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cell saver indication

Mumin Hakim, Dmitry Tumin, David P Martin, Walter Samora, Allan C Beebe, Jan E Klamar, Ashley B Hodge, Joseph D Tobias
This study assesses the effects of transfusion of autologous or allogeneic blood on cerebral and tissue oxygenation during spinal surgery. Packed red blood cell transfusions are indicated to improve oxygen delivery to tissues. There are limited data demonstrating changes in tissue oxygenation with blood administration. Tissue (deltoid) and cerebral oxygenation were monitored using near-infrared spectroscopy during spinal surgery in patients. As indicated, cell saver or allogeneic blood was administered. Tissue and cerebral oxygenation were recorded before and after transfusion...
December 2016: Journal of Extra-corporeal Technology
Nicholas Stone, Vandit Sardana, Paul Missiuna
STUDY DESIGN: Systematic Review. OBJECTIVE: To determine the indications and outcomes for intraoperative cell salvage during adolescent scoliosis correction surgery by systematically reviewing all available evidence. SUMMARY OF BACKGROUND DATA: Several blood conservation strategies exist to minimize the consequences of blood loss due to scoliosis correction surgery. The utility of intraoperative cell salvage has been contested in the literature with respect to benefits and cost...
July 7, 2016: Spine
Y M Ganushchak, E P J Körver, Y Yamamoto, P W Weerwind
A growing body of evidence indicates the superiority of minimized cardiopulmonary bypass (CPB) systems compared to conventional systems in terms of inflammatory reactions and transfusion requirements. Evident benefits of minimized CPB systems, however, do not come without consequences. Kinetic-assisted drainage, as used in these circuits, can result in severe fluctuations of venous line pressures and, consequently, fluctuation of the blood flow delivered to the patient. Furthermore, subatmospheric venous line pressures can cause gaseous microemboli...
May 2016: Perfusion
Eileen Lew, Shephali Tagore
INTRODUCTION: Intraoperative cell salvage (ICS) is an important aspect of patient blood management programmes. An ICS service was introduced at KK Women's and Children's Hospital, Singapore, from 2 May 2011 to 30 April 2013 to aid in the management of massive obstetric haemorrhage. METHODS: With support from the Ministry of Health's Healthcare Quality Improvement and Innovation Fund, a workgroup comprising obstetricians, anaesthetists and nursing staff was formed to develop training requirements, clinical guidelines and protocols for implementing ICS using the Haemonetics Cell Saver 5...
August 2015: Singapore Medical Journal
Zoltán Oláh, László Hidi, László Entz, Zoltán Szeberin
INTRODUCTION: The adequate exposure of the upper abdominal aorta and its side branches are essential for vascular reconstruction of this region. Besides the traditional transperitoneal, retroperitoneal approach or thoracolaparotomy, left medial visceral rotation (MVR) is an option to explore this hardly accessible region. We present our MVR experiences in aortic surgery. METHODS: Using median or subcostal laparotomy we mobilised the left colon, the spleen, the pancreas and performed dissection in the retroperitoneal area leaving the left kidney in place...
August 2015: Magyar Sebészet
Patricia Valda Toro, Bracha Erlanger, Julia A Beaver, Rory L Cochran, Dustin A VanDenBerg, Elizabeth Yakim, Karen Cravero, David Chu, Daniel J Zabransky, Hong Yuen Wong, Sarah Croessmann, Heather Parsons, Paula J Hurley, Josh Lauring, Ben Ho Park
OBJECTIVES: Circulating plasma DNA is being increasingly used for biomedical and clinical research as a substrate for genetic testing. However, cell lysis can occur hours after venipuncture when using standard tubes for blood collection, leading to an increase in contaminating cellular DNA that may hinder analysis of circulating plasma DNA. Cell stabilization agents can prevent cellular lysis for several days, reducing the need for immediate plasma preparation after venipuncture, thereby facilitating the ease of blood collection and sample preparation for clinical research...
October 2015: Clinical Biochemistry
Patrick D Kelly, Scott L Parker, Stephen K Mendenhall, Jesse E Bible, Priya Sivasubramaniam, David N Shau, Matthew J McGirt, Clinton J Devin
STUDY DESIGN: Mixed retrospective-prospective cohort study. OBJECTIVE: To characterize practice patterns for the use of Cell Saver at our institution, investigate its cost-effectiveness, and propose a new tool for patient selection. SUMMARY OF BACKGROUND DATA: Blood loss is an exceedingly common complication of spine surgery, and Cell Saver intraoperative cell salvage has been used to decrease reliance on allogeneic blood transfusions for blood volume replacement...
September 1, 2015: Spine
S O Kuz'menko, K S Chasovs'kyĭ
Elaborated and introduced into the practice method of the blood preservation, while correction of complex inborn heart failures (IHF) in a newborn babies, was proposed. It assumes application of system for intraoperative reinfusion of own erythrocytes with processing of residual perfusate and their reinfusion in a postperfusion period. Impact of the blood preservation on volume of a donor's blood components, hematological indices and methods of application of washed erythrocytes while correction of complex IHF in a newborn babies were presented...
January 2015: Klinichna Khirurhiia
Reza Firoozabadi, Alan Swenson, Conor Kleweno, Milton C Routt
OBJECTIVE: To determine if intraoperative autologous transfusion using a Cell Saver (CS) was routinely indicated for open reduction internal fixation (ORIF) of acetabular fractures, and if so, was there a difference between differing surgical approaches. DESIGN: Retrospective single-center cohort study. SETTING: University Level 1 trauma center. PATIENTS/PARTICIPANTS: One hundred forty-five consecutive acetabular fractures using intraoperative autologous transfusion, either treated with an anterior ilioinguinal or a posterior-based Kocher-Langenbeck approach, were compared...
August 2015: Journal of Orthopaedic Trauma
Li Du, Jianqiao Zheng, Yumin Tang
A 16-year-old male with adolescent idiopathic scoliosis was scheduled for the posterior spinal fusion (PSF) under general anesthesia. The cell saver was routinely prepared preoperatively and 400 ml of salvaged red blood cells were transfused during the surgery. After the cell salvage transfusion, the oozing of blood in surgical wounds occurred and the activated coagulation time (ACT) of the arterial blood was 999 s, considering the possibility of the residual heparin in the cell salvage, 30 mg of protamine was injected intravenously, 5 min later the ACT dropped to 125 s...
2014: International Journal of Clinical and Experimental Medicine
Dmitri van Popta, John Stephenson, Davandra Patel, Rajat Verma
BACKGROUND CONTEXT: Previous studies have shown that modern intraoperative blood-saving techniques dramatically reduce the allogeneic transfusion requirements in surgery for adolescent idiopathic scoliosis (AIS). No studies have looked at the pattern of postoperative hemoglobin (Hb) in AIS patients undergoing corrective spinal surgery and correlated this with the timing of allogeneic transfusion. PURPOSE: To describe the pattern of perioperative blood loss in instrumented surgery for AIS...
December 1, 2014: Spine Journal: Official Journal of the North American Spine Society
Javad Parvizi, Mohammad R Rasouli, Mehrad Jaberi, Guillaume Chevrollier, Scott Vizzi, Peter F Sharkey, William J Hozack
PURPOSE: It is not clear whether type of surgical approach affects the amount of blood loss in one-stage bilateral total hip arthroplasty (THA). This study therefore aims to examine if type of surgical approach can affect peri-operative blood loss and allogeneic blood transfusion in patients undergoing one-stage bilateral THA. METHODS: Records of 319 patients who underwent one-stage bilateral THA from January 2004 to June 2011 were retrospectively reviewed. Patients were divided into two groups: direct anterior (DA) approach (75 patients) and direct lateral (DL) approach (244 patients)...
December 2013: International Orthopaedics
R Schumann, S Mandell, M D Michaels, J Klinck, A Walia
BACKGROUND: Volume resuscitation and use of vasoactive medications during liver transplantation has not been systematically assessed. Furthermore, the anesthesiologist's role for intraoperative oversight of technologies such as renal replacement therapy and procedures such as venovenous bypass is poorly defined, and it is unclear if the center's annual transplant frequency affects these practices. METHODS: We conducted a database analysis of the Liver Transplant Anesthesia Consortium survey 202 that addresses these questions...
July 2013: Transplantation Proceedings
Zachary L Gordon, Jochen P Son-Hing, Connie Poe-Kochert, George H Thompson
BACKGROUND: Reducing perioperative blood loss and transfusion requirements is important in the operative treatment of idiopathic scoliosis. This can be achieved with special frames, cell saver systems, pharmacologic aspects, and other techniques. Recently there has been interest in bipolar sealer devices as an adjunct to traditional monopolar electrocautery. However, there is limited information on this device in pediatric spinal deformity surgery. We reviewed our experience with this device in a setting of a standard institutional operative carepath...
October 2013: Journal of Pediatric Orthopedics
Jonathan H Waters, Mark Yazer, Yi-Fan Chen, John Kloke
BACKGROUND: Intraoperative blood salvage (IBS) is a technique that is frequently used in major blood loss surgery. Classically, it is avoided during cancer surgery where a fear exists of entraining cancer cells into the shed blood. In this study, all reports of this practice were collected to determine if this fear is warranted. STUDY DESIGN AND METHODS: A literature search was performed including the search phrases "blood salvage,"intraoperative blood salvage,"cell salvage,"cell saver,"cell saving,"autotransfusion," and "autologous transfusion...
October 2012: Transfusion
Stefan Endres, Martin Heinz, Axel Wilke
BACKGROUND: Degenerative spinal stenosis and instability requiring multilevel spine surgery has been associated with large blood losses. Factors that affect perioperative blood loss include time of surgery, surgical procedure, patient height, combined anterior/posterior approaches, number of levels fused, blood salvage techniques, and the use of anti-fibrinolytic medications. This study was done to evaluate the efficacy of tranexamic acid in reducing blood loss in spine surgery. METHODS: This retrospective case control study includes 97 patients who had to undergo surgery because of degenerative lumbar spinal stenosis and instability...
2011: BMC Surgery
Irina Lasarzik, Jan Cordier, Dirk Peetz, Philipp von Landenberg, Christian Werner, Kristin Engelhard, Serge C Thal
BACKGROUND: Autologous blood transfusion (ABT), for example, by means of cell saver equipment, is used to reduce the need for allogenic blood transfusion in patients with high perioperative blood loss. This study investigated the effect of blood/extracorporal surface interaction during withdrawal and retransfusion of shed autologous blood on cerebral inflammation in rats. Rats subjected to hypotension with cerebral ischemia served as positive controls. METHODS: Eighty-eight male Sprague-Dawley rats were anesthetized with sevoflurane, instrumented, and randomly assigned to the following groups: sham-operation (SHAM), autologous blood withdrawal/transfusion only (ABT), or bilateral carotid artery occlusion and autologous blood withdrawal/transfusion (BCAO/ABT)...
July 2011: Journal of Neurosurgical Anesthesiology
Luis D Pacheco, Alfredo F Gei
Obstetric hemorrhage is one of the most common causes of maternal morbidity and mortality worldwide, and abnormal placentation, including placenta accreta, is currently the most common indication for peripartum hysterectomy. Prenatal identification of these cases and early referral to centers with the capability to manage them will likely result in improved outcomes. Interventions that may limit transfusion requirements include normovolemic hemodilution, selective embolization of pelvic vessels by interventional radiology, conservative management of accretism in a few selected cases, and the use of the cell saver intraoperatively...
June 2011: Obstetrics and Gynecology Clinics of North America
Gemma Yarham, Ann Clements, Martin Oliver, Christopher Morris, Tom Cumberland, Megan Bryan, Sasa Jekler, Kathy Johns, John Mulholland
INTRODUCTION: Donor blood supplies are diminishing, becoming more costly and these transfusions lead to higher mortality in cardiac patients. The transfusion risks and the literature highlight the need for an alternative similar to cell salvage to be routinely considered. The Xtra is the first cell saver to be launched since 2001 and will undoubtedly initiate evolution towards the 'next generation' of cell savers. It is also the first to be launched in a new era where the demand for electronic perfusion data management (EPDM) has grown...
July 2011: Perfusion
D R Bikmullina, Iu V Borisov, M S Zaĭnulina
A clinic, laboratory and Doppler ultrasound study including women with a high risk of coagulopathic bleeding in delivery was carried out. When indicated, a coagulopathic bleeding prophylaxis was performed with administration of the tranexamic acid or with autotransfusion of the pre-stored fresh frozen plasma. Also, a reinfusion of washed red blood cells was performed using a Cell Saver. It was found out that the infusion of tranexamic acid during surgical delivery in severe gestosis patients has significantly reduced the intraoperative blood loss and prevented the coagulopathic bleeding...
November 2010: Anesteziologiia i Reanimatologiia
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