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Müller's muscle

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https://www.readbyqxmd.com/read/29334540/predictors-of-success-following-muller-s-muscle-conjunctival-resection
#1
Joshua Dan, Kunal R Sinha, Daniel B Rootman
PURPOSE: This study aims to describe Muller's muscle-conjunctival resection surgery in terms of outcomes and potential factors that may predict final positions. METHODS: This cross-sectional cohort study included patients undergoing Muller's muscle-conjunctival resection surgery for involutional ptosis over a 15-year period. Success was defined in 2 ways: 1) final marginal reflex distance 1 (MRD1) ≥2.5 mm (MRD1 success) and 2) final difference in MRD1 ≤1 mm between eyelids (symmetry success)...
January 12, 2018: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/29333946/does-inside-passing-contribute-to-the-high-incidence-of-groin-injuries-in-soccer-a-biomechanical-analysis
#2
Thomas Dupré, Johannes Funken, Ralf Müller, Kristian R L Mortensen, Filip Gertz Lysdal, Markus Braun, Hartmut Krahl, Wolfgang Potthast
Groin injuries are common in soccer and often cause time-loss from training. While groin injuries have been linked to full effort kicking, the role of inside passing is unclear. Therefore, the purpose of this study was to investigate hip joint kinematics and muscle force, stress and contraction velocity for adductor longus and gracilis during inside passing. 3D kinematics of ten soccer players (23.4 yrs; 77.5 kg; 1.81 m) were captured with a motion capture system inside a Footbonaut. Muscle force and contraction velocity were determined with AnyBody Modelling System...
January 15, 2018: Journal of Sports Sciences
https://www.readbyqxmd.com/read/29320528/developmental-finite-element-analysis-of-cichlid-pharyngeal-jaws-quantifying-the-generation-of-a-key-innovation
#3
Tim Peterson, Gerd B Müller
Advances in imaging and modeling facilitate the calculation of biomechanical forces in biological specimens. These factors play a significant role during ontogenetic development of cichlid pharyngeal jaws, a key innovation responsible for one of the most prolific species diversifications in recent times. MicroCT imaging of radiopaque-stained vertebrate embryos were used to accurately capture the spatial relationships of the pharyngeal jaw apparatus in two cichlid species (Haplochromis elegans and Amatitlania nigrofasciata) for the purpose of creating a time series of developmental stages using finite element models, which can be used to assess the effects of biomechanical forces present in a system at multiple points of its ontogeny...
2018: PloS One
https://www.readbyqxmd.com/read/29316663/modulation-of-protein-quality-control-and-proteasome-to-autophagy-switch-in-immortalized-myoblasts-from-duchenne-muscular-dystrophy-patients
#4
Marion Wattin, Loïc Gaweda, Pascale Muller, Mathieu Baritaud, Charlotte Scholtes, Chloé Lozano, Kathrin Gieseler, Carole Kretz-Remy
The maintenance of proteome integrity is of primary importance in post-mitotic tissues such as muscle cells; thus, protein quality control mechanisms must be carefully regulated to ensure their optimal efficiency, a failure of these processes being associated with various muscular disorders. Duchenne muscular dystrophy (DMD) is one of the most common and severe forms of muscular dystrophies and is caused by mutations in the dystrophin gene. Protein quality control modulations have been diversely observed in degenerating muscles of patients suffering from DMD or in animal models of the disease...
January 7, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29246325/ap-1-oligodeoxynucleotides-reduce-aortic-elastolysis-in-a-murine-model-of-marfan-syndrome
#5
Rawa Arif, Marcin Zaradzki, Anca Remes, Philipp Seppelt, Reiner Kunze, Hannes Schröder, Simon Schwill, Stephan M Ensminger, Peter N Robinson, Matthias Karck, Oliver J Müller, Markus Hecker, Andreas H Wagner, Klaus Kallenbach
Marfan syndrome is characterized by high expression of matrix metalloproteinases (MMPs) in aortic smooth muscle cells (AoSMCs) associated with medial elastolysis and aortic root aneurysm. We aimed to reduce aortic elastolysis through decrease of MMP expression with decoy oligodeoxynucleotides (dODNs) neutralizing the transcription factor activating factor-1 (AP-1). AP-1 abundance in nuclear extracts as well as MMP-2 and MMP-9 expression were significantly increased in isolated mAoSMC of mgR/mgR Marfan mice compared to wild-type cells...
December 15, 2017: Molecular Therapy. Nucleic Acids
https://www.readbyqxmd.com/read/29225495/force-direction-patterns-promote-whole-body-stability-even-in-hip-flexed-walking-but-not-upper-body-stability-in-human-upright-walking
#6
Roy Müller, Christian Rode, Soran Aminiaghdam, Johanna Vielemeyer, Reinhard Blickhan
Directing the ground reaction forces to a focal point above the centre of mass of the whole body promotes whole body stability in human and animal gaits similar to a physical pendulum. Here we show that this is the case in human hip-flexed walking as well. For all upper body orientations (upright, 25°, 50°, maximum), the focal point was well above the centre of mass of the whole body, suggesting its general relevance for walking. Deviations of the forces' lines of action from the focal point increased with upper body inclination from 25 to 43 mm root mean square deviation (RMSD)...
November 2017: Proceedings. Mathematical, Physical, and Engineering Sciences
https://www.readbyqxmd.com/read/29210297/modern-morphological-methods-for-tadpole-studies-a-comparison-of-micro-ct-and-clearing-and-staining-protocols-modified-for-frog-larvae
#7
M Krings, H Müller, M J Heneka, D Rödder
Micro-computed tomography (micro-CT) scanning and three-dimensional reconstruction have revolutionized morphological studies. Whereas species descriptions and comparative studies formerly were based on external appearance and dissection, we now can visualize muscles, skeleton and viscera in intact animals. In most cases, visualization of internal structures depends on appropriate staining methods. Staining with iodine, phosphotungstic acid (PTA) and osmium tetroxide are established methods, but some problems remain...
December 6, 2017: Biotechnic & Histochemistry: Official Publication of the Biological Stain Commission
https://www.readbyqxmd.com/read/29207002/disability-fatigue-pain-and-their-associates-in-early-diffuse-cutaneous-systemic-sclerosis-the-european-scleroderma-observational-study
#8
Sébastien Peytrignet, Christopher P Denton, Mark Lunt, Roger Hesselstrand, Luc Mouthon, Alan Silman, Xiaoyan Pan, Edith Brown, László Czirják, Jörg H W Distler, Oliver Distler, Kim Fligelstone, William J Gregory, Rachel Ochiel, Madelon Vonk, Codrina Ancuta, Voon H Ong, Dominique Farge, Marie Hudson, Marco Matucci-Cerinic, Alexandra Balbir-Gurman, Øyvind Midtvedt, Alison C Jordan, Wendy Stevens, Pia Moinzadeh, Frances C Hall, Christian Agard, Marina E Anderson, Elisabeth Diot, Rajan Madhok, Mohammed Akil, Maya H Buch, Lorinda Chung, Nemanja Damjanov, Harsha Gunawardena, Peter Lanyon, Yasmeen Ahmad, Kuntal Chakravarty, Søren Jacobsen, Alexander J MacGregor, Neil McHugh, Ulf Müller-Ladner, Gabriela Riemekasten, Michael Becker, Janet Roddy, Patricia E Carreira, Anne Laure Fauchais, Eric Hachulla, Jennifer Hamilton, Murat Inanç, John S McLaren, Jacob M van Laar, Sanjay Pathare, Susanna Proudman, Anna Rudin, Joanne Sahhar, Brigitte Coppere, Christine Serratrice, Tom Sheeran, Douglas J Veale, Claire Grange, Georges-Selim Trad, Ariane L Herrick
Objectives: Our aim was to describe the burden of early dcSSc in terms of disability, fatigue and pain in the European Scleroderma Observational Study cohort, and to explore associated clinical features. Methods: Patients completed questionnaires at study entry, 12 and 24 months, including the HAQ disability index (HAQ-DI), the Cochin Hand Function Scale (CHFS), the Functional Assessment of Chronic Illness Therapy-fatigue and the Short Form 36 (SF36). Associates examined included the modified Rodnan skin score (mRSS), current digital ulcers and internal organ involvement...
November 30, 2017: Rheumatology
https://www.readbyqxmd.com/read/29204951/-real-life-efficacy-and-tolerability-of-methocarbamol-in-patients-suffering-from-refractory-muscle-related-low-back-pain-results-of-a-health-care-research-project-based-on-data-from-the-german-pain-practice-registry
#9
Michael A Überall, Oliver M D Emrich, Gerhard H H Müller-Schwefe
BACKGROUND: Subacute, muscle-related low/back pain (L/BP) is known to be difficult to treat and frequently requires more specific causal-oriented treatments with agents improving the increased muscle tone. Currently, only methocarbamol is approved and available for the 1st-line treatment of patients with muscle-related L/BP in Germany - however, without sufficient data on longer lasting effects (> 1 week) in elsewhere refractory patients. METHOD: Noninterventional cohort study, based on anonymized routine data of the German pain practice registry; retrospective evaluation of patients with refractory L/BP, who first time received a treatment with methocarbamol between October 1st until December 31st, 2015, and who documented their response to treatment with the standardized and validated instruments of the German pain questionnaire over at least 4 weeks (n = 251 patients)...
December 2017: MMW Fortschritte der Medizin
https://www.readbyqxmd.com/read/29204437/reference-values-of-flexion-and-supination-in-the-elbow-joint-of-a-cohort-without-shoulder-pathologies
#10
Mehmet F Güleçyüz, Matthias F Pietschmann, Stefan Michalski, Ferdinand M Eberhard, Alexander Crispin, Christian Schröder, Maximilian J Mittermüller, Peter E Müller
Background: After surgery of the long head of the biceps tendon, the examination of the biceps brachii muscle function and strength is common clinical practice. The muscle strength is usually compared with the uninjured contralateral side or with a matched pair group assuming that the uninjured side can be used as an appropriate reference. Hypothesis/Purpose: The purpose of this study was to define reference values of the supination and flexion strength in the elbow joint and to investigate the influence of the arm positions and various anthropometric factors...
2017: BioMed Research International
https://www.readbyqxmd.com/read/29198825/coupling-between-myogenesis-and-angiogenesis-during-skeletal-muscle-regeneration-is-stimulated-by-restorative-macrophages
#11
Claire Latroche, Michèle Weiss-Gayet, Laurent Muller, Cyril Gitiaux, Pascal Leblanc, Sophie Liot, Sabrina Ben-Larbi, Rana Abou-Khalil, Nicolas Verger, Paul Bardot, Mélanie Magnan, Fabrice Chrétien, Rémi Mounier, Stéphane Germain, Bénédicte Chazaud
In skeletal muscle, new functions for vessels have recently emerged beyond oxygen and nutrient supply, through the interactions that vascular cells establish with muscle stem cells. Here, we demonstrate in human and mouse that endothelial cells (ECs) and myogenic progenitor cells (MPCs) interacted together to couple myogenesis and angiogenesis in vitro and in vivo during skeletal muscle regeneration. Kinetics of gene expression of ECs and MPCs sorted at different time points of regeneration identified three effectors secreted by both ECs and MPCs...
December 12, 2017: Stem Cell Reports
https://www.readbyqxmd.com/read/29197953/prolonged-use-of-alendronate-alters-the-biology-of-cranial-repair-in-estrogen-deficient-rats-associated-simultaneous-immunohistochemical-expression-of-tgf-%C3%AE-1-%C3%AE-er-and-bmpr1b
#12
Allan Fernando Giovanini, Giuliene Nunes de Sousa Passoni, Isabella Göhringer, Tatiana Miranda Deliberador, João Cesar Zielak, Carmem Lucia Muller Storrer, Thais Andrade Costa-Casagrande, Rafaela Scariot
OBJECTIVES: TGF-β1 is a cytokine that may induce both osteoneogenesis through Runx-2 or fibrosis via the transcription of α-smooth muscle actin (α-SMA). Because it has been previously known that alendronate increases the level of TGF-β1 and that under the usual condition of bone metabolism the estrogen may prevent the fibrotic effect of TGF-β1, the aim of this study was to evaluate if alendronate alters the cellular differentiation process post calvarial surgery in estrogen-deficient specimens...
December 2, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29194523/modified-levator-muscle-resection-using-putterman-muller-s-muscle-conjunctival-resection-ptosis-clamp
#13
Ju-Wen Yang
Background: The traditional technique for levator muscle resection includes a time-consuming dissection procedure that causes tissue trauma and swelling. The Putterman ptosis clamp has been popularly used in recent years for conjunctival müllerectomy. In this paper, we describe a modified surgical technique for ptosis treatment using the Putterman ptosis clamp. The modified technique improves the surgical results of levator muscle resection. Objectives: We performed a retrospective case-series study to determine the outcomes and complications associated with the use of the Putterman ptosis clamp in levator muscle resection...
November 28, 2017: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/29194498/commentary-on-modified-levator-muscle-resection-using-putterman-m%C3%A3-ller-s-muscle-conjunctival-resection-ptosis-clamp
#14
Allen M Putterman
No abstract text is available yet for this article.
November 28, 2017: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/29177076/effectiveness-and-efficiency-of-different-weight-machine-based-strength-training-programmes-for-patients-with-hip-or-knee-osteoarthritis-a-protocol-for-a-quasi-experimental-controlled-study-in-the-context-of-health-services-research
#15
Inga Krauss, Gerhard Müller, Benjamin Steinhilber, Georg Haupt, Pia Janssen, Peter Martus
Introduction: Osteoarthritis is a chronic musculoskeletal disease with a major impact on the individual and the healthcare system. As there is no cure, therapy aims for symptom release and reduction of disease progression. Physical exercises have been defined as a core treatment for osteoarthritis. However, research questions related to dose response, sustainability of effects, economic efficiency and safety are still open and will be evaluated in this trial, investigating a progressive weight machine-based strength training...
2017: BMJ Open Sport & Exercise Medicine
https://www.readbyqxmd.com/read/29172004/early-onset-myopathies-clinical-findings-prevalence-of-subgroups-and-diagnostic-approach-in-a-single-neuromuscular-referral-center-in-germany
#16
K Vill, A Blaschek, D Gläser, M Kuhn, T Haack, B Alhaddad, M Wagner, R Kovacs-Nagy, M Tacke, L Gerstl, A S Schroeder, I Borggraefe, C Mueller, B Schlotter-Weigel, B Schoser, M C Walter, W Müller-Felber
BACKGROUND: Early-onset myopathies are a heterogeneous group of neuromuscular diseases with broad clinical, genetic and histopathological overlap. The diagnostic approach has considerably changed since high throughput genetic methods (next generation sequencing, NGS) became available. OBJECTIVE: We present diagnostic subgroups in a single neuromuscular referral center and describe an algorithm for the diagnostic work-up. METHODS: The diagnostic approach of 98 index patients was retrospectively analysed...
2017: Journal of Neuromuscular Diseases
https://www.readbyqxmd.com/read/29167204/reply-to-drs-henni-and-abraham-muscle-oxygen-content-at-exercise-in-patients-with-claudication
#17
J Carter Luck, Faisal Aziz, Lawrence I Sinoway, Matthew D Muller
No abstract text is available yet for this article.
November 1, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/29160568/nerve-detection-using-optical-spectroscopy-an-evaluation-in-four-different-models-in-human-and-swine-in-vivo-and-post-mortem
#18
Gerrit C Langhout, Torre M Bydlon, Marjolein van der Voort, Manfred Müller, Jeroen Kortsmit, Gerald Lucassen, Andrea J R Balthasar, Geert-Jan van Geffen, Thorsten Steinfeldt, Henricus J C M Sterenborg, Benno H W Hendriks, Theo J M Ruers
OBJECTIVE: Identification of peripheral nerve tissue is crucial in both surgery and regional anesthesia. Recently, optical tissue identification methods are presented to facilitate nerve identification in transcutaneous procedures and surgery. Optimization and validation of such techniques require large datasets. The use of alternative models to human in vivo, like human post mortem, or swine may be suitable to test, optimize and validate new optical techniques. However, differences in tissue characteristics and thus optical properties, like oxygen saturation and tissue perfusion are to be expected...
November 21, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/29126388/yrna-expression-predicts-survival-in-bladder-cancer-patients
#19
Yuri Tolkach, Anna Franziska Stahl, Eva-Maria Niehoff, Chenming Zhao, Glen Kristiansen, Stefan Cajetan Müller, Jörg Ellinger
BACKGROUND: Non-coding RNAs play an important role in human carcinogenesis. YRNAs (Ro-associated Y), a novel class of non-coding RNAs, have been identified as biomarker in various malignancies, but remain to be studied in urinary bladder cancer (BCA) patients. METHODS: The expression of all four YRNAs (RNY1, RNY3, RNY4, RNY5) was determined in archival BCA (urothelial carcinoma, n = 88) and normal urothelial bladder (n = 30) tissues using quantitative real-time PCR...
November 10, 2017: BMC Cancer
https://www.readbyqxmd.com/read/29109262/myoanatomy-of-the-velvet-worm-leg-revealed-by-laboratory-based-nanofocus-x-ray-source-tomography
#20
Mark Müller, Ivo de Sena Oliveira, Sebastian Allner, Simone Ferstl, Pidassa Bidola, Korbinian Mechlem, Andreas Fehringer, Lorenz Hehn, Martin Dierolf, Klaus Achterhold, Bernhard Gleich, Jörg U Hammel, Henry Jahn, Georg Mayer, Franz Pfeiffer
X-ray computed tomography (CT) is a powerful noninvasive technique for investigating the inner structure of objects and organisms. However, the resolution of laboratory CT systems is typically limited to the micrometer range. In this paper, we present a table-top nanoCT system in conjunction with standard processing tools that is able to routinely reach resolutions down to 100 nm without using X-ray optics. We demonstrate its potential for biological investigations by imaging a walking appendage of Euperipatoides rowelli, a representative of Onychophora-an invertebrate group pivotal for understanding animal evolution...
November 6, 2017: Proceedings of the National Academy of Sciences of the United States of America
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