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https://www.readbyqxmd.com/read/28915153/associations-of-early-opioid-use-with-patient-reported-outcomes-and-healthcare-utilization-among-older-adults-with-low-back-pain
#1
Laura S Gold, Ryan N Hansen, Andrew L Avins, Zoya Bauer, Bryan A Comstock, Richard A Deyo, Patrick J Heagerty, Sean D Rundell, Pradeep Suri, Judith A Turner, Jeffrey G Jarvik
OBJECTIVES: To compare outcomes and healthcare utilization of older patients who did versus did not fill opioid prescriptions within 90 days of initiating care for low back pain. MATERIALS AND METHODS: For patients ≥65 years with new back pain visits, we used propensity scores to match those who filled no opioid prescriptions to those who filled ≥2 opioid prescriptions within 90 days (and the first opioid prescription within 30 d) of the index visit. Over 24 months, we examined patient-reported outcomes, healthcare utilization, and subsequent opioid prescription fills...
September 14, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28914967/chemotherapy-response-score-is-a-useful-histological-predictor-of-prognosis-in-high-grade-serous-carcinoma
#2
Authors Priya Singh, Vikrant Kaushal, Bhavana Rai, Arvind Rajwanshi, Nalini Gupta, Pranab Dey, Rashi Garg, Manish Rohilla, Vanita Suri, Sushmita Ghoshal, Radhika Srinivasan
AIM: High grade serous carcinoma (HGSC) is the most common tubal/ovarian malignant tumor usually presenting in advance stage. Interval debulking surgery (IDS) post neoadjuvant chemotherapy (NACT) has been increasingly in use for the management of these patients. Chemotherapy response score (CRS) has been proposed for grading response of tubo-ovarian HGSC to NACT on the basis of examination of IDS specimens. Our aim was to evaluate CRS in post NACT cases, assess the interobserver agreement and correlate it to overall and progression- free survival...
September 15, 2017: Histopathology
https://www.readbyqxmd.com/read/28901666/clinicopathological-and-molecular-characteristics-of-pediatric-meningiomas
#3
Sudha Battu, Anupam Kumar, Pankaj Pathak, Suvendu Purkait, Linchi Dhawan, Mehar C Sharma, Ashish Suri, Manmohan Singh, Chitra Sarkar, Vaishali Suri
Molecular and clinical characteristics of pediatric meningiomas are poorly defined. Therefore, we analyzed clinical, morphological and molecular profiles of pediatric meningiomas. Forty pediatric meningiomas from January 2002 to June 2015 were studied. 1p36, 14q32 and 22q-deletion were assessed by fluorescent in situ hybridization and mutations of most relevant exons of AKT, SMO, KLF4, TRAF and pTERT using sequencing. Expression of GAB1, stathmin, progesterone receptor (PR), p53 along with MIB-1 LI was examined using immunohistochemistry...
September 13, 2017: Neuropathology: Official Journal of the Japanese Society of Neuropathology
https://www.readbyqxmd.com/read/28899434/effective-delivery-of-social-and-behavior-change-communication-through-a-care-group-model-in-a-supplementary-feeding-program
#4
Lauren Wilner, Devika J Suri, Breanne K Langlois, Shelley Marcus Walton, Beatrice Lorge Rogers
BACKGROUND: In 2014, an intervention aimed at increasing the oil in corn soy blend (CSB) porridge prepared by caregivers of children with moderate acute malnutrition was implemented in Southern Malawi. This analysis describes the flow of key messages delivered through the Care Group model during this intervention. METHODS: The intervention provided a supplementary food ration of CSB and oil and used a Care Group model in which healthcare workers were trained to deliver social and behavior change communication (SBCC) to care group volunteers who then delivered messages to caregivers of beneficiary children...
September 12, 2017: Journal of Health, Population, and Nutrition
https://www.readbyqxmd.com/read/28893396/early-results-of-robotically-assisted-mitral-valve-surgery-analysis-of-the-first-1000-cases
#5
A Marc Gillinov, Tomislav Mihaljevic, Hoda Javadikasgari, Rakesh M Suri, Stephanie L Mick, José L Navia, Milind Y Desai, Johannes Bonatti, Mitra Khosravi, Jay J Idrees, Ashley M Lowry, Eugene H Blackstone, Lars G Svensson
OBJECTIVE: The study objective was to assess the technical and process improvement and clinical outcomes of robotic mitral valve surgery by examining the first 1000 cases performed in a tertiary care center. METHODS: We reviewed the first 1000 patients (mean age, 56 ± 10 years) undergoing robotic primary mitral valve surgery, including concomitant procedures (n = 185), from January 2006 to November 2013. Mitral valve disease cause was degenerative (n = 960, 96%), endocarditis (n = 26, 2...
August 1, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28890314/bilateral-clavicular-attachment-of-omohyoid-muscle
#6
N Singh, M Kathole, J Kaur, V Mehta, R K Suri, G Rath, M Kohli
Omohyoid muscle present in cervical region is of particular importance to anatomists as it defines anteriorly the carotid triangle and divides the posterior cervical triangle. It has superior and inferior bellies and an intermediate common tendon. Like sternohyoid, sternothyroid and thyrohyoid muscles, omohyoid is also an infrahyoid muscle, but it differs from them in its course. The infrahyoid muscles are formed from a muscle primordium occurring in the anterior cervical area. Anderson (Anderson, 1881) theorized that the superior belly of the omohyoid muscle is a true infrahyoid muscle, whereas the inferior belly most likely shares a common embryology with the subclavius muscle...
September 7, 2017: Morphologie: Bulletin de L'Association des Anatomistes
https://www.readbyqxmd.com/read/28881798/role-of-a-kinase-anchor-protein-akap4-in-growth-and-survival-of-ovarian-cancer-cells
#7
Vikash Kumar, Nirmala Jagadish, Anil Suri
Ovarian cancer represents one of the most common malignancies among women with very high mortality rate worldwide. A-kinase anchor protein 4 (AKAP4), a unique cancer testis (CT) antigen has been shown to be associated with various malignant properties of cancer cells. However, its involvement in various molecular pathways in ovarian cancer remains unknown. In present investigation, employing gene silencing approach, we examined the role of AKAP4 in cell cycle, apoptosis and epithelial-mesenchymal transition (EMT)...
August 8, 2017: Oncotarget
https://www.readbyqxmd.com/read/28879901/braf-gene-alterations-and-enhanced-mammalian-target-of-rapamycin-signaling-in-gangliogliomas
#8
Aanchal Kakkar, Atreye Majumdar, Pankaj Pathak, Anupam Kumar, Kalpana Kumari, Manjari Tripathi, Mehar C Sharma, Vaishali Suri, Vivek Tandon, Sarat P Chandra, Chitra Sarkar
BACKGROUND: Gangliogliomas (GGs) are slow-growing glioneuronal tumors seen in children and young adults. They are associated with intractable epilepsy, and have recently been found to harbor BRAF (B- rapidly accelerated fibrosarcoma) gene mutations. However, the mammalian target of rapamycin (mTOR) signaling pathway, downstream of BRAF, has not been evaluated extensively in GGs. MATERIALS AND METHODS: GG cases were retrieved, clinical data obtained, and histopathological features reviewed...
September 2017: Neurology India
https://www.readbyqxmd.com/read/28879898/progressive-multifocal-leukoencephalopathy-in-a-44-year-old-male-with-idiopathic-cd4-t-lymphocytopenia-treated-with-mirtazapine-and-mefloquine
#9
Aruna Nambirajan, Vaishali Suri, Vijay Kataria, Mehar C Sharma, Vinay Goyal
Progressive multifocal leukoencephalopathy (PML) is an opportunistic viral infection of the central nervous system caused by the reactivation of John Cunningham virus (JCV) in immunocompromised patients, most commonly in human immunodeficiency virus (HIV) infection, and less commonly in those receiving various immunosuppressive regimens. Prognosis of untreated PML is grave and the mainstay of treatment is the reversal of immunosuppression, usually by institution of antiretroviral drugs in HIV patients and cessation of immunosuppressive therapies in others...
September 2017: Neurology India
https://www.readbyqxmd.com/read/28875824/applications-of-bauxite-residue-a-mini-review
#10
Ajay S Verma, Narendra M Suri, Suman Kant
Bauxite residue is the waste generated during alumina production by Bayer's process. The amount of bauxite residue (40-50 wt%) generated depends on the quality of bauxite ore used for the processing. High alkalinity and high caustic content in bauxite residue causes environmental risk for fertile soil and ground water contamination. The caustic (NaOH) content in bauxite residue leads to human health risks, like dermal problems and irritation to eyes. Moreover, disposal of bauxite residue requires a large area; such problems can only be minimised by utilising bauxite residue effectively...
September 1, 2017: Waste Management & Research
https://www.readbyqxmd.com/read/28862078/emotion-regulation-choice-the-role-of-environmental-affordances
#11
Gaurav Suri, Gal Sheppes, Gerald Young, Damon Abraham, Kateri McRae, James J Gross
Which emotion regulation strategy one uses in a given context can have profound affective, cognitive, and social consequences. It is therefore important to understand the determinants of emotion regulation choice. Many prior studies have examined person-specific, internal determinants of emotion regulation choice. Recently, it has become clear that external variables that are properties of the stimulus can also influence emotion regulation choice. In the present research, we consider whether reappraisal affordances, defined as the opportunities for re-interpretation of a stimulus that are inherent in that stimulus, can shape individuals' emotion regulation choices...
September 1, 2017: Cognition & Emotion
https://www.readbyqxmd.com/read/28859832/a-novel-and-robust-bayesian-approach-for-segmentation-of-psoriasis-lesions-and-its-risk-stratification
#12
Vimal K Shrivastava, Narendra D Londhe, Rajendra S Sonawane, Jasjit S Suri
BACKGROUND AND OBJECTIVE: The need for characterization of psoriasis lesion severity is clinically valuable and vital for dermatologists since it provides a reliable and precise decision on risk assessment. The automated delineation of lesion is a prerequisite prior to characterization, which is challenging itself. Thus, this paper has two major objectives: (a) design of a segmentation system which can model by learning the lesion characteristics and this is posed as a Bayesian model; (b) develop a psoriasis risk assessment system (pRAS) by crisscrossing the blocks which drives the fundamental machine learning paradigm...
October 2017: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/28854763/early-clinical-outcomes-of-a-new-posteriorly-stabilized-total-knee-arthroplasty-prosthesis-comparisons-with-two-established-prostheses
#13
Nimesh P Jain, Sung Yup Lee, Vivek M Morey, Suri Chong, Yeon Gwi Kang, Tae Kyun Kim
Purpose: We sought to determine whether early clinical performance of new posterior stabilized (PS) knee system, the Vega-PS (Aesculap), is better than that of two established total knee arthroplasty (TKA) prostheses, the E.motion-PS (Aesculap) and the Genesis II (Smith & Nephew) in terms of functional outcomes, patient satisfaction, and incidence of adverse events. Materials and Methods: We compared the clinical outcomes of 206 consecutive TKAs using Vega-PS with those of 205 TKAs using E...
September 1, 2017: Knee Surgery & related Research
https://www.readbyqxmd.com/read/28836045/extreme-learning-machine-framework-for-risk-stratification-of-fatty-liver-disease-using-ultrasound-tissue-characterization
#14
Venkatanareshbabu Kuppili, Mainak Biswas, Aswini Sreekumar, Harman S Suri, Luca Saba, Damodar Reddy Edla, Rui Tato Marinhoe, J Miguel Sanches, Jasjit S Suri
Fatty Liver Disease (FLD) is caused by the deposition of fat in liver cells and leads to deadly diseases such as liver cancer. Several FLD detection and characterization systems using machine learning (ML) based on Support Vector Machines (SVM) have been applied. These ML systems utilize large number of ultrasonic grayscale features, pooling strategy for selecting the best features and several combinations of training/testing. As result, they are computationally intensive, slow and do not guarantee high performance due to mismatch between grayscale features and classifier type...
August 23, 2017: Journal of Medical Systems
https://www.readbyqxmd.com/read/28831946/long-term-recovery-from-hurricane-sandy-evidence-from-a-survey-in-new-york-city
#15
Elisaveta P Petkova, Jaishree Beedasy, Eun Jeong Oh, Jonathan J Sury, Erin M Sehnert, Wei-Yann Tsai, Michael J Reilly
OBJECTIVES: This study aimed to examine a range of factors influencing the long-term recovery of New York City residents affected by Hurricane Sandy. METHODS: In a series of logistic regressions, we analyzed data from a survey of New York City residents to assess self-reported recovery status from Hurricane Sandy. RESULTS: General health, displacement from home, and household income had substantial influences on recovery. Individuals with excellent or fair health were more likely to have recovered than were individuals with poor health...
August 23, 2017: Disaster Medicine and Public Health Preparedness
https://www.readbyqxmd.com/read/28816210/dietary-deficiency-of-vitamin-a-among-rural-children-a-community-based-survey-using-a-food-frequency-questionnaire
#16
Shivali Suri, Dinesh Kumar, Ranjan Das
BACKGROUND: Overt vitamin A deficiency has been controlled in most parts of India, but prevalence of subclinical deficiency may still be high, which may enhance susceptibility to infections, reduce growth potential and also lead to higher mortality. We aimed to: (i) assess the consumption pattern of vitamin A-rich foods in children 1-5 years of age in rural Jammu; and (ii) estimate the dietary deficiency of vitamin A leading to risk of subclinical vitamin A deficiency in cluster- villages of the study area...
March 2017: National Medical Journal of India
https://www.readbyqxmd.com/read/28808792/using-natural-language-processing-of-free-text-radiology-reports-to-identify-type-1-modic-endplate-changes
#17
Hannu T Huhdanpaa, W Katherine Tan, Sean D Rundell, Pradeep Suri, Falgun H Chokshi, Bryan A Comstock, Patrick J Heagerty, Kathryn T James, Andrew L Avins, Srdjan S Nedeljkovic, David R Nerenz, David F Kallmes, Patrick H Luetmer, Karen J Sherman, Nancy L Organ, Brent Griffith, Curtis P Langlotz, David Carrell, Saeed Hassanpour, Jeffrey G Jarvik
Electronic medical record (EMR) systems provide easy access to radiology reports and offer great potential to support quality improvement efforts and clinical research. Harnessing the full potential of the EMR requires scalable approaches such as natural language processing (NLP) to convert text into variables used for evaluation or analysis. Our goal was to determine the feasibility of using NLP to identify patients with Type 1 Modic endplate changes using clinical reports of magnetic resonance (MR) imaging examinations of the spine...
August 14, 2017: Journal of Digital Imaging: the Official Journal of the Society for Computer Applications in Radiology
https://www.readbyqxmd.com/read/28793834/a-preliminary-examination-of-the-role-of-psychotherapist-fidelity-on-outcomes-of-cognitive-processing-therapy-during-an-rct-for-military-sexual-trauma-related-ptsd
#18
Nicholas Holder, Ryan Holliday, Rush Williams, Kacy Mullen, Alina Surís
While cognitive processing therapy (CPT) is an effective evidence-based treatment for many veterans with military-related post-traumatic stress disorder (PTSD), not all veterans experience therapeutic benefit. To account for the discrepancy in outcomes, researchers have investigated patient- and research design-related factors; however, therapist factors (e.g. fidelity) have received less attention. The present study is a preliminary examination of the effect of psychotherapists' fidelity during CPT on clinical outcomes during a randomized clinical trial (RCT) for military sexual trauma-related PTSD...
August 10, 2017: Cognitive Behaviour Therapy
https://www.readbyqxmd.com/read/28781823/inappropriate-shock-in-a-subcutaneous-cardiac-defibrillator-due-to-residual-air
#19
Shawn Lee, Nektarios Souvaliotis, Davendra Mehta, Ranjit Suri
Inappropriate shock due to residual air in subcutaneous implantable cardiac defibrillators is not a well-known complication. Obtaining overpenetrated X-rays, recognizing electrocardiogram findings, limiting blunt finger dissection, and switching to sense at another vector are techniques which might lead to avoidance of unnecessary wound exploration or device removal.
August 2017: Clinical Case Reports
https://www.readbyqxmd.com/read/28777935/de-novo-mutations-in-ywhag-cause-early-onset-epilepsy
#20
Ilaria Guella, Marna B McKenzie, Daniel M Evans, Sarah E Buerki, Eric B Toyota, Margot I Van Allen, Mohnish Suri, Frances Elmslie, Marleen E H Simon, Koen L I van Gassen, Delphine Héron, Boris Keren, Caroline Nava, Mary B Connolly, Michelle Demos, Matthew J Farrer
Massively parallel sequencing has revealed many de novo mutations in the etiology of developmental and epileptic encephalopathies (EEs), highlighting their genetic heterogeneity. Additional candidate genes have been prioritized in silico by their co-expression in the brain. Here, we evaluate rare coding variability in 20 candidates nominated with the use of a reference gene set of 51 established EE-associated genes. Variants within the 20 candidate genes were extracted from exome-sequencing data of 42 subjects with EE and no previous genetic diagnosis...
August 3, 2017: American Journal of Human Genetics
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