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Shana M Winkel, Melanie D Trenhaile-Grannemann, Dana M Van Sambeek, Phillip S Miller, Jaime Salcedo, Daniela Barile, Thomas E Burkey
An ongoing study at the University of Nebraska-Lincoln (which included 14 batches of gilts; n = 90 gilts/batch) demonstrated that energy restriction during the developmental period of a gilt increases longevity and may also have beneficial effects on progeny health and growth; particularly, parity 1 progeny. Therefore, we hypothesized that energy restriction during gilt development may impact milk nutrient profile, milk oligosaccharides, and post-natal progeny biomarkers. During the development period, batch 14 gilts (n = 128, 8 gilts/pen) were fed three dietary treatments including: 1) Control diet formulated to NRC (2012) specifications (CTL); 2) Restricted (20% energy restriction via addition of 40% soy hulls; RESTR); and, 3) CTL diet plus addition of crystalline amino acids equivalent to the SID Lys:ME of the RESTR diet (CTL+)...
May 31, 2018: Journal of Animal Science
Annette C Moser, Sidney Trenhaile, Kati Frankenberg
Antibody-antigen interactions are vital in immunoassay development and can determine detection limits and analysis times. Capillary electrophoresis (CE) is a powerful technique that can be used to quantify antibody-antigen interactions. These CE methods range from simple separations of a premixed antibody and antigen sample applied as a short plug to allow for separation of complex, free antibody, and free antigen to more complex systems which inject complexed samples in the presence of antibody or antigen; or even injections of antibody and antigen sequentially...
March 15, 2018: Methods: a Companion to Methods in Enzymology
Theodore L Schoenfeldt, Scott Trenhaile, Richard Olson
Patients with shoulder pain are commonly seen in adult primary care, and are typically referred to musculoskeletal specialists when their symptoms are persistent. Rotator cuff disorders (RCD) most commonly underlie non-traumatic shoulder pain in adults, and glenohumeral osteoarthritis (GHOA) has been considered to be relatively uncommon (Nakagawa et al., J Shoulder Elb Surg 8:580-584, 1999). Our impression has been that GHOA affects significant numbers of patients, is less well studied, and may be under recognized...
February 8, 2018: Rheumatology International
Allison J Rao, Nikhil N Verma, Scott W Trenhaile
Surgical repair of a Bankart lesion requires thorough recognition of the capsulolabral attachment and adequate visualization for suture anchor repair. The glenoid labrum usually detaches from its capsule and bony attachment anteriorly and inferiorly; however, the labral and capsule detachment can sometimes extend beyond this zone of injury. Identification and repair may require additional viewing and working portals to allow for ease of suture passage and anchor placement. This technique guide describes a case scenario of a Bankart lesion with anterior extension of the capsular tear, repaired with use of 2 anterior working portals...
October 2017: Arthroscopy Techniques
Allison J Rao, Eamon Bernardoni, Nikhil Verma, Scott Trenhaile
Biceps tenodesis remains a popular choice for treating anterior shoulder pain in the setting of primary biceps tendinitis or biceps pain due to concomitant glenohumeral joint pathology. A variety of surgical approaches and fixation construct options are available for biceps tenodesis. The advantages of an all-arthroscopic biceps tenodesis include anatomic maintenance of the length-tension relation with strength preservation and improved cosmetic results. This technique can be technically challenging but allows for a minimally invasive approach to anchor the biceps...
October 2017: Arthroscopy Techniques
Eric J Cotter, Rachel M Frank, Scott W Trenhaile
Traumatic glenohumeral dislocations often result in significant injury to the anterior-inferior labrum, most commonly leading to recurrent anterior instability. While in skeletally immature patients, shoulder trauma more commonly results in fracture versus a true dislocation, shoulder instability does occur and can be difficult to manage in the setting of open physes. In any event, the goal of treatment is to reduce the risk of recurrence and allow full participation in activities, including sports. Arthroscopic stabilization has been shown to be an effective treatment option for young patients, with good return to sport rates; however, the vast majority of literature on shoulder instability in the youth patient population focuses on anterior instability...
October 2017: Arthroscopy Techniques
H R Wijesena, C A Lents, J-J Riethoven, M D Trenhaile-Grannemann, J F Thorson, B N Keel, P S Miller, M L Spangler, S D Kachman, D C Ciobanu
Genetic variants associated with traits such as age at puberty and litter size could provide insight into the underlying genetic sources of variation impacting sow reproductive longevity and productivity. Genomewide characterization and gene expression profiling were used using gilts from the University of Nebraska-Lincoln swine resource population ( = 1,644) to identify genetic variants associated with age at puberty and litter size traits. From all reproductive traits studied, the largest fraction of phenotypic variation explained by the Porcine SNP60 BeadArray was for age at puberty (27...
September 2017: Journal of Animal Science
M D Trenhaile, J L Petersen, S D Kachman, R K Johnson, D C Ciobanu
High-density genotype data were analyzed in three lines of swine that express substantial variation in sow fertility to uncover regions of the genome potentially influenced during selection for litter size traits. The experimental lines examined include the Nebraska Index Line (NIL), which has been subjected to long-term selection for litter size; a control line derived from the same population that founded NIL; and a commercial Duroc × Hampshire (D × H) population, in which no selection for litter size was practiced...
October 2016: Animal Genetics
Peter Nissen Chalmers, Geoff S Van Thiel, Scott W Trenhaile
Surgical repair, reduction, fixation, and reconstruction for glenohumeral trauma, instability, and degenerative joint disease often require an open surgical exposure. Open shoulder surgery is challenging because the deltoid and rotator cuff musculature envelop the joint, and in most approaches, exposure is limited by the proximity and importance of the axillary nerve. An understanding of the importance of the deltoid and the rotator cuff for glenohumeral function has led to a progression of innovative, advanced, and less invasive approaches to the shoulder...
April 2016: Journal of the American Academy of Orthopaedic Surgeons
K L Lucot, M L Spangler, M D Trenhaile, S D Kachman, D C Ciobanu
Genomic information could be used efficiently to improve traits that are expensive to measure, sex limited or expressed late in life. This study analyzed the phenotypic variation explained by major SNPs and windows for age at puberty in gilts, an indicator of reproductive longevity. A genome-wide association study using 56, 424 SNPs explained 25.2% of the phenotypic variation in age at puberty in a training set (n = 820). All SNPs from the top 10% of 1-Mb windows explained 33.5% of the phenotypic variance compared to 47...
August 2015: Animal Genetics
Margaret E Gibson, Daniel Gurley, Scott Trenhaile
Isolated traumatic subscapularis tendon tears are uncommon at any age. In adolescent patients, this type of injury is even more infrequent and usually presents as a bony avulsion of the lesser tuberosity. This report reviews a case of an adolescent American football player sustaining a posterior impact to an abducted, extended arm that resulted in an isolated subscapularis tendon tear. Magnetic resonance imaging of the shoulder revealed an isolated subscapularis tear retracted 1.6 cm without bony avulsion from the lesser tuberosity...
May 2013: Sports Health
Peter N Chalmers, Rachel M Frank, Anil K Gupta, Adam B Yanke, Scott W Trenhaile, Anthony A Romeo, Bernard R Bach, Nikhil N Verma
Surgical management of massive rotator cuff tears remains challenging, with failure rates ranging from 20% to 90%. Multiple different arthroscopic and open techniques have been described, but there is no current gold standard. Failure after rotator cuff repair is typically multifactorial; however, failure of tendon-footprint healing is often implicated. Patch augmentation has been described as a possible technique to augment the biology of rotator cuff repair in situations of compromised tendon quality and has shown promising short-term results...
2013: Arthroscopy Techniques
Mark A Slabaugh, Rachel M Frank, Geoffrey S Van Thiel, Rebecca M Bell, Vincent M Wang, Scott Trenhaile, Matthew T Provencher, Anthony A Romeo, Nikhil N Verma
PURPOSE: To evaluate the effect of screw length and diameter on the mechanical properties of biceps tenodesis (BT) with an interference screw in 2 different locations (proximal and distal). METHODS: We randomized 42 fresh-frozen human cadaveric shoulders (mean age, 65 ± 8 years) into 6 groups (n = 7): arthroscopic proximal BT using 7 × 15-, 7 × 25-, 8 × 15-, or 8 × 25-mm interference screws or distal subpectoral BT with 7 × 15- or 8 × 15-mm interference screws...
February 2011: Arthroscopy: the Journal of Arthroscopic & related Surgery
Felix H Savoie, Scott W Trenhaile, John Roberts, Larry D Field, J Randall Ramsey
BACKGROUND: Little data exist regarding the treatment of young high school and college athletes with medial ulnar collateral ligament insufficiency of the elbow. It would be logical to assume that younger patients would have less damage to the ligament, allowing the possibility of repair. HYPOTHESIS: Many young athletes with injuries to the medial ulnar collateral ligament have proximal or distal injuries that may be amenable to repair, indicating that graft reconstruction may not always be necessary to obtain satisfactory results...
June 2008: American Journal of Sports Medicine
David Argo, Scott W Trenhaile, Felix H Savoie, Larry D Field
BACKGROUND: As women become more involved in athletic activity, injuries specific to this population also increase. No data exist regarding operative treatment of female patients with elbow instability secondary to ulnar collateral ligament insufficiency. HYPOTHESIS: Women with symptomatically unstable elbows who failed nonoperative treatment will improve after surgical intervention. STUDY DESIGN: Case series; Level of evidence, 4. METHODS: Nineteen women were retrospectively evaluated using the Andrews and Carson Elbow Outcome Score...
March 2006: American Journal of Sports Medicine
Robert S Neuwirth, Franklin D Loffer, Therese Trenhaile, Bruce Levin
STUDY OBJECTIVE: To assess the incidence of endometrial cancer in 509 women who had undergone hysteroscopic endometrial ablation in two centers between 1978 and 1994. All patients had normal endometrial histology before ablation. DESIGN: Retrospective cohort study (Canadian Task Force classification II-2). SETTING: Teaching hospital-affiliated private practices. PATIENTS: Five hundred nine women with perimenopausal bleeding...
November 2004: Journal of the American Association of Gynecologic Laparoscopists
Scott W Trenhaile, Felix H Savoie
No abstract text is available yet for this article.
February 2002: Arthroscopy: the Journal of Arthroscopic & related Surgery
T R Trenhaile, M A Killackey
OBJECTIVE: To describe five cases of primary pelvic non-Hodgkin's lymphoma, a rare gynecologic malignancy. METHODS: The charts of five women with primary pelvic non-Hodgkin's lymphoma were reviewed. Histologic classification was based on the Working Formulation, and staging was based on the Ann Arbor system. Disease status was monitored with physical examination and imaging studies. RESULTS: During a 10-month period, five women were diagnosed with primary pelvic non-Hodgkin's lymphoma, including one parasacral, one uterine, one vaginal, and two ovarian tumors...
May 2001: Obstetrics and Gynecology
J V Nepola, S W Trenhaile, M A Miranda, S L Butterfield, D C Fredericks, B L Riemer
BACKGROUND: Residual vertical displacement is often cited as being related to poor outcome in patients with pelvic injuries. This study attempts to clarify the relationship between residual vertical displacement and functional outcome. METHODS: From 1982 to 1989, over 500 patients with pelvic ring injuries were treated at two Level I trauma centers. Thirty-three patients with vertical shear (Tile C) fractures and residual displacement (2-52 mm) were evaluated. Outcomes were quantified by using SF-36 Short-Form Health Survey (SF-36) and the Iowa Pelvic Score (IPS)...
June 1999: Journal of Trauma
S Ryan, A Sandler, S Trenhaile, K Ephgrave, S Garner
BACKGROUND: Elevations in levels of the pancreatic enzymes amylase and lipase occur frequently after trauma. The purpose of this prospective study was to examine the incidence of these enzyme elevations in patients suffering blunt trauma, their natural history, and their relationship to posttraumatic pancreatitis. METHODS: One hundred consecutive trauma patients were studied on admission to the surgical intensive care unit with daily serum amylase and lipase measurements, which were blinded to the clinical service...
October 1994: Surgery
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