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seborrhic dermatitis

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https://www.readbyqxmd.com/read/28592369/preliminary-study-of-histamine-h4-receptor-expressed-on-human-cd4-t-cells-and-its-immunomodulatory-potency-in-the-il-17-pathway-of-psoriasis
#1
Song Hee Han, Min Seok Hur, Min Jung Kim, Bo Mi Kim, Kyoung Woon Kim, Hae Rim Kim, Yong Beom Choe, Kyu Joong Ahn, Yang Won Lee
BACKGROUND: Previous studies have shown the expression of histamine H4 receptor (H4R) on CD4(+) T cells, especially human CD4(+) Th2-polarized T cells. OBJECTIVE: This study aimed to investigate the role of H4R on these effector T cells in psoriasis. METHODS: We enrolled three patients each with active psoriasis, inactive psoriasis, scalp seborrheic dermatitis, and three normal controls, and compared the basal expression of H4R mRNA in their peripheral blood CD4(+) T cells...
May 29, 2017: Journal of Dermatological Science
https://www.readbyqxmd.com/read/28589618/comparison-of-different-regimens-of-pimecrolimus-1-cream-in-the-treatment-of-facial-seborrheic-dermatitis
#2
Juemin Zhao, Wenjia Sun, Chengfeng Zhang, Jiaqiang Wu, Yan Le, Chunyun Huang, Ye Liu, Leihong Xiang
BACKGROUND: Pimecrolimus 1% cream has already been proved to be an effective and safe alternative to treat seborrheic dermatitis. However, the treatment periods were inconstant in previous studies. OBJECTIVE: To evaluate the comparative efficacy of pimecrolimus 1% cream with different regimens for the treatment of facial seborrheic dermatitis. METHOD: Thirty patients with facial seborrheic dermatitis were enrolled and randomly distributed to three groups...
June 7, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28588486/potential-of-il-1-il-18-and-inflammasome-inhibition-for-the-treatment-of-inflammatory-skin-diseases
#3
REVIEW
Gabriele Fenini, Emmanuel Contassot, Lars E French
In 2002, intracellular protein complexes known as the inflammasomes were discovered and were shown to have a crucial role in the sensing of intracellular pathogen- and danger-associated molecular patterns (PAMPs and DAMPs). Activation of the inflammasomes results in the processing and subsequent secretion of the pro-inflammatory cytokines IL-1β and IL-18. Several autoinflammatory disorders such as cryopyrin-associated periodic syndromes and Familial Mediterranean Fever have been associated with mutations of genes encoding inflammasome components...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28566909/in-vitro-anti-malassezia-activity-of-castanea-crenata-shell-and-oil-soluble-glycyrrhiza-extracts
#4
Song Hee Han, Min Seok Hur, Min Jung Kim, Won Hee Jung, Minji Park, Jeong Hwan Kim, Hong Ju Shin, Yong Beom Choe, Kyu Joong Ahn, Yang Won Lee
BACKGROUND: A new shampoo with anti-Malassezia properties obtained from various plants is required to provide seborrheic dermatitis patients with a wider range of treatment options. OBJECTIVE: The aim of this study was to obtain in vitro susceptibility profiles of Malassezia restricta and M. globosa, the most important pathogenic organisms in the development of seborrheic dermatitis, to the plant extracts used in commercial anti-dandruff shampoos. METHODS: Minimal inhibitory concentrations (MICs) were determined for eight candidate plant extracts and two plant-derived natural products diluted with Leeming and Notman medium to final concentrations of 0...
June 2017: Annals of Dermatology
https://www.readbyqxmd.com/read/28560305/hydrocortisone-1-cream-and-sertaconazole-2-cream-to-treat-facial-seborrheic-dermatitis-a-double-blind-randomized-clinical-trial
#5
K Balighi, S Z Ghodsi, M Daneshpazhooh, S Ghale-Baghi, M Nasimi, A Azizpour
BACKGROUND: Seborrheic dermatitis (SD) is a chronic dermatitis with periods of remission and relapse that requires long-term treatment. OBJECTIVE: We compared the efficacy and safety of treatment with sertaconazole with standard corticosteroid medications in adults with facial SD. METHODS: In this double-blind, randomized controlled trial, 60 patients with a diagnosis of SD were enrolled. Patients were instructed to apply either sertaconazole 2% cream (30 patients) or hydrocortisone 1% cream (30 patients) twice daily to the affected area of the face...
June 2017: International Journal of Women's Dermatology
https://www.readbyqxmd.com/read/28541877/erythromelalgia-involving-the-face
#6
Rachel R Gilmore, Danielle S Applebaum, Jessica L Parsons, Sylvia Hsu
Erythromelalgia is a rare disorder characterized by burning pain, erythema, and increased temperature typically involving the distal extremities. Although it can progress to involve the face, erythromelalgia presenting only on the face is particularly rare. This disorder is often misdiagnosed when it presents on the extremities and is even more likely to be misdiagnosed when presenting only on the face, delaying appropriate treatment and causing considerable frustration for the patient. We report a case of a 26-year-old woman with erythromelalgia that involved only the face for a number of years and was treated unsuccessfully as rosacea, seborrheic dermatitis, and contact dermatitis...
April 15, 2017: Dermatology Online Journal
https://www.readbyqxmd.com/read/28537863/severe-pellagra-masked-by-concurrent-plaque-psoriasis-a-case-report-of-a-hidden-diagnosis
#7
Elizabeth A Wang, Jason Kao, Michelle Y Cheng, Chelsea Ma, Soneet Dhillon, Thomas Konia, Emanual Maverakis, Cindy J Chambers
Despite characteristic features, psoriasis can mimic other dermatologic conditions, such as seborrheic dermatitis, lichen simplex chronicus, and certain nutritional deficiencies such as pellagra. We present a patient with a longstanding history of severe plaque psoriasis who presented with disfiguring scaly plaques involving greater than 80% body surface area. The patient's disease was minimally responsive to multiple therapies. Repeat punch biopsies demonstrated parakeratosis, psoriasiform hyperplasia, and dilated blood vessels consistent with psoriasis...
May 15, 2017: Dermatology Online Journal
https://www.readbyqxmd.com/read/28504468/incubatory-environment-of-the-scalp-impacts-pre-emergent-hair-to-affect-post-emergent-hair-cuticle-integrity
#8
James R Schwartz, James P Henry, Kathy M Kerr, Michael J Flagler, Steve H Page, Nancy Redman-Furey
OBJECTIVES: To determine whether the oxidative stress transmitted to newly grown hair from an unhealthy scalp has physical consequences to the cuticular condition and function. METHODS: A uniquely designed 24-week clinical study included 8 weeks of pretreatment with a cosmetic shampoo and 16 weeks of treatment with either a potentiated zinc pyrithione (ZPT) antidandruff shampoo or a placebo cosmetic shampoo. This clinical design allowed the growth and acquisition of hair samples under conditions of varying but known scalp health as a result of treating a dandruff/seborrheic dermatitis (D/SD) population...
May 14, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28458770/treatment-of-seborrheic-dermatitis-using-a-novel-herbal-based-cream
#9
Deganit Barak-Shinar, Ruben Del Río, Lawrence J Green
Objective: Seborrheic dermatitis is a common relapsing inflammatory skin condition occurring in approximately 3 to 5 percent of the general population. Current available therapies control, but do not cure seborrhea. The study's objective was to determine the safety and efficacy of a barrier-based, nonsteroidal cream incorporating herbal extracts as a treatment for facial seborrheic dermatitis. Design: Interventional, open label, safety/efficacy study. Setting: At the baseline visit, the investigator selected a target area on the face...
April 2017: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/28453592/-cutaneous-myiasis-due-to-cochliomyia-hominivorax-associated-with-seborrheic-dermatitis
#10
Perla Calderón H, Camilo Rojas E, Werner Apt B, Douglas Castillo O
Myiasis is an infestation of tissues and organs of humans and animals by Diptera larvae (flies, horseflies, mosquitoes). They are located at different body sites, and classified clinically as cutaneous, visceral and cavitary. We report a 26-year-old woman with a history of seborrheic dermatitis and recent trip to Brazil. She presented with a seven days history of suppurating wounds in the parieto-occipital area of the scalp. At physical examination we found three ulcers of approximately 1.5 cm each, with multiple mobile larvae inside...
February 2017: Revista Médica de Chile
https://www.readbyqxmd.com/read/28400639/association-of-dermatoses-with-duration-and-quantum-of-alcohol-intake-a-comparative-cross-sectional-study
#11
Yugal Kishor Sharma, Pankaj Shukla, Roopa Nayak, Preeti Kothari, Aayush Gupta
BACKGROUND: Chronic alcohol intake impacts skin directly, through organ dysfunction or by modifying preexisting dermatoses. However, dermatoses afflicting chronic alcoholics figure in a few studies only. AIM: This study aims to correlate the spectrum of dermatoses in chronic alcoholics with the quantum/duration of alcohol intake and raised liver transaminases. MATERIALS AND METHODS: Adult males, totaling 196, ascertained to fulfill the Royal College of Psychiatry criteria for chronic alcoholism by the de-addiction center and referred for dermatological consult were enrolled as cases, and similar number of age-/sex-matched teetotallers, as controls...
March 2017: Indian Journal of Dermatology
https://www.readbyqxmd.com/read/28393697/targeting-malassezia-species-for-novel-synthetic-and-natural-antidandruff-agents
#12
Letizia Angiolella, Simone Carradori, Cristina Maccallini, Gustavo Giusiano, Claudiu T Supuran
Malassezia spp. are lipophilic yeasts not only present in the normal skin microflora, but also responsible of skin-related diseases (pityriasis versicolor, seborrheic/atopic dermatitis and dandruff) as well as systemic fungal infections in humans and animals. Their treatment and eradication are mainly based on old azole drugs, which are characterized by poor compliance, unpredictable clinical efficacy, emerging resistance and several side effects. These drawbacks have prompted the research toward novel synthetic and natural derivatives/nanomaterials targeting other pivotal enzymes/pathways such as carbonic anhydrase (MgCA) and lipases, alone or in combination, in order to improve the eradication rate of this fungus...
April 4, 2017: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/28392645/knowledge-and-behavior-regarding-cosmetics-in-koreans-visiting-dermatology-clinics
#13
Soyun Cho, Sohee Oh, Nack In Kim, Young Suck Ro, Joung Soo Kim, Young Min Park, Chun Wook Park, Weon Ju Lee, Dong Kun Kim, Dong Won Lee, Sang Jun Lee
BACKGROUND: Cosmetics can affect the skin condition profoundly, and yet no survey has been performed in Koreans visiting dermatology clinics. OBJECTIVE: To assess knowledge and consumer behavior regarding cosmetics in Koreans visiting dermatology clinics. METHODS: A questionnaire consisting of 43 questions concerning demographics and use/knowledge/selection/purchase of cosmetics was given to patients and accompanying persons who visited dermatologic clinics in university and private clinic settings...
April 2017: Annals of Dermatology
https://www.readbyqxmd.com/read/28383855/-how-i-explore%C3%A2-scalp-and-hairin-erythemato-squamous-disorders
#14
G E Piérard, C Piérard-Franchimont, T Hermanns-Lê
In their early stages, some dermatoses of the scalp such as psoriasis seborrheic dermatitis, tinea capitis and discoid lupus erythematosus are often hardly noticeable to others. However, the eruptions are occasionally severe and extensive. Reaching an adequate diagnosis is of utmost impor¬tance for an adequate healthcare.
October 2016: Revue Médicale de Liège
https://www.readbyqxmd.com/read/28332161/real-time-pcr-identification-of-six-malassezia-species
#15
Amin Ilahi, Inès Hadrich, Sourour Neji, Houaida Trabelsi, Fattouma Makni, Ali Ayadi
Lipophilic yeast Malassezia species is widely found on the skin surface of humans and other animals. This fungus can cause pityriasis versicolor, Malassezia folliculitis, and seborrheic dermatitis. Still now, there is a problem with species identification of Malassezia with conventional methods. We developed a real-time polymerase chain reaction (PCR) assay with multiple hybridization probes for detecting M. globosa, M. furfur, M. restricta, M. sympodialis, M. slooffiae, and M. pachydermatis. The amplification curves and specific melting peaks of the probes hybridized with real-time PCR product were used for species identifications...
June 2017: Current Microbiology
https://www.readbyqxmd.com/read/28331352/skin-disorders-in-parkinson-s-disease-potential-biomarkers-and-risk-factors
#16
REVIEW
Astrid-Helene Ravn, Jacob P Thyssen, Alexander Egeberg
Parkinson's disease (PD) is one of the most common neurodegenerative disorders, characterized by a symptom triad comprising resting tremor, rigidity, and akinesia. In addition, non-motor symptoms of PD are well recognized and often precede the overt motor manifestations. Cutaneous manifestations as markers of PD have long been discussed, and cumulative evidence shows an increased prevalence of certain dermatological disorders in PD. Seborrheic dermatitis is considered to occur as a premotor feature of PD referable to dysregulation of the autonomic nervous system...
2017: Clinical, Cosmetic and Investigational Dermatology
https://www.readbyqxmd.com/read/28329637/dermatological-screening-of-an-elderly-population-the-rotterdam-study
#17
Martijn G H Sanders, Joris A C Verkouteren, Luba M Pardo
BackgroundThe recent WHO burden of disease project showed that the non-fatal skin disease related burden is high, but also that prevalence rates of many common skin diseases are not well documented. The aim of this study is to give an overview of (untreated) skin diseases in a population based sample of elderly.MethodsIn 2010, a full body skin examination (FBSE) was embedded in the Rotterdam Study, a prospective population based cohort study of an elderly white-skinned population in the Netherlands. The examination was conducted by a dermatology-trained physician and focused on most common skin diseases (e...
September 15, 2016: Dermatology Online Journal
https://www.readbyqxmd.com/read/28290646/topical-medications-for-seborrheic-dermatitis
#18
Christopher Baumert, Megan Melo, E Chris Vincent
No abstract text is available yet for this article.
March 1, 2017: American Family Physician
https://www.readbyqxmd.com/read/28262107/rf-itraconazole-pulse-therapy-for-seborrheic-dermatitis-a-treatment-approach-to-consider
#19
V Fatsini-Blanch, M I Martínez-González, S Heras-González, A de Quintana-Sancho
No abstract text is available yet for this article.
March 2, 2017: Actas Dermo-sifiliográficas
https://www.readbyqxmd.com/read/28249066/global-skin-disease-morbidity-and-mortality-an-update-from-the-global-burden-of-disease-study-2013
#20
Chante Karimkhani, Robert P Dellavalle, Luc E Coffeng, Carsten Flohr, Roderick J Hay, Sinéad M Langan, Elaine O Nsoesie, Alize J Ferrari, Holly E Erskine, Jonathan I Silverberg, Theo Vos, Mohsen Naghavi
Importance: Disability secondary to skin conditions is substantial worldwide. The Global Burden of Disease Study 2013 includes estimates of global morbidity and mortality due to skin diseases. Objective: To measure the burden of skin diseases worldwide. Data Sources: For nonfatal estimates, data were found by literature search using PubMed and Google Scholar in English and Spanish for years 1980 through 2013 and by accessing administrative data on hospital inpatient and outpatient episodes...
May 1, 2017: JAMA Dermatology
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