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https://www.readbyqxmd.com/read/28106373/preparation-of-reduced-graphene-oxide-zno-hybrid-cathode-interlayer-using-in-situ-thermal-reduction-annealing-for-interconnecting-nanostructure-and-its-effect-on-organic-solar-cell
#1
Ding Zheng, Wei Huang, Pu Fan, Yifan Zheng, Jiang Huang, Junsheng Yu
A novel hybrid cathode interlayer (CIL) consisting of reduced graphene oxide and zinc oxide (ZnO) is realized in the inverted organic solar cells (OSCs). Dual-nozzle spray coating system and facile one step in-situ thermal reduction/annealing (ITR/ITA) method are introduced to precisely control the components of the CIL, assemble ZnO with graphene oxide, and reduce graphene oxide into in-situ thermal reduced graphene oxide (IT-RGO), simultaneously. The ZnO:IT-RGO hybrid CIL shows high electric conductivity, interconnecting nanostructure and matched energy level, which leads to a significant enhancement in the power conversion efficiency from 6...
January 20, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28105171/collagen-gel-droplet-embedded-culture-drug-sensitivity-testing-in-squamous-cell-carcinoma-cell-lines-derived-from-human-oral-cancers-optimal-contact-concentrations-of-cisplatin-and-fluorouracil
#2
Kaname Sakuma, Akira Tanaka, Izumi Mataga
The collagen gel droplet-embedded culture drug sensitivity test (CD-DST) is an anticancer drug sensitivity test that uses a method of three-dimensional culture of extremely small samples, and it is suited to primary cultures of human cancer cells. It is a useful method for oral squamous cell carcinoma (OSCC), in which the cancer tissues available for testing are limited. However, since the optimal contact concentrations of anticancer drugs have yet to be established in OSCC, CD-DST for detecting drug sensitivities of OSCC is currently performed by applying the optimal contact concentrations for stomach cancer...
December 2016: Oncology Letters
https://www.readbyqxmd.com/read/28104901/reliability-of-a-clinical-reasoning-viva-assessment-in-an-australian-pre-professional-osteopathy-program-based-on-generalizability-theory
#3
Brett Vaughan, Paul Orrock, Sandra Grace
Clinical reasoning is situation-dependent and case-specific therefore assessment across different patient presentations is warranted. The present study aims to know if reliability of multi-station case-based viva assessment of clinical reasoning in an Australian pre-registration osteopathy program based on generalizability theory. Students (year 4 and 5) and examiners were recruited from the osteopathy program at Southern Cross University, Lismore, Australia. The study took place on a single day in the student teaching clinic...
January 20, 2017: Journal of Educational Evaluation for Health Professions
https://www.readbyqxmd.com/read/28098975/development-of-spiro-cyclopenta-1-2-b-5-4-b-dithiophene-4-9-fluorene-based-a-%C3%AF-d-%C3%AF-a-small-molecules-with-different-acceptor-units-for-efficient-organic-solar-cells
#4
Wengong Wang, Ping Shen, Xinning Dong, Chao Weng, Guo Wang, Haijun Bin, Jing Zhang, Zhi-Guo Zhang, Yongfang Li
Three acceptor-π-donor-π-acceptor (A-π-D-π-A) small molecules (STFYT, STFRDN, and STFRCN) with spiro[cyclopenta[1,2-b:5,4-b']dithiophene-4,9'-fluorene] (STF) as the central donor unit, terthiophene as the π-conjugated bridge, indenedione, 3-ethylrhodanine, or 2-(1,1-dicyanomethylene)rhodanine as the acceptor unit are designed, synthesized and characterized as electron donor materials in solution-processing organic solar cells (OSCs). The effects of the spiro STF-based central core and different acceptors on the molecular configuration, absorption properties, electronic energy levels, carrier transport properties, the morphology of active layers, and photovoltaic properties are investigated in detail...
January 18, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28094830/molecular-electron-acceptors-for-efficient-fullerene-free-organic-solar-cells
#5
Shuixing Li, Zhongqiang Zhang, Minmin Shi, Chang-Zhi Li, Hongzheng Chen
Nowadays, organic solar cells (OSCs) with efficiencies over 10% have been achieved through the elaborate design of electron donors and fullerene acceptors. However, the drawbacks of fullerene acceptors, like poor absorption, limited chemical and energetic tunabilities, high-cost purification and morphological instability, have become the bottlenecks for the further improvement of OSCs. To overcome the mentioned shortages from fullerene, research studies on non-fullerene electron acceptors have boomed. To date, the highest efficiency of fullerene-free OSCs has been pushed to be 12%, which surpasses that of fullerene-based OSCs...
January 17, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28090108/a-process-for-curricular-improvement-based-on-evaluation-of-student-performance-on-milestone-examinations
#6
Marcy Hernick, Ann C Hylton, Michael Justice
Objective. To identify and address areas for curricular improvement by evaluating student achievement of expected learning outcomes and competencies on annual milestone examinations. Design. Students were tested each professional year with a comprehensive milestone examination designed to evaluate student achievement of learning outcomes and professional competencies using a combination of multiple-choice questions, standardized patient assessments (SPAs), and objective structured clinical examination (OSCE) questions...
November 25, 2016: American Journal of Pharmaceutical Education
https://www.readbyqxmd.com/read/28090107/developing-a-framework-for-objective-structured-clinical-examinations-using-the-nominal-group-technique
#7
Safeera Y Hussainy, Matthew F Crum, Paul J White, Ian Larson, Daniel T Malone, David T Manallack, Joseph A Nicolazzo, Jennifer McDowell, Angelina S Lim, Carl M Kirkpatrick
Objective. To use the nominal group technique to develop a framework to improve existing and develop new objective structured clinical examinations (OSCEs) within a four-year bachelor of pharmacy course. Design. Using the nominal group technique, a unique method of group interview that combines qualitative and quantitative data collection, focus groups were conducted with faculty members, practicing pharmacists, and undergraduate pharmacy students. Five draft OSCEs frameworks were suggested and participants were asked to generate new framework ideas...
November 25, 2016: American Journal of Pharmaceutical Education
https://www.readbyqxmd.com/read/28086879/validity-evidence-for-two-objective-structured-clinical-examination-stations-to-evaluate-core-skills-of-the-shoulder-and-knee-assessment
#8
Michael J Battistone, Andrea M Barker, J Peter Beck, Robert Z Tashjian, Grant W Cannon
BACKGROUND: We developed two objective structured clinical examinations (OSCEs) to educate and evaluate trainees in the evaluation and management of shoulder and knee pain. Our objective was to examine the evidence for validity of these OSCEs. METHODS: A multidisciplinary team of content experts developed checklists of exam maneuvers and criteria to guide rater observations. Content was proposed by faculty, supplemented by literature review, and finalized using a Delphi process...
January 13, 2017: BMC Medical Education
https://www.readbyqxmd.com/read/28077779/embryonic-exposure-to-tcdd-impacts-osteogenesis-of-the-axial-skeleton-in-japanese-medaka-oryzias-latipes
#9
AtLee T D Watson, Antonio Planchart, Carolyn J Mattingly, Christoph Winkler, David M Reif, Seth W Kullman
Recent studies from mammalian, fish, and in vitro models have identified bone and cartilage development as sensitive targets for dioxins and other aryl hydrocarbon receptor ligands. In this study, we assess how embryonic 2,3,7,8-tetrachlorochlorodibenzo-p-dioxin (TCDD) exposure impacts axial osteogenesis in Japanese medaka (Oryzias latipes), a vertebrate model of human bone development. Embryos from inbred wild-type Orange-red Hd-dR and 3 transgenic medaka lines (twist:EGFP, osx/sp7:mCherry, col10a1:nlGFP) were exposed to 0...
November 15, 2016: Toxicological Sciences: An Official Journal of the Society of Toxicology
https://www.readbyqxmd.com/read/28074720/-registration-of-assessments-in-orthopaedic-residents-portfolios-is-falling-short
#10
S N van Vendeloo, P L P Brand, B J Burger, R G H H Nelissen, S K Bulstra, C C P M Verheyen
OBJECTIVE: To evaluate of the number of registered competency assessments in the portfolios of orthopaedic residents in the Netherlands, for whom a competency-based training programme is mandatory. DESIGN: National cohort study. METHOD: We collected data regarding the registered assessments of all orthopaedic residents who finished their training between 2012-2015. We determined the number of registered assessments of 'standard orthopaedic treatments' (evaluating residents' competency in 70 different orthopaedic treatments), objective structured clinical skills evaluations (OSCEs), critically appraised topics (CATs), and 360 degree feedback appraisals...
2017: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/28071700/temperature-dependent-schottky-barrier-in-high-performance-organic-solar-cells
#11
Hui Li, Dan He, Qing Zhou, Peng Mao, Jiamin Cao, Liming Ding, Jizheng Wang
Organic solar cells (OSCs) have attracted great attention in the past 30 years, and the power conversion efficiency (PCE) now reaches around 10%, largely owning to the rapid material developments. Meanwhile with the progress in the device performance, more and more interests are turning to understanding the fundamental physics inside the OSCs. In the conventional bulk-heterojunction architecture, only recently it is realized that the blend/cathode Schottky junction serves as the fundamental diode for the photovoltaic function...
January 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28063937/cerebrospinal-fluid-metabolomic-profiling-in-tuberculous-and-viral-meningitis-screening-potential-markers-for-differential-diagnosis
#12
Zihui Li, Boping Du, Jing Li, Jinli Zhang, Xiaojing Zheng, Hongyan Jia, Aiying Xing, Qi Sun, Fei Liu, Zongde Zhang
BACKGROUND: Tuberculous meningitis (TBM) is the most severe and frequent form of central nervous system tuberculosis. The current lack of efficient diagnostic tests makes it difficult to differentiate TBM from other common types of meningitis, especially viral meningitis (VM). Metabolomics is an important tool to identify disease-specific biomarkers. However, little metabolomic information is available on adult TBM. METHODS: We used (1)H nuclear magnetic resonance-based metabolomics to investigate the metabolic features of the CSF from 18 TBM and 20 VM patients...
January 4, 2017: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/28063335/-1-h-nmr-based-metabolomics-study-of-liver-damage-induced-by-ginkgolic-acid-15-1-in-mice
#13
Lei Jiang, Zhi-Hong Si, Ming-Hui Li, He Zhao, Yong-Hong Fu, Yue-Xiao Xing, Wei Hong, Ling-Yu Ruan, Pu-Min Li, Jun-Song Wang
Ginkgolic acid (15:1) is a major toxic component in extracts obtained from Ginkgo biloba (EGb) that has allergic and genotoxic effects. This study is the first to explore the hepatotoxicity of ginkgolic acid (15:1) using a NMR (nuclear magnetic resonance)-based metabolomics approach in combination with biochemistry assays. Mice were orally administered two doses of ginkgolic acid (15:1), and mouse livers and serum were then collected for NMR recordings and biochemical assays. The levels of activity of alanine aminotransferase (ALT) and glutamic aspartate transaminase (AST) observed in the ginkgolic acid (15:1)-treated mice suggested that it had induced severe liver damage...
December 29, 2016: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/28056969/voluntary-attendance-of-small-group-brainstorming-tutoring-courses-intensify-new-clerk-s-excellence-in-clinical-care-a-pilot-study
#14
Ling-Yu Yang, Chia-Chang Huang, Hui-Chi Hsu, Ying-Ying Yang, Ching-Chi Chang, Chiao-Lin Chuang, Wei-Shin Lee, Jen-Feng Liang, Hao Min Cheng, Chin-Chou Huang, Fa-Yauh Lee, Shung-Tai Ho, Ralph Kirby
BACKGROUND: Clerkship provides a unique way of transferring the knowledge and skills gathered during medical school's curriculum into real-ward clinical care environment. The annual program evaluation has indicated that the training of clerks in diagnostic and clinical reasoning skills needed to be enhanced. Recently, "clinical excellence" program have been promoted in our institution to augment the excellence in clinical care of new clerks. Current study aims to evaluate whether this pilot program improve the "clinical excellence" of new clerks...
January 6, 2017: BMC Medical Education
https://www.readbyqxmd.com/read/28052682/prognostic-significance-of-mapk-topo-ii%C3%AE-and-e-cadherin-immunoexpression-in-ovarian-serous-carcinomas
#15
D Sundov, B Petric Mise, I Mrklic, B Bacic, E Vrdoljak, S Tomis
Ovarian cancer accounts for only 3% of all cancers in women but is the most lethal gynaecologic malignancy. Low-grade and high-grade ovarian serous carcinomas (OSCs) represent two different diseases with different prognosis, approaches to detection and treatment. We assessed correlation between, MAPK, topoIIα, E-cadherin immunoexpression and clinicopathological features with overall survival (OS) in OSCs. The study included 81 patients undergoing surgery between January 1995 and December 2005.Formalin fixed paraffin embedded tumour sections were reviewed and examined immunohistochemically using antibodies against MAPK, topoIIα and E-cadherin...
January 5, 2017: Neoplasma
https://www.readbyqxmd.com/read/28035056/factors-associated-with-medical-student-test-anxiety-in-objective-structured-clinical-examinations-a-preliminary-study
#16
Kyong-Jee Kim
Objectives: To investigate attributes of medical students associated with their test anxiety on Objective Structured Clinical Examinations (OSCEs). Methods: A cross-sectional study using a self-administered questionnaire was conducted of all Year 3 and 4 students at a private medical school in South Korea in 2014. This 53-item questionnaire consisted of factors pertaining to test anxiety on the OSCE identified from a review of relevant literature, which included students' motivational beliefs and achievement emotions, perceived values of the OSCE, and attitude and orientation towards patients...
December 29, 2016: International Journal of Medical Education
https://www.readbyqxmd.com/read/28032372/microrna-210-is-increased-and-it-is-required-for-dedifferentiation-of-osteosarcoma-cell-line
#17
Haixia Zhang, Qing Mai, Juntao Chen
Osteosarcoma (OS) is the most common malignant bone tumor and is prevalent in adolescents. In clinical studies, miR-210 has been reported to be tightly correlated to the poor prognosis of OS. Nevertheless, its roles in OS have not been fully elucidated. In view of the central role played by OS stem cells (OSCs) in the malignant progression of OS, this study investigated the influence of miR-210 on the formation of OSCs. Our previous findings suggested that the microenvironment of bone, abundant TGF-β1 and hypoxia, could induce OS cells to dedifferentiate into OSCs...
December 29, 2016: Cell Biology International
https://www.readbyqxmd.com/read/28028909/regulation-of-injury-induced-ovarian-regeneration-by-activation-of-oogonial-stem-cells
#18
Piril Erler, Alexandra Sweeney, James R Monaghan
Some animals have the ability to generate large numbers of oocytes throughout life. This raises the question whether persistent adult germline stem cell populations drive continuous oogenesis and whether they are capable of mounting a regenerative response after injury. Here we demonstrate the presence of adult oogonial stem cells (OSCs) in the adult axolotl salamander ovary and show that ovarian injury induces OSC activation and functional regeneration of the ovaries to reproductive capability. Cells that have morphological similarities to germ cells were identified in the developing and adult ovaries via histological analysis...
January 2017: Stem Cells
https://www.readbyqxmd.com/read/28024435/an-osce-with-very-limited-resources-is-it-possible
#19
Giancarlo Lucchetti, Oscarina S Ezequiel, Alessandra L G Lucchetti
No abstract text is available yet for this article.
December 26, 2016: Medical Teacher
https://www.readbyqxmd.com/read/28005984/knowledge-and-skills-of-healthcare-providers-in-sub-saharan-africa-and-asia-before-and-after-competency-based-training-in-emergency-obstetric-and-early-newborn-care
#20
Charles A Ameh, Robert Kerr, Barbara Madaj, Mselenge Mdegela, Terry Kana, Susan Jones, Jaki Lambert, Fiona Dickinson, Sarah White, Nynke van den Broek
BACKGROUND: Healthcare provider training in Emergency Obstetric and Newborn Care (EmOC&NC) is a component of 65% of intervention programs aimed at reducing maternal and newborn mortality and morbidity. It is important to evaluate the effectiveness of this. METHODS: We evaluated knowledge and skills among 5,939 healthcare providers before and after 3-5 days 'skills and drills' training in emergency obstetric and newborn care (EmOC&NC) conducted in 7 sub-Saharan Africa countries (Ghana, Kenya, Malawi, Nigeria, Sierra Leone, Tanzania, Zimbabwe) and 2 Asian countries (Bangladesh, Pakistan)...
2016: PloS One
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