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https://www.readbyqxmd.com/read/29456939/outcomes-of-bone-anchored-hearing-aid-implant-at-universiti-kebangsaan-malaysia-medical-centre-ukmmc
#1
Suhana Abdul Rahim, Bee-See Goh, Safinaz Zainor, Roslenda Abdul Rahman, Asma Abdullah
The cross sectional study was conducted in Universiti Kebangsaan Malaysia Medical Center (UKMMC), Malaysia from August 2012 to December 2013. All patients implanted with in UKMMC from December 2001 until December 2012 was included. Glasgow Benefit Inventory (GBI) questionnaires and UKMMC questionnaires were used as part of the assessment tool. The GBI is a scoring which measures the change in health status produced by surgical interventions. UKMMC questionnaires was invented by our department to assess questions related to social and life style of patients and also the cosmetic perspective Baha implant and other daily related activities...
March 2018: Indian Journal of Otolaryngology and Head and Neck Surgery
https://www.readbyqxmd.com/read/29455502/-case-control-study-on-the-effect-of-meniscus-shaping-on-knee-function-after-anterior-cruciate-ligament-reconstruction
#2
Li-Feng Fu, Jin-Tao Hu, Zheng Wang, Xin Chen
OBJECTIVE: To observe the effect of the meniscus shaping on the knee function and stability after anterior cruciate ligament reconstruction(ACLR). METHODS: A total of 64 ACLR patients were included from January 2013 to January 2015. The control group was the ACLR patients with intact meniscus, in which 24 males and 6 females. The mean age was(32.8±5.5) years old(ranged, 22 to 43 years old). The injury side was left on 17 cases and right on 13 cases. The mean follow-up time was(15...
August 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29455058/physical-activity-combined-with-resistance-training-reduces-symptoms-of-frailty-in-older-adults-a-randomized-controlled-trial
#3
Koutatsu Nagaia, Toshiaki Miyamato, Akio Okamae, Akira Tamaki, Hiroyuki Fujioka, Yosuke Wada, Yuki Uchiyama, Ken Shinmura, Kazuhisa Domen
INTRODUCTION: Increased physical activity (PA) is a crucial factor in the prevention of physical deterioration, and resistance training (RT) is also a common and effective intervention for older adults. However, the effects of PA as an adjunct to RT on frailty status remains unclear; therefore, we clarified the effect of a PA intervention with feedback, as an adjunct to resistance strength training, on the physical and mental outcomes of frail older adults. MATERIALS AND METHODS: We employed a randomized controlled trial...
February 13, 2018: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/29453914/medication-adherence-and-health-related-quality-of-life-among-patients-with-chronic-obstructive-pulmonary-disease
#4
Nejc Horvat, Igor Locatelli, Mitja Kos, Ana Janežič
This study evaluated medication adherence and health-related quality of life (HRQoL) of Slovenian patients with chronic obstructive pulmonary disease (COPD) and examined the factors associated with HRQoL. Demographic and therapy information was collected from 65 patients through interviews. The St. George's Respiratory Questionnaire and the Morisky Medication Adherence Scale were used to evaluate HRQoL and adherence, resp. A multiple linear regression model was used to assess the association between the factors and HRQoL...
March 1, 2018: Acta Pharmaceutica
https://www.readbyqxmd.com/read/29452599/feasibility-and-acceptability-of-pre-operative-physical-activity-to-improve-patient-outcomes-after-major-cancer-surgery-study-protocol-for-a-pilot-randomised-controlled-trial-pepa-trial
#5
Daniel Steffens, Jane Young, Paula R Beckenkamp, James Ratcliffe, Freya Rubie, Nabila Ansari, Neil Pillinger, Michael Solomon
BACKGROUND: There is a need for evidence of the effectiveness of pre-operative exercise for patients undergoing major cancer surgery; however, recruitment to such trials can be challenging. The PrE-operative Physical Activity (PEPA) Trial will establish the feasibility and acceptability of a pre-operative exercise programme aimed to improve patient outcomes after cytoreductive surgery and pelvic exenteration. The secondary aim is to obtain pilot data on the likely difference in key outcomes (post-operative complications, length of hospital stay, post-operative functional capacity and quality of life) to inform the sample size calculation for the substantive randomised clinical trial...
February 17, 2018: Trials
https://www.readbyqxmd.com/read/29451701/phase-1b-study-of-pasireotide-everolimus-and-selective-internal-radioembolization-therapy-for-unresectable-neuroendocrine-tumors-with-hepatic-metastases
#6
Hyun S Kim, Walid L Shaib, Chao Zhang, Ganji Purnachandra Nagaraju, Christina Wu, Olatunji B Alese, Zhengjia Chen, Edith Brutcher, Meredith Renfroe, Bassel F El-Rayes
BACKGROUND: Neuroendocrine tumors (NETs) metastasize to the liver. Everolimus and selective internal radioembolization (SIRT) are approved treatments. Pasireotide is a somatostatin analogue with an affinity for somatostatin receptors 1, 2, 3, and 5. Everolimus and pasireotide may potentiate SIRT radiosensitization and inhibit rebound angiogenesis. This study evaluated the safety of pasireotide, everolimus, and SIRT. METHODS: This 3 + 3 phase 1 trial evaluated 3 dose levels of everolimus (2...
February 16, 2018: Cancer
https://www.readbyqxmd.com/read/29450241/smartphone-addiction-daily-interruptions-and-self-reported-productivity
#7
Éilish Duke, Christian Montag
The advent of the smartphone has dramatically altered how we communicate, navigate, work and entertain ourselves. While the advantages of this new technology are clear, constant use may also bring negative consequences, such as a loss of productivity due to interruptions in work life. A link between smartphone overuse and loss of productivity has often been hypothesized, but empirical evidence on this question is scarce. The present study addressed this question by collecting self-report data from N = 262 participants, assessing private and work-related smartphone use, smartphone addiction and self-rated productivity...
December 2017: Addictive Behaviors Reports
https://www.readbyqxmd.com/read/29449496/patient-reported-outcomes-resource-use-and-social-participation-of-patients-with-rheumatoid-arthritis-treated-with-biologics-in-alberta-experience-of-indigenous-and-non-indigenous-patients
#8
Cheryl Barnabe, Louise Crane, Tyler White, Brenda Hemmelgarn, Gilaad G Kaplan, Liam Martin, Walter P Maksymowych
OBJECTIVE: To characterize patient-reported outcomes, resource use, and social participation during the course of biologic therapy for indigenous and non-indigenous patients with rheumatoid arthritis (RA). METHODS: Patients initiating biologic therapy (2004 to 2012) were characterized longitudinally for patient-reported outcomes including physical function measured by the Health Assessment Questionnaire, EQ-5D, well-being [Medical Outcomes Study Short Form-36 (SF-36)], and visual analog scales for pain, fatigue, sleep, stiffness, and patient's global assessment...
February 15, 2018: Journal of Rheumatology
https://www.readbyqxmd.com/read/29449201/peer-coaching-through-mhealth-targeting-physical-activity-in-people-with-parkinson-disease-feasibility-study
#9
Cristina Colón-Semenza, Nancy K Latham, Lisa M Quintiliani, Terry D Ellis
BACKGROUND: Long-term engagement in exercise and physical activity mitigates the progression of disability and increases quality of life in people with Parkinson disease (PD). Despite this, the vast majority of individuals with PD are sedentary. There is a critical need for a feasible, safe, acceptable, and effective method to assist those with PD to engage in active lifestyles. Peer coaching through mobile health (mHealth) may be a viable approach. OBJECTIVE: The purpose of this study was to develop a PD-specific peer coach training program and a remote peer-mentored walking program using mHealth technology with the goal of increasing physical activity in persons with PD...
February 15, 2018: JMIR MHealth and UHealth
https://www.readbyqxmd.com/read/29449200/mhealth-technology-and-nurse-health-coaching-to-improve-health-in-diabetes-protocol-for-a-randomized-controlled-trial
#10
Sheridan Miyamoto, Madan Dharmar, Sarina Fazio, Yajarayma Tang-Feldman, Heather M Young
BACKGROUND: Chronic diseases, including diabetes mellitus, are the leading cause of mortality and disability in the United States. Current solutions focus primarily on diagnosis and pharmacological treatment, yet there is increasing evidence that patient-centered models of care are more successful in improving and addressing chronic disease outcomes. OBJECTIVE: The objective of this clinical trial is to evaluate the impact of a mobile health (mHealth) enabled nurse health coaching intervention on self-efficacy among adults with type-2 diabetes mellitus...
February 15, 2018: JMIR Research Protocols
https://www.readbyqxmd.com/read/29447329/randomised-phase-iii-trial-of-vinflunine-plus-capecitabine-versus-capecitabine-alone-in-patients-with-advanced-breast-cancer-previously-treated-with-an-anthracycline-and-resistant-to-taxane
#11
M Martin, M Campone, I Bondarenko, D Sakaeva, S Krishnamurthy, L Roman, L Lebedeva, J-C Vedovato, M Aapro
Background: Capecitabine is an approved standard therapy for anthracycline- and taxane-pretreated locally advanced or metastatic breast cancer (BC). Vinflunine has demonstrated single-agent activity in phase II studies in this setting, and activity and tolerability when combined with capecitabine. We compared the combination of vinflunine plus capecitabine (VC) with single-agent capecitabine. Patients and methods: Patients with locally recurrent/metastatic BC previously treated or resistant to an anthracycline and resistant to taxane therapy were randomly assigned to either vinflunine (280 mg/m2, day 1) plus oral capecitabine (825 mg/m2 twice daily [bid], days 1-14) every 3 weeks (q3w) or single-agent oral capecitabine (1250 mg/m2 bid, days 1-14) q3w...
February 10, 2018: Annals of Oncology: Official Journal of the European Society for Medical Oncology
https://www.readbyqxmd.com/read/29446809/cost-of-common-low-back-pain-and-lumbar-radiculopathy-in-rheumatologic-consultation-in-lom%C3%A3
#12
Eyram Fianyo, Owonayo Oniankitan, C Tagbor Komi, Kodjo Kakpovi, Prénam Houzou, E S Koffi-Tessio Viwalé, Moustafa Mijiyawa
BACKGROUND: The cost of low back pain was the subject of few studies in black Africa. AIM: To assess the cost of common low back pain and lumbar radiculopathy in Lomé. METHODS: A six months study was realised in the rheumatologic department of CHU Sylvanus Olympio. 103 consecutive patients suffering from a common low back pain or lumbar radiculopathy were included. To assess direct, indirect and non-financial costs they were questioned about their expense during the year...
March 2017: La Tunisie Médicale
https://www.readbyqxmd.com/read/29445354/effects-of-acupuncture-on-the-recovery-outcomes-of-stroke-survivors-with-shoulder-pain-a-systematic-review
#13
Janita Pak Chun Chau, Suzanne Hoi Shan Lo, Xingfeng Yu, Kai Chow Choi, Alexander Yuk Lun Lau, Justin Che Yuen Wu, Vivian Wing Yan Lee, William Hoi Ngai Cheung, Jessica Yuet Ling Ching, David R Thompson
Background: Poststroke shoulder pain limits stroke survivors' physical functioning, impairs their ability to perform daily activities, and compromises their quality of life. The use of acupuncture to manage shoulder pain after a stroke is believed to free the blockage of energy flow and produce analgesic effects, but the evidence is unclear. We therefore conducted a systematic review to summarize the current evidence on the effects of acupuncture on the recovery outcomes of stroke survivors with shoulder pain...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29445306/repository-corticotropin-injection-in-patients-with-rheumatoid-arthritis-resistant-to-biologic-therapies
#14
Peter A Fischer, Ronald J Rapoport
Introduction: Although synthetic and biologic disease-modifying antirheumatic drugs are available, many patients with rheumatoid arthritis have a difficult-to-control disease and need other treatment options. Repository corticotropin injection (RCI) may alleviate symptoms and exacerbations in patients with refractory disease. Methods: Nine patients with refractory rheumatoid arthritis were included in this study. Patients were maintained on their baseline therapies with a minimum of 7...
2018: Open Access Rheumatology: Research and Reviews
https://www.readbyqxmd.com/read/29444973/eight-hours-adaptive-deep-brain-stimulation-in-patients-with-parkinson-disease
#15
Mattia Arlotti, Sara Marceglia, Guglielmo Foffani, Jens Volkmann, Andres M Lozano, Elena Moro, Filippo Cogiamanian, Marco Prenassi, Tommaso Bocci, Francesca Cortese, Paolo Rampini, Sergio Barbieri, Alberto Priori
OBJECTIVES: To assess the feasibility and clinical efficacy of local field potentials (LFPs)-based adaptive deep brain stimulation (aDBS) in patients with advanced Parkinson disease (PD) during daily activities in an open-label, nonblinded study. METHODS: We monitored neurophysiologic and clinical fluctuations during 2 perioperative experimental sessions lasting for up to 8 hours. On the first day, the patient took his/her daily medication, while on the second, he/she additionally underwent subthalamic nucleus aDBS driven by LFPs beta band power...
February 14, 2018: Neurology
https://www.readbyqxmd.com/read/29444740/associations-between-modifiable-lifestyle-factors-and-multidimensional-cognitive-health-among-community-dwelling-old-adults-stratified-by-educational-level
#16
Manqiong Yuan, Jia Chen, Yaofeng Han, Xingliang Wei, Zirong Ye, Liangwen Zhang, Y Alicia Hong, Ya Fang
BACKGROUND: Cognition is multidimensional, and each domain plays a unique and crucial part in successful daily life engagement. However, less attention has been paid to multi-domain cognitive health for the elderly, and the role of lifestyle factors in each domain remains unclear. METHODS: We conducted a cross-sectional study of 3,230 older adults aged 60+ years in Xiamen, China, in 2016. The Montreal Cognitive Assessment (MoCA) was used to measure general cognition and six specific sub-domains...
February 15, 2018: International Psychogeriatrics
https://www.readbyqxmd.com/read/29443744/serum-levels-of-vitamin-a-and-25-hydroxyvitamin-d3-25ohd3-as-reflectors-of-pulmonary-function-and-quality-of-life-qol-in-children-with-stable-asthma-a-case-control-study
#17
Ya-Jie Bai, Ru-Jun Dai
BACKGROUND: This study aims to explore the relationship between serum vitamin A and 25-hydroxyvitamin D3 (25OHD3) levels with pulmonary function and quality of life (QOL) in children with stable asthma. METHODS: A total of 117 cases of children with stable asthma were assigned into the case group and 129 healthy children underwent physical examination during the same period into the control group. Electrochemiluminescence was employed to determine serum vitamin A and 25OHD3 levels...
February 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29443458/the-functional-and-psychological-burden-of-empty-nose-syndrome
#18
Jamil Manji, Jayakar V Nayak, Andrew Thamboo
BACKGROUND: Empty nose syndrome (ENS) is a debilitating disorder thought to arise as a postsurgical phenomenon from excessive loss of nasal tissues. Affected patients often report a profound impact on all aspects of life, but the extent of this burden has not been quantified. We sought to determine the association of ENS with mental health and functional impairments. METHODS: A cross-sectional study was performed of individuals with ENS recruited from online ENS forums...
February 14, 2018: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/29441775/-hydrating-cleansing-efficacy-and-tolerability-of-new-formulations-with-hyaluronic-acid-0-2-for-intimate-hygiene-in-the-woman-in-fertile-age-and-menopause
#19
Francesca Albani, Adriana Bonfigli, Francesca Consolaro, Luigi Rigano, Monica Campisi
Dehydration of genital areas, known as vaginal dryness, frequently affects woman's life, from fertile to postmenopausal period, and must be treated with specific products, including proper intimate cleansing. Based on that, two new cleanser formulations, characterized by Hyaluronic Acid 0.2% as main ingredient, have been developed (Hyalo Gyn® Intimo Active and Hyalo Gyn® Intimo Advance), with the aim to provide an effective hydration of the vaginal, vulvar, perianal and anal areas beyond guaranteeing daily intimate hygiene...
April 2018: Minerva Ginecologica
https://www.readbyqxmd.com/read/29441579/brain-anatomy-of-the-4-day-old-european-rabbit
#20
Nanette Y Schneider, Frédérique Datiche, Gérard Coureaud
The European rabbit (Oryctolagus cuniculus) is a widely used model in fundamental, medical and veterinary neurosciences. Besides investigations in adults, rabbit pups are relevant to study perinatal neurodevelopment and early behaviour. To date, the rabbit is also the only species in which a pheromone - the mammary pheromone (MP) - emitted by lactating females and active on neonatal adaptation has been described. The MP is crucial since it contributes directly to nipple localisation and oral seizing in neonates, i...
February 14, 2018: Journal of Anatomy
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