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Implantable cardiac defibrillators

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https://www.readbyqxmd.com/read/29910581/physicians-knowledge-and-attitudes-in-saudi-arabia-regarding-implantable-cardiac-defibrillators
#1
Tariq Alhogbani, Fuad A Awwad, Abdullah S Aljasser
Objectives: To evaluate knowledge and attitude of physicians involved in the management of patients with heart failure regarding implantable cardioverter-defibrillator (ICD). Methods: We conducted personal interviews with physicians involved in treating patients with heart failure. Between October 2015 and February 2016, the study was conducted in hospitals in the Riyadh region where no cardiac electrophysiology service was available. Every participant was met in person and received an oral questionnaire that aimed to assess basic knowledge regarding ICD indications and benefits...
April 2018: Journal of the Saudi Heart Association
https://www.readbyqxmd.com/read/29907873/genetic-background-of-japanese-patients-with-pediatric-hypertrophic-and-restrictive-cardiomyopathy
#2
Takeharu Hayashi, Kousuke Tanimoto, Kayoko Hirayama-Yamada, Etsuko Tsuda, Mamoru Ayusawa, Shinichi Nunoda, Akira Hosaki, Akinori Kimura
Hypertrophic cardiomyopathy (HCM) and restrictive cardiomyopathy (RCM) present a high risk for sudden cardiac death in pediatric patients. The aim of this study was to identify disease-associated genetic variants in Japanese patients with pediatric HCM and RCM. We analyzed 67 cardiomyopathy-associated genes in 46 HCM and 7 RCM patients diagnosed before 16 years of age using a next-generation sequencing system. We found that 78% of HCM and 71% of RCM patients carried disease-associated genetic variants. Disease-associated genetic variants were identified in 80% of HCM patients with a family history and in 77% of HCM patients with no apparent family history (NFH)...
June 15, 2018: Journal of Human Genetics
https://www.readbyqxmd.com/read/29907652/cardiac-resynchronization-therapy-and-clinical-outcomes-in-continuous-flow-left-ventricular-assist-device-recipients
#3
Rakesh Gopinathannair, Henri Roukoz, Adarsh Bhan, Ashwin Ravichandran, Mustafa M Ahmed, Dmitry Familtsev, Geetha Bhat, Jennifer Cowger, Munazzah Abdullah, Chirag Sandesara, Rahul Dhawan, Emma J Birks, Jaimin R Trivedi, Mark S Slaughter
BACKGROUND: Many patients with heart failure continue cardiac resynchronization therapy (CRT) after continuous flow left ventricular assist device (CF-LVAD) implant. We report the first multicenter study to assess the impact of CRT on clinical outcomes in CF-LVAD patients. METHODS AND RESULTS: Analysis was performed on 488 patients (58±13 years, 81% male) with an implantable cardioverter defibrillator (ICD) (n=223) or CRT-D (n=265) who underwent CF-LVAD implantation at 5 centers from 2007 to 2015...
June 15, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29907466/sudden-death-risk-markers-for-patients-with-left-ventricular-ejection-fractions-greater-than-40
#4
REVIEW
Brian P Halliday, Amrit S Lota, Sanjay K Prasad
The major burden of sudden cardiac death (SCD) in patients with heart disease occurs in those with a left ventricular ejection fraction > 40%. Although the annual risk of SCD may be lower in these patients compared to those with lower LVEF, their lifetime cumulative risk of SCD may be greater due to a better overall prognosis. It is plausible that those with LVEF > 40% who are at highest risk of life-threatening arrhythmia will benefit from implantable cardioverter defibrillators. Features that identify patients with a LVEF > 40% at high risk of SCD are urgently needed...
June 12, 2018: Trends in Cardiovascular Medicine
https://www.readbyqxmd.com/read/29905788/extended-use-of-the-wearable-cardioverter-defibrillator-in-patients-at-risk-for-sudden-cardiac-death
#5
Valentina Kutyifa, Katherine Vermilye, Usama A Daimee, Scott McNitt, Helmut Klein, Arthur J Moss
Aims: Data on outcomes in patients using the wearable cardioverter-defibrillator (WCD) > 90 days are limited. We aimed to analyse the clinical course of patients with WCD use ≤90 days vs. WCD use >90 days. Methods and results: We assessed arrhythmia events during WCD use, and ejection fraction (EF) improvement/implantable cardioverter-defibrillator (ICD) implantation at the end of WCD use in patients with WCD use ≤90 days vs. WCD use >90 days enrolled in the WEARIT-II registry, further assessed by disease aetiology (ischaemic vs...
June 14, 2018: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29905629/local-vancomycin-effectively-reduces-surgical-site-infection-at-implant-site-in-rodents
#6
Jeffrey S Kroin, Jinyuan Li, Sasha Shafikhani, Kajal H Gupta, Mario Moric, Asokumar Buvanendran
BACKGROUND AND OBJECTIVES: Infected implantable devices represent a clinical challenge, because the customary option is to surgically remove the device, and that is associated with substantial cost and morbidity to the patient, along with patient dissatisfaction with the physician. Although prophylactic systemic antibiotics and sterile technique are the mainstay of prevention of surgical site infection (SSI) after implant, the incidence of SSI remains relatively high. Although some surgeons add local antibiotic at implant site during surgery, there is no scientific research to demonstrate if there is a benefit...
June 13, 2018: Regional Anesthesia and Pain Medicine
https://www.readbyqxmd.com/read/29904452/revisiting-the-role-of-antiarrhythmic-drugs-in-prevention-of-atrial-fibrillation-recurrence-a-single-center-retrospective-review
#7
Daniel An Mascarenhas, Munish Sharma
Background: We conducted a retrospective analysis to revisit the efficacy of four different commonly used antiarrhythmic drugs (AADs) in a single community hospital setting in the U.S. We used cardiac implantable electronic devices (CIEDs) to continuously monitor the patients for maintenance of sinus rhythm. The CIEDs in our study included insertable cardiac monitor (ICM), permanent pacemaker (PPM) and cardiac resynchronization therapy-defibrillator (CRT-D). The aim was to compare efficacy of commonly used AADs for maintenance of sinus rhythm in atrial fibrillation (AF) patients...
June 2018: Cardiology Research
https://www.readbyqxmd.com/read/29902218/assessment-of-the-clinical-efficacy-of-the-heart-spectrum-blood-pressure-monitor-for-diagnosis-of-atrial-fibrillation-an-unblinded-clinical-trial
#8
Wei-Fong Kao, Sen-Kuang Hou, Chun-Yao Huang, Chun-Chieh Chao, Chung-Chih Cheng, Yi-Jung Chen
Atrial fibrillation (AF) is the most common arrhythmia. The most common diagnostic method, 12-lead electrocardiogram (ECG), can record episodes of arrhythmia from which the type and severity can be determined. The Heart Spectrum Blood Pressure Monitor (P2; OSTAR Meditech Corp., New Taipei City, Taiwan) is used to measure cardiovascular pressure change with fast Fourier transform (FFT) analysis to obtain heart rate frequency variability and accurate blood pressure data. We compared the diagnostic efficacy of the Heart Spectrum Blood Pressure Monitor to a 12-lead ECG (gold standard) for patients with AF...
2018: PloS One
https://www.readbyqxmd.com/read/29899727/flecainide-induced-brugada-syndrome-in-a-patient-with-skeletal-muscle-sodium-channelopathy-a-case-report-with-critical-therapeutical-implications-and-review-of-the-literature
#9
Michele Cavalli, Barbara Fossati, Raffaele Vitale, Elisa Brigonzi, Vito A G Ricigliano, Lorenzo Saraceno, Rosanna Cardani, Carlo Pappone, Giovanni Meola
Skeletal muscle sodium channelopathies are a group of neuromuscular disorders associated with mutations in the SCN4A gene. Because principal sodium channel isoforms expressed in the skeletal muscles and the heart are distinct one from the other, this condition usually spares cardiac functioning. Nonetheless, evidence on a possible link between skeletal muscle and cardiac sodium channelopathies has emerged in recent years. To date, eight patients bearing pathogenetic mutations in the SCN4A gene and manifesting cardiac electrophysiological alterations have been reported in literature...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29897627/real-world-geographic-variations-in-the-use-of-cardiac-implantable-electronic-devices-the-panorama-2-observational-cohort-study
#10
Dirk Bastian, Iftikhar O Ebrahim, Ju-Yi Chen, Mien-Cheng Chen, Dejia Huang, Jin-Long Huang, Vadim A Kuznetsov, Bärbel Maus, Ajay M Naik, Koen J P Verhees, Ahmed R Al Fagih
BACKGROUND: Currently, several geographies around the world remain underrepresented in medical device trials. The PANORAMA 2 study was designed to assess contemporary region-specific differences in clinical practice patterns of patients with cardiac implantable electronic devices (CIEDs). METHODS: In this prospective, multicenter, observational, multi-national study, baseline and implant data of 4,706 patients receiving Medtronic CIEDs (either de novo device implants, replacements, or upgrades) were analyzed, consisting of: 54% implantable pulse generators (IPGs), 20...
June 13, 2018: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/29894362/video-assisted-thoracoscopic-monitoring-of-laser-lead-extraction-by-femoral-route
#11
Luca Bontempi, Francesca Vassanelli, Manuel Cerini, Lorenza Inama, Gianfranco Mitacchione, Daniele Giacopelli, Antonio Curnis
A 72-year-old man with a dual-chamber implantable defibrillator was referred to our center for transvenous lead extraction because of pocket infection and presence of an abandoned lead. We decided to proceed with a video-assisted thoracoscopic approach because of patient history and documented complete occlusion of the right subclavian vein. During the use of excimer laser for persistent adhesions, the ventricular lead broke down at the level of cavoatrial junction. To successfully remove the remaining portion of lead, we decided to use the excimer laser by femoral route...
June 11, 2018: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
https://www.readbyqxmd.com/read/29894017/arrhythmic-outcome-of-arrhythmogenic-right-ventricular-cardiomyopathy-patients-without-implantable-defibrillators
#12
Weijia Wang, Julia Cadrin Tourigny, Aditya Bhonsale, Crystal Tichnell, Brittney Murray, Oliver Monfredi, Jonathan Chrispin, Jane Crosson, Harikrishna Tandri, Cynthia A James, Hugh Calkins
BACKGROUND: Implantable defibrillators (ICD) are an important therapy for arrhythmogenic right ventricular cardiomyopathy (ARVC) patients at high risk of sudden death. Given the high appropriate ICD therapy rate, some have argued that the mere act of implanting an ICD inflates the malignant arrhythmia rate in ARVC. OBJECTIVE: To report the arrhythmic course of ARVC patients without ICDs at the fulfillment of the 2010 Task Force Criteria and explore predictors of malignant ventricular arrhythmias...
June 12, 2018: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/29893985/-management-of-hypertrophic-cardiomyopathy-the-most-common-inherited-heart-disease
#13
Peter Magnusson, Fredrik Gadler, Stellan Mörner
Hypertrophic cardiomyopathy is the most common cardiogenetic disease affecting 1/500-1/1 000 individuals. Dyspnea is common but chest pain, dizziness or fainting may also cause considerable limitation for the patient. The diagnosis can be suspected from ECG. Echocardiography confirms hypertrophy of at least 15 mm, usually in the septum. If the obstruction of the outflow tract is severe, myectomy or alcohol ablation can relieve symptoms. Genetic evaluation of family members is advisable. To reduce symptoms, betablockers are used; verapamil or disopyramide are alternatives...
June 11, 2018: Läkartidningen
https://www.readbyqxmd.com/read/29885825/long-term-single-center-experience-of-defibrillator-therapy-in-children-and-adolescents
#14
Gerrit Frommeyer, Sebastian Feder, Markus Bettin, Volker Debus, Julia Köbe, Florian Reinke, Anselm Uebing, Lars Eckardt, Hans Gerd Kehl
BACKGROUND: Implantable cardioverter-defibrillator (ICD) systems are established therapy for prevention of sudden cardiac death. Long-term data on ICD systems in children and adolescents is rare. The present study displays a long-term single-center follow-up of children and adolescents with ICD systems. METHODS AND RESULTS: The present study represents a single-center experience of patients younger than 18 years who received an ICD (n = 58). Follow-up data included in-house follow-up as well as examinations of collaborating specialists...
June 1, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29880624/unexpected-early-complication-of-implantable-cardioverter-defibrillator
#15
Ahmed Abdelhafez, Nancy Wassef, Kai Hogrefe, Mohsin Farooq
A 41-year-old woman was visiting Oxford, where she had a sudden cardiac arrest. Cardiopulmonary resuscitation was started by a bystander until the paramedics arrived, who found her in ventricular fibrillation, and delivered three shocks. After 28 min she had return of spontaneous circulation. Emergency coronary angiography revealed normal coronary arteries. Echocardiography followed by a cardiac MRI showed non-dilated left ventricles with no evidence of late gadolinium enhancement. She had a single-chamber implantable-cardioverter defibrillator (ICD)...
June 6, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29880299/outcomes-of-4838-patients-requiring-temporary-transvenous-cardiac-pacing-a-statewide-cohort-study
#16
Austin Chin Chwan Ng, Jerrett K Lau, Vincent Chow, Dona Adikari, David Brieger, Leonard Kritharides
BACKGROUND: Temporary-transvenous-cardiac-pacing (TTCP) is a potentially lifesaving procedure, however trends in its utilization and outcomes in unselected contemporary populations are all unknown. METHODS: Consecutive patients requiring TTCP between July-1, 2000 and December-31, 2013 were identified from a statewide registry of admitted patients. In addition, all patients who underwent other cardiac procedures including permanent-pacemaker (PPM) implantation, automated-implantable-cardiac-defibrillator (AICD) implantation, percutaneous-coronary-intervention (PCI), or coronary-artery-bypass-graft (CABG) surgery were identified for comparative outcome analyses...
May 31, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29878937/the-clinical-profile-of-a-non-selected-population-treated-with-sacubitril-valsartan-is-different-from-paradigm-hf-trial
#17
Lourdes Vicent, Alberto Esteban-Fernández, Manuel Gómez-Bueno, Javier De-Juan, Pablo Díez-Villanueva, Ángel Manuel Iniesta, Ana Ayesta, Hugo González-Saldívar, Antonio Rojas-González, Ramón Bover-Freire, Diego Iglesias, Marcos García-Aguado, Jesús A Perea-Egido, Manuel Martínez-Sellés
Our aim is to describe the characteristics of the patients receiving sacubitril/valsartan (SV) in daily clinical practice. This is a prospective registry in 10 hospitals including all patients who started SV in everyday clinical practice.From October 2016 to March 2017, 427 patients started treatment with SV. The mean age was 68.1±12.4 years and 30.5% were women (22.0% in PARADIGM-HF, p<0.001). Comparing our cohort with patients included in PARADIGM-HF, baseline treatment was different, with a lower ratio of angiotensin converting enzyme inhibitors/angiotensin II receptor blockers (2...
May 21, 2018: Journal of Cardiovascular Pharmacology
https://www.readbyqxmd.com/read/29878156/management-of-patients-with-ventricular-arrhythmias-and-prevention-of-sudden-cardiac-death-translating-guidelines-into-practice-results-of-the-european-heart-rhythm-association-survey
#18
Kristina H Haugaa, Gheorghe-Andrei Dan, Konstantinos Iliodromitis, Radoslaw Lenarczyk, Germanas Marinskis, Joaquin Osca, Daniel Scherr, Nikolaos Dagres
Prevention of sudden cardiac death (SCD) remains a partly unsolved task in cardiology. The European Society of Cardiology (ESC) guidelines on management of patients with ventricular arrhythmias and prevention of SCD published in 2015 considered the new insights of the natural history of diseases predisposing to SCD. The guidelines improved strategies for management of patients at risk of SCD and included both drug and device therapies. The intention of this survey was to evaluate the extent of the disparities between daily clinical practice and the 2015 SCD ESC guidelines among electrophysiology centres in Europe...
June 5, 2018: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29873873/change-of-sensing-vector-in-the-subcutaneous-icd-during-follow-up-and-after-device-replacement
#19
Markus Bettin, Benjamin Rath, Christian Ellermann, Patrick Leitz, Nils Bögeholz, Florian Reinke, Köbe Julia, Lars Eckardt, Gerrit Frommeyer
BACKGROUND: The subcutaneous implantable cardioverter defibrillator (S-ICD) has been established as a valuable alternative to transvenous ICD for prevention of sudden cardiac death. The system automatically chooses the optimal sensing vector. However, during follow-up and especially after device replacement we observed a change of the suggested sensing vector in automatic setup. Therefore, we analyzed frequency and reasons of vector change and its impact on inappropriate shocks (iAS)...
June 6, 2018: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/29871807/implantable-cardioverter-defibrillator-in-chagas-heart-disease-a-systematic-review-and-meta-analysis-of-observational-studies
#20
Andre A L Carmo, Marcos R de Sousa, Juan F Agudelo, Eric Boersma, Manoel O C Rocha, Antonio L P Ribeiro, Carlos A Morillo
BACKGROUND: In patients with Chagas cardiomyopathy (ChCM), sudden cardiac death (SCD) is the leading cause of mortality. Implantable cardioverter-defibrillator (ICD) is a well-established therapy for secondary prevention in patients with structural heart disease, but there are conflicting opinions regarding its efficacy and safety in patients with ChCM. The aim of this meta-analysis was to assess the efficacy of the ICD for secondary prevention in patients with ChCM, comparing mortality as the primary outcome of patients treated with ICD with those treated with amiodarone...
May 29, 2018: International Journal of Cardiology
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