keyword
https://read.qxmd.com/read/37629250/association-between-polymorphism-enos4-tpa-factor-v-leiden-prothrombin-and-methylenetetrahydrofolate-reductase-and-the-occurrence-of-legg-calv%C3%A3-perthes-disease
#21
JOURNAL ARTICLE
Anna Matuszewska, Oliwer Sygacz, Łukasz Matuszewski, Szymon Stec, Andrzej Grzegorzewski, Jacek Gągała
BACKGROUND: Legg-Calvé-Perthes (LCPD) disease is a complex condition affecting the femoral head's epiphysis in children. It occurs with a prevalence ranging from 0.4 to 29.0 cases per 100,000 children under the age of 15. It involves various factors, including genes associated with coagulation and fibrinolysis, pro-inflammatory factors, and vasoactive substances. METHODS: We investigated the relationship between genetic mutations associated with coagulation and vascular disorders and the occurrence of LCPD in Polish patients...
August 10, 2023: Journal of Clinical Medicine
https://read.qxmd.com/read/37622056/trends-in-the-use-of-total-hip-arthroplasty-in-the-pediatric-population-a-review-of-the-literature
#22
REVIEW
Correggio L Peagler, Alexander J Dobek, Sean Tabaie
Current literature shows that the utilization of total hip arthroplasty (THA) to address pediatric hip pathology has seen a significant rise worldwide in recent decades. However, performing THA in pediatric patients presents unique challenges due to their increased activity levels, varying skeletal maturity, and diverse medical conditions. These challenges have relegated THA to a secondary option for young patients. Nonetheless, despite these difficulties, recent studies have demonstrated a growing prevalence of THA in pediatrics...
August 2023: Curēus
https://read.qxmd.com/read/37600923/interleukin-6-receptor-blockade-improves-bone-healing-following-ischemic-osteonecrosis-in-adolescent-mice
#23
JOURNAL ARTICLE
Gen Kuroyanagi, Nobuhiro Kamiya, Ryosuke Yamaguchi, Harry K W Kim
OBJECTIVE: Juvenile ischemic osteonecrosis (JIO) of the femoral head is one of the most serious hip disorders causing a permanent deformity of the femoral head in childhood. We recently reported that interleukin 6 (IL-6) is significantly increased in the hip synovial fluid of patients with JIO and that articular chondrocytes are primary source of IL-6. Adolescent JIO is particularly challenging to treat and has poor outcome. This study determined if IL-6 receptor blockade prevents bone loss and improves the bone healing in adolescent JIO...
December 2023: Osteoarthritis and cartilage open
https://read.qxmd.com/read/37592869/recommendations-for-physiotherapy-and-physical-activity-for-children-with-legg-calv%C3%A3-perthes-disease-a-survey-of-pediatric-orthopedic-surgeons-and-physiotherapists-in-sweden
#24
JOURNAL ARTICLE
Louise Melin, Zlatica Rendek, Yasmin D Hailer
BACKGROUND AND PURPOSE: Physiotherapy, restrictions of physical activity, and weightbearing are part of the treatment of children with Legg-Calvé-Perthes disease (LCPD). Prescription practices are widely discussed and vary between pediatric orthopedic surgeons (POSs) and physiotherapists (PTs). The purpose of this study was to identify recommendations for treatment methods in clinical practice to find some consensus and elaborate guidelines. PATIENTS AND METHODS: A web-based questionnaire including 3 cases of LCPD (initial, fragmentation, and reossification stages) was answered by 25 POSs and 19 PTs...
August 16, 2023: Acta Orthopaedica
https://read.qxmd.com/read/37521400/long-term-survival-after-femoral-anterior-rotational-osteotomy-for-late-onset-legg-calv%C3%A3-perthes-disease-a-case-report-with-27-year-follow-up
#25
Akira Ikegami, Yoshinobu Oka, Shoichi Yamazoe, Kenji Takahashi
INTRODUCTION: The purpose of treatment for Legg-Calvé-Perthes disease (LCPD) is to regain the sphericity of the femoral head in childhood and prevent degenerative changes in adulthood. Due to the largely unsatisfactory results of conservative treatment for late-onset LCPD (i.e. patient age >9 years.), surgery is generally indicated. Various surgeries have been applied and the reported short-term results are generally good. However, few reports have described the long-term (approximately 30 years) outcomes of femoral anterior rotational osteotomy (ARO)...
July 2023: Journal of Orthopaedic Case Reports
https://read.qxmd.com/read/37519593/clinical-outcomes-of-open-wedge-varus-derotation-osteotomy-in-legg-calve-perthes-disease-among-6-12-year-old-children
#26
JOURNAL ARTICLE
Appuchip Gumin Tayeng, Aniruddha Sengupta, Priyajit Chaterjee
Background Legg-Calve-Perthes (LCP) disease during early childhood might lead to impaired blood circulation to the femoral head causing osteoarthritis and avascular necrosis of the femoral head. In most cases of children diagnosed after the age of nine years, the progression of LCP disease is associated with poor outcomes causing disability. This study aimed to evaluate the clinical and radiological outcomes of varus derotation osteotomy in children with LCD disease with a late presentation at 6-12 years of age...
June 2023: Curēus
https://read.qxmd.com/read/37498989/treatment-of-symptomatic-residual-deformity-in-legg-calv%C3%A3-perthes-disease-mid-term-outcomes-and-predictors-of-failure-after-surgical-hip-dislocation-with-femoral-head-reshaping-and-relative-neck-lengthening
#27
JOURNAL ARTICLE
Eduardo N Novais, Samantha L Ferraro, Pedro G Justo, Mariana G Ferrer, Patricia Miller, Young-Jo Kim, Michael B Millis
BACKGROUND: Treating patients with symptomatic hips after healed Legg-Calvé-Perthes disease (LCPD) is challenging, mainly because of the complexity of the deformity. We performed a retrospective study to evaluate clinical and radiographic outcomes, measure the survival rate, and identify predictors of failure following a surgical hip dislocation (SHD) with femoral-head reshaping and relative femoral-neck lengthening for the treatment of symptomatic residual hip deformity after healed LCPD...
October 4, 2023: Journal of Bone and Joint Surgery. American Volume
https://read.qxmd.com/read/37477108/femoral-head-reduction-osteotomy-for-the-treatment-of-late-sequela-of-legg-calv%C3%A3-perthes-disease-and-perthes-like-femoral-head-deformities
#28
JOURNAL ARTICLE
Hady H Eltayeby, Khaled Loutfy El-Adwar, Amin Abdelrazek Ahmed, Mena Micheal Mosa, Shawn C Standard
Femoral head reduction osteotomy (FHRO) was described to treat misshapen femoral head that is causing intraarticular hip pain. The published literature showed discrepancies in patient selection, surgical techniques, and decision to perform concurrent acetabular osteotomy. Very few studies used Standardized Outcome Measures (SOMs). This study aims to describe the technique of FHRO and report the results of our series of 22 patients using SOMs and compare them to former peer-reviewed articles. Twenty-two hips in 22 patients with hip pain caused by mishshapen femoral were treated with FHRO with or without triple pelvic osteotomy (TPO)...
July 19, 2023: Journal of Pediatric Orthopedics. Part B
https://read.qxmd.com/read/37458670/evaluating-the-effectiveness-of-interventions-targeting-only-the-acetabular-side-in-the-surgical-treatment-of-legg-calv%C3%A3-perthes-disease
#29
JOURNAL ARTICLE
M Albayrak, F Ugur
OBJECTIVE: This study aims to show the effectiveness of only acetabular-side surgeries for hips affected by Legg-Calvé-Perthes disease. PATIENTS AND METHODS: Twelve patients who underwent two different acetabular osteotomies -pembersal osteotomy and triple osteotomy - were evaluated retrospectively. Clinically, patients were examined for hip range of motion, flexion contracture, and hip extensor and abductor strength; the results were evaluated using the Harris hip score...
July 2023: European Review for Medical and Pharmacological Sciences
https://read.qxmd.com/read/37422572/-legg-calv%C3%A3-perthes-disease
#30
REVIEW
Alina Schwert
BACKGROUND: Legg-Calvé-Perthes disease (LCPD) is an important cause of limping and/or hip pain in preadolescent children. OBJECTIVE: Pathogenesis and epidemiology of LCPD, classification of disease stages, quantitative femoral head involvement and prognosis based on X‑ray images and magnetic resonance imaging (MRI). MATERIAL AND METHODS: Summary and discussion of the basic research and recommendations. RESULTS: Boys between 3 and 10 years of age are mostly affected...
October 2023: Radiologie (Heidelb)
https://read.qxmd.com/read/37415047/the-quality-of-online-information-on-legg-calv%C3%A3-perthes-disease-can-we-do-better
#31
JOURNAL ARTICLE
James A Nassur, Linsen T Samuel, Alexander J Acuña, Bridget Ellsworth, Atul F Kamath
INTRODUCTION: As patients increasingly utilize the Internet to obtain health-related information, the accuracy and usability of information prove critical, especially for patients and parents seeking care for relatively common orthopedic childhood disorders such as Legg-Calvé-Perthes (LCP) disease. Therefore, the purpose of this study is to evaluate available online health information regarding LCP disease. The study specifically seeks to (1) examine the accessibility, usability, reliability, and readability of online information, (2) compare the quality of sites from different sources, and (3) determine whether Health on the Net Foundation Code (HON-code) certification guarantees higher quality of information...
July 6, 2023: Archives of Orthopaedic and Trauma Surgery
https://read.qxmd.com/read/37391959/outcomes-of-varus-derotation-femoral-osteotomy-by-angle-blade-plate-in-legg-calve-perthes-disease-for-patient-above-eight-years-of-age-in-the-lateral-pillar-b-or-b-c-group
#32
JOURNAL ARTICLE
Q S Alam, M T Alam, P K Sutrodhar, M S Islam, M M Hossain, S I Salam, M K Saha, M M Rahman, M Z Hossain, M K Roy
Legg-Calve-Perthes disease (LCPD) that starts after 8 years (late onset) usually follow more aggressive course and the long-term outcome is also poor. Treatment method of LCPD that will produce best results is controversial particularly if the patients are with late-onset presentation. This prospective study was conducted from January 2015 to January 2019 at Dhaka Medical College Hospital and Health N Hope Hospital, Dhaka, Bangladesh. We evaluated the radiographic outcomes for patients who had varus derotation femoral osteotomy (VDRO)...
July 2023: Mymensingh Medical Journal: MMJ
https://read.qxmd.com/read/37306235/intraosseous-injection-of-mesenchymal-stem-cells-for-the-treatment-of-osteonecrosis-of-the-immature-femoral-head-and-prevention-of-head-deformity-a-study-in-a-pig-model
#33
JOURNAL ARTICLE
Sergio Martínez-Álvarez, María Galán-Olleros, Daniel Azorín-Cuadrillero, Ángel Palazón-Quevedo, África González-Murillo, Gustavo J Melen-Frajlich, Manuel Ramírez-Orellana, Tomás Epeldegui-Torre, Francisco Forriol
BACKGROUND: Cell therapy has been proposed as part of the therapeutic arsenal to assist bone formation and remodeling in the early stages of osteonecrosis of the femoral head. The purpose of this study is to determine the effects of intraosseous inoculation of mesenchymal stem cells on bone formation and remodeling in an established experimental model of osteonecrosis of the femoral head in immature pigs. METHODS: Thirty-one 4-week-old immature Yorkshire pigs were used...
2023: Science Progress
https://read.qxmd.com/read/37304198/mid-term-results-of-sub-trochanteric-valgus-osteotomy-for-symptomatic-late-stages-legg-calv%C3%A3-perthes-disease
#34
JOURNAL ARTICLE
Khaled M Emara, Ramy Ahmed Diab, Ahmed K Emara, Mohamed Eissa, Mostafa Gemeah, Shady Abdelghaffar Mahmoud
BACKGROUND: The treatment of late stages of Legg-Calvé-Perthes disease (LCPD) is controversial. Although the concept of femoral head containment is a well-established technique of treatment, its use remains debatable in the late stages of the disease, as it does not improve symptoms in terms of limb length discrepancy and gait. AIM: To assess the results of subtrochanteric valgus osteotomy in symptomatic patients with late-stage Perthes disease. METHODS: From 2000 to 2007, 36 symptomatic patients with late stage of Perthes disease were surgically treated with subtrochanteric valgus osteotomy and followed-up for 8 to 11 years using the IOWA score and range of motion (ROM) variables...
May 18, 2023: World Journal of Orthopedics
https://read.qxmd.com/read/37303366/legg-calv%C3%A3-perthes-disease-following-nephrotic-syndrome-with-long-term-steroid-use-in-a-three-year-old-boy-a-case-report
#35
Manami Ueshima, Atsushi Shimasaki, Tadateru Yasu
Nephrotic syndrome (NS) is one of the common pediatric diseases that require glucocorticoid treatment. Patients with NS might receive steroids for a long time if remission is not achieved. Evidence shows that long-term steroid use may induce osteoporosis in adults and children, and steroid use is well known to be related to avascular necrosis of the femoral head (ANFH) in adults. However, no pediatric case of AFNH caused by long-term steroid use due to NS has been reported. In this report, we describe the case of a three-year-old boy with a chief complaint of gait difficulty, who had been treated with glucocorticoid orally for a year because of NS...
May 2023: Curēus
https://read.qxmd.com/read/37288047/prognostic-value-of-bone-resorption-pattern-in-the-anterior-portion-of-the-femoral-head-in-legg-calv%C3%A3-perthes-disease
#36
JOURNAL ARTICLE
Kenichi Mishima, Yasunari Kamiya, Masaki Matsushita, Shiro Imagama
PURPOSE: To examine whether differences in bone resorption patterns in the anterior portion of the femoral head correlate with the prognosis of Legg-Calvé-Perthes disease. METHODS: Seventy-eight patients with unilateral Legg-Calvé-Perthes disease, who were diagnosed after 6.0 years of age, underwent the Salter innominate osteotomy from 1987 to 2013, and were followed up to skeletal maturity. The anterior bone resorption pattern of the femoral head was evaluated from a frog-leg lateral hip radiograph made in the middle of the fragmentation period, and classified into two types, an epiphysis-preserved type (P) and a physis-disrupted type (D)...
June 2023: Journal of Children's Orthopaedics
https://read.qxmd.com/read/37272199/morphometric-assessment-of-the-hip-joint-in-children-aged-2-13%C3%A2-years
#37
JOURNAL ARTICLE
Vildan Önal, Ayfer Metin Tellioğlu, Yasemin Durum Polat
Our study aimed to evaluate the hip joints of healthy children aged 2-13 years morphometrically through radiographic images. Demographic characteristics of 300 healthy children in our study include an average age of 6.4 years old based on the 2-to-13-year-old bracket and sex classified to 133 girls and 167 boys. A total of 600 normal hips from these children were digitally measured based on Acetabular Index, ACM angle, MZ distance, Sharp angle, CE angle, Femoral Head Coverage Ratio, Cranial, and medial joint space (MJS)...
June 4, 2023: Clinical Anatomy
https://read.qxmd.com/read/37266936/effects-of-bone-marrow-derived-mesenchymal-stem-cell-transplantation-in-piglet-legg-calve-perthes-disease-models-a-pilot-study
#38
JOURNAL ARTICLE
Yohei Tomaru, Hisashi Sugaya, Tomokazu Yoshioka, Norihito Arai, Tomoyuki Abe, Yuta Tsukagoshi, Hiroshi Kamada, Masashi Yamazaki, Hajime Mishima
This preliminary study investigated the efficacy and safety of bone marrow-derived mesenchymal stem cell transplantation in a piglet Legg-Calve-Perthes disease (LCPD) model. The LCPD model was induced in two Landrace piglets (6- and 7-week-old, weighing 12 and 17 kg, respectively) by ligaturing the femoral neck. In the first piglet, the natural LCPD course was observed. In the second piglet, 4 weeks after ligaturing the femoral neck, simple medium and medium containing 2.44 × 107 bone marrow-derived mesenchymal stem cells were transplanted into the right and left femoral heads after core decompression, respectively...
May 22, 2023: Journal of Pediatric Orthopedics. Part B
https://read.qxmd.com/read/37256481/pediatric-hip-arthroscopy-a-review-of-indications-and-treatment-outcomes
#39
REVIEW
Helen Crofts, Mark McConkey, Parth Lodhia
PURPOSE OF REVIEW: The use of hip arthroscopy has expanded substantially over the last decade, including in pediatric and adolescent populations. Indications for hip arthroscopy in the pediatric population continue to be refined and research of outcomes following hip arthroscopy has increased. The purpose of this review is to provide an overview of current indications for hip arthroscopy in the pediatric population and the outcomes for each indication. RECENT FINDINGS: Hip arthroscopy is used in the treatment of a range of pediatric hip conditions, spanning from the infant to young adult...
July 2023: Current Reviews in Musculoskeletal Medicine
https://read.qxmd.com/read/37248799/avascular-necrosis-of-the-femoral-head-in-a-cynomolgus-macaque-macaca-fascicularis
#40
Jeffrey S Frankel, Kristin L Gardiner, Angela K Brice, Lisa Hagan, Timothy J Manzi, Leah Makaron
A cynomolgus macaque presented with right hindlimb lameness as well as crepitus and decreased passive range of motion of the right coxal joint. Radiography and histopathology were consistent with avascular necrosis of the femoral head. This case is the first published report of this condition in a cynomolgus macaque.
May 29, 2023: Journal of Medical Primatology
keyword
keyword
5804
2
3
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.