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https://www.readbyqxmd.com/read/29676834/working-while-unwell-workplace-impairment-in-people-with-severe-asthma
#1
Sarah A Hiles, Erin S Harvey, Vanessa M McDonald, Matthew Peters, Philip Bardin, Paul N Reynolds, John W Upham, Melissa Baraket, Zaheerodin Bhikoo, Jeffrey Bowden, Ben Brockway, Li Ping Chung, Belinda Cochrane, Gloria Foxley, Jeffrey Garrett, Mark Hew, Lata Jayaram, Christine Jenkins, Constance Katelaris, Gregory Katsoulotos, Mariko S Koh, Vicky Kritikos, Marina Lambert, David Langton, Alexis Lara Rivero, Guy B Marks, Peter G Middleton, Aldoph Nanguzgambo, Naghmeh Radhakrishna, Helen Reddel, Janet Rimmer, Anne Marie Southcott, Michael Sutherland, Francis Thien, Peter Ab Wark, Ian A Yang, Elaine Yap, Peter G Gibson
BACKGROUND: Severe asthma affects quality of life; however, its impact on workplace productivity is poorly understood. OBJECTIVE: To compare workplace productivity - absenteeism and presenteeism - and impairment in daily activities in severe and non-severe asthma over time and identify characteristics associated with presenteeism in severe asthma. METHODS: The Severe Asthma Web-based Database (SAWD) is an ongoing observational registry from Australia, New Zealand and Singapore...
April 20, 2018: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29674287/self-perceived-gait-stability-modulates-the-effect-of-daily-life-gait-quality-on-prospective-falls-in-older-adults
#2
R H A Weijer, M J M Hoozemans, J H van Dieën, M Pijnappels
BACKGROUND: Quality of gait during daily life activities and perceived gait stability are both independent risk factors for future falls in older adults. RESEARCH QUESTION: We investigated whether perceived gait stability modulates the association between gait quality and falling in older adults. METHODS: In this prospective cohort study, we used one-week daily-life trunk acceleration data of 272 adults over 65 years of age. Sample entropy (SE) of the 3D acceleration signals was calculated to quantify daily life gait quality...
April 4, 2018: Gait & Posture
https://www.readbyqxmd.com/read/29674010/one-step-intraoperative-radiotherapy-optimizes-conservative-treatment-of-breast-cancer-with-advantages-in-quality-of-life-and-work-resumption
#3
Luca Sorrentino, Susanna Fissi, Ilaria Meaglia, Daniela Bossi, Ottavia Caserini, Serena Mazzucchelli, Marta Truffi, Sara Albasini, Paola Tabarelli, Marco Liotta, Giovanni B Ivaldi, Fabio Corsi
BACKGROUND: Intraoperative radiotherapy (IORT) could be not-inferior to external beam radiotherapy (EBRT) in selected patients, but toxicities, self-perception of body image, quality of life, and resumption of work or daily activities have been poorly explored. The aim of the present study was to compare these outcomes between EBRT, IORT full-dose (IORT-f) and IORT boost (IORT-b). METHODS: 443 consecutive patients, candidates for breast-conserving surgery, were included: EBRT was performed in 220 patients (49...
April 16, 2018: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/29673717/novel-fatty-acid-chain-modified-glp-1-derivatives-with-prolonged-in-vivo-glucose-lowering-ability-and-balanced-glucoregulatory-activity
#4
Xingguang Cai, Lidan Sun, Yuxuan Dai, Yosefa Avraham, Chunxia Liu, Jing Han, Yuan Liu, Dazhi Feng, Wenlong Huang, Hai Qian
Glucagon-like peptide-1 is a potent hypoglycemic hormone with beneficial properties for the treatment of diabetes. However, its half-life is short because the rapid metabolic degradation. This study aims to prolong the half-life of glucagon-like peptide-1 through conjugation with the fatty acid side chain which helps the conjugates to interact with the albumin. Firstly, we chose two optimized polypeptide chains which have tremendous hypoglycemic effect named Cys17 -Gly8 -GLP-1(7-36)-NH2 and Cys37 -Gly8 -GLP-1(7-37)-NH2 , and various fatty acid chains were modified...
April 11, 2018: Bioorganic & Medicinal Chemistry
https://www.readbyqxmd.com/read/29673340/active-commuting-to-and-from-university-obesity-and-metabolic-syndrome-among-colombian-university-students
#5
Antonio García-Hermoso, Andrea P Quintero, Enrique Hernández, Jorge Enrique Correa-Bautista, Mikel Izquierdo, Alejandra Tordecilla-Sanders, Daniel Prieto-Benavides, Carolina Sandoval-Cuellar, Katherine González-Ruíz, Emilio Villa-González, Robinson Ramírez-Vélez
BACKGROUND: There is limited evidence concerning how active commuting (AC) is associated with health benefits in young. The aim of the study was to analyze the relationship between AC to and from campus (walking) and obesity and metabolic syndrome (MetS) in a sample of Colombian university students. METHODS: A total of 784 university students (78.6% women, mean age = 20.1 ± 2.6 years old) participated in the study. The exposure variable was categorized into AC (active walker to campus) and non-AC (non/infrequent active walker to campus: car, motorcycle, or bus) to and from the university on a typical day...
April 19, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29673165/a-novel-detection-model-and-its-optimal-features-to-classify-falls-from-low-and-high-acceleration-activities-of-daily-life-using-an-insole-sensor-system
#6
Benjamin Cates, Taeyong Sim, Hyun Mu Heo, Bori Kim, Hyunggun Kim, Joung Hwan Mun
In order to overcome the current limitations in current threshold-based and machine learning-based fall detectors, an insole system and novel fall classification model were created. Because high-acceleration activities have a high risk for falls, and because of the potential damage that is associated with falls during high-acceleration activities, four low-acceleration activities, four high-acceleration activities, and eight types of high-acceleration falls were performed by twenty young male subjects. Encompassing a total of 800 falls and 320 min of activities of daily life (ADLs), the created Support Vector Machine model’s Leave-One-Out cross-validation provides a fall detection sensitivity (0...
April 17, 2018: Sensors
https://www.readbyqxmd.com/read/29672074/reciprocal-associations-between-positive-emotions-and-motivation-in-daily-life-network-analyses-in-anhedonic-individuals-and-healthy-controls
#7
Eeske van Roekel, Vera E Heininga, Charlotte Vrijen, Evelien Snippe, Albertine J Oldehinkel
Anhedonia reflects a dysfunction in the reward system, which can be manifested in an inability to enjoy pleasurable situations (i.e., lack of positive emotions), but also by a lack of motivation to engage in pleasurable activities (i.e., lack of motivation). Little is known about the interrelations between positive emotions and motivation in daily life, and whether these associations are altered in anhedonic individuals. In the present study, we used a network approach to explore the reciprocal, lagged associations between positive emotions and motivation in anhedonic individuals (N = 66) and controls (N = 68)...
April 19, 2018: Emotion
https://www.readbyqxmd.com/read/29670756/correlates-and-predictors-of-obesity-specific-quality-of-life-of-former-participants-of-a-residential-intensive-lifestyle-intervention
#8
A-M Elbe, P Elsborg, S Dandanell, J W Helge
Introduction: The aim of this study was to investigate the relationship between weight loss during and after a unique type of weight loss intervention, namely, a residential intensive lifestyle intervention (ILI), and participants' obesity-specific health-related quality of life (HRQOL) several years after the intervention. In the residential ILI under investigation, participants attended a 10- to 12-week long course away from their daily living environment, namely, at Ubberup Folk High School located in Denmark...
April 2018: Obesity Science & Practice
https://www.readbyqxmd.com/read/29670565/the-efficacy-of-psychological-interventions-for-managing-fatigue-in-people-with-multiple-sclerosis-a-systematic-review-and-meta-analysis
#9
Aung Zaw Zaw Phyo, Thibaut Demaneuf, Alysha M De Livera, George A Jelinek, Chelsea R Brown, Claudia H Marck, Sandra L Neate, Keryn L Taylor, Taylor Mills, Emily O'Kearney, Amalia Karahalios, Tracey J Weiland
Background: Multiple sclerosis (MS) is a complex, demyelinating disease of the central nervous system. Fatigue is commonly reported by people with MS (PwMS). MS-related fatigue severely affects daily activities, employment, socioeconomic status, and quality of life. Objective: We conducted this systematic review and meta-analysis to determine whether psychological interventions are effective in managing fatigue in PwMS. Data sources: We performed systematic searches of Medline, EMBASE, PsycINFO, and CINAHL to identify relevant articles published from database inception to April 5, 2017...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29670476/the-effect-of-tai-chi-exercise-on-the-risk-and-fear-of-falling-in-older-adults-a-randomized-clinical-trial
#10
Hamed Mortazavi, Mahbubeh Tabatabaeichehr, Ali Golestani, Mohammad Reza Armat, Mohammad Reza Yousefi
Background: Falling and fear of falling are among the most common problems of the elderly, which can cause illness, isolation, dependency and reduced quality of life in elderly. Exercise is recommended to prevent falling injuries in the elderly. Aim: This study aimed to examine the effect of Tai Chi exercise on the risk and fear of falling in older adults. Materials and Methods: In this randomized clinical trial, a total of 60 male and female elderly were randomly divided into two groups: Tai Chi exercise and control (daily activities) groups...
March 2018: Materia Socio-medica
https://www.readbyqxmd.com/read/29669095/choosing-solitude-age-differences-in-situational-and-affective-correlates-of-solitude-seeking-in-midlife-and-older-adulthood
#11
Jennifer C Lay, Theresa Pauly, Peter Graf, Atiya Mahmood, Christiane A Hoppmann
Objectives: Despite a basic need for social connection, individuals across the adult lifespan sometimes seek solitude - a phenomenon that is not well understood. This study examined the situational and affective correlates of solitude-seeking and how they may differ between middle-aged and older adults. Method: 100 community-dwelling adults aged 50-85 years (64% female, 56% East Asian, 36% European, 8% other) completed approximately 30 electronic daily life assessments over 10 days regarding their current location, affect, activities, and current and desired social context...
April 16, 2018: Journals of Gerontology. Series B, Psychological Sciences and Social Sciences
https://www.readbyqxmd.com/read/29668813/factors-influencing-the-impact-of-oral-health-on-the-daily-activities-of-adolescents-adults-and-older-adults
#12
Jaqueline Vilela Bulgareli, Eduardo Tanajura de Faria, Karine Laura Cortellazzi, Luciane Miranda Guerra, Marcelo de Castro Meneghim, Glaucia Maria Bovi Ambrosano, Antonio Carlos Frias, Antonio Carlos Pereira
OBJECTIVE: Analyze if clinical, sociodemographic and access to dental services variables influence the impact of oral health on the daily activities of adolescents, adults and older adults. METHODS: A cross-sectional study with secondary data from the State Oral Health Survey (SB São Paulo 2015) conducted in 163 cities of São Paulo. A total of 17,560 individuals from three age groups: 15-19-year-old (n = 5,558), 35-44-year-old (n = 6,051), and older people of 65 years or more (n = 5,951) participated in the survey...
2018: Revista de Saúde Pública
https://www.readbyqxmd.com/read/29668791/spirituality-in-palliative-care-experiences-of-an-interdisciplinary-team
#13
Isabel Cristina de Oliveira Arrieira, Maira Buss Thofehrn, Adrize Rutz Porto, Pedro Márlon Martter Moura, Caroline Lemos Martins, Michelle Barboza Jacondino
Objective To understand the experience of spirituality in the daily routine of a palliative care interdisciplinary team. Method A qualitative study was conducted with an oncological palliative care team in southern Brazil. The data was collected through phenomenological interviews in 2014, and interpreted using a hermeneutic phenomenological approach. Results Six professionals participated in the study. Spiritually-related activities, such as prayer and providing comprehensive care, were useful therapeutic resources for offering comfort, survival with dignity and humanization of death, in addition to helping the team and patients understand the end-of-life process and search for meaning in the suffering caused by illness...
2018: Revista da Escola de Enfermagem da U S P
https://www.readbyqxmd.com/read/29668375/evaluation-of-pelvis-postural-systems-in-spinal-cord-injury-patients-outcome-research
#14
Serena Dattoli, Mariele Colucci, Maria Grazia Soave, Rita De Santis, Leandro Segaletti, Claudia Corsi, Marco Tofani, Donatella Valente, Giovanni Galeoto
OBJECTIVES: Compare three commercially available postural systems to determine the best for treatment of patients suffering from spinal cord injury lesion below the cervical spine. DESIGN: Outcome Research. SETTING: Ambulatory. PARTICIPANTS: Thirteen patients were recruited for this study between March 2016 and July 2016 from the Occupational Therapy clinic of "Policlinico Umberto I" hospital in Rome and Occupational Therapy of "CPO" hospital in Ostia...
April 18, 2018: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/29667464/end-user-evaluation-of-a-kneeling-wheelchair-with-on-the-fly-adjustable-seating-functions
#15
Johanne Mattie, Angie Wong, Danny Leland, Jaimie Borisoff
A "kneeling" ultralight wheelchair prototype has been developed that allows users to adjust seat position "on the fly" for different activities throughout the day. The wheelchair includes independent adjustment functions for rear seat height, front seat height ("kneeling") and backrest angle.  Aim: This work aimed to gather feedback about the wheelchair's functionality and performance through end user evaluation trials.  Methods: Eight manual wheelchair users evaluated the prototype Kneeling Wheelchair for a range of activities...
April 18, 2018: Disability and Rehabilitation. Assistive Technology
https://www.readbyqxmd.com/read/29667314/the-diary-of-a-nonagenarian-centenarian-woman-with-dementia-memory-loss-life-changes-and-community-care-in-japan
#16
Sayuri Suwa, Saori Otani, Mayuko Tsujimura, Kotoko Nogawa, Yoko Shiya
AIM: This study aimed to explore the experiences and thoughts of a nonagenarian-centenarian woman with dementia living alone, through detailed analysis of her unsolicited diary. DATA SOURCE: After receiving consent from Aki (a pseudonym), her family and caregivers, copies of her diaries, hand-written in Japanese, were provided for analysis. METHODS: The content of the diaries was broadly organized into themes and qualitative content analysis carried out for each theme along a sequential timeline...
April 2018: International Journal of Nursing Practice
https://www.readbyqxmd.com/read/29667152/falls-in-mexican-older-adults-aged-60-years-and-older
#17
Luis M Valderrama-Hinds, Soham Al Snih, Nai-Wei Chen, Martin A Rodriguez, Rebeca Wong
BACKGROUND: Falls are a major cause of disability, morbidity, institutionalization, and mortality in older adults. OBJECTIVES: The purpose of the study was to examine the risk factors for falls among Mexican older adults aged 60 years and older. METHODS: This study included 6247 participants and their spouse or partner aged 60 years and older from the Mexican Health and Aging Study, an ongoing longitudinal study (2001-2012) conducted in Mexico...
April 17, 2018: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/29666126/domains-of-health-related-quality-of-life-in-age-related-macular-degeneration-a-qualitative-study-in-the-chinese-cultural-context
#18
Wei Bian, Junli Wan, Graeme Smith, Shiying Li, Mingqiong Tan, Fengjiao Zhou
OBJECTIVE: To explore which areas of health-related quality of life were affected in Chinese patients, and to identify whether the areas are well covered by validated questionnaires. DESIGN: A qualitative study based on semistructured interviews was conducted. A qualitative thematic analysis following the approach of Colaizzi was used to analyse the interview data for significant statements and phrases. The themes and subthemes organised from the analysis were then compared by using the following current instruments: National Eye Institute Visual Function Questionnaire (NEI-VFQ-25), Macular Disease Quality of life Questionnaire (MacDQoL) and Low-Luminance Questionnaire (LLD)...
April 17, 2018: BMJ Open
https://www.readbyqxmd.com/read/29665842/sensory-re-learning-of-the-upper-limb-after-stroke-sensupp-study-protocol-for-a-pilot-randomized-controlled-trial
#19
Håkan Carlsson, Birgitta Rosén, Hélène Pessah-Rasmussen, Anders Björkman, Christina Brogårdh
BACKGROUND: Many stroke survivors suffer from sensory impairments of their affected upper limb (UL). Although such impairments can affect the ability to use the UL in everyday activities, very little attention is paid to sensory impairments in stroke rehabilitation. The purpose of this trial is to investigate if sensory re-learning in combination with task-specific training may prove to be more effective than task-specific training alone to improve sensory function of the hand, dexterity, the ability to use the hand in daily activities, perceived participation, and life satisfaction...
April 17, 2018: Trials
https://www.readbyqxmd.com/read/29665583/clinical-effectiveness-and-potential-survival-benefit-of-us-guided-high-intensity-focused-ultrasound-therapy-in-patients-with-advanced-stage-pancreatic-cancer
#20
Milka Marinova, Hannah C Huxold, Jana Henseler, Martin Mücke, Rupert Conrad, Roman Rolke, Hojjat Ahmadzadehfar, Maximilian Rauch, Rolf Fimmers, Guido Luechters, Henning Cuhls, Lukas Radbruch, Hans H Schild, Holger Strunk
PURPOSE:  Pancreatic cancer (PaC) is a life-limiting tumor with a wide range of incapacitating symptoms such as cancer pain in more than 80 % of patients. This prospective interventional study addresses the clinical effectiveness of ultrasound-guided high-intensity focused ultrasound (HIFU) treatment for patients with advanced-stage PaC, including pain perception, tumor size and survival benefit. MATERIALS AND METHODS:  50 patients with late-stage PaC underwent HIFU...
April 17, 2018: Ultraschall in der Medizin
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