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https://www.readbyqxmd.com/read/28445573/the-management-of-antiplatelet-and-antithrombotic-regimens-in-patients-with-mechanical-valves-undergoing-percutaneous-coronary-intervention-a-forgotten-cohort
#1
Cian P McCarthy, Subodh Verma, Deepak L Bhatt
No abstract text is available yet for this article.
April 26, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/28444603/physiological-functioning-of-lagerstroemia-speciosa-l-under-heavy-roadside-traffic-an-approach-to-screen-potential-species-for-abatement-of-urban-air-pollution
#2
H Singh, Savita, R Sharma, S Sinha, M Kumar, P Kumar, A Verma, S K Sharma
The mitigation potential of avenue tree species needs a sound understanding, especially for landscape planning or planting tree species on roadside, especially in city limits where there is huge traffic due to more number of vehicles. A preliminary study was conducted to investigate the impact of heavy traffic movement and pollution thereof on physiological functioning of Lagerstroemia speciosa trees planted on roadside in terms of carbon absorption, mitigation potential and adaptive behavior. Trees on roadside exhibited reduced carbon assimilation (36...
May 2017: 3 Biotech
https://www.readbyqxmd.com/read/28444489/biodegradable-stents-for-caustic-esophageal-strictures-do-they-work
#3
Rakesh Kochhar, Jayanta Samanta, Jahangeer Basha, Abhai Verma, Gourdas Choudhuri, Sundeep Lakhtakia, D Nageshwar Reddy
Biodegradable (BD) stents have been used for the management of various esophageal strictures (ES) but the experience of its use in caustic strictures is limited. The present study, aimed at evaluating efficacy of BD stents for the treatment of refractory caustic-induced ES, was a retrospective multi-center study conducted at three tertiary care centers in India wherein adult patients with refractory caustic induced strictures underwent placement of a BD stent. Patients were followed up for immediate complications and long term outcome...
April 25, 2017: Dysphagia
https://www.readbyqxmd.com/read/28443934/hg-ii-and-pd-ii-complexes-with-a-new-selenoether-bridged-biscarbene-ligand-efficient-mono-and-bis-arylation-of-methyl-acrylate-with-a-pincer-biscarbene-pd-ii-precatalyst
#4
Rishu, Billa Prashanth, Deependra Bawari, Ushnish Mandal, Aditya Verma, Angshuman Roy Choudhury, Sanjay Singh
Two equivalents of 1-benzyl-3-bromoethylbenzimidazolium bromide couple with Na2Se to produce the first selenoether bridged bis-benzimidazolium salt (LH2)Br2. The nitrate (LH2)(NO3)2 and tetrafluoroborate (LH2)(BF4)2 salts were also synthesized from (LH2)Br2. The reaction of Hg(OAc)2 with (LH2)Br2 gave the first pseudo pincer carbene mercury complex, [Hg(L-κ(2)C)][HgBr4] (C1). Different complexes of Pd(ii) with selenoether bridged carbene were obtained using (LH2)Br2 and (LH2)(NO3)2. Syntheses of these complexes were dependent on the counter anion and the temperature...
April 26, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28442800/what-puts-them-at-risk-a-cross-sectional-case-control-survey-of-demographic-profile-and-sexual-behavior-of-patients-with-sexually-transmitted-infections-at-a-tertiary-care-center-in-north-india
#5
Rama Raj, Vishal Gupta, Mona Pathak, Vishnubhatla Sreenivas, Seema Sood, Sarman Singh, Kaushal K Verma, Neena Khanna, Bimal K Das, Somesh Gupta
BACKGROUND: Sexually transmitted infections (STIs) are a major public health problem in developing nations. Identification of risk factors can help in formulating effective strategies against them. The present study was conducted in a tertiary care hospital in North India over 1 year to identify the risk factors associated with STIs. MATERIALS AND METHODS: A questionnaire-based cross-sectional case-control survey was conducted where participants answered questions on demographic details, sexual behavior, and awareness of STIs...
January 2017: Indian Journal of Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/28439448/spatial-determinants-of-ebola-virus-disease-risk-for-the-west-african-epidemic
#6
Kate Zinszer, Kathryn Morrison, Aman Verma, John S Brownstein
INTRODUCTION: Although many studies have investigated the probability of Ebola virus disease (EVD) outbreaks while other studies have simulated the size and speed of EVD outbreaks, few have investigated the environmental and population-level predictors of Ebola transmission once an outbreak is underway. Identifying strong predictors of transmission could help guide and target limited public health resources during an EVD outbreak. We examined several environmental and population-level demographic predictors of EVD risk from the West African epidemic...
March 31, 2017: PLoS Currents
https://www.readbyqxmd.com/read/28438143/erratum-to-high-pre-diagnosis-attrition-among-patients-with-presumptive-mdr-tb-an-operational-research-from-bhopal-district-india
#7
Hemant Deepak Shewade, Arun M Kokane, Akash Ranjan Singh, Manoj Verma, Malik Parmar, Ashish Chauhan, Sanjay Singh Chahar, Manoj Tiwari, Sheeba Naz Khan, Vivek Gupta, Jaya Prasad Tripathy, Mukesh Nagar, Sanjai Kumar Singh, Pradeep Kumar Mehra, Ajay M V Kumar
No abstract text is available yet for this article.
April 24, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28437948/uv-sensitive-superconducting-nanowire-single-photon-detectors-for-integration-in-an-ion-trap
#8
D H Slichter, V B Verma, D Leibfried, R P Mirin, S W Nam, D J Wineland
We demonstrate superconducting nanowire single photon detectors with 76 ± 4% system detection efficiency at a wavelength of 315 nm and an operating temperature of 3.2 K, with a background count rate below 1 count per second at saturated detection efficiency. We propose integrating these detectors into planar surface electrode radio-frequency Paul traps for use in trapped ion quantum information processing. We operate detectors integrated into test ion trap structures at 3.8 K both with and without typical radio-frequency trapping electric fields...
April 17, 2017: Optics Express
https://www.readbyqxmd.com/read/28436936/the-u2af1s34f-mutation-induces-lineage-specific-splicing-alterations-in-myelodysplastic-syndromes
#9
Bon Ham Yip, Violetta Steeples, Emmanouela Repapi, Richard N Armstrong, Miriam Llorian, Swagata Roy, Jacqueline Shaw, Hamid Dolatshad, Stephen Taylor, Amit Verma, Matthias Bartenstein, Paresh Vyas, Nicholas C P Cross, Luca Malcovati, Mario Cazzola, Eva Hellström-Lindberg, Seishi Ogawa, Christopher W J Smith, Andrea Pellagatti, Jacqueline Boultwood
Mutations of the splicing factor-encoding gene U2AF1 are frequent in the myelodysplastic syndromes (MDS), a myeloid malignancy, and other cancers. Patients with MDS suffer from peripheral blood cytopenias, including anemia, and an increasing percentage of bone marrow myeloblasts. We studied the impact of the common U2AF1S34F mutation on cellular function and mRNA splicing in the main cell lineages affected in MDS. We demonstrated that U2AF1S34F expression in human hematopoietic progenitors impairs erythroid differentiation and skews granulomonocytic differentiation toward granulocytes...
April 24, 2017: Journal of Clinical Investigation
https://www.readbyqxmd.com/read/28436662/multiconfiguration-pair-density-functional-theory-predicts-spin-state-ordering-in-iron-complexes-with-the-same-accuracy-as-complete-active-space-second-order-perturbation-theory-at-a-significantly-reduced-computational-cost
#10
Liam Wilbraham, Pragya Verma, Donald G Truhlar, Laura Gagliardi, Ilaria Ciofini
The spin-state orderings in nine Fe(II) and Fe(III) complexes with ligands of diverse ligand-field strength were investigated with multiconfiguration pair-density functional theory (MC-PDFT). The performance of this method was compared to that of complete active space second-order perturbation theory (CASPT2) and Kohn-Sham density functional theory. We also investigated the dependence of CASPT2 and MC-PDFT results on the size of the active-space. MC-PDFT reproduces the CASPT2 spin-state ordering, the dependence on the ligand field strength, and the dependence on active space at a computational cost that is significantly reduced as compared to CASPT2...
April 24, 2017: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/28435650/postnatal-transitional-weight-loss-and-adverse-outcomes-in-extremely-premature-neonates
#11
Rita P Verma, Syed Shibli, Eugene Komaroff
The early postnatal weight loss (EPWL) is highly variable in the extremely low birth weight infants (birth weight <1000 g, ELBW). It is reported to be unassociated with adverse outcomes within a range of 3-21% of birth weight. Its wide range might have contributed to this lack of association. The aim of our paper is to study the effects of maximum EPWL, graded as low, medium and large on clinical outcomes in ELBW infants. In a retrospective cohort observational study EPWL was measured as maximum weight loss from birth weight (MWL) in ELBW infants and grouped as low (5-12%) moderate (18...
March 22, 2017: Pediatric Reports
https://www.readbyqxmd.com/read/28435366/comparative-evaluation-of-antimicrobial-efficacy-of-triple-antibiotic-paste-calcium-hydroxide-and-a-proton-pump-inhibitor-against-resistant-root-canal-pathogens
#12
Shibha Mehta, Promila Verma, Aseem Prakash Tikku, Anil Chandra, Rhythm Bains, Gopa Banerjee
OBJECTIVE: The objective of this study is to compare the antimicrobial efficacy of triple antibiotic paste (TAP) and a proton pump inhibitor (PPI) (omeprazole) in combination with calcium hydroxide (CH) against Enterococcus faecalis and Candida albicans. MATERIALS AND METHODS: E. faecalis and C. albicans were subcultured and inoculated at 37° overnight and were treated with different dilutions of TAP, 25 μg/ml (Group 1), CH (Group 2, control), CH 16 mg/ml + omeprazole 2 mg/ml (Group 3a) (CH 16 mg/ml + omeprazole 4 mg)/ml (Group 3b) for 24, 48, and 72 h in sterile uncoated 96-well microtiter plates...
January 2017: European Journal of Dentistry
https://www.readbyqxmd.com/read/28435191/occurrence-of-multidrug-resistant-escherichia-coli-in-groundwater-of-brij-region-uttar-pradesh-and-its-public-health-implications
#13
Barkha Sharma, Parul, A K Verma, Udit Jain, Janaradan K Yadav, Ravneet Singh, Raghvendra Mishra
AIM: The study evaluates the microbial as well as physicochemical pollution of groundwater of Brij region of Uttar Pradesh, a major tourist destination in the country along with estimating the drug resistance evident in the isolated Escherichia coli. MATERIALS AND METHODS: A total of 60 samples of groundwater were collected from six different sites and assessed for physicochemical (pH, color, taste, turbidity, total dissolved solids [TDS], total hardness [TH], chlorides, fluorides, nitrates, and iron) and microbiological parameters (standard plate count [SPC], most probable number test [MPN], E...
March 2017: Veterinary World
https://www.readbyqxmd.com/read/28435058/in-vitro-and-in-vivo-evaluation-of-gastro-retentive-carvedilol-loaded-chitosan-beads-using-gastroplus%C3%A2
#14
Radhakrishnan Praveen, Priya Ranjan Prasad Verma, Jayachandran Venkatesan, Dong-Han Yoon, Se-Kwon Kim, Sandeep Kumar Singh
The objective of present investigation was to develop gastro-retentive controlled release system of carvedilol using biological macromolecule, chitosan. 3(2) full factorial design was adopted for optimization of tripolyphosphate (X1) and curing time (X2). Bead stability in 0.1N HCl, buoyancy duration, density, drug loading, dissolution efficiency and cumulative percentage release at 8th hour were evaluated as dependent variables. The levels of X1 and X2 of optimized formulation having maximum desirability was found to 2...
April 20, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28434617/stem-cell-lineage-infidelity-drives-wound-repair-and-cancer
#15
Yejing Ge, Nicholas C Gomez, Rene C Adam, Maria Nikolova, Hanseul Yang, Akanksha Verma, Catherine Pei-Ju Lu, Lisa Polak, Shaopeng Yuan, Olivier Elemento, Elaine Fuchs
Tissue stem cells contribute to tissue regeneration and wound repair through cellular programs that can be hijacked by cancer cells. Here, we investigate such a phenomenon in skin, where during homeostasis, stem cells of the epidermis and hair follicle fuel their respective tissues. We find that breakdown of stem cell lineage confinement-granting privileges associated with both fates-is not only hallmark but also functional in cancer development. We show that lineage plasticity is critical in wound repair, where it operates transiently to redirect fates...
April 19, 2017: Cell
https://www.readbyqxmd.com/read/28433779/identification-of-new-anti-inflammatory-agents-based-on-nitrosporeusine-natural-products-of-marine-origin
#16
Satish Chandra Philkhana, Abhishek Kumar Verma, Gorakhnath R Jachak, Bibhabasu Hazra, Anirban Basu, D Srinivasa Reddy
Nitrosporeusines A and B are two recently isolated marine natural products with novel skeleton and exceptional biological profile. Interesting antiviral activity of nitrosporeusines and promising potential in curing various diseases, evident from positive data from various animal models, led us to investigate their anti-inflammatory potential. Accordingly, we planned and synthesized nitrosporeusines A and B in racemic as well as enantiopure forms. The natural product synthesis was followed by preparation of several analogues, and all the synthesized compounds were evaluated for in vitro and in vivo anti-inflammatory potential...
April 13, 2017: European Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/28433687/steroid-resistance-of-airway-type-2-innate-lymphoid-cells-ilc2s-from-severe-asthma-the-role-of-thymic-stromal-cell-lymphopoietin-tslp
#17
Sucai Liu, Mukesh Verma, Lidia Michalec, Weimin Liu, Anand Sripada, Donald Rollins, James Good, Yoko Ito, HongWei Chu, Magdalena M Gorska, Richard J Martin, Rafeul Alam
BACKGROUND: ILC2s represent an important type 2 immune cell. Glucocorticoid regulation of human ILC2s is largely unknown. OBJECTIVE: To assess steroid resistance of human blood and airway ILC2s from asthmatic patients and examine its mechanism of induction. METHODS: We studied human blood and lung ILC2s from asthmatic and control subjects by flow cytometry and ELISA. RESULTS: Dexamethasone (Dex) inhibited (P=0.04) CRTH2 and type 2 cytokine expression by blood ILC2s stimulated with IL25 and IL33...
April 19, 2017: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28433618/evidence-based-recommendations-for-insulin-intensification-strategies-after-basal-insulin-in-type-2-diabetes
#18
Sujoy Ghosh, A G Unnikrishnan, Banshi Saboo, Jothydev Kesavadev, S R Aravind, Sarita Bajaj, Rajesh Rajput, Krishna Seshadri, Narsingh Verma, Arvind Gupta, Brij Mohan Makkar, Mihir Saikia, Shailaja Kale, Suresh Damodaran, Ashish Dengra, T K M Eashwar, Anuj Maheshwari, Sharad Pendsey, Sanjeev R Phatak, Surendra Kumar Sharma, Surya Kumar Singh, A Ramachandran, Abdul H Zargar, Shashank R Joshi, Shaukat M Sadikot
Over the time due to progressive nature of diabetes, proactive intensification of the existing insulin therapy becomes imminent as it minimizes patients' exposure to chronic hypo/hyperglycaemia and reduces weight gain while achieving individualized glycaemic targets. This review focuses on the strength of evidence behind various options for intensification, primarily the insulins as also the GLP-1 analogues. The recommendations presented here are meant to serve as a guide for the physician managing type 2 diabetes patients requiring insulin intensification upon failing of basal insulin therapy...
April 5, 2017: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28432588/patterns-of-care-and-outcomes-of-multi-agent-versus-single-agent-chemotherapy-as-part-of-multimodal-management-of-low-grade-glioma
#19
Waqar Haque, Vivek Verma, E Brian Butler, Bin S Teh
For high-risk low-grade gliomas (LGGs), adjuvant radiotherapy (RT) with procarbazine/lomustine/vincristine (PCV) chemotherapy increases overall survival (OS) over RT alone. However, in practice, temozolomide (TMZ) is often used instead of PCV. Using the National Cancer Data Base (NCDB), we provide the first investigation of practice patterns and outcomes of chemoradiotherapy with single-agent chemotherapy (SAC, analogous to TMZ) or multi-agent chemotherapy (MAC, analogous to PCV) for LGG. Patients with high-risk Grade II LGGs were queried in the NCDB...
April 21, 2017: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/28431085/health-status-in-europe-comparison-of-24-urban-areas-to-the-corresponding-10-countries-euro-urhis-2
#20
E M Koster, R de Gelder, F Di Nardo, G Williams, A Harrison, L P van Buren, H Lyshol, L Patterson, C A Birt, J Higgerson, P W Achterberg, A Verma, E J C van Ameijden
: In Europe, over 70% of the population live in urban areas (UAs). Most international comparative health research is done using national level data, as reliable and comparable urban data are often unavailable or difficult to access. This study aims to investigate whether population health is different in UAs compared with their corresponding countries. : Routinely available health-related data were collected by the EURO-URHIS 2 project, for 10 European countries and for 24 UAs within those countries. National and UA level data for 11 health indicators were compared through the calculation of relative difference, and geographical patterns within Europe were investigated using the Mann Whitney U test...
April 18, 2017: European Journal of Public Health
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