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https://www.readbyqxmd.com/read/28738287/perceived-stress-and-poly-tobacco-product-use-across-adolescence-patterns-of-association-and-gender-differences
#1
Adam M Leventhal, Robert Urman, Jessica L Barrington-Trimis, Nicholas I Goldenson, Katia Gallegos, Chih Ping Chou, Kejia Wang, Kiros Berhane, Tess Boley Cruz, Mary Ann Pentz, Jennifer Unger, Rob S McConnell
Perceived stress-an endophenotype indicative of the tendency to appraise stress as frequent, unpredictable and unmanageable-is associated with adolescent cigarette smoking. It is unclear whether this association: (1) extends to alternative tobacco products, like electronic cigarettes and hookah (tobacco water pipe), which are increasingly popular among youth, and (2) differs by gender. In this report, data were drawn from a population-based longitudinal cohort of youth in Southern California. Perceived stress was assessed at baseline (7th or 8th grade; 2010)...
November 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/28654986/association-between-initial-use-of-e-cigarettes-and-subsequent-cigarette-smoking-among-adolescents-and-young-adults-a-systematic-review-and-meta-analysis
#2
REVIEW
Samir Soneji, Jessica L Barrington-Trimis, Thomas A Wills, Adam M Leventhal, Jennifer B Unger, Laura A Gibson, JaeWon Yang, Brian A Primack, Judy A Andrews, Richard A Miech, Tory R Spindle, Danielle M Dick, Thomas Eissenberg, Robert C Hornik, Rui Dang, James D Sargent
Importance: The public health implications of e-cigarettes depend, in part, on whether e-cigarette use affects the risk of cigarette smoking. Objective: To perform a systematic review and meta-analysis of longitudinal studies that assessed initial use of e-cigarettes and subsequent cigarette smoking. Data Sources: PubMed, EMBASE, Cochrane Library, Web of Science, the 2016 Society for Research on Nicotine and Tobacco 22nd Annual Meeting abstracts, the 2016 Society of Behavioral Medicine 37th Annual Meeting & Scientific Sessions abstracts, and the 2016 National Institutes of Health Tobacco Regulatory Science Program Conference were searched between February 7 and February 17, 2017...
August 1, 2017: JAMA Pediatrics
https://www.readbyqxmd.com/read/28623880/associations-between-anhedonia-and-marijuana-use-escalation-across-mid-adolescence
#3
Adam M Leventhal, Junhan Cho, Matthew D Stone, Jessica L Barrington-Trimis, Chih-Ping Chou, Steven Y Sussman, Nathaniel R Riggs, Jennifer B Unger, Janet Audrain-McGovern, David R Strong
BACKGROUND AND AIMS: Anhedonia-a transdiagnostic psychopathological trait indicative of inability to experience pleasure-could lead to and result from adolescent marijuana use, yet this notion has not been tested. This study aimed to estimate the association of: (1) anhedonia at age 14 with rate of change in marijuana use over an 18-month follow-up, and (2) marijuana use at age 14 with rate of change in anhedonia over follow-up. Secondary aims were to test whether gender, baseline marijuana use history and peer marijuana use moderated these associations...
June 17, 2017: Addiction
https://www.readbyqxmd.com/read/28371890/type-of-e-cigarette-device-used-among-adolescents-and-young-adults-findings-from-a-pooled-analysis-of-8-studies-of-2-166-vapers
#4
Jessica L Barrington-Trimis, Laura A Gibson, Bonnie Halpern-Felsher, Melissa B Harrell, Grace Kong, Suchitra Krishnan-Sarin, Adam M Leventhal, Alexandra Loukas, Rob McConnell, Scott R Weaver
Background: A recent study of adult smokers who vape found that disposable/cigalike electronic (e-) cigarette devices were more commonly used than later generation devices. However, whether these trends reflect patterns among adolescents and young adults, many of whom have limited or no history of combustible cigarette use, has not been studied. Methods: Participants were drawn from 8 locally, regionally, and U.S. nationally representative studies. Surveys took place between Fall 2014 and Spring 2016; participants were residents of California (3 studies), Texas (2 studies), Connecticut (1 study), or randomly selected from the United States population (2 studies)...
March 22, 2017: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/27825000/association-of-e-cigarette-vaping-and-progression-to-heavier-patterns-of-cigarette-smoking
#5
LETTER
Adam M Leventhal, Matthew D Stone, Nafeesa Andrabi, Jessica Barrington-Trimis, David R Strong, Steve Sussman, Janet Audrain-McGovern
No abstract text is available yet for this article.
November 8, 2016: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/27806211/electronic-cigarette-use-and-respiratory-symptoms-in-adolescents
#6
Rob McConnell, Jessica L Barrington-Trimis, Kejia Wang, Robert Urman, Hanna Hong, Jennifer Unger, Jonathan Samet, Adam Leventhal, Kiros Berhane
RATIONALE: Rates of adolescent electronic (e-) cigarette use are increasing, but there has been little study of the chronic effects of use. Components of e-cigarette aerosol have known pulmonary toxicity. OBJECTIVES: To investigate the associations of e-cigarette use with chronic bronchitis symptoms and wheeze in an adolescent population. METHODS: Associations of self-reported use of e-cigarettes with chronic bronchitic symptoms (chronic cough, phlegm, or bronchitis) and of wheeze in the previous 12 months were examined in 2,086 Southern California Children's Health Study participants completing questionnaires in 11th and 12th grade in 2014...
April 15, 2017: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/27778348/trends-in-childhood-leukemia-incidence-over-two-decades-from-1992-to-2013
#7
Jessica L Barrington-Trimis, Myles Cockburn, Catherine Metayer, W James Gauderman, Joseph Wiemels, Roberta McKean-Cowdin
Incidence rates of childhood leukemia in the United States have steadily increased over the last several decades, but only recently have disparities in the increase in incidence been recognized. In the current analysis, Surveillance, Epidemiology and End Results (SEER) data were used to evaluate recent trends in the incidence of childhood leukemia diagnosed at age 0-19 years from 1992 to 2013, overall and by age, race/ethnicity, gender and histologic subtype. Hispanic White children were more likely than non-Hispanic White, non-Hispanic Black or non-Hispanic Asian children to be diagnosed with acute lymphocytic leukemia (ALL) from 2009 to 2013...
March 1, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/27676583/effects-of-sweet-flavorings-and-nicotine-on-the-appeal-and-sensory-properties-of-e-cigarettes-among-young-adult-vapers-application-of-a-novel-methodology
#8
Nicholas I Goldenson, Matthew G Kirkpatrick, Jessica L Barrington-Trimis, Raina D Pang, Julia F McBeth, Mary Ann Pentz, Jonathan M Samet, Adam M Leventhal
INTRODUCTION: Product characteristics that impact e-cigarette appeal by altering the sensory experience of vaping need to be identified to formulate evidence-based regulatory policies. While products that contain sweet flavorings and produce a "throat hit" (i.e., desirable airway irritation putatively caused by nicotine) are anecdotally cited as desirable reasons for vaping among young adults, experimental evidence of their impact on user appeal is lacking. This experiment applied a novel laboratory protocol to assess whether: (1) sweet flavorings and nicotine affect e-cigarette appeal; (2) sweet flavorings increase perceived sweetness; (3) nicotine increases throat hit; and (4) perceived sweetness and throat hit are associated with appeal...
November 1, 2016: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/27635996/e-cigarettes-conventional-cigarettes-and-dual-use-in-korean-adolescents-and-university-students-prevalence-and-risk-factors
#9
Christina Jeon, Keum Ji Jung, Heejin Kimm, Sungkyu Lee, Jessica L Barrington-Trimis, Rob McConnell, Jonathan M Samet, Sun Ha Jee
OBJECTIVE: To examine risk factors associated with use of e-cigarettes only, conventional cigarettes only, and dual use in Korean adolescents and young adults. METHODS: In a cross-sectional study, anonymous questionnaires were completed between April-May, 2015 among 1) 2744 middle and high school students, aged 13-18, from Seoul, Incheon, Gyeonggi, and Cheongju, Korea and 2) 2167 university students, aged 19-29, from fourteen universities in Korea. RESULTS: The results show that 12...
November 1, 2016: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/27401102/e-cigarettes-cigarettes-and-the-prevalence-of-adolescent-tobacco-use
#10
Jessica L Barrington-Trimis, Robert Urman, Adam M Leventhal, W James Gauderman, Tess Boley Cruz, Tamika D Gilreath, Steve Howland, Jennifer B Unger, Kiros Berhane, Jonathan M Samet, Rob McConnell
BACKGROUND: Adolescent e-cigarette use has increased rapidly in recent years, but it is unclear whether e-cigarettes are merely substituting for cigarettes or whether e-cigarettes are being used by those who would not otherwise have smoked. To understand the role of e-cigarettes in overall tobacco product use, we examine prevalence rates from Southern California adolescents over 2 decades. METHODS: The Children's Health Study is a longitudinal study of cohorts reaching 12th grade in 1995, 1998, 2001, 2004, and 2014...
August 2016: Pediatrics
https://www.readbyqxmd.com/read/27296866/e-cigarettes-and-future-cigarette-use
#11
Jessica L Barrington-Trimis, Robert Urman, Kiros Berhane, Jennifer B Unger, Tess Boley Cruz, Mary Ann Pentz, Jonathan M Samet, Adam M Leventhal, Rob McConnell
BACKGROUND: There has been little research examining whether e-cigarette use increases the risk of cigarette initiation among adolescents in the transition to adulthood when the sale of cigarettes becomes legal. METHODS: The Children's Health Study is a prospectively followed cohort in Southern California. Data on e-cigarette use were collected in 11th and 12th grade (mean age = 17.4); follow-up data on tobacco product use were collected an average of 16 months later from never-smoking e-cigarette users at initial evaluation (n = 146) and from a sample of never-smoking, never e-cigarette users (n = 152) frequency matched to e-cigarette users on gender, ethnicity, and grade...
July 2016: Pediatrics
https://www.readbyqxmd.com/read/27161417/the-e-cigarette-social-environment-e-cigarette-use-and-susceptibility-to-cigarette-smoking
#12
Jessica L Barrington-Trimis, Kiros Berhane, Jennifer B Unger, Tess Boley Cruz, Robert Urman, Chih Ping Chou, Steve Howland, Kejia Wang, Mary Ann Pentz, Tamika D Gilreath, Jimi Huh, Adam M Leventhal, Jonathan M Samet, Rob McConnell
PURPOSE: One concern regarding the recent increase in adolescent e-cigarette use is the possibility that electronic (e-) cigarettes may be used by those who might not otherwise have used cigarettes, and that dual use, or transition to cigarette use alone, may follow. METHODS: Questionnaire data were obtained in 2014 from 11th/12th grade students attending schools in 12 communities included in the Southern California Children's Health Study. We evaluated the cross-sectional association between e-cigarette use, the social environment (family and friends' use and approval of e-cigarettes and cigarettes), and susceptibility to future cigarette use among never cigarette smokers (N = 1,694), using previously validated measures based on reported absence of a definitive commitment not to smoke...
July 2016: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/26688438/psychiatric-comorbidity-in-adolescent-electronic-and-conventional-cigarette-use
#13
Adam M Leventhal, David R Strong, Steve Sussman, Matthew G Kirkpatrick, Jennifer B Unger, Jessica L Barrington-Trimis, Janet Audrain-McGovern
The popularity of electronic (e-) cigarettes has greatly increased recently, particularly in adolescents. However, the extent of psychiatric comorbidity with adolescent e-cigarette use and dual use of conventional (combustible) and e-cigarettes is unknown. This study characterized psychiatric comorbidity in adolescent conventional and e-cigarette use. Ninth grade students attending high schools in Los Angeles, CA (M age = 14) completed self-report measures of conventional/e-cigarette use, emotional disorders, substance use/problems, and transdiagnostic psychiatric phenotypes consistent with the NIMH-Research Domain Criteria Initiative...
February 2016: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/26598059/patterns-of-alternative-tobacco-product-use-emergence-of-hookah-and-e-cigarettes-as-preferred-products-amongst-youth
#14
Tamika D Gilreath, Adam Leventhal, Jessica L Barrington-Trimis, Jennifer B Unger, Tess Boley Cruz, Kiros Berhane, Jimi Huh, Robert Urman, Kejia Wang, Steve Howland, Mary Ann Pentz, Chih Ping Chou, Rob McConnell
PURPOSE: There is a growing public health concern related to the rapid increase in the use of multiple tobacco products among adolescents. This study examined patterns of adolescent use of cigarettes, e-cigarettes, cigars/cigarillo, hookah/waterpipe, and smokeless/dip/chewing tobacco in a population of southern California adolescents. METHODS: Data from 2,097 11th- and 12th-grade participants in the Southern California Children's Health Study were collected via self-report in 2014...
February 2016: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/26216326/psychosocial-factors-associated-with-adolescent-electronic-cigarette-and-cigarette-use
#15
Jessica L Barrington-Trimis, Kiros Berhane, Jennifer B Unger, Tess Boley Cruz, Jimi Huh, Adam M Leventhal, Robert Urman, Kejia Wang, Steve Howland, Tamika D Gilreath, Chih-Ping Chou, Mary Ann Pentz, Rob McConnell
BACKGROUND: Use of electronic cigarettes (e-cigarettes) among adolescents has increased since their introduction into the US market in 2007. Little is known about the role of e-cigarette psychosocial factors on risk of e-cigarette or cigarette use in adolescence. METHODS: Information on e-cigarette and cigarette psychosocial factors (use and attitudes about use in the home and among friends) was collected from 11th- and 12th-grade participants in the Southern California Children's Health Study during the spring of 2014...
August 2015: Pediatrics
https://www.readbyqxmd.com/read/26214830/rotavirus-gastroenteritis-in-a-neonatal-unit-of-a-greek-tertiary-hospital-clinical-characteristics-and-genotypes
#16
Dimitra Koukou, Panagiota Chatzichristou, Georgios Trimis, Tania Siahanidou, Anna-Venetia Skiathitou, Emmanouil I Koutouzis, George A Syrogiannopoulos, Athanasia Lourida, Athanasios G Michos, Vassiliki P Syriopoulou
INTRODUCTION: Rotavirus (RV) infection in neonatal age can be mild or even asymptomatic. Several studies have reported that RV is responsible for 31%-87% of pediatric nosocomial diarrhea and causes gastroenteritis outbreaks in pediatric and neonatal units. OBJECTIVES: Study clinical characteristics, genotypes and risk factors of RV infection in neonatal age. METHODS: A prospective study was conducted from April 2009 till April 2013 in the neonatal special care unit of the largest tertiary pediatric hospital of Greece...
2015: PloS One
https://www.readbyqxmd.com/read/25383564/flavorings-in-electronic-cigarettes-an-unrecognized-respiratory-health-hazard
#17
Jessica L Barrington-Trimis, Jonathan M Samet, Rob McConnell
No abstract text is available yet for this article.
December 17, 2014: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/24260161/parental-smoking-and-risk-of-childhood-brain-tumors-by-functional-polymorphisms-in-polycyclic-aromatic-hydrocarbon-metabolism-genes
#18
MULTICENTER STUDY
Jessica L Barrington-Trimis, Susan Searles Nielsen, Susan Preston-Martin, W James Gauderman, Elizabeth A Holly, Federico M Farin, Beth A Mueller, Roberta McKean-Cowdin
BACKGROUND: A recent meta-analysis suggested an association between exposure to paternal smoking during pregnancy and childhood brain tumor risk, but no studies have evaluated whether this association differs by polymorphisms in genes that metabolize tobacco-smoke chemicals. METHODS: We assessed 9 functional polymorphisms in 6 genes that affect the metabolism of polycyclic aromatic hydrocarbons (PAH) to evaluate potential interactions with parental smoking during pregnancy in a population-based case-control study of childhood brain tumors...
2013: PloS One
https://www.readbyqxmd.com/read/23925828/trends-in-childhood-brain-tumor-incidence-1973-2009
#19
Roberta McKean-Cowdin, Pedram Razavi, Jessica Barrington-Trimis, Rachel Tobias Baldwin, Shahab Asgharzadeh, Myles Cockburn, Tarik Tihan, Susan Preston-Martin
In the mid-1980s, there was a rise in incidence rates of childhood brain tumors (CBT) in the United States that appeared to stabilize at a higher rate in the early 1990 s. An updated analysis of the pattern of CBT over the past 2 decades, with commentary on whether the elevated incidence rate has continued, is past due. We used Surveillance, Epidemiology and End Results (SEER) data to examine trends in incidence of CBT from 1973 through 2009. We examined age-adjusted incidence rates (AAIRs) and secular trends for all malignant brain tumors combined (SEER classification) by histologic tumor type and anatomic site...
November 2013: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/23486847/selection-of-p53-deficient-stromal-cells-in-the-tumor-microenvironment
#20
Elena Farmaki, Ioulia Chatzistamou, Panagiotis Bourlis, Eleni Santoukou, George Trimis, Athanasios G Papavassiliou, Hippokratis Kiaris
The tumor microenvironment is considered pro-oncogenic for reasons that, among others, involve the stimulation of cancer cell growth. However, little is known regarding how the tumor microenvironment affects the proliferation of stromal cells that coexist with cancer cells in the tumors. In the present study, we show that cancer cells trigger a paracrine response in normal fibroblasts that is not consistently mitogenic but may also become antimitogenic, inhibiting fibroblasts' proliferation in vitro. In vivo experiments on xenografts of MDA-MB-231 breast and A549 lung cancer cells in SCID mice or primary Notch-induced breast cancers that develop in transgenic mice showed that stromal cells frequently undergo senescence, confirming the presence of stress-inducing conditions within the tumor's microenvironment...
September 2012: Genes & Cancer
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