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Neonatal hypernatremia dehydration

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https://www.readbyqxmd.com/read/27183555/a-rare-cause-of-retinal-artery-occlusion-in-severe-hypernatremic-dehydration-in-newborns
#1
Pinar Altiaylik Ozer, Emrah Utku Kabatas, Bengi Ece Kurtul, Dilek Dilli, Aysegul Zenciroglu, Nurullah Okumus
Neonatal hypernatremia is an important electrolyte disorder that may have serious complications. It may be a rare and underdiagnosed cause of venous and arterial thrombosis, leading to severe brain damage by cerebral edema and intracranial hemorrhage. Here, the authors present a case of bilateral central retinal artery occlusion in a newborn with severe hypernatremic dehydration who is found to be normal in terms of other causes of retinal arterial thromboembolization. [Ophthalmic Surg Lasers Imaging Retina...
May 1, 2016: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/25449762/-vasopressin-v2-receptor-related-pathologies-congenital-nephrogenic-diabetes-insipidus-and-nephrogenic-syndrome-of-inappropiate-antidiuresis
#2
Denis Morin
Congenital nephrogenic diabetes insipidus is a rare hereditary disease with mainly an X-linked inheritance (90% of the cases) but there are also autosomal recessive and dominant forms. Congenital nephrogenic diabetes insipidus is characterized by a resistance of the renal collecting duct to the action of the arginine vasopressin hormone responsible for the inability of the kidney to concentrate urine. The X-linked form is due to inactivating mutations of the vasopressin 2 receptor gene leading to a loss of function of the mutated receptors...
December 2014: Néphrologie & Thérapeutique
https://www.readbyqxmd.com/read/25271879/central-diabetes-insipidus-alert-for-dehydration-in-very-low-birth-weight-infants-during-the-neonatal-period-a-case-report
#3
Maria Lúcia Silveira Ferlin, Débora Simone Sales, Fábia Pereira Martins Celini, Carlos Eduardo Martinelli Junior
CONTEXT: Central diabetes insipidus (CDI) is a rare cause of hypernatremia during the neonatal period. The diagnosis is particularly difficult in very low birth weight (VLBW) newborns. CASE REPORT: We report on a preterm newborn who presented CDI soon after birth. On the third day of life, signs of dehydration were present despite normal fluid supply. The diuresis rate was 4.4 ml/kg/h. Although the fluid supply was then increased, the dehydration continued, with hypernatremia, normal glycemia, diuresis of 7...
February 2015: São Paulo Medical Journal, Revista Paulista de Medicina
https://www.readbyqxmd.com/read/24630509/congenital-glucose-galactose-malabsorption-a-descriptive-study-of-clinical-characteristics-and-outcome-from-western-saudi-arabia
#4
Omar I Saadah, Sharifa A Alghamdi, Haifa H Sindi, Huda Alhunaitti, Yagoub Y Bin-Taleb, Bakr H Alhussaini
BACKGROUND AND STUDY AIMS: Congenital glucose galactose malabsorption (CGGM) is a rare autosomal recessive disorder caused by a defect in the sodium-coupled transport of glucose and galactose across the intestinal brush border presenting with neonatal diarrhoea. The aim of this study was to report the clinical and laboratory characteristics of patients with CGGM from the Western Saudi Arabia. PATIENTS AND METHODS: This is a retrospective review of CGGM patients in three major hospitals in the city of Jeddah, Saudi Arabia, namely King Abdulaziz University Hospital, King Faisal Specialist Hospital and Research Centre, and Maternity Children Hospital in the period between November 2001 and October 2011...
March 2014: Arab Journal of Gastroenterology: the Official Publication of the Pan-Arab Association of Gastroenterology
https://www.readbyqxmd.com/read/24505569/could-neonatal-hypernatremia-dehydration-influence-hearing-status
#5
Hassan Boskabadi, Farnaz Anvarifar, Navid Nourizadeh
INTRODUCTION: Neonatal hypernatremia dehydration (NHD) is a dangerous condition in neonates, which is accompanied by acute complications (renal failure, cerebral edema, and cerebral hemorrhage) and chronic complications (developmental delay). Children begin learning language from birth, and hearing impairment interferes with this process. We assessed the hearing status of infants with hypernatremia dehydration. MATERIALS AND METHODS: In a case-control study in 110 infants presenting at the Ghaem Hospital (Mashhad, Iran) between 2007 and 2011, we examined the incidence of hearing impairment in infants suffering from hypernatremia dehydration (serum sodium >150 mEq/L) in comparison with infants with normal sodium level (serum sodium ≤150 mEq/L)...
January 2014: Iranian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/23919742/prognostic-value-of-amplitude-integrated-electroencephalography-in-neonates-with-hypernatremic-dehydration
#6
Kadir Şerafettin Tekgunduz, Ibrahim Caner, Zeynep Eras, Ayhan Taştekin, Huseyin Tan, Nurdan Dinlen
OBJECTIVES: Hypernatremic dehydration in neonates is a condition that develops due to inadequate fluid intake and it may lead to cerebral damage. We aimed to determine whether there was an association between serum sodium levels on admission and aEEG patterns and prognosis, as well as any association between aEEG findings and survival rates and long-term prognosis. METHOD: The present study included all term infants hospitalized for hypernatremic dehydration in between January 2010 and May 2011...
May 2014: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/23823259/what-is-the-safe-approach-for-neonatal-hypernatremic-dehydration-a-retrospective-study-from-a-neonatal-intensive-care-unit
#7
Fatih Bolat, Mehmet Burhan Oflaz, Ahmet Sami Güven, Göktuğ Özdemir, Demet Alaygut, Melih Timuçin Doğan, Füsun Dilara Içağasoğlu, Ömer Cevit, Asim Gültekin
OBJECTIVES: The aims of this study were to evaluate the prevalence, complications, and mortality of hypernatremic dehydration in neonates and to compare the effect of correction rate at 48 hours on mortality and on neurological outcome in the short term. METHODS: This retrospective study was conducted between January 2007 and 2011 in the neonatal intensive care unit. Term neonates were included. The patients were grouped as follows: group 1 = 150 to 160 mmol/L, group 2 = 161 to 170 mmol/L and group 3 = 171 to 189 mmol/L...
July 2013: Pediatric Emergency Care
https://www.readbyqxmd.com/read/23805991/comparison-of-oral-and-intravenous-fluid-therapy-in-newborns-with-hypernatremic-dehydration
#8
COMPARATIVE STUDY
Aydin Erdemir, Zelal Kahramaner, Hese Cosar, Ebru Turkoglu, Ali Kanik, Sumer Sutcuoglu, Esra Arun Ozer
OBJECTIVE: To evaluate the efficacy and complications of oral and intravenous fluid therapy in newborns with hypernatremic dehydration. METHODS: A total of 75 term and near-term (>35 weeks) neonates with hypernatremic dehydration (Na ≥ 150 mmol/L) were included in this retrospective study. The patients were divided into two groups according to therapy approach for rehydration (breast milk-oral formula and intravenous fluid). The decline in sodium concentration (<0...
March 2014: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/23123669/acute-peritoneal-dialysis-in-neonates-with-acute-kidney-injury-and-hypernatremic-dehydration
#9
Nurdan Yildiz, Müferet Erguven, Metin Yildiz, Tutku Ozdogan, Pinar Turhan
OBJECTIVE: We aimed to evaluate the efficacy of acute peritoneal dialysis (PD) and clinical outcomes in neonates with acute kidney injury (AKI) and hypernatremic dehydration. ♢ METHODS: The medical records of 15 neonates with AKI and hypernatremic dehydration who were treated with acute PD were reviewed. The diagnoses were AKI with hypernatremic dehydration with or without sepsis in 13 patients and AKI with hypernatremia and congenital nephropathy in 2 patients...
May 2013: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
https://www.readbyqxmd.com/read/22970682/a-fatal-case-of-hypernatraemic-dehydration-in-a-neonate
#10
Eveline Staub, Barry Wilkins
Problems with lactation can result in hypernatraemic dehydration in the neonate, with potentially severe adverse consequences. This is illustrated in this fatal case of a 10 day old neonate who presented with excessive hypernatraemic dehydration due to insufficient breast milk intake, resulting in cerebral sinus vein thrombosis with cerebral haemorrhage and infarction. Differential diagnosis included excessive sodium intake (through inappropriately mixed formula or house remedies or through hyperaldosteronism) and high water deficit (renal or gastrointestinal losses, nephrogenic or central diabetes insipidus), all of which were ruled out by specific investigations or history...
September 2012: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/22914558/rotavirus-disease-in-germany-a-prospective-survey-of-very-severe-cases
#11
Sonu Shai, Ruy Perez-Becker, Carl-Heinz Wirsing von König, Rüdiger von Kries, Ulrich Heininger, Johannes Forster, Hans-Iko Huppertz, Reinhard Roos, Ulrich Göbel, Tim Niehues
OBJECTIVE: Rotavirus (RV) gastroenteritis is a notifiable disease in Germany. The reports to the authorities contain few data concerning the severity of disease. The aims of this study were to determine incidence and outcome of very severe cases of RV disease. METHODS: Cases of very severe RV disease were collected by the German Paediatric Surveillance Unit for rare diseases (Erhebungseinheit für seltene pädiatrische Erkrankungen in Deutschland) using anonymous questionnaires based on hospitalized patients between April 2009 and March 2011...
February 2013: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/22665862/severe-hypernatremic-dehydration-associated-with-cerebral-venous-and-aortic-thrombosis-in-the-neonatal-period
#12
Mohammed Hbibi, Sana Abourazzak, Abdeladim Babakhouya, Meryem Boubou, Samir Atmani, Siham Tizniti, Abdelhak Bouharrou
Severe neonatal hypernatremia is an important electrolyte disorder that has serious effects. Cerebral venous thrombosis and aortic thrombosis are relatively rare in severe neonatal hypernatremic dehydration. The authors report a case of cerebral venous thrombosis, associated with aortic thrombosis revealed by dehydration in a 9-day-old boy. Diagnostic was performed using Doppler ultrasound and imaging techniques. Thrombosis was resolved after anticoagulation treatment with low-molecular weight heparin for 1 month, and then was substituted by oral anticoagulant...
2012: BMJ Case Reports
https://www.readbyqxmd.com/read/22237234/hypernatremic-dehydration-due-to-lactation-failure-in-an-exclusively-breastfed-neonate
#13
Syed Ahmed Zaki, Jayashree Mondkar, Preeti Shanbag, Rahul Verma
We report a 13-day-old exclusively breastfed neonate, admitted with a history of fever, poor feeding, lethargy and decreased urine output. The mother had history of lactation failure. The neonate had severe hypernatremia, acute renal failure and metabolic acidosis. Renal ultrasound was normal, but the sodium level in mother's milk was 96 mEq/L (normal 7 ± 2 mEq/L). The neonate required peritoneal dialysis on the second day of admission. The biochemical investigations gradually returned to normal and the neonate was discharged on day 12 of admission...
January 2012: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/21968248/severe-hypernatremic-dehydration-and-metabolic-acidosis-due-to-neonatal-intestinal-microvillus-inclusion-disease
#14
Shaneela Shahid, Douglas D Fraser, David K Driman, Kevin C Bax
Neonatal microvillus inclusion disease (MID) is a congenital secretory diarrhea diagnosed by morphological enterocyte abnormalities on histology. The secretory diarrhea associated with MID occurs within the first few hours of birth and is exacerbated by enteral feeding. Affected newborns will die of dehydration and acid-base disturbances if MID is not rapidly recognized and treated with massive intravenous fluid replacement and gut rest. We report a case of a 4-day-old neonate presenting with 18% weight loss, hypernatremic dehydration and metabolic acidosis...
2012: Neonatology
https://www.readbyqxmd.com/read/21917222/-severe-dehydration-in-a-newborn-following-ambulatory-birth
#15
Lisbeth Marianne Thøstesen, Jesper Fenger-Grøn
A nine day-old girl was hospitalised because of breast-feeding problems and life-threatening hypernatremic dehydration; weight loss was 30% of birth weight and s-Na 187 mmol/l. The question is raised whether there could be an association to the current changes in the perinatal health care in Denmark. The case emphasizes the necessity of a sufficient safety net beneath the newborn children in order to minimise the risk of breast-feeding problems and re-hospitalizing. Neonatal problems such as marked weight loss, dehydration, hypernatremia and marked jaundice are potentially preventable...
September 12, 2011: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/21541645/peripheral-gangrene-in-a-breast-fed-neonate-is-hypernatremic-dehydration-the-cause
#16
Shivani Dogra, Sunil K Agrawal, Ravul Jindal, Deepti Suri, Jasmina Ahluwalia, Surjit Singh
Hypernatremic dehydration in breast fed neonates is a rare but increasingly recognized problem. If not identified early, it may lead to potentially life threatening complications. The authors describe a neonate who developed thrombosis and lower limb ischemia secondary to hypernatremic dehydration. Peripheral gangrene, as a result of hypernatremic dehydration is extremely uncommon and has rarely been reported before.
December 2011: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/21280532/prevalence-of-significant-weight-loss-and-hypernatremia-in-breast-feeding-jaundice-infants-readmitted-to-phramongkutklao-hospital-within-1-month-of-age
#17
Nithipun Suksumek, Tanin Pirunnet, Sangkae Chamnanvanakij, Preyapan Saengaroon
BACKGROUND: Neonatal jaundice, especially breast feeding jaundice is the most common cause of neonatal re-admission within the first month of life. Good maternal support and closed follow-up of newborn infants can promote successful breast feeding without causing any complications. OBJECTIVE: To determine the rate of significant weight loss and hypernatremia in infants with breast feeding jaundice readmitted to Phramongkutklao Hospital within 1 month of age. MATERIAL AND METHOD: Cross-sectional descriptive study was conducted in infants of gestational age > or = 35 weeks and birth weight > or = 2,000 grams who had breast feeding jaundice readmitted between January, 1st and December 31st, 2008...
November 2010: Journal of the Medical Association of Thailand, Chotmaihet Thangphaet
https://www.readbyqxmd.com/read/20822332/neonatal-outcomes-in-a-population-of-late-preterm-infants
#18
COMPARATIVE STUDY
S Picone, P Paolillo
The late-preterm infants are a group of premature steadily increasing, different from term infants as immature in terms of respiratory, metabolic, neurological, and immunological features. They may present at birth and during the first week of life various diseases and brain lesions echographically evident. We analyzed the neonatal outcomes of 417 late-preterm infants, born in our Department of Neonatology in a period of two and a half years, evaluating respiratory problems (RDS, transient tachypnea, pneumonia, pneumothorax, and apnea), metabolic problems (hypoglycemia, hypomagnesemia, hypo-hypernatremia, dehydration, hypocalcemia, and hyperbilirubinemia), infections, neurological symptoms associated with electrolyte disturbances, the disease patterns observed by ultrasound examination of the brain, the kidney ultrasound images, genital malformations...
October 2010: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/20805072/neonatal-hypernatremia-and-dehydration-in-infants-receiving-inadequate-breastfeeding
#19
Hassan Boskabadi, Gholamali Maamouri, Mansour Ebrahimi, Majid Ghayour-Mobarhan, Habib Esmaeily, Amirhossein Sahebkar, Gordon A A Ferns
INTRODUCTION: Neonatal hypernatermic dehydration (NHD) is a potentially very serious condition, which has been reported to occur in infants who have breast feeding problems in the first week of the life. This study looked at the incidence, risk factors, clinical symptoms and complications of NHD in healthy breastfed term neonates. METHODS: A prospective case-control study was conducted on 53 neonates with serum sodium concentrations of >or=150 mmol/L (as the case group) who were recruited between June 2006 and June 2007 from the Ghaem hospital (Mashhad, Iran) to investigate the relationship between NHD and breastfeeding...
2010: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/20016914/severe-hypernatremia-in-newborns-due-to-salting
#20
Erdal Peker, Ercan Kirimi, Oguz Tuncer, Abdullah Ceylan
The aim of this study was to evaluate the etiology, clinical, and laboratory findings and prognostic features of life-threatening hypernatremic newborns secondary to salting. Ten severely hypernatremic newborns (four females) with a mean age of 6.5 +/- 2.6 days were followed up. Nine of them were full term, and one was preterm. It was noticeable that 60% of them were small for gestational age. In the laboratory investigation, five uremias were detected. It was interesting to find in the etiologic history that 40% of the patients had been salted just after birth...
July 2010: European Journal of Pediatrics
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