolisthesis-a-systematic-review-and-meta-analysis
#17
REVIEW
Jay M Levin, Joseph E Tanenbaum, Michael P Steinmetz, Thomas E Mroz, Samuel C Overley
BACKGROUND CONTEXT: Lumbar fusion is an effective and durable treatment for symptomatic lumbar spondylolisthesis, however the current literature provides insufficient evidence to recommend an optimal surgical fusion strategy. PURPOSE: To compare the clinical outcomes, fusion rates, blood loss, and operative times between open posterolateral lumbar fusion (PLF) alone and open transforaminal lumbar interbody fusion + posterolateral fusion (TLIF) for spondylolisthesis...
February 13, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29452248/mercaptopyruvate-acts-as-endogenous-vasodilator-independently-of-3-mercaptopyruvate-sulfurtransferase-activity
#18
Emma Mitidieri, Teresa Tramontano, Danila Gurgone, Valentina Citi, Vincenzo Calderone, Vincenzo Brancaleone, Antonia Katsouda, Noriyuki Nagahara, Andreas Papapetropoulos, Giuseppe Cirino, Roberta d'Emmanuele di Villa Bianca, Raffaella Sorrentino
Hydrogen sulfide (H 2 S) is produced by the action of cystathionine-β-synthase (CBS), cystathionine-γ-lyase (CSE) or 3-mercaptopyruvate sulfurtransferase (3-MST). 3-MST converts 3-mercaptopyruvate (MPT) to H 2 S and pyruvate. H 2 S is recognized as an endogenous gaseous mediator with multiple regulatory roles in mammalian cells and organisms. In the present study we demonstrate that MPT, the endogenous substrate of 3-MST, acts also as endogenous H 2 S donor. Colorimetric, amperometric and fluorescence based assays demonstrated that MPT releases H 2 S in vitro in an enzyme-independent manner...
February 13, 2018: Nitric Oxide: Biology and Chemistry
https://www.readbyqxmd.com/read/29452242/monolithic-zirconia-crowns-in-the-aesthetic-zone-in-heavy-grinders-with-severe-tooth-wear-an-observational-case-series
#19
Torbjørn Leif Hansen, Christian Schriwer, Marit Øilo, Harald Gjengedal
OBJECTIVES: The aim of this study was to assess the clinical outcomes and patient satisfaction with monolithic zirconia crowns in patients with severe tooth wear (≥1/3 of the tooth crown) in the aesthetic zone. METHODS: The historical prospective study sample consisted of 13 patients previously treated with a total of 84 monolithic zirconia crowns. The patients had been treated in a private clinic in Bergen, Norway, in the period 2012 to 2014. All patients were men, aged 35-67 years (mean age 56...
February 13, 2018: Journal of Dentistry
https://www.readbyqxmd.com/read/29452228/a-bach2-gene-variant-is-associated-with-postoperative-recurrence-of-crohn-s-disease
#20
Michael R Laffin, Richard N Fedorak, Eytan Wine, Bryan Dicken, Karen L Madsen
BACKGROUND: Crohn's disease often requires intestinal resection, which is not considered curative. Repeat surgical intervention is necessary in over half of the patients following their initial operation. Although many genetic loci are implicated in Crohn's disease, few have been associated with post-resection recurrence. STUDY DESIGN: A cohort of Crohn's disease subjects who underwent intestinal resection was analyzed to determine genetic and clinical factors associated with post-resection recurrence...
February 13, 2018: Journal of the American College of Surgeons
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