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Impact on patient outcomes

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https://www.readbyqxmd.com/read/29356463/spatial-barriers-impact-upon-appropriate-delivery-of-radiotherapy-in-breast-cancer-patients
#1
Fabrizio Stracci, Fortunato Bianconi, Chiara Lupi, Manuela Margaritelli, Alessio Gili, Cynthia Aristei
Radiotherapy (RT) is the standard treatment for breast cancer patients after conserving surgery or mastectomy when patients are at high risk of relapse. Major obstacles to appropriate RT delivery are journey times. Since studies on access to RT were carried out mostly in large countries, this study investigated factors in an Italian region and the influence of RT delivery on survival. A total of 4735 female candidates for RT were included in the study. A geographic information system calculated journey times from patients' homes and surgery hospitals to RT centers...
January 22, 2018: Cancer Medicine
https://www.readbyqxmd.com/read/29356438/impact-of-tobacco-alcohol-and-cannabis-use-on-treatment-outcomes-among-patients-experiencing-first-episode-psychosis-data-from-the-national-raise-etp-study
#2
Oladunni Oluwoye, Maria Monroe-DeVita, Ekaterina Burduli, Lydia Chwastiak, Sterling McPherson, Jon M McClellan, Michael G McDonell
AIM: The primary aim of this study was to examine the effect of recent tobacco, alcohol and cannabis use on treatment outcomes among participants experiencing first episode psychosis (FEP). METHODS: Secondary data analyses were conducted on 404 participants enrolled in the Recovery After an Initial Schizophrenia Episode-Early Treatment Program (RAISE-ETP) study. RAISE-ETP investigated the effectiveness of a coordinated specialty care (CSC) intervention for FEP in community mental health agencies in the United States...
January 22, 2018: Early Intervention in Psychiatry
https://www.readbyqxmd.com/read/29356436/health-insurance-and-use-of-recommended-routine-care-in-adults-with-cystic-fibrosis
#3
Susan S Li, Don Hayes, Joseph D Tobias, Wayne J Morgan, Dmitry Tumin
BACKGROUND: Low socioeconomic status is correlated with worse outcomes in patients with cystic fibrosis. Whether insurance status impacts adherence to care in this population is unknown. METHODS: Patients ≥18 years old in the CF Foundation Patient Registry (2005-2013) were grouped based on reported annual insurance as private, public (Medicaid, Medicare, or state medical assistance program), other, or no insurance. Random effects logistic regression evaluated association between change in insurance status and annual use of recommended routine care...
January 22, 2018: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29356359/impact-of-body-mass-index-on-the-oncological-outcomes-of-patients-with-upper-and-lower-urinary-tract-cancers-treated-with-radical-surgery-a-multi-institutional-retrospective-study
#4
Yasukiyo Murakami, Kazumasa Matsumoto, Masaomi Ikeda, Takuji Utsunomiya, Takahiro Hirayama, Dai Koguchi, Daisuke Matsuda, Norihiko Okuno, Yoshinori Taoka, Akira Irie, Masatsugu Iwamura
AIM: To evaluate the impact of body mass index (BMI) on the oncological outcomes of urothelial carcinoma (UC) patients. PATIENTS AND METHODS: We retrospectively analyzed data from 818 patients with upper tract urothelial cancer (UTUC) and bladder cancer (BC) who were treated with radical nephroureterectomy (RNU) or radical cystectomy (RC) between 1990 and 2015 at six different institutions in Japan. Patients with distant metastasis at diagnosis and those who received neoadjuvant therapies were excluded, leaving 727 eligible patients (UTUC: n = 441; BC: n = 286)...
January 22, 2018: Asia-Pacific Journal of Clinical Oncology
https://www.readbyqxmd.com/read/29356317/the-use-of-vascular-homografts-in-pediatric-small-bowel-transplantation-single-center-experience-over-a-decade
#5
Yong K Kwon, Nathaly Llore, Stuart S Kaufman, Cal S Matsumoto, Thomas M Fishbein, Raffaele Girlanda
Intestinal transplantation in children has evolved with more isolated small intestine transplants being performed compared to combined liver-intestine transplants. Consequently, surgical techniques have changed, frequently requiring the use of vascular homografts of small caliber to revascularize the isolated small intestine, the impact of which on outcomes is unknown. Among 106 pediatric intestine and multivisceral transplants performed at our center since 2003, 33 recipients of an isolated small intestine graft were included in this study...
January 22, 2018: Pediatric Transplantation
https://www.readbyqxmd.com/read/29356187/evaluation-of-margins-in-head-and-neck-squamous-cell-carcinoma-from-the-surgeon-s-perspective
#6
Philipp Baumeister, Konstantin Baumüller, Ulrich Harréus, Maximilian Reiter, Christian Welz
BACKGROUND: The surgeon's evaluation of resection status based on frozen section analysis during operation and pathological examination of resected specimens often differ. For this study, we recapitulated the surgeon's perspective during an operation, accordingly classified the evaluation of margins by the surgeon, and analyzed its impact on the outcome compared with the pathological results. METHODS: This was a retrospective analysis. As data sources, paper-based and digital patient files, as well as the Munich Cancer Registry database were used...
January 22, 2018: Head & Neck
https://www.readbyqxmd.com/read/29356080/striving-to-meet-targets-for-ideal-treatment-of-acute-myocardial-infarction-in-brazil-data-from-the-midwest-region
#7
Gustavo Carvalho, Salvador Rassi, Enio Guérios, Fernando A M Curado, Ana Tereza Bastos
OBJECTIVES: To evaluate the systematic chain of care for patients with acute ST-elevation myocardial infarction (STEMI) referred for primary angioplasty in a capital city in Midwestern Brazil. BACKGROUND: Acute myocardial infarction is recognized as an important cause of morbidity and mortality and as a public health problem worldwide. Early specialized care is crucial for a good prognosis. METHODS: All STEMI patients receiving care through the public health system at two tertiary care centers from March 2012 to June 2014 were retrospectively analyzed...
January 21, 2018: Journal of Interventional Cardiology
https://www.readbyqxmd.com/read/29356074/diabetes-technology-improving-care-improving-patient-reported-outcomes-and-preventing-complications-in-young-people-with-type-1-diabetes
#8
P Prahalad, M Tanenbaum, K Hood, D M Maahs
With the evolution of diabetes technology, those living with Type 1 diabetes are given a wider arsenal of tools with which to achieve glycaemic control and improve patient-reported outcomes. Furthermore, the use of these technologies may help reduce the risk of acute complications, such as severe hypoglycaemia and diabetic ketoacidosis, as well as long-term macro- and microvascular complications. In addition, diabetes technology can have a beneficial impact on psychosocial health by reducing the burden of diabetes...
January 22, 2018: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/29355928/physician-market-structure-patient-outcomes-and-spending-an-examination-of-medicare-beneficiaries
#9
Thomas Koch, Brett Wendling, Nathan E Wilson
OBJECTIVE: To understand the impact of changes in physician market structure on clinical outcomes and health care utilization. DATA SOURCES: 2005-2012 Medicare fee-for-service claims and enrollment data. STUDY DESIGN: We consider the effect of cardiology market structure on utilization and health outcomes for four patient populations. We estimate the risk-adjusted impact of competition using multivariate regression models. PRINCIPAL FINDINGS: The study finds that an increase in consolidation leads to statistically and economically significant increases in negative health outcomes...
January 22, 2018: Health Services Research
https://www.readbyqxmd.com/read/29355924/adolescent-perspectives-on-the-burden-of-a-parent-s-migraine-results-from-the-cameo-study
#10
Dawn C Buse, Scott W Powers, Amy A Gelfand, Juliana H VanderPluym, Kristina M Fanning, Michael L Reed, Aubrey Manack Adams, Richard B Lipton
OBJECTIVE: To assess the impact of parental migraine on adolescents (aged 13-21 years) living within the parental home from the adolescent's perspective. BACKGROUND: Family members are affected by their parent's migraine. We surveyed adolescents on the social, academic, and emotional effects of their parent's migraine. METHODS: The Chronic Migraine Epidemiology and Outcomes (CaMEO) study was a longitudinal Web-based study with cross-sectional modules designed to assess migraine symptoms, severity, frequency, and disability; migraine-related consulting practices, healthcare utilization, medication use, comorbid health conditions, and family related burden associated with migraine...
January 22, 2018: Headache
https://www.readbyqxmd.com/read/29355811/preoperative-hemoglobin-level-is-associated-with-increased-healthcare-utilization-after-elective-spinal-fusion-%C3%A2-3-levels-in-elderly-male-spine-deformity-patients
#11
Aladine A Elsamadicy, Owoicho Adogwa, Michael Ongele, Amanda R Sergesketter, Aaron Tarnasky, David E T Lubkin, Nicolas Drysdale, Joseph Cheng, Carlos A Bagley, Isaac O Karikari
BACKGROUND: Measures of healthcare utilization such as length of hospital stay (LOS) are used as proxies for quality of care after spine surgery. Accordingly, hospitals and health systems are investing considerable resources into the pre-operative identification of patients at risk for prolonged LOS. This study aims to investigate the impact of preoperative hemoglobin on outcomes and LOS after spinal fusion. METHODS: The medical records of 204 elderly (≥60 years) male patients undergoing elective spinal fusion (≥3 levels) at a major academic institution from 2005 to 2015 were reviewed...
January 17, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29355687/key-acceptability-attributes-of-orodispersible-films
#12
Mariagiovanna Scarpa, Amrit Paudel, Frank Kloprogge, Wen Kai Hsiao, Massimo Bresciani, Simon Gaisford, Mine Orlu
The features rendering ODFs as patient-centric formulations are widely discussed in the scientific literature. However there is a lack of research studies exploring ODF characteristics with a potential impact on end-user acceptability. The aim of this study was to identify the key ODF characteristics affecting end-user acceptability by developing in vitro test methods for the prediction of ODFs acceptability and correlate these formulation characteristics with the data obtained from human panel study. Four drug-free single-polymer films were prepared by solvent casting...
January 17, 2018: European Journal of Pharmaceutics and Biopharmaceutics
https://www.readbyqxmd.com/read/29355548/treating-cough-due-to-non-cf-and-cf-bronchiectasis-with-non-pharmacological-airway-clearance-chest-expert-panel-report
#13
Adam T Hill, Alan F Barker, Donald C Bolser, Paul Davenport, Belinda Ireland, Anne B Chang, Stuart B Mazzone, Lorcan McGarvey
BACKGROUND: In bronchiectasis, due to cystic fibrosis (CF) and other causes, airways clearance is one of the mainstays of management. We conducted a systematic review on airways clearance using non-pharmacological methods as recommended by international guidelines to develop recommendations or suggestions to update the 2006 CHEST guideline on cough. METHODS: The systematic search for evidence examined the question, "Is there evidence of clinically important treatment effects for non-pharmacological therapies in cough treatment for patients with bronchiectasis?"...
January 17, 2018: Chest
https://www.readbyqxmd.com/read/29355520/impact-of-capsule-endoscopy-on-prevention-of-postoperative-recurrence-of-crohn-s-disease
#14
Ze-Min Han, Wei-Guang Qiao, Xiu-Yun Ai, Ai-Min Li, Zhen-Yu Chen, Xi-Cheng Feng, Jie Zhang, Tian-Mo Wan, Zhi-Min Xu, Yang Bai, Ming-Song Li, Si-de Liu, Fa-Chao Zhi
BACKGROUND AND AIMS: Capsule endoscopy (CE) could detect lesions outside the scope of ileocolonoscopy in postoperative patients with Crohn's disease (CD). However, the impact of such findings on patient outcomes remains unknown. This study is intended to evaluate the impact of CE findings on clinical management and outcomes in asymptomatic patients with CD without pharmacological prophylaxis after ileocolonic resection. METHODS: In this retrospective cohort study, 37 patients (group 1) received ileocolonoscopy together with CE within 1 year after surgery, whereas 46 patients (group 2) only received ileocolonoscopy...
January 17, 2018: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29355380/electrocardiographic-outcome-of-resynchronization-therapy
#15
O Kittnar, L Riedlbauchová, J Tomis, M LoŽek, A Valeriánová, M Hrachovina, M Mlček, M Huptych, J Janoušek, L Lhotská
Cardiac resynchronization therapy (CRT) has proven efficacious in reducing or even eliminating cardiac dyssynchrony and thus improving heart failure symptoms. However, quantification of mechanical dyssynchrony is still difficult and identification of CRT candidates is currently based just on the morphology and width of the QRS complex. As standard 12-lead ECG brings only limited information about the pattern of ventricular activation, we aimed to study changes produced by different pacing modes on the body surface potential maps (BSPM)...
December 30, 2017: Physiological Research
https://www.readbyqxmd.com/read/29355116/focusing-on-employment-in-primary-mental-health-care-a-scoping-review
#16
Kirk Reed, Halina Kalaga
BACKGROUND: People with mental health issues usually access primary health care services but employment status and/or return to work is not typically an explicit focus of a general practice consultation. OBJECTIVE: This scoping review aims to investigate the broad range of interventions used in primary health care to effectively support people with mental health issues to choose, get, or keep employment. METHODS: A literature search was conducted using five electronic databases...
January 19, 2018: Work: a Journal of Prevention, Assessment, and Rehabilitation
https://www.readbyqxmd.com/read/29354743/national-outcomes-following-single-level-cervical-disc-arthroplasty-versus-anterior-cervical-discectomy-and-fusion
#17
Jamal Shillingford, Joseph Laratta, Nathan Hardy, Comron Saifi, Joseph Lombardi, Andrew J Pugely, Ronald A Lehman, K Daniel Riew
Background: To compare the differences in the thirty-day postoperative outcomes between cervical disc arthroplasty (CDA) and anterior cervical discectomy and fusion (ACDF). Methods: Patients undergoing primary single-level ACDF and CDA from 2010-2014 were identified by unique Current Procedural Terminology (CPT) codes within the American College of Surgeon's National Surgical Quality Improvement Program (NSQIP) database. Primary outcomes included surgical and medical complications, length of hospital stay (LOS), unplanned readmission, return to operating room, and mortality all occurring within 30 days of the initial procedure...
December 2017: Journal of Spine Surgery (Hong Kong)
https://www.readbyqxmd.com/read/29354514/the-impact-of-perioperative-blood-transfusion-on-survival-outcomes-in-radical-cystectomy-patients
#18
EDITORIAL
Marco Moschini
No abstract text is available yet for this article.
December 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/29354488/impact-of-the-ki-67-labeling-index-and-p53-expression-status-on-disease-free-survival-in-pt1-urothelial-carcinoma-of-the-bladder
#19
Malte W Vetterlein, Julia Roschinski, Philipp Gild, Phillip Marks, Armin Soave, Ousman Doh, Hendrik Isbarn, Wolfgang Höppner, Walter Wagner, Shahrokh F Shariat, Maurizio Brausi, Franziska Büscheck, Guido Sauter, Margit Fisch, Michael Rink
Background: The identification of protein biomarkers to guide treatment decisions regarding adjuvant therapies for high-risk non-muscle-invasive bladder cancer (NMIBC) has been of increasing interest. Evidence of the impact of tumor suppressor gene product p53 and cell proliferation marker Ki-67 on oncologic outcomes in bladder cancer patients at highest risk of recurrence and progression is partially contradictory. We sought to mirror contemporary expression patterns of p53 and Ki-67 in a select cohort of patients with pT1 bladder cancer...
December 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/29354241/the-potential-of-diffusion-weighted-magnetic-resonance-imaging-for-predicting-the-outcomes-of-chronic-subdural-hematomas
#20
Seung-Hwan Lee, Jong-Il Choi, Dong-Jun Lim, Sung-Kon Ha, Sang-Dae Kim, Se-Hoon Kim
Objective: Diffusion-weighted magnetic resonance imaging (DW-MRI) has proven useful in the study of the natural history of ischemic stroke. However, the potential of DW-MRI for the evaluation of chronic subdural hematoma (CSDH) has not been established. In this study, we investigated DW-MRI findings of CSDH and evaluated the impact of the image findings on postoperative outcomes of CSDH. Methods: We studied 131 CSDH patients who had undergone single burr hole drainage surgery...
January 2018: Journal of Korean Neurosurgical Society
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