N Bellon, S Hadj-Rabia, F Moulin, C Lambe, G Lezmi, F Charbit-Henrion, C Alby, L Le Saché-de Peufeilhoux, S Leclerc-Mercier, A Hadchouel, J Steffann, A Hovnanian, A Lapillonne, C Bodemer
BACKGROUND: Netherton syndrome (NS) is a rare disease caused by SPINK5 mutations, featuring variable skin and hair involvement and, in many cases, allergic manifestations with a risk of lethality, particularly in infants. The clinical management of NS is challenging. OBJECTIVES: To analyse the clinical manifestations of a cohort of infants with NS managed in a reference centre and to draw up recommendations for management. METHODS: We conducted a monocentric analysis of patients with NS...
March 2021: British Journal of Dermatology