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https://www.readbyqxmd.com/read/28655271/one-year-results-of-a-randomized-controlled-trial-on-radial-extracorporeal-shock-wave-treatment-with-predictors-of-pain-disability-and-return-to-work-in-patients-with-subacromial-pain-syndrome
#1
Elisabeth Kvalvaag, Cecilie Røe, Kaia B Engebretsen, Helene L Soberg, Niels G Juel, Erik Bautz-Holter, Leiv Sandvik, Jens I Brox
BACKGROUND: Radial extracorporeal Shock Wave Therapy (rESWT) is increasingly used to treat patients with subacromial pain syndrome despite conflicting evidence of its effectiveness. Better knowledge regarding prognostic factors may contribute to the improvement in treatment and prognosis for the patients. AIM: The first aim of this study was to evaluate the effect of rESWT in addition to supervised exercises in patients with subacromial pain syndrome after one year...
June 27, 2017: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/28655208/accuracy-in-identifying-the-source-of-subarachnoid-hemorrhage-in-the-setting-of-multiple-intracranial-aneurysms
#2
Jennifer L Orning, Sophia F Shakur, Ali Alaraj, Mandana Behbahani, Fady T Charbel, Victor A Aletich, Sepideh Amin-Hanjani
BACKGROUND: Subarachnoid hemorrhage cases with multiple cerebral aneurysms frequently demonstrate a hemorrhage pattern that does not definitively delineate the source aneurysm. In these cases, rupture site is ascertained from angiographic features of the aneurysm such as size, morphology, and location. OBJECTIVE: To examine the frequency with which such features lead to misidentification of the ruptured aneurysm. METHODS: : Records of patients who underwent surgical clipping of a ruptured aneurysm at our institution between 2004 and 2014 and had multiple aneurysms were retrospectively reviewed...
June 26, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28655184/characterization-of-a-coupled-dna-replication-and-translesion-synthesis-polymerase-supraholoenzyme-from-archaea
#3
Matthew T Cranford, Aurea M Chu, Joshua K Baguley, Robert J Bauer, Michael A Trakselis
The ability of the replisome to seamlessly coordinate both high fidelity and translesion DNA synthesis requires a means to regulate recruitment and binding of enzymes from solution. Co-occupancy of multiple DNA polymerases within the replisome has been observed primarily in bacteria and is regulated by posttranslational modifications in eukaryotes, and both cases are coordinated by the processivity clamp. Because of the heterotrimeric nature of the PCNA clamp in some archaea, there is potential to occupy and regulate specific polymerases at defined subunits...
June 26, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/28655182/longitudinal-changes-in-mean-and-pulse-pressure-and-all-cause-mortality-data-from-71-629-untreated-normotensive-individuals
#4
Athanase D Protogerou, Charalambos Vlachopoulos, Frederique Thomas, Yi Zhang, Bruno Pannier, Jacques Blacher, Michel E Safar
BACKGROUND: Blood pressure (BP) includes a steady (mean arterial pressure, MAP) and a pulsatile component that independently predict mortality. The association between longitudinal changes in central (c) pulse pressure (PP), brachial (b) PP, MAP, and incident mortality has never been investigated in this context. METHODS: Brachial MAP and PP were measured at 2 routine checkups (1st visit 1992; mean interval, 5.8 ± 2.4 years) in 71,629 individuals, age 16-95 years, none on antihypertensive drugs...
June 26, 2017: American Journal of Hypertension
https://www.readbyqxmd.com/read/28655167/identification-of-transcript-regulatory-patterns-in-cell-differentiation
#5
Arief Gusnanto, John Paul Gosling, Christopher Pope
Motivation: Studying transcript regulatory patterns in cell differentiation is critical in understanding its complex nature of the formation and function of different cell types. This is done usually by measuring gene expression at different stages of the cell differentiation. However, if the gene expression data available are only from the mature cells, we have some challenges in identifying transcript regulatory patterns that govern the cell differentiation. Results: We propose to exploit the information of the lineage of cell differentiation in terms of correlation structure between cell types...
June 24, 2017: Bioinformatics
https://www.readbyqxmd.com/read/28655165/investigation-of-natural-radioactivity-as-a-possible-driver-of-cancer-incidence-in-para%C3%A3-ba-northeastern-brazil
#6
Josineide Marques do Nascimento Santos, José Araújo Dos Santos Júnior, Ana Maria Mendoça de Albuquerque Melo, Romilton Dos Santos Amaral, Rômulo Simões Cezar Menezes, Zahily Herrero Fernández, Lino Angel Valcárcel Rojas, Jairo Dias Bezerra, Alberto Antônio da Silva, Kennedy Francys Rodrigues Damascena, Nilson Vicente da Silva Medeiros
An increase of health problems has been reported in the city of Triunfo, Paraíba, NE Brazil. This pattern has been attributed to environmental radiation since there are uranium deposits in the neighboring municipalities. The present study aimed to carry a radiometric survey in Triunfo to determine effective dose from external outdoor radiation exposure. The results were obtained through 'in situ' measurements using a gamma spectrometry system. The results ranged from 0.06 to 0.38 mSv/y, mean of 0.20 mSv/y...
June 24, 2017: Radiation Protection Dosimetry
https://www.readbyqxmd.com/read/28655164/role-of-diastolic-function-indices-in-the-risk-stratification-of-patients-with-mixed-aortic-valve-disease
#7
Alexander C Egbe, Arooj R Khan, Amber Boler, Sameh M Said, Jeffrey B Geske, William R Miranda, Emmanuel Akintoye, Heidi M Connolly, Carole A Warnes, Jae K Oh
Aims: Determine the role of diastolic function indices in pre-operative and post-operative risk stratification in patients with moderate mixed aortic valve disease (MAVD). Methods and results: A retrospective study was conducted of asymptomatic patients with moderate MAVD (a combination of moderate aortic stenosis and moderate aortic regurgitation) and an ejection fraction of 50% or more who were followed up at Mayo Clinic from 1 January 2004, to 31 December 2013...
June 23, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28655156/comparison-of-latest-generation-transfemoral-self-expandable-and-balloon-expandable-transcatheter-heart-valves
#8
Andreas Schaefer, Matthias Linder, Moritz Seiffert, Gerhard Schoen, Florian Deuschl, Niklas Schofer, Yvonne Schneeberger, Stefan Blankenberg, Hermann Reichenspurner, Ulrich Schaefer, Lenard Conradi
OBJECTIVES: We herein aimed to compare acute 30-day outcomes of latest-generation self-expandable and balloon-expandable transcatheter heart valves. METHODS: From 2012 through 2016, 104 consecutive patients (study group, 69.2% female, 81.7 ± 5.5 years, logEuroSCORE I 15.9 ± 9.3%) received transfemoral transcatheter aortic valve implantation using the Symetis ACURATE neo ® transcatheter heart valve. A control group of patients after transfemoral transcatheter aortic valve implantation with the Edwards Sapien 3™ transcatheter heart valve was retrieved from our database and matched to the study group...
June 26, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28655150/is-the-frozen-elephant-trunk-procedure-superior-to-the-conventional-elephant-trunk-procedure-for-completion-of-the-second-stage
#9
Saad Rustum, Erik Beckmann, Mathias Wilhelmi, Heike Krueger, Tim Kaufeld, Julia Umminger, Axel Haverich, Andreas Martens, Malakh Shrestha
OBJECTIVES: Our goal was to compare the results and outcomes of second-stage completion in patients who had previously undergone the elephant trunk (ET) or the frozen elephant trunk (FET) procedure for the treatment of complex aortic arch and descending aortic disease. METHODS: Between August 2001 and December 2014, 53 patients [mean age 61 ± 13 years, 64% ( n  = 34) male] underwent a second-stage completion procedure. Of these patients, 32% ( n  = 17) had a previous ET procedure and 68% ( n  = 36) a previous FET procedure as a first-stage procedure...
June 23, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28655130/comparison-of-biochemical-parameters-of-blood-and-urine-in-spinal-cord-injury-patients-and-association-with-urinary-stone-formation
#10
Gülümser Aydin, Sibel Özbudak Demir, Timur Ekiz, Murat I Nanir, Aliye Tosun
OBJECTIVE: The aim of this study was to compare the biochemical parameters of the urine and blood in SCI patients and healthy subjects. METHODS: Thirty male patients with SCI were enrolled. Biochemical features of the urine and blood of the SCI patients were compared to healthy subjects. Extracted stones were analyzed by X-ray diffraction. RESULTS: A total of 30 patients with SCI (mean age of 28.77 ± 7.3 years) and 10 healthy subjects (mean age of 27...
June 3, 2017: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/28655086/-clinical-study-of-smt-%C3%A2-video-laryngoscope-with-difficult-airway-intubation-in-emergency-department
#11
J H Yu, Y Wang
Objective: To observe the clinical feasibility and security of SMT-Ⅱ video laryngoscope in difficult airway intubation in emergency department. Methods: This study took 90 adults with difficult airway who were admitted to the rescue room of Jingxi court of Beijing Chao-Yang Hospital, Capital Medical University from January 2015 to December 2016.The patients were randomly divided into 2 groups(SMT-Ⅱ video laryngoscope group: n=45, Macintosh direct laryngoscope group: n=45), which were treated with endotracheal intubation and ventilator assisted ventilation...
July 1, 2017: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://www.readbyqxmd.com/read/28655085/-effects-of-robot-assisted-minimally-invasive-transforaminal-lumbar-interbody-fusion-and-traditional-open-surgery-in-the-treatment-of-lumbar-spondylolisthesis
#12
G Y Cui, W Tian, D He, Y G Xing, B Liu, Q Yuan, Y Q Wang, Y Q Sun
Objective: To compare the clinical effects of robot-assisted minimally invasive transforaminal lumbar interbody fusion (TLIF) and traditional open TLIF in the treatment of lumbar spondylolisthesis. Methods: A total of 41 patients with lumbar spondylolisthesis accepted surgical treatment in Department of Spinal Surgery of Beijing Jishuitan Hospital From July 2015 to April 2016 were retrospectively analyzed. There were 16 cases accepted robot-assisted minimally invasive TLIF and 25 accepted traditional open TLIF...
July 1, 2017: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://www.readbyqxmd.com/read/28655084/-therapeutic-effect-of-a-new-hybrid-technique-which-combined-laparoscopic-method-and-abdominal-repair-for-parastomal-hernia-repair
#13
W Luo, Y Wang, X Duan
Objective: To investigate the safety and effectiveness of a new hybrid technique which combined laparoscopic method and abdominal repair (Dual Lap) for parastomal herniarepair. Methods: The clinical and follow-up data of 27 cases who accepted Dual Lap procedure performed at Department of Hernia and Abdominal Wall Surgery, Wuhan Central Hospital, Tongji Medical College of Huazhong University from January 2010 to January 2015 were analyzed retrospectively. The data included 22 male patients and 5 female patients with mean age of 54 years...
July 1, 2017: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://www.readbyqxmd.com/read/28655082/-impact-of-the-2016-new-definition-and-classification-system-of-pancreatic-fistula-on-the-evaluation-of-pancreatic-fistula-after-pancreatic-surgery
#14
X L Han, J Xu, W M Wu, M H Dai, T P Zhang, Q Liao, G Chen, J C Guo, W B Wang, L Cong, Y P Zhao
Objective: To discuss the impact of updated definition and classification system of pancreatic fistula published in 2016 on the postoperative classification of pancreatic fistula. Methods: Retrospective analysis was made on patients who underwent pancreatic surgery at ward 1 in Department of General Surgery, Peking Union Medical College Hospital from January 2015 to December 2016.A total of 408 patients were included in this retrospective study, male/female was 184/224, aged from 9 to 81 years with mean age of 51...
July 1, 2017: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://www.readbyqxmd.com/read/28655066/-initial-experience-with-uniportal-video-assisted-thoracoscopic-surgery-for-anatomical-lung-resections-a-propensity-score-study-and-an-observational-assessment-of-the-learning-curve
#15
Davor Stamenovic, Antje Messerschmidt, Tillmann Jahn, Thomas Schneider
Introduction Uniportal video-assisted thoracoscopic surgery (UVATS) for anatomical lung resections has gained popularity of late. This study aimed to elucidate the impediments to implementing the uniportal access method into the daily routine of VATS lung resections. To this end, we reviewed our initial experience and evaluated our progress. Methods From January to May 2016, 24 consecutive UVATS anatomical lung resections (UVATS group) were performed by a single surgeon without any previous experience in UVATS surgery...
June 27, 2017: Zentralblatt Für Chirurgie
https://www.readbyqxmd.com/read/28655061/outcomes-in-women-with-cytology-showing-atypical-squamous-cells-of-undetermined-significance-with-vs-without-human-papillomavirus-testing
#16
Jack Cuzick, Orrin Myers, Ji-Hyun Lee, Yang Shi, Julia C Gage, William C Hunt, Michael Robertson, Cosette M Wheeler
Importance: Little is known about the long-term yield of high-grade cervical intraepithelial neoplasia (CIN) and the influence on biopsy and treatment rates of human papillomavirus (HPV) triage of cytology showing atypical squamous cells of undetermined significance (hereafter ASC-US cytology). Objective: To examine 5-year outcomes after ASC-US cytology with vs without HPV testing. Design, Setting, and Participants: In this observational study, all cervical cytology and HPV testing reports from January 1, 2007, to December 31, 2012, were obtained for women throughout New Mexico and linked to pathology reports...
June 22, 2017: JAMA Oncology
https://www.readbyqxmd.com/read/28655059/association-of-autonomic-dysfunction-with-disease-progression-and-survival-in-parkinson-disease
#17
Eduardo De Pablo-Fernandez, Carmen Tur, Tamas Revesz, Andrew J Lees, Janice L Holton, Thomas T Warner
Importance: Evidence suggests that development of autonomic dysfunction (AutD) may negatively affect disease course and survival in patients with synucleinopathies. However, the few available studies on Parkinson disease (PD) have conflicting results, comprise a small number of patients, have short follow-up periods, and lack pathologic confirmation of the diagnosis. Objective: To examine the association of time of onset of AutD with disease progression and survival in PD...
June 26, 2017: JAMA Neurology
https://www.readbyqxmd.com/read/28655058/association-of-socioeconomic-status-in-childhood-with-left-ventricular-structure-and-diastolic-function-in-adulthood-the-cardiovascular-risk-in-young-finns-study
#18
Tomi T Laitinen, Elina Puolakka, Saku Ruohonen, Costan G Magnussen, Kylie J Smith, Jorma S A Viikari, Olli J Heinonen, Noora Kartiosuo, Nina Hutri-Kähönen, Mika Kähönen, Eero Jokinen, Tomi P Laitinen, Päivi Tossavainen, Laura Pulkki-Råback, Marko Elovainio, Olli T Raitakari, Katja Pahkala, Markus Juonala
Importance: Increased left ventricular (LV) mass and diastolic dysfunction are associated with cardiovascular disease. Prospective data on effects of childhood socioeconomic status (SES) on measures of LV structure and function are lacking. Objective: To examine whether family SES in childhood was associated with LV mass and diastolic function after adjustment for conventional cardiovascular disease risk factors in childhood and adulthood. Design, Setting, and Participants: The analyses were performed in 2016 using data gathered in 1980 and 2011 within the longitudinal population-based Cardiovascular Risk in Young Finns Study...
June 26, 2017: JAMA Pediatrics
https://www.readbyqxmd.com/read/28655057/evaluating-surgeon-specific-performance-for-endoscopic-sinus-surgery
#19
Luke Rudmik, Yuan Xu, Jeremiah A Alt, Adam Deconde, Timothy L Smith, Rodney J Schlosser, Hude Quan, Zachary M Soler
Importance: Several identified factors have raised questions concerning the quality of care for endoscopic sinus surgery (ESS), including the presence of large geographic variation in the rates and extent of surgery, poorly defined indications, and lack of ESS-specific quality metrics. Combined with the risk of major complications, ESS represents a high-value target for quality improvement. Objective: To evaluate differences in surgeon-specific performance for ESS using a risk-adjusted, 5-year ESS revision rate as a quality metric...
June 22, 2017: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28655032/age-related-macular-degeneration-in-patients-with-chronic-myeloproliferative-neoplasms
#20
Marie Bak, Torben Lykke Sørensen, Esben Meulengracht Flachs, Ann-Dorthe Zwisler, Knud Juel, Henrik Frederiksen, Hans Carl Hasselbalch
Importance: It has been suggested that systemic inflammation increases the risk of age-related macular degeneration (AMD). Given that chronic immune modulation is present in patients with myeloproliferative neoplasms (MPNs), the risk of AMD in these patients may be increased. Objective: To compare the risk of AMD in patients with MPNs with the risk of AMD in matched controls from the general population. Design, Setting, and Participants: A nationwide population-based cohort study using Danish registers was conducted of all patients in Denmark who received a diagnosis between January 1, 1994, and December 31, 2013, of essential thrombocythemia, polycythemia vera, myelofibrosis, or unclassifiable MPNs...
June 22, 2017: JAMA Ophthalmology
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