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https://www.readbyqxmd.com/read/29222303/responsiveness-of-patient-reported-outcome-measurement-information-system-promis-pain-domains-and-disease-specific-patient-reported-outcome-measures-in-children-and-adults-with-sickle-cell-disease
#1
REVIEW
Susanna Curtis, Amanda M Brandow
Case 1: A 33-year-old man with hemoglobin SS (homozygous hemoglobin S) disease presents for his regular clinic visit. He had 6 hospital admissions for pain over the past year. He also has avascular necrosis of the right hip. He takes daily hydroxyurea with hematologic changes indicative of compliance. He also takes morphine sustained release twice daily and morphine immediate release every 6 hours as needed for pain. He feels that more optimal pain control at home would help him reduce his number of hospital admissions in the upcoming year and improve his daily functioning at home...
December 8, 2017: Hematology—the Education Program of the American Society of Hematology
https://www.readbyqxmd.com/read/29218820/frequency-of-going-outdoors-and-health-related-quality-of-life-among-older-adults-examining-the-moderating-role-of-living-alone-and-employment-status
#2
Kazuhiro Harada, Kouhei Masumoto, Keiko Katagiri, Ai Fukuzawa, Makoto Chogahara, Narihiko Kondo, Shuichi Okada
AIM: Going outdoors more frequently is beneficial for maintaining and improving health-related quality of life (HRQOL) among older adults. However, individual differences can alter the effects of going outdoors. The present study aimed to examine whether relationships between going outdoors and HRQOL were moderated by living alone and employment status. METHODS: The present study was a secondary analysis of 14-month prospective data (n = 613). Variables used in this study were baseline data on the frequency of going outdoors, HRQOL (physical and mental component summary scores assessed using the Japanese version of the Medical Outcomes study Short Form 8-Item Health Survey), living alone, employment status, potential confounders (sex, age, educational level and instrumental activities of daily living) and follow-up data on HRQOL...
December 7, 2017: Geriatrics & Gerontology International
https://www.readbyqxmd.com/read/29218068/prostheses-used-in-laparoscopic-inguinal-hernia-repair-biocompatibility-postoperative-complications-and-quality-of-life-review-of-the-literature
#3
Alexandra Florina Trandafir, Dorin Eugen Popa, Danut Vasile
INTRODUCTION: There is a continuous concern about meshes used in laparoscopic inguinal hernia repair, which mainly relates to their biocompatibility and ability to decrease postoperative complications and recurrence rate; in other words, efforts are made to find the "ideal" prosthesis. OBJECTIVES: To evaluate different prostheses used in laparoscopic inguinal hernia repair in terms of biocompatibility, postoperative complications, recurrence rate and quality of life, so that all the features could lead us to the "ideal" mesh...
September 2017: Mædica
https://www.readbyqxmd.com/read/29217467/why-should-we-measure-free-25-oh-vitamin-d
#4
REVIEW
Oleg Tsuprykov, Xin Chen, Carl-Friedrich Hocher, LianghongYin, Berthold Hocher
Vitamin D, either in its D2 or D3 form, is essential for normal human development during intrauterine life, kidney function and bone health. Vitamin D deficiency has also been linked to cancer development and some autoimmune diseases. Given this huge impact of vitamin D on human health, it is important for daily clinical practice and clinical research to have reliable tools to judge on the vitamin D status. The major circulating form of vitamin D3 is 25-hydroxyvitamin D3 (25(OH)D), although is not the most active metabolite, the concentrations of total 25-hydroxy vitamin D3 in the serum are currently routinely used in clinical practice to assess vitamin D status...
December 4, 2017: Journal of Steroid Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/29217090/walking-speed-differentially-alters-spinal-loads-in-persons-with-traumatic-lower-limb-amputation
#5
Brad D Hendershot, Iman Shojaei, Julian C Acasio, Christopher L Dearth, Babak Bazrgari
Persons with lower limb amputation (LLA) perceive altered motions of the trunk/pelvis during activities of daily living as contributing factors for low back pain. When walking (at a singular speed), larger trunk motions among persons with vs. without LLA are associated with larger spinal loads; however, modulating walking speed is necessary in daily life and thus understanding the influences of walking speed on spinal loads in persons with LLA is of particular interest here. Three-dimensional trunk-pelvic kinematics, collected during level-ground walking at self-selected (SSW) and two controlled speeds (∼1...
November 28, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/29216834/inventory-of-real-world-data-sources-in-parkinson-s-disease
#6
Audrey Tanguy, Linus Jönsson, Lianna Ishihara
BACKGROUND: Real world data have an important role to play in the evaluation of epidemiology and burden of disease; and in assisting health-care decision-makers, especially related to coverage and payment decisions. However, there is currently no overview of the existing longitudinal real world data sources in Parkinson's disease (PD) in the USA. Such an assessment can be very helpful, to support a future effort to harmonize real world data collection and use the available resources in an optimal way...
December 8, 2017: BMC Neurology
https://www.readbyqxmd.com/read/29216768/a-mysterious-case-of-complex-regional-pain-syndrome-in-a-9-year-old-girl
#7
Angela Burian, Othmar Schuhfried, Richard Crevenna
PURPOSE: To describe the clinical manifestation and the treatment of complex regional pain syndrome type II in childhood. METHODS: Using information on the symptoms, diagnosis, rehabilitation and outcome of a young patient with complex regional pain syndrome type II. RESULTS: A 9-year -old girl had severe pain in the region of the left foot, signs of a common fibular nerve entrapment, hyperalgesia not limited to the distribution of the injured nerve, weakness and temperature asymmetry unknown origin...
December 7, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/29214523/haematopoietic-stem-cell-transplantation-arrests-the-progression-of-neurodegenerative-disease-in-late-onset-tay-sachs-disease
#8
Karolina M Stepien, Su Han Lum, J Edmond Wraith, Christian J Hendriksz, Heather J Church, David Priestman, Frances M Platt, Simon Jones, Ana Jovanovic, Robert Wynn
Tay-Sachs disease is a rare metabolic disease caused by a deficiency of hexosaminidase A that leads to accumulation of GM2 gangliosides predominantly in neural tissue. Late-onset Tay-Sachs disease variant is associated with a higher level of residual HexA activity. Treatment options are limited, and there are a few described cases who have undergone haematopoietic stem cell transplantation (HSCT) with variable outcome.We describe a case of a 23-year-old male patient who presented with a long-standing tremor since 7 years of age...
December 7, 2017: JIMD Reports
https://www.readbyqxmd.com/read/29214150/the-physiocam-a-novel-non-contact-sensor-to-measure-heart-rate-variability-in-clinical-and-field-applications
#9
Maria I Davila, Gregory F Lewis, Stephen W Porges
Heart rate variability (HRV) is a reliable indicator of health status and a sensitive index of autonomic stress reactivity. Stress negatively affects physical and psychological wellness by decreasing cardiovascular health and reducing quality of life. Wearable sensors have made it possible to track HRV during daily activity, and recent advances in mobile technology have reduced the cost and difficulty of applying this powerful technique. Although advances have made sensors smaller and lighter, some burden on the subject remains...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/29213155/frailty-syndrome-and-socioeconomic-and-health-characteristics-among-older-adults
#10
Darlene Mara Dos Santos Tavares, Thais Aline de Freitas Corrêa, Flavia Aparecida Dias, Pollyana Cristina Dos Santos Ferreira, Maycon Sousa Pegorari
Objective: To investigate the association of frailty syndrome with socioeconomic and health variables among older adults. Methods: This is a cross-sectional, observational and analytical household research conducted with a sample of 1,609 urban elderly. We used: semi-structured questionnaire, scales (Katz, Lawton and shortened version of Geriatric Depression Scale) and Fragility Phenotype proposed by Fried. Descriptive analysis was performed along with a bivariate and multinomial logistic regression model (p <0...
September 30, 2017: Colombia Médica: CM
https://www.readbyqxmd.com/read/29212516/a-finite-element-model-of-the-lower-limb-during-stance-phase-of-gait-cycle-including-the-muscle-forces
#11
Arnaud Diffo Kaze, Stefan Maas, Pierre-Jean Arnoux, Claude Wolf, Dietrich Pape
BACKGROUND: Results of finite element (FE) analyses can give insight into musculoskeletal diseases if physiological boundary conditions, which include the muscle forces during specific activities of daily life, are considered in the FE modelling. So far, many simplifications of the boundary conditions are currently made. This study presents an approach for FE modelling of the lower limb for which muscle forces were included. METHODS: The stance phase of normal gait was simulated...
December 7, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/29212511/comparing-the-chinese-versions-of-two-knee-specific-questionnaires-ikdc-and-koos-reliability-validity-and-responsiveness
#12
Chien-Chih Huang, Wen-Shiang Chen, Mei-Wun Tsai, Wendy Tzyy-Jiuan Wang
BACKGROUND: The International Knee Documentation Committee Subjective Knee Form (IKDC) and the Knee Injury and Osteoarthritis Outcome Score (KOOS) are knee-specific questionnaires that have been widely used and translated into numerous languages. However, the differences in the psychometric properties between the Chinese IKDC and KOOS remain unclear. The purpose of this study was to conduct a cross-cultural adaptation of the Chinese IKDC and Chinese KOOS and to compare the psychometric properties of these two measures in patients with various knee injuries from the acute stage up to 12 weeks after receiving treatment...
December 6, 2017: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/29211233/elderly-caregivers-living-in-urban-rural-and-high-social-vulnerability-contexts
#13
Sofia Cristina Iost Pavarini, Anita Liberalesso Neri, Allan Gustavo Brígola, Ana Carolina Ottaviani, Érica Nestor Souza, Estefani Serafim Rossetti, Mariélli Terassi, Nathalia Alves de Oliveira, Bruna Moretti Luchesi
OBJECTIVE Comparing the differences in the sociodemographic, care and health profiles of elderly caregivers of the elderly living in urban, rural, and high social vulnerability contexts. METHOD A cross-sectional study developed with elderly caregivers enrolled in the Family Health Units of a municipality in the interior of São Paulo. Household interviews and evaluations were conducted on: Activities of Daily Living (ADL), self-reported pain, frailty, cognition, life satisfaction, family functionality, burden, stress and hope...
2017: Revista da Escola de Enfermagem da U S P
https://www.readbyqxmd.com/read/29211169/artisanal-fisherwomen-shellfish-gatherers-analyzing-the-impact-of-upper-limb-functioning-and-disability-on-health-related-quality-of-life
#14
Juliana Dos Santos Müller, Ila Rocha Falcão, Maria Carolina Barreto Moreira Couto, Wendel da Silva Viana, Ivone Batista Alves, Denise Nunes Viola, Courtney Georgette Woods, Rita de Cássia Franco Rêgo
The aim is to analyze upper limb functioning and disability, and its association with health-related quality of life among artisanal fisherwomen from Bahia, Brazil. Cross-sectional epidemiological study was conducted with a sample of 209 fisherwomen. Structured questionnaires were used for socio-demographic and comorbidity information, as well as the instruments Disabilities of the Arm, Shoulder and Hand (DASH) and Short-Form Healthy Survey (SF-36) respectively, to evaluate the upper limbs and health-related quality of life...
November 2017: Ciência & Saúde Coletiva
https://www.readbyqxmd.com/read/29210875/comparison-of-the-effects-of-benson-muscle-relaxation-and-nature-sounds-on-the-fatigue-in-patients-with-heart-failure-a-randomized-controlled-clinical-trial
#15
Leila Seifi, Tahereh Najafi Ghezeljeh, Hamid Haghani
This study was conducted with the aim of comparing the effects of Benson muscle relaxation and nature sounds on fatigue in patients with heart failure. Fatigue and exercise intolerance as prevalent symptoms experienced by patients with heart failure can cause the loss of independence in the activities of daily living. It can also damage self-care and increase dependence to others, which subsequently can reduce the quality of life. This randomized controlled clinical trial was conducted in an urban area of Iran in 2016...
January 2018: Holistic Nursing Practice
https://www.readbyqxmd.com/read/29209612/anxiety-and-depression-in-the-portuguese-older-adults-prevalence-and-associated-factors
#16
Rute Dinis de Sousa, Ana Maria Rodrigues, Maria João Gregório, Jaime Da Cunha Branco, Maria João Gouveia, Helena Canhão, Sara Simões Dias
Anxiety and depression in the elderly individuals have been studied around the world, and some authors consider them among the most serious problems faced by modern societies. With recent economic crisis-very important in Southern European countries-isolation, loneliness, and exclusion of the active society, mental problems are probably raising and associated with distinct factors. In this cross-sectional analysis, nested in a longitudinal population-based cohort study, we analyze anxiety and depression prevalence, and their related factors, in a representative cohort of Portuguese seniors...
2017: Frontiers in Medicine
https://www.readbyqxmd.com/read/29209200/smart-aging-platform-for-evaluating-cognitive-functions-in-aging-a-comparison-with-the-moca-in-a-normal-population
#17
Sara Bottiroli, Cristina Tassorelli, Marialisa Lamonica, Chiara Zucchella, Elena Cavallini, Sara Bernini, Elena Sinforiani, Stefania Pazzi, Paolo Cristiani, Tomaso Vecchi, Daniela Tost, Giorgio Sandrini
Background: Smart Aging is a Serious games (SGs) platform in a 3D virtual environment in which users perform a set of screening tests that address various cognitive skills. The tests are structured as 5 tasks of activities of daily life in a familiar environment. The main goal of the present study is to compare a cognitive evaluation made with Smart Aging with those of a classic standardized screening test, the Montreal Cognitive Assessment (MoCA). Methods: One thousand one-hundred thirty-one healthy adults aged between 50 and 80 (M = 64...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/29209162/characterization-of-cochlear-vestibular-and-cochlear-vestibular-electrically-evoked-compound-action-potentials-in-patients-with-a-vestibulo-cochlear-implant
#18
T A K Nguyen, Samuel Cavuscens, Maurizio Ranieri, Konrad Schwarz, Nils Guinand, Raymond van de Berg, Thomas van den Boogert, Floor Lucieer, Marc van Hoof, Jean-Philippe Guyot, Herman Kingma, Silvestro Micera, Angelica Perez Fornos
The peripheral vestibular system is critical for the execution of activities of daily life as it provides movement and orientation information to motor and sensory systems. Patients with bilateral vestibular hypofunction experience a significant decrease in quality of life and have currently no viable treatment option. Vestibular implants could eventually restore vestibular function. Most vestibular implant prototypes to date are modified cochlear implants to fast-track development. These use various objective measurements, such as the electrically evoked compound action potential (eCAP), to supplement behavioral information...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/29208008/-i-just-feel-comfortable-out-here-there-s-something-about-the-place-staff-and-client-perceptions-of-a-remote-australian-aboriginal-drug-and-alcohol-rehabilitation-service
#19
Alice Munro, Julaine Allan, Anthony Shakeshaft, Courtney Breen
BACKGROUND: The need for effective, culturally safe residential rehabilitation services for Aboriginal people is widely acknowledged, however the combination of treatment components that is optimally effective, is not well defined. Most existing Aboriginal residential rehabilitation research has focused on describing client characteristics, and largely ignored the impact of treatment and service factors, such as the nature and quality of therapeutic components and relationships with staff...
December 6, 2017: Substance Abuse Treatment, Prevention, and Policy
https://www.readbyqxmd.com/read/29207918/intake-of-green-plant-membrane-with-dietary-oil-suppresses-postprandial-hypertriglyceridemia-in-rats-via-promoting-excretion-of-bile-acids
#20
Hiroko Matsuda, Shinpei Ooi, Ryo Otokozawa, Kodai Kumazaki, Eri Udagawa, Masaya Asakura, Daisuke Suzuki, Takaaki Shirai
Green-plant membrane is a phytonutrient present in green leafy vegetables at high concentration. Postprandial increases in blood triglyceride levels result in insulin resistance and type 2 diabetes. Additionally, dietary life and eating order also affect postprandial hypertriglyceridemia. In this study, the effects of once-daily intake of green-plant membrane with dietary oil on postprandial hypertriglyceridemia were investigated in vitro and in vivo. In vitro, green-plant membrane bound hydrophobic bile acids but did not inhibit pancreatic lipase activity...
December 6, 2017: Bioscience, Biotechnology, and Biochemistry
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