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Rotator cuff volumes

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https://www.readbyqxmd.com/read/29874950/partial-width-injuries-of-the-rat-rotator-cuff-heal-with-fibrosis
#1
Elisabeth A Lemmon, Ryan C Locke, Adrianna K Szostek, Elahe Ganji, Megan L Killian
PURPOSE: Identify the healing outcomes following a partial-width, full-thickness injury to the rotator cuff tendon-bone attachment and establish if the adult attachment can regenerate the morphology of the healthy attachment. HYPOTHESIS: We hypothesized that a partial-width injury to the attachment would heal via fibrosis and bone remodeling, resulting in increased cellularity and extracellular matrix deposition, reduced bone volume, osteoclast presence, and decreased collagen organization compared to shams...
June 6, 2018: Connective Tissue Research
https://www.readbyqxmd.com/read/29790618/intratendinous-injection-of-autologous-adipose-tissue-derived-mesenchymal-stem-cells-for-the-treatment-of-rotator-cuff-disease-a-first-in-human-trial
#2
Chris H Jo, Jee Won Chai, Eui Cheol Jeong, Sohee Oh, Paul S Kim, Jeong Yong Yoon, Kang Sup Yoon
Despite relatively good results of current symptomatic treatments for rotator cuff disease, there has been an unmet need for fundamental treatments to halt or reverse the progress of disease. The purpose of this study was to assess the safety and efficacy of intratendinous injection of autologous adipose-tissue derived MSCs (AD MSCs) in patients with rotator cuff disease. The first part of the study consists of 3 dose-escalation cohorts; the low- (1.0x107 cells), mid- (5.0x107 ), and high-dose (1.0x108 ) groups with 3 patients each for the evaluation of the safety and tolerability...
May 23, 2018: Stem Cells
https://www.readbyqxmd.com/read/29759907/mechanical-and-imaging-evaluation-of-the-effect-of-sutures-on-tendons-tape-sutures-are-protective-to-suture-pulling-through-tendon
#3
Yohei Ono, Denis A Joly, Gail M Thornton, Ian K Y Lo
BACKGROUND: High-strength sutures, including #2 and tape-type, are popular when performing arthroscopic rotator cuff repair. Although the most common mechanism of anatomic failure of rotator cuff repair is suture pulling through tendon, the effect of sutures on the suture-tendon interface has rarely been investigated. We evaluated the effect of commercially available modern high-strength standard #2 and tape-type sutures on tendon. METHODS: Isolated sutures (FiberTape, #2 FiberWire [Arthrex Inc...
May 11, 2018: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/29759905/analysis-of-4063-complications-of-shoulder-arthroplasty-reported-to-the-us-food-and-drug-administration-from-2012-to-2016
#4
Jeremy S Somerson, Jason E Hsu, Moni B Neradilek, Frederick A Matsen
BACKGROUND: Most of the literature on shoulder arthroplasty failure comes from high-volume centers. These reports tend to exclude the experience of community orthopedic surgeons, who perform most of the shoulder joint replacements. METHODS: We analyzed the failure reports mandated by the US Food and Drug Administration for all hospitals. Each reported event from 2012 to 2016 was characterized by implant, failure mode, and year of surgery. RESULTS: For the 1673 anatomic arthroplasties, the most common failure modes were glenoid component failure (20...
May 11, 2018: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/29754845/do-magnetic-resonance-imaging-and-computed-tomography-provide-equivalent-measures-of-rotator-cuff-muscle-size-in-glenohumeral-osteoarthritis
#5
Peter N Chalmers, Lindsay Beck, Irene Stertz, Alexander Aleem, Jay D Keener, Heath B Henninger, Robert Z Tashjian
BACKGROUND: Rotator cuff muscle volume is associated with outcomes after cuff repair and total shoulder arthroplasty. Muscle area on select magnetic resonance imaging (MRI) slices has been shown to be a surrogate for muscle volume. The purpose of this study was to determine whether computed tomography (CT) provides an equivalent measurement of cuff muscle area to a previously validated MRI measurement. METHODS: We included 30 patients before they were undergoing total shoulder arthroplasty with both preoperative CT and MRI scans performed within 30 days of one another at 1 institution using a consistent protocol...
May 10, 2018: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/29687149/shoulder-muscle-volume-and-fat-content-in-healthy-adult-volunteers-quantification-with-dixon-mri-to-determine-the-influence-of-demographics-and-handedness
#6
Pascal S Kälin, Rebecca J Crawford, Magda Marcon, Andrei Manoliu, Samy Bouaicha, Michael A Fischer, Erika J Ulbrich
OBJECTIVE: We aimed to provide mean values for fat-fraction and volume for full-length bilateral rotator cuff and deltoid muscles in asymptomatic adults selected on the basis of their good musculoskeletal and systemic health, and to understand the influence of gender, age, and arm dominance. MATERIALS AND METHODS: Seventy-six volunteers aged 20 to 60 years who were screened for normal BMI and high general health were included in the study. MRI was performed at 3 Tesla using three-point DIXON sequences...
April 23, 2018: Skeletal Radiology
https://www.readbyqxmd.com/read/29628689/going-forward-with-reverse-shoulder-arthroplasty
#7
REVIEW
Keshav Singhal, Rammohan R
Rotator cuff is a vital structure of glenohumeral joint, the dysfunction of which leads to debilitating pain and restricted movement. Arthroplasty using unconstrained anatomical prosthesis for treating these conditions have not been successful in the past. Reverse Shoulder Arthroplasty (RSA) is a novel technique specifically designed to address end stage glenohumeral arthritis in rotator cuff deficient joint. Short and mid-term studies have demonstrated a significant improvement in pain and range of motion of the shoulder joint...
January 2018: Journal of Clinical Orthopaedics and Trauma
https://www.readbyqxmd.com/read/29558167/what-is-the-appropriate-reference-for-evaluating-the-recovery-of-supraspinatus-muscle-atrophy-after-arthroscopic-rotator-cuff-repair-the-occupation-ratio-of-the-supraspinatus-may-change-after-rotator-cuff-repair-without-volumetric-improvement
#8
Tsuyoshi Sasaki, Hitoshi Shitara, Atsushi Yamamoto, Noritaka Hamano, Tsuyoshi Ichinose, Daisuke Shimoyama, Tsutomu Kobayashi, Toshihisa Osawa, Yoshito Tsushima, Kenji Takagishi, Hirotaka Chikuda
BACKGROUND: Supraspinatus muscle atrophy is typically assessed by the occupation ratio of the cross-sectional area of the muscle belly to the supraspinatus fossa at the medial border of the coracoid process in a slice along the oblique-sagittal plane on MRI. Previous studies have shown that the occupation ratio of the supraspinatus changed soon after rotator cuff repair compared with before surgery. However, no studies have examined the perioperative change in the muscle volume assessed with 3-dimensional measurement...
May 2018: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29533161/polydeoxyribonucleotide-injection-in-the-patients-with-partial-thickness-tear-of-supraspinatus-tendon-a-prospective-and-pilot-study-using-ultrasound
#9
Hyun-Kyung Do, Joong-Hoon Lee, Jae-Young Lim
OBJECTIVE: Polydeoxyribonucleotide as adenosine receptor (A2A ) agonist has been used in plastic surgery and dermatology related to its regenerative property. The aim of this pilot study is to evaluate the safety and efficacy of polydeoxynucleotide injection in patients with rotator cuff tears by a variety of outcomes including pain, disability, physical performance test, and ultrasonography (US). METHODS: Seventeen patients (9 men, 8 women, age: 57.9 ± 9.1) with partial-thickness tear of supraspinatus tendon were evaluated in a prospective, open-label, and pre-and-post study...
May 2018: Physician and Sportsmedicine
https://www.readbyqxmd.com/read/29423865/short-term-outcomes-of-subacromial-injection-of-combined-corticosteroid-with-low-volume-compared-to-high-volume-local-anesthetic-for-rotator-cuff-impingement-syndrome-a-randomized-controlled-non-inferiority-trial
#10
Manusak Boonard, Sermsak Sumanont, Alisara Arirachakaran, Punyawat Apiwatanakul, Artit Boonrod, Wichan Kanchanatawan, Jatupon Kongtharvonskul
BACKGROUND: In symptomatic tendinosis, a corticosteroid injection into the subacromial space is a palliative treatment option. This study compares high volumes (10 cc) of local anesthetic (LA) combined with triamcinolone acetate (TA) with low volumes (4 cc) of LA combined with TA to see whether the latter would provide similar pain, function and complication outcomes for subacromial injections in patients with impingement syndrome. MATERIALS AND METHODS: This single-center, randomized, single-blind, non-inferiority trial included patients with shoulder pain and positive multiple clinical tests supporting the diagnosis of impingement syndrome...
February 8, 2018: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/29311489/retained-myogenic-potency-of-human-satellite-cells-from-torn-rotator-cuff-muscles-despite-fatty-infiltration
#11
Masashi Koide, Yoshihiro Hagiwara, Masahiro Tsuchiya, Makoto Kanzaki, Hiroyasu Hatakeyama, Yukinori Tanaka, Takashi Minowa, Taro Takemura, Akira Ando, Takuya Sekiguchi, Yutaka Yabe, Eiji Itoi
Rotator cuff tears (RCTs) are a common shoulder problem in the elderly that can lead to both muscle atrophy and fatty infiltration due to less physical load. Satellite cells, quiescent cells under the basal lamina of skeletal muscle fibers, play a major role in muscle regeneration. However, the myogenic potency of human satellite cells in muscles with fatty infiltration is unclear due to the difficulty in isolating from small samples, and the mechanism of the progression of fatty infiltration has not been elucidated...
January 2018: Tohoku Journal of Experimental Medicine
https://www.readbyqxmd.com/read/29304956/editorial-commentary-superior-capsule-reconstruction-with-dermal-allograft-effective-marketing-or-the-real-deal
#12
EDITORIAL
Timothy S Leroux
The young patient with a massive, irreparable rotator cuff tear is a challenging problem. Not only is this patient population demanding, but of the few surgical options that exist to manage this problem, each have their own unique limitations; as such, the orthopaedic community continues to search for a treatment that maximizes outcome and durability, while minimizing risk and preserving the native shoulder. Over the past few years, there has been considerable interest in a new surgical technique: the superior capsule reconstruction (SCR)...
January 2018: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29050856/the-relationship-between-age-rotator-cuff-integrity-and-osseous-microarchitecture-of-greater-tuberosity-where-should-we-put-anchor
#13
Erica Kholinne, Hyun Joo Lee, Sung Jung Kim, So Hyun Park, In-Ho Jeon
OBJECTIVE: The aim of this study was to compare the microarchitecture of the greater tuberosity with or without rotator cuff tear and to obtain optimum location for anchor screw insertion for rotator cuff repair. METHODS: Twenty-five humeral heads were harvested from 13 male cadavers of mean age 58.4 years, including 6 humeri with rotator cuff tear and 19 intact humeri. Six regions of interest (proximal, intermediate, and distal zones of the superficial and deep regions) were divided into the anterior (G1), middle (G2), and posterior (G3) areas of the greater tuberosity...
January 2018: Acta Orthopaedica et Traumatologica Turcica
https://www.readbyqxmd.com/read/28872895/hyaluronic-acid-accelerates-tendon-to-bone-healing-after-rotator-cuff-repair
#14
Hirokazu Honda, Masafumi Gotoh, Tomonoshin Kanazawa, Hiroki Ohzono, Hidehiro Nakamura, Keisuke Ohta, Kei-Ichiro Nakamura, Kanji Fukuda, Takeshi Teramura, Takashi Hashimoto, Shigeki Shichijo, Naoto Shiba
BACKGROUND: There is growing evidence that the subacromial injection of hyaluronic acid (HA) is effective for pain relief in rotator cuff tears; however, its effect on tendon-to-bone healing remains unknown. PURPOSE: To examine the effect of HA on the chondrogenesis of mesenchymal stem cells (MSCs) in vitro and on tendon-to-bone healing in a rotator cuff repair model. STUDY DESIGN: Controlled laboratory study. METHODS: Bilateral complete tears of the infraspinatus tendon were made in rabbits and subsequently repaired...
December 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28822641/clinical-and-radiographic-outcomes-with-assessment-of-the-learning-curve-in-arthroscopically-assisted-latissimus-dorsi-tendon-transfer-for-irreparable-posterosuperior-rotator-cuff-tears
#15
Kotaro Yamakado
PURPOSE: To evaluate the clinical results of an arthroscopy-assisted latissimus dorsi tendon transfer (aLD) for irreparable posterosuperior cuff tears as a primary surgery. The secondary aim of this study was to quantify the learning curve using the log-linear model. We hypothesized that aLD significantly improved shoulder function and that there was consistent reduction of the operative time in support of a learning-curve effect. METHODS: After the arthroscopic partial repair was completed, the latissimus dorsi tendon was harvested via axillary mini-open incision and fixed with a knotless anchor arthroscopically...
December 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/28669466/editorial-commentary-volume-and-outcome-100%C3%A2-years-of-perspective-on-value-from-e-a-codman-to-m-e-porter
#16
EDITORIAL
Jon J P Warner, Laurence D Higgins
Outcome is the numerator for the value equation, with the denominator being cost; measurement of each is essential to determine the most effective care. With regard to both total shoulder arthroplasty and rotator cuff repair, outcomes of low (vs high) volume providers are associated with longer hospital stay, longer length of operating room time, increased hospital complications, and cost. This suggests that volume thresholds are a key to providing greater value. However, this effect can be modified through systematic efforts to measure outcome and thus improve...
July 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/28642649/allogeneic-platelet-rich-plasma-for-rotator-cuff-repair
#17
Chris Hyunchul Jo, Ji Sun Shin, Seung Yeon Lee, Sue Shin
OBJECTIVE: To investigate the safety and efficacy of allogeneic platelet-rich plasma (PRP) in rotator cuff repair . METHODS: Seventeen patients with a full-thickness rotator cuff tear were included. Ten patients underwent arthroscopic rotator cuff repair with allogeneic, and seven patients with autologous PRP. Three PRP gels in a volume 3 ml each were applied between the torn end and the greater tuberosity. Clinical outcomes were assessed preoperatively and at a minimum of 2 years after surgery...
January 2017: Acta Ortopedica Brasileira
https://www.readbyqxmd.com/read/28586631/tgf-%C3%AE-1-improves-biomechanical-strength-by-extracellular-matrix-accumulation-without-increasing-the-number-of-tenogenic-lineage-cells-in-a-rat-rotator-cuff-repair-model
#18
Hitoshi Arimura, Chisa Shukunami, Takuya Tokunaga, Tatsuki Karasugi, Nobukazu Okamoto, Takuya Taniwaki, Hidetoshi Sakamoto, Hiroshi Mizuta, Yuji Hiraki
BACKGROUND: Transforming growth factor β1 (TGF-β1) positively regulates the tenogenic marker genes scleraxis ( Scx) and tenomodulin ( Tnmd) in mesenchymal progenitors in vitro. However, little is known about the effect of TGF-β1 on the expression of tenogenic markers during rotator cuff (RC) healing in rats. HYPOTHESIS: TGF-β1 improves the biomechanical properties and histological maturity of reparative tissue in a rat RC repair model by stimulating the growth of tenogenic cells...
August 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28581816/serial-changes-in-3-dimensional-supraspinatus-muscle-volume-after-rotator-cuff-repair
#19
Seok Won Chung, Kyung-Soo Oh, Sung Gyu Moon, Na Ra Kim, Ji Whan Lee, Eungjune Shim, Sehyung Park, Youngjun Kim
BACKGROUND: There is considerable debate on the recovery of rotator cuff muscle atrophy after rotator cuff repair. PURPOSE: To evaluate the serial changes in supraspinatus muscle volume after rotator cuff repair by using semiautomatic segmentation software and to determine the relationship with functional outcomes. STUDY DESIGN: Case series; Level of evidence, 4. METHODS: Seventy-four patients (mean age, 62.8 ± 8.8 years) who underwent arthroscopic rotator cuff repair and obtained 3 consecutive (preoperatively, immediately postoperatively, and later postoperatively [≥1 year postoperatively]) magnetic resonance imaging (MRI) scans having complete Y-views were included...
August 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28574610/costamere-protein-expression-and-tissue-composition-of-rotator-cuff-muscle-after-tendon-release-in-sheep
#20
Severin Ruoss, Christoph B Möhl, Mario C Benn, Brigitte von Rechenberg, Karl Wieser, Dominik C Meyer, Christian Gerber, Martin Flück
Previous studies suggested that degradation of contractile tissue requires cleavage of the costamere, a structural protein complex that holds sarcomeres in place. This study examined if costamere turnover is affected by a rotator cuff tear in a previously established ovine model. We found the activity of focal adhesion kinase (FAK), a main regulator of costamere turnover, was unchanged at 2 weeks but decreased by 27% 16 weeks after surgical release of the infraspinatus tendon. This was accompanied by cleavage of the costamere protein talin into a 190 kDa fragment while full length talin remained unchanged...
January 2018: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
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