keyword
MENU ▼
Read by QxMD icon Read
search

Vidal

keyword
https://www.readbyqxmd.com/read/29221819/cerebellar-alterations-in-a-model-of-down-syndrome-the-role-of-the-dyrk1a-gene
#1
Susana García-Cerro, Verónica Vidal, Sara Lantigua, Maria Teresa Berciano, Miguel Lafarga, Pedro Ramos-Cabrer, Daniel Padro, Noemí Rueda, Carmen Martínez-Cué
Down syndrome (DS) is characterized by a marked reduction in the size of the brain and cerebellum. These changes play an important role in the motor alterations and cognitive disabilities observed in this condition. The Ts65Dn (TS) mouse, the most commonly used model of DS, reflects many DS phenotypes, including alterations in cerebellar morphology. One of the genes that is overexpressed in both individuals with DS and TS mice is DYRK1A/Dyrk1A (dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A), which has been implicated in the altered cerebellar structural and functional phenotypes observed in both populations...
December 5, 2017: Neurobiology of Disease
https://www.readbyqxmd.com/read/29220340/validation-of-the-technological-process-of-the-preparation-milk-by-vidal
#2
L P Savchenko, V A Mishchenko, V A Georgiyants
Validation was performed on the technological process of the compounded preparation "Milk by Vidal" in accordance with the requirements of the regulatory framework of Ukraine. Critical stages of formulation which can affect the quality of the finished preparation were considered during the research. The obtained results indicated that the quality of the finished preparation met the requirements of the State Pharmacopoeia of Ukraine.
November 2017: International Journal of Pharmaceutical Compounding
https://www.readbyqxmd.com/read/29220033/challenges-and-recommendations-for-epigenomics-in-precision-health
#3
Ava C Carter, Howard Y Chang, George Church, Ashley Dombkowski, Joseph R Ecker, Elad Gil, Paul G Giresi, Henry Greely, William J Greenleaf, Nir Hacohen, Chuan He, David Hill, Justin Ko, Isaac Kohane, Anshul Kundaje, Megan Palmer, Michael P Snyder, Joyce Tung, Alexander Urban, Marc Vidal, Wing Wong
No abstract text is available yet for this article.
December 8, 2017: Nature Biotechnology
https://www.readbyqxmd.com/read/29218436/peritoneal-dialysis-and-infants-further-insights-into-a-complicated-relationship
#4
EDITORIAL
Enrico Vidal
Peritoneal dialysis (PD) in infants represents one of the greatest challenges for pediatric nephrologists. Over recent years, positive outcome data described by several multicenter experiences and registry studies have increased the amount of information available to help determine whether to initiate a dialysis program in this high-risk patient population. There is no doubt that the rigorous implementation of strategies aimed at preventing infectious complications may have contributed to reducing the morbidity rate of these patients...
December 7, 2017: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/29218254/bone-microenvironment-has-an-influence-on-the-histological-response-of-osteosarcoma-to-chemotherapy-retrospective-analysis-and-preclinical-modeling
#5
Vincent Crenn, Kevin Biteau, Jérôme Amiaud, Clotilde Dumars, Romain Guiho, Luciano Vidal, Louis-Romée Le Nail, Dominique Heymann, Anne Moreau, François Gouin, Françoise Redini
Osteosarcoma, the most common malignant primary bone tumor, is currently treated with chemotherapy and surgery. The effectiveness of chemotherapy is evaluated by means of histological analysis of tumor necrosis, known as "the Huvos score". However, 25% of the patients initially considered good responders will relapse. In our practice, strong tissue heterogeneity around the residual viable cells of the osteosarcoma is observed, but this is not taken into account by the Huvos score, as it is only an average. The objective is to determine whether heterogeneity in the osteosarcoma's microenvironment can play a role in the histological response to chemotherapy...
2017: American Journal of Cancer Research
https://www.readbyqxmd.com/read/29216827/comparative-genomic-analysis-of-brevibacterium-strains-insights-into-key-genetic-determinants-involved-in-adaptation-to-the-cheese-habitat
#6
Nguyen-Phuong Pham, Séverine Layec, Eric Dugat-Bony, Marie Vidal, Françoise Irlinger, Christophe Monnet
BACKGROUND: Brevibacterium strains are widely used for the manufacturing of surface-ripened cheeses, contributing to the breakdown of lipids and proteins and producing volatile sulfur compounds and red-orange pigments. The objective of the present study was to perform comparative genomic analyses in order to better understand the mechanisms involved in their ability to grow on the cheese surface and the differences between the strains. RESULTS: The genomes of 23 Brevibacterium strains, including twelve strains isolated from cheeses, were compared for their gene repertoire involved in salt tolerance, iron acquisition, bacteriocin production and the ability to use the energy compounds present in cheeses...
December 7, 2017: BMC Genomics
https://www.readbyqxmd.com/read/29216391/prevalence-and-determinants-of-rem-sleep-behavior-disorder-in-the-general-population
#7
José Haba-Rubio, Birgit Frauscher, Pedro Marques-Vidal, Jérôme Toriel, Nadia Tobback, Daniela Andries, Martin Preisig, Peter Vollenweider, Ronald Postuma, Raphaël Heinzer
Study Objectives: REM sleep behavior disorder (RBD) is a parasomnia associated with neurodegenerative synucleinopathies. Its prevalence is largely unknown. This study determined the prevalence and characteristics of RBD in the general population using gold-standard polysomnography. Methods: Full polysomnographic data from 1997 subjects (age=59±11.1 years, 53.6% women) participating in a population-based study (HypnoLaus, Lausanne, Switzerland) were collected. Sleep-related complaints and habits were investigated using various sleep measures including the Munich Parasomnia Screening (MUPS) questionnaire, which includes two questions evaluating complex motor behaviors suggestive of RBD...
December 5, 2017: Sleep
https://www.readbyqxmd.com/read/29212942/factors-leading-to-the-loss-of-natural-elite-control-of-hiv-1-infection
#8
María Pernas, Laura Tarancón-Diez, Esther Rodríguez-Gallego, Josep Gómez, Julia G Prado, Concepción Casado, Beatriz Dominguez-Molina, Isabel Olivares, Maite Coiras, Agathe León, Carmen Rodriguez, Jose Miguel Benito, Norma Rallón, Montserrat Plana, Onofre Martinez-Madrid, Marta Dapena, Jose Antonio Iribarren, Jorge Del Romero, Felipe García, José Alcamí, M Ángeles Muñoz-Fernández, Francisco Vidal, Manuel Leal, Cecilio Lopez-Galindez, Ezequiel Ruiz-Mateos
HIV-1 elite controllers (EC) maintain undetectable viral load (VL) in the absence of antiretroviral treatment. However, these subjects have heterogeneous clinical outcomes including a proportion loosing HIV-1 control over time. In this work we compared, in a longitudinal design, transient EC, analyzed before and after the loss of virological control, versus persistent EC. The aim was to identify factors leading to the loss of natural virological control of HIV-1-infection with a longitudinal retrospective study design...
December 6, 2017: Journal of Virology
https://www.readbyqxmd.com/read/29212276/low-circulating-levels-of-the-mitochondrial-peptide-hormone-shlp2-novel-biomarker-for-prostate-cancer-risk
#9
Jialin Xiao, Lauren Howard, Junxiang Wan, Emily Wiggins, Adriana Vidal, Pinchas Cohen, Stephen J Freedland
Context: Mitochondrial DNA mutations and dysfunction are associated with prostate cancer (PCa). Small humanin-like peptide-2 (SHLP2) is a novel mitochondrial-encoded peptide and an important mitochondrial retrograde signaling molecule. Objective: To determine whether serum SHLP2 concentration is associated with PCa risk and whether associations are race-specific.Design, Setting and Participants: Patients undergoing prostate biopsy were recruited from the Durham Veterans Affairs hospital...
November 7, 2017: Oncotarget
https://www.readbyqxmd.com/read/29209952/correction-to-seom-clinical-guideline-of-diagnosis-and-management-of-lowgrade-glioma-2017
#10
J M Sepúlveda-Sánchez, J Muñoz Langa, M Á Arráez, J Fuster, A Hernández Laín, G Reynés, V Rodríguez González, E Vicente, M Vidal Denis, Ó Gallego
The original version of this article unfortunately contained a mistake. Figure 3 was incorrect.
December 5, 2017: Clinical & Translational Oncology
https://www.readbyqxmd.com/read/29208992/author-correction-intermediate-degrees-of-synergistic-pleiotropy-drive-adaptive-evolution-in-ecological-time
#11
Léa Frachon, Cyril Libourel, Romain Villoutreix, Sébastien Carrère, Cédric Glorieux, Carine Huard-Chauveau, Miguel Navascués, Laurène Gay, Renaud Vitalis, Etienne Baron, Laurent Amsellem, Olivier Bouchez, Marie Vidal, Valérie Le Corre, Dominique Roby, Joy Bergelson, Fabrice Roux
In the version of this Article previously published, there was a typographical error ('4' instead of '2') in the equations relating F ST and effective population size (N e) in the Methods section 'Genome-wide scan for selection based on temporal differentiation'. The correct equations are given below.[Formula: see text] [Formula: see text].
December 5, 2017: Nature Ecology & Evolution
https://www.readbyqxmd.com/read/29208783/clinical-time-required-and-internal-adaptation-in-cavities-restored-with-bulk-fill-composites
#12
Marcos Gabriel Vianna-de-Pinho, Guilherme Ferreira Rego, Marina Lermenn Vidal, Roberta Caroline Bruschi Alonso, Luis Felipe Jochims Schneider, Larissa Maria Cavalcante
AIM: The aim of this study was to compare the restorative time required and the internal adaptation after thermomechanical aging of class I restorations using either the conventional incremental technique or bulk-fill technique. MATERIALS AND METHODS: Cavities (Class I) were prepared on the occlusal surface of human third molars. 40 teeth were divided into four experimental groups according to the restorative technique (n = 10): G1 = 3 mm increment of Surefill SDR Flow + 1 mm Filtek P60; G2 = 3 mm increment of Filtek Bulk-Fill + 1 mm Filtek P60; G3 = Filtek P60 inserted with incremental technique; G4 = 3 mm increment of Filtek Z350 Flow XT + 1 mm increment of Filtek P60...
December 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/29208582/bacterial-fungal-parasitological-and-pathological-analyses-of-abortions-in-small-ruminants-from-2012-2016
#13
P Schnydrig, S Vidal, I Brodard, C Frey, H Posthaus, V Perreten, S Rodriguez-Campos
Abortion in small ruminants presents a clinical and economic problem with legal implications regarding animal health and zoonotic risk by some of the abortive pathogens. Several bacteria, fungi and parasites can cause abortion, but cost-orientated routine diagnostics only cover the most relevant epizootic agents. To cover a broad-range of common as well as underdiagnosed abortifacients, we studied 41 ovine and 36 caprine abortions by Stamp's modification of the Ziehl-Neelsen stain, culture for classical and opportunistic abortive agents, real-time PCR for C...
December 2017: Schweizer Archiv Für Tierheilkunde
https://www.readbyqxmd.com/read/29208561/antibacterial-prophylaxis-with-ciprofloxacin-for-patients-with-multiple-myeloma-and-lymphoma-undergoing-autologous-haematopoietic-cell-transplantation-a-quasi-experimental-single-centre-before-after-study
#14
Moshe Yeshurun, Iuliana Vaxman, Liat Shargian, Dafna Yahav, Jihad Bashara, Oren Pasvolski, Ofir Wolach, Meir Lahav, Ronit Gurion, Hila Magen, Liat Vidal, Corina Herscovici, Anat Peck, Maya Moshe, Michal Sela Navon, Elizabeth Naparstek, Pia Raanani, Uri Rozovski
OBJECTIVES: We aimed to study whether ciprofloxacin prophylaxis reduces infectious complications in patients undergoing autologous haematopoietic cell transplantation (AHCT). METHODS: This is a quasi-experimental, retrospective, before-after study. We compared the incidence of bacterial related complications among 356 patients with multiple myeloma (MM) (n=202) and lymphoma (n=154) who underwent AHCT with (n=177) or without (n=179) ciprofloxacin prophylaxis between 03/2007-10/2012 and between 10/2012-07/2016, respectively at a single centre...
December 2, 2017: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/29206178/around-and-beyond-53bp1-nuclear-bodies
#15
REVIEW
Anne Fernandez-Vidal, Julien Vignard, Gladys Mirey
Within the nucleus, sub-nuclear domains define territories where specific functions occur. Nuclear bodies (NBs) are dynamic structures that concentrate nuclear factors and that can be observed microscopically. Recently, NBs containing the p53 binding protein 1 (53BP1), a key component of the DNA damage response, were defined. Interestingly, 53BP1 NBs are visualized during G1 phase, in daughter cells, while DNA damage was generated in mother cells and not properly processed. Unlike most NBs involved in transcriptional processes, replication has proven to be key for 53BP1 NBs, with replication stress leading to the formation of these large chromatin domains in daughter cells...
December 5, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29202422/dependence-of-samarium-soil-interaction-on-samarium-concentration-implications-for-environmental-risk-assessment
#16
Oriol Ramírez-Guinart, Aitor Salaberria, Miquel Vidal, Anna Rigol
The sorption and desorption behaviour of samarium (Sm), an emerging contaminant, was examined in soil samples at varying Sm concentrations. The obtained sorption and desorption parameters revealed that soil possessed a high Sm retention capacity (sorption was higher than 99% and desorption lower than 2%) at low Sm concentrations, whereas at high Sm concentrations, the sorption-desorption behaviour varied among the soil samples tested. The fractionation of the Sm sorbed in soils, obtained by sequential extractions, allowed to suggest the soil properties (pH and organic matter solubility) and phases (organic matter, carbonates and clay minerals) governing the Sm-soil interaction...
December 1, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/29200836/computerized-cognitive-stimulation-and-engagement-programs-in-older-adults-with-mild-cognitive-impairment-comparing-feasibility-acceptability-and-cognitive-and-psychosocial-effects
#17
Leila Djabelkhir, Ya-Huei Wu, Jean-Sébastien Vidal, Victoria Cristancho-Lacroix, Fabienne Marlats, Hermine Lenoir, Ariela Carno, Anne-Sophie Rigaud
Purpose: Mild cognitive impairment (MCI) is associated with a higher risk of dementia and is becoming a topic of interest for pharmacological and nonpharmacological interventions. With advances in technology, computer-based cognitive exercises are increasingly integrated into traditional cognitive interventions, such as cognitive training. Another type of cognitive intervention involving technology use is cognitive engagement, consisting of involving participants in highly motivational and mentally challenging activities, such as learning to use a form of new digital technology...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/29199581/molecular-dynamics-and-virtual-screening-analysis-of-lanosterol-derivatives-from-ganoderma-medicinal-mushrooms-agaricomycetes-as-selective-ligands-of-human-androgen-receptor
#18
Abraham M Vidal-Limon, Oscar Daniel Luna-Martinez, Fausto Rojas-Durán, Thuluz Meza-Menchaca, Maria Elena Hernández-Aguilar, Angel Trigos, Jorge Suárez-Medellín
Male sex hormones such as testosterone and dihydrotestosterone play important roles in several physiological and pathological processes. The biological activities of the aforementioned metabolites are mediated by the multidomain androgen receptor (AR), which is therefore a well-studied drug target. Ganoderma mushroom lanostanoid extracts have previously been shown to exert antiandrogenic activity; therefore, this work aims to identify which lanostane derivatives might act as selective ligands for AR. Because protein flexibility is of paramount importance for ligand binding, different conformations of AR were sampled to account for binding modes within a ligand binding site, then subjected to virtual screening against a metabolite library...
2017: International Journal of Medicinal Mushrooms
https://www.readbyqxmd.com/read/29198903/canadian-registry-of-implantable-electronic-device-outcomes-longer-term-follow-up-of-the-riata-lead-under-advisory
#19
Ratika Parkash, Bernard Thibault, Francois Philippon, Iqwal Mangat, Benoit Coutu, Matthew Bennett, Eugene Crystal, Jeffrey Healey, Atul Verma, Roopinder Sandhu, Douglas Cameron, Felix Ayala-Paredes, Laurence Sterns, Vidal Essebag, Marcio Sturmer, Pablo Nery, George Wells, Andrew Krahn
BACKGROUND: The Riata lead advisory was announced in 2011 and has posed unique management challenges due to cable externalization and insulation abrasion, in some cases leading to sudden loss of defibrillation. OBJECTIVE: We sought to provide further data on the rate of electrical failure in population of patients with a Riata lead under advisory. METHODS: Using the Canadian Registry of Electronic Device Outcomes, prospective follow up data was collected on 1352 Riata leads under advisory in 17 ICD implantation centers in Canada...
November 30, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29197401/neglected-zoonotic-agents-in-cattle-abortion-tackling-the-difficult-to-grow-bacteria
#20
Sara Vidal, Kristel Kegler, Gilbert Greub, Sebastien Aeby, Nicole Borel, Mark P Dagleish, Horst Posthaus, Vincent Perreten, Sabrina Rodriguez-Campos
BACKGROUND: Coxiella burnetii, Chlamydia abortus and Leptospira spp. are difficult to grow bacteria that play a role in bovine abortion, but their diagnosis is hampered by their obligate intracellular lifestyle (C. burnetii, C. abortus) or their lability (Leptospira spp.). Their importance is based on the contagious spread in food-producing animals, but also as zoonotic agents. In Switzerland, first-line routine bacteriological diagnostics in cattle abortions is regulated by national law and includes only basic screening by staining for C...
December 2, 2017: BMC Veterinary Research
keyword
keyword
58094
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"