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https://www.readbyqxmd.com/read/28098082/occupational-health-profile-of-workers-employed-in-the-manufacturing-sector-of-india
#1
REVIEW
Shivali Suri, Ranjan Das
BACKGROUND: The occupational health scenario of workers engaged in the manufacturing sector in India deserves attention for their safety and increasing productivity. We reviewed the status of the manufacturing sector, identified hazards faced by workers, and assessed the existing legislations and healthcare delivery mechanisms. METHODS: From October 2014 to March 2015, we did a literature review by manual search of pre-identified journals, general electronic search, electronic search of dedicated websites/databases and personal communication with experts of occupational health...
September 2016: National Medical Journal of India
https://www.readbyqxmd.com/read/28097811/fc-silent-anti-cd154-domain-antibody-effectively-prevents-non-human-primate-renal-allograft-rejection
#2
Steven C Kim, Walter Wakwe, Laura B Higginbotham, David V Mathews, Cynthia P Breeden, Allison C Stephenson, Joe Jenkins, Elizabeth Strobert, Karen Price, Laura Price, Robert Kuhn, Haiqing Wang, Aaron Yamniuk, Suzanne Suchard, Alton B Farris, Thomas C Pearson, Christian P Larsen, Mandy L Ford, Anish Suri, Steven Nadler, Andrew B Adams
The advent of costimulation blockade provides the prospect for targeted therapy with improved graft survival in transplant patients. Perhaps the most effective costimulation blockade in experimental models is the use of reagents to block the CD40/CD154 pathway. Unfortunately, successful clinical translation of anti-CD154 therapy has not been achieved. In an attempt to develop an agent that is as effective as previous CD154 blocking antibodies but lacks the risk of thromboembolism, we evaluated the efficacy and safety of a novel anti-human CD154 domain antibody (dAb, BMS-986004)...
January 17, 2017: American Journal of Transplantation
https://www.readbyqxmd.com/read/28096640/prevalence-of-metabolic-syndrome-in-pre-and-post-menopausal-women-a-prospective-study-from-apex-institute-of-north-india
#3
Sandeep Sharma, Neelam Aggarwal, Bharti Joshi, Vanita Suri, Sanjay Badada
BACKGROUND: The metabolic syndrome (MS) (syndrome X, insulin resistance syndrome) is a constellation of metabolic abnormalities and a complex predisease state that predicts future development of type 2 diabetes mellitus and cardiovascular disease. Menopausal transition and postmenopausal state are considered as a vulnerable period for developing MS, and this increased risk has been attributed to decreasing estrogen levels with an increasing risk of insulin resistance following menopause...
October 2016: Journal of Mid-life Health
https://www.readbyqxmd.com/read/28094031/patients-receiving-frequent-hemodialysis-have-better-health-related-quality-of-life-compared-to-patients-receiving-conventional-hemodialysis
#4
Amit X Garg, Rita S Suri, Paul Eggers, Fredric O Finkelstein, Tom Greene, Paul L Kimmel, Alan S Kliger, Brett Larive, Robert M Lindsay, Andreas Pierratos, Mark Unruh, Glenn M Chertow
Most patients with end-stage kidney disease value their health-related quality of life (HRQoL) and want to know how it will be affected by their dialysis modality. We extended the findings of two prior clinical trial reports to estimate the effects of frequent compared to conventional hemodialysis on additional measures of HRQoL. The Daily Trial randomly assigned 245 patients to receive frequent (six times per week) or conventional (three times per week) in-center hemodialysis. The Nocturnal Trial randomly assigned 87 patients to receive frequent nocturnal (six times per week) or conventional (three times per week) home hemodialysis...
January 13, 2017: Kidney International
https://www.readbyqxmd.com/read/28089254/volumetric-analysis-of-carotid-plaque-components-and-cerebral-microbleeds-a-correlative-study
#5
Luca Saba, Roberto Sanfilippo, Michele di Martino, Michele Porcu, Roberto Montisci, Pierleone Lucatelli, Michele Anzidei, Marco Francone, Jasjit S Suri
PURPOSE: The purpose of this work was to explore the association between carotid plaque volume (total and the subcomponents) and cerebral microbleeds (CMBs). MATERIALS AND METHODS: Seventy-two consecutive (male 53; median age 64) patients were retrospectively analyzed. Carotid arteries were studied by using a 16-detector-row computed tomography scanner whereas brain was explored with a 1.5 Tesla system. CMBs were studied using a T2*-weighted gradient-recalled echo sequence...
January 11, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28067128/study-of-kite-string-injuries-in-western-india
#6
Chetan Prajapati, Abhay Agrawal, Ravish Atha, Manav P Suri, Jayesh P Sachde, M F Shaikh
A prospective analysis of 104 patients (outdoor and indoor) with manja (powdered glass coated kite string) injury from January 2011 to January 2015 was carried out at Civil Hospital Ahmedabad. All patients were analysed for mode and severity of injury, site of injury, associated injuries, activity being performed when injury occurred, the clinical diagnosis and treatment required. Analysis of collected data revealed that majority of the injuries occurred while driving or in pedestrians with the neck being the most commonly affected body part...
March 2017: International Journal of Injury Control and Safety Promotion
https://www.readbyqxmd.com/read/28050451/choriocarcinoma-in-ongoing-pregnancy-presenting-with-intracranial-metastasis
#7
Sujata Siwatch, Vanita Suri, Pooja Sikka, Neelam Aggarwal, Seema Chopra
Choriocarcinoma presents usually as persistent trophoblastic disease, with prognosis worsening with duration from antecedent pregnancy. We present a unique case of a woman with choriocarcinoma who presented in the third trimester of pregnancy with eclampsia. She was managed with magnesium sulphate and underwent a caesarean section. However, she developed seizures in the post-partum period that were further investigated and attributed to intracranial metastatic lesions of Gestational Trophoblastic Neoplasia (GTN)...
November 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28039145/blue-nails-in-a-child-with-hiv-infection
#8
Ankur Kumar Jindal, Deepti Suri
No abstract text is available yet for this article.
December 30, 2016: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28035316/primary-pediatric-mid-brain-lymphoma-report-of-a-rare-pediatric-tumor-in-a-rare-location
#9
Rony Benson, Supriya Mallick, Suvendu Purkait, Vaishali Suri, K P Haresh, Subhash Gupta, Dayanand Sharma, Pramod Kumar Julka, Goura Kishore Rath
Primary central nervous system lymphoma (PCNSL) is a rare disease in pediatric age group. A thirteen-year-old male child presented with complaints of headache for six months, vomiting and diplopia for three days. Magnetic resonance imaging of the brain showed a single lesion of 1.7 cm × 1.6 cm × 1.6 cm in the mid brain and tectum. He underwent a gross total resection of the tumor. The histopathological evaluation revealed B cell high grade non Hodgkin lymphoma. The patient was treated with High dose methotrexate and cranio spinal radiation...
December 16, 2016: World Journal of Clinical Cases
https://www.readbyqxmd.com/read/28007240/the-society-of-thoracic-surgeons-2017-clinical-practice-guidelines-for-the-surgical-treatment-of-atrial-fibrillation
#10
Vinay Badhwar, J Scott Rankin, Ralph J Damiano, A Marc Gillinov, Faisal G Bakaeen, James R Edgerton, Jonathan M Philpott, Patrick M McCarthy, Steven F Bolling, Harold G Roberts, Vinod H Thourani, Rakesh M Suri, Richard J Shemin, Scott Firestone, Niv Ad
Surgical ablation for atrial fibrillation (AF) can be performed without additional risk of operative mortality or major morbidity, and is recommended at the time of concomitant mitral operations to restore sinus rhythm. (Class I, Level A) Surgical ablation for AF can be performed without additional operative risk of mortality or major morbidity, and is recommended at the time of concomitant isolated aortic valve replacement, isolated coronary artery bypass graft surgery, and aortic valve replacement plus coronary artery bypass graft operations to restore sinus rhythm...
January 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28003892/early-versus-late-tracheostomy-for-patients-with-high-and-low-cervical-spinal-cord-injuries
#11
Akram H Guirgis, Venugopal K Menon, Neelam Suri, Nilay Chatterjee, Emil Attallah, Maged Y Saad, Shereen Elshaer
OBJECTIVES: This study aimed to evaluate the effects of early versus late tracheostomies among patients with cervical spinal cord injuries (CSCIs). METHODS: This retrospective study included 69 adult CSCI patients who underwent bedside percutaneous tracheostomies at the Intensive Care Unit of Khoula Hospital, Muscat, Oman, between January 2011 and October 2015. The tracheostomy was considered early if the procedure took place within one week of the CSCI. The impact of an early tracheostomy on patient outcomes was analysed in terms of duration of mechanical ventilation and intensive care unit (ICU) stay among patients with high (C1-C2 vertebrae) and low (C3-C7 vertebrae) CSCIs...
November 2016: Sultan Qaboos University Medical Journal
https://www.readbyqxmd.com/read/27999985/mri-of-endolymphatic-hydrops-in-patients-with-meniere-s-disease-a-case-controlled-study-with-a-simplified-classification-based-on-saccular-morphology
#12
Arnaud Attyé, Michael Eliezer, Naïla Boudiaf, Irène Tropres, David Chechin, Sébastien Schmerber, Georges Dumas, Alexandre Krainik
OBJECTIVES: Endolymphatic hydrops (EH) can be studied in patients by MRI. With the semi-quantitative grading system, previous imaging studies showed discrepancies in the occurrence and grading of EH in patients with Meniere's disease (MD). Here, we compared the inversion of the saccule to utricle area ratio (SURI) with the semi-quantitative method of grading conventionally used to diagnose MD. METHODS: Imaging was carried out on a 3-T MRI scanner. We performed 3D-FLAIR sequences 4 h after a single intravenous dose of contrast agent...
December 20, 2016: European Radiology
https://www.readbyqxmd.com/read/27999505/osteochondral-allograft-transplantation-for-femoral-trochlear-dysplasia
#13
Dharmpal V Vansadia, James R Heltsley, Scott Montgomery, Misty Suri, Deryk G Jones
BACKGROUND: The risk factors for patellofemoral joint instability include laxity of medial patellar restraints, abnormal limb geometry, femoral and tibial malrotation, patella alta, and trochlear dysplasia. Femoral trochlear dysplasia is characterized by a hypoplastic or shallow trochlear groove. CASE REPORT: We report the case of a 31-year-old female with trochlear dysplasia and recurrent patella dislocations, laxity of the medial patellofemoral ligament (MPFL), and high-grade chondromalacia of the trochlea and the patella...
2016: Ochsner Journal
https://www.readbyqxmd.com/read/27999503/factors-affecting-the-union-of-opening-wedge-high-tibial-osteotomy-using-a-titanium-wedge-plate
#14
Husam T Nawas, Dharmpal V Vansadia, James R Heltsley, Misty Suri, Scott Montgomery, Deryk G Jones
BACKGROUND: Factors that can affect the success rate of high tibial osteotomy (HTO) include patient selection, surgical technique, type of fixation hardware, supplemental fixation, choice of bone graft, and rehabilitation protocol. The purpose of this study was to define the role of cortical hinge fractures in the risk of nonunion and collapse of opening wedge high tibial osteotomy. METHODS: A total of 60 patients (mean age, 40 years) who underwent 64 primary HTO procedures were identified from our operational database and observed at a mean follow-up of 2 years...
2016: Ochsner Journal
https://www.readbyqxmd.com/read/27994348/a-call-for-neurologists-to-take-up-stroke-intervention
#15
REVIEW
Vasantha M Padma, Rohit Bhatia, Gigy Kuruttukulam, Anand Alurkar, Kewal Krishan Talwar, Dheeraj Khurana, Subhash Kaul, Vinit Suri, Gagandeep Singh, Vikram Huded
Recent data have provided overwhelming evidence in favor of benefits of emergent endovascular intervention in large vessel acute ischemic stroke (AIS). India with its large population has a huge burden of AIS. Hence, neurologists need to gear up to the new challenge of providing interventional care to huge populations of AIS in the country. The best way to cover this unprecedented unmet need is to encourage neurologists to take up interventional subspecialty interests through new but sound training pathways...
October 2016: Annals of Indian Academy of Neurology
https://www.readbyqxmd.com/read/27993893/genome-wide-chip-seq-analysis-of-ezh2-mediated-h3k27me3-target-gene-profile-highlights-differences-between-low-and-high-grade-astrocytic-tumors
#16
Vikas Sharma, Prit Benny Malgulwar, Suvendu Purkait, Vikas Patil, Pankaj Pathak, Rahul Agarwal, Ritu Kulshreshtha, Supriya Mallick, Pramod Kumar Julka, Ashish Suri, Bhawani Shankar Sharma, Vaishali Suri, Mehar Chand Sharma, Chitra Sarkar
Enhancer of Zeste Homologue-2(EZH2) is a key epigenetic regulator that functions as oncogene and also known for inducing altered H3K27me3 mark in various tumors. However, H3K27me3 targets and their precise relationship with gene expression are largely unknown in astrocytic tumors. In this study, we checked EZH2 mRNA and protein expression in 90 astrocytic tumors of different grades using qPCR and IHC,respectively. Further, genome wide ChIP-seq analysis for H3K27me3 modification was also performed on 11 Glioblastomas(GBMs) and 2 Diffuse astrocytoma(DAs) samples...
December 17, 2016: Carcinogenesis
https://www.readbyqxmd.com/read/27992858/proteins-that-accumulate-with-age-in-human-skeletal-muscle-aggregates-contribute-to-declines-in-muscle-mass-and-function-in-caenorhabditis-elegans
#17
Srinivas Ayyadevara, Meenakshisundaram Balasubramaniam, Pooja Suri, Samuel G Mackintosh, Alan J Tackett, Dennis H Sullivan, Robert J Shmookler Reis, Richard A Dennis
Protein aggregation increases with age in normal tissues, and with pathology and age in Alzheimer's hippocampus and mouse cardiac muscle. We now ask whether human skeletal muscle accumulates aggregates with age. Detergent-insoluble protein aggregates were isolated from vastus lateralis biopsies from 5 young (23-27 years of age) and 5 older (64-80 years) adults. Aggregates, quantified after gel electrophoresis, contain 2.1-fold more protein (P<0.0001) when isolated from older subjects relative to young. Of 515 proteins identified by liquid chromatography coupled to tandem mass spectrometry, 56 (11%) were significantly more abundant in older muscle, while 21 (4%) were depleted with age (each P<0...
December 15, 2016: Aging
https://www.readbyqxmd.com/read/27981421/identification-of-binding-mode-and-prospective-structural-features-of-novel-nef-protein-inhibitors-as-potential-anti-hiv-drugs
#18
Suri Moonsamy, Soumendranath Bhakat, Muthusamy Ramesh, Mahmoud E S Soliman
Human immunodeficiency virus (HIV)-negative factor (Nef) protein is an accessory pathogenic factor, which plays a significant role in acquired immune deficiency syndrome (AIDS). Nef deficient HIV virus took a longer time to progress into AIDS. Therefore, targeting Nef protein is considered as a key strategy towards HIV/AIDS treatment. Up-to-date, only few compounds were reported as Nef inhibitors. This has prompted us to provide a first account of an integrated computational framework in order to identify more potential Nef inhibitors...
December 16, 2016: Cell Biochemistry and Biophysics
https://www.readbyqxmd.com/read/27981353/adolescents-with-a-smartphone-sleep-less-than-their-peers
#19
Angélick Schweizer, André Berchtold, Yara Barrense-Dias, Christina Akre, Joan-Carles Suris
: Many studies have shown that the use of electronic media is related to sleep disturbance, but few have examined the impact of smartphones. The objective of this study was to assess longitudinally whether acquiring a smartphone had an effect on adolescents' sleeping duration. The study included 591 adolescents observed at baseline (T0, Spring 2012; mean age 14.3 years, 288 females) and 2 years later (T1). They were divided into owners (those owning a smartphone at T0 and T1; N = 383), new owners (those owning a smartphone at T1 but not at T0; N = 153), and non-owners (those not owning a smartphone at any time-point; N = 55)...
January 2017: European Journal of Pediatrics
https://www.readbyqxmd.com/read/27970424/achieving-optimal-fit-to-survival-data-using-cubic-spline-models-a-case-study-comparing-the-fit-of-standard-and-cubic-spline-models-to-survival-data-from-the-icon6-study
#20
R Hettle, A Sackeyfio, G Suri
No abstract text is available yet for this article.
November 2016: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
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